<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY center_name="GEO" alias="GSE137819" accession="SRP222892">
    <IDENTIFIERS>
      <PRIMARY_ID>SRP222892</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA573523</EXTERNAL_ID>
      <EXTERNAL_ID namespace="GEO">GSE137819</EXTERNAL_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>Migratory and Dancing Macrophage Subsets in Atherosclerotic Lesions</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Transcriptome Analysis"/>
      <STUDY_ABSTRACT>Macrophage heterogeneity within atherosclerotic plaques was explored with intravital imaging, flow cytometry, and RNA sequencing. 4 populations of cells were found with varying expression profiles and functions relevant to atherosclerosis and inflammation. Overall design: Cells were sorted from the aortas and carotid arteries of atherosclerotic Apoe-/- Cx3cr1GFP Cd11cYFP mice fed Western Diet based on GFP and YFP expression. The expression profiles of the 4 subsets (GFP+, GFP+YFP+, YFP+, GFP-YFP-) were found using an Illumina HiSeq4000.</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>GSE137819</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
    <STUDY_LINKS>
      <STUDY_LINK>
        <XREF_LINK>
          <DB>pubmed</DB>
          <ID>31594470</ID>
        </XREF_LINK>
      </STUDY_LINK>
    </STUDY_LINKS>
  </STUDY>
</STUDY_SET>
