SRP198412 PRJNA542910 Gut microbiota plasticity is correlated with sustained weight loss on a low-carb or low-fat dietary intervention 16s rRNA sequences from fecal samples from obese participants enrolled in the DIETFITS randomized clinical trial. Participants were randomized to either a low-carbohydrate or low-fat dietary intervention for 1 year. Fecal samples were collected prior to diet initiation and after 10 weeks of dietary intervention.