SRX5624028 GSM3701992 SRP190128 SRS4569197 GSM3701992 ChIP-Seq GENOMIC ChIP Chromatin immunoprecipitation (ChIP) was performed as previously described (Frank et al., 2001) with minor modifications outlined below. Chromatin was fixed with 1% Formaldehyde (Sigma-Aldrich) for 10 minutes and sonicated on a bioruptor (Diagenode) to produce fragments of 100-500 bp, and ChIPs performed with Protein G-coupled magnetic Dynabeads (Invitrogen) and the following antibodies : 8 µg MED1 (A300-793A Bethyl Laboratories). The amounts of chromatin (protein) used in each ChIP were as follows: 800 µg (Med1). Following washes of bound DNA-protein complexes, DNA was eluted in 1% SDS and treated with 40 ng/µl RNaseA following 0.2 µg/µl Proteinase K. After phenol/chloroform purification, DNA was then precipitated at -20°C with 20-30 μg GlycoBlue carrier (Invitrogen), 1/10 volumes of 3 M NaAc and 2 volumes of 100% ethanol. Sequencing libraries were prepared using the NEBNext® UltraTM DNA Library Prep Kit and Multiplex Oligos (New England Biolabs) from 5 ng of DNA. Following analysis on an Agilent Bioanalyzer, libraries were pooled and sequenced on an Illumina NextSeq500. NextSeq 500 gds 303701992 GSM3701992 GEO Accession GSM3701992 SRX5624029 GSM3701993 SRP190128 SRS4569199 GSM3701993 ChIP-Seq GENOMIC ChIP Chromatin immunoprecipitation (ChIP) was performed as previously described (Frank et al., 2001) with minor modifications outlined below. Chromatin was fixed with 1% Formaldehyde (Sigma-Aldrich) for 10 minutes and sonicated on a bioruptor (Diagenode) to produce fragments of 100-500 bp, and ChIPs performed with Protein G-coupled magnetic Dynabeads (Invitrogen) and the following antibodies : 8 µg MED1 (A300-793A Bethyl Laboratories). The amounts of chromatin (protein) used in each ChIP were as follows: 800 µg (Med1). Following washes of bound DNA-protein complexes, DNA was eluted in 1% SDS and treated with 40 ng/µl RNaseA following 0.2 µg/µl Proteinase K. After phenol/chloroform purification, DNA was then precipitated at -20°C with 20-30 μg GlycoBlue carrier (Invitrogen), 1/10 volumes of 3 M NaAc and 2 volumes of 100% ethanol. Sequencing libraries were prepared using the NEBNext® UltraTM DNA Library Prep Kit and Multiplex Oligos (New England Biolabs) from 5 ng of DNA. Following analysis on an Agilent Bioanalyzer, libraries were pooled and sequenced on an Illumina NextSeq500. NextSeq 500 gds 303701993 GSM3701993 GEO Accession GSM3701993 SRX5624030 GSM3701994 SRP190128 SRS4569198 GSM3701994 ChIP-Seq GENOMIC ChIP Chromatin immunoprecipitation (ChIP) was performed as previously described (Frank et al., 2001) with minor modifications outlined below. Chromatin was fixed with 1% Formaldehyde (Sigma-Aldrich) for 10 minutes and sonicated on a bioruptor (Diagenode) to produce fragments of 100-500 bp, and ChIPs performed with Protein G-coupled magnetic Dynabeads (Invitrogen) and the following antibodies : 8 µg MED1 (A300-793A Bethyl Laboratories). The amounts of chromatin (protein) used in each ChIP were as follows: 800 µg (Med1). Following washes of bound DNA-protein complexes, DNA was eluted in 1% SDS and treated with 40 ng/µl RNaseA following 0.2 µg/µl Proteinase K. After phenol/chloroform purification, DNA was then precipitated at -20°C with 20-30 μg GlycoBlue carrier (Invitrogen), 1/10 volumes of 3 M NaAc and 2 volumes of 100% ethanol. Sequencing libraries were prepared using the NEBNext® UltraTM DNA Library Prep Kit and Multiplex Oligos (New England Biolabs) from 5 ng of DNA. Following analysis on an Agilent Bioanalyzer, libraries were pooled and sequenced on an Illumina NextSeq500. NextSeq 500 gds 303701994 GSM3701994 GEO Accession GSM3701994 