SRP223001 PRJNA573703 GSE137873 Day23_exon3lines Haploinsufficiency of transcriptional regulators causes human congenital heart disease (CHD), predicting gene regulatory network (GRN) imbalances. Here, we define transcriptional responses to reduced transcription factor dosage in human iPSCs heterozygous or homozygous for loss of the CHD gene TBX5. Overall design: Single cell RNA sequencing of day 23 cells from exon3 lines (WTC11, Control, TBX5Het and TBX5Hom) in duplicate GSE137873 pubmed 33321106 parent_bioproject PRJNA573698