LOCUS       KCVO01000001             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:19645:16564
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000001
VERSION     KCVO01000001.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19645:16564"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72030.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          157 c          129 g          110 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcactggga gcagttccaa cattggaggt tattatgtgc agtggtacca gcagcttcca
      241 ggaacggccc ccaaactcct catgtatgaa aataataagc gaccctcagg ggtttctgat
      301 cgattctctg gctcccagtc tggtacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gcctgagtgc cgtgttattc
      421 ggagcaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01000002             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:21528:4237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000002
VERSION     KCVO01000002.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:21528:4237"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..441
                     /note="immunoglobulin light chain variable region"
     V_region        111..441
     V_segment       111..403
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72031.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       405..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           89 a          156 c          127 g          107 t
ORIGIN      
        1 acatggggct tcagctgtgg gcacaggagg cagcactcag gacagtctcc agcatggcct
       61 ggtctcctct cctcctcacc cttctcattc actgcacagg gtcctgggcc cagtctgtgc
      121 tgacgcagcc gccctcagtg tctggggcgc ccgggcagag ggtcaccatc ccctgcactg
      181 ggagcagttc caacattgga ggttattatg tgcagtggta ccagcagctt ccaggaacgg
      241 cccccaaact cctcatgtat gaaaataata agcgaccctc aggggtttct gatcgattct
      301 ctggctccca gtctggtacc tcagcctccc tgaccatcac tggactccag tctgaggatg
      361 aggctgatta ttactgccag tcctatgaca gcagcctgag tgccgtgtta ttcggagcag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000003             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:14949:22455
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000003
VERSION     KCVO01000003.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14949:22455"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..449
                     /note="immunoglobulin light chain variable region"
     V_region        116..449
     V_segment       116..409
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72032.1"
                     /translation="DYFCSVWDSSLSSYIF"
     J_segment       412..449
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           91 a          159 c          126 g          111 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctctccttc tcactctgct ggttcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagcatctgg ggcccccggg cagagggtca ccatctcctg
      181 cactgggagc agctccaaca tcggggcggc ttattctgta tcctggtacc agcagttccc
      241 aggaacagcc cccaaactcc tcatctatga aaataataag cgaccctcag gggtttctga
      301 ccgattctct ggctccaagt ctggtacctc agcctccctg accatcactg gactccaatc
      361 tgaggatgag gctgattatt tctgctcagt ctgggatagc agcctgagta gttacatctt
      421 cggtgctggg acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct
      481 gttcccg
//
LOCUS       KCVO01000004             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:10430:6514
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000004
VERSION     KCVO01000004.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10430:6514"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72033.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           97 a          144 c          120 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagacaaa tatgcttatt ggtaccggca gaaaccaggc cagtccccta tactgatcat
      241 ctatgaagac aacaaacggc cctctgggat ccctgaaaga ttctctggct ccagttcagg
      301 gacagtggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 ttactctgca gacaacagtg gtcagggctc attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000005             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:10051:13532
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000005
VERSION     KCVO01000005.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10051:13532"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..454
                     /note="immunoglobulin light chain variable region"
     V_region        130..454
     V_segment       130..417
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72034.1"
                     /translation="DYYCYSTDTSGNHRLF"
     J_segment       420..454
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT          103 a          149 c          134 g          106 t
ORIGIN      
        1 acatggggaa gagaagccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactccccc tcctcacttt ctgcacaggc
      121 tctgcagcct cctatgagct gacacagcca ccctcggtgt cagtgtcccc aggacagacg
      181 gccaggatca cctgctctgg agatgcattg ccaaaaaaat atgcttattg gttccagcag
      241 aagccaggcc agtcccctgt gctgatcatc tatggggaca tcaaacggcc ctctgggatc
      301 cctgagagat tctctggctc cagctcaggg acagtggcca ccttgactat cagtggggcc
      361 caggtggagg atgaagctga ctactactgt tactcaacag ataccagtgg taatcatagg
      421 ttattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      481 actctcttcc cg
//
LOCUS       KCVO01000006             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:20397:10687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000006
VERSION     KCVO01000006.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20397:10687"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72035.1"
                     /translation="DYYCCSYAGRFTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           80 a          157 c          124 g          114 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcagcctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactgggac
      181 cagcagtgac atcggtgatt atgactttgt ctcctggtac caacagcatc caggcacagc
      241 ccccaaactc ataatttttg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tccggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 cgctgattat tactgctgct catatgcagg caggttcact tttgtgttcg gaagtggcac
      421 cagtttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01000007             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:22206:12500
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000007
VERSION     KCVO01000007.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22206:12500"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72036.1"
                     /translation="DYYCHLYDTTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          163 c          122 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcact tgtatgacac tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000008             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:11769:11683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000008
VERSION     KCVO01000008.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:11769:11683"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..429
                     /note="immunoglobulin light chain variable region"
     V_region        106..429
     V_segment       106..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72037.1"
                     /translation="DYYCQVWDSSSDHCLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          143 c          142 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtcccctat gcgctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaag tgactatgtg cactggtacc aacagaaggc agcgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000009             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:20182:9883
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000009
VERSION     KCVO01000009.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20182:9883"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..450
                     /note="immunoglobulin light chain variable region"
     V_region        117..450
     V_segment       117..410
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72038.1"
                     /translation="DYYCLSYDNSLSAHYIF"
     J_segment       413..450
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           94 a          164 c          120 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctcgtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac acagccaccc tcagtgtctg gggccccagg gcagagggtc accatctcgt
      181 gcactgggag cagctccagc attggaggtg attatgtgtc ctggtaccaa caggtcccag
      241 gaacgacccc caaactcctc atctatcaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagactg
      361 aggatgaggc tgattactac tgcctgtcct atgacaacag tctgagtgct cattacatct
      421 tcggtcctgg gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc
      481 tgttcccg
//
LOCUS       KCVO01000010             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:11733:7990
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000010
VERSION     KCVO01000010.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11733:7990"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..306
                     /note="immunoglobulin light chain variable region"
     V_region        87..306
     V_segment       87..267
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72039.1"
                     /translation="DYYCYSIDSNTYLGFF"
     J_segment       269..306
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           67 a          108 c           91 g           78 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagc agaagccagg ccagtcccct gtactgatca
      121 tctatgagga caccaaacgg ccctctggga tccctgagag attctctggc tccagctcag
      181 ggacagtggc caccttgact atcagtgggg cccaggtgga ggatgaagct gactactact
      241 gttactcaat agatagcaat acttatcttg gcttcttcgg aggagggacc cggctgaccg
      301 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000011             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:19547:12608
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000011
VERSION     KCVO01000011.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:19547:12608"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72040.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          161 c          126 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcggaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000012             306 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:9680:15865
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000012
VERSION     KCVO01000012.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 306)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9680:15865"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..268
                     /note="immunoglobulin light chain variable region"
     V_region        8..268
     V_segment       8..231
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <193..>240
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72041.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       238..268
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        269..>306
                     /gene="IGLC"
BASE COUNT           66 a           87 c           89 g           64 t
ORIGIN      
        1 acatggggtg ggggagacaa ccttggagat aaatatctac actggtacca ccagaagcca
       61 gcgcaggccc ctgtgctggt catctactat gatagtgacc ggccctcatg gatccctgag
      121 cgattctctg ggtccaagtc agggaacacc gccaccctga ccatcagcgg ggtcgaggcc
      181 ggggatgagg ctgactatta ctgtcaggtg tgggacagta ataatgatca tattttcttc
      241 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      301 ttcccg
//
LOCUS       KCVO01000013             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:12505:10480
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000013
VERSION     KCVO01000013.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12505:10480"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..402
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72042.1"
                     /translation="DYYCGSYRTGNTLLF"
     J_segment       403..435
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           82 a          155 c          126 g          112 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcgggac gtctccacca tggcttgggc
       61 tctggtcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtccgtc accatctcct gcagtggaag
      181 cagcagtgac attggtggtt ttaacggtgt ctcctggtac cagcagcact caggcacagc
      241 ccccagactc ctgatttatg aggtcagtaa gaggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctgccaaca cggcctccct gaccatctct gggctccagg ctgacgatga
      361 ggctgactat tactgcggct catataggac tggaaatact ttgttattcg gttcagggac
      421 ccggctgacc gtcctgggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000014             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:3706:19679
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000014
VERSION     KCVO01000014.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:3706:19679"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72043.1"
                     /translation="DYYCYSTDSSGNHWVF"
     J_segment       375..411
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           91 a          141 c          118 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcccca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tacattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagata
      361 gcagtggtaa tcattgggtg ttcggcggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000015             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:24243:5417
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000015
VERSION     KCVO01000015.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:24243:5417"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72044.1"
                     /translation="DYYCSSYSSSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          156 c          123 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctcc gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat actcaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000016             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:11064:14409
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000016
VERSION     KCVO01000016.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:11064:14409"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72045.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       396..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          146 c          133 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgag ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaacc
      181 ttggagataa atatctacac tggtaccacc agaagccagc gcaggcccct gtgctggtca
      241 tctactatga tagtgaccgg ccctcatgga tccctgagcg attctctggg tccaagtcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtaat aatgatcata tctttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000017             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:21903:16738
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000017
VERSION     KCVO01000017.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:21903:16738"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72046.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          155 c          123 g          108 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca gtagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000018             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:21042:19234
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000018
VERSION     KCVO01000018.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:21042:19234"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..385
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72047.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       388..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           85 a          141 c          140 g           97 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactgcac agactctgtg gtctcctatg aattgactca
      121 gccacgctca gtgtccgtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt agaagtgtgc agtggtacca gcagaagcca ccgcagggcc ttctactggt
      241 catctattct gatagcgaac ggccctcagg gatccctggg cgattctctg gctccaattt
      301 agggaacacc gccaccctga ccatcagcgg cgtcgaggcc ggggatgggg ctgactatta
      361 ctgtcaggtg tgggacagta gtagtgatgt gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000019             333 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:15159:11775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000019
VERSION     KCVO01000019.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 333)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:15159:11775"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    163..293
                     /note="immunoglobulin light chain variable region"
     V_region        163..293
     V_segment       163..259
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <223..>267
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72048.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       260..293
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        294..>333
                     /gene="IGLC"
BASE COUNT           55 a          115 c           89 g           74 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcactct caggacgtct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 tctccctctg tgtctgggtc tcctggacag tcggtcacca tttccaagtc tggcaacacg
      181 gcctccctga tcatctctgg gctccaggct gaggacgagg ctgattatta ctgcagctca
      241 tacacaagca gtagcacttg ggtattcggc ggagggaccc ggctgaccgt ccttggtcag
      301 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000020             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:11551:14258
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000020
VERSION     KCVO01000020.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11551:14258"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..432
                     /note="immunoglobulin light chain variable region"
     V_region        105..432
     V_segment       105..388
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72049.1"
                     /translation="DYYCSSYAGTNRVF"
     J_segment       397..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           84 a          156 c          124 g          106 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcaggactt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agcctccctc tgtgtccggg tctcctggac agtcggtcac cctctcctgc actggaacca
      181 gcagtgatat tgggtatttt aatgctgtgt cttggtacca acaacatcca ggcaaggccc
      241 ccaaactcat gatttatgag gtcaataagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggca ccaacagggt gttcggcgga gggacccgcc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000021             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:4534:9122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000021
VERSION     KCVO01000021.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4534:9122"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72050.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       412..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          156 c          129 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gttctgactc agcctccctc ggcgtctgag gccgccggga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagtaac agtgtgtcct ggtacctgca gctcccagaa
      241 acggctccca aactcctcat ctattataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cccgtcagcc tccctggcca tcagtgggct cgagaccgaa
      361 gatgaggctg attattactg cgcagtctgg gatgatagcc tgagcggtgt attattcggg
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01000022             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:8515:12119
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000022
VERSION     KCVO01000022.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:8515:12119"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72051.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          142 c          139 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagtc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gtgggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga acgattctct ggctccaaat
      301 cagggagcgc cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000023             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:9824:10710
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000023
VERSION     KCVO01000023.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9824:10710"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72052.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           92 a          142 c          125 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca caagccaggc cagtcccctg tgctgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc acattgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagtagtg gtaattatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000024             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:19850:9477
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000024
VERSION     KCVO01000024.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:19850:9477"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..427
                     /note="immunoglobulin light chain variable region"
     V_region        105..427
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72053.1"
                     /translation="DYYCQVWDSSSDHWVF"
     J_segment       392..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>467
                     /gene="IGLC"
BASE COUNT           85 a          147 c          141 g           94 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca caggctctgc ggtctcctat gagctgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggcccg gatcacctgt gggggagaca
      181 acattggaag taaaagtgtg cagtggttcc agcagaagcc accgcaggcc cctgtgctgg
      241 tcatttatgg tgatatcgaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cgggaatgag gctgactatt
      361 actgtcaggt atgggacagt agtagtgatc attgggtatt cggcggaggg acccggctga
      421 ccgtcctcgg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000025             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:10028:9707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000025
VERSION     KCVO01000025.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10028:9707"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..434
                     /note="immunoglobulin light chain variable region"
     V_region        90..434
     V_segment       90..399
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72054.1"
                     /translation="DYYCLIWHNNVWVF"
     J_segment       400..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>473
                     /gene="IGLC"
BASE COUNT           93 a          153 c          113 g          114 t
ORIGIN      
        1 acatgggggc agggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcgc agcctgcgct gactcagcca acctccctct
      121 cagcatctcc tggagcatca gccagattca cctgcacctt gagcagaggc atcagtgttg
      181 ctatttatag gatattctgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 actcccacac agactcagat aaacaccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcagggattt tactcatctc tggcctccag tctgaggatg
      361 aggctgacta ttactgtttg atttggcaca acaatgtttg ggttttcggc ggagggaccc
      421 ggctgaccgt cctaagtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000026             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:21687:15019
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000026
VERSION     KCVO01000026.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:21687:15019"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72055.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           83 a          158 c          121 g          113 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggcactt ataactatgt ctcctggtac caacaacatc caggcacagc
      241 ccccacactc atgatttttg aggtcagtga gcggccctca ggggtctctg atcggttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgttgct catatgcaga cacctacact tttgtgtttg gaggtggcac
      421 cagattgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01000027             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:15748:6766
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000027
VERSION     KCVO01000027.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15748:6766"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72056.1"
                     /translation="DYYCQVWDITTDHDVF"
     J_segment       390..426
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           94 a          137 c          131 g          102 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatgacc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gttctgcggc ctcctatgag ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacgaca
      181 ttggaagtaa aaatgttcac tggtaccagc agaagccacc gcaggcccct gtattggtca
      241 tctattatga tagcaaacgg ccctcaggga tccctgagcg attctctggc gccaaatcag
      301 ggaacaccgc caccctgatc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacattact actgatcatg atgtgttcgg aagtggcacc aagttgaccg
      421 tcctcggtca gcccaaggct tcccccttgg tcactctgtt cccg
//
LOCUS       KCVO01000028             354 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:5170:16767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000028
VERSION     KCVO01000028.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 354)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 354)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..354
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5170:16767"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..316
                     /note="immunoglobulin light chain variable region"
     V_region        8..316
     V_segment       8..279
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <241..>288
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72057.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       284..316
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        317..>354
                     /gene="IGLC"
BASE COUNT           76 a           99 c          109 g           70 t
ORIGIN      
        1 acatgggagc caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg
       61 ggagacaatg ttggaagtga atatgtgcac tggtaccaac agaaaccagc gcaggcccct
      121 gtggtggtca tccattataa tagtgaccgg ccctcaggga tccctgagcg attctctggc
      181 tccaaatcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct
      241 gactattact gtcaggtgtg ggacagtagt agtgatcatt gtgtattggg aggagggacc
      301 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000029             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:10280:9198
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000029
VERSION     KCVO01000029.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:10280:9198"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72058.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           83 a          151 c          124 g          115 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggtttt gagtgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactctt gatttatgag gtcagttatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tgccaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ttgcagctca tacacaagta gtagtacttg ggtattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000030             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:9580:8546
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000030
VERSION     KCVO01000030.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9580:8546"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..388
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72059.1"
                     /translation="DYYCLLYYSGVWVF"
     J_segment       390..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           94 a          150 c          121 g          100 t
ORIGIN      
        1 acatgggggg agccagagat cccttccaat accagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gacgcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtggctc cagcactgga
      181 gcagtcacca gtggtaacta tccaaactgg ttccagcaga aacctggaca agtccccagg
      241 ggactgattt acaatacaaa cagccaacac tcctggaccc ctgcccggtt ctcaggctcc
      301 ctcgctgggg gcaaagctgc cctgacactg tcaggtgcac agcccgagga cgaggctgat
      361 tattactgtt tgttgtacta tagtggtgtt tgggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000031             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:14240:13246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000031
VERSION     KCVO01000031.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14240:13246"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72060.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           94 a          145 c          122 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctctgacc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaatac tatgcttatt ggttccagca gaagccaggc cagtcccctg tggcgatcat
      241 ctatgaggac aacaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtgtggc ccaggtagag gatgaagctg actactactg
      361 ttactcaaca gatagcagtg gtactaatgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000032             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:20904:5038
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000032
VERSION     KCVO01000032.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20904:5038"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72061.1"
                     /translation="DYHCFSTDSSGNQRGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           94 a          142 c          126 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgacgac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcattggggc ccaggtggag gatgaaggtg actaccactg
      361 tttctcaaca gatagtagtg gtaatcaaag gggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000033             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:12073:10069
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000033
VERSION     KCVO01000033.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12073:10069"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..412
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72062.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       413..449
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           97 a          161 c          122 g          107 t
ORIGIN      
        1 acatggggaa gcgcagcttc agctgtgggt acagaaggca ggactcagga caatctccag
       61 catggcctgg ttccctctcc tcctcaccct cctcactcac tgtgcagggt cctgggccca
      121 gtctgtgctg actcagcctc cctcagcgtc tgaggccgcc aggaagagtg tcaccatctc
      181 ctgttctgga agcacctcca acatcggaac taatagtgta tcctggtacc agcagctccc
      241 agaaacggct cccaaactcc tcatctatta taatgatcga cgagcctcag gtgtctctga
      301 ccgattctct ggctccaagt ctggcacgtc agcctccctg gccatcagtg ggctccagac
      361 cgaggatgag gctgattatt actgcgcagc atgggataac agcctgagcg gttacatctt
      421 cggtgctggg acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct
      481 gttcccg
//
LOCUS       KCVO01000034             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:15908:15757
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000034
VERSION     KCVO01000034.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:15908:15757"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..265
                     /note="immunoglobulin light chain variable region"
     V_region        1..265
     V_segment       1..228
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>237
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72063.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       233..265
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        266..>303
                     /gene="IGLC"
BASE COUNT           67 a           84 c           83 g           69 t
ORIGIN      
        1 acatgggctg gagatgcatt gccaaaaaag tatgcttatt ggttccagca gaagccaggc
       61 cagtcccctg tgctgatcat ctatgaagac gacaaacggc cctctgggat ccctgagaga
      121 ttctctggct ccagctcagg gacagtggcc accttgacta tcagtggggc ccaggtggag
      181 gatgaagctg actactactg ttactcaata gatagtagtg gtagtcatag cgtcttcggt
      241 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      301 ccg
//
LOCUS       KCVO01000035             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:9493:13368
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000035
VERSION     KCVO01000035.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:9493:13368"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72064.1"
                     /translation="DYYCYSTDSSDNHSIF"
     J_segment       377..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           96 a          138 c          112 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgat gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ttcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttat tcaacagata
      361 gtagtgataa tcatagcatc ttcggtgctg ggacccgact caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000036             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:13996:5331
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000036
VERSION     KCVO01000036.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13996:5331"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72065.1"
                     /translation="DYYCSSDTSSSTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           83 a          153 c          126 g          113 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtggtt ttgagcgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc ttgatttatg aggtcagtta tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctgccaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tattgcagct cagacacaag tagtagtact tgggtattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000037             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:17837:8654
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000037
VERSION     KCVO01000037.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17837:8654"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72066.1"
                     /translation="DYYCFSSDSSSDHWVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>449
                     /gene="IGLC"
BASE COUNT           88 a          138 c          120 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctgt gaggacagga
      241 aacggtcctc tgggatccct gagagattct ctggctccag ctcagggaca atggccacct
      301 tgactatcag tggggcccag gtggaggatg aaggtgacta ctactgtttc tcatcagata
      361 gcagttctga tcattgggtg ttcggcggag ggacccggct gaccgtccca ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000038             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:5758:8680
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000038
VERSION     KCVO01000038.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5758:8680"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72067.1"
                     /translation="DYYCSSYASSSTWIF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           88 a          156 c          123 g          106 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat aatttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacgcaagca gtagcacttg gatattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000039             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:17840:7498
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000039
VERSION     KCVO01000039.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17840:7498"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72068.1"
                     /translation="DYYCQVWDNCNDHIFF"
     J_segment       399..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          146 c          136 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaga taaatatatt cactggtacc agcagaaacc agcgcaggcc cctgtgctgg
      241 tcatctacta tgatagtgac cggccctcat ggatccctga gcgattctct gggtccaagt
      301 cagggagcac cgccaccctg accatcagcg gggccggggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacaat tgtaatgatc atatcttttt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000040             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:17880:13790
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000040
VERSION     KCVO01000040.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17880:13790"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..444
                     /note="immunoglobulin light chain variable region"
     V_region        111..444
     V_segment       111..404
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72069.1"
                     /translation="DYYCSLWDSRLSSRVF"
     J_segment       409..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          154 c          127 g          109 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctct ccttctcact ctgctggttc actgcacagg gtcctgggcc cagtctgtgc
      121 tgacgcagcc gccctcagca tctggggccc ccgggcagag ggtcaccatc tcctgcactg
      181 ggaccagctc caacatcggg gcgaattatt atgtttcctg gtaccagcag tttccaggaa
      241 cagcccccaa actcctcatc tatgaaaata ataagcgacc ctcaggggtt tctgaccgat
      301 tctctggctc caagtctggt acctcagcct ccctgaccat ctctggactc caatctgagg
      361 atgaggctga ttattactgc tcactatggg atagcaggct gagtagtcgg gtattcggcg
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000041             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:8518:17966
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000041
VERSION     KCVO01000041.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:8518:17966"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72070.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       404..438
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           83 a          157 c          122 g          114 t
ORIGIN      
        1 acatgggggg ctggggtctc agacggcagc gctctcggga catctccacc atggcctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccctga
      121 ctcagcctcg ctcagtgtct gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga catcggtact tataactatg tctcctggta ccaacagcat ccaggcacag
      241 cccccaaact catgattttt gaggtcagtg agcggccctc aggggtctct gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag gctgaggacg
      361 aggctgatta ttactgttgc tcatatgcag acacctacac ttttgtgttt ggaggtggca
      421 ccagattgac cgtcctcggt cagcccaagg cttccccctt ggtcactctg ttcccg
//
LOCUS       KCVO01000042             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:8634:10262
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000042
VERSION     KCVO01000042.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8634:10262"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..406
                     /note="immunoglobulin light chain variable region"
     V_region        87..406
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72071.1"
                     /translation="DYYCYSTDTSAYHVF"
     J_segment       375..406
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>446
                     /gene="IGLC"
BASE COUNT           89 a          138 c          116 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgaggtgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacacta
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggtcacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttat tcaacagata
      361 ctagtgctta tcatgtattc ggcggaggga cccggctgac cgtcctgggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000043             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:21757:17473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000043
VERSION     KCVO01000043.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:21757:17473"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72072.1"
                     /translation="DYYCYSIDINGNQSIF"
     J_segment       394..424
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           94 a          141 c          121 g          106 t
ORIGIN      
        1 acatggggtg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactccccc tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacaacca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agatgcattg
      181 ccaaaaaaat ttgcttattg gttccagcag aagccaggcc agtccccttt actggtcatc
      241 tatgaggaca gtgagcggcc ctcggggatc cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cagtggggcc caggtggagg atgaagctga ctactactgt
      361 tactcaatag atatcaatgg taatcagagc attttcggtg ctgggacccg gctcaccgtc
      421 ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01000044             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:22596:4520
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000044
VERSION     KCVO01000044.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22596:4520"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..382
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72073.1"
                     /translation="DFYCQSTDSSGYIF"
     J_segment       383..419
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT          101 a          134 c          118 g          104 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgtggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 gacaaaaaat tatgctcagt ggttccagca gaagccaggc caggcccctg tgctgctgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagtt ccagttcagg
      301 gacaacagtt accttgacca tcagtcgggc ccaggtagaa gatgaggctg acttttattg
      361 tcaatcaaca gacagcagtg gttacatctt cggtgctggg acccggctca ccgtcctagg
      421 tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01000045             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:10216:6078
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000045
VERSION     KCVO01000045.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:10216:6078"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72074.1"
                     /translation="DYYCYSSDTSADYWVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           91 a          142 c          126 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggtt ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcatca gataccagtg ctgattattg ggtgttcggc ggagggaccc ggctgaccgt
      421 cccaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000046             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:24278:8865
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000046
VERSION     KCVO01000046.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:24278:8865"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..442
                     /note="immunoglobulin light chain variable region"
     V_region        113..442
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72075.1"
                     /translation="DYFCAVWDDSLSGVLF"
     J_segment       407..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>481
                     /gene="IGLC"
BASE COUNT           90 a          154 c          127 g          110 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcctcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggatg agtgtcacca tctcctgttc
      181 tggaagcacc tccaacatcg gaagtaacag tgtgtcctgg tacctgcagc tcccggaaac
      241 ggctcccaaa ctcctcatct attataatga tcggcgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggcc cgtcagcctc cctggccatc agtgggctcg agaccgaaga
      361 tgaggctgat tatttctgcg cagtatggga tgatagcctg agcggtgtgt tattcggagg
      421 agggacccga ctgaccgtcc taagtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01000047             395 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:22808:17800
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000047
VERSION     KCVO01000047.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 395)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:22808:17800"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    27..357
                     /note="immunoglobulin light chain variable region"
     V_region        27..357
     V_segment       27..321
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <285..>329
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72076.1"
                     /translation="DYYCSSYASSSTWIF"
     J_segment       327..357
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        358..>395
                     /gene="IGLC"
BASE COUNT           74 a          123 c          104 g           94 t
ORIGIN      
        1 acatgggggg cacaggatcc tgggctcagg ctgccctgac tcagtctccc tctgtgtctg
       61 ggtctcctgg acagtcggtc accatttcct gcactggaac cagcagtgac attggtggtt
      121 ataaccgtgt ctcctggtac caacagcacc caggcaaagc ccccaaactc atgatttatg
      181 aggtcagtaa tcggccctca ggggtctctg atcgcttctc tggctccaag tctggcaaca
      241 cggcctccct gatcatctct gggttccagt ctgaggacga ggctgattat tattgcagct
      301 catacgcaag cagtagcact tggattttcg gcggagggac ccggctgacc gtcctaggtc
      361 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000048             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:21622:20038
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000048
VERSION     KCVO01000048.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:21622:20038"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..414
                     /note="immunoglobulin light chain variable region"
     V_region        93..414
     V_segment       93..374
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <342..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72077.1"
                     /translation="DYYCQVWDSSSDVFF"
     J_segment       377..414
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           86 a          135 c          134 g           97 t
ORIGIN      
        1 acatgggggg aagcagcctt ggcggtgcct cagccatggc cgggaccctt ctcctcctcg
       61 gcctccttgc tcactgcaca gactctgtgg tctcctatga attgactcag ccacgctcag
      121 tgtccgtgtc cccaggacag acggccagga tcacctgtgg gggagacttc attggaagta
      181 gaagtgtgca gtggtaccaa cagaagccac cgcaggccct tgtactggtc atctatggtg
      241 atagcgaacg gccctcaggg atccctgagc gattctctgg ctccaattta gggaataccg
      301 ccaccctgac catcaacggc gtcgaggccg gggatgaggc tgactattac tgtcaggtgt
      361 gggacagtag tagtgatgtg ttcttcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000049             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:20818:15755
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000049
VERSION     KCVO01000049.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:20818:15755"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72078.1"
                     /translation="DYYCYSTRSSGYHGLF"
     J_segment       375..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           90 a          139 c          116 g          104 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatctct gagagattct ctggttccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtgcaggatg aagctgacta ctactgttac tcaactcgta
      361 gcagtggtta tcatggctta ttcggaggag ggacctggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000050             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:10429:13446
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000050
VERSION     KCVO01000050.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10429:13446"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72079.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          161 c          120 g          106 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc acttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000051             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:28765:11510
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000051
VERSION     KCVO01000051.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:28765:11510"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72080.1"
                     /translation="DYYCSSYASSSTWIF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          156 c          121 g          106 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcaggacac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcata atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcag tagcacttgg atattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000052             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:20241:18030
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000052
VERSION     KCVO01000052.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:20241:18030"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72081.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          142 c          139 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gctgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gtgggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga acgattctct ggctccaaat
      301 cagggagcgc cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000053             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:15357:18628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000053
VERSION     KCVO01000053.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15357:18628"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..430
                     /note="immunoglobulin light chain variable region"
     V_region        104..430
     V_segment       104..399
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72082.1"
                     /translation="DYFCSSYTGSITLF"
     J_segment       400..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>469
                     /gene="IGLC"
BASE COUNT           87 a          157 c          117 g          108 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcaggacgtc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctct gtgtctggat ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggtaccaa cggcacccag gcaaagcccc
      241 caaactcatg atttatgatg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaaatct ggcaacacgg cctccctgac catctctggg ctccagtctg aggatgaggc
      361 tgattatttc tgcagctcat atacaggcag catcacttta ttcggaggag ggacccggct
      421 gaccgtccta cgtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000054             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:14030:5162
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000054
VERSION     KCVO01000054.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14030:5162"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..431
                     /note="immunoglobulin light chain variable region"
     V_region        104..431
     V_segment       104..400
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72083.1"
                     /translation="DYYCSSYAVGNTFF"
     J_segment       401..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           88 a          155 c          118 g          108 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcaggacgtc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaatcag
      181 caatgacatc ggtacttata actatgtctc ctggtaccag caacacccag gcaaagcccc
      241 caaattcatg atttatgatg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 gtccaaatct ggcaacacgg cctccctgac catctctggc ctccaggctg aggatgaggc
      361 tgattattac tgcagctcat atgcagtagg caacactttc ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000055             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:13696:18636
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000055
VERSION     KCVO01000055.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13696:18636"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..418
                     /note="immunoglobulin light chain variable region"
     V_region        99..418
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72084.1"
                     /translation="DYYCHSLDTSGNDVF"
     J_segment       390..418
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>458
                     /gene="IGLC"
BASE COUNT           90 a          143 c          125 g          100 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcactgc
      181 caaaaaaatt tgcttactgg ttccagcaga agccaggcca gtcccctgtg gcgatcatct
      241 atgaggacag caaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc agtggggccc aggtggagga tgaagctgac tactactgtc
      361 attcattaga taccagtggt aatgatgttt tcggcggagg gacccggctg accgtcctgg
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000056             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:20640:14423
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000056
VERSION     KCVO01000056.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20640:14423"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72085.1"
                     /translation="DYYCYSRDGSENQSVF"
     J_segment       393..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           98 a          137 c          124 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgtatatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac aacaaacggc cctctgggat tcctgagaga ttctccggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaaggtg actattactg
      361 ttattcaaga gatggtagtg aaaatcaaag cgtcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000057             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:16748:11331
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000057
VERSION     KCVO01000057.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16748:11331"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..309
                     /note="immunoglobulin light chain variable region"
     V_region        87..309
     V_segment       87..269
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>281
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72086.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       273..309
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        310..>347
                     /gene="IGLC"
BASE COUNT           69 a          105 c           97 g           76 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagc agaaggcagg ccagtcccct gtgctgatca
      121 tctatgagga cagcaaacgg ccctctggga tccctgagag attctctggc tccagttcag
      181 ggacaatggc caccttgact atcagtgggg cccaggtgga ggatgaaggt gactactact
      241 gttactcaac agataacagt gatactcata ggggcttctt cggaggaggg acccggctga
      301 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000058             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:20846:8510
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000058
VERSION     KCVO01000058.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20846:8510"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..407
                     /note="immunoglobulin light chain variable region"
     V_region        86..407
     V_segment       86..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <335..>379
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72087.1"
                     /translation="DYYCSSTDNSGNYVF"
     J_segment       374..407
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>445
                     /gene="IGLC"
BASE COUNT           91 a          140 c          116 g           98 t
ORIGIN      
        1 acatggggag agctctgggt gtctcaccat ggcctggatt cctctcctac tccccctcct
       61 cactttctgc acaggctctg cagcctccta tgagctgaca cagccaccct cggtgtcagt
      121 gtccccagga cagacggcca ggatcacctg ctctggagat gcattgccag aaaaatatgc
      181 ttattggttc cagcagaagc caggccagtc ccctgtgctg atcatcaatg aggacagcaa
      241 acggccctct gggatccctg agagattctc tggctccagc tcagggacag tggccacctt
      301 gactctcagt ggggcccagg tggaggatga agctgactac tactgttcct caacagataa
      361 cagtggtaat tatgtattcg gcggagggac ccggctgacc gtcctaggtc agcccaaggc
      421 tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000059             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:27075:9297
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000059
VERSION     KCVO01000059.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:27075:9297"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72088.1"
                     /translation="DYYCGSCTSGITYIF"
     J_segment       402..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           80 a          158 c          127 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcgggac gtctccacca tggcttgggc
       61 tctggtcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggagc
      181 cagcggtgac attggtggtt ataacggtgt ctcctggtac cagcagcact caggcacagc
      241 ccccagactc ctgatttatg aggtcactaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgcggct catgtacgag tggaatcact tacatcttcg gtgctgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCVO01000060             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:20169:10321
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000060
VERSION     KCVO01000060.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20169:10321"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..306
                     /note="immunoglobulin light chain variable region"
     V_region        87..306
     V_segment       87..266
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <228..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72089.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       270..306
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           68 a          105 c           95 g           76 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacaga aggcaggcca gtcccctgtg ctgatcatct
      121 atgaggacag caaacggccc tctgggatcc ctgagagatt ctctggctcc agttcaggga
      181 caatggccac cttgactatc agtggggccc aggtggagga tgaagctgac tactactgtt
      241 actcaacaga taacagtgat actcataggg gcttcttcgg aggagggacc cggctgaccg
      301 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000061             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:19090:13490
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000061
VERSION     KCVO01000061.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:19090:13490"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..426
                     /note="immunoglobulin light chain variable region"
     V_region        97..426
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72090.1"
                     /translation="DYYCAAWDNILSGPLF"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>465
                     /gene="IGLC"
BASE COUNT           93 a          154 c          117 g          101 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcctc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaac
      181 atcggaagta atagtgtatc ctggtaccag cagctcccag aaacggctcc caaactcctc
      241 atctattata atgatcggcg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggataacat cctgagcggt cccttattcg gaggagggac ccggctgacc
      421 gtcctaagtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000062             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:16167:13033
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000062
VERSION     KCVO01000062.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16167:13033"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..423
                     /note="immunoglobulin light chain variable region"
     V_region        101..423
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72091.1"
                     /translation="DYYCQVWDITTDHDVF"
     J_segment       389..423
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>463
                     /gene="IGLC"
BASE COUNT           97 a          139 c          125 g          102 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatgacct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ttctgcggcc tcctatgagc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacct
      181 tggaagtaaa aatatacact ggtaccagca aaagccaccg caggcccctg tactggtcat
      241 ctattatgat gtcgaacggc cctcagggat ccctgagcga ttctctggcg ccaaatcagg
      301 aaacaccgcc accctcatca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattacta ctgatcatga tgtattcgga agtggcacca agttgaccgt
      421 ccttggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01000063             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:16953:5924
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000063
VERSION     KCVO01000063.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:16953:5924"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72092.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           84 a          156 c          119 g          113 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtacttata actatgtctc ctggtaccaa caacatccag gcacagcccc
      241 caaactcatg atttttgagg tcagtgagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgttgctcat atgcagacac ctacactttt gtgtttggag gtggcaccag
      421 attgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01000064             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:15320:14318
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000064
VERSION     KCVO01000064.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15320:14318"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..427
                     /note="immunoglobulin light chain variable region"
     V_region        105..427
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72093.1"
                     /translation="DYYCQVWDSSSDHWVF"
     J_segment       392..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>467
                     /gene="IGLC"
BASE COUNT           85 a          147 c          142 g           93 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca caggctctgc ggtctcctat gaactgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggcccg gatcacctgt gggggagaca
      181 acattggaag taaaagtgtg cagtggttcc agcagaaggc accgcaggcc cctgtcctgg
      241 tcatttatgg tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cgggaatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgggtatt cggcggaggg acccggctga
      421 ccgtcctcgg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000065             328 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:25371:18265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000065
VERSION     KCVO01000065.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 328)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 328)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:25371:18265"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..290
                     /note="immunoglobulin light chain variable region"
     V_region        8..290
     V_segment       8..252
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <215..>262
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72094.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       256..290
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        291..>328
                     /gene="IGLC"
BASE COUNT           71 a           94 c           93 g           70 t
ORIGIN      
        1 acatggggga cagacggcca ggatcacctg ctctggagat gcattgccaa aaaagtatgc
       61 ttattggttc cagcagaagc caggccagtc ccctgtgctg atcatctatg aggacagcag
      121 acggccctct gggatccctg agagattctc tgcctccagc tcagggacag tggccacctt
      181 gactatcagt ggggcccagg gggaggatga agctgactac tactgttatt caatggatag
      241 cagtggtact cagagcatct tcggtgctgg gacccggctc accgtcctag gtcagcccaa
      301 ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCVO01000066             382 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:25064:6653
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000066
VERSION     KCVO01000066.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 382)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:25064:6653"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..344
                     /note="immunoglobulin light chain variable region"
     V_region        20..344
     V_segment       20..307
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <269..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72095.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       311..344
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>382
                     /gene="IGLC"
BASE COUNT           78 a          110 c          115 g           79 t
ORIGIN      
        1 acatgggggc tctgcggtct cctatgacct gactcagcca ccctcggtgt cagtgtcccc
       61 aggacagacg gccaggatca cctgtgtggg agacaatgtt ggaagtgaat atgtgcactg
      121 gtaccaacag aagccaccgc aggcccctgt ggtggtcatc cattataata gtgaccggcc
      181 ctcagggatc cctgaacgat tctctggctc caaatcaggg agcgccgcca ccctgaccat
      241 cagcggggtc gaggccgggg atgaggctga ctattactgt caggtgtggg acagtagtag
      301 tgatcatagt ttattgggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc
      361 cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000067             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:3621:11049
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000067
VERSION     KCVO01000067.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:3621:11049"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..437
                     /note="immunoglobulin light chain variable region"
     V_region        92..437
     V_segment       92..398
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72096.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          160 c          121 g          106 t
ORIGIN      
        1 acatggggtg gcctcagagg tagccgtgtc caccatggcc ctgactcctc tcctcctcct
       61 gctcctctct cactgcacag gttccctctc ccagcctgtg ctgactcagc caccctccct
      121 gtctgcatcc ccgggagcat cggccagact cccctgcacc ctgagcagtg acctcagtgt
      181 tggtagtaaa aacatgtact ggtaccagca gaagccaggg agcgctccca ggttattcct
      241 gtactactac tccgactcag acaagcagct gggacctggg gtccccaatc gagtctctgg
      301 ctccaaggag acctcaagta acacagcgtt tttgctcatc tctgggctcc agcctgagga
      361 cgaggccgat tattactgtc aggtgtatga cagtactgga gtgttgttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000068             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:23754:19491
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000068
VERSION     KCVO01000068.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:23754:19491"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72097.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           84 a          152 c          124 g          112 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttttg agcgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcttg atttatgagg tcagttatcg gccctcaggg gactctgatc gcttctctgg
      301 ttccaagtct gccaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattat tgcagctcat acacaagtag tagtacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000069             341 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:26542:20356
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000069
VERSION     KCVO01000069.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 341)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:26542:20356"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..303
                     /note="immunoglobulin light chain variable region"
     V_region        87..303
     V_segment       87..266
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <228..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72098.1"
                     /translation="DYYCYSTDSSDNHSIF"
     J_segment       269..303
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>341
                     /gene="IGLC"
BASE COUNT           69 a          104 c           90 g           78 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacaga agccaggcca gtcccctgtg atgatcatct