SRX5624031 GSM3701995 SRP190128 SRS4569201 GSM3701995 ChIP-Seq GENOMIC ChIP Chromatin immunoprecipitation (ChIP) was performed as previously described (Frank et al., 2001) with minor modifications outlined below. Chromatin was fixed with 1% Formaldehyde (Sigma-Aldrich) for 10 minutes and sonicated on a bioruptor (Diagenode) to produce fragments of 100-500 bp, and ChIPs performed with Protein G-coupled magnetic Dynabeads (Invitrogen) and the following antibodies : 8 µg MED1 (A300-793A Bethyl Laboratories). The amounts of chromatin (protein) used in each ChIP were as follows: 800 µg (Med1). Following washes of bound DNA-protein complexes, DNA was eluted in 1% SDS and treated with 40 ng/µl RNaseA following 0.2 µg/µl Proteinase K. After phenol/chloroform purification, DNA was then precipitated at -20°C with 20-30 μg GlycoBlue carrier (Invitrogen), 1/10 volumes of 3 M NaAc and 2 volumes of 100% ethanol. Sequencing libraries were prepared using the NEBNext® UltraTM DNA Library Prep Kit and Multiplex Oligos (New England Biolabs) from 5 ng of DNA. Following analysis on an Agilent Bioanalyzer, libraries were pooled and sequenced on an Illumina NextSeq500. NextSeq 500 gds 303701995 GSM3701995 GEO Accession GSM3701995 SRX5624032 GSM3701996 SRP190128 SRS4569200 GSM3701996 ChIP-Seq GENOMIC ChIP Chromatin immunoprecipitation (ChIP) was performed as previously described (Frank et al., 2001) with minor modifications outlined below. Chromatin was fixed with 1% Formaldehyde (Sigma-Aldrich) for 10 minutes and sonicated on a bioruptor (Diagenode) to produce fragments of 100-500 bp, and ChIPs performed with Protein G-coupled magnetic Dynabeads (Invitrogen) and the following antibodies : 8 µg MED1 (A300-793A Bethyl Laboratories). The amounts of chromatin (protein) used in each ChIP were as follows: 800 µg (Med1). Following washes of bound DNA-protein complexes, DNA was eluted in 1% SDS and treated with 40 ng/µl RNaseA following 0.2 µg/µl Proteinase K. After phenol/chloroform purification, DNA was then precipitated at -20°C with 20-30 μg GlycoBlue carrier (Invitrogen), 1/10 volumes of 3 M NaAc and 2 volumes of 100% ethanol. Sequencing libraries were prepared using the NEBNext® UltraTM DNA Library Prep Kit and Multiplex Oligos (New England Biolabs) from 5 ng of DNA. Following analysis on an Agilent Bioanalyzer, libraries were pooled and sequenced on an Illumina NextSeq500. NextSeq 500 gds 303701996 GSM3701996 GEO Accession GSM3701996 SRX5624033 GSM3701997 SRP190128 SRS4569202 GSM3701997 ChIP-Seq GENOMIC ChIP Chromatin immunoprecipitation (ChIP) was performed as previously described (Frank et al., 2001) with minor modifications outlined below. Chromatin was fixed with 1% Formaldehyde (Sigma-Aldrich) for 10 minutes and sonicated on a bioruptor (Diagenode) to produce fragments of 100-500 bp, and ChIPs performed with Protein G-coupled magnetic Dynabeads (Invitrogen) and the following antibodies : 8 µg MED1 (A300-793A Bethyl Laboratories). The amounts of chromatin (protein) used in each ChIP were as follows: 800 µg (Med1). Following washes of bound DNA-protein complexes, DNA was eluted in 1% SDS and treated with 40 ng/µl RNaseA following 0.2 µg/µl Proteinase K. After phenol/chloroform purification, DNA was then precipitated at -20°C with 20-30 μg GlycoBlue carrier (Invitrogen), 1/10 volumes of 3 M NaAc and 2 volumes of 100% ethanol. Sequencing libraries were prepared using the NEBNext® UltraTM DNA Library Prep Kit and Multiplex Oligos (New England Biolabs) from 5 ng of DNA. Following analysis on an Agilent Bioanalyzer, libraries were pooled and sequenced on an Illumina NextSeq500. NextSeq 500 gds 303701997 GSM3701997 GEO Accession GSM3701997 