SRX6384320 GSM3911542 GSM3911542: C1HTmedium_m5_1912014298_Col19_S250; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043838 GSM3911542 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911542 GEO Accession GSM3911542 SRX6384321 GSM3911543 GSM3911543: C1HTmedium_m5_1912014298_Col20_S249; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043839 GSM3911543 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911543 GEO Accession GSM3911543 SRX6384322 GSM3911544 GSM3911544: C1HTmedium_m6_1912014299_Col01_S261; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043840 GSM3911544 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911544 GEO Accession GSM3911544 SRX6384323 GSM3911545 GSM3911545: C1HTmedium_m6_1912014299_Col02_S277; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043841 GSM3911545 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911545 GEO Accession GSM3911545 SRX6384324 GSM3911546 GSM3911546: C1HTmedium_m6_1912014299_Col03_S262; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043842 GSM3911546 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911546 GEO Accession GSM3911546 SRX6384325 GSM3911547 GSM3911547: C1HTmedium_m6_1912014299_Col04_S278; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043843 GSM3911547 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911547 GEO Accession GSM3911547 SRX6384326 GSM3911548 GSM3911548: C1HTmedium_m6_1912014299_Col05_S268; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043844 GSM3911548 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911548 GEO Accession GSM3911548 SRX6384327 GSM3911549 GSM3911549: C1HTmedium_m6_1912014299_Col06_S267; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043845 GSM3911549 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911549 GEO Accession GSM3911549 SRX6384328 GSM3911550 GSM3911550: C1HTmedium_m6_1912014299_Col07_S266; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043846 GSM3911550 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911550 GEO Accession GSM3911550 SRX6384329 GSM3911551 GSM3911551: C1HTmedium_m6_1912014299_Col08_S265; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043847 GSM3911551 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911551 GEO Accession GSM3911551 SRX6384330 GSM3911552 GSM3911552: C1HTmedium_m6_1912014299_Col09_S280; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043848 GSM3911552 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911552 GEO Accession GSM3911552 SRX6384331 GSM3911553 GSM3911553: C1HTmedium_m6_1912014299_Col10_S264; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043849 GSM3911553 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911553 GEO Accession GSM3911553 SRX6384332 GSM3911554 GSM3911554: C1HTmedium_m6_1912014299_Col11_S279; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043850 GSM3911554 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911554 GEO Accession GSM3911554 SRX6384333 GSM3911555 GSM3911555: C1HTmedium_m6_1912014299_Col12_S263; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043851 GSM3911555 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911555 GEO Accession GSM3911555 SRX6384334 GSM3911556 GSM3911556: C1HTmedium_m6_1912014299_Col13_S271; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043852 GSM3911556 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911556 GEO Accession GSM3911556 SRX6384335 GSM3911557 GSM3911557: C1HTmedium_m6_1912014299_Col14_S272; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043853 GSM3911557 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911557 GEO Accession GSM3911557 SRX6384336 GSM3911444 GSM3911444: C1HTmedium_m1_1912014195_Col01_S1; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043854 GSM3911444 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911444 GEO Accession GSM3911444 SRX6384337 GSM3911445 GSM3911445: C1HTmedium_m1_1912014195_Col02_S17; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043855 GSM3911445 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911445 GEO Accession GSM3911445 SRX6384338 GSM3911558 GSM3911558: C1HTmedium_m6_1912014299_Col15_S273; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043856 GSM3911558 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911558 GEO Accession GSM3911558 SRX6384339 GSM3911559 GSM3911559: C1HTmedium_m6_1912014299_Col16_S274; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043857 GSM3911559 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911559 GEO Accession GSM3911559 SRX6384340 GSM3911560 GSM3911560: C1HTmedium_m6_1912014299_Col17_S275; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043858 GSM3911560 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911560 GEO Accession GSM3911560 SRX6384341 GSM3911561 GSM3911561: C1HTmedium_m6_1912014299_Col18_S276; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043859 GSM3911561 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911561 GEO Accession GSM3911561 SRX6384342 GSM3911562 GSM3911562: C1HTmedium_m6_1912014299_Col19_S270; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043860 GSM3911562 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911562 GEO Accession GSM3911562 SRX6384343 GSM3911563 GSM3911563: C1HTmedium_m6_1912014299_Col20_S269; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043861 GSM3911563 