SRX5620694 GSM3701148 SRP190031 SRS4566851 GSM3701148 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using Quiagen micro RNA purification kit The RNA was pre-amplified and converted to cDNA using Nugen Ovation RNA-seq System V2. Amplified cDNA was sonicated 10 cycles on a BioRupture (30sec on, 30sec off, High setting) and RNA-seq libraries were generated. Quantity and quality of the libraries was performed using Qubit HS assay, KAPA Biosystems library quantification kit for Illumina platforms and Agilent High Sensitivity DNA Assay. Next generation sequencing of the libraries was performed on a Nextseq 500 (Illumina). Reads where mapped using RNA STAR16 (Galaxy Version 2.4.0d-2) mapped reads where counted using htseq-count17 (Galaxy Version 0.6.1galaxy1). Differentially expressed genes were identified using DESeq218 (Galaxy Version 2.1.8.3). NextSeq 500 gds 303701148 GSM3701148 GEO Accession GSM3701148 SRX5620695 GSM3701149 SRP190031 SRS4566853 GSM3701149 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using Quiagen micro RNA purification kit The RNA was pre-amplified and converted to cDNA using Nugen Ovation RNA-seq System V2. Amplified cDNA was sonicated 10 cycles on a BioRupture (30sec on, 30sec off, High setting) and RNA-seq libraries were generated. Quantity and quality of the libraries was performed using Qubit HS assay, KAPA Biosystems library quantification kit for Illumina platforms and Agilent High Sensitivity DNA Assay. Next generation sequencing of the libraries was performed on a Nextseq 500 (Illumina). Reads where mapped using RNA STAR16 (Galaxy Version 2.4.0d-2) mapped reads where counted using htseq-count17 (Galaxy Version 0.6.1galaxy1). Differentially expressed genes were identified using DESeq218 (Galaxy Version 2.1.8.3). NextSeq 500 gds 303701149 GSM3701149 GEO Accession GSM3701149 SRX5620696 GSM3701150 SRP190031 SRS4566856 GSM3701150 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using Quiagen micro RNA purification kit The RNA was pre-amplified and converted to cDNA using Nugen Ovation RNA-seq System V2. Amplified cDNA was sonicated 10 cycles on a BioRupture (30sec on, 30sec off, High setting) and RNA-seq libraries were generated. Quantity and quality of the libraries was performed using Qubit HS assay, KAPA Biosystems library quantification kit for Illumina platforms and Agilent High Sensitivity DNA Assay. Next generation sequencing of the libraries was performed on a Nextseq 500 (Illumina). Reads where mapped using RNA STAR16 (Galaxy Version 2.4.0d-2) mapped reads where counted using htseq-count17 (Galaxy Version 0.6.1galaxy1). Differentially expressed genes were identified using DESeq218 (Galaxy Version 2.1.8.3). NextSeq 500 gds 303701150 GSM3701150 GEO Accession GSM3701150 SRX5620697 GSM3701151 SRP190031 SRS4566854 GSM3701151 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using Quiagen micro RNA purification kit The RNA was pre-amplified and converted to cDNA using Nugen Ovation RNA-seq System V2. Amplified cDNA was sonicated 10 cycles on a BioRupture (30sec on, 30sec off, High setting) and RNA-seq libraries were generated. Quantity and quality of the libraries was performed using Qubit HS assay, KAPA Biosystems library quantification kit for Illumina platforms and Agilent High Sensitivity DNA Assay. Next generation sequencing of the libraries was performed on a Nextseq 500 (Illumina). Reads where mapped using RNA STAR16 (Galaxy Version 2.4.0d-2) mapped reads where counted using htseq-count17 (Galaxy Version 0.6.1galaxy1). Differentially expressed genes were identified using DESeq218 (Galaxy Version 2.1.8.3). NextSeq 500 gds 303701151 GSM3701151 GEO Accession GSM3701151 