      121 atgaggacag caaacggccc tctgggatcc ctgagagatt ctctggctcc agttcaggga
      181 cagtggccac cttgactatc agtggggccc aggtggagga tgaagctgac tactactgtt
      241 actcaacaga tagtagtgat aatcatagca tcttcggtgc tgggacccga ctcaccgtcc
      301 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCVO01000070             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:22070:17311
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000070
VERSION     KCVO01000070.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22070:17311"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72099.1"
                     /translation="DYYCQVWDSTNDHILF"
     J_segment       395..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          147 c          136 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gaactgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaga taaatatgta cactggtacc agcagaagcc agcgcgggcc cctgtgctgg
      241 tcgtctacta tgatactgac cggccctcat ggatccctga gcgattctct gggtccaaat
      301 cggggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt actaatgatc atatcttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000071             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:7870:10070
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000071
VERSION     KCVO01000071.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:7870:10070"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72100.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           84 a          162 c          118 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc ctttcctaca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa caccacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac ttccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000072             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:17693:4662
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000072
VERSION     KCVO01000072.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:17693:4662"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72101.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          142 c          124 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tactgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgggaga ttctctggat ccacctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagtagtg gtaattatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000073             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:14540:19908
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000073
VERSION     KCVO01000073.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14540:19908"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..445
                     /note="immunoglobulin light chain variable region"
     V_region        117..445
     V_segment       117..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72102.1"
                     /translation="DYYCQSYDSSLRAVLF"
     J_segment       411..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>485
                     /gene="IGLC"
BASE COUNT           88 a          158 c          131 g          108 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcagtgggag tacctccaac attgggggtt attatgtgca gtggtaccag cagcttccaa
      241 gaacggcccc caaactcctc atctatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggtgcctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgactattac tgccagtcct atgacagcag cctgagagcc gtgttattcg
      421 gaggagggac ccggctgacc gtcctgggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01000074             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:16000:10954
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000074
VERSION     KCVO01000074.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16000:10954"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72103.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       393..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          143 c          123 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc tccatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac atcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaata gatagcagtg gtagtcatag cgtcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000075             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:17722:16017
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000075
VERSION     KCVO01000075.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:17722:16017"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72104.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          161 c          123 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac cattgccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000076             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:20654:5993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000076
VERSION     KCVO01000076.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20654:5993"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72105.1"
                     /translation="DYYCQVWDITTDHDVF"
     J_segment       389..425
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          139 c          130 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatgacct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ttctgcggcc tcctatgaac tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccagggtc acctgtgggg gagacaacat
      181 tggaagtaaa aatgtgcact ggtaccagca gaagccaccg caggcccctg ttctggtcat
      241 ctattatgat accgaacggc cctcagggat ccctgagcga ttctctggcg ccaaatcagg
      301 gaacaccgcc accctgatca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattacta ctgatcatga tgtgttcgga agtggcacca agttgaccgt
      421 cctcggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01000077             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:13206:21340
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000077
VERSION     KCVO01000077.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13206:21340"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..445
                     /note="immunoglobulin light chain variable region"
     V_region        114..445
     V_segment       114..405
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <369..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72106.1"
                     /translation="DYYCQSSDTSLNDHVLF"
     J_segment       410..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>485
                     /gene="IGLC"
BASE COUNT           96 a          159 c          119 g          111 t
ORIGIN      
        1 acatggggct gcttcatctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctcgtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacaca gccgccctca gtgtctgggg ccccagggca gaggatcacc atctcctgca
      181 ctgggagcag ctccaacatt ggaggttatt atgtatactg gtaccagcaa ctcccaggaa
      241 tggcccccaa actcctcatc tatgacaata ataagcgacc ctcaggggtt tctgaccgat
      301 tctctggctc caagtctggt acctcagcct ccctgaccat cgctgggctc cagactgagg
      361 atgaggctga ttattactgc caatcctctg acaccagtct aaatgatcat gtgttattcg
      421 gaggagggac ccggctgagc gtcctcggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01000078             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:20338:11819
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000078
VERSION     KCVO01000078.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20338:11819"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72107.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          125 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg cccgactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000079             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:16441:12758
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000079
VERSION     KCVO01000079.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:16441:12758"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72108.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       393..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          142 c          125 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaagac gacaaacggc cctctgggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaata gatagtagtg gtagtcatag cgtcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000080             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:8982:3912
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000080
VERSION     KCVO01000080.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8982:3912"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    77..398
                     /note="immunoglobulin light chain variable region"
     V_region        77..398
     V_segment       77..358
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <326..>370
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72109.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       362..398
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        399..>436
                     /gene="IGLC"
BASE COUNT           94 a          139 c          110 g           93 t
ORIGIN      
        1 acatgggggg tgtctcacca tggcctggat tcctctccta ctccccatcc tcactttctg
       61 cacaggctct gcagcctcct atgagctgac acagccaccc tcgttgtcag tgtccccagg
      121 acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg cttattggta
      181 ccagcagaaa ccaggccagt cccctatgct gatcatctat gaggacaaca aacggccctc
      241 tgggatccct gaaagattct ctggctccag ctcagggaca gtggccacct tgactatcac
      301 tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca acagtggtca
      361 gggctcattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc
      421 ggtcactctc ttcccg
//
LOCUS       KCVO01000081             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:22966:6122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000081
VERSION     KCVO01000081.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:22966:6122"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72110.1"
                     /translation="DYYCSSYASSSTWIF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          156 c          122 g          105 t
ORIGIN      
        1 acaggggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcata atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcag tagcacttgg atattcgacg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000082             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:16344:7780
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000082
VERSION     KCVO01000082.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16344:7780"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72111.1"
                     /translation="DYYCQVWDSITDHSIF"
     J_segment       390..424
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           86 a          147 c          132 g           97 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctta ctgcacagtc tctgcggtct cctatgagct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg ggacaacatt
      181 ggaactgaat atgtgcactg gtaccagcag aagccaccgc aggcccctgt ggtggtcatc
      241 tattataata ctgaccggcc ctcagggatc cctgagcgat tctcaggctc caaatcaggg
      301 aacaccggca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtattac tgatcattcc atcttcggtg ctgggacccg gctcaccgtc
      421 ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01000083             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:9154:14493
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000083
VERSION     KCVO01000083.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:9154:14493"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72112.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          157 c          128 g          109 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcac catctcctgc
      181 actgggagca gctccaacat tggaggttat tatgtgcagt ggtaccagca gcttccagga
      241 acggccccca aactcctcat gtatgaaaat aataagcgac cctcaggggt ttctgatcga
      301 ttctctggct cccagtctgg tacctcagcc tccctgacca tcactggact ccagtctgag
      361 gatgaggctg attattactg ccagtcctat gacagcagcc tgagtgccgt gttattcgga
      421 gcagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01000084             400 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:12829:12787
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000084
VERSION     KCVO01000084.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 400)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 400)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12829:12787"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    32..362
                     /note="immunoglobulin light chain variable region"
     V_region        32..362
     V_segment       32..326
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <290..>334
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72113.1"
                     /translation="DYYCSSYASSSTWIF"
     J_segment       327..362
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        363..>400
                     /gene="IGLC"
BASE COUNT           78 a          127 c          104 g           91 t
ORIGIN      
        1 acatgggact cagggcacag gatcctgggc tcaggctgcc ctgactcagt ctccctctgt
       61 gtctgggtct cctggacagt cggtcaccat ttcctgcact ggaaccagca gtgacattgg
      121 tgattataac cgtgtctcct ggtaccaaca gcacccaggc aaagccccca aactcataat
      181 ttatgaggtc agtgatcggc cctcaggggt ctctgatcgc ttctctggct ccaagtctgg
      241 caacacggcc tccctgatca tctctgggct ccaggctgag gacgaggctg attattactg
      301 cagctcatac gcaagcagta gcacttggat attcggcgga gggacccggc tgaccgtcct
      361 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000085             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:11619:10601
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000085
VERSION     KCVO01000085.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11619:10601"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72114.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           89 a          142 c          117 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatttg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gcagtggtaa tcatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000086             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:16848:15831
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000086
VERSION     KCVO01000086.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16848:15831"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72115.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           91 a          141 c          116 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gcagtggtaa ttatgtattc ggcggaggga cccgactgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000087             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:10867:6541
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000087
VERSION     KCVO01000087.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10867:6541"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..438
                     /note="immunoglobulin light chain variable region"
     V_region        90..438
     V_segment       90..398
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72116.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       401..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          155 c          119 g          108 t
ORIGIN      
        1 acatgggggt ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcca agcctatgct gactcagccg gcctccctct
      121 cagcatctcc tggagcatca gccagtctca catgcacctt cagcggtggc atcaatgttg
      181 ctggctacca catacactgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 gatacaaatc agactcagat aagggccagg gctctggagt ccccagccgc ttctctggat
      301 ccaaagatgg ttcagcgaac acagggattt tacgcatctc tgggctccag tctgaggatg
      361 aggctgacta ttactgtgcc attggacaca gcagcggtga ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCVO01000088             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:19569:16926
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000088
VERSION     KCVO01000088.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19569:16926"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72117.1"
                     /translation="DYYCYSSDSNADYWVF"
     J_segment       389..419
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>463
                     /gene="IGLC"
BASE COUNT           92 a          141 c          127 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggtt ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcatca gatagcaatg ctgattattg ggtgttcggc ggagggaccc ggctgaccgg
      421 cccaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000089             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:6852:18779
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000089
VERSION     KCVO01000089.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6852:18779"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..423
                     /note="immunoglobulin light chain variable region"
     V_region        93..423
     V_segment       93..385
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72118.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       387..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           86 a          151 c          121 g          103 t
ORIGIN      
        1 acatggggga ggcagcactc aggacagtct ccagcatggc ctggtctcct ctcctcctca
       61 cccttctcat tcactgcaca gggtcctggg cccagtctgt gctgacgcag ccgccctcag
      121 tgtctggggc gcccgggcag agggtcacca tctcctgcac tgggagcagc tccaacattg
      181 gaggttatta tgtgcagtgg taccagcagc ttccaggaac ggcccccaaa ctcctcatgt
      241 atgaaaataa taagcgaccc tcaggggttt ctgatcgatt ctctggctcc cagtctggta
      301 cctcagcctc cctgaccatc actggactcc agtctgagga tgaggctgat tattactgcc
      361 agtcctatga cagcagcctg agtgccgtgt tattcggagc agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000090             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:25394:16060
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000090
VERSION     KCVO01000090.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:25394:16060"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72119.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           92 a          143 c          116 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag ccaggccagt cccctgtgct aatcatctat gacgacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcat tggggcccag gtggaggatg aagctgacta ccactgtttc tcaacagata
      361 gcagtggtaa tcataggggc ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000091             320 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:8784:20697
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000091
VERSION     KCVO01000091.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 320)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8784:20697"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..282
                     /note="immunoglobulin light chain variable region"
     V_region        5..282
     V_segment       5..242
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <204..>254
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72120.1"
                     /translation="DYYCYSTDNYNYHRVFF"
     J_segment       252..282
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        283..>320
                     /gene="IGLC"
BASE COUNT           71 a           91 c           84 g           74 t
ORIGIN      
        1 acatgggcag gatcacctgc tctggagatg ctttgccaga aaaatttgct tattggttcc
       61 agcagaagcc aggccagtcc cctgtactga tcatctatga ggacagcaaa cggccctctg
      121 ggatccctga gagattctct ggctccagct cagggacagt ggccaccttg actatcagtg
      181 gggcccaggt ggcggatgaa gctgactact actgttactc aacagataac tataattatc
      241 atagggtctt cttcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc
      301 cctcggtcac tctcttcccg
//
LOCUS       KCVO01000092             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:21522:14776
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000092
VERSION     KCVO01000092.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21522:14776"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..381
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72121.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       385..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           98 a          144 c          121 g           96 t
ORIGIN      
        1 acatgggggg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactcccca tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcgttgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agatgcattg
      181 ccagaaaaat atgcttattg gtaccagcag aaaccaggcc agtcccctat gctgatcatc
      241 tatgaggaca acaaacggcc ctctgggatc cctgaaagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cactggggcc caggtggagg atgaagctga ctactactgt
      361 tactcagcag acaacagtgg tcagggctca ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000093             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:8155:10074
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000093
VERSION     KCVO01000093.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:8155:10074"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72122.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          157 c          120 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggttccaa cagcacccag gcaaagcccc
      241 caaactcatg atttgtgacg tcagtaatcg gccctcaggg gtctctactc acttctctgg
      301 ttccaagtct ggcaatacgg cctccctgat catctctgga ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcag tagcacttgg gttttcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000094             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:22936:7807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000094
VERSION     KCVO01000094.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:22936:7807"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72123.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           88 a          158 c          128 g          109 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc actgtctggg gcgcccgggc agagggtcac catctcctgc
      181 actgggagca gctccaacat tggaggttat tatgtgcagt ggtaccagca gcttccagga
      241 acggccccca aagtcctcat ctatgaaaat aataagcgac cctcaggggt ttctgatcgc
      301 ttctctggct cccagtctgg tacctcagcc tccctgacca tcactggact ccagtctgag
      361 gatgaggctg attattactg ccagtcctat gacagcagcc tgagtgccgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01000095             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:21809:6975
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000095
VERSION     KCVO01000095.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21809:6975"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72124.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          161 c          126 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcggccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000096             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:15750:16116
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000096
VERSION     KCVO01000096.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15750:16116"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72125.1"
                     /translation="DYYCTSYASTTTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           84 a          162 c          120 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtggtt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttttg acgtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcacct catacgcaag cactaccact tggctattcg gcggagggac
      421 ccgcctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000097             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:15027:6355
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000097
VERSION     KCVO01000097.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15027:6355"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72126.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       393..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           94 a          142 c          123 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccaaca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaagac gacaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaata gatagtagtg gtagtcatag cgtcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000098             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:13907:14501
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000098
VERSION     KCVO01000098.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13907:14501"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72127.1"
                     /translation="DYYCSSYASSSSWKF"
     J_segment       403..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          154 c          126 g          106 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctgggaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatc atttatgagg tcagtgatcg ggcctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcag tagcagttgg aaattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000099             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:15226:4187
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000099
VERSION     KCVO01000099.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15226:4187"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72128.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          161 c          121 g          108 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtggtt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg acgtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacgcaag cactaccact tggctattcg gcggagggac
      421 ccgcctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000100             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:10509:19642
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000100
VERSION     KCVO01000100.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10509:19642"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72129.1"
                     /translation="DYYCSSYTNYSTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          155 c          122 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacacaaa ttatagcact tgggtattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000101             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:22682:13803
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000101
VERSION     KCVO01000101.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22682:13803"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72130.1"
                     /translation="DYYCQVWDSSSDHWVF"
     J_segment       393..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          143 c          135 g           99 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagcctctgt ggtctcctat gagctgactc
      121 agtccccctc ggtgtcagtg tccccagggc agacggccag gatcgcctgt gggggagaca
      181 accttataaa tgaatatgtg cactggtacc aacagaaacc agcgcaggtc cctatactgg
      241 tcatctatta tgatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaaaac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt atgggacagt agtagtgatc attgggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000102             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:11133:17430
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000102
VERSION     KCVO01000102.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:11133:17430"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72131.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           95 a          144 c          122 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagacaaa tatgcttatt ggtaccggca gaaaccaggc cagtccccta tactgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgaaaga ttctctggct ccagttcagg
      301 gacagtggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 ttactctgca gacaacagtg gtcagggctc attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000103             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:13949:16664
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000103
VERSION     KCVO01000103.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13949:16664"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72132.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       400..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          148 c          135 g           97 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acaggctctg cggtctccta tgagctgact
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 aaccttggag ataagtatct acactggtac caccagaagc cagcgcaggc ccctgtcctg
      241 gtcatctact atgatagtga ccggccctca tggatccctg agcgattctc tgggtccaag
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag taataatgat catatctttt tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000104             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:8934:10984
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000104
VERSION     KCVO01000104.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:8934:10984"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..427
                     /note="immunoglobulin light chain variable region"
     V_region        104..427
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72133.1"
                     /translation="DYFCCSYADTYTFVF"
     J_segment       404..427
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>472
                     /gene="IGLC"
BASE COUNT           83 a          156 c          122 g          111 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actttgtctc ctggtaccaa caacatccag gcacagcccc
      241 caaactcatg atttatgagg tcaatcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctcaaagtct ggcaacacgg cctccctgac cgtcgccggg gtccaggctg aggacgaggc
      361 tgattatttc tgctgctcat atgcagacac ctacactttt gttttcggaa gtggcaccag
      421 gttgaccgtc gtcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01000105             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:16909:3404
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000105
VERSION     KCVO01000105.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16909:3404"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72134.1"
                     /translation="DYYCGSYRRGTTWIF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           82 a          157 c          127 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcgggac gtctccacca tggcttgggc
       61 tctggtcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtccgtc accatctcct gcactggaac
      181 cagcagtgac attggtgatt ataacgctgt ctcctggtac cagcagtact caggcacagc
      241 ccccagactc ctgatttatg aggtcactca gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggctaca cggcctccct gaccatttct gggctccagg ctgaggatga
      361 ggctgattat tactgcggct catataggag gggaaccact tggatattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000106             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:24086:4594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000106
VERSION     KCVO01000106.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:24086:4594"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    129..450
                     /note="immunoglobulin light chain variable region"
     V_region        129..450
     V_segment       129..416
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72135.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       417..450
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT          100 a          149 c          135 g          104 t
ORIGIN      
        1 acatggggag agaagcctag ggagcccagc tgtgctgtgg gctcaggagg cagagctctg
       61 ggtgtctcac catggcctgg attcctctcc tactccccct cctcactttc tgcacaggct
      121 ctgcagcctc ctatgagctg acacagccac cctcggtgtc agtgtcccca ggacagacgg
      181 ccaggatcac ctgctctgga gatgcattgc cagaaaaata tgcttattgg ttccagcaga
      241 agccaggcca gtcccctgtg ttgatcatca atgaggacag caaacggccc tctgggatcc
      301 ctgagagaat ctctggctcc agctcaggga cagtggccac cttgactctc agtggggccc
      361 aggtggagga tgaagctgac tactactgtt cctcaacaga tagtagtggt aatcatgtat
      421 tcggcggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCVO01000107             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:3250:10154
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000107
VERSION     KCVO01000107.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:3250:10154"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..395
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72136.1"
                     /translation="DYYCLLYSSGVHLF"
     J_segment       397..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           96 a          154 c          114 g          104 t
ORIGIN      
        1 acatggggtc tggagccaga gatcccttcc aataccagca ccatggcctg gactctgctc
       61 ctcctccagt tcctcctcac ttgctgccca gggtccaatt ctcaggctgt agtgactcag
      121 gagccctcaa tgactgtgtc cccaggaggg acagtcactc tcacctgtgg ctccagcact
      181 ggagcagtca ccagtagtaa ttttccaaac tggttccagc agaaacctgg acaagtcccc
      241 aggggactga tttacaatac acacaacaaa cactcctgga cccctgcccg gttctcaggc
      301 tccctcgctg gggccaaagc tgccctgaca ctgtcaggtg cacagcccga ggacgaggct
      361 gactattact gcttgctgta ttctagtggt gttcatttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000108             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:20382:15748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000108
VERSION     KCVO01000108.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20382:15748"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..254
                     /note="immunoglobulin light chain variable region"
     V_region        8..254
     V_segment       8..213
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72137.1"
                     /translation="DYYCQVWDSSSKCVLF"
     J_segment       221..254
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>292
                     /gene="IGLC"
BASE COUNT           64 a           81 c           87 g           60 t
ORIGIN      
        1 acatgggatt ggaagtaaaa atgtgcactg gtaccagcag aagccagcgc aggcccctgt
       61 gttggtcatc tgtgctgata ataaacggcc ctcagggatc cctgagcgaa tctctggctc
      121 caactcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga
      181 ctattactgt caggtttggg acagtagtag taagtgcgta ttattcggag gagggacccg
      241 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000109             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:17446:11606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000109
VERSION     KCVO01000109.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:17446:11606"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..266
                     /note="immunoglobulin light chain variable region"
     V_region        8..266
     V_segment       8..229
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <191..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72138.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       236..266
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           67 a           86 c           88 g           63 t
ORIGIN      
        1 acatgggggg ggagacaacc ttggagataa atatctacac tggtaccacc agaagccagc
       61 gcaggcccct gtgctggtca tctactatga tagtgaccgg ccctcatgga tccctgagcg
      121 attctctggg tccaagtcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg
      181 ggatgaggct gactattact gtcaggtgtg ggacagtaat aatgatcata tctttttcgg
      241 aggagggacc cggctgaccg tcctaggtca gccaaaggct gccccctcgg tcactctctt
      301 cccg
//
LOCUS       KCVO01000110             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:13284:6347
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000110
VERSION     KCVO01000110.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:13284:6347"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72139.1"
                     /translation="DYYCSSYTSSSTWIF"
     J_segment       405..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           88 a          155 c          119 g          111 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 acagtgacat tggtggttat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcactaatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca gtagtacttg gattttcggc ggagggaccc
      421 gtctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000111             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1101:13318:6602
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000111
VERSION     KCVO01000111.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:13318:6602"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72140.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          145 c          125 g          101 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctctgag ctgacacagc
      121 caccctcggt gtcagtgtcc cccggacaga cggccaggat cacctgctct ggaaatgcat
      181 tgccaaaata ctatgcttat tggttccagc agaagccagg ccagtcccct gtggcgatca
      241 tctatgagga caacaaacgg ccctctggga tccctgagag attctctggc tccagctcag
      301 ggacagtggc caccttgact atcagtgggg cccaggtaga ggatgaggct gactactact
      361 gttactcaac agatagcagt ggtactaatg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000112             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:14229:5311
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000112
VERSION     KCVO01000112.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:14229:5311"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72141.1"
                     /translation="DYYCQLWDITSDHWIF"
     J_segment       392..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          149 c          130 g           98 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg cttactgcac aggctctgtg gtctcctatg agctgactca
      121 gcccccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 ccttataaat gaatatgtgc actggtacca acagaaacca ccgcaggccc ctatgctggt
      241 cattcattat gatagtgacc ggccctcagg gatccctgac cgattctctg gctccaaatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcagctg tgggacatta ctagtgatca ttggatattc ggcggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000113             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:11331:7137
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000113
VERSION     KCVO01000113.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11331:7137"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..442
                     /note="immunoglobulin light chain variable region"
     V_region        111..442
     V_segment       111..402
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <366..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72142.1"
                     /translation="DYYCQSSDTSLNDHVLF"
     J_segment       407..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>482
                     /gene="IGLC"
BASE COUNT           96 a          160 c          116 g          110 t
ORIGIN      
        1 acatggggct tcatctgtgg gcacaggagg cagcactcag gacagtctcc agcatggcct
       61 cgtctcctct cctcctcacc cttctcattc actgcacagg gtcctgggcc cagtctgtgc
      121 tgacacagcc gccctcagtg tctggggccc cagggcagag ggtcaccatc tcctgcactg
      181 ggagcagctc caacattgga ggttattatg tatactggta ccagcaactc ccaggaatgg
      241 cccccaaact cctcatctat gacaataata agcgaccctc aggggtttct gaccgattct
      301 ctggctccaa gtctggtacc tcagcctccc tgaccatcac tggactccag actgaggatg
      361 aggctgatta ttactgccaa tcctctgaca ccagcctaaa tgatcatgtg ttattcggtg
      421 gagggacccg gctgaccgtc ctcggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000114             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:15088:8750
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000114
VERSION     KCVO01000114.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:15088:8750"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72143.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       412..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          159 c          129 g          107 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggaccccgg gcagagggtc accatcccgt
      181 gcactgggag cagctccaac attggagctt attttgtata ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctatgaca ataataagcg accctcaggg atttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagcctg
      361 gggatgaggc tgattattac tgcggagcat gggatagcag cctgagtgct cgcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01000115             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:24926:3042
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000115
VERSION     KCVO01000115.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:24926:3042"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72144.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          142 c          138 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag cctctgcggt ctcctatgag ctcactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggaggcaatg
      181 ttggaagtga atatgtccac tggtatcaac agaagccacc gcaggcccct gtggtggtca
      241 tctattataa tagtgaccgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagg agtgatcata gtttattggg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000116             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:20259:19349
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000116
VERSION     KCVO01000116.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20259:19349"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72145.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          156 c          125 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggttccaa cagcacccag gcaaagcccc
      241 caaactcatg atttgtgacg tcagtgatcg gccctcaggg gtctctgctc gcttctctgg
      301 ttccaagtct ggcaatacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000117             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:15595:3132
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000117
VERSION     KCVO01000117.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15595:3132"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72146.1"
                     /translation="DYYCSSYTNSSTWVF"
     J_segment       402..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           87 a          156 c          123 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacacaaa cagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000118             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:2691:12609
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000118
VERSION     KCVO01000118.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:2691:12609"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72147.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           94 a          145 c          124 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctctgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gtcaaaatac tatgcttatt ggttccagca gaagccaggc cagccccctg tggcgatcat
      241 ctatgaggac aacaaacggc cctctgggat ccctgagaga atctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtcgag gatgaagctg actactactg
      361 ttactcaaca gatagcagtg gtactaatgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000119             319 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:7643:12702
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000119
VERSION     KCVO01000119.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 319)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 319)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..319
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:7643:12702"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..281
                     /note="immunoglobulin light chain variable region"
     V_region        9..281
     V_segment       9..244
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <206..>253
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72148.1"
                     /translation="DYYCGAWDSSLSTRLF"
     J_segment       246..281
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        282..>319
                     /gene="IGLC"
BASE COUNT           66 a          100 c           80 g           73 t
ORIGIN      
        1 acatgggctc tcgtgcactg ggagcagctc caacattgga ggttatcttc tatactggta
       61 ccagcagttc ccaggaacag cccccaaact cctcatctat gacaataata agcgaccctc
      121 agggatttct gaccgattct ctggctccaa gtctggtacc tcagcctccc tgaccatcac
      181 tgggctccag cctggggatg aggctgatta ttactgcgga gcatgggata gcagcctgag
      241 tactcgctta ttcggaggag ggacccggct gaccgtccta ggtcagccca aggctgcccc
      301 ctcggtcact ctcttcccg
//
LOCUS       KCVO01000120             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:8179:18364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000120
VERSION     KCVO01000120.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:8179:18364"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72149.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          151 c          125 g          113 t
ORIGIN      
        1 acatgggggg gatctcagga gacagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttttg agcgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcttg atttatgagg tcagttatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattat tgcagctcat acgcaagtag tagtacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000121             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:16867:4509
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000121
VERSION     KCVO01000121.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16867:4509"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72150.1"
                     /translation="DYYCYSIDSSGNRSFF"
     J_segment       390..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           97 a          139 c          123 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac aacaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacaa tcagtggggc ccaggtggag gatgaaactg actactactg
      361 ttattcaata gatagtagtg gtaatcgtag cttcttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000122             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:14999:18168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000122
VERSION     KCVO01000122.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14999:18168"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72151.1"
                     /translation="DYYCYSTRSSGYHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          142 c          125 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ctctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactg tcagtggggc ccaggtgcag gatgaagctg actactactg
      361 ttactcaact cgtagcagtg gttatcatgg cttattcgga ggagggacct ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000123             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:24790:6576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000123
VERSION     KCVO01000123.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24790:6576"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72152.1"
                     /translation="DYYCSSYISSSTWVF"
     J_segment       400..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           88 a          153 c          121 g          111 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg gcctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtaatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaagacgagg
      361 ctgattatta ctgcagctca tatataagta gtagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000124             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:20606:13049
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000124
VERSION     KCVO01000124.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20606:13049"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72153.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           91 a          142 c          126 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagtagtg gtaattatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000125             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:14299:6311
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000125
VERSION     KCVO01000125.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14299:6311"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..405
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72154.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           90 a          155 c          129 g          107 t
ORIGIN      
        1 acatgggggg cttcagctgt gggcacagga ggcagcactc aggacagtct ccagcatggc
       61 ctggtctcct ctcctcctca cccttctcat tcactgcaca gggtcctggg cccagtctgt
      121 gctgacgcag ccgccctcag tgtctggggc gcccgggcag agggtcacca tctcctgcac
      181 tgggagcagc tccaacattg gaggttatta tgtgcagtgg taccagcagc ttccaggaac
      241 ggcccccaaa ctcctcatgt atgaaaataa taagcgaccc tcaggggttt ctgatcgatt
      301 ctctggctcc cagactggta cctcagcctc cctgaccatc actggactcc agtctgagga
      361 tgaggctgat tattactgcc agtcctatga cagcagcctg agtgccgtgt tattcggagt
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01000126             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:15279:8682
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000126
VERSION     KCVO01000126.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15279:8682"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72155.1"
                     /translation="DYYCQVWDSNDDHIFF"
     J_segment       400..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          146 c          136 g           98 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acaggctctg cggtctccta tgagctgact
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 aaccttggag ataaatatct acactggtac caccagaagc cagcgcaggc ccctgtgctg
      241 gtcatctatt atgatagtga ccggccctca tggatccctg agcgattctc tgggtccaag
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag taatgatgat catatctttt tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000127             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:18136:10362
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000127
VERSION     KCVO01000127.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18136:10362"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72156.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          157 c          123 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac tagcacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000128             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:9979:15703
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000128
VERSION     KCVO01000128.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9979:15703"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72157.1"
                     /translation="DYYCQVWDITTDHDVF"
     J_segment       390..426
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          139 c          131 g          101 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatgacc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gttctgcggc ctcctatgaa ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccagggt cacctgtggg ggagacaaca
      181 ttggaagtaa aaatgtgcac tggtaccagc agaagccacc gcaggcccct gttctggtca
      241 tctattatga taccgaacgg ccctcaggga tccctgagcg attctctggc gccaaatcag
      301 ggaacaccgc caccctgatc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacattact actgatcatg atgtgttcgg aagtggcacc aagttgaccg
      421 tcctcggtca gcccaaggct tcccccttgg tcactctgtt cccg
//
LOCUS       KCVO01000129             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:12886:16056
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000129
VERSION     KCVO01000129.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12886:16056"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72158.1"
                     /translation="DYYCYSIDISGNESIF"
     J_segment       395..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          138 c          125 g          107 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacaacc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agtgagcggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaaggtg actactattg
      361 ttactcaata gatatcagtg gtaatgagag cattttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000130             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:6044:10345
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000130
VERSION     KCVO01000130.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:6044:10345"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72159.1"
                     /translation="DYYCYSIDINDNESIF"
     J_segment       395..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           95 a          139 c          122 g          107 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacaacc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agtgagcggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactattg
      361 ttactcaata gatatcaatg ataatgagag cattttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000131             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:10216:7386
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000131
VERSION     KCVO01000131.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10216:7386"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..385
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72160.1"
                     /translation="DYYCQVWDSSGDVFF"
     J_segment       388..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           84 a          142 c          141 g           96 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactgcac agactctgtg gtctcctatg aattgactca
      121 gccacgctca gtgtccgtgt ccccaggaca gacggccagg atcacctgtg ggggagacag
      181 cattggaagt agaagtgtgc agtggtacca gcagaagcca ccgcaggccc ttgtactggt
      241 catctatgct gatagcgaac ggccctcagg gatccctgag cgattctctg gctccaattt
      301 agggaacacc gccaccctga ccatcagcgg cgtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta gtggtgatgt gttcttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000132             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:10329:13374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000132
VERSION     KCVO01000132.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10329:13374"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72161.1"
                     /translation="DYYCYSTDSSTNHGLF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           97 a          144 c          123 g          101 t
ORIGIN      
        1 acatggggct gtgggctcag gaggcagagc tctgggtgtc tcaccatggc ctggattcct
       61 ctcctactcc ccctcctcac tttctgcaca ggctctgcag cctcctatga gctgacacag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgctc tggagatgca
      181 ttgccaaaaa aatatgcttg ttggttccag cagaagccag gccagtcccc tgtaatgatc
      241 atctatgagg acagcaaacg gccccctggg atccctgaga gattctctgg ctccagctca
      301 gggacagtgg ccaccttgac tatcagtggg gcccaggtgg aggatgaagc tgactactac
      361 tgttactcaa cagatagcag tactaatcat ggcttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000133             364 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:21080:15626
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000133
VERSION     KCVO01000133.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 364)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:21080:15626"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    166..326
                     /note="immunoglobulin light chain variable region"
     V_region        166..326
     V_segment       166..292
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <254..>298
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72162.1"
                     /translation="DYYCHSLDTSGNDVF"
     J_segment       296..326
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        327..>364
                     /gene="IGLC"
BASE COUNT           66 a          116 c          100 g           82 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg ggatccctga
      181 gagattctct ggctccagct cagggacagt ggccaccttg actatcagtg gggcccaggt
      241 ggaggatgaa gctgactact actgtcattc attagatacc agtggtaatg atgttttcgg
      301 cggagggacc cggctgaccg tcctagatca gcccaaggct gccccctcgg tcactctctt
      361 cccg
//
LOCUS       KCVO01000134             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:12999:13583
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000134
VERSION     KCVO01000134.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12999:13583"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72163.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       392..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           90 a          143 c          125 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgtagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tttgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagcagtg gtaatcatgt tttcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000135             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:14819:4253
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000135
VERSION     KCVO01000135.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14819:4253"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72164.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           83 a          152 c          124 g          114 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggtttt gagcgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactctt gatttatgag gtcagttatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tgccaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ttgcagctca tacacaagta gtagtacttg ggtattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000136             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:14982:4051
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000136
VERSION     KCVO01000136.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:14982:4051"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72165.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       413..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           92 a          158 c          127 g          110 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcaccctctc
      181 ctgcactggg agcagctcca acattggagg ttattatgtg cagtggtatc agcagcttcc
      241 aggaacggcc cccaaactcc tcatctatga aaataataag cgaccctcag gggtttctga
      301 tcgattctct ggctcccagt ctggtacctc agcctccctg accatcactg gactccagtc
      361 tgaagatgag gctgattatt actgccagtc ctatgacagc agcctgagtg ccgtgttatt
      421 cggaggaggg acccggctaa ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCVO01000137             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:18903:7004
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000137
VERSION     KCVO01000137.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18903:7004"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72166.1"
                     /translation="DYYCSSYAASYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          156 c          119 g          115 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgta ctggaaccag
      181 cagtgacatc ggtacttttg actatgtctc ctggtaccaa caacatccag gcacagcccc
      241 caaactcatg atttttgaag tcagtgagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcagcacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgttcctcat atgcagccag ttacactttt gtgttcggaa gtggcaccaa
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01000138             309 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:12129:19975
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000138
VERSION     KCVO01000138.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 309)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12129:19975"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    73..271
                     /note="immunoglobulin light chain variable region"
     V_region        73..271
     V_segment       73..231
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <196..>243
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72167.1"
                     /translation="DYYCYSTISSGNERIF"
     J_segment       238..271
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        272..>309
                     /gene="IGLC"
BASE COUNT           60 a           96 c           79 g           74 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacagaagcc aggccagtcc cctgtgttga tcatctatga ggacagcaaa
      121 cggccctctg ggatccctga gagattctct ggctccacct tgactatcag tggggcccag
      181 gtggaggatg aggctgacta ctactgttac tcaacaatta gtagtggtaa tgaaaggatc
      241 ttcggtgctg ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact
      301 ctgttcccg
//
LOCUS       KCVO01000139             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:6066:10952
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000139
VERSION     KCVO01000139.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:6066:10952"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72168.1"
                     /translation="DYYCCSFAATYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          158 c          117 g          115 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 caacagtgac atcggtaatt ataactatgt ctcctggtac caacaacatc caggcaccgc
      241 ccccaaactc atgatttatg aggtcagtga gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatttct ggactccagg ctgaggacga
      361 ggctgattat tactgctgct cttttgcagc cacttacact tttgtgttcg gaagtggcac
      421 caagttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01000140             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:5909:9967
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000140
VERSION     KCVO01000140.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:5909:9967"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72169.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           94 a          145 c          123 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctctgacc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaatac tatgcttatt ggttccagca gaagccaggc cagtcccctg tggcgatcat
      241 ctatgaggac aacaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtagag gatgaagctg actactactg
      361 ttactcaaca gatagcagtg gtactaatgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000141             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:6575:14058
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000141
VERSION     KCVO01000141.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:6575:14058"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72170.1"
                     /translation="DYYCYSMDSSTYLGFF"
     J_segment       388..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           94 a          143 c          122 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gcaaaaaaaa tacgcttatt ggttccagca gaagccaggc cagtcccctg tattgatcat
      241 ctatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaatg gatagcagta cttatcttgg cttcttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000142             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:23210:17126
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000142
VERSION     KCVO01000142.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:23210:17126"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72171.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          144 c          125 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc tcctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaaggcaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagttcagg
      301 gacagtggcc accttgacta tcagtcgggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gataacagtg atactcatag gggcttcttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000143             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:20601:2874
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000143
VERSION     KCVO01000143.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:20601:2874"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..443
                     /note="immunoglobulin light chain variable region"
     V_region        119..443
     V_segment       119..405
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72172.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       411..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT          102 a          143 c          130 g          106 t
ORIGIN      
        1 acatggggag ggagcccagc tgtgctgtgg gctcaggagg cagagctctg ggtgtctcac
       61 catggcctgg attcctctcc tactccccct cctcactttc tgcacaggct ctgcagcctc
      121 ctatgagctg acacagccac cctcggtgtc agtgtcccca ggacagacgg ccaggatcac
      181 ctgctctgga gatgcattgc caaaaaaata tgtatattgg ttccagcaga agccaggcca
      241 gtcccctgtg ttgatcatct atgaggacaa caaacggccc tctgggattc ctgagagatt
      301 ctctggctcc agctcaggga cagtggccac cttgactatc agtggggccc aggtggagga
      361 tgaaggtgac tactactgtt actcaagaga tagtagtgaa aatcaaagcg tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCVO01000144             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:17932:11486
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000144
VERSION     KCVO01000144.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17932:11486"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72173.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       391..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           86 a          141 c          139 g           96 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggtct cctatgagct cactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg aggcaatgtt
      181 ggaagtgaat atgtccactg gtatcaacag aagccaccgc aggcccctgt ggtggtcatc
      241 tattataata ctgaccggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 agcaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtaggag tgatcatagt ttattgggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000145             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:10670:13790
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000145
VERSION     KCVO01000145.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10670:13790"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72174.1"
                     /translation="DYYCYSTDTSGYHVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           90 a          138 c          116 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagta
      241 aacggtcctc tgggatccct gagagattct ctggctccag ctcagggaca gtggtcacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagata
      361 ccagtggtta tcatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000146             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:7481:14550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000146
VERSION     KCVO01000146.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7481:14550"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72175.1"
                     /translation="DYYCYSIDSIGSHSVF"
     J_segment       379..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           91 a          140 c          115 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaagtatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaagacgaca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaatagata
      361 gtattggtag tcatagcgtc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000147             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:13323:10511
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000147
VERSION     KCVO01000147.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:13323:10511"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..441
                     /note="immunoglobulin light chain variable region"
     V_region        96..441
     V_segment       96..402
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72176.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       405..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           88 a          159 c          125 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctgctcct ctctcactgc acaggttccc tctcccagcc tgtgctgact cagccaccct
      121 ccctgtctgc atccccggga gcatcggcca gactcccctg caccctgagc agtgacctca
      181 gtgttggtag taaaaacatg tactggtacc agcagaagcc agggagcgct cccaggttat
      241 tcctgtacta ctactccgac tcagacaagc agctgggacc tggggtcccc aatcgagtct
      301 ctggctccaa ggagacctca agtaacacag cgtttttgct catctctggg ctccagcctg
      361 aggacgaggc cgattattac tgtcaggtgt atgacagtac tggagtgttg ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000148             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:16167:7380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000148
VERSION     KCVO01000148.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16167:7380"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..431
                     /note="immunoglobulin light chain variable region"
     V_region        86..431
     V_segment       86..395
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72177.1"
                     /translation="DYHCMIRHNNAYIF"
     J_segment       396..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           94 a          156 c          109 g          110 t
ORIGIN      
        1 acatggggga aaagaggctg tgtccaccat ggcctggact cctctcctcc tcctgctcct
       61 ctctcactgc acaggttccc tctcgcagcc tgtgctgact cagccaacct ccctctcagc
      121 atctcctgga acaacagcca gactcacctg caccttgcgc agtggcatca gtgttggtag
      181 ttacgggatt ttctggtacc aacagaagcc agggagtcct ccccggtatc ttctgaacta
      241 ccacacagac tcagagaagc accagggatc tggagtcccc agccgcttct ctggatccaa
      301 ggatacttcg gccaatgcag gctttttact catctctggg ctccagtctg aggatgaggc
      361 tgactatcac tgtatgattc ggcacaacaa tgcttacatc ttcggtgctg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000149             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:24932:14335
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000149
VERSION     KCVO01000149.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:24932:14335"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72178.1"
                     /translation="DYYCSSYASSSTWIF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          156 c          123 g          105 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcata atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgat catcgctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcag tagcacttgg atattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000150             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:12732:10588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000150
VERSION     KCVO01000150.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12732:10588"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    36..349
                     /note="immunoglobulin light chain variable region"
     V_region        36..349
     V_segment       36..313
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <277..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72179.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       314..349
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>387
                     /gene="IGLC"
BASE COUNT           77 a          120 c          101 g           89 t
ORIGIN      
        1 acatggggga tctcaggagg cagcactctc aggacgtctc cctctgtgtc tgggtctcct
       61 ggacagtcgg tcaccatttc ctgcactgga accagcagtg acattggtga ttataaccgt
      121 gtctcctggt accaacaaca cccaggcaaa gcccccaaac tcatgattta tgaggtcagt
      181 gatcggccct caggggtctc tgatcgcttc tctggttcca agtctggcaa cacggcctcc
      241 ctgatcatct ctgggctcca ggctgaggac gaggctgatt attactgcag ctcatacaca
      301 agcagtagca cttgggtatt cggcggaggg acccggctga ccgtcctagg tcagcccaag
      361 gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000151             309 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:13138:16709
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000151
VERSION     KCVO01000151.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 309)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13138:16709"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..271
                     /note="immunoglobulin light chain variable region"
     V_region        8..271
     V_segment       8..236
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <202..>243
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72180.1"
                     /translation="DYYCFVYYSGTQFF"
     J_segment       241..271
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        272..>309
                     /gene="IGLC"
BASE COUNT           69 a           97 c           80 g           63 t
ORIGIN      
        1 acatggggtg gctccagcac tggagcagtc accagtggta actttccaaa ctggttccag
       61 cagaaacctg gacaagtccc caggggactg atttacaata caaacaacaa acactcctgg
      121 acccctgccc ggttctcagg ctccctcgct gggggcaaag ctgccctgac actgtcagga
      181 gcacagcccg aggacgaggc tgattattac tgcttcgtgt actatagtgg tactcaattc
      241 ttcggaggag ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact
      301 ctcttcccg
//
LOCUS       KCVO01000152             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:7294:8903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000152
VERSION     KCVO01000152.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7294:8903"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72181.1"
                     /translation="DYYCSSYAGSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           84 a          154 c          124 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtaatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgagtc
      361 tgattattac tgcagctcat acgcaggcag tagtacttgg gttttcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000153             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:9337:19923
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000153
VERSION     KCVO01000153.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:9337:19923"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72182.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          144 c          137 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagcctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gtgggagaca
      181 atgttggaag tgaatatgtt cactggtacc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga acgattctct ggctccaaat
      301 cagggagcgc cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000154             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:11634:21899
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000154
VERSION     KCVO01000154.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11634:21899"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72183.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       386..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           85 a          141 c          138 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactgcacag actctgtggt ctcctatgaa ttgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacagca
      181 ttggaagtac aagtgtgcag tggtaccagc agaagccacc gccggccctt gtactggtca
      241 tctatgctga tagcgaacgg ccctcaggga tccctgagcg attctctggc tccaatttag
      301 ggaataccgc caccctgacc atcagcggcg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatgtgt tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000155             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:20877:12746
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000155
VERSION     KCVO01000155.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20877:12746"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72184.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          142 c          138 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgac ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtgtg ggagacaatg
      181 ttggaagtga atatgtgcac tggtaccaac agaagccacc gcaggcccct gtggtggtca
      241 tccattataa tagtgaccgg ccctcaggga tccctgaacg attctctggc tccaaatcag
      301 ggagcgccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatcata gtttattggg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000156             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:8895:8680
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000156
VERSION     KCVO01000156.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:8895:8680"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72185.1"
                     /translation="DYYCAAWDNSLSSPLF"
     J_segment       410..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           94 a          160 c          118 g          110 t
ORIGIN      
        1 acatggggca ccttcagctg cgggtacaga aggcaggact caggataatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gccaccctca acgtctgggg ctcccggaca gagtgtcacc atctcttgct
      181 ctggaagcag ctccaacatt ggaagtaatt atgtatactg gtaccagcag ctcccaggaa
      241 cggcccccaa actcctcatc tattttagta atcagcgacc ctcaggggtc cctgaccgat
      301 tctctgcctc taagtctggc acctcagcct ccctggccat cactggtctc cgatctgagg
      361 atgaggctga ttattactgt gcagcatggg ataacagcct gagcagtccc ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000157             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:23725:17021
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000157
VERSION     KCVO01000157.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:23725:17021"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72186.1"
                     /translation="DYYCSSTDSRDNHRVF"
     J_segment       376..411
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           93 a          140 c          119 g           97 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacgt
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gcagggataa tcatagggta ttcggcggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000158             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1101:22981:11615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000158
VERSION     KCVO01000158.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:22981:11615"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72187.1"
                     /translation="DYYCYSSDSSADYWVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           90 a          139 c          128 g          106 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 tccagaaaaa tatggttatt ggtttcagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggtt ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcatca gatagcagtg ctgattattg ggtgttcggc ggagggaccc ggctgaccgt
      421 cccaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000159             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:12904:10696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000159
VERSION     KCVO01000159.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12904:10696"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72188.1"
                     /translation="DYYCGAWDSSLSGRLF"
     J_segment       412..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          156 c          130 g          108 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtactgac gcagccgccc tcagtgtctg gggaccccgg gcagagggtc accatctcgt
      181 gcactgggag cagctccaac attggaggtt attttgtata ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctatgaca ataataagcg accctcaggg atttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagcctg
      361 gggatgaggc tgattattac tgcggagcat gggatagcag cctgagtggt cgcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01000160             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:2317:14711
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000160
VERSION     KCVO01000160.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:2317:14711"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..389
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72189.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          151 c          121 g          104 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac acagccgccc
      121 tcagtgtctg gggcgcccgg gcagagggtc accatctcct gcactgggag cagttccaac
      181 attggaggtt attatgtgca gtggtaccag cagcttccag gaacggcccc caaactcctc
      241 atgtatgaaa ataataagcg accctcaggg gtttctgatc gattctctgg ctcccagtct
      301 ggtacctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgattattac
      361 tgccagtcct atgacagcag cctgagtgcc gtgttattcg gagcagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000161             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:3045:7498
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000161
VERSION     KCVO01000161.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:3045:7498"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72190.1"
                     /translation="DYYCQVWDSSSDHPIF"
     J_segment       395..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           81 a          146 c          137 g          103 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagtctcttc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac ggacggccag gatcacgtgt gggggagaca
      181 tcgttggaag tgaatatgtt cactggtatc agcagaagtc agcgcaggcc cctgtggtgg
      241 tcatctatta ttattctgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggagcac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactact
      361 actgtcaggt gtgggacagt agtagtgatc atcccatctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01000162             513 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:19907:3876
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000162
VERSION     KCVO01000162.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 513)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 513)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..513
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:19907:3876"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    154..475
                     /note="immunoglobulin light chain variable region"
     V_region        154..475
     V_segment       154..441
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <403..>447
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72191.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       442..475
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        476..>513
                     /gene="IGLC"
BASE COUNT          106 a          155 c          144 g          108 t
ORIGIN      
        1 acatgggggc cccatagggc ctgggaagga ataagagaag cctagggagc ccagctgtgc
       61 tgtgggctca ggaggcagag ctctgggtgt ctcaccatgg cctggattcc tctcctactc
      121 cccctcctca ctttctgcac aggctctgca gcctcctatg agctgacaca gccaccctcg
      181 gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagatgc attgccagaa
      241 aaatttgctt attggttcca acagaagcca ggccagtccc ctgtgctgat catcaatgag
      301 gacagcaaac ggccctctgg gatccctgag agattctctg gctccagctc agggacagtg
      361 gccaccttga ctctcagtgg ggcccaggtg gaggatgaag gtgactacta ctgttcctca
      421 acagatagca gtggtaatta tgtattcggc ggagggaccc ggctgaccgt cctaggtcag
      481 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000163             532 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:10643:9932
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000163
VERSION     KCVO01000163.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 532)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 532)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..532
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10643:9932"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    170..494
                     /note="immunoglobulin light chain variable region"
     V_region        170..494
     V_segment       170..457
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <419..>466
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72192.1"
                     /translation="DYYCQVWDISTDHGVF"
     J_segment       461..494
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        495..>532
                     /gene="IGLC"
BASE COUNT          103 a          161 c          155 g          113 t
ORIGIN      
        1 acatgggggc tgatttgcat cacaggctgc gctctccagc agggggataa gaggcctggg
       61 aggaacctgc ccagcctggg cctcaggagg cagcattgac ggtgcctcag ccatgacctg
      121 gacttttctc ctcctcggcc tccttgctta ctgcacagcc tctgcggcct cctatgagct
      181 gactcagcca ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg
      241 agacaatttt ggaagtaaaa atgtgcactg gtaccggcag aagccaccgc aggcccctgt
      301 tctggtcatc ttatatgatc gcgaacggcc ctcagggatc cctgagcgat tctctggctc
      361 caaatcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga
      421 ctattactgt caggtgtggg acattagtac tgatcatggc gtgttcggaa gtggcaccaa
      481 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01000164             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:18794:12414
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000164
VERSION     KCVO01000164.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18794:12414"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..426
                     /note="immunoglobulin light chain variable region"
     V_region        103..426
     V_segment       103..377
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72193.1"
                     /translation="DYYCQVRDSYSDQWVF"
     J_segment       390..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          146 c          140 g           90 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactgcacag gctctgcggt cgcctatgag ctgactcagc
      121 cacgctcagt ttccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa aagtgtacag tggtaccaac agaagccacc gcaggcccct gtactggtca
      241 tctatggtga tagcgagcgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc attagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgcg ggacagttac agtgatcaat gggtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000165             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:18205:15998
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000165
VERSION     KCVO01000165.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18205:15998"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72194.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       396..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          145 c          133 g           98 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgag ttgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaacc
      181 ttggagataa atatctacac tggtaccacc agaagccagc gcaggcccct gtgctggtca
      241 tctactatga tagtgaccgg ccctcatgga tccctgagcg attctctggg tccaagtcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtaat aatgatcata tctttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000166             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:9094:6365
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000166
VERSION     KCVO01000166.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9094:6365"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72195.1"
                     /translation="DYYCSSYAASYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           82 a          157 c          120 g          116 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gtactggaac
      181 cagcagtgac atcggtactt ttgactatgt ctcctggtac caacaacatc caggcacagc
      241 ccccaaactc atgatttttg aagtcagtga gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcagca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgttcct catatgcagc cagttacact tttgtgttcg gaagtggcac
      421 caagttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01000167             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:12345:9997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000167
VERSION     KCVO01000167.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12345:9997"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..389
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72196.1"
                     /translation="DYYCQSTGSSGNLLF"
     J_segment       391..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          105 a          135 c          124 g           99 t
ORIGIN      
        1 acatgggggc tgtgattcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatgctc agtggttcca gcagaagcca ggccaggccc ctgtgctggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca gttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca acaggcagca gtggtaatct cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000168             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:15299:19319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000168
VERSION     KCVO01000168.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15299:19319"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72197.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       394..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          143 c          138 g           97 t
ORIGIN      
        1 acatggggcc tggcctcggg aagcagcctt ggcggtgcct cagccatggc cgggaccctt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg tctcctatga cctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgt gggagacaat
      181 gttggaagtg aatatgtgca ctggtaccaa cagaagccac cgcaggcccc tgtggtggtc
      241 atccattata atagtgaccg gccctcaggg atccctgaac gattctctgg ctccaaatca
      301 gggagcgccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtgatcat agtttattgg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000169             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:17405:9739
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000169
VERSION     KCVO01000169.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17405:9739"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..428
                     /note="immunoglobulin light chain variable region"
     V_region        105..428
     V_segment       105..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72198.1"
                     /translation="DYFCCSYADTYTFVF"
     J_segment       405..428
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>473
                     /gene="IGLC"
BASE COUNT           83 a          156 c          122 g          112 t
ORIGIN      
        1 acatgggggg gggtctcaga cggcagcgct ctcgggacat ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctcgctc agtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cggtggttat aactttgtct cctggtacca acaacatcca ggcacagccc
      241 ccaaactcat gatttatgag gtcaatcagc ggccctcagg ggtctctgat cgcttctctg
      301 gctcaaagtc tggcaacacg gcctccctga ccgtctccgg ggtccaggct gaggacgagg
      361 ctgattattt ctgctgctca tatgcagaca cctacacttt tgttttcgga agtggcacca
      421 ggttgaccgt cgtcggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01000170             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:2363:15585
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000170
VERSION     KCVO01000170.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:2363:15585"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72199.1"
                     /translation="DYYCQVWDSTSDHPIF"
     J_segment       396..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           81 a          147 c          137 g          103 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acagtctctg cggtctccta tgagctgact
      121 cagccaccct cggtgtcagt gtccccagga cggacggcca ggatcacgtg tgggggagac
      181 atcgttggaa gtgaatatgt tcactggtat cagcagaagt cagcgcaggc ccctgttgtg
      241 gtcatctatt attattctga ccggccctca gggatccctg agcgattctc tggctccaaa
      301 tcagggagca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactac
      361 tactgtcagg tgtgggacag tactagtgat catcccatct tcggtgctgg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCVO01000171             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:16697:2659
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000171
VERSION     KCVO01000171.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:16697:2659"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..252
                     /note="immunoglobulin light chain variable region"
     V_region        9..252
     V_segment       9..217
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <179..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72200.1"
                     /translation="DYYCQVWDSSSDHPIF"
     J_segment       220..252
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        253..>292
                     /gene="IGLC"
BASE COUNT           57 a           83 c           86 g           66 t
ORIGIN      
        1 acatggggtt ggaagtgaat atgtgcactg gtatcagcag aagtcagcgc aggcccctgt
       61 ggtggtcatc tattattata gtgaccggcc ctcagggatc cctgagcgat tctctggctc
      121 caagtcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga
      181 ctattactgt caggtgtggg acagtagtag tgatcatccc atcttcggta ctgggacccg
      241 gctcaccgtc cttggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01000172             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:11171:19106
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000172
VERSION     KCVO01000172.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11171:19106"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..389
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72201.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          151 c          122 g          104 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac gcagccgccc
      121 tcagtgtctg gggcgcccgg gcagagggtc accatctcct gcactgggag cagttccaac
      181 attggaggtt attatgtgca gtggtaccag cagcttccag gaacggcccc caaactcctc
      241 atgtatgaaa ataataagcg accctcaggg gtttctgatc gattctctgg ctcccagtct
      301 ggtacctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgattattac
      361 tgccagtcct atgacagcag cctgagtgcc gtgttattcg gagcagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000173             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:5522:11063
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000173
VERSION     KCVO01000173.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:5522:11063"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72202.1"
                     /translation="DYYFQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          161 c          124 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactttcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000174             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:12206:6569
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000174
VERSION     KCVO01000174.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12206:6569"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72203.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           87 a          156 c          121 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccaa
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa caacacccag gcaaagcccc
      241 caaactcatg atttctgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000175             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:14351:10135
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000175
VERSION     KCVO01000175.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14351:10135"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..434
                     /note="immunoglobulin light chain variable region"
     V_region        106..434
     V_segment       106..400
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72204.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       401..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>474
                     /gene="IGLC"
BASE COUNT           87 a          153 c          124 g          110 t
ORIGIN      
        1 acatgggggt gggatctcag gaggcagcac tctcaggacg tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagtctccct ctgtgtctgg gtctcctgga cagtcggtca ccatttcctg cactggaacc
      181 agcagtgaca ttggtgatta taaccgtgtc tcctggtacc aacagtaccc aggcaaagcc
      241 cccaaagtca tcatttatga ggtcagtgat cggccctcag gggtctctga tcgcttcact
      301 ggtttcaagt ctggcaacac ggcctccctg atcatctctg ggctccaggc tgaggacgag
      361 gctgattatt actgcagctc atacacaagc agtagcactt gggtattcgg cggagggacc
      421 cggctgaccg tccttggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000176             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:21094:5623
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000176
VERSION     KCVO01000176.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21094:5623"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72205.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       388..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          144 c          124 g          101 t
ORIGIN      
        1 acatggggtg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactccccc tcctcacttt ctgcacaggc tctgcagcct cctctgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg aaatgcattg
      181 ccagaatact atgcttattg gttccagcag aagccaggcc agtcccctgt ggcgatcatc
      241 tatgaggaca acaaacggcc ctctgggatc cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cagtggggcc caggtagagg atgaggctga ctactactgt
      361 tactcaacag atagcagtgg tactaatggc ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000177             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:21247:11788
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000177
VERSION     KCVO01000177.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21247:11788"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72206.1"
                     /translation="DYYCQVYDGSAWVF"
     J_segment       408..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           86 a          158 c          127 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ctgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agaagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctcta ctacttctcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacg tcaagtaatg cagcgttttt gatcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacgg tagtgcttgg gtattcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000178             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:8824:13858
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000178
VERSION     KCVO01000178.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:8824:13858"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    152..401
                     /note="immunoglobulin light chain variable region"
     V_region        152..401
     V_segment       152..361
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <323..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72207.1"
                     /translation="DYYCLSYDSSLSAHYMF"
     J_segment       371..401
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>439
                     /gene="IGLC"
BASE COUNT           86 a          147 c          104 g          102 t
ORIGIN      
        1 acatgggggg ggaagctctg cttcagctgt gggcacagga ggcagcactc aggacagtct
       61 ccagcatggc ctcgtctcct ctcctcctca cccttctcat tcactgcaca gggtcctggg
      121 cccagtctgt gctgacacag ccaccctcag tattggaggt gattatgtat cctggtacca
      181 acagctccca ggaacgaccc ccaaactcct catctatcaa aataataagc gaccctcagg
      241 ggtttctgac cgattctctg gctccaagtc tggtccctca gcctccctga ccatcactgg
      301 gctccagact gaggatgagg ctgattacta ctgcctgtcc tatgacagca gcctgagtgc
      361 tcattatatg ttcggtcctg ggacccggct caccgtccta ggtcagccca aggcttcccc
      421 cacggtcact ctgttcccg
//
LOCUS       KCVO01000179             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:13569:22718
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000179
VERSION     KCVO01000179.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:13569:22718"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..430
                     /note="immunoglobulin light chain variable region"
     V_region        107..430
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72208.1"
                     /translation="DYFCCSYADTYTFVF"
     J_segment       407..430
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>475
                     /gene="IGLC"
BASE COUNT           82 a          158 c          122 g          113 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactttgt ctcctggtac caacaacatc caggcacagc
      241 ccccaaactc atgatttatg aggtcaatca gcggccctca ggggtctctg ctcgcttctc
      301 tggctcaaag tctggcaaca cggcctccct gaccgtctcc ggggtccagg ctgaggacga
      361 ggctgattat ttctgctgct catatgcaga cacctacact tttgttttcg gaagtggcac
      421 caggttgacc gtcgtcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01000180             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:8068:19328
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000180
VERSION     KCVO01000180.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:8068:19328"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..453
                     /note="immunoglobulin light chain variable region"
     V_region        120..453
     V_segment       120..413
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72209.1"
                     /translation="DYYCLSYDSSLSAHYIF"
     J_segment       416..453
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           96 a          166 c          119 g          110 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctc gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacacagcca ccctcagtgt ctggggcccc agggcagagg gtcaccatct
      181 cgtgcactgg gagcagctcc agcattggag gtgattatgt ttcctggtac caacagctcc
      241 caggaacgac ccccaaactc ctcatctatc aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtacct cagcctccct gaccatcact ggactccaga
      361 ctgaggatga ggctgattac tactgcctgt cctatgacag cagcctgagt gctcattaca
      421 tcttcggtcc tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca
      481 ctctgttccc g
//
LOCUS       KCVO01000181             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:6796:7906
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000181
VERSION     KCVO01000181.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:6796:7906"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    81..411
                     /note="immunoglobulin light chain variable region"
     V_region        81..411
     V_segment       81..373
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72210.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       375..411
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           83 a          146 c          117 g          103 t
ORIGIN      
        1 acatggggag gacagtctcc agcatggcct ggtctcctct cctcctcacc cttctcattc
       61 actgcacagg gtcctgggcc cagtctgtgc tgacgcagcc gccctcagtg tctggggcgc
      121 ccgggcagag ggtcaccatc tcctgcactg ggagcagttc caacattgga ggttattatg
      181 tgcagtggta ccagcagctt ccaggaacgg cccccaaact cctcatgtat gaaaataata
      241 agcgaccctc aggggtttct gatcgattct ctggctccca gtctggtacc tcagcctccc
      301 tgaccatcac tggactccag tctgaggatg aggctgatta ttactgccag tcctatgaca
      361 gcagcctgag tgccgtgtta ttcggagcag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000182             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:9349:15832
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000182
VERSION     KCVO01000182.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9349:15832"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72211.1"
                     /translation="DYFCSSYADTYTFVF"
     J_segment       404..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           80 a          155 c          120 g          117 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcttgtt ctggaaccag
      181 cagtgacatc ggtagttata actatgtctc ctggtaccaa cagcgtccag gcacagcccc
      241 caatctcatg atttttgagg tcagtaggcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattatttc tgttcctcat atgcagacac ctacactttt gtattcggag gtggcaccaa
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01000183             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:14599:7516
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000183
VERSION     KCVO01000183.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14599:7516"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72212.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          152 c          126 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggagtctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtaatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat atgcaagcag tagcacttgg gttttcggcg gagggacccg
      421 gctgaccgtc ctaggtcagg ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000184             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:13580:18869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000184
VERSION     KCVO01000184.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13580:18869"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..453
                     /note="immunoglobulin light chain variable region"
     V_region        120..453
     V_segment       120..413
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72213.1"
                     /translation="DYYCLSYDTSLSAHYIF"
     J_segment       416..453
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           95 a          165 c          118 g          113 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctc gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacacagcca ccctcagtgt ctggggcccc tgggcagagg gtcaccatct
      181 cgtgcactgg gagcagctcc aacattggaa gtatttatgt atcctggtac cagcagttcc
      241 caggaacgac ccccaaactc ctcatctatc aagataataa gcgaccctca ggggtttctg
      301 accgcttctc tggctccaag tctggtacct cagcctccct gaccatcact gggctccaga
      361 ctgaagatga ggctgattat tactgcctgt cctatgacac cagcctgagt gctcattaca
      421 tcttcggtgc tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca
      481 ctctgttccc g
//
LOCUS       KCVO01000185             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:13023:15096
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000185
VERSION     KCVO01000185.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13023:15096"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..447
                     /note="immunoglobulin light chain variable region"
     V_region        126..447
     V_segment       126..413
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72214.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       414..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           97 a          148 c          134 g          106 t
ORIGIN      
        1 acatggggga agcctaggga gcccagctgt gctgtgggct caggaggcag agctctgggt
       61 gtctcaccat ggcctggatt cctctcctac tccccctcct cactttctgc acaggctctg
      121 cagcctccta tgagctgaca cagccaccct cggtgtcagt gtccccagga cagacggcca
      181 ggatcacctg ctctggagat gcattgccag aaaaatatgc ttattggttc cagcagaagc
      241 caggccagtc ccctgtgttg atcatcaatg aggacagcaa acggccctct tggatccctg
      301 ggagattctc tggctccagc tcagggacag tggccacctt gactctcagt ggggcccagg
      361 tggaggatga agctgactac tactgttcct caacagatag tagtggaaat tatgtattcg
      421 gcggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01000186             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:22563:16321
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000186
VERSION     KCVO01000186.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:22563:16321"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72215.1"
                     /translation="DYYCQVWDSSSKYAIF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          148 c          135 g           88 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcgacc tcctatgagg tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaga aatgtccact ggtaccagca gaagccaccg caggcccctg ttctggtcat
      241 ctatgctgat gccaaacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatacgc gatattcggc ggagggaccc ggctgaccgt
      421 cctaggtcaa cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000187             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:11645:15745
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000187
VERSION     KCVO01000187.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11645:15745"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..406
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72216.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          156 c          128 g          109 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gtgtctgggg cgcccgggca gagggtcacc atctcctgca
      181 ctgggagcag ttccaacatt ggaggttatt atgtgcagtg gtaccagcag cttccaggaa
      241 cggcccccaa actcctcatg tatgaaaata ataagcgacc ctcaggggtt tctgatcgat
      301 tctctggctc ccagtctggt acctcagcct ccctgaccat cactggactc cagtctgagg
      361 atgaggctga ttattactgc cagtcctatg acagcagcct gagtgccgtg ttattcggag
      421 cagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000188             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:19345:14042
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000188
VERSION     KCVO01000188.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19345:14042"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72217.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       402..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           86 a          157 c          123 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggc cacaggatgc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt atcaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaatga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacacaag cagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000189             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:3178:16446
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000189
VERSION     KCVO01000189.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:3178:16446"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..306
                     /note="immunoglobulin light chain variable region"
     V_region        87..306
     V_segment       87..268
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72218.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       274..306
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           70 a          102 c           95 g           77 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagc agaagccagg ccagtcccct gtgttgatca
      121 tctatgagga caacaaacgg ccctctggga ttcctgagag attctctggc tccagctcag
      181 ggacagtggc caccttgact atcagtgggg cccaggtgga ggatgaaggt gactactact
      241 gttactcaag agatagtagt gaaaatcaaa gcgtcttcgg tgctgggacc cggctcagcg
      301 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCVO01000190             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:5587:9998
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000190
VERSION     KCVO01000190.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:5587:9998"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72219.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       378..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           88 a          141 c          117 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatttg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gcagtggtaa tcatgttttc ggcggaggga cctggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000191             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:22202:5605
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000191
VERSION     KCVO01000191.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:22202:5605"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72220.1"
                     /translation="DYYCQVWDSGHDHVFF"
     J_segment       400..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           87 a          146 c          139 g           96 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acaggctctg cggtctccta tgagctgact
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 aaccttggag ataaatatgt acactggtac cagcagaagc cagcgcaggc ccctgtgctg
      241 gtcatctact atgatagtga ccggccctca cggatcactg agcgattctc tgggtccaaa
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag tggtcatgat catgtctttt tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000192             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:24095:6643
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000192
VERSION     KCVO01000192.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:24095:6643"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..399
                     /gene="IGLV10-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72221.1"
                     /translation="DYYCSAWDSSLSVVLF"
     J_segment       405..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT          105 a          160 c          125 g           86 t
ORIGIN      
        1 acatggggct ccaaagcaga gcttcggcaa gcacagtggg aatccgcacc atgccctggg
       61 ctctgctcct cctgaccctc ctcactcact ctgcagtgcc agtggtccag gcagggctga
      121 ctcagccacc ctcagtgtcc aagggcttga gacagacggc cacgctcacc tgcactggaa
      181 acagcaacaa tgttggcaac cagggagcag gttggctgca gcagcaccag ggccaccctc
      241 ccaaactgct gtcctacagg aataacaacc ggccctcggg gatctcagag agattctctg
      301 catccaggtc aggaaacaca gcctccctga ccatcaccgg actccaacct gaggatgagg
      361 ctgactatta ctgctcagca tgggacagca gcctcagtgt tgttttattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000193             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1101:23976:10518
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000193
VERSION     KCVO01000193.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:23976:10518"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..240
                     /note="immunoglobulin light chain variable region"
     V_region        9..240
     V_segment       9..206
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <170..>214
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72222.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       207..240
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        241..>280
                     /gene="IGLC"
BASE COUNT           53 a           90 c           74 g           63 t
ORIGIN      
        1 acatggggac cgtgtctcct ggtaccaaca gcacccaggc aaagccccca aactcatgat
       61 ttatgaggtc agtgatcggc cctcaggggt ctctgatcgc ttctctggtt ccaagtctgg
      121 caacacggcc tccctgatca tctctgggct ccaggctgag gacgaggctg attattactg
      181 cagctcatac actagcagta gcacttgggt attcggcgga gggacccggc tgaccgtcct
      241 tggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000194             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:15979:12271
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000194
VERSION     KCVO01000194.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15979:12271"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72223.1"
                     /translation="DYYCSSTDTSGNHVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          145 c          123 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgaaaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gataccagtg gtaatcatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000195             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:18501:11554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000195
VERSION     KCVO01000195.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18501:11554"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72224.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          155 c          129 g          107 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcctcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcac ctccaacatc gggagtaaca gtgtgtcctg gtacctgcag ctcccagaaa
      241 cggctcccaa actcctcatc tattataatg atcggcgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc ccgtcagcct ccctggccat cagtgggctc gagaccgaag
      361 atgaggctga ttattactgc gcagtatggg atgacagcct gagcggtgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000196             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:20228:10732
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000196
VERSION     KCVO01000196.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20228:10732"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..382
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72225.1"
                     /translation="DYYCQSTDSSGYIF"
     J_segment       383..419
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT          102 a          134 c          118 g          103 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgtggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 gacaaaaaat tatgctcagt ggttccagca gaagccaggc caggcccctg tgctgctgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagtt ccagttcagg
      301 gacaacagtt accttgacca tcagtcgggc ccaggtagaa gatgaggctg actattattg
      361 tcaatcaaca gacagcagtg gttacatctt cggtgctggg acccggctca ccgtcctagg
      421 tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01000197             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:13327:3128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000197
VERSION     KCVO01000197.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:13327:3128"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72226.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       396..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          141 c          139 g           98 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gtctcctatg acctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 tgttggaagt gaatttgtac actggtacca acagaagcca gcgcaggccc ctgtggtggt
      241 cattcattat aatagtgacc ggccctcagg gatccctgaa cgattctctg gctccaaatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta gtagtgatca ttgtgtattg ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000198             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:20489:19566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000198
VERSION     KCVO01000198.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20489:19566"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..447
                     /note="immunoglobulin light chain variable region"
     V_region        118..447
     V_segment       118..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72227.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       412..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>486
                     /gene="IGLC"
BASE COUNT           92 a          155 c          129 g          110 t
ORIGIN      
        1 acatgggggg ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccatt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggaggt tattatgtgc agtggtacca gcaacttcca
      241 ggaacggccc ccaaagttct catctatgaa aataataagc gaccctcagg ggtttctgat
      301 cgattctctg gctcccagtc tggtacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gcctgagtgc cgtgttattc
      421 ggaggaggga cccggctgac cgtcctaagt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01000199             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:9595:10861
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000199
VERSION     KCVO01000199.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:9595:10861"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72228.1"
                     /translation="DYYCQVWGSSTKYMSF"
     J_segment       394..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          151 c          130 g           91 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagc ctctgcgacc tcctatgagt tgacgcagcc
      121 accctcggtg tcagcggccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaaattac aatgtgcact ggtaccagca gaagccaccc caggcccctc tactggtcat
      241 ttttgctgat agcaagcggc cctctgggat ccctgaccga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcagggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg ggcagtagta ctaaatacat gtcattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000200             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:11887:5131
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000200
VERSION     KCVO01000200.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11887:5131"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..431
                     /note="immunoglobulin light chain variable region"
     V_region        104..431
     V_segment       104..387
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72229.1"
                     /translation="DYYCSSYAGTNRVF"
     J_segment       396..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           84 a          156 c          123 g          106 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc ctctcctgca ctggaaccag
      181 cagtgatatt gggtatttta atgctgtgtc ttggtaccaa caacatccag gcaaggcccc
      241 caaactcatg atttatgagg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcac caacagggtg ttcggcggag ggacccgcct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000201             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:13268:21894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000201
VERSION     KCVO01000201.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13268:21894"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..372
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72230.1"
                     /translation="DYYCYSMDSSTYLGFF"
     J_segment       374..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           91 a          145 c          113 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcactgcca aaaaaatacg
      181 cttattggtt ccagcagaag ccaggccagt cccccgtatt gatcatctat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcac tggggcccag gtggaggatg aagctgacta ctactgttac tcaatggata
      361 gcagtactta tcttggcttc ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000202             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:21465:2096
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000202
VERSION     KCVO01000202.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:21465:2096"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72231.1"
                     /translation="DYYCSAWDNSLSGYIF"
     J_segment       408..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           88 a          153 c          129 g          113 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctctccttct cactctgctg gttcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agcatctggg gcccccgggc agagggtcac catctcgtgc
      181 actgggagca gctccaacat tggaggttat tctgtatcct ggtaccggca acgcccagga
      241 gcggtcccca aactcctcat ctttgaaaat aataagcgac cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg tgtctcagcc tccctatgca tcactggact ccagtctgag
      361 gatgaggctg attattactg ctcagcttgg gataacagcc tgagtggtta catcttcggt
      421 gctgggaccc gagtcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCVO01000203             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:14780:7448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000203
VERSION     KCVO01000203.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14780:7448"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72232.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          142 c          137 g           98 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgag ctcactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggaggcaatg
      181 ttggaagtga atatgtccac tggtatcaac agaagccacc gcaggcccct gtggtggtca
      241 tctattataa tactgaccgg ccctcaggga tccctgagcg attctctgtc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagg agtgatcata gtttattggg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000204             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:20531:4236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000204
VERSION     KCVO01000204.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:20531:4236"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72233.1"
                     /translation="DYYCSSTDTSGNHVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           92 a          145 c          124 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaaggtg actactactg
      361 ttcctcaaca gataccagtg gtaatcatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000205             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:19572:18312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000205
VERSION     KCVO01000205.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19572:18312"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72234.1"
                     /translation="DYYCCSYVDTYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           83 a          157 c          119 g          116 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagctgtgac atcggtactt ataactatgt ctcctggtac caacagcatc caggcacagc
      241 ccccaaactc ataatttttg aggtcagtga gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgttgct catatgtaga cacctacact tttgtgtttg gacgtggcac
      421 cagattgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01000206             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:6149:15781
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000206
VERSION     KCVO01000206.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6149:15781"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72235.1"
                     /translation="DYYCSSTDSSGSYVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           91 a          142 c          126 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgtagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tactgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gacagtagtg gtagttatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000207             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:19679:5761
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000207
VERSION     KCVO01000207.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19679:5761"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72236.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           91 a          142 c          117 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatctcct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag gcaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ttcagggaca gtggccacct
      301 tgactatcag tcgggcccag gtggaggatg aagctgacta ctactgttac tcaacagata
      361 acagtgatac tcataggggc ttcttcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000208             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:22227:11701
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000208
VERSION     KCVO01000208.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:22227:11701"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..424
                     /note="immunoglobulin light chain variable region"
     V_region        94..424
     V_segment       94..385
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72237.1"
                     /translation="DYYCSAWDNGLTAYIF"
     J_segment       387..424
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           90 a          148 c          120 g          104 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tctccttctc
       61 actctgctgg ttcactgcac agggtcctgg gcccagtctg tgctgacgca gccgccctca
      121 gtgtctgggg cgcccgggca gagggtcacc atctcctgca ctgggagcag ctccaacatt
      181 ggaggttatt atgtacagtg gtaccagcag cttccaggaa cggcccccaa actcctcatc
      241 tttgaaaata ataagcgacc ctcagggatt tctgaccgat tctctgggtc caagtctggt
      301 acctcagcct ccctaaccat cactggactc cagtccgagg atgaggctga ttattactgc
      361 tcagcatggg ataacggtct gactgcttac atcttcggtg ctgggacccg gctcaccgcc
      421 ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01000209             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:10044:16664
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000209
VERSION     KCVO01000209.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10044:16664"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72238.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       379..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           91 a          141 c          115 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaagtatg
      181 cttattggtt ccagcagaag ccaggccagt cccctctgct gatcatctat gaagacgaca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaatagata
      361 gtagtggtag tcatagcgtc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000210             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:20185:15209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000210
VERSION     KCVO01000210.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20185:15209"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72239.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       375..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           93 a          141 c          116 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctcccactcc
       61 tcactttctg cacaggctct gcagcctcct ctgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgtca aaatactatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtggc gatcatctat gaggacaaca
      241 aacggccctc tgggatccct gagagaatct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtcgaggatg aagctgacta ctactgttac tcaacagata
      361 gcagtggtac taatggctta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000211             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:8958:19311
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000211
VERSION     KCVO01000211.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8958:19311"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72240.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          157 c          124 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtggtt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcactaa tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacgcaag cagtagcact tgggttttcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000212             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:8617:12838
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000212
VERSION     KCVO01000212.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8617:12838"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72241.1"
                     /translation="DYYCGAWDSSLSTRLF"
     J_segment       413..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           92 a          157 c          129 g          108 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggaccccg ggcagagggt caccatctcg
      181 tgcactggga gcagctccaa cattggaggt tattttgtat actggtacca gcagttccca
      241 ggaacagccc ccaaactcct catctatgac aataataagc gaccctcagg gatttctgac
      301 cgattctctg gctccaagtc tggtacctca gcctccctga ccatcactgg gctccagcct
      361 ggggatgagg ctgattatta ctgcggagca tgggatagca gcctgagtac tcgcttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01000213             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:21594:9957
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000213
VERSION     KCVO01000213.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:21594:9957"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72242.1"
                     /translation="DYHCFSTDSSGNQRGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           94 a          142 c          125 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgacgac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcatg
      301 gacagtggcc accttgacta tcattggggc ccaggtggag gatgaaggtg actaccactg
      361 tttctcaaca gatagtagtg gtaatcaaag gggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000214             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:12519:20931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000214
VERSION     KCVO01000214.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12519:20931"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72243.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          156 c          123 g          108 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctatgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacacaag cagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000215             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:8126:9143
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000215
VERSION     KCVO01000215.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:8126:9143"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72244.1"
                     /translation="DYYCYSSDSSADYWVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           90 a          141 c          128 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggtt ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcatca gatagcagtg ctgattattg ggtgttcggc ggagggaccc ggctgaccgt
      421 cccaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000216             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:11489:19094
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000216
VERSION     KCVO01000216.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11489:19094"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..368
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72245.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           95 a          142 c          114 g           95 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggta ccagcagaaa ccaggccagt cccctatgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gaaagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcac tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 acagtggtca gggctcattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000217             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:13747:13605
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000217
VERSION     KCVO01000217.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13747:13605"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72246.1"
                     /translation="DYYCSSYASSITWIF"
     J_segment       404..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          154 c          123 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtgtc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagttatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcag tatcacttgg attttcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000218             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:12547:13999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000218
VERSION     KCVO01000218.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12547:13999"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..422