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911563 GEO Accession GSM3911563 SRX6384344 GSM3911564 GSM3911564: C1HTmedium_m7_1912014300_Col01_S281; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043862 GSM3911564 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911564 GEO Accession GSM3911564 SRX6384345 GSM3911565 GSM3911565: C1HTmedium_m7_1912014300_Col02_S297; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043863 GSM3911565 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911565 GEO Accession GSM3911565 SRX6384346 GSM3911566 GSM3911566: C1HTmedium_m7_1912014300_Col03_S282; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043864 GSM3911566 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911566 GEO Accession GSM3911566 SRX6384347 GSM3911567 GSM3911567: C1HTmedium_m7_1912014300_Col04_S298; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043865 GSM3911567 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911567 GEO Accession GSM3911567 SRX6384348 GSM3911568 GSM3911568: C1HTmedium_m7_1912014300_Col05_S288; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043866 GSM3911568 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911568 GEO Accession GSM3911568 SRX6384349 GSM3911569 GSM3911569: C1HTmedium_m7_1912014300_Col06_S287; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043867 GSM3911569 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911569 GEO Accession GSM3911569 SRX6384350 GSM3911570 GSM3911570: C1HTmedium_m7_1912014300_Col07_S286; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043868 GSM3911570 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911570 GEO Accession GSM3911570 SRX6384351 GSM3911571 GSM3911571: C1HTmedium_m7_1912014300_Col08_S285; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043869 GSM3911571 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911571 GEO Accession GSM3911571 SRX6384352 GSM3911572 GSM3911572: C1HTmedium_m7_1912014300_Col09_S300; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043870 GSM3911572 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911572 GEO Accession GSM3911572 SRX6384353 GSM3911573 GSM3911573: C1HTmedium_m7_1912014300_Col10_S284; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043871 GSM3911573 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911573 GEO Accession GSM3911573 SRX6384354 GSM3911574 GSM3911574: C1HTmedium_m7_1912014300_Col11_S299; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043872 GSM3911574 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911574 GEO Accession GSM3911574 SRX6384355 GSM3911575 GSM3911575: C1HTmedium_m7_1912014300_Col12_S283; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043873 GSM3911575 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911575 GEO Accession GSM3911575 SRX6384356 GSM3911576 GSM3911576: C1HTmedium_m7_1912014300_Col13_S291; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043874 GSM3911576 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911576 GEO Accession GSM3911576 SRX6384357 GSM3911577 GSM3911577: C1HTmedium_m7_1912014300_Col14_S292; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043875 GSM3911577 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911577 GEO Accession GSM3911577 SRX6384358 GSM3911578 GSM3911578: C1HTmedium_m7_1912014300_Col15_S293; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043876 GSM3911578 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911578 GEO Accession GSM3911578 SRX6384359 GSM3911579 GSM3911579: C1HTmedium_m7_1912014300_Col16_S294; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043877 GSM3911579 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911579 GEO Accession GSM3911579 SRX6384360 GSM3911580 GSM3911580: C1HTmedium_m7_1912014300_Col17_S295; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043878 GSM3911580 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911580 GEO Accession GSM3911580 SRX6384361 GSM3911581 GSM3911581: C1HTmedium_m7_1912014300_Col18_S296; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043879 GSM3911581 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911581 GEO Accession GSM3911581 SRX6384362 GSM3911582 GSM3911582: C1HTmedium_m7_1912014300_Col19_S290; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043880 GSM3911582 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911582 GEO Accession GSM3911582 SRX6384363 GSM3911583 GSM3911583: C1HTmedium_m7_1912014300_Col20_S289; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043881 GSM3911583 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911583 GEO Accession GSM3911583 SRX6384364 GSM3911446 GSM3911446: C1HTmedium_m1_1912014195_Col03_S2; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043882 GSM3911446 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911446 GEO Accession GSM3911446 SRX6384365 GSM3911447 GSM3911447: C1HTmedium_m1_1912014195_Col04_S18; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043883 GSM3911447 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911447 GEO Accession GSM3911447 SRX6384366 GSM3911448 GSM3911448: C1HTmedium_m1_1912014195_Col05_S8; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043884 GSM3911448 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911448 GEO Accession GSM3911448 SRX6384367 GSM3911449 GSM3911449: C1HTmedium_m1_1912014195_Col06_S7; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043885 