SRX5624034 GSM3701998 SRP190128 SRS4569203 GSM3701998 ChIP-Seq GENOMIC ChIP Chromatin immunoprecipitation (ChIP) was performed as previously described (Frank et al., 2001) with minor modifications outlined below. Chromatin was fixed with 1% Formaldehyde (Sigma-Aldrich) for 10 minutes and sonicated on a bioruptor (Diagenode) to produce fragments of 100-500 bp, and ChIPs performed with Protein G-coupled magnetic Dynabeads (Invitrogen) and the following antibodies : 8 µg MED1 (A300-793A Bethyl Laboratories). The amounts of chromatin (protein) used in each ChIP were as follows: 800 µg (Med1). Following washes of bound DNA-protein complexes, DNA was eluted in 1% SDS and treated with 40 ng/µl RNaseA following 0.2 µg/µl Proteinase K. After phenol/chloroform purification, DNA was then precipitated at -20°C with 20-30 μg GlycoBlue carrier (Invitrogen), 1/10 volumes of 3 M NaAc and 2 volumes of 100% ethanol. Sequencing libraries were prepared using the NEBNext® UltraTM DNA Library Prep Kit and Multiplex Oligos (New England Biolabs) from 5 ng of DNA. Following analysis on an Agilent Bioanalyzer, libraries were pooled and sequenced on an Illumina NextSeq500. NextSeq 500 gds 303701998 GSM3701998 GEO Accession GSM3701998 SRX5624035 GSM3701999 SRP190128 SRS4569204 GSM3701999 ChIP-Seq GENOMIC ChIP Chromatin immunoprecipitation (ChIP) was performed as previously described (Frank et al., 2001) with minor modifications outlined below. Chromatin was fixed with 1% Formaldehyde (Sigma-Aldrich) for 10 minutes and sonicated on a bioruptor (Diagenode) to produce fragments of 100-500 bp, and ChIPs performed with Protein G-coupled magnetic Dynabeads (Invitrogen) and the following antibodies : 8 µg MED1 (A300-793A Bethyl Laboratories). The amounts of chromatin (protein) used in each ChIP were as follows: 800 µg (Med1). Following washes of bound DNA-protein complexes, DNA was eluted in 1% SDS and treated with 40 ng/µl RNaseA following 0.2 µg/µl Proteinase K. After phenol/chloroform purification, DNA was then precipitated at -20°C with 20-30 μg GlycoBlue carrier (Invitrogen), 1/10 volumes of 3 M NaAc and 2 volumes of 100% ethanol. Sequencing libraries were prepared using the NEBNext® UltraTM DNA Library Prep Kit and Multiplex Oligos (New England Biolabs) from 5 ng of DNA. Following analysis on an Agilent Bioanalyzer, libraries were pooled and sequenced on an Illumina NextSeq500. NextSeq 500 gds 303701999 GSM3701999 GEO Accession GSM3701999 SRX5624036 GSM3702000 SRP190128 SRS4569205 GSM3702000 ChIP-Seq GENOMIC ChIP Chromatin immunoprecipitation (ChIP) was performed as previously described (Frank et al., 2001) with minor modifications outlined below. Chromatin was fixed with 1% Formaldehyde (Sigma-Aldrich) for 10 minutes and sonicated on a bioruptor (Diagenode) to produce fragments of 100-500 bp, and ChIPs performed with Protein G-coupled magnetic Dynabeads (Invitrogen) and the following antibodies : 8 µg MED1 (A300-793A Bethyl Laboratories). The amounts of chromatin (protein) used in each ChIP were as follows: 800 µg (Med1). Following washes of bound DNA-protein complexes, DNA was eluted in 1% SDS and treated with 40 ng/µl RNaseA following 0.2 µg/µl Proteinase K. After phenol/chloroform purification, DNA was then precipitated at -20°C with 20-30 μg GlycoBlue carrier (Invitrogen), 1/10 volumes of 3 M NaAc and 2 volumes of 100% ethanol. Sequencing libraries were prepared using the NEBNext® UltraTM DNA Library Prep Kit and Multiplex Oligos (New England Biolabs) from 5 ng of DNA. Following analysis on an Agilent Bioanalyzer, libraries were pooled and sequenced on an Illumina NextSeq500. NextSeq 500 gds 303702000 GSM3702000 GEO Accession GSM3702000 