                     /note="immunoglobulin light chain variable region"
     V_region        100..422
     V_segment       100..381
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72247.1"
                     /translation="DYYCQVWDSSSDHWVF"
     J_segment       387..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>462
                     /gene="IGLC"
BASE COUNT           83 a          141 c          142 g           96 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctgcacagac tctgcggtct cctatgagct gactcagcca
      121 cgctcagtgt ccgtgtcccc aggacagacg gcccgggtca cctgtggggg agacaacatt
      181 ggaagtaaaa gtgtgcagtg gttccagcag aagccaccgc aggcccctgt gttggtcatt
      241 tatggtgata gcgaacggcc ctcagggatc cctgagcgat tctctggttc caactcaggg
      301 aacattgcca ccctgaccat cagcggggtc gaggccggga atgaggctga ctattactgt
      361 caggtgtggg acagtagtag tgatcattgg gtattcggcg gagggacccg gctgaccgtc
      421 ctcggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000219             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:8568:12423
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000219
VERSION     KCVO01000219.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8568:12423"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72248.1"
                     /translation="DYYCQVWDSRTKSVLF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          140 c          141 g           94 t
ORIGIN      
        1 acatggggtg actttgggaa gcagccttgg cggtgcctca gccatggccg ggacccttct
       61 cctcctcggc ctccttgctc actgcacagg ctctgcggcc tcctatgagc tgactcagcc
      121 accctcggtg tcggtgtccc caggacagac agccagggtc acctgtgggg gagaggacat
      181 tggaagaaaa agtgtgaact ggtaccagca gaggccaatg caggcccctg tgttggtcat
      241 ccatggtgat tacgaaaggc cctcagggat ccctgagcgc ttctctggct ccaattcagg
      301 gaacactgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagaa ctaaatccgt gttattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000220             306 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:13957:14885
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000220
VERSION     KCVO01000220.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 306)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13957:14885"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..267
                     /note="immunoglobulin light chain variable region"
     V_region        7..267
     V_segment       7..230
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <193..>240
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72249.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       232..267
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        268..>306
                     /gene="IGLC"
BASE COUNT           66 a           91 c           77 g           72 t
ORIGIN      
        1 acatggggga gcagctccaa cattggaggt tattatgtgc agtggtacca gcaacttcca
       61 ggaacggccc ccaaagttct catctatgaa aataataagc gaccctcagg ggtttctgat
      121 cgattctctg gctcccagtc tggtacctca gcctccctga ccatcactgg actccagtct
      181 gaggatgagg ctgattatta ctgccagtcc tatgacagca gcctgagtgc cgtgttattc
      241 ggaggaggga cccggctgac cgtcctaagt cagcccaagg ctgccccctc ggtcactctc
      301 ttcccg
//
LOCUS       KCVO01000221             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:14410:9707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000221
VERSION     KCVO01000221.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14410:9707"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72250.1"
                     /translation="DYYCSSTDTSGNHVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           91 a          144 c          123 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tttgcttatt ggttccagca gaagtcaggc cagtcccctg tgttgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtgcggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gataccagtg gtaatcatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000222             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:22217:9547
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000222
VERSION     KCVO01000222.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:22217:9547"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..449
                     /note="immunoglobulin light chain variable region"
     V_region        118..449
     V_segment       118..409
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <373..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72251.1"
                     /translation="DYYCQSSDTSLNDHVLF"
     J_segment       414..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>489
                     /gene="IGLC"
BASE COUNT           98 a          162 c          118 g          111 t
ORIGIN      
        1 acatggggag ctctgcttca tctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctcgt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtactga cacagccgcc ctcagtgtct ggggccccag ggcagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggaggt tattatgtat actggtacca gcaactccca
      241 ggaatggccc ccaaactcct catctatgac aataataagc gaccctcagg ggtttctgac
      301 cgattctctg gctccaagtc tggtacctca gcctccctga ccatcactgg gctccagact
      361 gaggatgagg ctgattatta ctgccaatcc tctgacacca gcctaaatga tcatgtgtta
      421 ttcggaggag ggacccggct gaccgtcctc ggtcagccca aggctgcccc ctcggtcact
      481 ctcttcccg
//
LOCUS       KCVO01000223             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:23442:2903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000223
VERSION     KCVO01000223.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:23442:2903"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72252.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           87 a          157 c          132 g          110 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccctctcc
      181 tgcactggga gcagctccaa cattggaggt tattatgtgc agtggtacca gcagcttcca
      241 ggaacggccc ccaaactcct catctatgaa aataataagc gaccctcagg ggtttctgat
      301 cggttctctg gctcccagtc tggttcgtca gcctccctga ccgtcaatgg actccagtct
      361 gaagatgagg ctgattatta ctgccagtcc tatgacagca gcctgagtgc cgtgttgttc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01000224             405 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:11879:15743
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000224
VERSION     KCVO01000224.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 405)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:11879:15743"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    43..367
                     /note="immunoglobulin light chain variable region"
     V_region        43..367
     V_segment       43..330
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <292..>339
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72253.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       331..367
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        368..>405
                     /gene="IGLC"
BASE COUNT           85 a          127 c          106 g           87 t
ORIGIN      
        1 acatgggtcc ccctcctcac tttctgcaca ggctctgcag cctcctctga gctgacacag
       61 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgctc tggaaatgca
      121 ttgccagaat actatgctta ttggttccag cagaagccag gccagtcccc tgtggcgatc
      181 atctatgagg acaacaaacg gccctctggg atccctgaga gattctctgg ctccagctca
      241 gggacagtgg ccaccttgac tatcagtggg gcccaggtag aggatgaggc tgactactac
      301 tgttactcaa cagatagcag tggtactaat ggcttattcg gaggagggac ccggctgacc
      361 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000225             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:3110:11874
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000225
VERSION     KCVO01000225.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:3110:11874"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..401
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72254.1"
                     /translation="DYYCSSYADTYTFVF"
     J_segment       402..436
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           79 a          161 c          121 g          113 t
ORIGIN      
        1 acatgggggt ggggtctcag acggcagcgc tctcgggaca tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagcctcgct cagtgtctgg gtctcctgga cagtcggtca ccatctcctg cactggcacc
      181 agcagtgaca tcggtggtta taactttgtc tcctggtacc aacaccatcc aggcacagcc
      241 cccaaactcg tgatttatga ggtcactcag cggccctcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcagcgc ggcctccctg accatctctg ggctccaggc tgaggacgag
      361 gctgattatt actgctcctc atatgcagac acttacactt ttgtgttcgg aagtggcacc
      421 aagttgaccg tcctcggtca gcccaaggct tcccccttgg tcactctgtt cccg
//
LOCUS       KCVO01000226             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:12290:2088
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000226
VERSION     KCVO01000226.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12290:2088"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72255.1"
                     /translation="DYYCSSTDSRDNHRVF"
     J_segment       376..411
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           92 a          141 c          119 g           97 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca caaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacgt
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gcagggataa tcatagggta ttcggcggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000227             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:20260:19756
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000227
VERSION     KCVO01000227.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20260:19756"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72256.1"
                     /translation="DYYCYSSDSSADYWVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           91 a          141 c          127 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagac
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tcttgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggtt ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcatca gatagcagtg ctgattattg ggtgttcggc ggagggaccc ggctgaccgt
      421 cccaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000228             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:17531:12106
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000228
VERSION     KCVO01000228.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17531:12106"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72257.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          154 c          123 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtaatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat atgcaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000229             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:21079:14423
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000229
VERSION     KCVO01000229.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21079:14423"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..402
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72258.1"
                     /translation="DYYCQVYDSAGVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           86 a          161 c          127 g          109 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt tctactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtgctggagt gttgttcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01000230             422 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:15148:13608
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000230
VERSION     KCVO01000230.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 422)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 422)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:15148:13608"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    63..384
                     /note="immunoglobulin light chain variable region"
     V_region        63..384
     V_segment       63..347
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <312..>356
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72259.1"
                     /translation="DYYCYSADSSGNGLF"
     J_segment       348..384
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        385..>422
                     /gene="IGLC"
BASE COUNT           89 a          130 c          111 g           92 t
ORIGIN      
        1 acatgggggc ctggattcct ctcctactcc ccatcctcac tttctgcaca ggctctgcag
       61 cctcctatga gctgacacag ccaccctcgt tgtcagtgtc cccaggacag acggccagga
      121 tcacctgctc tggagatgca ttgccagaaa aatatgcgta ttggtatcag cagaaaccag
      181 gccagtcccc tgtgcatatc atctatgagg acagcaagcg gccctctggg atccctgaga
      241 gattctctgg ctccagctca gggacagtgg ccaccttgac tatcagtggg gcccaggtgg
      301 aggatgaagc tgactactac tgttactcag cagacagtag tggtaatggc ttattcggag
      361 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      421 cg
//
LOCUS       KCVO01000231             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:11065:17128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000231
VERSION     KCVO01000231.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11065:17128"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72260.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          156 c          128 g          107 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcctcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcac ctccaacatc gggagtaaca gtgtgtcctg gtacctgcag ctcccagaaa
      241 cggctcccaa actcctcatc tattataatg atcggcgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc ccgtcagcct ccctggccat cagtgggctc gagaccgaag
      361 atgaggctga ttattactgc gcagtatggg atgacagcct gagcggtgtg ttattcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000232             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:12771:5592
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000232
VERSION     KCVO01000232.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12771:5592"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72261.1"
                     /translation="DYYCQVWDSSSKCVLF"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           92 a          143 c          138 g           94 t
ORIGIN      
        1 acatgggggt ctgggcctca ggaggcagca ttgacggtgc ctcagccatg gcctggaccc
       61 ttctcctcct cggcctcctc gctcactgca caggctctgc ggcctcctat gatctgactc
      121 agccaccctc ggtgtcagcg gcctcaggac agacggccag gatcacctgt gggggagaca
      181 atattggaag taaaaatgtg cactggtacc agcagaagcc agcgcaggcc cctgtgttgg
      241 tcatctgtgc tgataataaa cggccctcag ggatccctga gcgaatctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt ttgggacagt agtagtaagt gcgtattatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000233             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:8329:3858
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000233
VERSION     KCVO01000233.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:8329:3858"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..409
                     /note="immunoglobulin light chain variable region"
     V_region        88..409
     V_segment       88..369
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72262.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       372..409
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           91 a          127 c          130 g           99 t
ORIGIN      
        1 acatggggac agatctcctc cagcagcagc tcctgactct gctgatttgc atcatgggct
       61 gttctcttca gcaaagactc tgtggtctcc tatgaattga ctcagccacg ctcagtgtcc
      121 gtgtccccag gacagacggc caggatcacc tgtgggggag acagcattgg aagtagaagt
      181 gtgcagtggt atcagcagaa gccaccgcag gcccttgtac tggtcatcta tgctgatagc
      241 gaacggccct cagggatccc tgagcgattc tctggctcca atttagggaa caccgccacc
      301 ctgaccatca gcggcgtcga ggccggggat gaggctgact attactgtca ggtgtgggac
      361 agtagtagtg atgtgttatt cggaggaggg acccggctga ccgtcctagg tcagcccaag
      421 gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000234             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:23933:12346
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000234
VERSION     KCVO01000234.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:23933:12346"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..445
                     /note="immunoglobulin light chain variable region"
     V_region        112..445
     V_segment       112..403
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72263.1"
                     /translation="DYFCSVWDSSLTIYIF"
     J_segment       408..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           87 a          157 c          126 g          113 t
ORIGIN      
        1 atgggggctc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc tccttctcac tctgctggtt cactgcacag ggtccggggc ccagcctgtg
      121 ctgacgcagc cgccctcagc atctggggcc cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacatcgg ggcgggttat tctgtatcct ggtatcagca gttcccagga
      241 acagccccca aactcctcat ctatgaaaat aataagcgac cctcaggggt ttctgaccga
      301 ttctctggct ccaagtctgg tacctcagcc tccctgacta tcactggact ccaatctgag
      361 gatgaggctg attatttctg ctctgtctgg gatagcagcc tgactattta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCVO01000235             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:20360:20162
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000235
VERSION     KCVO01000235.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20360:20162"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72264.1"
                     /translation="DYYCAAWDDSLSSPLF"
     J_segment       393..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          148 c          116 g          110 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagtttcaac
      181 attggaagta attatgtaaa ctggtaccag cagctcccag gaacggcctc caaactcctc
      241 atctatttta gtaatcagcg gccctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcat gggatgatag tctgagcagt cccttattcg gaggagggac ccagctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000236             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:20118:21850
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000236
VERSION     KCVO01000236.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20118:21850"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72265.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       397..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          143 c          139 g           95 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagactctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaag tgaatacgtg cactggtacc aacagaaacc agcgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgtgtatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000237             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:17768:15168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000237
VERSION     KCVO01000237.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:17768:15168"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72266.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          152 c          121 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcctc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cacctccaac
      181 atcggaagta acagtgtgtc ctggtacctg cagctcccag aaacggctcc caaactcctc
      241 atctattcta atgatcggcg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcccgtcag cctccctggc catcagtggg ctcgagaccg aagatgaggc tgattattac
      361 tgcgcagtat gggatgatag cctgagcggt gtgttattcg gaggagggac ccgactgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000238             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:8376:15043
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000238
VERSION     KCVO01000238.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:8376:15043"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72267.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           86 a          155 c          124 g          108 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca gtagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000239             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:12752:8866
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000239
VERSION     KCVO01000239.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12752:8866"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..384
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72268.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       388..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           97 a          144 c          123 g           98 t
ORIGIN      
        1 acatgggggt gtgggctcag gaggcagagc tctgggtgtc tcaccatggc ctggattcct
       61 ctcctactcc ccatcctcac tttctgcaca ggctctgcag cctcctatga gctgacacag
      121 ccaccctcgt tgtcagtgtc cccaggacag acggccagga tcacctgctc tggagatgca
      181 ttgccagaaa aatatgctta ttggtaccag cagaaaccag gccagtcccc tatgctgatc
      241 atctatgagg acagcaaacg gccctctggg atccctgaaa gattctctgg ctccagctca
      301 gggacagtgg ccaccttgac tatcactggg gcccaggtgg aggatgaagc tgactactac
      361 tgttactcag cagacaacag tggtcagggc tcattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000240             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:12532:14919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000240
VERSION     KCVO01000240.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12532:14919"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72269.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          143 c          138 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt atgggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga acgattctct ggctccaaat
      301 cagggagcgc cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000241             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:14185:22730
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000241
VERSION     KCVO01000241.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14185:22730"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72270.1"
                     /translation="DYYCYSADSSGNGLF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           94 a          140 c          126 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcgtatt ggtatcagca gaaaccaggc cagtcccctg tgcatatcat
      241 ctatgaggac agcaagcggc cctctgggat ccctgcgaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtaatggctt attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000242             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:20777:5028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000242
VERSION     KCVO01000242.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20777:5028"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72271.1"
                     /translation="EYYCSSYADIYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           84 a          163 c          119 g          109 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tggcctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcacgggcac
      181 cagcagtgac atcggtggtt acaactttgt ctcctggtac caacaccatc cagacacagc
      241 ccccaaactc gtgatttctg aggtcactca gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgaatat tactgcagtt catatgcaga catctacaca tttgtgttcg gaagtggcac
      421 caagttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01000243             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:5643:6252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000243
VERSION     KCVO01000243.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5643:6252"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72272.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       407..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           88 a          157 c          129 g          106 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggac cccgggcaga aggtcaccat ctcgtgcact
      181 gggagcagct ccaacattgg aggttatttt gtgtactggt accagcagtt cccaggaaca
      241 gccccccaac tcctcatcta tgacaataat aagcgaccct cagggatttc tgaccgattc
      301 tctggctcca agtctggtac ctcagcctcc ctgaccatca ctgggctcca gcctggggat
      361 gaggctgatt attactgcgg cgcatgggat agcagcctga gtgctcgctt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000244             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:17389:10552
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000244
VERSION     KCVO01000244.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17389:10552"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72273.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          160 c          125 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagtatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000245             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:14255:9560
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000245
VERSION     KCVO01000245.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14255:9560"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..395
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72274.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       396..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           86 a          160 c          116 g          107 t
ORIGIN      
        1 acatggggat ctcaggaggc agcactctca ggacgtctcc accatggcct gggctctgct
       61 cctcctcacc ctcctcactc agggcacagg atcctgggct caggctgccc tgactcagtc
      121 tccctctgtg tctgggtctc ctggacagtc ggtcaccatt tcctgcactg gaaccagcag
      181 tgacattggt ggttataacc gtgtctcctg gtaccaacag cacccaggca aagcccccaa
      241 actcatgatt tatgacgtca gtgatcggcc ctcaggggtc tctgatcgct tctctggttc
      301 caagtctggc aacacggcct ccctgatcat ctctgggctc caggctgagg acgaggctga
      361 ttattactgc agctcataca caagcactac cacttggcta ttcggcggag ggacccgcct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000246             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:10949:4444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000246
VERSION     KCVO01000246.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10949:4444"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..422
                     /note="immunoglobulin light chain variable region"
     V_region        104..422
     V_segment       104..385
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72275.1"
                     /translation="DFYCQSTDSSGYIF"
     J_segment       386..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT          101 a          135 c          119 g          105 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgtg gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actgacaaaa aattatgctc agtggttcca gcagaagcca ggccaggccc ctgtgctgct
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gttccagttc
      301 agggacaaca gttaccttga ccatcagtcg ggcccaggta gaagatgagg ctgactttta
      361 ttgtcaatca acagacagca gtggttacat cttcggtgct gggacccggc tcaccgtcct
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01000247             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:27170:8459
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000247
VERSION     KCVO01000247.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:27170:8459"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..451
                     /note="immunoglobulin light chain variable region"
     V_region        130..451
     V_segment       130..417
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72276.1"
                     /translation="DYYCSSTDFSGNHVF"
     J_segment       418..451
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        452..>489
                     /gene="IGLC"
BASE COUNT          100 a          152 c          132 g          105 t
ORIGIN      
        1 acatggggaa gagaagccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactccccc tcctcacttt ctgcacaggc
      121 tctgcagcct cctatgagct gacacagcca ccctcggtgt cagtgtcccc aggacagacg
      181 gccaggatca cctgctctgg agatgcattg ccagaaaaat atgcttattg gttccaacag
      241 aagccaggcc agtcccctgt gctgatcatc aatgaggaca ccaaacggcc ctctgggatc
      301 cctgagagat tctctggctc cagctcaggg acagtggcca ccttgactct cagtggggcc
      361 caggtggagg atgaagctga ctactactgt tcctcaacag atttcagtgg taatcatgta
      421 ttcggcggag ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact
      481 ctcttcccg
//
LOCUS       KCVO01000248             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:12917:14142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000248
VERSION     KCVO01000248.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12917:14142"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72277.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          142 c          137 g           98 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgag ctcactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggaggcaatg
      181 ttggaagtga atatgtccac tggtatcaac agaagccacc gcaggcccct gtggtggtca
      241 tctattataa tactgaccgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtttg ggacagtagg agtgatcata gtttattggg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000249             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:24504:19712
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000249
VERSION     KCVO01000249.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:24504:19712"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72278.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       390..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           92 a          142 c          126 g          101 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccagaaaa atatgcttat tggttccagc agaagccagg ccagtcccct gtgctgatca
      241 tcaatgagga cagcaaacgg ccctctggga tccctggaag attctctggc tccagctcag
      301 ggacagtggc caccttgact ctcagtgggg cccaggtgga ggatgaagct gactactact
      361 gttcctcaac agatagtagt ggtaattatg tattcggcgg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000250             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:20941:14209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000250
VERSION     KCVO01000250.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20941:14209"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72279.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       393..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           94 a          145 c          126 g          102 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccctcctc actttctgca caggctctgc agcctcctct gagctgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg
      181 cattgtcaaa atactatgct tattggttcc agcagaagcc aggccagtcc cctgtggcga
      241 tcatctatga ggacaacaaa cggccctctg ggatccctga gagaatctct ggctccagct
      301 cagggacagt ggccaccttg actatcagtg gggcccaggt cgaggatgaa gctgactact
      361 actgttactc aacagatagc agtggtacta atggcttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000251             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:18803:3252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000251
VERSION     KCVO01000251.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18803:3252"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72280.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       394..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          140 c          139 g           96 t
ORIGIN      
        1 acatgggggt ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag actctgcggt ctcctatgac ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaatg
      181 ttggaagtga atatgtgcac tggtaccaac agaaaccagc gcaggcccct gtggtggtca
      241 tccattataa tagtgaccgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatcatt gtgtattggg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000252             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:17244:7354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000252
VERSION     KCVO01000252.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:17244:7354"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..382
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72281.1"
                     /translation="DYWCQSTDSSGFIF"
     J_segment       385..419
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT           99 a          133 c          123 g          102 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacaacc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaat tatggtcagt ggttccagca gaagccgggc caggcccctg tgttgctgat
      241 atataaagac agtgagaggc cctcagggat ccctgggcga ttctctagct ccagttcagg
      301 gacatcaatt accttgacca tcagtggggc ccaggcagag gatgaggctg actattggtg
      361 tcaatcaaca gacagcagtg gtttcatctt cggtgctggg acccgactca ccgtcctagg
      421 tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01000253             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:10018:13176
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000253
VERSION     KCVO01000253.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10018:13176"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72282.1"
                     /translation="DYYCYSTDSSGNGLF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           93 a          140 c          115 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattccca gaaaaatttg
      181 cttattggta ccagcagaaa ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagaca
      361 gcagtggtaa tggcttattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000254             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:19610:12385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000254
VERSION     KCVO01000254.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19610:12385"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..446
                     /note="immunoglobulin light chain variable region"
     V_region        101..446
     V_segment       101..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72283.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       410..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           88 a          162 c          125 g          109 t
ORIGIN      
        1 acatggggct gggtctgtgg cctcagaggt agccgtgtcc accatggccc tgactcctct
       61 cctcctcctg ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgactcagcc
      121 accctccctg tctgcatccc cgggagcatc ggccagactc ccctgcaccc tgagcagtga
      181 cctcagtgtt ggtagtaaaa acatgtactg gtaccagcag aagccaggga gcgctcccag
      241 gttattcctg tactactact ccgactcaga caagcagctg ggacctgggg tccccaatcg
      301 agtctctggc tccaaggaga cctcaagtaa cacagcgttt ttgctcatct ctgggctcca
      361 gcctgaggac gaggccgatt attactgtca ggtgtatgac agtactggag tgttgttcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCVO01000255             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:8682:9000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000255
VERSION     KCVO01000255.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8682:9000"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72284.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       397..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          142 c          141 g           97 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acaggctctg cggtctccta tgagctcact
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg tgggggaggc
      181 aatgttggaa gtgaatatgt ccactggtat caacagaagc caccgcaggc ccctgtggtg
      241 gtcatctatt ataatagtga ccggccctca gggatccctg agcgattctc tggctccaaa
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag taggagtgat catagtttat tgggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000256             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:12520:6865
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000256
VERSION     KCVO01000256.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12520:6865"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72285.1"
                     /translation="DFYCYSRDSSENQSVF"
     J_segment       379..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           95 a          137 c          115 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca agaaaatatg
      181 tatattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaggacaaca
      241 aacggccctc tgggattcct gagagattct ctggctccac ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aaggtgactt ctactgttac tcaagagata
      361 gtagtgaaaa tcaaagcgtc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000257             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:21999:15358
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000257
VERSION     KCVO01000257.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21999:15358"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..306
                     /note="immunoglobulin light chain variable region"
     V_region        87..306
     V_segment       87..266
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <228..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72286.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       270..306
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           66 a          106 c           97 g           75 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacaga aggcaggcca gtcccctgtg ctgatcatct
      121 atgaggacag caaacggccc tctgggatcc ctgagagatt ctctggctcc agttcaggga
      181 cagtggccac cttgactatc ggtggggccc aggtggagga tgaagctgac tactactgtt
      241 actcaacaga taacagcgat actcataggg gcttcttcgg aggagggacc cggctgaccg
      301 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000258             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:21426:16697
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000258
VERSION     KCVO01000258.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21426:16697"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..406
                     /note="immunoglobulin light chain variable region"
     V_region        87..406
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72287.1"
                     /translation="DYYCYSTDTSAFHVF"
     J_segment       375..406
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>446
                     /gene="IGLC"
BASE COUNT           88 a          140 c          116 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagta
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggtcacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagata
      361 ccagtgcttt tcatgtattc ggcggaggga cccggctgac cgtcctgggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000259             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:16623:6305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000259
VERSION     KCVO01000259.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16623:6305"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..392
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72288.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       394..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          152 c          124 g          103 t
ORIGIN      
        1 acatgggggc acaggaggca gcactcagga cagtctccag catggcctgg tctcctctcc
       61 tcctcaccct tctcattcac tgcacagggt cctgggccca gtctgtgctg acgcagccgc
      121 cctcagtgtc tggggacccc gggcagaggg tcaccatctc gtgcactggg agcagctcca
      181 acattggagg ttattttgta tactggtacc agcagttccc aggaacagcc cccaaactcc
      241 tcatctatga caattataag cgaccctcag ggatttctga ccgattctct ggctccaagt
      301 ctggtacctc agcctccctg accatcactg ggctccagcc tggggatgag gctgattatt
      361 actgcggagc atgggatagc agcctgagtg ctcgcttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000260             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:5576:17360
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000260
VERSION     KCVO01000260.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5576:17360"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72289.1"
                     /translation="DYYCVIWHNNVWVF"
     J_segment       403..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           89 a          154 c          121 g          112 t
ORIGIN      
        1 acatggggac tgcggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaccctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgcgcagt ggcatcagtg
      181 ttggtagtta cagggtattc tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgaacttcca cacagactca gataagcacc agggatctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctgggctc cagtctgagg
      361 atgaggccga ctattactgt gtgatttggc acaacaatgt ttgggtattc ggcggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000261             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:21014:11455
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000261
VERSION     KCVO01000261.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:21014:11455"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72290.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       412..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          158 c          130 g          107 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggaccccgg gcagagggtc accatctcgt
      181 gcactgggag cagctccaac attggaagtt atcttgtata ctggtaccag cagttcccag
      241 ggacagcccc caaactcctc atctatgaca ataataagcg accctcaggg atttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagcctg
      361 gggatgaggc tgattattac tgcggagcat gggatagcag cctgagtgct cgcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01000262             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:10401:12244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000262
VERSION     KCVO01000262.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:10401:12244"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..430
                     /note="immunoglobulin light chain variable region"
     V_region        107..430
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72291.1"
                     /translation="DYFCCSYADTYTFVF"
     J_segment       407..430
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>475
                     /gene="IGLC"
BASE COUNT           83 a          157 c          122 g          113 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactttgt ctcctggtac caacaacatc caggcacagc
      241 ccccaaactc atgatttatg aggtcaatca gcggccctca ggggtctctg atcgcttctc
      301 tggctcaaag tctggcaaca cggcctccct gaccgtctcc ggggtccagg ctgaggacga
      361 ggctgattat ttctgctgct catatgcaga cacctacact tttgttttcg gaagtggcac
      421 caggttgacc gtcgtcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01000263             507 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:14809:12460
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000263
VERSION     KCVO01000263.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 507)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 507)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..507
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14809:12460"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    142..469
                     /note="immunoglobulin light chain variable region"
     V_region        142..469
     V_segment       142..429
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <391..>441
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72292.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       433..469
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        470..>507
                     /gene="IGLC"
BASE COUNT          106 a          153 c          139 g          109 t
ORIGIN      
        1 acatggggct gggaaggaat aagagaagcc tagggagccc agctgtgctg tgggctcagg
       61 aggcagagct ctgggtgtct caccatggcc tggattcctc tcctactccc cctcctcact
      121 ttctgcacag gctctgcagc ctcctatgag ctgacacagc caccctcggt gtcagtgtcc
      181 ccaggacaga cggccaggat cacctgctct ggagatgcat tgccaaaaaa atttgcttct
      241 tggttccagc agaagccagg ccagtcccct gtgctaatca tctatgacga cagcaaacgg
      301 ccctctggga tccctgagag attctctggc tccagctcag ggacagtggc caccttgact
      361 atcattgggg cccaggtgga ggatgaagct gactaccact gtttctcaac agatagcagt
      421 ggtaatcata ggggcttatt cggaggaggg acccggctga ccgtcctagg tcagcccaag
      481 gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000264             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:12576:13997
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000264
VERSION     KCVO01000264.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12576:13997"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72293.1"
                     /translation="DYYCYSMDSSTYLGFF"
     J_segment       388..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          144 c          122 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tacgcttatt ggttccagca gaagccaggc cagtcccctg tattgatcat
      241 ctatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaatg gatagcagta cttatcttgg cttcttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000265             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:17388:10650
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000265
VERSION     KCVO01000265.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:17388:10650"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72294.1"
                     /translation="DYYCQVWDSIPDHSIF"
     J_segment       395..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          150 c          133 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagtctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggggaca
      181 acattggaac tgaatatgtg cactggtacc agcagaagcc accgcaggcc cctgtggtgg
      241 tcatctatta taatactgac cggccctcag ggatccctga gcgattctca ggctccaaat
      301 cagggaacac cggcaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt attcctgatc attccatctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01000266             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:7794:15214
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000266
VERSION     KCVO01000266.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7794:15214"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..432
                     /note="immunoglobulin light chain variable region"
     V_region        105..432
     V_segment       105..392
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72295.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       396..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           95 a          143 c          126 g          106 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccctcctc actttctgca caggctctgc agcctcctat gagctgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatctcctgc tctggagatg
      181 cattgccaaa aaaatttgct tcttggttcc agcagaaggc aggccagtcc cctgtgttga
      241 tcatctatga ggacaacaaa cggccctctg ggatccctga gagattctct ggctccagtt
      301 cagggacagt ggccaccttg actatcagtg gggcccaggt ggaagatgaa gctgactact
      361 actgttactc aacagataac agtgatactc ataggggctt cttcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000267             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:14658:4010
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000267
VERSION     KCVO01000267.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:14658:4010"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    81..411
                     /note="immunoglobulin light chain variable region"
     V_region        81..411
     V_segment       81..374
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72296.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       375..411
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           83 a          147 c          117 g          102 t
ORIGIN      
        1 acatggggag gacaatctcc agcatggcct ggttccctct cctcctcacc ctcctcactc
       61 actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc tccctcagcg tctgaggccg
      121 ccgggaagag tgtcaccatc tcctgttctg gaagcacctc caacatcgga agtaacagtg
      181 tgtcctggta cctgcagctc ccagaaacgg ctcccaaact cctcatctat tataatgatc
      241 ggcgagcctc aggtgtctct gaccgattct ctggctccaa gtctggcccg tcagcctccc
      301 tggccatcag tgggctcgag accgaagatg aggctgatta ttactgcgca gtatgggatg
      361 atagcctgag cggtgtgtta ttcggaggag ggacccgact gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000268             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:8876:20544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000268
VERSION     KCVO01000268.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8876:20544"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..416
                     /note="immunoglobulin light chain variable region"
     V_region        95..416
     V_segment       95..376
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72297.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       380..416
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           98 a          144 c          116 g           96 t
ORIGIN      
        1 acatgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc ctctcctact
       61 ccccatcctc actttctgca caggctctgc agcctcctat gagctgacac agccaccctc
      121 gttgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg cattgccaga
      181 aaaatatgct tattggtacc agcagaaacc aggccagtcc cctatgctga tcatctatga
      241 ggacaacaaa cggccctctg ggatccctga aagattctct ggctccagct cagggacagt
      301 ggccaccttg actatcactg gggcccaggt ggaggatgaa gctgactact actgttactc
      361 agcagacaac agtggtcagg gctcattcgg aggagggacc cggctgaccg tcctaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000269             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:20240:8971
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000269
VERSION     KCVO01000269.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20240:8971"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..454
                     /note="immunoglobulin light chain variable region"
     V_region        130..454
     V_segment       130..417
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72298.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       422..454
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT          101 a          149 c          134 g          108 t
ORIGIN      
        1 acatggggaa gagaagccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactccccc tcctcacttt ctgcacaggc
      121 tctgcagcct cctatgagct gacacagcca ccctcggtgt cagtgtcccc aggacagacg
      181 gccaggatca cctgctctgg agatgcattg ccaaaaaagt atgcttattg gttccagcag
      241 aagccaggcc agtcccctgt gctgatcatc tatgaagacg acaaacggcc ctctgggatc
      301 cctgagagat tctctggctc cagctcaggg acagtggcca ccttgactat cagtggggcc
      361 caggtggagg atgaagctga ctactactgt tactcaatag atagtagtgg tagtcatagc
      421 gtcttcggtg ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc
      481 actctgttcc cg
//
LOCUS       KCVO01000270             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:10787:17970
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000270
VERSION     KCVO01000270.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10787:17970"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72299.1"
                     /translation="DYYCYSADSSGNGLF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           91 a          139 c          119 g           97 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca caaaaatatg
      181 cttattggtg ccagcagaaa ccaggccagt cccctgtggt gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccgcct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 gcagtggtaa tggcttattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000271             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:15728:16722
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000271
VERSION     KCVO01000271.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15728:16722"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..383
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72300.1"
                     /translation="DYYCQVWDSYSDHWVF"
     J_segment       389..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           81 a          145 c          141 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactgcacag gctctgcggt ctcctatgag ttgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggcccggat cacctgtggg ggagacaaca
      181 ttggaagtaa aagtgtgcag tggttccagc agaagccacc gcaggctcct gtgctggtca
      241 tttatgctga tagcgaacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaatgccgc caccctgacc atcagcgggg tcgcggccgg gaatgaggct gactattact
      361 gtcaggtgtg ggacagttat agtgatcatt gggtcttcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000272             506 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:10503:2854
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000272
VERSION     KCVO01000272.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 506)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 506)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..506
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:10503:2854"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    138..468
                     /note="immunoglobulin light chain variable region"
     V_region        138..468
     V_segment       138..431
                     /gene="IGLV8-111"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <396..>440
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72301.1"
                     /translation="DYYCSLYMGSGVDVF"
     J_segment       432..468
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        469..>506
                     /gene="IGLC"
BASE COUNT          104 a          156 c          127 g          119 t
ORIGIN      
        1 acatggggga aaaggccctg aggaaaacaa actccagctg agaagcctga gagcacttgg
       61 ccttcataag tgtccccacc atggcctgga tgatgcttct cctcggactc cttgcttatg
      121 gctcaggagt ggattctgag actgtggtga cccaggagcc atcgttgtct gtgtcccctg
      181 gaggaacaat cacactcacc tgtggcctga actctggctc agtctctacc agtcattacc
      241 ccagctggta ccagcagacc ccaggccagg ctccacgcat actcatctac agcacaaaca
      301 ttcgcccttc tggggtccct gatcgattct ctggctccat ccttgggaac aaagctgccc
      361 tcaccctcac gggggctcag gcagacgatg aatctgatta ttactgttcg ctctacatgg
      421 gtagtggcgt tgatgtgttc ggcagtggca ccaagttgac cgtcctcggt cagcccaagg
      481 cttccccctt ggtcactctg ttcccg
//
LOCUS       KCVO01000273             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:6297:7519
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000273
VERSION     KCVO01000273.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:6297:7519"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..448
                     /note="immunoglobulin light chain variable region"
     V_region        117..448
     V_segment       117..408
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <372..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72302.1"
                     /translation="DYYCQSSDTSLNDHVLF"
     J_segment       413..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>488
                     /gene="IGLC"
BASE COUNT           97 a          162 c          119 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcat ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctcgtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac acagccgccc tcagtgtctg gggccccagg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaggtt attatgtata ctggtaccag caactcccag
      241 gaatggcccc caaactcctc atctatgaca ataataagcg accctcaggg atttctgacc
      301 gagtctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagactg
      361 aggatgaggc tgattattac tgccaatcct ctgacaccag cctaaatgat catgtgttat
      421 tcggaggagg gacccggctg accgtcctcg gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCVO01000274             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:24120:5210
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000274
VERSION     KCVO01000274.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:24120:5210"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..422
                     /note="immunoglobulin light chain variable region"
     V_region        104..422
     V_segment       104..385
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72303.1"
                     /translation="DYYCQSTDSSGYIF"
     J_segment       386..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT          102 a          135 c          119 g          104 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgtg gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actgacaaaa aattatgctc agtggttcca gcagaagcca ggccaggccc ctgtgctgct
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gttccagttc
      301 agggacaaca gttaccttga ccatcagtcg ggcccaggta gaagatgagg ctgactatta
      361 ttgtcaatca acagacagca gtggttacat cttcggtgct gggacccggc tcaccgtcct
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01000275             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:12685:3994
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000275
VERSION     KCVO01000275.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:12685:3994"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72304.1"
                     /translation="DYYCHSLDTSGNDVF"
     J_segment       392..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           91 a          143 c          124 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttact ggttccagca gaagccaggc cagtcccctg tggcgatcat
      241 ctatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 tcattcatta gataccagtg gtaatgatgt tttcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000276             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:8864:15980
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000276
VERSION     KCVO01000276.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:8864:15980"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..381
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72305.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       384..421
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           86 a          139 c          139 g           95 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctgcacagac tctgtggtct cctatgaatt gactcagcca
      121 cgctcagtgt ccgtgtcccc aggacagacg gccaggatca cctgtggggg agacagcatt
      181 ggaagtagaa gtgtgcagtg gtaccagcag aagccaccgc aggcccttgt actggtcatc
      241 tatgctgata gcgaacggcc ctcagggatc cctgagcgat tctctggctc caatttaggg
      301 aacaccgcca ccctgaccat cagcggcgtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtagtag tgatgtgtta ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000277             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:9678:2376
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000277
VERSION     KCVO01000277.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9678:2376"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72306.1"
                     /translation="DYHCQVWDSSSDVLF"
     J_segment       386..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           84 a          143 c          139 g           95 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactgcacag actctgtggt ctcctttgaa ttgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacagta
      181 ttggaagtag aagcgtgcag tggtaccagc agaagccacc gcaggccctt gcactggtca
      241 tctatgctga tagcgaacgg ccctcaggga tccctgagcg cttctctggc tccaatctag
      301 ggaacaccgc caccctgacc attagcggcg tcgaggccgg ggatgaggct gactatcact
      361 gtcaggtgtg ggacagtagt agtgatgtgt tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000278             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:14796:15852
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000278
VERSION     KCVO01000278.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14796:15852"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72307.1"
                     /translation="DYYCAAWDDSLSSPLF"
     J_segment       410..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          155 c          122 g          113 t
ORIGIN      
        1 acatggggca ccttcagctg cgggtacaga aggcaggact caggataatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gccaccctca acgtctgggg ctcccgggca gagtgtcacc atctcttgct
      181 ctggaagcag tttcaacatt ggaagtaatt atgtaaactg gtaccagcag ctcccaggaa
      241 cggcccccaa actcctcatc tattttagta atcagcggcc ctcaggggtc cctgaccgat
      301 tctctggctc taagtctggc acctcagcct ccctggccat cactggtctc cgatctgagg
      361 atgaggctga ttattactgt gcagcatggg atgatagtct gagcagtccc ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000279             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:27466:18606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000279
VERSION     KCVO01000279.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:27466:18606"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72308.1"
                     /translation="DYHCMIRHNNAYIF"
     J_segment       403..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          155 c          113 g          114 t
ORIGIN      
        1 acatggggac tgcggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggaaca tcagccagac tcacctgcac cttgcgcagt ggcatcagtg
      181 ttggtagtta cgggattttc tggtaccaac agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gataagtacc agggatctgg agtccccagc cgcttctctg
      301 gatccaagga tacttcggcc aatgcaggct ttttactcat ctctgggctc cagtctgagg
      361 atgaggctga ctatcactgt atgattcggc acaacaatgc ttacatcttc ggtggtggga
      421 cccggctcac cgtcctaggt cagccaaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCVO01000280             330 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:16375:7247
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000280
VERSION     KCVO01000280.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 330)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 330)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..330
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:16375:7247"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    73..292
                     /note="immunoglobulin light chain variable region"
     V_region        73..292
     V_segment       73..254
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <217..>264
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72309.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       258..292
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        293..>330
                     /gene="IGLC"
BASE COUNT           62 a          105 c           89 g           74 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacagcagaa gccaggccag tcccctgtgc tgatcatcta tgaggacagc
      121 agacggccct ctgggatccc tgagagattc tctggctcca gctcagggac agtggccacc
      181 ttgactatca gtggggccca gggggaggat gaagctgact actactgtta ttcaatggat
      241 agcagtggta ctcagagcat cttcggtgct gggacccggc tcaccgtcct aggtcagccc
      301 aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01000281             494 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:13644:9380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000281
VERSION     KCVO01000281.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 494)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13644:9380"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..456
                     /note="immunoglobulin light chain variable region"
     V_region        123..456
     V_segment       123..416
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72310.1"
                     /translation="DYYCLSYDSSLSAHYIF"
     J_segment       419..456
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>494
                     /gene="IGLC"
BASE COUNT           96 a          166 c          122 g          110 t
ORIGIN      
        1 acatgggggg ggaagctctg cttcagctgt gggcacagga ggcagcactc aggacagtct
       61 ccagcatggc ctcgtctcct ctcctcctca cccttctcat tcactgcaca gggtcctggg
      121 cccagtctgt gctgacacag ccaccctcag tgtctggggc cccagggcag agggtcacca
      181 tctcgtgcac tgggagcagc tccagcattg gaggtgatta tgtttcctgg taccaacagc
      241 tcccaggaac gacccccaaa ctcctcatct atcaaaataa taagcgaccc tcaggggttt
      301 ctgaccgatt ctctggctcc aagtctggta cctcagcctc cctgaccatc actggactcc
      361 agactgagga tgaggctgat tactactgcc tgtcctatga cagcagcctg agtgctcatt
      421 acatcttcgg tcctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg
      481 tcactctgtt cccg
//
LOCUS       KCVO01000282             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:17688:9678
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000282
VERSION     KCVO01000282.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17688:9678"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..392
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72311.1"
                     /translation="DYYCLLYSSGVHLF"
     J_segment       394..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           96 a          155 c          113 g          101 t
ORIGIN      
        1 acatgggggg agccagagat cccttccaat accagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtggctc cagcactgga
      181 gcagtcacca gtagtaactt tccaaactgg ttccagcaga aacctggaca agtccccagg
      241 ggactcattt acaatacaca caacaaacac tcctggaccc ctgcccggtt ctcaggctcc
      301 ctcgctgggg ccaaagctgc cctgacactg tcaggtgcac agcccgagga cgaggctgac
      361 tattactgct tgctgtattc tagtggtgtt catttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000283             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:19044:10049
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000283
VERSION     KCVO01000283.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19044:10049"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72312.1"
                     /translation="DYYCSTWDNSLSAGLF"
     J_segment       410..446
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           95 a          156 c          126 g          107 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctctccttc tcactctgct ggttcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagcatctgg ggcccccggg cagagggtca ccatctcgtg
      181 cactgggagc agctccaaca ttggaggtta ttctgtatcc tggtaccagc aactcccagg
      241 aacggtcccc aaactcctca tctatgagaa taataagcga ccctcagggg tttctgaccg
      301 attctctggc tccaagtctg gaacctcagc ctccctaacc atcactggac tccagtctca
      361 cgatgaggct gattattact gctcaacatg ggataacagc ctgagtgctg gcttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCVO01000284             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:27579:15017
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000284
VERSION     KCVO01000284.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:27579:15017"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..451
                     /note="immunoglobulin light chain variable region"
     V_region        130..451
     V_segment       130..416
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72313.1"
                     /translation="DYYCYSTDSSGNHIF"
     J_segment       417..451
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        452..>489
                     /gene="IGLC"
BASE COUNT          103 a          152 c          128 g          106 t
ORIGIN      
        1 acatggggaa gagaagccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactccccc tcctcacttt ctgcacaggc