GSM3911449 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911449 GEO Accession GSM3911449 SRX6384368 GSM3911450 GSM3911450: C1HTmedium_m1_1912014195_Col07_S6; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043886 GSM3911450 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911450 GEO Accession GSM3911450 SRX6384369 GSM3911451 GSM3911451: C1HTmedium_m1_1912014195_Col08_S5; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043887 GSM3911451 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911451 GEO Accession GSM3911451 SRX6384370 GSM3911452 GSM3911452: C1HTmedium_m1_1912014195_Col09_S20; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043888 GSM3911452 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911452 GEO Accession GSM3911452 SRX6384371 GSM3911453 GSM3911453: C1HTmedium_m1_1912014195_Col10_S4; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043889 GSM3911453 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911453 GEO Accession GSM3911453 SRX6384372 GSM3911454 GSM3911454: C1HTmedium_m1_1912014195_Col11_S19; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043890 GSM3911454 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911454 GEO Accession GSM3911454 SRX6384373 GSM3911455 GSM3911455: C1HTmedium_m1_1912014195_Col12_S3; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043891 GSM3911455 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911455 GEO Accession GSM3911455 SRX6384374 GSM3911456 GSM3911456: C1HTmedium_m1_1912014195_Col13_S11; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043892 GSM3911456 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911456 GEO Accession GSM3911456 SRX6384375 GSM3911457 GSM3911457: C1HTmedium_m1_1912014195_Col14_S12; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043893 GSM3911457 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911457 GEO Accession GSM3911457 SRX6384376 GSM3911458 GSM3911458: C1HTmedium_m1_1912014195_Col15_S13; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043894 GSM3911458 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911458 GEO Accession GSM3911458 SRX6384377 GSM3911459 GSM3911459: C1HTmedium_m1_1912014195_Col16_S14; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043895 GSM3911459 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911459 GEO Accession GSM3911459 SRX6384378 GSM3911460 GSM3911460: C1HTmedium_m1_1912014195_Col17_S15; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043896 GSM3911460 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911460 GEO Accession GSM3911460 SRX6384379 GSM3911461 GSM3911461: C1HTmedium_m1_1912014195_Col18_S16; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043897 GSM3911461 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911461 GEO Accession GSM3911461 SRX6384380 GSM3911462 GSM3911462: C1HTmedium_m1_1912014195_Col19_S10; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043898 GSM3911462 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911462 GEO Accession GSM3911462 SRX6384381 GSM3911463 GSM3911463: C1HTmedium_m1_1912014195_Col20_S9; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043899 GSM3911463 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911463 GEO Accession GSM3911463 SRX6384382 GSM3911464 GSM3911464: C1HTmedium_m2_1912014197_Col01_S21; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043900 GSM3911464 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911464 GEO Accession GSM3911464 SRX6384383 GSM3911465 GSM3911465: C1HTmedium_m2_1912014197_Col02_S37; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043901 GSM3911465 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911465 GEO Accession GSM3911465 SRX6384384 GSM3911466 GSM3911466: C1HTmedium_m2_1912014197_Col03_S22; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043902 GSM3911466 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911466 GEO Accession GSM3911466 SRX6384385 GSM3911467 GSM3911467: C1HTmedium_m2_1912014197_Col04_S38; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043903 GSM3911467 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911467 GEO Accession GSM3911467 SRX6384386 GSM3911468 GSM3911468: C1HTmedium_m2_1912014197_Col05_S28; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043904 GSM3911468 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911468 GEO Accession GSM3911468 SRX6384387 GSM3911469 GSM3911469: C1HTmedium_m2_1912014197_Col06_S27; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043905 GSM3911469 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911469 GEO Accession GSM3911469 SRX6384388 GSM3911470 GSM3911470: C1HTmedium_m2_1912014197_Col07_S26; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043906 GSM3911470 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911470 GEO Accession GSM3911470 SRX6384389 GSM3911471 GSM3911471: C1HTmedium_m2_1912014197_Col08_S25; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043907 GSM3911471 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911471 GEO Accession GSM3911471 SRX6384390 GSM3911472 GSM3911472: C1HTmedium_m2_1912014197_Col09_S40; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043908 GSM3911472 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911472 GEO Accession GSM3911472 SRX6384391 GSM3911473 GSM3911473: C1HTmedium_m2_1912014197_Col10_S24; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043909 GSM3911473 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911473 GEO Accession GSM3911473 SRX6384392 GSM3911474 GSM3911474: C1HTmedium_m2_1912014197_Col11_S39; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043910 GSM3911474 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911474 GEO Accession GSM3911474 SRX6384393 GSM3911475 GSM3911475: C1HTmedium_m2_1912014197_Col12_S23; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043911 GSM3911475 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911475 GEO Accession GSM3911475 SRX6384394 GSM3911476 GSM3911476: C1HTmedium_m2_1912014197_Col13_S31; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043912 GSM3911476 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911476 GEO Accession GSM3911476 SRX6384395 GSM3911477 GSM3911477: C1HTmedium_m2_1912014197_Col14_S32; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043913 GSM3911477 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911477 GEO Accession GSM3911477 SRX6384396 GSM3911478 GSM3911478: C1HTmedium_m2_1912014197_Col15_S33; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043914 GSM3911478 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911478 GEO Accession GSM3911478 SRX6384397 GSM3911479 GSM3911479: C1HTmedium_m2_1912014197_Col16_S34; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043915 GSM3911479 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911479 GEO Accession GSM3911479 SRX6384398 GSM3911480 GSM3911480: C1HTmedium_m2_1912014197_Col17_S35; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043916 GSM3911480 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911480 GEO Accession GSM3911480 SRX6384399 GSM3911481 GSM3911481: C1HTmedium_m2_1912014197_Col18_S36; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043917 GSM3911481 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911481 GEO Accession GSM3911481 SRX6384400 GSM3911482 GSM3911482: C1HTmedium_m2_1912014197_Col19_S30; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043918 GSM3911482 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911482 GEO Accession GSM3911482 SRX6384401 GSM3911483 GSM3911483: C1HTmedium_m2_1912014197_Col20_S29; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043919 GSM3911483 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911483 GEO Accession GSM3911483 SRX6384402 GSM3911484 GSM3911484: C1HTmedium_m3_1911014277_Col01_S121; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043920 GSM3911484 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911484 GEO Accession GSM3911484 SRX6384403 GSM3911485 GSM3911485: C1HTmedium_m3_1911014277_Col02_S137; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043921 GSM3911485 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911485 GEO Accession GSM3911485 SRX6384404 GSM3911486 GSM3911486: C1HTmedium_m3_1911014277_Col03_S122; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043922 GSM3911486 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911486 GEO Accession GSM3911486 SRX6384405 GSM3911487 GSM3911487: C1HTmedium_m3_1911014277_Col04_S138; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043923 GSM3911487 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911487 GEO Accession GSM3911487 SRX6384406 GSM3911488 GSM3911488: C1HTmedium_m3_1911014277_Col05_S128; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043924 GSM3911488 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911488 GEO Accession GSM3911488 SRX6384407 GSM3911489 GSM3911489: C1HTmedium_m3_1911014277_Col06_S127; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043925 GSM3911489 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911489 GEO Accession GSM3911489 SRX6384408 GSM3911490 GSM3911490: C1HTmedium_m3_1911014277_Col07_S126; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043926 GSM3911490 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911490 GEO Accession GSM3911490 SRX6384409 GSM3911491 GSM3911491: C1HTmedium_m3_1911014277_Col08_S125; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043927 GSM3911491 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911491 GEO Accession GSM3911491 SRX6384410 GSM3911492 GSM3911492: C1HTmedium_m3_1911014277_Col09_S140; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043928 GSM3911492 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911492 GEO Accession GSM3911492 SRX6384411 GSM3911493 GSM3911493: C1HTmedium_m3_1911014277_Col10_S124; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043929 GSM3911493 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911493 GEO Accession GSM3911493 SRX6384412 GSM3911494 GSM3911494: C1HTmedium_m3_1911014277_Col11_S139; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043930 GSM3911494 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911494 GEO Accession GSM3911494 SRX6384413 GSM3911495 GSM3911495: C1HTmedium_m3_1911014277_Col12_S123; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043931 GSM3911495 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911495 GEO Accession GSM3911495 SRX6384414 GSM3911496 GSM3911496: C1HTmedium_m3_1911014277_Col13_S131; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043932 GSM3911496 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911496 GEO Accession GSM3911496 SRX6384415 GSM3911497 GSM3911497: C1HTmedium_m3_1911014277_Col14_S132; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043933 GSM3911497 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911497 GEO Accession GSM3911497 SRX6384416 GSM3911498 GSM3911498: C1HTmedium_m3_1911014277_Col15_S133; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043934 GSM3911498 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911498 GEO Accession GSM3911498 SRX6384417 GSM3911499 GSM3911499: C1HTmedium_m3_1911014277_Col16_S134; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043935 GSM3911499 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911499 GEO Accession GSM3911499 SRX6384418 GSM3911500 GSM3911500: C1HTmedium_m3_1911014277_Col17_S135; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043936 GSM3911500 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911500 GEO Accession GSM3911500 SRX6384419 GSM3911501 GSM3911501: C1HTmedium_m3_1911014277_Col18_S136; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043937 GSM3911501 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911501 GEO Accession GSM3911501 SRX6384420 GSM3911502 GSM3911502: C1HTmedium_m3_1911014277_Col19_S130; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043938 GSM3911502 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911502 GEO Accession GSM3911502 SRX6384421 GSM3911503 GSM3911503: C1HTmedium_m3_1911014277_Col20_S129; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043939 GSM3911503 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911503 GEO Accession GSM3911503 SRX6384422 GSM3911504 GSM3911504: C1HTmedium_m4_1911014296_Col01_S141; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043940 GSM3911504 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911504 GEO Accession GSM3911504 SRX6384423 GSM3911505 GSM3911505: C1HTmedium_m4_1911014296_Col02_S157; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043941 GSM3911505 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911505 GEO Accession GSM3911505 SRX6384424 GSM3911506 GSM3911506: C1HTmedium_m4_1911014296_Col03_S142; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043942 GSM3911506 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911506 GEO Accession GSM3911506 SRX6384425 GSM3911507 GSM3911507: C1HTmedium_m4_1911014296_Col04_S158; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043943 GSM3911507 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911507 GEO Accession GSM3911507 SRX6384426 GSM3911508 GSM3911508: C1HTmedium_m4_1911014296_Col05_S148; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043944 GSM3911508 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911508 GEO Accession GSM3911508 SRX6384427 GSM3911509 GSM3911509: C1HTmedium_m4_1911014296_Col06_S147; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043945 GSM3911509 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911509 GEO Accession GSM3911509 SRX6384428 GSM3911510 GSM3911510: C1HTmedium_m4_1911014296_Col07_S146; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043946 GSM3911510 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911510 GEO Accession GSM3911510 SRX6384429 GSM3911511 GSM3911511: C1HTmedium_m4_1911014296_Col08_S145; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043947 GSM3911511 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911511 GEO Accession GSM3911511 SRX6384430 GSM3911512 GSM3911512: C1HTmedium_m4_1911014296_Col09_S160; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043948 GSM3911512 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911512 GEO Accession GSM3911512 SRX6384431 GSM3911513 GSM3911513: C1HTmedium_m4_1911014296_Col10_S144; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043949 GSM3911513 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911513 GEO Accession GSM3911513 SRX6384432 GSM3911514 GSM3911514: C1HTmedium_m4_1911014296_Col11_S159; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043950 GSM3911514 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911514 GEO Accession GSM3911514 SRX6384433 GSM3911515 GSM3911515: C1HTmedium_m4_1911014296_Col12_S143; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043951 GSM3911515 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911515 GEO Accession GSM3911515 SRX6384434 GSM3911516 GSM3911516: C1HTmedium_m4_1911014296_Col13_S151; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043952 GSM3911516 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911516 GEO Accession GSM3911516 SRX6384435 GSM3911517 GSM3911517: C1HTmedium_m4_1911014296_Col14_S152; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043953 GSM3911517 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911517 GEO Accession GSM3911517 SRX6384436 GSM3911518 GSM3911518: C1HTmedium_m4_1911014296_Col15_S153; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043954 GSM3911518 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911518 GEO Accession GSM3911518 SRX6384437 GSM3911519 GSM3911519: C1HTmedium_m4_1911014296_Col16_S154; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043955 GSM3911519 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911519 GEO Accession GSM3911519 SRX6384438 GSM3911520 GSM3911520: C1HTmedium_m4_1911014296_Col17_S155; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043956 GSM3911520 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911520 