SRX6479865 HSA_LR_CNTL_4 SRP215318 PRJNA555349 RNA was TRIZol extracted from quadriceps muscle of HSALR mice treated with Corn oil. RNA quality was checked and the NEBNext Ultra II Directional RNA Library Prep Kit for Illumina with NEBNext rRNA Depletion Kit was used to prepare RNA-seq libraries, with a total of 500 ng input RNA from each sample. The manufacturers protocols were followed, with the following exceptions: 40X adaptor dilutions used, all bead incubations done at room temp, used 4X lower concentrations of index primers, and ten cycles of library amplification were performed. The resulting libraries were pooled in equimolar amounts, quantified using the KAPA Library Quant Kit for Illumina, quality checked, and were sequenced using paired-end, 75 base pair sequencing on the Illumina NextSeq 500 massively parallel sequencer at the University of Florida Center for NeuroGenetics. SRS5128494 SAMN12325319 HSA_LR_CNTL_4 RNA-Seq TRANSCRIPTOMIC cDNA NextSeq 500 SRX6479866 HSA_LR_10_PaF_4 SRP215318 PRJNA555349 RNA was TRIZol extracted from quadriceps muscle of HSALR mice treated with 10mg/kg pafuramidine in Corn oil. RNA quality was checked and the NEBNext Ultra II Directional RNA Library Prep Kit for Illumina with NEBNext rRNA Depletion Kit was used to prepare RNA-seq libraries, with a total of 500 ng input RNA from each sample. The manufacturers protocols were followed, with the following exceptions: 40X adaptor dilutions used, all bead incubations done at room temp, used 4X lower concentrations of index primers, and ten cycles of library amplification were performed. The resulting libraries were pooled in equimolar amounts, quantified using the KAPA Library Quant Kit for Illumina, quality checked, and were sequenced using paired-end, 75 base pair sequencing on the Illumina NextSeq 500 massively parallel sequencer at the University of Florida Center for NeuroGenetics. SRS5128490 SAMN12325325 HSA_LR_10_PaF_4 RNA-Seq TRANSCRIPTOMIC cDNA NextSeq 500 SRX6479867 HSA_LR_EM_PaF_2 SRP215318 PRJNA555349 RNA was TRIZol extracted from quadriceps muscle of HSALR mice treated with 600 mg/kg erythromycin and 10mg/kg pafuramidine in Corn oil. RNA quality was checked and the NEBNext Ultra II Directional RNA Library Prep Kit for Illumina with NEBNext rRNA Depletion Kit was used to prepare RNA-seq libraries, with a total of 500 ng input RNA from each sample. The manufacturers protocols were followed, with the following exceptions: 40X adaptor dilutions used, all bead incubations done at room temp, used 4X lower concentrations of index primers, and ten cycles of library amplification were performed. The resulting libraries were pooled in equimolar amounts, quantified using the KAPA Library Quant Kit for Illumina, quality checked, and were sequenced using paired-end, 75 base pair sequencing on the Illumina NextSeq 500 massively parallel sequencer at the University of Florida Center for NeuroGenetics. SRS5128491 SAMN12325326 HSA_LR_EM_PaF_2 RNA-Seq TRANSCRIPTOMIC cDNA NextSeq 500 SRX6479868 HSA_LR_600_EM_1 SRP215318 PRJNA555349 RNA was TRIZol extracted from quadriceps muscle of HSALR mice treated with 600mg/kg erythromycin in Corn oil. RNA quality was checked and the NEBNext Ultra II Directional RNA Library Prep Kit for Illumina with NEBNext rRNA Depletion Kit was used to prepare RNA-seq libraries, with a total of 500 ng input RNA from each sample. The manufacturers protocols were followed, with the following exceptions: 40X adaptor dilutions used, all bead incubations done at room temp, used 4X lower concentrations of index primers, and ten cycles of library amplification were performed. The resulting libraries were pooled in equimolar amounts, quantified using the KAPA Library Quant Kit for Illumina, quality checked, and were sequenced using paired-end, 75 base pair sequencing on the Illumina NextSeq 500 massively parallel sequencer at the University of Florida Center for NeuroGenetics. SRS5128495 SAMN12325320 HSA_LR_600_EM_1 RNA-Seq TRANSCRIPTOMIC cDNA NextSeq 500 