<?xml version="1.0" encoding="UTF-8"?>
<STUDY_SET xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <STUDY center_name="GEO" alias="GSE140663" accession="SRP230621">
    <IDENTIFIERS>
      <PRIMARY_ID>SRP230621</PRIMARY_ID>
      <EXTERNAL_ID namespace="BioProject" label="primary">PRJNA590481</EXTERNAL_ID>
      <EXTERNAL_ID namespace="GEO">GSE140663</EXTERNAL_ID>
    </IDENTIFIERS>
    <DESCRIPTOR>
      <STUDY_TITLE>Drosophila Exhibit Divergent Sex-Based Responses in Transcription and Motor Function After Traumatic Brain Injury</STUDY_TITLE>
      <STUDY_TYPE existing_study_type="Transcriptome Analysis"/>
      <STUDY_ABSTRACT>Adult male and female w1118 flies were inflicted with traumatic brain injury using high-impact trauma device. Brains were dissected at control, 1, 2 and 4 hours post-TBI. Total RNA was extracted from fly brains and 3'mRNA-seq was performed to assess gene expression changes in response to TBI in both sexes. 3 replicates were sequenced for each condition. Overall design: To investigate sex-differences in gene expression at control, 1, 2 and 4-hours post-TBI in Drosophila</STUDY_ABSTRACT>
      <CENTER_PROJECT_NAME>GSE140663</CENTER_PROJECT_NAME>
    </DESCRIPTOR>
    <STUDY_LINKS>
      <STUDY_LINK>
        <XREF_LINK>
          <DB>pubmed</DB>
          <ID>32636795</ID>
        </XREF_LINK>
      </STUDY_LINK>
      <STUDY_LINK>
        <XREF_LINK>
          <DB>pubmed</DB>
          <ID>33790803</ID>
        </XREF_LINK>
      </STUDY_LINK>
    </STUDY_LINKS>
  </STUDY>
</STUDY_SET>
