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    <TITLE>GSM3753962: A_LV_S108 ATACseq; Homo sapiens; ATAC-seq</TITLE>
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        <LIBRARY_CONSTRUCTION_PROTOCOL>Mononuclear cells from mesenteric LN, TDL, and PBMC were thawed, rested overnight, and sorted in cell numbers of 5-25,000 into complete RPMI with 50% FBS. Nuclei from cell pellets (5,000-25,000 cells) were isolated using a lysis buffer and pelleted in low-bind 1.5mL tubes (Eppendorf). Nuclei were resuspended in 25ml TD buffer with Tn transposase (Illumina). The transposition reaction was continued for 45 minutes at 37°C. The resulting DNA fragments were purified using the MinElute PCR purification Kit (Qiagen). Libraries were prepared using Nextera (Illumina) and sequenced by the Children's Hospital of Philadelphia partnership with the Bejing Genomics Institute on two lanes of a Hiseq 4000 paired-end sequencing (100 bp read length).</LIBRARY_CONSTRUCTION_PROTOCOL>
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        <INSTRUMENT_MODEL>NextSeq 500</INSTRUMENT_MODEL>
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          <DB>gds</DB>
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      <PRIMARY_ID>SRX5799585</PRIMARY_ID>
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    <TITLE>GSM3753963: A_LV_S110 ATACseq; Homo sapiens; ATAC-seq</TITLE>
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        <LIBRARY_CONSTRUCTION_PROTOCOL>Mononuclear cells from mesenteric LN, TDL, and PBMC were thawed, rested overnight, and sorted in cell numbers of 5-25,000 into complete RPMI with 50% FBS. Nuclei from cell pellets (5,000-25,000 cells) were isolated using a lysis buffer and pelleted in low-bind 1.5mL tubes (Eppendorf). Nuclei were resuspended in 25ml TD buffer with Tn transposase (Illumina). The transposition reaction was continued for 45 minutes at 37°C. The resulting DNA fragments were purified using the MinElute PCR purification Kit (Qiagen). Libraries were prepared using Nextera (Illumina) and sequenced by the Children's Hospital of Philadelphia partnership with the Bejing Genomics Institute on two lanes of a Hiseq 4000 paired-end sequencing (100 bp read length).</LIBRARY_CONSTRUCTION_PROTOCOL>
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        <INSTRUMENT_MODEL>NextSeq 500</INSTRUMENT_MODEL>
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          <DB>gds</DB>
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      <PRIMARY_ID>SRX5799586</PRIMARY_ID>
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    <TITLE>GSM3753964: A_LV_S111 ATACseq; Homo sapiens; ATAC-seq</TITLE>
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        <PRIMARY_ID>SRP195733</PRIMARY_ID>
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      <DESIGN_DESCRIPTION/>
      <SAMPLE_DESCRIPTOR accession="SRS4730612">
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          <PRIMARY_ID>SRS4730612</PRIMARY_ID>
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          <PAIRED/>
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      <ILLUMINA>
        <INSTRUMENT_MODEL>NextSeq 500</INSTRUMENT_MODEL>
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      <EXPERIMENT_LINK>
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          <DB>gds</DB>
          <ID>303753964</ID>
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      <PRIMARY_ID>SRX5799587</PRIMARY_ID>
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    <TITLE>GSM3753965: A_LV_S115 ATACseq; Homo sapiens; ATAC-seq</TITLE>
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        <PRIMARY_ID>SRP195733</PRIMARY_ID>
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      <DESIGN_DESCRIPTION/>
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          <PRIMARY_ID>SRS4730613</PRIMARY_ID>