      121 tctgcagcct cctatgagct gacacagcca ccctcggtgt cagtgtcccc aggacagacg
      181 gccaggatca cctgctctgg agatgcattg ccaaaaaaat atgcttattg gttccagcag
      241 aagccaggcc agtcccctgt gctgatcatc tatgacgaca gtaaacggcc ctctgggatc
      301 cctgagagat tctctggctc cagctcaggg acagtggcca ccttgactat cagtggggcc
      361 caggtggagg atgaagctga ctactactgt tactcaacag atagcagtgg taatcacatc
      421 ttcgctactg ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact
      481 ctgttcccg
//
LOCUS       KCVO01000285             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:10668:11754
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000285
VERSION     KCVO01000285.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10668:11754"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..448
                     /note="immunoglobulin light chain variable region"
     V_region        124..448
     V_segment       124..411
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72314.1"
                     /translation="DYYCQVWDSGHDHVFF"
     J_segment       418..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           93 a          150 c          144 g           99 t
ORIGIN      
        1 acatgggtca acgcagagta catggggagc ctggcctcgg gaagcagcct tggcggtgcc
       61 tcagccatgg ccgggaccct tctcctcctc ggcctccttg cttactgcac aggctctgcg
      121 gtctcctatg agctgactca gccaccctcg gtgtcagtgt ccccaggaca gacggccagg
      181 atcacctgtg ggggagacaa ccttggagat aaatatgtac actggtacca gcagaagcca
      241 gcgcaggccc ctgtgctggt catctactat gatagtgacc ggccctcacg gatcactgag
      301 cgattctctg ggtccaaatc agggaacacc gccaccctga ccatcagcgg ggtcgaggcc
      361 ggggatgagg ctgactatta ctgtcaggtg tgggacagtg gtcatgatca tgtctttttc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01000286             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:22588:17765
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000286
VERSION     KCVO01000286.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:22588:17765"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..324
                     /note="immunoglobulin light chain variable region"
     V_region        124..324
     V_segment       124..287
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <249..>296
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72315.1"
                     /translation="DYYCQVWDSSTDHTLL"
     J_segment       291..324
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        325..>362
                     /gene="IGLC"
BASE COUNT           62 a          117 c          104 g           79 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgag ctgactcagc
      121 caccccctgt ggtggtcatc cattataata gtgaccggcc ctcagggatc cctgagcgat
      181 tctctggctc caaatcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggg
      241 atgaggctga ctattactgt caggtgtggg acagtagtac tgatcatact ttattgggag
      301 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      361 cg
//
LOCUS       KCVO01000287             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:18765:5428
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000287
VERSION     KCVO01000287.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:18765:5428"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..432
                     /note="immunoglobulin light chain variable region"
     V_region        105..432
     V_segment       105..397
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72316.1"
                     /translation="DYYCFVYYSGTQFF"
     J_segment       402..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           99 a          155 c          115 g          101 t
ORIGIN      
        1 acatggggtc tctggagcca gagatccctt ccaataccag caccatggcc tggactctgc
       61 tcctcctcca gttcctcctc acttgctgcc cagggtccaa ttctcaggct gtagtgactc
      121 aggagccctc aatgactgtg tccccaggag ggacagtcac tctcacctgt ggctccagca
      181 ctggagcagt caccagtggt aactttccaa actggttcca gcagaaacct ggacaagtcc
      241 ccaggggact gatttacaat acaaacaaca aacactcctg gacccctgcc cggttctcag
      301 gctccctcgc tgggggcaaa gctgccctga cactgtcagg agcacagccc gaggacgagg
      361 ctgattatta ctgcttcgtg tactatagtg gtactcaatt cttcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000288             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:11522:12638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000288
VERSION     KCVO01000288.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11522:12638"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72317.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       390..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           90 a          143 c          127 g          101 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccagaaaa atatgcttat tggttccagc agaagccagg ccagtcccct gtgctgatca
      241 tcaatgagga cagcaaacgg ccctctggga tccctgggag attctctggc tccagctcag
      301 ggacagtggc caccttgact ctcagtgggg cccaggtgga ggatgaagct gactactact
      361 gttcctcaac agatagtagt ggtaattatg tattcggcgg cgggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000289             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:9359:4853
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000289
VERSION     KCVO01000289.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9359:4853"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72318.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           91 a          138 c          117 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagcaaccc tcggtgtcag
      121 tgtctccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctattgttcc tcaacagata
      361 gcagtggtaa tcatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000290             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:21715:4240
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000290
VERSION     KCVO01000290.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:21715:4240"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72319.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       375..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           92 a          143 c          115 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct ctgacctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaatactatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtggc gatcatctat gaggacaaca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtagaggatg aagctgacta ctactgttac tcaacagata
      361 gcagtggtac taatggctta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000291             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:22650:16799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000291
VERSION     KCVO01000291.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:22650:16799"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72320.1"
                     /translation="DYYCGAWDSSLNTRLF"
     J_segment       412..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           92 a          158 c          127 g          108 t
ORIGIN      
        1 acatggggtc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggaccccgg gcagagggtc accatctcgt
      181 gcactgggag cagctccaac attggaggtt atcttgtata ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctatgaca ataataagcg accctcaggg atttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagcctg
      361 gggatgaggc tgattattac tgcggagcat gggatagcag cctgaatact cgcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01000292             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:20659:4305
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000292
VERSION     KCVO01000292.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20659:4305"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72321.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           88 a          161 c          125 g          109 t
ORIGIN      
        1 acatggggtg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtactggagt gttgttcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01000293             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:14080:10776
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000293
VERSION     KCVO01000293.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14080:10776"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72322.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       396..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          144 c          133 g           99 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgag ctgactcagc
      121 caccctcggt gtcagtgtct ccaggacaga cggccaggat cacctgtggg ggagacaacc
      181 ttggagataa atatttacac tggtaccacc agaagccagc gcaggcccct gtgctggtca
      241 tctactatga tagtgaccgg ccctcatgga tccctgagcg attctctggg tccaagtcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtaat aatgatcata tctttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000294             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:15350:10452
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000294
VERSION     KCVO01000294.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:15350:10452"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..400
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72323.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       401..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           83 a          162 c          120 g          109 t
ORIGIN      
        1 acatgggggt gggatctcag gaggcagcac tctcaggacg tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagtctccct ctgtgtctgg gtctcctgga cagtcggtca ccctttcctg cactggaacc
      181 agcagtgaca ttggtggtta taaccgtgtc tcctggtacc aacaccaccc aggcaaagcc
      241 cccaaactca tgatttatga cgtcagtgat cggccctcag gggtctctga tcgcttctct
      301 ggttccaagt ctggcaacac ggcctccctg atcatctctg ggctccaggc tgaggacgag
      361 gctgattatt actgcagctc atacgcaagc acttccactt ggctattcgg cggagggacc
      421 cgcctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000295             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:8964:9210
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000295
VERSION     KCVO01000295.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:8964:9210"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72324.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          161 c          126 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaacg cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000296             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:21997:10986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000296
VERSION     KCVO01000296.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21997:10986"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72325.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       402..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           86 a          156 c          123 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gctcatctct gggctccaga ctgaggacga
      361 ggctgattat tactgcagct catacacaag cagtagtact tgggtattcg gcggagggac
      421 ccggctgacc gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000297             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:12609:8623
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000297
VERSION     KCVO01000297.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12609:8623"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72326.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           91 a          140 c          116 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtact gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gggagattct ctggatccac ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gtagtggtaa ttatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000298             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:13799:12145
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000298
VERSION     KCVO01000298.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13799:12145"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..378
                     /note="immunoglobulin light chain variable region"
     V_region        88..378
     V_segment       88..338
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <306..>350
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72327.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       342..378
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        379..>416
                     /gene="IGLC"
BASE COUNT           88 a          127 c          114 g           87 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc catcctcact ttctgcacag tgtccccagg acagacggcc aggatcacct
      121 gctctggaga tgcattgcca gaaaaatatg cttattggta ccagcagaaa ccaggccagt
      181 cccctatgct gatcatctgt gaggacagca aacggccctc tgggatccct gaaagattct
      241 ctggctccag ctcagggaca gtggccacct tgactatcac tggggcccag gtggaggatg
      301 aagctgacta ctactgttac tcagcagaca acagtggtca gggctcattc ggaggaggga
      361 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000299             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:16145:10661
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000299
VERSION     KCVO01000299.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16145:10661"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..451
                     /note="immunoglobulin light chain variable region"
     V_region        103..451
     V_segment       103..414
                     /gene="IGLV9-51"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72328.1"
                     /translation="DYHCGADHGTGSSFVYVF"
     J_segment       416..451
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        452..>489
                     /gene="IGLC"
BASE COUNT           94 a          152 c          142 g          101 t
ORIGIN      
        1 acatggggga gagactgaag aacccagcat tgcagcatct ccgccatggc ctgggctcct
       61 ctgctcctca ccctcctcag tctcctcaca gggtccctct cccagcctgt gctgactcag
      121 ccatcctctg catcggcctc cctgggagcc tcggtcacac tcacctgcac cctgagtagc
      181 ggctacagta attatgcggt ggactggcac cagcagagac cagggaaggg ccctcagttt
      241 gtgatgcgag tgggcacagg tgggattgtg ggatccaagg gggatggcat ccctgatcgc
      301 ttctcaggct cgggctccgg cctgaatcgg tacctgacca tcaagaacat tcaggaagag
      361 gatgagagtg actaccactg tggggcagac cacggcactg ggagcagctt cgtgtatgtg
      421 ttcggaagtg gcaccaagtt gaccgtcctc ggtcagccca aggcttcccc cttggtcact
      481 ctgttcccg
//
LOCUS       KCVO01000300             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:22698:6624
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000300
VERSION     KCVO01000300.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22698:6624"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72329.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          161 c          120 g          108 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtggtt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg acgtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacacaag cactaccact tggctattcg gcggagggac
      421 ccgcctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000301             410 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:23767:9746
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000301
VERSION     KCVO01000301.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 410)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23767:9746"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..372
                     /note="immunoglobulin light chain variable region"
     V_region        122..372
     V_segment       122..335
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <297..>344
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72330.1"
                     /translation="DYYCAAWDDSLSSPLF"
     J_segment       338..372
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        373..>410
                     /gene="IGLC"
BASE COUNT           81 a          133 c          101 g           95 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacattgg aagtaattat gtaaactggt accagcagct cccaggaacg gcccccaaac
      181 tcctcatcta ttttagtaat cagcggccct caggggtccc tgaccgattc tctggctcta
      241 agtctggcac ctcagcctcc ctggccatca ctggtctccg atctgaggat gaggctgatt
      301 attactgtgc agcatgggat gatagtctga gcagtccctt attcggagga gggacccggc
      361 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000302             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:11902:15582
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000302
VERSION     KCVO01000302.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:11902:15582"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..453
                     /note="immunoglobulin light chain variable region"
     V_region        120..453
     V_segment       120..413
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72331.1"
                     /translation="DYYCLSYDSSLSPHYIF"
     J_segment       416..453
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           95 a          169 c          118 g          109 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctc gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacacagcca ccctcagtgt ctggggcccc aggacagagg gtcaccatct
      181 cgtgcactgg gagcagctcc agcattggag gtgattatct atcctggtac cagcagctcc
      241 caggaacgac ccccaaactc ctcatctatc aaaatcataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtacct cagcctccct gaccatcact gggctccaga
      361 ctgaggatga ggctgattac tactgcctgt cctatgacag cagcctgagt cctcattaca
      421 tcttcggtcc tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca
      481 ctctgttccc g
//
LOCUS       KCVO01000303             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:24279:2922
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000303
VERSION     KCVO01000303.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:24279:2922"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72332.1"
                     /translation="DYHCMIRHNNAYIF"
     J_segment       403..438
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          158 c          112 g          113 t
ORIGIN      
        1 acatggggac tgcggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggaaca tcagccagac tcacctgcac cttgcgcagt ggcatcagtg
      181 ttggtagtta cgggattttc tgttaccaac agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gagaagcacc agggatctgg agtccccagc cgcttctctg
      301 gatccaagga tacttcggcc aatgcaggct ttttactcat ctctgggctc cagtctgagg
      361 atgaggctga ctatcactgt atgattcggc acaacaatgc ttacatcttc ggtgctggga
      421 cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCVO01000304             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:17678:13604
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000304
VERSION     KCVO01000304.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:17678:13604"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..443
                     /note="immunoglobulin light chain variable region"
     V_region        114..443
     V_segment       114..407
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72333.1"
                     /translation="DYYCQSYDSSSSAWVF"
     J_segment       408..443
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>482
                     /gene="IGLC"
BASE COUNT           84 a          158 c          129 g          111 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gtgtctgggg cgcccgggca gagggtcacc atcccctgct
      181 ctgggagcag ctccaatatt ggaggtcatt ttgtgcagtg gttccagcag cttcccggaa
      241 cggcccccaa actcctcatc tatgaaaata ataagcgacc ctcaggggtt tctgatcgat
      301 tctctggctc ccagtctggt acctcagcct ccctgaccat ctctggagtc cagtctgagg
      361 atgaggctga ttattactgc cagtcctatg acagcagctc gagtgcttgg gtattcggcg
      421 gagggacccg gctgaccgtc ctaagtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000305             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:6945:10534
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000305
VERSION     KCVO01000305.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:6945:10534"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72334.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       390..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           91 a          142 c          127 g          101 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccagaaaa atatgcttat tggttccagc agaagccagg ccagtcccct gtgctgatca
      241 tcaatgagga cagcaaacgg ccctctggga tccctgggag attctctggc tccagctcag
      301 ggacagtggc caccttgact ctcagtgggg cccaggtgga ggatgaagct gactactact
      361 gttcctcaac agatagtagt ggtaattatg tattcggcgg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000306             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:15266:13238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000306
VERSION     KCVO01000306.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:15266:13238"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72335.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           92 a          140 c          117 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagactccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatctcct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag gcaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ttcagggaca atggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagata
      361 acagtgatac tcataggggc ttcttcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000307             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:21617:12863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000307
VERSION     KCVO01000307.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:21617:12863"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72336.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          160 c          125 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCVO01000308             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:7792:16760
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000308
VERSION     KCVO01000308.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:7792:16760"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..427
                     /note="immunoglobulin light chain variable region"
     V_region        104..427
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72337.1"
                     /translation="DYFCCSYADTYTFVF"
     J_segment       404..427
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>472
                     /gene="IGLC"
BASE COUNT           82 a          157 c          121 g          112 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actttgtctc ctggtaccaa caacatccag gcacagcccc
      241 caaactcatg atttatgagg tcaatcagcg gccctccggg gtctctgatc gcttctctgg
      301 ctcaaagtct ggcaacacgg cctccctgac cgtctccggg gtccaggctg aggacgaggc
      361 tgattatttc tgctgctcat atgcagacac ctacactttt gttttcggaa gtggcaccag
      421 gttgaccgtc gtcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01000309             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:8098:15863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000309
VERSION     KCVO01000309.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8098:15863"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72338.1"
                     /translation="DYYCYSTRSSAYHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          143 c          123 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ctctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtgcag gatgaagctg actactactg
      361 ttactcaact cgtagcagtg cttatcatgg cttattcgga ggagggacct ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000310             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:20448:19068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000310
VERSION     KCVO01000310.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:20448:19068"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72339.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           91 a          141 c          119 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatctcct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag gcaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct gtggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagata
      361 acagtgatac tcataggggc ttcttcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000311             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:11550:18455
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000311
VERSION     KCVO01000311.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:11550:18455"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72340.1"
                     /translation="DYHCYSTDSSTNHGLF"
     J_segment       393..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           96 a          143 c          126 g          102 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccctcctc actttctgca caggctctgc agcctcctat gagctgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg
      181 cattgccaaa aaaatatgct tgttggttcc agcagaagcc agggcagtcc cctgtactga
      241 tcatctatgg agacagcaaa cggccccctg ggatcactga gagattctct ggctccagct
      301 cagggactgt ggccaccttg actatcagtg gggcccaggt ggaggatgaa gctgactacc
      361 attgttactc aacagatagc agtactaatc atggcttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000312             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:14718:15051
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000312
VERSION     KCVO01000312.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14718:15051"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..444
                     /note="immunoglobulin light chain variable region"
     V_region        116..444
     V_segment       116..410
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72341.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       411..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>484
                     /gene="IGLC"
BASE COUNT           88 a          158 c          126 g          112 t
ORIGIN      
        1 acatggggag gtccagtgct gggatctcag gaggcagcac tctcaggacg tctccaccat
       61 ggcctgggct ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc
      121 tgccctgact cagtctccct ctgtgtctgg gtctcctgga cagtcggtca ccatttcctg
      181 cactggaacc agcagtgaca ttggtgatta taaccgtgtc tcctggtacc aacaacaccc
      241 aggcaaagcc cccaaactca tgatttatga ggtcagtgat cggccctcag gggtctctga
      301 tcgcttctct ggttccaagt ctggcaacac ggcctccctg atcatctctg ggctccaggc
      361 tgaggacgag gctgattatt actgcagctc atacacaagc agtagcactt gggttttcgg
      421 cggagggacc cggctgaccg tccttggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCVO01000313             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:15186:17432
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000313
VERSION     KCVO01000313.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:15186:17432"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72342.1"
                     /translation="DYYCYSSDSSADYWVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           91 a          141 c          127 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggtt ccagctcagg
      301 gacagtggcc accttgacta tcaatggggc ccaggtggag gatgaagctg actactactg
      361 ttactcatca gatagcagtg ctgattattg ggtgttcggc ggagggaccc ggctgaccgt
      421 cccaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000314             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:16096:9610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000314
VERSION     KCVO01000314.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16096:9610"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72343.1"
                     /translation="DYYCASWDNSLSSDVF"
     J_segment       391..427
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          148 c          115 g          111 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaat
      181 attggaagta attatgtata ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 atctatctta gtaatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcatcat gggataacag cctgagcagt gatgtgttcg gaagtggcac caagttgacc
      421 gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01000315             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:24660:3594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000315
VERSION     KCVO01000315.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24660:3594"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72344.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           85 a          155 c          123 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagcacttgg gttttcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000316             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:15123:11507
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000316
VERSION     KCVO01000316.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:15123:11507"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..266
                     /note="immunoglobulin light chain variable region"
     V_region        8..266
     V_segment       8..229
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <191..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72345.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       236..266
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        267..>304
                     /gene="IGLC"
BASE COUNT           66 a           87 c           88 g           63 t
ORIGIN      
        1 acatgggggg ggagacaacc ttggagataa atatctacac tggtaccacc agaagccagc
       61 gcaggcccct gtgctggtca tctactatga tagtgaccgg ccctcatgga tccctgagcg
      121 attctctggg tccaagtcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg
      181 ggatgaggct gactattact gtcaggtgtg ggacagtaat aatgatcata tctttttcgg
      241 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      301 cccg
//
LOCUS       KCVO01000317             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:12903:17329
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000317
VERSION     KCVO01000317.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12903:17329"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72346.1"
                     /translation="DYYCQVWDSSNDHILF"
     J_segment       395..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          146 c          136 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaga taaatatgta cactggtacc agcagaagcc agcgcgggcc cctgtgctgg
      241 tcatctacta tgatagtgac cggccctcat ggatccctga gcgattctct gggtccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtaatgatc atatcttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000318             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:17623:17710
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000318
VERSION     KCVO01000318.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17623:17710"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72347.1"
                     /translation="DYYCQVWDSSSDVFF"
     J_segment       396..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          143 c          138 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gtattggaag tacaagtgtg cagtggtacc agcagaagcc accgcaggcc cttgtactgg
      241 tcatctatgc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggcacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tattcttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000319             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:22481:15549
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000319
VERSION     KCVO01000319.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:22481:15549"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72348.1"
                     /translation="DYYCQVWHYISDHPLF"
     J_segment       399..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          140 c          140 g          101 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgc ggcctcctat gagctgactc
      121 agtcgccctc ggtgtcggtg tcccagggac agacggccag gatcacctgt gggggaaaca
      181 gcattcgaag tgaagttgtg cagtggtacc agcagaaggc agcgcaggcc cctgtattgg
      241 tcatctatga tgattttgaa cggccctcag ggatccctga tcgagtctct ggatccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtggcattac attagtgatc acccgttgtt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000320             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:10526:4803
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000320
VERSION     KCVO01000320.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10526:4803"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72349.1"
                     /translation="DYYCAAWDDSLNSPFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          155 c          113 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaac
      181 attggaagta attatgtaaa ctggtaccag caactcccag gaacgacccc caaactcctc
      241 atctatttta ctaatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcggcat gggatgacag cctgaacagt cccttcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000321             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:7510:10211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000321
VERSION     KCVO01000321.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:7510:10211"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72350.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       407..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           90 a          155 c          129 g          106 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggac cccgggcaga gggtcaccat ctcgtgcact
      181 gggagcagct ccaacattgg aggttatttt gtatactggt accagcagtt cccaggaaca
      241 gcccccaaac tcctcatcta tgacaataat aagcgaccct cagggatttc tgaccgattc
      301 tctggctcca agtctggtac ctcagcctcc ctgaccatca ctgggctcca gcctggggat
      361 gaggctgatt attactgcgg agcatgggat agcagcctga gtgctcgctt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000322             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:17032:14963
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000322
VERSION     KCVO01000322.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17032:14963"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72351.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           92 a          145 c          116 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgcccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gacgacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacca
      301 tgactatcat tggggcccag gtggacgatg aagctgacta ccactgtttc tcaacagata
      361 gcagtggtaa tcataggggc ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000323             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:28430:8411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000323
VERSION     KCVO01000323.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:28430:8411"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..254
                     /note="immunoglobulin light chain variable region"
     V_region        8..254
     V_segment       8..214
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72352.1"
                     /translation="DYYCQSYDSSLNTHVLF"
     J_segment       217..254
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>292
                     /gene="IGLC"
BASE COUNT           62 a           90 c           71 g           69 t
ORIGIN      
        1 acatggggga ggttattatg tatactggta ccagcagctc ccaggaatgg cccccaaact
       61 cctcatctat gacaataata accgaccctc aggggtttct gaccgattct ctggctccaa
      121 gtctggtgcc tcagcctccc tgaccatcac tgggctccag actgaggatg aggctgatta
      181 ttactgccag tcctatgaca gcagcctgaa tactcatgtg ttattcggag gagggacccg
      241 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000324             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:6180:16216
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000324
VERSION     KCVO01000324.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:6180:16216"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72353.1"
                     /translation="DYYCGSYRRGSTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           82 a          152 c          133 g          108 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcgggac gtctccacca tggcttgggc
       61 tctggtcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtccgtc accatctcct gcactggaac
      181 caagagtgac attggtggtt ataacggtgt ctcctggtac caacagtatt caggcacagc
      241 ccccagactc ctgatttatg aggtcagtca gcggccctca ggggtctctg ctcgcttctc
      301 tgggtacaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgcggct catataggag gggaagcact tgggtgttcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000325             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:19563:8423
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000325
VERSION     KCVO01000325.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19563:8423"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..395
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72354.1"
                     /translation="DYYCLLYSSGVHLF"
     J_segment       397..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           97 a          154 c          113 g          104 t
ORIGIN      
        1 acatggggtc tggagccaga gatcccttcc aataccagca ccatggcctg gactctgctc
       61 ctcctccagt tcctcctcac ttgctgccca gggtccaatt ctcaggctgt agtgactcag
      121 gagccctcaa tgactgtgtc cccaggaggg acagtcactc tcacctgtgg ctccagcact
      181 ggagcagtca ccagtagtaa ttttccaaac tggttccagc agaaacctgg acaagtcccc
      241 aggggactga tttacaatac acacaacaaa cactcctgga cccctgcccg gttctcaggc
      301 tccctcgctg gggccaaagc tgccctgaca ctatcaggtg cacagcccga ggacgaggct
      361 gactattact gcttgctgta ttctagtggt gttcatttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000326             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:9286:13192
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000326
VERSION     KCVO01000326.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:9286:13192"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72355.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          153 c          124 g          112 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtccgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttttg agcgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcttg atttatgagg tcagttatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct gccaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattat tgcagctcat acacaagtag tagtacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000327             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:14912:15181
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000327
VERSION     KCVO01000327.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14912:15181"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72356.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           94 a          141 c          124 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 caatgaggac agcaaacggc cttctgggat ccctgagaga atctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtagag gatgaagctg actactactg
      361 ttcctcaaca gatagtagtg gtaatcatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000328             382 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:24502:20708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000328
VERSION     KCVO01000328.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 382)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:24502:20708"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..344
                     /note="immunoglobulin light chain variable region"
     V_region        20..344
     V_segment       20..307
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <269..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72357.1"
                     /translation="DYYCQVWDSSTNHILF"
     J_segment       310..344
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>382
                     /gene="IGLC"
BASE COUNT           79 a          114 c          110 g           79 t
ORIGIN      
        1 acatgggggc tctgcggtct cctatgagct gactcagcca ccctcggtgt cagtgtcccc
       61 aggacagacg gccaggatca cctgtggggg agacaacctt gcagatgaat atgtacactg
      121 gtaccagcag aagccagcgc gggccccttt actggtcatc tactatgata gtgaccggcc
      181 ctcatggatc cctgagcgat tctctgggtc caaatcaggg aacaccgcca ccctgaccat
      241 cagcggggtc gaggccgggg atgaggctga ctattactgt caggtgtggg acagtagtac
      301 taatcatatc ttattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc
      361 cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000329             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:4003:13064
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000329
VERSION     KCVO01000329.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:4003:13064"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    73..289
                     /note="immunoglobulin light chain variable region"
     V_region        73..289
     V_segment       73..252
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <214..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72358.1"
                     /translation="DYYCYSTISSGNDRIF"
     J_segment       256..289
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>327
                     /gene="IGLC"
BASE COUNT           64 a          102 c           85 g           76 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacagaagcc aggccagtcc cctgtgctga tcatctatga ggacagcaaa
      121 cggccctctg ggatccctga gagattctct ggctccagct cagggacagt ggccaccttg
      181 actatcagtg gggcccaggt ggaggatgaa gctgactact actgttactc aacaattagt
      241 agtggtaatg ataggatctt cggtgctggg acccggctca ccgtcctagg tcagcccaag
      301 gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01000330             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:23857:5382
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000330
VERSION     KCVO01000330.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23857:5382"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..427
                     /note="immunoglobulin light chain variable region"
     V_region        104..427
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72359.1"
                     /translation="DYFCCSYADTYTFVF"
     J_segment       404..427
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>472
                     /gene="IGLC"
BASE COUNT           84 a          156 c          120 g          112 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcactca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actttgtctc ctggtaccaa caacatccag gcacagcccc
      241 caaactcatg atttatgagg tcaatcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctcaaagtct ggcaacacgg cctccctgac cgtctccggg gtccaggctg aggacgaggc
      361 tgattatttc tgctgctcat atgcagacac ctacactttt gttttcggaa gtggcaccag
      421 gttgaccgtc gtcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01000331             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:12080:17410
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000331
VERSION     KCVO01000331.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12080:17410"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72360.1"
                     /translation="DYYCSSTDSRDNHRVF"
     J_segment       376..411
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           92 a          139 c          120 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 tttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacgt
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gcagggataa tcatagggta ttcggcggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000332             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:9444:6729
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000332
VERSION     KCVO01000332.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9444:6729"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..441
                     /note="immunoglobulin light chain variable region"
     V_region        113..441
     V_segment       113..407
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72361.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       408..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>481
                     /gene="IGLC"
BASE COUNT           85 a          157 c          127 g          112 t
ORIGIN      
        1 acatgggggc tggtgctggg atctcaggag gcagcactct caggacgtct ccaccatggc
       61 ctgggctctg ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc
      121 cctgactcag tctccctctg tgtctgggtc tcctggacag tcggtcacca tttcctgcac
      181 tggaaccagc agtgacattg gtgattataa ccgtgtctcc tggtaccaac agcacccagg
      241 caaagccccc aaactcatga tttatgaggt cagtgatcgg ccctcagggg tctctgatcg
      301 cttctctggt tccaagtctg gcaacacggc ctccctgatc atctctgggc tccaggctga
      361 ggacgaggct gattattact gcagctcata cactagcagt agcacttggg tattcggcgg
      421 agggacccgg ctgaccgtcc ttggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01000333             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:6692:20511
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000333
VERSION     KCVO01000333.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:6692:20511"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..424
                     /note="immunoglobulin light chain variable region"
     V_region        94..424
     V_segment       94..388
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72362.1"
                     /translation="DYYCSSYADTTTWLF"
     J_segment       389..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           83 a          158 c          116 g          105 t
ORIGIN      
        1 acatggggga ggcagcactc tcaggacgtc tccaccatgg cctgggctct gctcctcctc
       61 accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca gtctccctct
      121 gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag cagtgacatt
      181 ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc caaactcatg
      241 atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg ttccaagtct
      301 ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc tgattattac
      361 tgcagctcat acgcagacac taccacttgg ctattcggcg gagggacccg cctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000334             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:23382:4885
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000334
VERSION     KCVO01000334.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:23382:4885"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..441
                     /note="immunoglobulin light chain variable region"
     V_region        112..441
     V_segment       112..404
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72363.1"
                     /translation="DYHCQSYDSSLSAVLF"
     J_segment       406..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>480
                     /gene="IGLC"
BASE COUNT           90 a          154 c          131 g          105 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacattgg aggttattat gtgcagtggt accagcaagt tccaggaacg
      241 gcccccaaag ctctcatcta tgaaaataat aagcgaccct caggggtttc tgatcgattc
      301 tctggggccc agtctggtac ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt atcactgcca gtcctatgac agcagcctga gtgccgtgtt attcggaggg
      421 gggacccggc tgaccgtcct aagtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000335             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:13674:19804
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000335
VERSION     KCVO01000335.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13674:19804"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72364.1"
                     /translation="DYYCSSTDSRDNHRVF"
     J_segment       376..411
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           92 a          139 c          120 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcgtctat gaggacaaca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacgt
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gtagggataa tcatagggta ttcggcggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000336             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:16760:13348
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000336
VERSION     KCVO01000336.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16760:13348"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..419
                     /note="immunoglobulin light chain variable region"
     V_region        99..419
     V_segment       99..383
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72365.1"
                     /translation="DYYCYSADSSGNGFF"
     J_segment       384..419
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>458
                     /gene="IGLC"
BASE COUNT           96 a          141 c          122 g           99 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcgttgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 cagaaaaata tgcctattgg taccagcaga aaccaggcca gtcccctgta ctgatcatct
      241 atgaggacag caaacggccc tctgggatcc ctgagagatt ctctggctcc agttcaggga
      301 cagtggccac cttgactatc agtggggccc aggtggagga tgaagctgac tactactgtt
      361 actcagcaga cagcagtggt aatggctttt tcggaggagg gacccggctg accgtcctaa
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000337             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:8305:15556
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000337
VERSION     KCVO01000337.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8305:15556"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72366.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       386..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           84 a          142 c          138 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactgcacag actctgtggt ctcctatgaa ttgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacagca
      181 ttggaagtag aagtgtgcag tggtaccagc agaagccacc gcaggccctt ctactggtca
      241 tctttgctga tagcgaacgg ccctcaggga tccctgagcg attctctggc tccaatttag
      301 ggaccaccgc caccctgacc atcagcggcg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatgtgt tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000338             498 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:9844:12133
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000338
VERSION     KCVO01000338.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 498)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9844:12133"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    127..460
                     /note="immunoglobulin light chain variable region"
     V_region        127..460
     V_segment       127..420
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <385..>432
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72367.1"
                     /translation="DYYCSLWDSRLSSRVF"
     J_segment       425..460
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        461..>498
                     /gene="IGLC"
BASE COUNT           96 a          156 c          134 g          112 t
ORIGIN      
        1 acatggggga gatttgggga agctctgctt cagctgtggg cacaggaggc agcactcagg
       61 acagtctcca gcatggcctg gtctctcctt ctcactctgc tggttcactg cacagggtcc
      121 tgggcccagt ctgtgctgac gcagccgccc tcagcatctg gggcccccgg gcagagggtc
      181 accatctcct gcactgggac cagttccaac atcggggcga attattatgt ttcctggtac
      241 cagcagttcc caggaacagc ccccaaactc ctcatctatg aaaacaataa gcgaccctca
      301 ggggtttctg accgattctc tggctccaag tctggtacct cagcctccct gaccatctct
      361 ggactccaat ctgaggatga ggctgattat tactgctcac tatgggatag caggctgagt
      421 agtcgggtat tcggcggagg gacccgactg accgtcctag gtcagcccaa ggctgccccc
      481 tcggtcactc tcttcccg
//
LOCUS       KCVO01000339             414 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:7462:20651
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000339
VERSION     KCVO01000339.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 414)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7462:20651"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..376
                     /note="immunoglobulin light chain variable region"
     V_region        86..376
     V_segment       86..336
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <304..>348
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72368.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       340..376
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        377..>414
                     /gene="IGLC"
BASE COUNT           89 a          127 c          111 g           87 t
ORIGIN      
        1 acatggggtg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactcccca tcctcacttt ctgcacagtg tccccaggac agacggccag gatcacctgc
      121 tctggagatg cattgccaga aaaatatgct tattggtacc agcagaaacc aggccagtcc
      181 cctatgctga tcatctatga ggacagcaaa cggccctctg ggatccctga aagattctct
      241 ggctccagct cagggacagt ggccaccttg actatcactg gggcccaggt ggaggatgaa
      301 gctgactact actgttactc agcagacaac agtggtcagg gctcattcgg aggagggacc
      361 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000340             496 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:9416:11665
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000340
VERSION     KCVO01000340.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 496)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 496)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..496
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9416:11665"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    131..458
                     /note="immunoglobulin light chain variable region"
     V_region        131..458
     V_segment       131..418
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>430
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72369.1"
                     /translation="DYYCYSTDTSDNYRGFF"
     J_segment       422..458
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        459..>496
                     /gene="IGLC"
BASE COUNT          103 a          150 c          135 g          108 t
ORIGIN      
        1 acatggggga agagaagcct agggagccca gctgtgctgt gggctcagga ggcagagctc
       61 tgggtgtctc accatggcct ggattcctct cctactcccc ctcctcactt tctgcacagg
      121 ctctgcagcc tcctatgagc tgacacagcc accctcggtg tcagtgtccc caggacagac
      181 ggccaggatc acctgctctg gagatgcatt gccagaaaaa tttgcttttt ggttccagca
      241 gaagccaggc cagtcccctg tgctgatcat ctatgaggac accaaacggc cctctggaat
      301 ccctgaaaga ttctctggct ccagctcagg gacagtggcc accttgagta tcagtggggc
      361 ccaggtggag gatgaagctg actactactg ttactcaaca gataccagtg ataattatag
      421 gggcttcttc ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc
      481 ggtcactctc ttcccg
//
LOCUS       KCVO01000341             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:21548:10135
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000341
VERSION     KCVO01000341.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:21548:10135"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72370.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           94 a          159 c          122 g          107 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcctcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccgggaa gagtgtcacc atctcctgtt
      181 ctggaagcac ctccaacatc ggaactaata gtgtatcctg gtaccagcag ctcccagaaa
      241 cggctcccaa actcctcatc tattataatg atcgacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg ataacagcct gagcggttac atcttcggtg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCVO01000342             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:18002:3610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000342
VERSION     KCVO01000342.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:18002:3610"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72371.1"
                     /translation="DYYCCSYAGRFTFVF"
     J_segment       404..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           77 a          157 c          125 g          113 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg cctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc gtctcctgca ctggggccag
      181 cagtgacatc ggtggttttg actttgtctc ctggtaccaa cagcgtccag gcacagcccc
      241 caaactcatg atttatgagg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtcc ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgacgc
      361 tgattattat tgctgctcat atgcaggcag gttcactttt gtattcggaa gtggcaccaa
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01000343             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:17395:15974
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000343
VERSION     KCVO01000343.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17395:15974"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..390
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72372.1"
                     /translation="DYSCLSYDSSLSAHYIF"
     J_segment       393..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           91 a          163 c          110 g          104 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctcgtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac acagccaccc
      121 tcagtgtctg gggccccagg gcagagggtc accatctcgt gcactgggag cagctccaac
      181 attggaggtg attctgtatc ctggtaccaa catctcccag gcacgacccc caaactcctc
      241 atctatcaaa ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggtacctcag cctccctgac catcactggg ctccagactg aggatgaggc tgattactcc
      361 tgcctgtcct atgacagcag cctgagtgct cattacatct tcggtcctgg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCVO01000344             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:15975:9496
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000344
VERSION     KCVO01000344.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:15975:9496"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72373.1"
                     /translation="DYYCQVWDSISDHRIF"
     J_segment       397..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          144 c          139 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggttttgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaag taaatatgtg cactggtacc agcagaagcc aacgcaggcc cctgtggtgg
      241 tcatctatta tgatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt attagtgatc atcggatatt cggcggaggg acccggctga
      421 ccgccctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000345             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:17760:7606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000345
VERSION     KCVO01000345.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17760:7606"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..452
                     /note="immunoglobulin light chain variable region"
     V_region        120..452
     V_segment       120..411
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72374.1"
                     /translation="NYYCLSYDTSLSGHGLF"
     J_segment       416..452
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        453..>491
                     /gene="IGLC"
BASE COUNT           95 a          165 c          120 g          111 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg actgtctcca
       61 acatggcctc gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacacagcca ccctcactgt ctggggcccc aggacagagg gtcaccatct
      181 cgttcactgg gagcagctcc aacattggag gttattctgt atcctggtgc cagaaattcc
      241 cagaaacgac ccccaacctc ctcgactatc aagataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtccct cagcctccct gaccatcact gggctccaga
      361 ctgaggctgg gactaattat tactgcctgt cgtatgacac cagcctgagt ggtcatggct
      421 tgttcggagg aggaacccgg ctgaccgtcc tacgtcagcc caaggctgcc ccctcggtca
      481 ctctcttccc g
//
LOCUS       KCVO01000346             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:22841:3929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000346
VERSION     KCVO01000346.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22841:3929"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..263
                     /note="immunoglobulin light chain variable region"
     V_region        8..263
     V_segment       8..225
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72375.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       229..263
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           65 a           85 c           85 g           66 t
ORIGIN      
        1 acatggggga gatgcattgc caaaaaagta tgcttattgg ttccagcaga agccaggcca
       61 gtcccctgtg ctgatcatct atgaggacag cagacggccc tctgggatcc ctgagagatt
      121 ctctgcctcc agctcaggga cagtggccac cttgactatc agtggggccc agggggagga
      181 tgaagctgac tactactgtt attcaatgga tagcagtggt actcagagca tcttcggtgc
      241 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      301 g
//
LOCUS       KCVO01000347             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:28687:8611
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000347
VERSION     KCVO01000347.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:28687:8611"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..385
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72376.1"
                     /translation="DYYCQVWDSSSNVFF"
     J_segment       393..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           87 a          138 c          138 g           98 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactgcacag attctgtggt ctcctatgaa ttgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacagca
      181 ttggaagtag aagtgtgcag tggtaccagc agaagccacc gcaggccctt gtactggtca
      241 tctatgctga tagggaacgg ccctcaggga tccctgagcg attctctggc tccaatttag
      301 ggaacaccgc caccctgacc atcagcggcg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtaatgtat ttttcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000348             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:12735:22350
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000348
VERSION     KCVO01000348.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:12735:22350"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72377.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       402..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           88 a          156 c          121 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tggcctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtaa tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaagacga
      361 ggctgattat tactgcagct catacacaag tagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000349             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:15403:5448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000349
VERSION     KCVO01000349.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15403:5448"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..412
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72378.1"
                     /translation="DYYCQSYDTRLRAWVF"
     J_segment       413..449
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           92 a          159 c          125 g          111 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtcctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcaccatctc
      181 ctgcactggg agcagctcca acattggaga ttattttgtt cagtggtacc aacagcttcc
      241 agcaacggcc cccaaactcc tcatctatga aaatgataaa cggccctcag gagtttctga
      301 tcgattctct ggctcccagt ctggaacctc agcctccctg accatcactg gactccagtc
      361 tgaggatgag gctgattatt actgccagtc ctatgacacc agattgaggg cttgggtttt
      421 cggcggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCVO01000350             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:7633:13318
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000350
VERSION     KCVO01000350.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7633:13318"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72379.1"
                     /translation="DYYCQVWDSNSKYIF"
     J_segment       393..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           92 a          150 c          131 g           91 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca caggctctgc ggcctcctat gacctgactc
      121 agccaccctc ggtgtcggtg tccccaggac agacagccag gatcacctgt gggggagaca
      181 acattggcag taaaagtgtg cactggtacc agcagaggcc accgcaggcc cctgtactgg
      241 tcatatatac tgatagcgaa cggccctcag ggatccctga ccgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cagggatgag gctgactatt
      361 actgtcaggt gtgggacagt aatagtaagt acatcttcgg tgcagggacc cggctcaccg
      421 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCVO01000351             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:22282:13458
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000351
VERSION     KCVO01000351.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:22282:13458"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72380.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          156 c          119 g          109 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatacaa atcagactca gataagggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tggttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000352             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:16008:8676
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000352
VERSION     KCVO01000352.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16008:8676"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72381.1"
                     /translation="DYYCQVWDITTDHDVF"
     J_segment       389..425
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           94 a          137 c          129 g          103 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatgacct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ttctgcggcc tcctatgagc tgactcagtc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaaa aatgtgcact ggcaccagca gaagccaccg caggcccctg ttttggtcat
      241 ctattatgat atcgaacggc cctcagggat ccctgagcga ttctctggcg ccaaatcagg
      301 gaacaccgcc accctgatca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattacta ctgatcatga tgtattcgga agtggcacca agttgaccgt
      421 cctcggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01000353             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1101:13910:10815
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000353
VERSION     KCVO01000353.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:13910:10815"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..390
                     /note="immunoglobulin light chain variable region"
     V_region        114..390
     V_segment       114..348
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <315..>362
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72382.1"
                     /translation="DYFCSVWDSSLTIYIF"
     J_segment       353..390
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        391..>428
                     /gene="IGLC"
BASE COUNT           76 a          141 c          111 g          100 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtccggg gcccagcctg
