SRP220524 PRJNA564135 GSE136975 Modulating the unfolded protein response: Impacts of radiation on the response of prostate cancer cells to ONC201. RNA-Seq analysis of prostate cancer cells primed to irradiation for 24hours with ONC201 shows a sustained suppression of transcripts encoding cell cycle regulators as well as components of the DNA damage response pathways. Overall design: Evaluation of ONC201 as radio-sensitizer in prostate cancer samples. GSE136975