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        <INSTRUMENT_MODEL>NextSeq 500</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX5799588</PRIMARY_ID>
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    <TITLE>GSM3753966: A_LV_S118 ATACseq; Homo sapiens; ATAC-seq</TITLE>
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      <DESIGN_DESCRIPTION/>
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          <PRIMARY_ID>SRS4730614</PRIMARY_ID>
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        <INSTRUMENT_MODEL>NextSeq 500</INSTRUMENT_MODEL>
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      <PRIMARY_ID>SRX5799589</PRIMARY_ID>
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    <TITLE>GSM3753967: A_LV_S119 ATACseq; Homo sapiens; ATAC-seq</TITLE>
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      <DESIGN_DESCRIPTION/>
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          <PRIMARY_ID>SRS4730615</PRIMARY_ID>
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        <INSTRUMENT_MODEL>NextSeq 500</INSTRUMENT_MODEL>
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      <DESIGN_DESCRIPTION/>
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        <INSTRUMENT_MODEL>NextSeq 500</INSTRUMENT_MODEL>
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      <DESIGN_DESCRIPTION/>
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        <INSTRUMENT_MODEL>NextSeq 500</INSTRUMENT_MODEL>
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      <DESIGN_DESCRIPTION/>
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        <INSTRUMENT_MODEL>NextSeq 500</INSTRUMENT_MODEL>
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      <IDENTIFIERS>
        <PRIMARY_ID>SRP195733</PRIMARY_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION/>
      <SAMPLE_DESCRIPTOR accession="SRS4730620">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS4730620</PRIMARY_ID>
          <EXTERNAL_ID namespace="GEO">GSM3753972</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_STRATEGY>ATAC-seq</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>other</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
        <LIBRARY_CONSTRUCTION_PROTOCOL>Mononuclear cells from mesenteric LN, TDL, and PBMC were thawed, rested overnight, and sorted in cell numbers of 5-25,000 into complete RPMI with 50% FBS. Nuclei from cell pellets (5,000-25,000 cells) were isolated using a lysis buffer and pelleted in low-bind 1.5mL tubes (Eppendorf). Nuclei were resuspended in 25ml TD buffer with Tn transposase (Illumina). The transposition reaction was continued for 45 minutes at 37°C. The resulting DNA fragments were purified using the MinElute PCR purification Kit (Qiagen). Libraries were prepared using Nextera (Illumina) and sequenced by the Children's Hospital of Philadelphia partnership with the Bejing Genomics Institute on two lanes of a Hiseq 4000 paired-end sequencing (100 bp read length).</LIBRARY_CONSTRUCTION_PROTOCOL>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>NextSeq 500</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_LINKS>
      <EXPERIMENT_LINK>
        <XREF_LINK>
          <DB>gds</DB>
          <ID>303753972</ID>
          <LABEL>GSM3753972</LABEL>
        </XREF_LINK>
      </EXPERIMENT_LINK>
    </EXPERIMENT_LINKS>
  </EXPERIMENT>
  <EXPERIMENT alias="GSM3753973" accession="SRX5799595">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX5799595</PRIMARY_ID>
      <SUBMITTER_ID namespace="GEO">GSM3753973</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>GSM3753973: A_LV_S134 ATACseq; Homo sapiens; ATAC-seq</TITLE>
    <STUDY_REF accession="SRP195733" refname="GSE130791">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP195733</PRIMARY_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION/>