      121 tgctgacgca gccgccctca gcatctgggg cccccgggca gagggtcacc atctcctgca
      181 ctgggagcag ctccaaactc ctcatctatg aaaataataa gcgaccctca ggggtttctg
      241 accgattctc tggctccaag tctggtacct cagcctccct gactatcact ggactccaat
      301 ctgaggatga ggctgattat ttctgctctg tctgggatag cagcctgact atttacatct
      361 tcggtgctgg gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc
      421 tgttcccg
//
LOCUS       KCVO01000354             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:9863:19552
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000354
VERSION     KCVO01000354.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9863:19552"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72383.1"
                     /translation="DYYCHLYDTTGVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           88 a          163 c          123 g          109 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcac ttgtatgaca ctactggagt gttgttcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01000355             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:11661:11931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000355
VERSION     KCVO01000355.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11661:11931"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..423
                     /note="immunoglobulin light chain variable region"
     V_region        101..423
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72384.1"
                     /translation="DYYCYSSDVSGDHRVF"
     J_segment       390..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>463
                     /gene="IGLC"
BASE COUNT           92 a          140 c          126 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaagac agtaaacggc cctctgggat ccctgagaga ttctctggct ccagttcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcatca gatgtcagtg gtgatcatag ggtattcggc ggagggaccc ggctgaccgt
      421 ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000356             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:6109:22159
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000356
VERSION     KCVO01000356.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:6109:22159"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72385.1"
                     /translation="DYYCQVWDSSSDHPIF"
     J_segment       395..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           81 a          147 c          137 g          102 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagtctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac ggacggccag gatcacctgt gggggagaca
      181 tcgttggaag tgaatatgtt cactggtatc agcagaagtc agcgcaggcc cctgtggtgg
      241 tcatctatta ttattctgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggagcac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactact
      361 actgtcaggt gtgggacagt agtagtgatc atcccatctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01000357             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:21304:17596
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000357
VERSION     KCVO01000357.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:21304:17596"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72386.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          161 c          119 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctccggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000358             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:5238:13057
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000358
VERSION     KCVO01000358.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5238:13057"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72387.1"
                     /translation="DYYCAAWDDSLNSPFF"
     J_segment       401..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           91 a          155 c          117 g          106 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gataatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 accctcaacg tctggggctc ccgggcagag tgtcaccatc tcttgctctg gaagcagctc
      181 caacattgga agtaattatg taaactggta ccagcaactc ccaggaacgg cccccaaact
      241 cctcatctat tttactaatc agcgaccctc aggggtccct gaccgattct ctggctctaa
      301 gtctggcacc tcagcctccc tggccatcac tggtctccga tctgaggatg aggctgatta
      361 ttactgtgcg gcatgggatg acagcctgaa cagtcccttc ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000359             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:6693:11295
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000359
VERSION     KCVO01000359.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:6693:11295"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..400
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72388.1"
                     /translation="NYYCGSYAGSDTFLF"
     J_segment       401..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           85 a          157 c          123 g          107 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcggcactc tcgggacatc tccaccatgg cctgggatct
       61 gctcctcttc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctca atgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaatcag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcacg atttatgacg atagtcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaactcgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 taattattac tgcggctcat atgcaggcag cgacactttc ttattcggag gtgggacccg
      421 gctgaccgtc ctgggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000360             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:8125:21226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000360
VERSION     KCVO01000360.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8125:21226"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72389.1"
                     /translation="DYYCSSYGSSSTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           83 a          156 c          126 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtggtt ataaccgtgt ctcctggttc caacagcacc caggcaaagc
      241 ccccaaactc atgatttacg aggtcagtta tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacggaag cagtagcact tgggttttcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000361             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:19705:17169
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000361
VERSION     KCVO01000361.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19705:17169"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..424
                     /note="immunoglobulin light chain variable region"
     V_region        94..424
     V_segment       94..387
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72390.1"
                     /translation="DYYCAAWDDSLNSPFF"
     J_segment       394..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           89 a          154 c          114 g          105 t
ORIGIN      
        1 acatggggga aggcaggact caggataatc tccagcatgg cctggttccc tctcgtcctc
       61 accctcctca ctcactgtgc agggtcctgg gcccagtctg tgctgactca gccaccctca
      121 acgtctgggg ctcccgggca gagtgtcacc atctcttgct ctggaagcag ctccaacatt
      181 ggaagtaatt atgtaaactg gtaccagcaa ctcccaggaa cggcccccaa actcctcatc
      241 tattttacta atcagcgacc ctcaggggtc cctgaccgat tctctggctc taagtctggc
      301 acctcagcct ccctggccat cactggtctc cgatctgagg atgaggctga ttattactgt
      361 gcggcatggg atgacagcct gaacagtccc ttcttcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000362             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:12424:13581
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000362
VERSION     KCVO01000362.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12424:13581"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72391.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       393..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           89 a          140 c          138 g           96 t
ORIGIN      
        1 acatggggtg gcctcgggaa gcagccttgg cggtgcctca gccatggccg ggacccttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgcggtc tcctatgacc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaatgt
      181 tggaagtgaa tatgtgcact ggtaccaaca gaaaccagcg caggcccctg tggtggtcat
      241 ccattataat agtgaccggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtgatcattg tgtattggga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000363             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:12854:7372
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000363
VERSION     KCVO01000363.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12854:7372"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..395
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72392.1"
                     /translation="DYYCCSYAGRYLF"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           82 a          156 c          126 g          103 t
ORIGIN      
        1 acatgggggg gggtctcaga cggcagcgct ctcgggacat ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctcgctc agtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cggtggttct aactatgtct cctggtacca acagtatcca ggcacagccc
      241 ccaaactcat gatttatgag gtcagtaagc ggccctcagg ggtctcgagt cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgctgctca tatgcaggca ggtacttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000364             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:23853:6356
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000364
VERSION     KCVO01000364.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:23853:6356"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72393.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       375..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           92 a          142 c          116 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct ctgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgtca aaatactatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtggc gatcatctat gaggacaaca
      241 aacggccctc tgggatccct gagagaatct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtcgaggatg aagctgacta ctactgttac tcaacagata
      361 gcagtggtac taatggctta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000365             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:13395:8673
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000365
VERSION     KCVO01000365.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:13395:8673"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..400
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72394.1"
                     /translation="DYYCSSYTDSSTWVF"
     J_segment       401..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           88 a          155 c          124 g          107 t
ORIGIN      
        1 acatgggggg gggatctcag gaggcagcac tctcaggacg tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagtctccct ctgtgtctgg gtctcctgga cagtcggtca ccatttcctg cactggaacc
      181 agcagtgaca ttggtggtta taaccgtgtc tcctggtacc aacagcaccc aggcaaagcc
      241 cccaaactca tgatttatga ggtcaataat cggccctcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg atcatctctg ggttccaggc tgaggacgag
      361 gctgattatt actgcagctc atacacagac agtagcactt gggtattcgg cggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000366             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:23137:4873
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000366
VERSION     KCVO01000366.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:23137:4873"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72395.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       396..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          142 c          139 g           96 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg cttactgcac agactctgcg gtctcctatg acctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 tgttggaagt gaatatgtgc actggtacca acagaaacca gcgcaggccc ctgtggtggt
      241 catccattat aatagtgacc ggccctcagg gatccctgag cgattctctg gctccaaatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta gtagtgatca ttgtgtattg ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000367             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:9486:14792
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000367
VERSION     KCVO01000367.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9486:14792"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72396.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          161 c          119 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc ctttcctgca ctggaaccag
      181 tagtgacatt ggtggttata accgtgtctc ctggtaccaa caccacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac ttccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000368             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:11050:9592
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000368
VERSION     KCVO01000368.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11050:9592"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..427
                     /note="immunoglobulin light chain variable region"
     V_region        104..427
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72397.1"
                     /translation="DYFCCSYADTYTFVF"
     J_segment       404..427
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>472
                     /gene="IGLC"
BASE COUNT           84 a          156 c          120 g          112 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actttgtctc ctggtaccaa caacatccag gcacagcccc
      241 caaactcatg atttatgagg tcaatcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctcaaagtct ggcaacacgg cctccctgac cgtctccggg gtccaggctg aggacgagac
      361 tgattatttc tgctgctcat atgcagacac ctacactttt gttttcggaa gtggcaccag
      421 gttgaccgtc gtcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01000369             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:22361:5998
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000369
VERSION     KCVO01000369.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:22361:5998"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72398.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           95 a          159 c          121 g          107 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcctcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcac ctccaacatc ggaactaata gtgtatcctg gtaccagcag ctcccagaaa
      241 cggctcccaa actcctcatc tattataatg atcgacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg ataacagcct gagcggttac atcttcggtg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCVO01000370             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:7326:23201
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000370
VERSION     KCVO01000370.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7326:23201"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72399.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          160 c          118 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatt atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000371             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:11670:3115
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000371
VERSION     KCVO01000371.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11670:3115"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72400.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       394..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          142 c          138 g           98 t
ORIGIN      
        1 acatgggggc tggcctcggg aagcagcctt ggcggtgcct cagccatggc cgggaccctt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg tctcctatga gctcactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggaggcaat
      181 gttggaagtg aatatgtcca ctggtatcaa cagaagccac cgcaggcccc tgtggtggtc
      241 atctattata atactgaccg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacagtag gagtgatcat agtttattgg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000372             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:11551:12576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000372
VERSION     KCVO01000372.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11551:12576"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..390
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72401.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          152 c          125 g          103 t
ORIGIN      
        1 acatggggga caggaggcgg cactcaggac agtctccagc atggcctggt ctcctctcct
       61 cctcaccctt ctcattcact gcacagggtc ctgggcccag tctgtgctga cgcagccgcc
      121 ctcagtgtct ggggcgcccg ggcagagggt caccatctcc tgcactggga gcagctccaa
      181 cattggaggt tattatgtgc agtggtacca gcagcttcca ggaacggccc ccaaactcct
      241 catgtatgaa aataataagc gaccctcagg ggtttctgat cgattctctg gctcccagtc
      301 tggtgcctca gcctccctga ccatcactgg actccagtct gaggatgagg ctgattatta
      361 ctgccagtcc tatgacagca gcctgagtgc cgtgttattc ggagcaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000373             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:6200:17081
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000373
VERSION     KCVO01000373.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:6200:17081"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..428
                     /note="immunoglobulin light chain variable region"
     V_region        105..428
     V_segment       105..392
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72402.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       397..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>467
                     /gene="IGLC"
BASE COUNT           95 a          143 c          126 g          103 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccctcctc actttctgca caggctctgc agcctcctat gagctgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc gcaggagatg
      181 cattgccaaa aaagtatgct tattggttcc agcagaagcc aggccagtcc cctgtgctga
      241 tcatctatga agacgacaaa cggccctctg ggatccctga gagattctct ggctccagct
      301 cagggacagt ggccaccttg actatcagtg gggcccaggt ggaggatgaa agtgactact
      361 actgttactc aatagatagt agtggtagtc atagcgtctt cggtgctggg acccggctca
      421 ccgtcctacg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01000374             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:13704:17393
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000374
VERSION     KCVO01000374.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13704:17393"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72403.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          157 c          129 g          109 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaggtt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaactcctc atgtatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagact ggtacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cctgagtgcc gtgttattcg
      421 gagtagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01000375             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:14540:11208
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000375
VERSION     KCVO01000375.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14540:11208"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..403
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72404.1"
                     /translation="DYYCSAWDNSLSGYIF"
     J_segment       405..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           87 a          152 c          128 g          113 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc tccttctcac tctgctggtt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagc atctggggcc cccgggcaga gggtcaccat ctcgtgcact
      181 gggagcagct ccaacattgg aggttattct gtatcctggt accggcaacg cccaggagcg
      241 gtccccaaac tcctcatctt tgaaaataat aagcgaccct caggtgtctc tgaccgattc
      301 tctggctcca agtctggtgt ctcagcctcc ctatgcatca ctggactcca gtctgaggat
      361 gaggctgatt attactgctc agcttgggat aacagcctga gtggttacat cttcggtgct
      421 gggacccgag tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01000376             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:13110:7914
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000376
VERSION     KCVO01000376.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:13110:7914"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72405.1"
                     /translation="DYYCQVWDSSSKYAIF"
     J_segment       395..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          149 c          136 g           89 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga ggtgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta gaaatgtcca ctggtaccag cagaagccac cgcaggcccc tgttctggtc
      241 atctatgctg atgccaaacg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtaaatac gcgatattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000377             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:20525:18589
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000377
VERSION     KCVO01000377.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20525:18589"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72406.1"
                     /translation="DYYCYSTDSSGNHGLF"
     J_segment       375..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           94 a          140 c          115 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgtattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagaaattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aatctgacta ctactgctac tcaacagata
      361 gcagtggtaa tcatggctta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000378             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:13511:2428
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000378
VERSION     KCVO01000378.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13511:2428"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72407.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          143 c          126 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgacgac agcaaacggc cctctgggat tcctgagaga ttctctgggt ccagctcagg
      301 gacagtggcc accttgacta tcattggggc ccaggtggag gatgaagctg actaccactg
      361 tttctcaaca gatagcagtg gtaatcatag gggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000379             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:18156:18715
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000379
VERSION     KCVO01000379.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18156:18715"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72408.1"
                     /translation="DYYCYSTRGSGYHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          142 c          124 g          106 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac accaaacggc cctctgggat ctctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtgcag gatgaagctg actactactg
      361 ttactcaact cgtggcagtg gttatcatgg cttattcgga ggagggactt ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000380             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:13580:5357
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000380
VERSION     KCVO01000380.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13580:5357"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72409.1"
                     /translation="DYYCQSYDTRLRAWVF"
     J_segment       406..442
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           93 a          154 c          124 g          109 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagtt ccaatattgg agattatttt gtgcagtggt accaacagct tccaggaacg
      241 gccccccaac tcctcatcta tgaaaatcac aaacgaccct caggaatatc tgatcgattc
      301 tttggttccc agtctggaac ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgcca gtcctatgac accagattga gggcttgggt attcggcgga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000381             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:8144:5005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000381
VERSION     KCVO01000381.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:8144:5005"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72410.1"
                     /translation="DYYCSSTDRSGNHVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          144 c          124 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc ccggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tacgcttatt ggttccaaca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac agcaaacggc cctctgggat tcctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagaagtg gtaatcatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000382             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:6528:20232
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000382
VERSION     KCVO01000382.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6528:20232"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72411.1"
                     /translation="DYYCQVWDSITDHSIF"
     J_segment       394..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          150 c          132 g           98 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg cttactgcac agtctctgcg gtctcctatg agctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggggacaa
      181 cattggaact gaatatgtgc actggtacca gcagaagcca ccgcaggccc ctgtggtggt
      241 catctattat aatactgacc ggccctcagg gatccctgag cgattctcag gctccaaatc
      301 agggaacacc ggcaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta ttactgatca ttccatcttc ggtgctggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctc ttcccg
//
LOCUS       KCVO01000383             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:5360:9416
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000383
VERSION     KCVO01000383.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5360:9416"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72412.1"
                     /translation="DYYCQVWDSSSDHILF"
     J_segment       391..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           86 a          144 c          135 g           98 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatgccg ggacccttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggtc tcctatgagt tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacct
      181 tggagataaa tatgtacact ggtaccagca gaagccaccg cgggcccctg tgctggtcat
      241 ctactatgat agtgaccggc cctcatggat ccctgagcga ttctctgggt ccaaatcagg
      301 gatcaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtgatcatat cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000384             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:20352:8938
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000384
VERSION     KCVO01000384.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20352:8938"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72413.1"
                     /translation="DYYCQVWDSSSDHILF"
     J_segment       392..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           85 a          144 c          137 g           98 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgag ttgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaacc
      181 ttggagataa atatgtacac tggtaccagc agaagccacc gcgggcccct gtgctggtca
      241 tctactatga tagtgaccgg ccctcatgga tccctgggcg attctctggg tccaaatcag
      301 ggatcaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatcata tcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000385             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:7336:9709
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000385
VERSION     KCVO01000385.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7336:9709"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..419
                     /note="immunoglobulin light chain variable region"
     V_region        104..419
     V_segment       104..385
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72414.1"
                     /translation="DYYCQSTDSSGFIF"
     J_segment       388..419
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>460
                     /gene="IGLC"
BASE COUNT          102 a          137 c          119 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 accaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatgctc agtggttcca gcagaagcca ggccaggccc ctgtgttgct
      241 gatatttaaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacatca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca acagacagca gtggtttcat cttcggtgct gggacccggc tcaccgtccc
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01000386             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:17673:15439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000386
VERSION     KCVO01000386.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:17673:15439"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..388
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72415.1"
                     /translation="DYYCLSYDNSLSVYYIF"
     J_segment       393..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           95 a          159 c          109 g          105 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctcgtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtactgac acagccaccc
      121 tcagtgtctg gggccccagg gcagagggtc accatctcgt gcactgggag cagctccagc
      181 attggaggtg attatgtatc ctggtaccaa cagctcccag gaacgacccc caaactcctc
      241 atctatcaaa ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggtacctcag cctccctgac catcactggc ctccagactg aggatgaggc tgattactac
      361 tgcctgtcct atgacaacag cctgagtgtt tattacatct tcggtcctgg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCVO01000387             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:26970:13546
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000387
VERSION     KCVO01000387.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:26970:13546"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72416.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          162 c          124 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acccggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000388             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:14318:15335
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000388
VERSION     KCVO01000388.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14318:15335"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72417.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       397..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          142 c          141 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaagcc agcgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgtgtatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000389             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:23221:9291
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000389
VERSION     KCVO01000389.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23221:9291"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..400
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72418.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       401..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           83 a          152 c          125 g          114 t
ORIGIN      
        1 acatgggggt gggatctcag gaggcagcac tctcaggacg tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagtctccct ctgtgtctgg gtctcctgga cagtcggtca ccatttcctg cactggaacc
      181 agcagtgaca ttggtggttt tgagcgtgtc tcctggtacc aacagcaccc aggcaaagcc
      241 cccaaactct tgatttatga ggtcagttat cggccctcag gggtctctga tcgcttctct
      301 ggttccaagt ctgccaacac ggcctccctg atcatctctg ggctccaggc tgaggacgag
      361 gctgattatt attgcagctc atacacaagt agtagtactt gggtattcgg cggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000390             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:5271:5519
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000390
VERSION     KCVO01000390.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:5271:5519"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72419.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           85 a          160 c          120 g          108 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgac gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacgcaagca ctaccacttg gctattcggc ggagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000391             494 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:10475:16217
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000391
VERSION     KCVO01000391.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 494)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10475:16217"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..456
                     /note="immunoglobulin light chain variable region"
     V_region        123..456
     V_segment       123..414
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72420.1"
                     /translation="NYYCLSYDTSLSGHGLF"
     J_segment       419..456
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>494
                     /gene="IGLC"
BASE COUNT           96 a          164 c          125 g          109 t
ORIGIN      
        1 acatgggggg ggaagctctg cttcagctgt gggcacagga ggcagcactc aggacagtct
       61 ccaacatggc ctcgtctcct ctcctcctca cccttctcat tcactgcaca gggtcctggg
      121 cccagtctgt gctgacacag ccaccctcac tgtctggggc cccagggcag agggtcacca
      181 tctcgtgcac tgggagcagc tccaacattg gcacttattc tgtatcctgg tgccagaagt
      241 tcccagaaac gacccccaac ctcctcgact atcaagataa taagcgaccc tcaggggttt
      301 ctgaccgatt ctctgggtcc aagtctggtc cctcagcctc cctgaccatc actgggctcc
      361 agactgagga tgggactaat tattactgcc tgtcgtatga caccagcctg agtggtcatg
      421 gcttattcgg aggaggaacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg
      481 tcactctctt cccg
//
LOCUS       KCVO01000392             376 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:9925:14300
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000392
VERSION     KCVO01000392.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 376)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9925:14300"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..338
                     /note="immunoglobulin light chain variable region"
     V_region        7..338
     V_segment       7..301
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <266..>310
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72421.1"
                     /translation="DYYCQSADDSYNYIF"
     J_segment       302..338
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        339..>376
                     /gene="IGLC"
BASE COUNT           70 a          124 c           95 g           87 t
ORIGIN      
        1 acatggggtt gtgttcactc agccccattc tgtgtcgggg tctccggggc agacggtcac
       61 catctcctgc acccgcagca gtggcagcat tgacagtgaa tatgtgcggt gttaccagca
      121 gcgcccgggc aatgccccca ccacagtgat ttacaaagat aaccaaagac cctctggggt
      181 ccctgatcgg ttctctggct ccattgacag ctcctccaac tctgcctccc tcgccatctc
      241 tgggctgaag tctgaggacg aggctgacta ctactgtcag tctgctgatg acagctacaa
      301 ttacatcttc ggtgctgggt cccggctcac cgtcctaggt cagcccaagg cttcccccac
      361 ggtcactctg ttcccg
//
LOCUS       KCVO01000393             345 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:15222:10507
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000393
VERSION     KCVO01000393.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 345)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 345)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:15222:10507"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..307
                     /note="immunoglobulin light chain variable region"
     V_region        85..307
     V_segment       85..267
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <229..>279
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72422.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       271..307
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        308..>345
                     /gene="IGLC"
BASE COUNT           68 a          107 c           95 g           75 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacagcag aaggcaggcc agtcccctgt gctgatcatc
      121 tatgaggaca gcaaacggcc ctctgggatc cctgagagat tctctggctc cagttcaggg
      181 acaatggcca ccttgactat cagtggggcc caggtggagg atgacgctga ctactactgt
      241 tactcaacag ataacagtga tactcatagg ggcttcttcg gaggagggac ccggctgacc
      301 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000394             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:15881:11553
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000394
VERSION     KCVO01000394.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15881:11553"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72423.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       397..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           91 a          142 c          138 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagactctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaaacc agcgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cgaccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgtgtatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000395             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:28038:11735
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000395
VERSION     KCVO01000395.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:28038:11735"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..393
                     /gene="IGLV7-56"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72424.1"
                     /translation="EYYCWLYYSGAWVF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          153 c          123 g          103 t
ORIGIN      
        1 acatggggtc tggagccagg gatcccttcc aataccagca ccatggcctg gactctgctc
       61 ctcctccagt tcctcctcac ttgctgccca gggtccaatt ctcaggctgt agtgactcag
      121 gagccctcac tgactgtgtc cccagggggg acagtcactc tcacctgtgc ttccagtact
      181 ggagcagtca ccagtggtca ctatccaaac tggtaccagc agaaacctgg acaagccccc
      241 aagacactga tttatgatac aagcaacaag ctctcctgga cccctgcccg gttctcaggc
      301 tcccttgctg ggggtaaagc tgccctgaca ctttcgggtg cgcagcctga ggacgaggct
      361 gagtattact gctggctgta ctacagtggt gcttgggtat tcggcggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000396             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:17341:15961
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000396
VERSION     KCVO01000396.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:17341:15961"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72425.1"
                     /translation="DYYCAAWDDSLSSPLF"
     J_segment       393..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          148 c          117 g          110 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgtagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagtttcaac
      181 attggaagta attatgtaaa ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 atctatttta gtaatcagcg gccctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcat gggatgatag tctgagcagt cccttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000397             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:5680:14832
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000397
VERSION     KCVO01000397.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:5680:14832"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72426.1"
                     /translation="DYYCGSYRRGSTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           83 a          152 c          133 g          107 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcgggac gtctccacca tggcttgggc
       61 tctggtcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtccgtc accatcccct gcactggaac
      181 caagagtgac attggtggtt ataacggtgt ctcctggtac caacagtatt caggcacagc
      241 ccccagactc ctgatttatg aggtcagtca gcggccctca ggggtctctg atcgcttctc
      301 tgggtacaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgcggct catataggag gggaagcact tgggtgttcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000398             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:12504:14371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000398
VERSION     KCVO01000398.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:12504:14371"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72427.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       391..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          144 c          125 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 accaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcagacggc cctctgggat ccctgagaga ttctctgcct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccagggggag gatgaagctg actactactg
      361 ttattcaatg gatagcagtg gtactcagag catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000399             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:18688:10780
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000399
VERSION     KCVO01000399.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18688:10780"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72428.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           95 a          142 c          124 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagac
      121 tccctcggtg tcagtgtccc caggacagac ggccaggatc tcctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaaggcaggc cagtcccctg tgctgatcat
      241 ctatgaggac aacaaacggc cctctgggat ccctgagaga ttctctggct ccagttcagg
      301 gacaatggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gataacagtg atactcatag gggcttcttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000400             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:19378:19281
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000400
VERSION     KCVO01000400.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:19378:19281"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72429.1"
                     /translation="DYFCYSTENSGTHRGFF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           92 a          142 c          118 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag gcaggccagt cccctgtgct gatcatctat gaggacaaca
      241 aacggccctc tgggatccct gagagattct ctggctccag ttcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta cttctgttac tcaacagaaa
      361 acagtggtac tcacaggggc ttcttcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000401             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:12983:12188
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000401
VERSION     KCVO01000401.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12983:12188"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..416
                     /note="immunoglobulin light chain variable region"
     V_region        86..416
     V_segment       86..380
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72430.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       381..416
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           81 a          156 c          112 g          105 t
ORIGIN      
        1 acatggggac tctcaggacg tctccaccat ggcctgggct ctgctcctcc tcaccctcct
       61 cactcagggc acaggatcct gggctcaggc tgccctgact cagtctccct ctgtgtctgg
      121 gtctcctgga cagtcggtca ccatttcctg cactggaacc agcagtgaca ttggtggtta
      181 taaccgtgtc tcctggtacc aacagcaccc aggcaaagcc cccaaactca tgatttatga
      241 cgtcagtgat cggccctcag gggtctctga tcgcttctct ggttccaagt ctggcaacac
      301 ggcctccctg atcatctctg ggctccaggc tgaggacgag gctgattatt actgcagctc
      361 atacgcaagc actaccactt ggctattcgg cggagggacc cgcctgaccg tcctaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000402             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:13005:9738
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000402
VERSION     KCVO01000402.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13005:9738"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72431.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          143 c          139 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctcactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggaggca
      181 atgttggaag tgaatatgtc cactggtatc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatctatta taatactgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt aggagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000403             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:6572:15229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000403
VERSION     KCVO01000403.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6572:15229"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72432.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       418..450
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           91 a          157 c          132 g          108 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggaccc cgggcagagg gtcaccatct
      181 cgtgcactgg gagcagttcc aacattggag gttattttgt atactggtac cagcagttcc
      241 caggaacagc ccccaaactc ctcatctatg acaataataa gcgaccctca gggatttctg
      301 accgattctc tggctccaag tctgggacct cagcctccct gaccatcact gggctccagc
      361 ctggggatga ggctgattat tactgcggag catgggatag cagcctgagt gctcgcttat
      421 tcggcggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCVO01000404             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:19059:14846
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000404
VERSION     KCVO01000404.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19059:14846"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72433.1"
                     /translation="DYYCYSTVSSGNDRIF"
     J_segment       392..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           94 a          143 c          124 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ctctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gttagcagtg gtaatgatag gatcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000405             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:9199:11031
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000405
VERSION     KCVO01000405.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:9199:11031"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..265
                     /note="immunoglobulin light chain variable region"
     V_region        1..265
     V_segment       1..228
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <190..>237
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72434.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       232..265
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        266..>303
                     /gene="IGLC"
BASE COUNT           65 a           82 c           93 g           63 t
ORIGIN      
        1 acatgggtgg gagacaatgt tggaagtgaa tatgtgcact ggtaccaaca gaagccaccg
       61 caggcccctg tggtggtcat ccattataat agtgaccggc cctcagggat ccctgaacga
      121 ttctctggct ccaaatcagg gagcgccgcc accctgacca tcagcggggt cgaggccggg
      181 gatgaggctg actattactg tcaggtgtgg gacagtagta gtgatcatag tttattggga
      241 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      301 ccg
//
LOCUS       KCVO01000406             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:8337:5502
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000406
VERSION     KCVO01000406.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8337:5502"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72435.1"
                     /translation="DYYCQVWDSSSKYIF"
     J_segment       392..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          148 c          132 g           95 t
ORIGIN      
        1 acatgggggc ctgactttgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactgcac aggctctgcg gcctcctatg acctgactca
      121 gccaccctcg gtgtcggtgt ccccaggaca gacagccagg atcacctgtg ggggagacaa
      181 cattggaagt aaaagtgtgc actggtacca ccagaggcca ccgcaggccc ctgtcctggt
      241 catatatact gatagcgaac ggccctcagg gatccctgac cgattctctg gctccaactc
      301 agggaatacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgattatta
      361 ctgtcaggtg tgggacagta gtagtaagta catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggttt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000407             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:7391:10221
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000407
VERSION     KCVO01000407.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:7391:10221"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72436.1"
                     /translation="DYYCYSTDSSGNALF"
     J_segment       388..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           96 a          142 c          123 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tccaatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tttgcttatt ggtaccagca gaaaccaggc cagtcccctg tgctgatcat
      241 gtatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccacctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gacagcagtg gtaatgcctt attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000408             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:16317:10849
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000408
VERSION     KCVO01000408.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:16317:10849"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72437.1"
                     /translation="DYYCSSYTSTSTWVF"
     J_segment       402..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           86 a          158 c          122 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacaacacc caggcaaagc
      241 ccccaaactc atgatttctg aggtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacacaag cactagcact tgggtattcg gcggagggac
      421 ccggctgacc gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000409             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:9751:11730
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000409
VERSION     KCVO01000409.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9751:11730"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72438.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           81 a          157 c          124 g          111 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctgggc agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggttcca acagcaccca ggcaaagccc
      241 ccaaactcat gatttgtgac gtcagtaatc ggccctcagg ggtctctgct cgcttctctg
      301 gttccaagtc tggcaatacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacgcaagca gtagcacttg ggttttcggc ggagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000410             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:13062:19634
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000410
VERSION     KCVO01000410.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13062:19634"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72439.1"
                     /translation="DYYCQVYDGSAWVF"
     J_segment       409..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           87 a          160 c          126 g          110 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gctgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagaagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctct actacttctc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgatcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgacg gtagtgcttg ggtattcggc
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01000411             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:14734:15424
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000411
VERSION     KCVO01000411.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:14734:15424"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72440.1"
                     /translation="DYYCQSGDSSANHYIF"
     J_segment       392..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          103 a          138 c          123 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatgctc ggtggttcca gcagaagcca ggccaggccc ctgtgctggt
      241 gatatataaa gacactgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaata cttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca ggggacagca gtgctaatca ttacatcttc ggtgctggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCVO01000412             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:21986:20968
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000412
VERSION     KCVO01000412.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21986:20968"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72441.1"
                     /translation="DYYCHSLDTSGNDVF"
     J_segment       392..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           90 a          143 c          124 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatacatt
      181 gccaaaaaaa tttgcttact ggttccagca gaagccaggc cagtcccctg tggtgatcat
      241 ctatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 tcattcatta gataccagtg gtaatgatgt tttcggcggg gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000413             311 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:26636:16746
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000413
VERSION     KCVO01000413.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 311)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 311)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..311
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:26636:16746"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..271
                     /note="immunoglobulin light chain variable region"
     V_region        8..271
     V_segment       8..230
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <198..>245
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72442.1"
                     /translation="DYYCQVWDSSSAHWVF"
     J_segment       236..271
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        272..>311
                     /gene="IGLC"
BASE COUNT           62 a           89 c           98 g           62 t
ORIGIN      
        1 acatgggcac ctgtggggga gacaacattg gaagtaaaag tgtgcagtgg ttccagcaga
       61 agccaccgca ggcccctgtg ctggtcattt atggtgatag cgaacggccc tcagggatcc
      121 ctgagcgatt ctctggctcc aactcaggga acaccgccac cctgaccatc agcggggtcg
      181 aggccgggaa tgaggctgac tattactgtc aggtgtggga cagtagtagt gctcattggg
      241 tattcggcgg agggacccgg ctgaccgtcc tcggtcagcc caaggctgcc ccctcggtca
      301 ctctcttccc g
//
LOCUS       KCVO01000414             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:16107:20737
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000414
VERSION     KCVO01000414.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16107:20737"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72443.1"
                     /translation="DYYCCSYRSGNTYVF"
     J_segment       402..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          154 c          126 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcgggac gtctccacca tggcctgggc
       61 tctgctcctc ctcagcctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt ataatgacgt ctcctggtac caccagcacg caggcacagc
      241 ccccagactc ctgatttatg atgtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct ggccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgctgct catataggag tggaaacact tatgtgttcg gaagtggcac
      421 caagttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01000415             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:8718:6044
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000415
VERSION     KCVO01000415.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8718:6044"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72444.1"
                     /translation="DYYCSSYASSSSWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           80 a          155 c          126 g          111 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggttccaa cagcacccag gcaaagcccc
      241 caaactcatg atttgtgacg tcagtgatcg gccctcaggg gtctctgctc gcttctctgg
      301 ttccaagtct ggcaatacgg cctccctgat catctctggg ctccgggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcag tagttcttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000416             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:10387:9802
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000416
VERSION     KCVO01000416.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10387:9802"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72445.1"
                     /translation="DYYCQVWDSSSDHPIF"
     J_segment       395..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           82 a          145 c          136 g          104 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagtgtttgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac ggacggccat gatcacctgt gggggagaca
      181 tcgttggaag tgaatatgtt cactggtatc agcagaagtc agcgcaggcc cctgtggtgg
      241 tcatctatta ttattctgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactact
      361 actgtcaggt gtgggacagt agtagtgatc atcccatctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01000417             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:11355:18204
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000417
VERSION     KCVO01000417.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11355:18204"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72446.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       375..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           91 a          143 c          116 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct ctgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaaa tgcattgcca aaatactatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtggc gatcatctat gaggacagca
      241 aacggccctc tgcgatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtagaggatg aggctgacta ctactgttac tcaacagata
      361 gcagtggtac taatggctta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000418             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:14730:4568
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000418
VERSION     KCVO01000418.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14730:4568"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72447.1"
                     /translation="DYYCCSYAGRFTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           82 a          159 c          122 g          112 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactgggac
      181 cagcagtgac atcggtgatt atgactttgt ctcctggtac caacagcatc caggcacagc
      241 ccccaaactc ataatttatg aggtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tccggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 cgctgattat tactgctgct catatgcagg caggttcact tttgtgttcg gaagtggcac
      421 cagcttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01000419             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:5731:8915
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000419
VERSION     KCVO01000419.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5731:8915"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72448.1"
                     /translation="DYYCSSTDTRDNHRVF"
     J_segment       376..411
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           94 a          141 c          118 g           96 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggac tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 gttattggtt ccaacagaag ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacgt
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 ccagggataa tcatagggta ttcggcggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000420             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:9344:16568
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000420
VERSION     KCVO01000420.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9344:16568"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    133..454
                     /note="immunoglobulin light chain variable region"
     V_region        133..454
     V_segment       133..414
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <382..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72449.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       418..454
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT          107 a          150 c          132 g          103 t
ORIGIN      
        1 acatggggaa taagagaagc ctagggagcc cagctgtgct gtgggctcag gaggcagagc
       61 tctgggtgtc tcaccatggc ctggattcct ctcctactcc ccatcctcac tttctgcaca
      121 ggctctgcag cctcctatga gctgacacag ccaccctcgt tgtcagtgtc cccaggacag
      181 acggccagga tcacctgctc tggagatgca ttgccagaaa aatatgctta ttggtaccag
      241 cagaaaccag gccagtcccc tatgctgatc atctatgagg acagcaaacg gccctctggg
      301 atccctgaaa gattctctgg ctccagctca gggacagtgg ccaccttgat tatcactggg
      361 gcccaggtgg aggatgaagc tgactactac tgttactcag cagacaacag tggtcagggc
      421 tcattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      481 actctcttcc cg
//
LOCUS       KCVO01000421             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:16731:16962
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000421
VERSION     KCVO01000421.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16731:16962"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..432
                     /note="immunoglobulin light chain variable region"
     V_region        105..432
     V_segment       105..397
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72450.1"
                     /translation="DYYCLLYSSGVHLF"
     J_segment       399..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           96 a          157 c          114 g          103 t
ORIGIN      
        1 acatgggggc tctggagcca gagatccctt ccaataccag caccatggcc tggactctgc
       61 tcctcctcca gttcctcctc acttgctgcc cagggtccaa ttctcaggct gtagtgactc
      121 aggagccctc aatgactgtg tccccaggag ggacagtcac tctcacctgt ggctccagca
      181 ctggagcagt caccagtagt aactttccaa actggttcca gcagaaacct ggacaagtcc
      241 ccaggggact catttacaat acacacaaca aacactcctg gacccctgcc cggttctcag
      301 gctccctcgc tggggccaaa gctgccctga cactgtcagg tgcacagccc gaggacgagg
      361 ctgactatta ctgcttgctg tattctagtg gtgttcattt attcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000422             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:21937:5130
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000422
VERSION     KCVO01000422.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:21937:5130"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72451.1"
                     /translation="DYYCQVWDSSTNHILF"
     J_segment       396..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          148 c          134 g           97 t
ORIGIN      
        1 acatggggca gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acaggctctg cggtctccta tgagctgact
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 aaccttgcag atgaatatgt acactggtac cagcagaagc cagcgcgggc ccctttactg
      241 gtcatctact atgatagtga ccggccctca tggatccctg agcgattctc tgggtccaaa
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag tagtactaat catatcttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000423             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:11157:9223
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000423
VERSION     KCVO01000423.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11157:9223"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..379
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72452.1"
                     /translation="DYYCQVWDSITAQWVF"
     J_segment       388..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           83 a          146 c          139 g           94 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctgcacaggc tttgcggtct cctatgagct gactcagcca
      121 cgctcagtgt ccgtgtcccc aggacagacg gcccggatca cctgtggggg agacaacatt
      181 ggaagtaaaa gtgtgcagtg gttccagcag aggccaccgc aggcccctgt gctggtcatt
      241 tatactgata accagcggcc ctcagggatc cctgagcgat tctctggctc caactcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccggga atgaggctga ctattattgt
      361 caggtgtggg acagtattac tgctcagtgg gtattcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000424             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:22175:8166
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000424
VERSION     KCVO01000424.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22175:8166"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72453.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       397..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          143 c          140 g           97 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acaggctctg cggtctccta tgacctgact
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg tgtgggagac
      181 aatgttggaa gtgaatatgt gcactggtac caacagaagc caccgcaggc ccctgtggtg
      241 gtcatccatt ataatagtga ccggccctca gggatccctg aacgattctc tggctccaaa
      301 tcagggagcg ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag tagtagtgat catagtttat tgggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000425             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:11524:16525
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000425
VERSION     KCVO01000425.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11524:16525"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72454.1"
                     /translation="DYYCYSTHSSGNHRVF"
     J_segment       388..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           95 a          142 c          123 g          101 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgaactg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcatttc
      181 caaaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgtg ctgatcgtct
      241 atgaggacag caaacggccc tctgggatcc ctgagagatt ctctgcctcc agctcaggga
      301 cagtggccac cttgactata agtggggccc aggtggagga tgaagctgac tactactgtt
      361 actcaacaca tagtagtggt aatcataggg tgttcggcgg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000426             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:11235:7251
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000426
VERSION     KCVO01000426.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11235:7251"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..426
                     /note="immunoglobulin light chain variable region"
     V_region        99..426
     V_segment       99..391
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72455.1"
                     /translation="DYYCLLYSSGVHLF"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           96 a          155 c          112 g          101 t
ORIGIN      
        1 acatggggga gccagagatc ccttccaata ccagcaccat ggcctggact ctgctcctcc
       61 tccagttcct cctcacttgc tgcccagggt ccaattctca ggctgtagtg actcaggagc
      121 cctcaatgac tgtgtcccca ggagggacag tcactctcac ctgtggctcc agcactggag
      181 cagtcaccag tagtaacttt ccaaactggt tccagcagaa acctggacaa gtccccaggg