SRX5620698 GSM3701152 SRP190031 SRS4566857 GSM3701152 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using Quiagen micro RNA purification kit The RNA was pre-amplified and converted to cDNA using Nugen Ovation RNA-seq System V2. Amplified cDNA was sonicated 10 cycles on a BioRupture (30sec on, 30sec off, High setting) and RNA-seq libraries were generated. Quantity and quality of the libraries was performed using Qubit HS assay, KAPA Biosystems library quantification kit for Illumina platforms and Agilent High Sensitivity DNA Assay. Next generation sequencing of the libraries was performed on a Nextseq 500 (Illumina). Reads where mapped using RNA STAR16 (Galaxy Version 2.4.0d-2) mapped reads where counted using htseq-count17 (Galaxy Version 0.6.1galaxy1). Differentially expressed genes were identified using DESeq218 (Galaxy Version 2.1.8.3). NextSeq 500 gds 303701152 GSM3701152 GEO Accession GSM3701152 SRX5620699 GSM3701153 SRP190031 SRS4566855 GSM3701153 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using Quiagen micro RNA purification kit The RNA was pre-amplified and converted to cDNA using Nugen Ovation RNA-seq System V2. Amplified cDNA was sonicated 10 cycles on a BioRupture (30sec on, 30sec off, High setting) and RNA-seq libraries were generated. Quantity and quality of the libraries was performed using Qubit HS assay, KAPA Biosystems library quantification kit for Illumina platforms and Agilent High Sensitivity DNA Assay. Next generation sequencing of the libraries was performed on a Nextseq 500 (Illumina). Reads where mapped using RNA STAR16 (Galaxy Version 2.4.0d-2) mapped reads where counted using htseq-count17 (Galaxy Version 0.6.1galaxy1). Differentially expressed genes were identified using DESeq218 (Galaxy Version 2.1.8.3). NextSeq 500 gds 303701153 GSM3701153 GEO Accession GSM3701153 SRX5620700 GSM3701154 SRP190031 SRS4566859 GSM3701154 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using Quiagen micro RNA purification kit The RNA was pre-amplified and converted to cDNA using Nugen Ovation RNA-seq System V2. Amplified cDNA was sonicated 10 cycles on a BioRupture (30sec on, 30sec off, High setting) and RNA-seq libraries were generated. Quantity and quality of the libraries was performed using Qubit HS assay, KAPA Biosystems library quantification kit for Illumina platforms and Agilent High Sensitivity DNA Assay. Next generation sequencing of the libraries was performed on a Nextseq 500 (Illumina). Reads where mapped using RNA STAR16 (Galaxy Version 2.4.0d-2) mapped reads where counted using htseq-count17 (Galaxy Version 0.6.1galaxy1). Differentially expressed genes were identified using DESeq218 (Galaxy Version 2.1.8.3). NextSeq 500 gds 303701154 GSM3701154 GEO Accession GSM3701154 SRX5620701 GSM3701155 SRP190031 SRS4566860 GSM3701155 RNA-Seq TRANSCRIPTOMIC cDNA Total RNA was extracted using Quiagen micro RNA purification kit The RNA was pre-amplified and converted to cDNA using Nugen Ovation RNA-seq System V2. Amplified cDNA was sonicated 10 cycles on a BioRupture (30sec on, 30sec off, High setting) and RNA-seq libraries were generated. Quantity and quality of the libraries was performed using Qubit HS assay, KAPA Biosystems library quantification kit for Illumina platforms and Agilent High Sensitivity DNA Assay. Next generation sequencing of the libraries was performed on a Nextseq 500 (Illumina). Reads where mapped using RNA STAR16 (Galaxy Version 2.4.0d-2) mapped reads where counted using htseq-count17 (Galaxy Version 0.6.1galaxy1). Differentially expressed genes were identified using DESeq218 (Galaxy Version 2.1.8.3). NextSeq 500 gds 303701155 GSM3701155 GEO Accession GSM3701155