      <SAMPLE_DESCRIPTOR accession="SRS4730621">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS4730621</PRIMARY_ID>
          <EXTERNAL_ID namespace="GEO">GSM3753973</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_STRATEGY>ATAC-seq</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>other</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
        <LIBRARY_CONSTRUCTION_PROTOCOL>Mononuclear cells from mesenteric LN, TDL, and PBMC were thawed, rested overnight, and sorted in cell numbers of 5-25,000 into complete RPMI with 50% FBS. Nuclei from cell pellets (5,000-25,000 cells) were isolated using a lysis buffer and pelleted in low-bind 1.5mL tubes (Eppendorf). Nuclei were resuspended in 25ml TD buffer with Tn transposase (Illumina). The transposition reaction was continued for 45 minutes at 37°C. The resulting DNA fragments were purified using the MinElute PCR purification Kit (Qiagen). Libraries were prepared using Nextera (Illumina) and sequenced by the Children's Hospital of Philadelphia partnership with the Bejing Genomics Institute on two lanes of a Hiseq 4000 paired-end sequencing (100 bp read length).</LIBRARY_CONSTRUCTION_PROTOCOL>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>NextSeq 500</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_LINKS>
      <EXPERIMENT_LINK>
        <XREF_LINK>
          <DB>gds</DB>
          <ID>303753973</ID>
          <LABEL>GSM3753973</LABEL>
        </XREF_LINK>
      </EXPERIMENT_LINK>
    </EXPERIMENT_LINKS>
  </EXPERIMENT>
  <EXPERIMENT alias="GSM3753974" accession="SRX5799596">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX5799596</PRIMARY_ID>
      <SUBMITTER_ID namespace="GEO">GSM3753974</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>GSM3753974: A_LV_S138 ATACseq; Homo sapiens; ATAC-seq</TITLE>
    <STUDY_REF accession="SRP195733" refname="GSE130791">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP195733</PRIMARY_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION/>
      <SAMPLE_DESCRIPTOR accession="SRS4730622">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS4730622</PRIMARY_ID>
          <EXTERNAL_ID namespace="GEO">GSM3753974</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_STRATEGY>ATAC-seq</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>other</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
        <LIBRARY_CONSTRUCTION_PROTOCOL>Mononuclear cells from mesenteric LN, TDL, and PBMC were thawed, rested overnight, and sorted in cell numbers of 5-25,000 into complete RPMI with 50% FBS. Nuclei from cell pellets (5,000-25,000 cells) were isolated using a lysis buffer and pelleted in low-bind 1.5mL tubes (Eppendorf). Nuclei were resuspended in 25ml TD buffer with Tn transposase (Illumina). The transposition reaction was continued for 45 minutes at 37°C. The resulting DNA fragments were purified using the MinElute PCR purification Kit (Qiagen). Libraries were prepared using Nextera (Illumina) and sequenced by the Children's Hospital of Philadelphia partnership with the Bejing Genomics Institute on two lanes of a Hiseq 4000 paired-end sequencing (100 bp read length).</LIBRARY_CONSTRUCTION_PROTOCOL>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>NextSeq 500</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_LINKS>
      <EXPERIMENT_LINK>
        <XREF_LINK>
          <DB>gds</DB>
          <ID>303753974</ID>
          <LABEL>GSM3753974</LABEL>
        </XREF_LINK>
      </EXPERIMENT_LINK>
    </EXPERIMENT_LINKS>
  </EXPERIMENT>
  <EXPERIMENT alias="GSM3753960" accession="SRX5799597">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX5799597</PRIMARY_ID>
      <SUBMITTER_ID namespace="GEO">GSM3753960</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>GSM3753960: A_LV_S103 ATACseq; Homo sapiens; ATAC-seq</TITLE>