SRX6479869 HSA_LR_EM_PaF_3 SRP215318 PRJNA555349 RNA was TRIZol extracted from quadriceps muscle of HSALR mice treated with 600 mg/kg erythromycin and 10mg/kg pafuramidine in Corn oil. RNA quality was checked and the NEBNext Ultra II Directional RNA Library Prep Kit for Illumina with NEBNext rRNA Depletion Kit was used to prepare RNA-seq libraries, with a total of 500 ng input RNA from each sample. The manufacturers protocols were followed, with the following exceptions: 40X adaptor dilutions used, all bead incubations done at room temp, used 4X lower concentrations of index primers, and ten cycles of library amplification were performed. The resulting libraries were pooled in equimolar amounts, quantified using the KAPA Library Quant Kit for Illumina, quality checked, and were sequenced using paired-end, 75 base pair sequencing on the Illumina NextSeq 500 massively parallel sequencer at the University of Florida Center for NeuroGenetics. SRS5128500 SAMN12325327 HSA_LR_EM_PaF_3 RNA-Seq TRANSCRIPTOMIC cDNA NextSeq 500 SRX6479870 HSA_LR_EM_PaF_4 SRP215318 PRJNA555349 RNA was TRIZol extracted from quadriceps muscle of HSALR mice treated with 600 mg/kg erythromycin and 10mg/kg pafuramidine in Corn oil. RNA quality was checked and the NEBNext Ultra II Directional RNA Library Prep Kit for Illumina with NEBNext rRNA Depletion Kit was used to prepare RNA-seq libraries, with a total of 500 ng input RNA from each sample. The manufacturers protocols were followed, with the following exceptions: 40X adaptor dilutions used, all bead incubations done at room temp, used 4X lower concentrations of index primers, and ten cycles of library amplification were performed. The resulting libraries were pooled in equimolar amounts, quantified using the KAPA Library Quant Kit for Illumina, quality checked, and were sequenced using paired-end, 75 base pair sequencing on the Illumina NextSeq 500 massively parallel sequencer at the University of Florida Center for NeuroGenetics. SRS5128501 SAMN12325328 HSA_LR_EM_PaF_4 RNA-Seq TRANSCRIPTOMIC cDNA NextSeq 500 SRX6479871 HSA_LR_CNTL_2 SRP215318 PRJNA555349 RNA was TRIZol extracted from quadriceps muscle of HSALR mice treated with Corn oil. RNA quality was checked and the NEBNext Ultra II Directional RNA Library Prep Kit for Illumina with NEBNext rRNA Depletion Kit was used to prepare RNA-seq libraries, with a total of 500 ng input RNA from each sample. The manufacturers protocols were followed, with the following exceptions: 40X adaptor dilutions used, all bead incubations done at room temp, used 4X lower concentrations of index primers, and ten cycles of library amplification were performed. The resulting libraries were pooled in equimolar amounts, quantified using the KAPA Library Quant Kit for Illumina, quality checked, and were sequenced using paired-end, 75 base pair sequencing on the Illumina NextSeq 500 massively parallel sequencer at the University of Florida Center for NeuroGenetics. SRS5128492 SAMN12325317 HSA_LR_CNTL_2 RNA-Seq TRANSCRIPTOMIC cDNA NextSeq 500 SRX6479872 HSA_LR_CNTL_3 SRP215318 PRJNA555349 RNA was TRIZol extracted from quadriceps muscle of HSALR mice treated with Corn oil. RNA quality was checked and the NEBNext Ultra II Directional RNA Library Prep Kit for Illumina with NEBNext rRNA Depletion Kit was used to prepare RNA-seq libraries, with a total of 500 ng input RNA from each sample. The manufacturers protocols were followed, with the following exceptions: 40X adaptor dilutions used, all bead incubations done at room temp, used 4X lower concentrations of index primers, and ten cycles of library amplification were performed. The resulting libraries were pooled in equimolar amounts, quantified using the KAPA Library Quant Kit for Illumina, quality checked, and were sequenced using paired-end, 75 base pair sequencing on the Illumina NextSeq 500 massively parallel sequencer at the University of Florida Center for NeuroGenetics. SRS5128493 SAMN12325318 HSA_LR_CNTL_3 RNA-Seq TRANSCRIPTOMIC cDNA NextSeq 500 