SRX5624037 GSM3702001 SRP190128 SRS4569206 GSM3702001 ChIP-Seq GENOMIC ChIP Chromatin immunoprecipitation (ChIP) was performed as previously described (Frank et al., 2001) with minor modifications outlined below. Chromatin was fixed with 1% Formaldehyde (Sigma-Aldrich) for 10 minutes and sonicated on a bioruptor (Diagenode) to produce fragments of 100-500 bp, and ChIPs performed with Protein G-coupled magnetic Dynabeads (Invitrogen) and the following antibodies : 8 µg MED1 (A300-793A Bethyl Laboratories). The amounts of chromatin (protein) used in each ChIP were as follows: 800 µg (Med1). Following washes of bound DNA-protein complexes, DNA was eluted in 1% SDS and treated with 40 ng/µl RNaseA following 0.2 µg/µl Proteinase K. After phenol/chloroform purification, DNA was then precipitated at -20°C with 20-30 μg GlycoBlue carrier (Invitrogen), 1/10 volumes of 3 M NaAc and 2 volumes of 100% ethanol. Sequencing libraries were prepared using the NEBNext® UltraTM DNA Library Prep Kit and Multiplex Oligos (New England Biolabs) from 5 ng of DNA. Following analysis on an Agilent Bioanalyzer, libraries were pooled and sequenced on an Illumina NextSeq500. NextSeq 500 gds 303702001 GSM3702001 GEO Accession GSM3702001 SRX5624038 GSM3702002 SRP190128 SRS4569207 GSM3702002 ChIP-Seq GENOMIC ChIP Chromatin immunoprecipitation (ChIP) was performed as previously described (Frank et al., 2001) with minor modifications outlined below. Chromatin was fixed with 1% Formaldehyde (Sigma-Aldrich) for 10 minutes and sonicated on a bioruptor (Diagenode) to produce fragments of 100-500 bp, and ChIPs performed with Protein G-coupled magnetic Dynabeads (Invitrogen) and the following antibodies : 8 µg MED1 (A300-793A Bethyl Laboratories). The amounts of chromatin (protein) used in each ChIP were as follows: 800 µg (Med1). Following washes of bound DNA-protein complexes, DNA was eluted in 1% SDS and treated with 40 ng/µl RNaseA following 0.2 µg/µl Proteinase K. After phenol/chloroform purification, DNA was then precipitated at -20°C with 20-30 μg GlycoBlue carrier (Invitrogen), 1/10 volumes of 3 M NaAc and 2 volumes of 100% ethanol. Sequencing libraries were prepared using the NEBNext® UltraTM DNA Library Prep Kit and Multiplex Oligos (New England Biolabs) from 5 ng of DNA. Following analysis on an Agilent Bioanalyzer, libraries were pooled and sequenced on an Illumina NextSeq500. NextSeq 500 gds 303702002 GSM3702002 GEO Accession GSM3702002 SRX5624039 GSM3702003 SRP190128 SRS4569208 GSM3702003 ChIP-Seq GENOMIC ChIP Chromatin immunoprecipitation (ChIP) was performed as previously described (Frank et al., 2001) with minor modifications outlined below. Chromatin was fixed with 1% Formaldehyde (Sigma-Aldrich) for 10 minutes and sonicated on a bioruptor (Diagenode) to produce fragments of 100-500 bp, and ChIPs performed with Protein G-coupled magnetic Dynabeads (Invitrogen) and the following antibodies : 8 µg MED1 (A300-793A Bethyl Laboratories). The amounts of chromatin (protein) used in each ChIP were as follows: 800 µg (Med1). Following washes of bound DNA-protein complexes, DNA was eluted in 1% SDS and treated with 40 ng/µl RNaseA following 0.2 µg/µl Proteinase K. After phenol/chloroform purification, DNA was then precipitated at -20°C with 20-30 μg GlycoBlue carrier (Invitrogen), 1/10 volumes of 3 M NaAc and 2 volumes of 100% ethanol. Sequencing libraries were prepared using the NEBNext® UltraTM DNA Library Prep Kit and Multiplex Oligos (New England Biolabs) from 5 ng of DNA. Following analysis on an Agilent Bioanalyzer, libraries were pooled and sequenced on an Illumina NextSeq500. NextSeq 500 gds 303702003 GSM3702003 GEO Accession GSM3702003