GEO Accession GSM3911520 SRX6384439 GSM3911521 GSM3911521: C1HTmedium_m4_1911014296_Col18_S156; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043957 GSM3911521 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911521 GEO Accession GSM3911521 SRX6384440 GSM3911522 GSM3911522: C1HTmedium_m4_1911014296_Col19_S150; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043958 GSM3911522 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911522 GEO Accession GSM3911522 SRX6384441 GSM3911523 GSM3911523: C1HTmedium_m4_1911014296_Col20_S149; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043959 GSM3911523 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911523 GEO Accession GSM3911523 SRX6384442 GSM3911524 GSM3911524: C1HTmedium_m5_1912014298_Col01_S241; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043960 GSM3911524 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911524 GEO Accession GSM3911524 SRX6384443 GSM3911525 GSM3911525: C1HTmedium_m5_1912014298_Col02_S257; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043961 GSM3911525 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911525 GEO Accession GSM3911525 SRX6384444 GSM3911526 GSM3911526: C1HTmedium_m5_1912014298_Col03_S242; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043962 GSM3911526 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911526 GEO Accession GSM3911526 SRX6384445 GSM3911527 GSM3911527: C1HTmedium_m5_1912014298_Col04_S258; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043963 GSM3911527 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911527 GEO Accession GSM3911527 SRX6384446 GSM3911528 GSM3911528: C1HTmedium_m5_1912014298_Col05_S248; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043964 GSM3911528 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911528 GEO Accession GSM3911528 SRX6384447 GSM3911529 GSM3911529: C1HTmedium_m5_1912014298_Col06_S247; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043965 GSM3911529 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911529 GEO Accession GSM3911529 SRX6384448 GSM3911530 GSM3911530: C1HTmedium_m5_1912014298_Col07_S246; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043966 GSM3911530 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911530 GEO Accession GSM3911530 SRX6384449 GSM3911531 GSM3911531: C1HTmedium_m5_1912014298_Col08_S245; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043967 GSM3911531 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911531 GEO Accession GSM3911531 SRX6384450 GSM3911532 GSM3911532: C1HTmedium_m5_1912014298_Col09_S260; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043968 GSM3911532 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911532 GEO Accession GSM3911532 SRX6384451 GSM3911533 GSM3911533: C1HTmedium_m5_1912014298_Col10_S244; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043969 GSM3911533 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911533 GEO Accession GSM3911533 SRX6384452 GSM3911534 GSM3911534: C1HTmedium_m5_1912014298_Col11_S259; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043970 GSM3911534 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911534 GEO Accession GSM3911534 SRX6384453 GSM3911535 GSM3911535: C1HTmedium_m5_1912014298_Col12_S243; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043971 GSM3911535 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911535 GEO Accession GSM3911535 SRX6384454 GSM3911536 GSM3911536: C1HTmedium_m5_1912014298_Col13_S251; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043972 GSM3911536 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911536 GEO Accession GSM3911536 SRX6384455 GSM3911537 GSM3911537: C1HTmedium_m5_1912014298_Col14_S252; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043973 GSM3911537 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911537 GEO Accession GSM3911537 SRX6384456 GSM3911538 GSM3911538: C1HTmedium_m5_1912014298_Col15_S253; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043974 GSM3911538 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911538 GEO Accession GSM3911538 SRX6384457 GSM3911539 GSM3911539: C1HTmedium_m5_1912014298_Col16_S254; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043975 GSM3911539 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911539 GEO Accession GSM3911539 SRX6384458 GSM3911540 GSM3911540: C1HTmedium_m5_1912014298_Col17_S255; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043976 GSM3911540 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911540 GEO Accession GSM3911540 SRX6384459 GSM3911541 GSM3911541: C1HTmedium_m5_1912014298_Col18_S256; Homo sapiens; Canis lupus familiaris; Mus musculus; RNA-Seq SRP212639 SRS5043977 GSM3911541 RNA-Seq TRANSCRIPTOMIC cDNA PBMCs were isolated according to the manufacturer's instructions for FICOLL extraction (pluriSelect).Minced mouse colon was digested in 1X HBSS and 83 µl of collagenase IV (final concentration 166 U/ml) for 15 min at 37ºC and filtered through a 70 µm nylon mesh. Sequencing librraries were prepared according to the respective single-cell RNA-seq protocols as detailed in the Methods and referenced in TableS1. Library selection and sequencing was performed following recommendations of to the respective single-cell RNA-seq protocols as detailed in the Methods. Illumina NovaSeq 6000 gds 303911541 GEO Accession GSM3911541