<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY center_name="GEO" alias="GSE125405" accession="SRP181054">
    <IDENTIFIERS>
      <PRIMARY_ID>SRP181054</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA516229</EXTERNAL_ID>
      <EXTERNAL_ID namespace="GEO">GSE125405</EXTERNAL_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>AKGs enriched transcripts associated with PC-, lyso-PC and PAF metabolism</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Transcriptome Analysis"/>
      <STUDY_ABSTRACT>AKGs enriched transcripts associated with PC-, lyso-PC and PAF metabolism. Moreover, AKGs suppressed interferon response genes. We submit heren three sets of NGS analyses. Experiment 1: We treated mouse adipose tissue macrophages (ATMs) with vehicle (ethanol) or 100 nM alkylglycerols (AKGs) for 18h in vitro. Experiment 2: We treated mouse 3T3-L1 preadipocytes with 1 nM neuropeptide FF (NPFF) for 18 h. Experiment 3: we isolated white adipose tissue from C57Black/6 male mice at 8 weeks of age, and brown adipose tissue from the same mice. Overall design: Experiment 1: 3 Vehicle-treated, and 3 AKG-treated samples. Experiment 2: 3 Vehicle-treated and 3 NPFF-treated samples. Experiment 3: 3 white adipose tissue (Bveh) and 3 brown adipose tissue (BAKG). In the latter case the sample naming refers to the project acronyms.</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>GSE125405</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
    <STUDY_LINKS>
      <STUDY_LINK>
        <XREF_LINK>
          <DB>pubmed</DB>
          <ID>31081799</ID>
        </XREF_LINK>
      </STUDY_LINK>
      <STUDY_LINK>
        <XREF_LINK>
          <DB>pubmed</DB>
          <ID>34572017</ID>
        </XREF_LINK>
      </STUDY_LINK>
    </STUDY_LINKS>
  </STUDY>
</STUDY_SET>