SRX6479873 HSA_LR_10_PaF_1 SRP215318 PRJNA555349 RNA was TRIZol extracted from quadriceps muscle of HSALR mice treated with 10mg/kg pafuramidine in Corn oil. RNA quality was checked and the NEBNext Ultra II Directional RNA Library Prep Kit for Illumina with NEBNext rRNA Depletion Kit was used to prepare RNA-seq libraries, with a total of 500 ng input RNA from each sample. The manufacturers protocols were followed, with the following exceptions: 40X adaptor dilutions used, all bead incubations done at room temp, used 4X lower concentrations of index primers, and ten cycles of library amplification were performed. The resulting libraries were pooled in equimolar amounts, quantified using the KAPA Library Quant Kit for Illumina, quality checked, and were sequenced using paired-end, 75 base pair sequencing on the Illumina NextSeq 500 massively parallel sequencer at the University of Florida Center for NeuroGenetics. SRS5128498 SAMN12325323 HSA_LR_10_PaF_1 RNA-Seq TRANSCRIPTOMIC cDNA NextSeq 500 SRX6479874 HSA_LR_10_PaF_3 SRP215318 PRJNA555349 RNA was TRIZol extracted from quadriceps muscle of HSALR mice treated with 10mg/kg pafuramidine in Corn oil. RNA quality was checked and the NEBNext Ultra II Directional RNA Library Prep Kit for Illumina with NEBNext rRNA Depletion Kit was used to prepare RNA-seq libraries, with a total of 500 ng input RNA from each sample. The manufacturers protocols were followed, with the following exceptions: 40X adaptor dilutions used, all bead incubations done at room temp, used 4X lower concentrations of index primers, and ten cycles of library amplification were performed. The resulting libraries were pooled in equimolar amounts, quantified using the KAPA Library Quant Kit for Illumina, quality checked, and were sequenced using paired-end, 75 base pair sequencing on the Illumina NextSeq 500 massively parallel sequencer at the University of Florida Center for NeuroGenetics. SRS5128499 SAMN12325324 HSA_LR_10_PaF_3 RNA-Seq TRANSCRIPTOMIC cDNA NextSeq 500 SRX6479875 HSA_LR_600_EM_2 SRP215318 PRJNA555349 RNA was TRIZol extracted from quadriceps muscle of HSALR mice treated with 600mg/kg erythromycin in Corn oil. RNA quality was checked and the NEBNext Ultra II Directional RNA Library Prep Kit for Illumina with NEBNext rRNA Depletion Kit was used to prepare RNA-seq libraries, with a total of 500 ng input RNA from each sample. The manufacturers protocols were followed, with the following exceptions: 40X adaptor dilutions used, all bead incubations done at room temp, used 4X lower concentrations of index primers, and ten cycles of library amplification were performed. The resulting libraries were pooled in equimolar amounts, quantified using the KAPA Library Quant Kit for Illumina, quality checked, and were sequenced using paired-end, 75 base pair sequencing on the Illumina NextSeq 500 massively parallel sequencer at the University of Florida Center for NeuroGenetics. SRS5128496 SAMN12325321 HSA_LR_600_EM_2 RNA-Seq TRANSCRIPTOMIC cDNA NextSeq 500 SRX6479876 HSA_LR_600_EM_4 SRP215318 PRJNA555349 RNA was TRIZol extracted from quadriceps muscle of HSALR mice treated with 600mg/kg erythromycin in Corn oil. RNA quality was checked and the NEBNext Ultra II Directional RNA Library Prep Kit for Illumina with NEBNext rRNA Depletion Kit was used to prepare RNA-seq libraries, with a total of 500 ng input RNA from each sample. The manufacturers protocols were followed, with the following exceptions: 40X adaptor dilutions used, all bead incubations done at room temp, used 4X lower concentrations of index primers, and ten cycles of library amplification were performed. The resulting libraries were pooled in equimolar amounts, quantified using the KAPA Library Quant Kit for Illumina, quality checked, and were sequenced using paired-end, 75 base pair sequencing on the Illumina NextSeq 500 massively parallel sequencer at the University of Florida Center for NeuroGenetics. SRS5128497 SAMN12325322 HSA_LR_600_EM_4 RNA-Seq TRANSCRIPTOMIC cDNA NextSeq 500