    <STUDY_REF accession="SRP195733" refname="GSE130791">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP195733</PRIMARY_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION/>
      <SAMPLE_DESCRIPTOR accession="SRS4730623">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS4730623</PRIMARY_ID>
          <EXTERNAL_ID namespace="GEO">GSM3753960</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_STRATEGY>ATAC-seq</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>other</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
        <LIBRARY_CONSTRUCTION_PROTOCOL>Mononuclear cells from mesenteric LN, TDL, and PBMC were thawed, rested overnight, and sorted in cell numbers of 5-25,000 into complete RPMI with 50% FBS. Nuclei from cell pellets (5,000-25,000 cells) were isolated using a lysis buffer and pelleted in low-bind 1.5mL tubes (Eppendorf). Nuclei were resuspended in 25ml TD buffer with Tn transposase (Illumina). The transposition reaction was continued for 45 minutes at 37°C. The resulting DNA fragments were purified using the MinElute PCR purification Kit (Qiagen). Libraries were prepared using Nextera (Illumina) and sequenced by the Children's Hospital of Philadelphia partnership with the Bejing Genomics Institute on two lanes of a Hiseq 4000 paired-end sequencing (100 bp read length).</LIBRARY_CONSTRUCTION_PROTOCOL>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>NextSeq 500</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_LINKS>
      <EXPERIMENT_LINK>
        <XREF_LINK>
          <DB>gds</DB>
          <ID>303753960</ID>
          <LABEL>GSM3753960</LABEL>
        </XREF_LINK>
      </EXPERIMENT_LINK>
    </EXPERIMENT_LINKS>
  </EXPERIMENT>
  <EXPERIMENT alias="GSM3753961" accession="SRX5799598">
    <IDENTIFIERS>
      <PRIMARY_ID>SRX5799598</PRIMARY_ID>
      <SUBMITTER_ID namespace="GEO">GSM3753961</SUBMITTER_ID>
    </IDENTIFIERS>
    <TITLE>GSM3753961: A_LV_S104 ATACseq; Homo sapiens; ATAC-seq</TITLE>
    <STUDY_REF accession="SRP195733" refname="GSE130791">
      <IDENTIFIERS>
        <PRIMARY_ID>SRP195733</PRIMARY_ID>
      </IDENTIFIERS>
    </STUDY_REF>
    <DESIGN>
      <DESIGN_DESCRIPTION/>
      <SAMPLE_DESCRIPTOR accession="SRS4730624">
        <IDENTIFIERS>
          <PRIMARY_ID>SRS4730624</PRIMARY_ID>
          <EXTERNAL_ID namespace="GEO">GSM3753961</EXTERNAL_ID>
        </IDENTIFIERS>
      </SAMPLE_DESCRIPTOR>
      <LIBRARY_DESCRIPTOR>
        <LIBRARY_STRATEGY>ATAC-seq</LIBRARY_STRATEGY>
        <LIBRARY_SOURCE>GENOMIC</LIBRARY_SOURCE>
        <LIBRARY_SELECTION>other</LIBRARY_SELECTION>
        <LIBRARY_LAYOUT>
          <PAIRED/>
        </LIBRARY_LAYOUT>
        <LIBRARY_CONSTRUCTION_PROTOCOL>Mononuclear cells from mesenteric LN, TDL, and PBMC were thawed, rested overnight, and sorted in cell numbers of 5-25,000 into complete RPMI with 50% FBS. Nuclei from cell pellets (5,000-25,000 cells) were isolated using a lysis buffer and pelleted in low-bind 1.5mL tubes (Eppendorf). Nuclei were resuspended in 25ml TD buffer with Tn transposase (Illumina). The transposition reaction was continued for 45 minutes at 37°C. The resulting DNA fragments were purified using the MinElute PCR purification Kit (Qiagen). Libraries were prepared using Nextera (Illumina) and sequenced by the Children's Hospital of Philadelphia partnership with the Bejing Genomics Institute on two lanes of a Hiseq 4000 paired-end sequencing (100 bp read length).</LIBRARY_CONSTRUCTION_PROTOCOL>
      </LIBRARY_DESCRIPTOR>
    </DESIGN>
    <PLATFORM>
      <ILLUMINA>
        <INSTRUMENT_MODEL>NextSeq 500</INSTRUMENT_MODEL>
      </ILLUMINA>
    </PLATFORM>
    <EXPERIMENT_LINKS>
      <EXPERIMENT_LINK>
        <XREF_LINK>
          <DB>gds</DB>
          <ID>303753961</ID>
          <LABEL>GSM3753961</LABEL>
        </XREF_LINK>
      </EXPERIMENT_LINK>
    </EXPERIMENT_LINKS>
  </EXPERIMENT>
</EXPERIMENT_SET>