      241 gactcattta caatacacac aacaaacact cctggacccc tgcccggttc tcaggctccc
      301 tcgctggggc caaagctgcc ctgacactgt caggtgcaca gcccgaggac gaggctgact
      361 attactgctt gctgtattct agtggtgttc atttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000427             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:28365:7952
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000427
VERSION     KCVO01000427.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:28365:7952"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72456.1"
                     /translation="DYYCSSTDSRDNHRVF"
     J_segment       376..411
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           92 a          139 c          119 g           99 t
ORIGIN      
        1 tcaggaggca gagctcttgg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagatttt ctggctccag ctcagggaca gtggccacgt
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gcagggataa tcatagggta ttcggcggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000428             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:17298:10180
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000428
VERSION     KCVO01000428.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17298:10180"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..429
                     /note="immunoglobulin light chain variable region"
     V_region        103..429
     V_segment       103..398
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72457.1"
                     /translation="DYFCSSYTGSITLF"
     J_segment       399..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>468
                     /gene="IGLC"
BASE COUNT           86 a          157 c          117 g          108 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcgctct caggacgtct ccaccatggt ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 cctccctctg tgtctgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgacatcg gtggttataa ctatgtctcc tggtaccaac ggcacccagg caaagccccc
      241 aaactcatga tttatgatgt caataagcgg ccctcagggg tctctgatcg cttctctggc
      301 tccaaatctg gcaacacggc ctccctgacc atctctgggc tccagtctga ggatgaggct
      361 gattatttct gcagctcata tacaggcagc atcactttat tcggaggagg gacccggctg
      421 accgtcctac gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000429             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:3240:18519
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000429
VERSION     KCVO01000429.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:3240:18519"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..393
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72458.1"
                     /translation="DYYCQVWDSTSKYIF"
     J_segment       394..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          150 c          134 g           94 t
ORIGIN      
        1 acatggggga gcctgacttt gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgctcactgc acaggctctg cggcctccta tgacctgact
      121 cagccaccct cggtgtcggt gtccccagga cagacagcca ggatcacctg tgggggagac
      181 aacattggaa gtaaaagtgt gcactggtac cagctgaggc caccgcaggc ccctgtgctg
      241 gtcatatata ctgatagcga gcggccctca gggatccctg accgattctc tggctccaac
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tttgggacag tactagtaag tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCVO01000430             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:12578:12990
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000430
VERSION     KCVO01000430.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:12578:12990"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72459.1"
                     /translation="DYYCQVWDSSSDHCLL"
     J_segment       392..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           86 a          141 c          139 g           97 t
ORIGIN      
        1 acatggggtg gcctcgggaa gcagccttgg cggtgcctca gccatggccg ggacccttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggtc tcctatgacc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaatgt
      181 tggaagtgaa tatgtgcact ggtaccaaca gaggccaccg caggcccctg tggtggtcat
      241 ccattataat agtgaccggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtgatcattg tttattggga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000431             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:14597:12089
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000431
VERSION     KCVO01000431.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:14597:12089"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72460.1"
                     /translation="DYYCSAWDDSLSSPLF"
     J_segment       409..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           94 a          158 c          119 g          110 t
ORIGIN      
        1 acatggggac cttcagctgc gggtacagaa ggcaggactc aggataatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag ccaccctcaa cgtctggggc tcccgggcag agtgtcacca tctcttgctc
      181 tggaagcaac tccaacattg gaagtaatta tgtaaactgg taccagcagc tcccaggaac
      241 ggcccccaaa ctcctcatct attttagtaa tcagcgaccc tcaggggtcc ctgaccgatt
      301 ctctggctct aagtctggca cctcagcctc cctggccatc actggtctcc gatctgagga
      361 tgaggctgat tattactgtt cagcatggga tgacagcctg agcagtccct tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01000432             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:25724:22275
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000432
VERSION     KCVO01000432.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25724:22275"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..384
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72461.1"
                     /translation="DYYCYSIDSSGNRSFF"
     J_segment       388..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           97 a          139 c          122 g          103 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 caaaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgtg ttgatcatct
      241 atgaggacaa caaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgacaatc agtggggccc aggtggagga tgaaactgac tactactgtt
      361 attcaataga tagtagtggt aatcgtagct tcttcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000433             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:7384:11809
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000433
VERSION     KCVO01000433.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:7384:11809"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72462.1"
                     /translation="DYYCQSADSSGNHPVF"
     J_segment       394..428
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          105 a          135 c          123 g          103 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aactatgctc agtggttcca gcagaagcca ggccaggccc ctatgttggt
      241 gacatataaa gatagtgaga ggcgctcagg gacccctgag cgattctcta gctccagttc
      301 agggacaaca cttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gcagacagca gtggtaatca tcctgtgttc ggaagtggca ccaagttgac
      421 cgtcctcggt cagcccaagg cttccccctt ggtcactctg ttcccg
//
LOCUS       KCVO01000434             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:5691:5282
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000434
VERSION     KCVO01000434.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:5691:5282"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72463.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       392..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           90 a          144 c          125 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tttgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagcagtg gtaatcatgt tttcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000435             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:20169:8000
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000435
VERSION     KCVO01000435.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20169:8000"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72464.1"
                     /translation="DYYCQVWDSSSDHCLL"
     J_segment       397..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           87 a          143 c          141 g           97 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acaggctctg cggtctccta tgacctgact
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 aatgttggaa gtgaatatgt gcactggtac caacagaggc caccgcaggc ccctgtggtg
      241 gtcatccatt ataatagtga ccggccctca gggatccctg agcgattctc tggctccaaa
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag tagtagtgat cattgtttat tgggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000436             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:13382:16240
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000436
VERSION     KCVO01000436.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13382:16240"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72465.1"
                     /translation="DYYCSSTDTSGNHVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           90 a          143 c          116 g           97 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatcaat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aaggtgacta ctactgttcc tcaacagata
      361 ccagtggtaa tcatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000437             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:23521:16084
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000437
VERSION     KCVO01000437.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:23521:16084"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..208
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72466.1"
                     /translation="DYYCQVWDSSSDHWVF"
     J_segment       214..251
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           57 a           87 c           85 g           60 t
ORIGIN      
        1 acatggggga agtaaaagtg tgcagtggtt ccagcagatg ccaccgcagg cccctgtact
       61 ggtcatttat tctgataccg aacggccctc agggatccct gaccgattct ctggctccaa
      121 ctcagggaac accgccaccc tgaccatcag cggggtcgag gccggcaatg aggctgacta
      181 ttactgtcag gtgtgggaca gtagtagtga tcattgggtc ttcggcggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000438             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:17143:7593
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000438
VERSION     KCVO01000438.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:17143:7593"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72467.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          156 c          128 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cgggagtaac agtgtgtcct ggtacctgca gctcccagaa
      241 acggctccca aactcctcat ctattataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cccgtcagcc tccctggcca tcactgggct cgagaccgaa
      361 gatgaggctg attattactg cgcagtatgg gatgatagcc tgagcggtgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01000439             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:18305:12338
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000439
VERSION     KCVO01000439.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18305:12338"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..430
                     /note="immunoglobulin light chain variable region"
     V_region        85..430
     V_segment       85..391
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72468.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          157 c          119 g          104 t
ORIGIN      
        1 acatggggag aggtagccgt gtccaccatg gccctgactc ctctcctcct cctgctcctc
       61 tctcactgca caggttccct ctcccagcct gtgctgactc agccaccctc cctgtctgca
      121 tccccgggag catcggccag actcccctgc accctgagca gtgacctcag tgttggtagt
      181 aaaaacatgt actggtacca gcagaagcca gggagcgctc ccaggttatt cctgtactac
      241 tactccgact cagacaagca gctgggacct ggggtcccca atcgagtctc tggctccaag
      301 gagacctcaa gtaacacagc gtttttgctc atctctgggc tccagcctga ggacgaggcc
      361 gattattact gtcaggtgta tgacagtact ggagtgttgt tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000440             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:9166:18172
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000440
VERSION     KCVO01000440.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9166:18172"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..443
                     /note="immunoglobulin light chain variable region"
     V_region        112..443
     V_segment       112..403
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <367..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72469.1"
                     /translation="DYYCQSSDTSLNDHVLF"
     J_segment       408..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>483
                     /gene="IGLC"
BASE COUNT           95 a          158 c          118 g          112 t
ORIGIN      
        1 acatgggggc ttcatctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tcgtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacacagc cgccctcagt gtctggggcc ccagggcaga gggtcaccat ctcctgcact
      181 gggagcagtt ccaacattgg aggttattat gtatattggt accagcaact cccaggaatg
      241 gcccccaaac tcctcatcta tgacaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggttc ctcagcctcc ctgaccatca ctgggctcca gactgaggat
      361 gaggctgatt attactgcca atcctctgac accagcctaa atgatcatgt gttattcgga
      421 ggagggaccc ggctgaccgt cctcggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01000441             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:16553:10241
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000441
VERSION     KCVO01000441.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16553:10241"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72470.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           97 a          144 c          120 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggtaccagca gaaaccaggc cagtccccta tgctgatcat
      241 ctatgaggac agcaaacggc cctctggtat ccctgaaaga ttctctgcct ccagctcagg
      301 gacagtggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 ttattcagca gacaacagtg gtcagggctc attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000442             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:14890:7993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000442
VERSION     KCVO01000442.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14890:7993"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..420
                     /note="immunoglobulin light chain variable region"
     V_region        101..420
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72471.1"
                     /translation="DYYCYSTDTSAFHVF"
     J_segment       389..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>460
                     /gene="IGLC"
BASE COUNT           90 a          142 c          124 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agtaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggtc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gataccagtg cttttcatgt attcggcgga gggacccggc tgaccgtcct
      421 gggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000443             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:7590:3753
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000443
VERSION     KCVO01000443.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7590:3753"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72472.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          154 c          123 g          109 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca gtagtacttg ggtattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000444             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:13327:12125
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000444
VERSION     KCVO01000444.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13327:12125"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72473.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           90 a          140 c          117 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcacaag ccaggccagt cccctgtgct gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gggagattct ctggctccag ctcagggaca gtggccacat
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gtagtggtaa ttatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000445             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:22318:4683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000445
VERSION     KCVO01000445.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22318:4683"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72474.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          161 c          124 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000446             506 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:19583:17437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000446
VERSION     KCVO01000446.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 506)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 506)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..506
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19583:17437"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    138..468
                     /note="immunoglobulin light chain variable region"
     V_region        138..468
     V_segment       138..431
                     /gene="IGLV8-111"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <396..>440
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72475.1"
                     /translation="DYYCSLYMGSGISVF"
     J_segment       434..468
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        469..>506
                     /gene="IGLC"
BASE COUNT          103 a          156 c          127 g          120 t
ORIGIN      
        1 acatggggga aaaggccctg aggaaaacaa actccagctg agaagcctga gagcacttgg
       61 ccttcataag tgtccccacc atggcctgga tgatgcttct cctcggactc cttgcttatg
      121 gctcaggagt ggattctgag actgtggtga cccaggagcc atcgttgtca gtgtcccctg
      181 gaggaacagt cacactcacc tgtggcctga actctggctc agtctctatc agtaactacc
      241 ccagctggta ccagcagacc ccaggccagg ctccacgcat gctcatcttc agcacaaaca
      301 gtcgcccttc tggggtccct gatcgcttct ctggctccat ccttgggaac aaagctgccc
      361 tcaccatcac gggggctcgg acagacgatg actctgatta ttactgttcc ctctacatgg
      421 gtagtggcat ttctgtgttc ggaagtggca ccaagttgac cgtcctcggt cagcctaagg
      481 cttccccctt ggtcactctg ttcccg
//
LOCUS       KCVO01000447             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:23795:22163
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000447
VERSION     KCVO01000447.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:23795:22163"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72476.1"
                     /translation="DYYCQVWDITTDHDVF"
     J_segment       390..426
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           94 a          137 c          130 g          103 t
ORIGIN      
        1 acatggggtg ggcctcagga ggcagcattg acggtgcctc agccatgacc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gttctgcggc ctcctatgag ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacgaca
      181 ttggaagtaa aaatgttcac tggtaccagc agaagccacc gcaggcccct gtattggtca
      241 tctattatga tagcaaacgg ccctcaggga tccctgagcg attctctggc gccaaatcag
      301 ggaacaccgc caccctgatc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacattact actgatcatg atgtgttcgg aagtggcacc aagttgaccg
      421 tcctcggtca gcccaaggct tcccccttgg tcactctgtt cccg
//
LOCUS       KCVO01000448             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:19020:16910
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000448
VERSION     KCVO01000448.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19020:16910"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..263
                     /note="immunoglobulin light chain variable region"
     V_region        4..263
     V_segment       4..226
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72477.1"
                     /translation="DYYCQVWDSSSKYAIF"
     J_segment       231..263
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           66 a           90 c           88 g           57 t
ORIGIN      
        1 acatggggga gacaacattg gaagtagaaa tgtccactgg taccagcaga agccaccgca
       61 ggcccctgtt ctggtcatct atgctgatgc caaacggccc tcagggatcc ctgagcgatt
      121 ctctggctcc aactcaggga acaccgccac cctgaccatc agcggggtcg aggccgggga
      181 tgaggctgac tattactgtc aggtgtggga cagtagtagt aaatacgcga tattcggcgg
      241 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCVO01000449             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:24162:11214
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000449
VERSION     KCVO01000449.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:24162:11214"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72478.1"
                     /translation="DYYCYATDSSGYRGLF"
     J_segment       388..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          140 c          131 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gggatgcatt
      181 gccgaaaaat tatgcttatt ggttccggca gaagccaggc cagtcccctg tgatgatcat
      241 ctatgaggac agcaaacggc cgtctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttacgcaaca gatagcagtg gttatcgtgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000450             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:4154:12395
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000450
VERSION     KCVO01000450.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:4154:12395"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72479.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          144 c          126 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctctgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gaaatgcatt
      181 gccagaatac tatgcttatt ggttccagca gaagccaggc cagtcccctg tggcgatcat
      241 ctatgaggac aacaaacggc cctctgggat ccctgagaga ttctctggcg ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtagag gatgaggctg actactactg
      361 ttactcaaca gatagcagtg gtactaatgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000451             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:19139:17540
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000451
VERSION     KCVO01000451.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19139:17540"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72480.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       391..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          141 c          139 g           96 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag ggtctgcggt ctcctatgag ctcactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggaggcaatg
      181 ttggaagtga atatgtccac tggtatcaac agaagccacc gcaggcccct atggtggtca
      241 tctattataa tagtgaccgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagg agtgatcata gcttattggg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000452             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:13685:10214
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000452
VERSION     KCVO01000452.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13685:10214"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72481.1"
                     /translation="DYYCQVWDSSSDHYIF"
     J_segment       393..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          142 c          140 g           98 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgc ggcctcctat gagctgactc
      121 agccacgctc ggtgtcggtg tcccagggac agacggccag gatcacctgt gggggagaca
      181 acattggaag tgaagctgtg cagtggtacc agcagaagcc agcgcaggcc cctgtgctgg
      241 tcatctatga tgatagcgaa cggccctcag ggatccctga tcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggatagt agtagtgatc attacatctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01000453             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:21828:9377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000453
VERSION     KCVO01000453.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21828:9377"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..414
                     /note="immunoglobulin light chain variable region"
     V_region        90..414
     V_segment       90..376
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72482.1"
                     /translation="DYYCYSMDSSGTQSVF"
     J_segment       382..414
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           90 a          140 c          120 g          102 t
ORIGIN      
        1 acatggggag gcagagctct gggtgtctca ccatggcctg gattcctctc ctactccccc
       61 tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca ccctcggtgt
      121 cagtgtcccc aggacagacg gccaggatca cctgctctgg agatgcattg ccaaaaaagt
      181 atgcttattg gttccagcag aagccaggcc agtcccctgt gctgatcatc tatgaggaca
      241 acatacggcc ctctgggatc cctgagagat tctctggctc cagctcaggg acagtggcca
      301 ccttgactat cagtggggcc cagggggagg atgaagctga ctactactgt tattcaatgg
      361 atagcagtgg tactcagagt gtcttcggtg ctgggacccg gctcaccgtc ctaggtcagc
      421 ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01000454             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:21899:10807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000454
VERSION     KCVO01000454.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21899:10807"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72483.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       391..423
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          142 c          123 g          103 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 caaaaaagta tgcttattgg ttccagcaga agccaggcca gtcccctgtg ctgatcatct
      241 atgaagacga caaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc agtggggccc aggtggagga tgaagctgac tactactgtt
      361 actcaataga tagtagtggt agtcatagcg tcttcggtgc tgggacccgg ctcaccgtcc
      421 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCVO01000455             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:14789:3482
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000455
VERSION     KCVO01000455.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14789:3482"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72484.1"
                     /translation="DYYCSSYADTYTFVF"
     J_segment       401..435
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           79 a          161 c          121 g          112 t
ORIGIN      
        1 acatgggggg gggtctcaga cggcagcgct ctcgggacat ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctcgctc agtgtctggg tctcctggac agtcggtcac catctcctgc actggcacca
      181 gcagtgacat cggtggttat aactttgtct cctggtacca acaccatcca ggcacagccc
      241 ccaaactcgt gatttatgag gtcactcagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcagcgcg gcctccctga ccatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgctcctca tatgcagaca cttacacttt tgtgttcgga agtggcacca
      421 agttgaccgt cctcggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01000456             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:19665:11704
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000456
VERSION     KCVO01000456.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19665:11704"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72485.1"
                     /translation="DYYCSSTDTSGNHVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           91 a          143 c          115 g           97 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gaaagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 ccagtggtaa tcatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000457             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:6891:16491
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000457
VERSION     KCVO01000457.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:6891:16491"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72486.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       412..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          156 c          131 g          108 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggaccccgg gcagagggtc accatctcgt
      181 gcactgggag cagctccaac attggaggtt attttgtata ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctatgaca ataataagcg accctcaggg atttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagcctg
      361 gggatgaggc tgattattac tgcggagcat gggatagcag tctgagtgct cgcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgcccccgcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01000458             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:13153:10724
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000458
VERSION     KCVO01000458.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:13153:10724"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72487.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           86 a          154 c          123 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagtactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000459             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:26950:10077
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000459
VERSION     KCVO01000459.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:26950:10077"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72488.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          160 c          125 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggctctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000460             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:13622:12323
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000460
VERSION     KCVO01000460.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13622:12323"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..429
                     /note="immunoglobulin light chain variable region"
     V_region        96..429
     V_segment       96..387
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72489.1"
                     /translation="DYFCSVWDSSLTIYIF"
     J_segment       392..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          153 c          120 g          107 t
ORIGIN      
        1 acatgggggc acaggaggca gcactcagga cagtctccag catggcctgg tctctccttc
       61 tcactctgct ggttcactgc acagggtccg gggcccagcc tgtgctgacg cagccgccct
      121 cagcatctgg ggcccccggg cagagggtca ccatctcctg cactgggagc agctccaaca
      181 tcggggcggg ttattctgta tcctggtatc agcagttccc aggaacagcc cccaaactcc
      241 tcatctatga aaataataag cgaccctcag gggtttctga ccgattctct ggctccaagt
      301 ctggtacctc agcctccctg actatcactg gactccaatc tgaggatgag gctgattatt
      361 tctgctctgt ctgggatagc agcctgacta tttacatctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01000461             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:22169:7592
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000461
VERSION     KCVO01000461.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22169:7592"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72490.1"
                     /translation="DYYCSSFASSSTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           85 a          156 c          122 g          110 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg gcctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggtacca acaacaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtaatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca ttcgcaagca gtagcacttg ggttttcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000462             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:6709:14126
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000462
VERSION     KCVO01000462.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:6709:14126"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72491.1"
                     /translation="DYYCSSRDSSGNYVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           91 a          141 c          127 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tttgcttatt ggttccaaca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac agcaagcggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaaggtg actactactg
      361 ttcctcaaga gatagcagtg gtaattatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000463             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:20825:15577
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000463
VERSION     KCVO01000463.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20825:15577"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..446
                     /note="immunoglobulin light chain variable region"
     V_region        117..446
     V_segment       117..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72492.1"
                     /translation="DYYCQSYDGSLSAVLF"
     J_segment       411..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>485
                     /gene="IGLC"
BASE COUNT           89 a          156 c          128 g          112 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaggtt attatgtgca gtggtaccat caacttccag
      241 gaacggcccc caaagttctc atctctgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggtacctcag cctccctgat catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacggcag cctgagtgcc gtgttattcg
      421 gaggagggac ccggctgacc gtcctaagtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01000464             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:15031:16967
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000464
VERSION     KCVO01000464.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15031:16967"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72493.1"
                     /translation="DYFCSSYTGSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           83 a          155 c          123 g          111 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtaatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgtt catctctggg ctcctggctg aggacgaggc
      361 tgattatttc tgcagctcat acacaggcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000465             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:18718:8825
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000465
VERSION     KCVO01000465.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18718:8825"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..392
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72494.1"
                     /translation="DYYCSSRDSSGNYVF"
     J_segment       393..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           91 a          142 c          129 g          102 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccctcctc actttctgca caggctctgc agcctcctat gagctgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg
      181 cattgccaga aaaatttgct tattggttcc aacagaagcc aggccagtcc cctgtgctga
      241 tcatcaatga ggacagcaag cggccctctg ggatccctga gagattctct ggctccagct
      301 cagggacagt ggccaccttg actctcagtg gggcccaggt ggaggatgaa ggtgactact
      361 actgttcctc aagagatagc agtggtaatt atgtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000466             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:22801:13053
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000466
VERSION     KCVO01000466.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22801:13053"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72495.1"
                     /translation="DYHCYSTDSSTNHGVF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           96 a          145 c          122 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagg tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tactcatcat
      241 ctatgaggac ttcaaacggc cccctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actaccactg
      361 ttactcaaca gatagcagta ctaatcatgg cgtattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000467             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:6996:18144
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000467
VERSION     KCVO01000467.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:6996:18144"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72496.1"
                     /translation="DYYCGAWDSSLNTRLF"
     J_segment       410..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          157 c          127 g          107 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gaccccgggc agagggtcac catctcgtgc
      181 actgggagca gctccaacat tggaggttat cttgtatact ggtaccagca gttcccagga
      241 acagccccca aactcctcat ctatgacaat aataagcgac cctcagggat ttctgaccga
      301 ttctctggct ccaagtctgg tacctcagcc tccctgacca tcactgggct ccagcctggg
      361 gatgaggctg attattactg cggagcatgg gatagcagcc tgaatactcg cttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01000468             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:8453:4805
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000468
VERSION     KCVO01000468.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8453:4805"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..422
                     /note="immunoglobulin light chain variable region"
     V_region        104..422
     V_segment       104..385
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72497.1"
                     /translation="DYYCQSTDSSGYIF"
     J_segment       386..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT          100 a          136 c          120 g          104 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgtg gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actgacaaaa aattatgctc agtggttcca gcagaagcca ggccaggccc ctgtgctgct
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cggttctcta gttccagttc
      301 agggacaaca gttaccttga ccctcagtcg ggcccaggta gaagatgagg ctgactatta
      361 ttgtcaatca acagacagca gtggttacat cttcggtgct gggacccggc tcaccgtcct
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01000469             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:9423:9707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000469
VERSION     KCVO01000469.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9423:9707"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..428
                     /note="immunoglobulin light chain variable region"
     V_region        105..428
     V_segment       105..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72498.1"
                     /translation="DYFCCSYADTYTFVF"
     J_segment       405..428
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>473
                     /gene="IGLC"
BASE COUNT           84 a          156 c          121 g          112 t
ORIGIN      
        1 acatgggggg gggtctcaga cggcagcgct ctcgggacat ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctcgctc agtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cggtggttat aactttgtct cctggtacca acaacatcca ggcacaaccc
      241 ccaaactcat gatttatgag gtcaatcagc ggccctcagg ggtctctgat cgcttctctg
      301 gctcaaagtc tggcaacacg gcctccctga ccgtctccgg ggtccaggct gaggacgagg
      361 ctgattattt ctgctgctca tatgcagaca cctacacttt tgttttcgga agtggcacca
      421 ggttgaccgt cgtcggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01000470             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:3618:10027
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000470
VERSION     KCVO01000470.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:3618:10027"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..427
                     /note="immunoglobulin light chain variable region"
     V_region        105..427
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72499.1"
                     /translation="DYYCQVWDSSSDHWVF"
     J_segment       392..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>467
                     /gene="IGLC"
BASE COUNT           86 a          148 c          140 g           93 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca caggctctgc ggtctcctat gagctgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggcccg gatcacctgt gggggagaca
      181 acattggaag taaaagtgta cagtggttcc aacagaagcc accgcaggcc cctgtgctgg
      241 tcatttatgg tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cgggaatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgggtatt cggcggaggg acccgcctga
      421 ccgtcctcgg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000471             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:21579:5837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000471
VERSION     KCVO01000471.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21579:5837"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72500.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       391..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           88 a          141 c          137 g           96 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggtct cctatgacct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtatggg agacaatgtt
      181 ggaagtgaat atgtgcactg gtaccaacag aagccaccgc aggcccctgt ggtggtcatc
      241 cattataata gtgaccggcc ctcagggatc cctgaacgat tctctggctc caaatcaggg
      301 agcgccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtagtag tgatcatagt ttattgggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000472             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:17571:9677
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000472
VERSION     KCVO01000472.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17571:9677"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72501.1"
                     /translation="DYYCYSTENSDTHRGFF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           91 a          141 c          119 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatctcct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag gcaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ttcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagaga
      361 acagtgatac tcataggggc ttcttcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000473             297 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:12650:11398
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000473
VERSION     KCVO01000473.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 297)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12650:11398"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..259
                     /note="immunoglobulin light chain variable region"
     V_region        8..259
     V_segment       8..223
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <187..>231
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72502.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       224..259
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        260..>297
                     /gene="IGLC"
BASE COUNT           60 a           90 c           78 g           69 t
ORIGIN      
        1 acatggggtg acattggtga ttataaccgt gtctcctggt accaacagca cccaggcaaa
       61 gcccccaaac ttatgattta tgaggtcagt gatcggccct caggggtctc tgatcgcttc
      121 tctggttcca agtctggcaa cacggcctcc ctgatcatct ctgggctcca ggctgaggac
      181 gaggctgatt attactgcag ctcatacaca agcagtagca cttgggtatt cggcggaggg
      241 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000474             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:5837:18814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000474
VERSION     KCVO01000474.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5837:18814"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72503.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          161 c          123 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcgatc actctcttcc
      481 cg
//
LOCUS       KCVO01000475             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:18002:2948
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000475
VERSION     KCVO01000475.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18002:2948"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..380
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72504.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       384..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           98 a          144 c          120 g           96 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcgttgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 cagaaaaata tgcttattgg taccagcaga aaccaggcca gtcccctatg ctgatcatct
      241 atgaggacaa caaacggccc tctgggatcc ctgaaagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc actggggccc aggtggagga tgaagctgac tactactgtt
      361 actcagcaga caacagtggt cagggctcat tcggaggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000476             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:10475:12079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000476
VERSION     KCVO01000476.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10475:12079"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72505.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           86 a          159 c          119 g          109 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct cactctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgac gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca ctaccacttg gctattcggc ggagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000477             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:25463:17610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000477
VERSION     KCVO01000477.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:25463:17610"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..397
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72506.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       398..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           82 a          150 c          125 g          114 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcactct caggacgtct ccaccatggc ctgggctctg
       61 ctcctcttca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 tctccctctg tgtctgggtc tcctggacag tcggtcacca tttcctgcac tggaaccagc
      181 agtgacattg gtggttttga gcgtgtctcc tggtaccaac agcacccagg caaagccccc
      241 aaactcttga tttatgaggt cagttatcgg ccctcagggg tctctgatcg cttctctggt
      301 tccaagtctg gcaacacggc ctccctgatc atctctgggc tccaggctga ggacgaggct
      361 gattattatt gcagctcata cgcaagtagt agtacttggg tattcggcgg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000478             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:15687:12480
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000478
VERSION     KCVO01000478.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15687:12480"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72507.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          152 c          125 g          112 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttttg agcgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcttg atttatgagg tcagttatcg gcccgcaggg gtctctgatc gcttctctgg
      301 ttccaagtct gccaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattat tgcagctcat acacaagtag tagtacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000479             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:17319:6812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000479
VERSION     KCVO01000479.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17319:6812"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72508.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       378..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           88 a          138 c          117 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagtcaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gggagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggtgcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gtagtggtaa ttatgttttc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000480             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:13099:11740
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000480
VERSION     KCVO01000480.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13099:11740"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72509.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       389..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           89 a          140 c          138 g           95 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctta ctgcacaggg tctgcggtct cctatgagct cactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg aggcaatgtt
      181 ggaagtgaat atgtccactg gtatcaacag aagccaccgc aggcccctat ggtggtcatc
      241 tattataata gtgaccggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggagtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtaggag tgatcatagc ttattgggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000481             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:13910:14066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000481
VERSION     KCVO01000481.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13910:14066"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..453
                     /note="immunoglobulin light chain variable region"
     V_region        120..453
     V_segment       120..413
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72510.1"
                     /translation="YYYCLSYDSSLSAHYIF"
     J_segment       416..453
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           96 a          166 c          119 g          110 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctc gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacacagcca ccctcagtgt ctggggcccc agggcagagg gtcaccatct
      181 cgtgcactgg gagcagctcc agcattggag gtgattatgt atcctggtac caacagctcc
      241 caggaacgac ccccaaactc ctcatctatc aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtacct cagcctccct gaccatcact gggctccaga
      361 ctgaggatga ggcttattac tactgcctgt cctatgacag cagcctgagt gctcattaca
      421 tcttcggtcc tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca
      481 ctctgttccc g
//
LOCUS       KCVO01000482             295 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:5455:11019
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000482
VERSION     KCVO01000482.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 295)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5455:11019"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..257
                     /note="immunoglobulin light chain variable region"
     V_region        8..257
     V_segment       8..222
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>229
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72511.1"
                     /translation="DYYCFVYYSGTQFF"
     J_segment       227..257
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        258..>295
                     /gene="IGLC"
BASE COUNT           67 a           92 c           76 g           60 t
ORIGIN      
        1 acatggggga gcagtcacca gtggtaactt tccaaactgg ttccagcaga aacctggaca
       61 agtccccagg ggactgattt acaatacaaa caacaaacac tcctggaccc ctgcccggtt
      121 ctcaggctcc ctcgctgggg gcaaagctgc cctgacactg tcaggagcac agcccgagga
      181 cgaggctgat tattactgct tcgtgtacta tagtggtact caattcttcg gaggagggac
      241 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000483             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:21920:13097
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000483
VERSION     KCVO01000483.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:21920:13097"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72512.1"
                     /translation="DYYCQSADDSYNYIF"
     J_segment       398..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          159 c          122 g          106 t
ORIGIN      
        1 acatgggggt gactcagaaa gcagagcctg gggcgtctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt tcactcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc gcagcagtgg
      181 cagcattgac agtgaatatg tgcggtgtta ccagcagcgc ccgggcaatg cccccaccac
      241 agtgatttac aaagataacc aaagaccctc tggggtccct gatcggttct ctggctccat
      301 tgacagctcc tccaactctg cctccctcgc catctctggg ctgaagtctg aggacgaggc
      361 tgactactac tgtcagtctg ctgatgacag ctacaattac atcttcggtg ctgggtcccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01000484             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:14709:13643
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000484
VERSION     KCVO01000484.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14709:13643"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..389
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72513.1"
                     /translation="DYYCSAWDNSLSGYIF"
     J_segment       391..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          148 c          125 g          107 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctctcct
       61 tctcactctg ctggttcact gcacagggtc ctgggcccag tctgtgctga cgcagccgcc
      121 ctcagcatct ggggcccccg ggcagagggt caccatctcg tgcactggga gcagctccaa
      181 cattggaggt tattctgtat cctggtaccg gcaacgccca ggagcggtcc ccaaactcct
      241 catctttgaa aataataagc gaccctcagg tgtctctgac cgattctctg gctccaagtc
      301 tggtgtctca gcctccctat gcatcactgg actccagtct gaggatgagg ctgattatta
      361 ctgctcagct tgggataaca gcctgagtgg ttacatcttc ggtgctggga cccgagtcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCVO01000485             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:17270:19574
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000485
VERSION     KCVO01000485.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:17270:19574"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..386
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72514.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       390..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           87 a          141 c          137 g           96 t
ORIGIN      
        1 acatgggggc ctcgggaagc agccttggcg gtgcctcagc catggccggg acccttctcc
       61 tcctcggcct ccttgcttac tgcacaggct ctgcggtctc ctatgacctg actcagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgtgtggga gacaatgttg
      181 gaagtgaata tgtgcactgg taccaacaga agccaccgca ggcccctgtg gtggtcatcc
      241 attataatag tgaccggccc tcagggatcc ctgaacgatt ctctggctcc aaatcaggga
      301 gcgccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga cagtagtagt gatcatagtt tattgggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000486             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:9721:13923
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000486
VERSION     KCVO01000486.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9721:13923"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72515.1"
                     /translation="DYHCQVWDSSSDVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           85 a          144 c          140 g           95 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctccttt gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gtattggaag tagaagcgtg cagtggtacc agcagaagcc accgcaggcc cttgcactgg
      241 tcatctatgc tgatagcgaa cggccctcag ggatccctga gcgcttctct ggctccaatc
      301 tagggaacac cgccaccctg accattagcg gcgtcgaggc cggggatgag gctgactatc
      361 actgtcaggt gtgggacagt agtagtgatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000487             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:9220:10474
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000487
VERSION     KCVO01000487.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9220:10474"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72516.1"
                     /translation="DYYCQVWDSSSDHIFF"
     J_segment       396..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          146 c          134 g           98 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgag ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaacc
      181 ttggagataa atatctacac tggtaccagc agaagccacc gcgggcccct gttctggtca
      241 tctactatga tagtgaccgg ccctcatgga tccctgagcg attctctggg tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatcata tctttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000488             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:25344:5241
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000488
VERSION     KCVO01000488.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:25344:5241"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72517.1"
                     /translation="EYHCFSTDSSGNHRGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          143 c          126 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgacgac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcattggggc ccaggtggag gatgaagctg agtaccactg
      361 tttctcaaca gatagtagtg gtaatcatag gggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000489             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:10537:17667
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000489
VERSION     KCVO01000489.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10537:17667"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72518.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       393..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          141 c          125 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaagac gacaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaaggtg actactactg
      361 ttactcaata gacagtagtg gtagtcatag cgtcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000490             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:17348:21641
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000490
VERSION     KCVO01000490.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17348:21641"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72519.1"
                     /translation="DYYCYSIDINDNESIF"
     J_segment       381..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           93 a          137 c          114 g          105 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acaaccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagtg
      241 agcggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctattgttac tcaatagata
      361 tcaatgataa tgagagcatt ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000491             408 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:10484:13419
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000491
VERSION     KCVO01000491.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 408)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 408)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10484:13419"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..408
                     /note="immunoglobulin light chain variable region"
     V_region        105..408
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72520.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       389..408
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
BASE COUNT           81 a          115 c          127 g           85 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcattggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttgtactgg
      241 tcatctatgc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttattcgg aggaggga
//
LOCUS       KCVO01000492             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:11153:8611
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000492
VERSION     KCVO01000492.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11153:8611"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..404
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72521.1"
                     /translation="DYYCQSYDSSLSAVFF"
     J_segment       406..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           90 a          156 c          125 g          109 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagcacct ccaatattgg agattattat gtgcagtggt accagcagct tccaggaacg
      241 gcccccagac tcctcatcta tgaaaataat aaacgaccct cagggatttc tgatcgattc
      301 tctggctccc agtctggtac ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgcca gtcctatgac agcagcctga gtgccgtgtt tttcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000493             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:19841:15104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000493
VERSION     KCVO01000493.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19841:15104"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72522.1"
                     /translation="DYYCQVWDSRTKYIF"
     J_segment       392..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          152 c          133 g           91 t
ORIGIN      
        1 acatgggggc ctgactttgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactgcac aggctctgcg gcctcctatg acctgactca
      121 gccaccctcg gtgtcggtgc ccccaggaca gacagccagg atcacctgtg ggggagacac
      181 cattggaagt agaagtgtgc actggtacca gcagaagcca ccgcaggccc ctgccctggt
      241 catatatact gatagcgagc ggccctcagg gatccctgac cgattctctg gctccaattc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ttgtcaggtg tgggacagta ggactaaata catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000494             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:19005:11595
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000494
VERSION     KCVO01000494.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19005:11595"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72523.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       397..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           93 a          143 c          126 g          105 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccctcctc actttctgca caggctctgc agcctcctat gagctgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg
      181 cattgccaaa aaagtatgct tattggttcc agcagaagcc aggccagtcc cctgtgctga
      241 tcatctatga agacgacaaa cggccctctg ggatccctga gagattctct ggctccagct
      301 cagggacagt ggccaccttg actatcagtg gggcccaggt ggaggatgaa gctgactact
      361 actgttactc aatagatagt agtggtagtc atagcgtctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01000495             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:19915:18719
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000495
VERSION     KCVO01000495.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19915:18719"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72524.1"
                     /translation="DYFCYSTTSSGNHRLF"
     J_segment       395..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           96 a          140 c          127 g          104 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccctcctc actttctgca caggctctgc agcctcctat gagctgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg
      181 cattgccaaa aaaatatgtt tattggttcc agcagaagac aggccagtcc cctgtgctga
      241 tcatctatga ggacagcaaa cggccctctg ggatccctga gagattctct ggctccagct
      301 cagggacagt ggccaccttg actatcagtg gggcccaggt ggaagatgaa gctgactact
      361 tctgttactc aacgactagc agtggtaatc ataggttatt cggaggaggg acccgggtga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000496             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:17729:17609
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000496
VERSION     KCVO01000496.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17729:17609"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72525.1"
                     /translation="DYYCQVWDITTDHDVF"
     J_segment       389..425
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           96 a          137 c          127 g          103 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatgacct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ttctgcggcc tcctatgagc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaaa aatgtccact ggtaccaaca gaagccaccg caggcccctg tattggtcat
      241 ctattatgat atcgaacggc cctcagggat ccctgagcga ttctctggcg ccaaatcagg
      301 gaacaccgcc accctgatca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattacta ctgatcatga tgtgtttgga agtggcacca aattgaccgt
      421 cctcggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01000497             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:10099:10596
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000497
VERSION     KCVO01000497.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10099:10596"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72526.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          161 c          125 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000498             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:15434:11606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000498
VERSION     KCVO01000498.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:15434:11606"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    154..306
                     /note="immunoglobulin light chain variable region"
     V_region        154..306
     V_segment       154..269
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72527.1"
                     /translation="DYYCYSTRSSGYHGLF"
     J_segment       270..306
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           62 a          113 c           90 g           79 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctgagag attctctggc tccagctcag
      181 ggacagtggc caccttgact atcagtgggg cccaggtgca ggatgaagct gactactact
      241 gttactcaac tcgtagcagt ggttatcatg gcttattcgg aggagggacc tggctgaccg
      301 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000499             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:14192:20002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000499
VERSION     KCVO01000499.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14192:20002"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..407
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72528.1"
                     /translation="DYYCSAWDNSLSGYIF"
     J_segment       409..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           89 a          153 c          129 g          113 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctctccttc tcactctgct ggttcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagcatctgg ggcccccggg cagagggtca ccatctcgtg
      181 cactgggagc agctccaaca ttggaggtta ttctgtatcc tggtaccggc aacgcccagg
      241 agcggtcccc aaactcctca tctttgaaaa taataagcga ccctcaggtg tctctgaccg
      301 attctctggc tccaagtctg gtgtctcagc ctccctatgc atcactggac tccagtctga
      361 ggatgaggct gattattact gctcagcttg ggataacagc ctgagtggtt acatcttcgg
      421 tgctgggacc cgagtcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCVO01000500             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:19651:8236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000500
VERSION     KCVO01000500.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19651:8236"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72529.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          143 c          138 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctcactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggaggca
      181 atgttggaag tgaatatgtc cactggtatc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatctatta taatactgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt ttgggacagt aggagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000501             353 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:9521:15598
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000501
VERSION     KCVO01000501.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 353)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 353)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9521:15598"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..315
                     /note="immunoglobulin light chain variable region"
     V_region        116..315
     V_segment       116..278
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <240..>287
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72530.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       280..315
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        316..>353
                     /gene="IGLC"
BASE COUNT           69 a          104 c          102 g           78 t
ORIGIN      
        1 acatggggga gagtatgaag aggggcaggg agagatttgg ggaagctctg cttcagctgt
       61 gggcacagga ggcagcactc aggacagtct ccagcatggc ctggtctcct ctcctcctca
      121 ccctcctcat ctatgacaat aataagcgac cctcagggat ttctgaccga ttctctggct
      181 ccaagtctgg tacctcagcc tccctgacca tcactgggct ccagcctggg gatgaggctg
      241 attattattg cggagcatgg gatagcagcc tgagtgctcg cttattcgga ggagggaccc
      301 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000502             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:6257:9671
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000502
VERSION     KCVO01000502.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:6257:9671"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72531.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       401..435
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           82 a          159 c          122 g          110 t
ORIGIN      
        1 acatgggggg gggtctcaga cggcagcgct ctcgggacat ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctcgctc agtgtctggg tctcctggcc agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cgggacttac aactatgtct cctggtacca acagcatcca ggcacagccc
      241 ccaaactcac gatttttgag gtcagtgagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgttgctca tatgcagaca cctacacttt tgtgtttgga ggtggcacca
      421 gattgaccgt cctcggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01000503             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:19574:4788
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000503
VERSION     KCVO01000503.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19574:4788"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72532.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       391..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          142 c          127 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagt tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcagacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccagggggag gatgaagctg actactactg
      361 ttattcaatg gatagcagtg gtactcagag catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000504             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:25312:12789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000504
VERSION     KCVO01000504.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25312:12789"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..399
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72533.1"
                     /translation="DYHCMIRHNNAYIF"
     J_segment       400..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           92 a          157 c          113 g          111 t
ORIGIN      
        1 acatgggggc ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcgc agcctgtgct gactcagcca acctccctct
      121 cagcatctcc tggaacatca gccagactca cctgcacctt gcgcagtggc atcagtgttg
      181 gtagttacgg gattttctgg taccaacaga agccagggag tcctccccgg tatcttctga
      241 actaccacac agactcagag aagcaccagg gatctggagt ccccagccgc ttctctggat
      301 ccaaggatac ttcggccaat gcaggctttt tactcatctc tgggctccag tctgaggatg
      361 aggctgacta tcactgtatg attcggcaca acaatgctta catcttcggt gctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000505             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:12221:16848
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000505
VERSION     KCVO01000505.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12221:16848"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72534.1"
                     /translation="DYYCQVWDSSSKNMIF"
     J_segment       395..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          151 c          132 g           89 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctttga gctgactcag
      121 ccaccctcgg tgtcagcggc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaactt acaatgtgca ctggtaccag cagaagccac cccaggcccc tgtgctggtc
      241 atctatgctg ataccaagcg gccctcaggg atccctgagc gattctctgg ctccaattca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactactac
      361 tgtcaggtgt gggacagtag tagtaaaaac atgatattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000506             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:21520:9292
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000506
VERSION     KCVO01000506.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:21520:9292"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72535.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           84 a          152 c          123 g          113 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttttg agcgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcttg atttatgagg tcagttatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct gccaacacga cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattat tgcagctcat acacaagtag tagtacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000507             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:14085:23079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000507
VERSION     KCVO01000507.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14085:23079"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72536.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          163 c          119 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc ctttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa caccacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacccgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac ttccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000508             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:10613:15342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000508
VERSION     KCVO01000508.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10613:15342"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72537.1"
                     /translation="DYYCSSYADTYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           79 a          161 c          120 g          112 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggcaccag
      181 cagtgacatc ggtggttata actttgtctc ctggtaccaa caccatccag gcacagcccc
      241 caaactcgtg atttatgagg tcactcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcagcgcgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgctcctcat atgcagacac ttacactttt gtgttcggaa gtggcaccaa
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01000509             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:20437:13611
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000509
VERSION     KCVO01000509.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20437:13611"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..398
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72538.1"
                     /translation="EYYCSSYVGTKTYWVF"
     J_segment       400..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          155 c          126 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcggcactc tcgggacatc tccaccatgg cctgggatct
       61 gctcctcttc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctca atgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttata gccgtgtctc ctggtaccaa cagcacccag acaaagtccc
      241 caaactcatg atttatgagg tcagtcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgaatattac tgcagctcat atgtaggcac caagacttat tgggtattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000510             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:9639:13337
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000510
VERSION     KCVO01000510.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:9639:13337"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72539.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          160 c          125 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggaaga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000511             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:12534:9988
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000511
VERSION     KCVO01000511.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12534:9988"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72540.1"
                     /translation="DYYCYSTRTSGYHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          142 c          123 g          106 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ctctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtgcag gatgaagctg actactactg
      361 ttactcaact cgtactagtg gttatcatgg cttattcgga ggagggacct ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000512             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:10734:9375
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000512
VERSION     KCVO01000512.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:10734:9375"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    42..366
                     /note="immunoglobulin light chain variable region"
     V_region        42..366
     V_segment       42..329
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <291..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72541.1"
                     /translation="DYYCQVWDSRSDHNLL"
     J_segment       333..366
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>404
                     /gene="IGLC"
BASE COUNT           83 a          118 c          117 g           86 t
ORIGIN      
        1 acatgggcgg cctccttgct tactgcacag gctctgcggt ctcctatgag ctcactcagc
       61 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggaggcaatg
      121 ttggaagtga atatgtccac tggtatcaac agaagccacc gcaggcccct gtcgtggtca
      181 tctattataa tactgaccgg ccctcaggga tccctgagcg attctctgga ttcaaatcag
      241 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      301 gtcaggtgtg ggacagtagg agtgatcata atttattggg aggagggacc cggctgaccg
      361 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000513             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:20394:9484
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000513
VERSION     KCVO01000513.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20394:9484"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..450
                     /note="immunoglobulin light chain variable region"
     V_region        117..450
     V_segment       117..410
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72542.1"
                     /translation="DYYCSLWDSRLSSRLF"
     J_segment       418..450
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           94 a          156 c          128 g          110 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctctcctt ctcactctgc tggttcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagcatctg gggcccccgg gcagagggtc accatctcct
      181 gcactgggac cagctccaac atcggggcga attattatgt ttcctggtac cagcagttcc
      241 caggaacagc ccccaaactc ctcatctatg aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtacct cagcctccct gaccatctct ggactccaat
      361 ctgaggatga ggctgattat tactgctcac tatgggatag caggctgagt agtcggttat
      421 tcggcggagg gacccgactg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCVO01000514             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:8620:2870
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000514
VERSION     KCVO01000514.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8620:2870"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72543.1"
                     /translation="DYYCQVWDSSSDVFF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          141 c          140 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcattggaag tagaagtgtg cagtggtatc agcagaagcc accgcaggcc cttgtactgg
      241 tcatctatgc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttcttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000515             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:15844:12416
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000515
VERSION     KCVO01000515.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15844:12416"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..215
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72544.1"
                     /translation="DYYCQSHDSSLSVLF"
     J_segment       216..251
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           58 a           87 c           74 g           70 t
ORIGIN      
        1 acatgggatt ggaggttatt atgtatactg gtatcagcag ctcccaggaa tggcccccag
       61 actcctcatc tttgacaatg ataagcgacc ctcaggggtt tctgaccgat tctctggctc
      121 caagtctggt acctcagcct ccctgaccat cactgggctc cagactgagg atgaggctga
      181 ttattactgc cagtcccatg acagcagcct gagtgtgtta ttcggaggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000516             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:14407:10707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000516
VERSION     KCVO01000516.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14407:10707"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..422
                     /note="immunoglobulin light chain variable region"
     V_region        100..422
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72545.1"
                     /translation="DYYCQVWDFSGDHNIF"
     J_segment       389..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>462
                     /gene="IGLC"
BASE COUNT           90 a          148 c          127 g           97 t
ORIGIN      
        1 acatgggggg cctcaggagg cagcattgac ggtgcctcag ccatgacctg gacttttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggcct cctctgaact gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccagaatca cctgtgggag agacaacatt
      181 ggaaataaaa atgtgcactg gtaccagcag cggccaccgc gggcccctgt actggtcatc
      241 tattatgata ccgagcggcc ctcagggatc cctgagcgat tctctggctc cacatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg actttagtgg tgatcataac atcttcgatg ctgggacccg gctcaccgtc
      421 ctcggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01000517             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:19356:17477
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000517
VERSION     KCVO01000517.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19356:17477"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72546.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       394..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           94 a          145 c          127 g          102 t
ORIGIN      
        1 acatgggggg gctgtgggct caggaggcag agctctgggt gtctcaccat ggcctggatt
       61 cctctcctac tccccctcct cactttctgc acaggctctg cagcctcctc tgagctgaca
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg ctctggagat
      181 gcattgtcaa aatactatgc ttattggttc cagcagaagc caggccagtc ccctgtggcg
      241 atcatctatg aggacaacaa acggccctct gggatccctg agagaatctc tggctccagc
      301 tcagggacag tggccacctt gactatcagt ggggcccagg tcgaggatga agctgactac
      361 tactgttact caacagatag cagtggtact aatggcttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000518             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:7619:7265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000518
VERSION     KCVO01000518.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7619:7265"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..397
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72547.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       398..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           88 a          155 c          121 g          107 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcactct caggacgtct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 tctccctctg tgtctgggtc tcctggacag tcggtcacca tttcctgcac tggaaccagc
      181 agtgacattg gtgattataa ccgtgtctcc tggtaccaac aacacccagg caaagccccc
      241 aaactcatga tttatgaggt cagtgatcgg ccctcagggg tctctgatcg cttctctggt
      301 tccaagtctg gcaacacggc ctccctgatc atctctgggc tccaggctga ggacgaggct
      361 gattattact gcagctcata cacaagcagt agcacttggg tattcggcgg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000519             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:27312:5961
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000519
VERSION     KCVO01000519.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:27312:5961"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..432
                     /note="immunoglobulin light chain variable region"
     V_region        99..432
     V_segment       99..392
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72548.1"
                     /translation="DYYCSLWDSRLSSRVF"
     J_segment       397..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           91 a          150 c          125 g          104 t
ORIGIN      
        1 acatgggggg ggcacaggag gcagcactca ggacagtctc cagcatggcc tggtctctcc
       61 ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg acgcagccgc
      121 cctcagcatc tggggccccc gggcagaggg tcaccatctc ctgcactggg accagctcca
      181 acatcggggc gaattattat gtttcctggt accagcagtt cccaggaaca gcccccaaac
      241 tcctcatcta tgaaaataat aagcgaccct caggggtttc tgaccgattc tctggctcca
      301 agtctggtac ctcagcctcc ctgaccatct ctggactcca atctgaggat gaggctgatt
      361 attattgctc actatgggat agcaggctga gtagtcgggt attcggcgga gggacccgac
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000520             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:9295:11360
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000520
VERSION     KCVO01000520.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9295:11360"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..384
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72549.1"
                     /translation="DYYCYSIDSSGNRSFF"
     J_segment       388..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           98 a          140 c          121 g          102 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 caaaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgtg ctgatcatct
      241 atgaggacaa caaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgacaatc agtggggccc agatggagga tgaaactgac tactactgtt
      361 attcaataga tagtagtggt aatcgtagct tcttcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000521             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:10977:2423
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000521
VERSION     KCVO01000521.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:10977:2423"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72550.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           97 a          144 c          122 g           97 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggtaccagca gaaaccaggc cagtccccta tgctgatcat
      241 ctgtgaggac agcaaacggc cctctgggat ccctgaaaga ttctctggct ccagctcagg
      301 gacagtagcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacaacagtg gtcagggctc attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000522             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:9116:4571
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000522
VERSION     KCVO01000522.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9116:4571"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..422
                     /note="immunoglobulin light chain variable region"
     V_region        102..422
     V_segment       102..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72551.1"
                     /translation="DYYCYSGDSSGDGFF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           90 a          139 c          131 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc gcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaat tatgcgtatt ggtaccagca gaaaccaggc cagtcccctg tgttgatcat
      241 ctctgacgac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcggg
      301 gacagtggcc accttgacta tcaggggggc ccaggtggag gatgaaggtg actactactg
      361 ttattcagga gacagcagtg gtgatggctt tttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000523             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:19841:8895
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000523
VERSION     KCVO01000523.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19841:8895"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72552.1"
                     /translation="DYYCYSTDSSGNHRIF"
     J_segment       379..411
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           90 a          140 c          119 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc gggatcacct gctctggaga tgcattgcca caaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaggacacca
      241 agcggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccgg gtggaggatg aagctgacta ctactgttac tcaacagata
      361 gtagtggtaa tcataggata ttcggcggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000524             290 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:27951:7295
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000524
VERSION     KCVO01000524.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 290)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:27951:7295"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..252
                     /note="immunoglobulin light chain variable region"
     V_region        8..252
     V_segment       8..218
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <180..>224
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72553.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       219..252
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        253..>290
                     /gene="IGLC"
BASE COUNT           64 a           82 c           80 g           64 t
ORIGIN      
        1 acatgggatt gccagaaaaa tatgcttatt ggttccagca caagccaggc cagtcccctg
       61 tgctgatcat caatgaggac agcaaacggc cctctgggat ccctgggaga ttctctggct
      121 ccagctcagg gacagtggcc acattgactc tcagtggggc ccaggtggag gatgaagctg
      181 actactactg ttcctcaaca gatagtagtg gtaattatgt attcggcgga gggacccggc
      241 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000525             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:23955:11926
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000525
VERSION     KCVO01000525.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:23955:11926"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72554.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           82 a          151 c          126 g          114 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggtttt gagcgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactctt gatttatgag gtcagttatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ttgcagctca tacgcaagta gtagtacttg ggtattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000526             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:21932:9233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000526
VERSION     KCVO01000526.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21932:9233"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72555.1"
                     /translation="DYYCYSTRSSGYHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          141 c          123 g          106 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tactgatcat
      241 ctatgaggac agcaaacggc cctctgggat ctctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtgcag gatgaagctg actactactg
      361 ttattcaact cgtagcagtg gttatcatgg cttattcgga ggagggacct ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000527             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:14552:9191
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000527
VERSION     KCVO01000527.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:14552:9191"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72556.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       397..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          142 c          140 g           95 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagactctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaaacc agcgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga gcgattcgct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgtgtatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000528             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:20788:10120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000528
VERSION     KCVO01000528.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20788:10120"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72557.1"
                     /translation="DYYCQVWDSSSAVLF"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          141 c          136 g          100 t
ORIGIN      
        1 acatgggggg cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagattctgt ggtctcctat gagttgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggataca
      181 tcattggaag tcaaagtgtg cagtggtacc agcagaagcc accgcaggcc cttgtgctgg
      241 tcatctatgc tgataacaaa cggccctcag ggatccctga acgattctct ggctccaatt
      301 tagggatcac cgccaccctg accatcagcg gagtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgctg tattattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000529             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:13324:2744
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000529
VERSION     KCVO01000529.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13324:2744"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72558.1"
                     /translation="DYYCYSTRSSGYQGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          142 c          124 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ctctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtgcag gatgaagctg actactactg
      361 ttactcaact cgtagcagtg gttatcaagg cttattcgga ggagggacct ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000530             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:8695:11199
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000530
VERSION     KCVO01000530.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:8695:11199"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72559.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       398..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           90 a          142 c          140 g           96 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acagactctg cggtctccta tgacctgact
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 aatgttggaa gtgaatatgt gcactggtac caacagaaac cagcgcaggc ccctgtggtg
      241 gtcatccatt ataatagtga ccggccctca gggatccctg agcgattctc tggctccaaa
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag tagtagtgat cattgtgtat tgggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000531             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:19929:14923
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000531
VERSION     KCVO01000531.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19929:14923"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72560.1"
                     /translation="DYYCCSYAGRFTFVF"
     J_segment       407..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           81 a          158 c          123 g          113 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactgggac
      181 cagcagtgac atcggtggtt atgactttgt ctcctggtac caacagcttc caggcacagc
      241 ccccaaactc atgatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tccggcaaca cggcctccct gaccatctct gggctccaga ctgaggacga
      361 cgctgattat tactgctgct catatgcagg caggttcact tttgtattcg gaagtggcac
      421 caagttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01000532             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:20178:10197
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000532
VERSION     KCVO01000532.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20178:10197"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..372
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72561.1"
                     /translation="DYYCYATDSSGYRGLF"
     J_segment       374..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           88 a          138 c          123 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctgggga tgcattgccg aaaaattatg
      181 cttattggtt ccggcagaag ccaggccagt cccctgtgat gatcatctat gaggacagca
      241 aacggccgtc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac gcaacagata
      361 gcagtggtta tcgtggctta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000533             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:22342:6296
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000533
VERSION     KCVO01000533.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:22342:6296"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72562.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          143 c          137 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaactgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcattggaat tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttctactgg
      241 tcatctatgc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg ttttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000534             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:11444:15722
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000534
VERSION     KCVO01000534.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:11444:15722"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72563.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          159 c          120 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccgtcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000535             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:17126:12483
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000535
VERSION     KCVO01000535.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:17126:12483"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..392
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72564.1"
                     /translation="DYYCFVYYSGTQYF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT          100 a          153 c          115 g           97 t
ORIGIN      
        1 acatgggggg agccagagat cccttccaat accagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtggctc cagcactgga
      181 gcagtcacca gtggtaactt tccaaactgg ttccagcaga aacctggaca agtccccagg
      241 ggactgattt acaatacaaa caacaaacac tcctggaccc ctgcccggtt ctcaggctcc
      301 ctcgctgggg gcaaagctgc cctgacactg tcaggagcac agcccgagga cgaggctgat
      361 tattactgct tcgtgtacta tagtggtact caatacttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000536             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:24556:19923
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000536
VERSION     KCVO01000536.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:24556:19923"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..397
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72565.1"
                     /translation="DYYCSSYASSSTWIF"
     J_segment       398..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           88 a          156 c          121 g          106 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcactct caggacgtct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 tctccctctg tgtctgggtc tcctggacag tcggtcacca tttcctgcac tggaaccagc
      181 agtgacattg gtgattataa ccgtgtctcc tggtaccaac agcacccagg caaagccccc
      241 aaactcataa tttatgaggt cagtgatcgg ccctcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgatc atctctgggc tccaggctga ggacgaggct
      361 gattattact gcagctcata cgcaagcagt agcacttgga tattcggcgg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000537             419 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:26077:13784
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000537
VERSION     KCVO01000537.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 419)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:26077:13784"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    54..381
                     /note="immunoglobulin light chain variable region"
     V_region        54..381
     V_segment       54..346
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <312..>353
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72566.1"
                     /translation="DYYCFVYYSGTQFF"
     J_segment       351..381
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        382..>419
                     /gene="IGLC"
BASE COUNT           88 a          136 c          105 g           90 t
ORIGIN      
        1 acatgggggt cctcctccag ttcctcctca cttgctgccc agggtccaat tctcaggctg
       61 tagtgactca ggagccctca atgactgtgt ccccaggagg gacagtcact ctcacctgtg
      121 gctccagcac tggagcagtc accagtggta actttccaaa ctggttccag cagaaacctg
      181 gacaagtccc caggggactg atttacaata caaacaacaa acactcctgg acccctgccc
      241 ggttctcagg ctccctcgct gggggcaaag ctgccctgac actgtcagga gcacagcccg
      301 aggacgaggc tgattattac tgcttcgtgt actatagtgg tactcaattc ttcggaggag
      361 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000538             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:21704:4770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000538
VERSION     KCVO01000538.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21704:4770"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    57..387
                     /note="immunoglobulin light chain variable region"
     V_region        57..387
     V_segment       57..351
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <315..>359
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72567.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       352..387
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        388..>425
                     /gene="IGLC"
BASE COUNT           74 a          147 c          104 g          100 t
ORIGIN      
        1 acatgggggc tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg
       61 ctgccctgac tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accctttcct
      121 gcactggaac cagcagtgac attggtggtt ataaccgtgt ctcctggtac caacaccacc
      181 caggcaaagc ccccaaactc atgatttatg acgtcagtga tcggccctca ggggtctctg
      241 atcgcttctc tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg
      301 ctgaggacga ggctgattat tactgcagct catacgcaag cacttccact tggctattcg
      361 gcggagggac ccgcctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      421 tcccg
//
LOCUS       KCVO01000539             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:28228:9763
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000539
VERSION     KCVO01000539.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:28228:9763"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..368
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72568.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           95 a          141 c          114 g           96 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggta ccagcagaaa ccaggccagt cccctatgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gaaagattct ctggctccag ttcagggaca gtggccacct
      301 tgactatcac tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 acagtggtca gggctcattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000540             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:18377:16165
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000540
VERSION     KCVO01000540.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18377:16165"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72569.1"
                     /translation="DYYCGAWDSSLSGRLF"
     J_segment       412..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          156 c          131 g          108 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggaccccgg gcagagggtc accatctcgt
      181 gcactgggag cagctccaac attggaggtt attttgtata ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctatgaca ataataagcg accctcaggg atttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagcctg
      361 gggatgaggc tgattattac tgcggagcat gggatagcag cctgagtggt cgcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01000541             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:20158:6507
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000541
VERSION     KCVO01000541.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20158:6507"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72570.1"
                     /translation="DYYCYSTISSGNDRIF"
     J_segment       378..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           93 a          138 c          115 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 tttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacaatta
      361 gtagtggtaa tgataggatc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000542             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:14849:14362
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000542
VERSION     KCVO01000542.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14849:14362"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72571.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       391..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          142 c          126 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca aaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcagacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccagggggag gatgaagctg actactactg
      361 ttattcaatg gatagtagtg gtactcagag catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000543             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:18047:7908
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000543
VERSION     KCVO01000543.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18047:7908"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72572.1"
                     /translation="DYYCAAWDDSLSSPLF"
     J_segment       409..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           91 a          154 c          122 g          114 t
ORIGIN      
        1 acatggggac cttcagctgc gggtacagaa ggcaggactc aggataatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag ccaccctcaa cgtctggggc tcccgggcag agtgtcacca tctcttgctc
      181 tggaagcagt ttcaacattg gaagtaatta tgtaaactgg taccagcagc tcccaggaac
      241 ggcccccaaa ctcctcatct attttagtaa tcagcggccc tcaggggtcc ctgaccgatt
      301 ctctggctct aagtctggct cctcagcctc cctggccatc actggtctcc gatctgagga
      361 tgaggctgat tattactgtg cagcatggga tgatagtctg agcagtccct tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01000544             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:4685:7509
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000544
VERSION     KCVO01000544.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:4685:7509"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72573.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           91 a          141 c          118 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatctcct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag gcaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ttcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagata
      361 acagtgatac tcataggggc ttcttcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000545             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:21072:7995
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000545
VERSION     KCVO01000545.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21072:7995"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72574.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       410..446
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           95 a          160 c          122 g          107 t
ORIGIN      
        1 acatgggggg cagcttcagc tgtgggtaca gaaggcagga ctcaggacaa tctccagcat
       61 ggcctggttc cctctcctcc tcaccctcct cactcactgt gcagggtcct gggcccagtc
      121 tgtgctgact cagcctccct cagcgtctga ggccgccagg aagagtgtca ccatctcctg
      181 ttctggaagc acctccaaca tcggaactaa tagtgtatcc tggtaccagc agctcccaga
      241 aacggctccc aaactcctca tctattataa tgatcgacga gcctcaggtg tctctgaccg
      301 attctctggc tccaagtctg gcacgtcagc ctccctggcc atcagtgggc tccagaccga
      361 ggatgaggct gattattact gcgcagcatg ggataacagc ctgagcggtt acatcttcgg
      421 tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      481 cccg
//
LOCUS       KCVO01000546             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:12833:14198
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000546
VERSION     KCVO01000546.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12833:14198"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..381
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72575.1"
                     /translation="DYHCQVWDSSSDVLF"
     J_segment       384..421
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           87 a          141 c          138 g           93 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctgcacagac tctgtggtct cctatgaatt gactcagcca
      121 cgctcagtgt ccgtgtcccc aggacagacg gccaggatca cctgtggggg agacagtatt
      181 ggaagtagaa gcgtacagtg gtaccagcag aagccaccgc aggcccttgc actggtcatc
      241 tatgctgata gcgaacggcc ctcagggatc cctgagcgat tctctggctc caatctaggg
      301 aacaccgcca ccctgaccat tagcggcgtc gaggccgggg atgaggctga ctatcactgt
      361 caggtgtggg acagtagtag tgatgtgtta ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000547             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:16027:18086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000547
VERSION     KCVO01000547.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:16027:18086"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72576.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       391..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          143 c          125 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca aaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac aacagacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc gccttgacta tcagtggggc ccagggggaa gatgaagctg actactactg
      361 ttattcaatg gatagcagtg gtactcagag catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000548             495 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:21667:18267
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000548
VERSION     KCVO01000548.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 495)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:21667:18267"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..457
                     /note="immunoglobulin light chain variable region"
     V_region        124..457
     V_segment       124..417
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>429
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72577.1"
                     /translation="DYYCLSYDSSLSAHYIF"
     J_segment       420..457
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        458..>495
                     /gene="IGLC"
BASE COUNT           96 a          166 c          123 g          110 t
ORIGIN      
        1 acatgggggg gggaagctct gcttcagctg tgggcacagg aggcagcact caggacagtc
       61 tccagcatgg cctcgtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg
      121 gcccagtctg tgctgacaca gccaccctca gtgtctgggg ccccagggca gagggtcacc
      181 atctcgtgca ctgggagcag ctccagcatt ggaggtgatt atgtatcctg gtaccaacag
      241 ctcccaggaa cgacccccaa actcctcatc tatcaaaata ataagctacc ctcaggggtt
      301 tctgaccgat tctctggctc caagtctggt acctcagcct ccctgaccat cactgggctc
      361 cagactgagg atgaggctga ttactactgc ctgtcctatg acagcagcct gagtgctcat
      421 tacatcttcg gtcctgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg
      481 gtcactctgt tcccg
//
LOCUS       KCVO01000549             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:13973:6827
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000549
VERSION     KCVO01000549.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:13973:6827"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..429
                     /note="immunoglobulin light chain variable region"
     V_region        102..429
     V_segment       102..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72578.1"
                     /translation="DYHCFSTDSSGYHRGLF"
     J_segment       393..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           93 a          144 c          126 g          104 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccaaaaaa atttgcttct tggttccagc agaagccagg ccagtcccct gtgctgatca
      241 tctatgacga cagcaaacgg ccctctggga tccctgagag attatctggc tccagctcag
      301 ggacagtggc caccttgact atcattgggg cccaggtgga ggatgaagct gactaccact
      361 gtttctcaac agatagcagt ggttatcata ggggcttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000550             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:21894:3269
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000550
VERSION     KCVO01000550.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21894:3269"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72579.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          161 c          124 g          109 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catatactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtactggagt gttgttcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 cct
//
LOCUS       KCVO01000551             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:7530:4573
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000551
VERSION     KCVO01000551.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:7530:4573"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..421
                     /note="immunoglobulin light chain variable region"
     V_region        101..421
     V_segment       101..381
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72580.1"
                     /translation="DYYCQVWDSNSDVLF"
     J_segment       384..421
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           87 a          138 c          139 g           95 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctgcacagac tctgtggtcc cctatgaatt gactcagcca
      121 cgctcagtgt ccgtgtcccc aggacagacg gccaggatca cctgtgggag agacagtatt
      181 ggaagtagaa gtgtgcagtg gtaccagcag aagccaccgc aggcccttgt gctggtcatg
      241 tatgctgata gcgaacggcc ctcagggatc cctgagcgat tctctggctc caatttaggg
      301 aacaccgcca ccctgaccat cagcggcgtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtaatag tgatgtgtta ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000552             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:14082:15293
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000552
VERSION     KCVO01000552.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14082:15293"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..385
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72581.1"
                     /translation="DYYCQVWDSTSDVLF"
     J_segment       388..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           87 a          144 c          136 g           96 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactgcac agactctgtg gtctcctatg aattgactca
      121 gccacgctca ctgtccgtgt ccccaggaca gacggccagg atcacctgtg ggggagacag
      181 cattggaagt agaagtgtgc agtggtacca gcagaagcca ccgcaggccc ttgtactagt
      241 catctatgct gataccgaac ggccctcagg gatccctgag cgattctctg gctccaattt
      301 agggaacacc gccaccctga ccatcagcgg cgtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta ctagtgatgt gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000553             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:11917:15437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000553
VERSION     KCVO01000553.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:11917:15437"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..369
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72582.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       377..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           90 a          140 c          118 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctttggaga tgcattgcca aaaaagtatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtact gttcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag ggggaggatg aagctgacta ctactgttat tcaatggata
      361 gcagtggtac gcagagcatc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000554             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:15961:7636
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000554
VERSION     KCVO01000554.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15961:7636"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..408
                     /note="immunoglobulin light chain variable region"
     V_region        88..408
     V_segment       88..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72583.1"
                     /translation="DYYCYSGDSSGDGFF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           88 a          137 c          123 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagccgcct atgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaattatg
      181 cgtattggta ccagcagaaa ccaggccagt cccctgtgtt gatcatctct gacgacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcggggaca gtggccacct
      301 tgactatcag gggggcccag gtggaggatg aaggtgacta ctactgttat tcaggagaca
      361 gcagtggtga tggctttttc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000555             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:8652:20252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000555
VERSION     KCVO01000555.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8652:20252"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..416
                     /note="immunoglobulin light chain variable region"
     V_region        86..416
     V_segment       86..379
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72584.1"
                     /translation="DYYCGAWDSSLSTRLF"
     J_segment       381..416
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           86 a          149 c          117 g          102 t
ORIGIN      
        1 acatggggca ctcaggacag tctccagcat ggcctggtct cctctcctcc tcacccttct
       61 cattcactgc acagggtcct gggcccagtc tgtgctgacg cagccgccct cagtgtctgg
      121 ggaccccggg cagagggtca ccatctcgtg cactgggagc agctccaaca ttggaggtta
      181 ttttgtatac tggtaccagc agttcccagg aacagccccc aaactcctca tctatgacaa
      241 taataagcga ccctcaggga tttctgaccg attctctggc tccaagtctg gtacctcagc
      301 ctccctgacc atcactgggc tccagcctgg ggatgaggct gattattact gcggagcatg
      361 ggatagcagc ctgagtactc gcttattcgg aggagggacc cggctgaccg tcctaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000556             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:18109:14081
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000556
VERSION     KCVO01000556.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18109:14081"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72585.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          156 c          128 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag caggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgttgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggcagtaac agtgtgtcct ggtacctgca gctcccagaa
      241 acggctccca aactcctcat ctattataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cccgtcagcc tccctggcca tcagtgggct cgagaccgaa
      361 gatgaggctg attattactg cgcagtatgg gatgatagcc tgagcggtgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01000557             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:23516:7946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000557
VERSION     KCVO01000557.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:23516:7946"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72586.1"
                     /translation="DYFCAAWDDSLNSPFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          155 c          115 g          106 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaac
      181 attggaagta attatgtaaa ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 atctatttta ctaatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattatttc
      361 tgtgcggcat gggatgacag cctgaacagt cccttcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000558             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:15544:4169
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000558
VERSION     KCVO01000558.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15544:4169"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72587.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       405..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           85 a          160 c          119 g          109 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgac gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgaga
      361 ctgattatta ctgcagctca tacgcaagca ctaccacttg gcttttcggc ggagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000559             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:5133:17615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000559
VERSION     KCVO01000559.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:5133:17615"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72588.1"
                     /translation="DYYCYSRDGSENQSVF"
     J_segment       379..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           96 a          135 c          116 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 tatattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaggacaaca
      241 aacggccctc tgggattcct gagagattct ccggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aaggtgacta ttactgttat tcaagagatg
      361 gtagtgaaaa tcaaagcgtc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000560             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:24277:21696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000560
VERSION     KCVO01000560.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24277:21696"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72589.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       395..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          144 c          139 g           97 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gtctcctatg agctcactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggaggcaa
      181 tgttggaact gattatgtcc actggtatca acagaagcca ccgcaggccc ctgtggtggt
      241 catccattat aatagtgacc ggccttcagg gatccctgag cgattctctg gctccaaatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ccgactatta
      361 ctgtcaggtg tgggacagta ggagtgatca tagtttattg ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000561             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:10618:14639
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000561
VERSION     KCVO01000561.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:10618:14639"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72590.1"
                     /translation="DYYCSSYTTSSTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          157 c          123 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catatacaac cagtagcact tgggtcttcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000562             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:20091:2973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000562
VERSION     KCVO01000562.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:20091:2973"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72591.1"
                     /translation="DYYCSSYADTTTWLF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           85 a          160 c          121 g          107 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgac gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacgcagaca ctaccacttg gctattcggc ggagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000563             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:14255:17633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000563
VERSION     KCVO01000563.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14255:17633"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..442
                     /note="immunoglobulin light chain variable region"
     V_region        113..442
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72592.1"
                     /translation="DYFCAVWDDSLSGVLF"
     J_segment       407..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>481
                     /gene="IGLC"
BASE COUNT           90 a          154 c          126 g          111 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcctcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggatg agtgtcacca tctcctgttc
      181 tggaagcacc tccaacatcg gaagtaacag tgtgtcctgg tacctgcagc tcccggaaac
      241 ggctcccaaa ctcctcatct attataatga tcggcgatcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggcc cgtcagcctc cctggccatc agtgggctcg agaccgaaga
      361 tgaggctgat tatttctgcg cagtatggga tgatagcctg agcggtgtgt tattcggagg
      421 agggacccga ctgaccgtcc taagtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01000564             448 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:21929:13618
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000564
VERSION     KCVO01000564.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 448)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:21929:13618"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..410
                     /note="immunoglobulin light chain variable region"
     V_region        86..410
     V_segment       86..373
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <335..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72593.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       377..410
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>448
                     /gene="IGLC"
BASE COUNT           91 a          131 c          130 g           96 t
ORIGIN      
        1 acatggggag atctcctcca gcagcagctc ctgacgctgc tgatttgcat cacgggctgt
       61 tctcttcagc aaaggctctg cggtctccta tgagctcact cagccaccct cggtgtcagt
      121 gtccccagga cagacggcca ggatcacctg tgggggaggc aatgttggaa gtgaatatgt
      181 ccactggtat caacagaagc caccgcaggc ccctgtggtg gtcatctatt ataatactga
      241 ccggccctca gggatccctg agcgattctc tggctccaaa tcagggaaca ccgccaccct
      301 gaccatcagc ggggtcgagg ccggggatga ggctgactat tactgtcagg tgtgggacag
      361 taggagtgat catagtttat tgggaggagg gacccggctg accgtcctag gtcagcccaa
      421 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000565             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:4329:13916
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000565
VERSION     KCVO01000565.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:4329:13916"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..436
                     /note="immunoglobulin light chain variable region"
     V_region        91..436
     V_segment       91..400
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72594.1"
                     /translation="DYYCVIWHNNAWVF"
     J_segment       401..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           92 a          151 c          118 g          113 t
ORIGIN      
        1 acatgggggg cagggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcg cagcctgtgc tgactcagcc aacctccctc
      121 tcagcatctc ctggagcatc agccagactc acctgcacct tgagcagtga catcagtgtt
      181 ggtagttaca ggatattctg gtaccagcag aagccaggga gtcctccccg gtatcttctg
      241 aattaccaca cagactcaga taaacaccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg cttcggccaa tgcagggatt tttctcatct ctgggctcca gtctgaggat
      361 gaggctgact attactgtgt gatttggcac aacaatgctt gggttttcgg cggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000566             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:10841:7697
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000566
VERSION     KCVO01000566.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:10841:7697"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..454
                     /note="immunoglobulin light chain variable region"
     V_region        130..454
     V_segment       130..417
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72595.1"
                     /translation="DYYCYSTDTSGDHRVF"
     J_segment       419..454
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           98 a          152 c          136 g          106 t
ORIGIN      
        1 acatggggaa gagaagccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactccccc tcctcacttt ctgcacaggc
      121 tctgcagcct cctatgagct gacacagcca ccctcggtgt cagtgtcccc aggacagacg
      181 gccaggatca cctgctctgg agatgcattg ccaaaaaaat ttgctttttg gttccagcag
      241 aagccaggcc agtcccctgt gttgatcatc tatgaggaca ccaaacggcc cgctgggatc
      301 cctgagagat tctctggctc cagctcaggc acagtggcca ccttgactgt cactggggcc
      361 caggtggagg atgaagctga ctactactgt tactcaacag ataccagtgg tgatcatagg
      421 gtgttcggcg gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      481 actctcttcc cg
//
LOCUS       KCVO01000567             495 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:14456:8058
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000567
VERSION     KCVO01000567.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 495)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14456:8058"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..457
                     /note="immunoglobulin light chain variable region"
     V_region        124..457
     V_segment       124..417
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>429
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72596.1"
                     /translation="DYYCLSYDSSLSAHYIF"
     J_segment       421..457
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        458..>495
                     /gene="IGLC"
BASE COUNT           95 a          169 c          123 g          108 t
ORIGIN      
        1 acatgggggg gggaagctct gcttcagctg tgggcacagg aggcagcact caggacagtc
       61 tccagcatgg cctcgtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg
      121 gcccagtctg tgctgacaca gccaccctca gtgtctgggg ccccagggca gagggtcacc
      181 atctcgtgca ctgggagcag ctccagcatt ggaggtgatt atgtctcctg gtaccaacag
      241 ctcccaggaa cgacccccaa actcctcatc tatcaaaata ataagcgacc ctcaggggtt
      301 tctgaccgat tctctggctc caagtctggt ccctcagcct ccctgaccat cactgggctc
      361 cagactgagg atgagactga ttactactgc ctgtcctatg acagcagcct gagtgctcac
      421 tacatcttcg gtcctgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg
      481 gtcactctgt tcccg
//
LOCUS       KCVO01000568             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:21003:4105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000568
VERSION     KCVO01000568.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21003:4105"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72597.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       391..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          145 c          126 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctacccccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcagacggc cctctgggat ccctgagaga ttctctgcct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccagggggag gatgaagctg actactactg
      361 ttattcaatg gatagcagtg gtactcagag catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000569             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:20452:6086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000569
VERSION     KCVO01000569.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20452:6086"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..421
                     /note="immunoglobulin light chain variable region"
     V_region        90..421
     V_segment       90..381
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <345..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72598.1"
                     /translation="DYYCQSSDTSLNDHVLF"
     J_segment       386..421
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>461
                     /gene="IGLC"
BASE COUNT           92 a          155 c          110 g          104 t
ORIGIN      
        1 acatgggggc agcactcagg acagtctcca gcatggcctc gtctcctctc ctcctcaccc
       61 ttctcattca ctgcacaggg tcctgggccc agtctgtgct gacacagccg ccctcagtgt
      121 ctggggcccc agggcagagg gtcaccatct cctgcactgg gagcagctcc aacattggag
      181 gttattatgt atactggtac cagcaactcc caggaatggc ccccaaactc ctcatctatg
      241 acaataataa gcgaccctca ggggtttctg accgattctc tggctccaag tctggtacct
      301 cagcctccct gaccatcact gggctccaga ctgaggatga ggctgattat tactgccaat
      361 cctctgacac cagcctaaat gatcatgtgt tattcggagg agggacccgg ctgaccgtcc
      421 tcggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000570             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:18340:20481
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000570
VERSION     KCVO01000570.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18340:20481"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72599.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       388..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          144 c          125 g          100 t
ORIGIN      
        1 acatgggggg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactccccc tcctcacttt ctgcacaggc tctgcagcct cctctgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg aaatgcattg
      181 ccagaatact atgcttattg gttccagcag aagccaggcc agtcccctgt ggcgatcatc
      241 tatgaggaca acaaacggcc ctctgggatc cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cagtggggcc caggtagagg atgaggctga ctactactgt
      361 tactcaacag atagcagtgg tactaatggc ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000571             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:21388:15849
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000571
VERSION     KCVO01000571.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21388:15849"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..426
                     /note="immunoglobulin light chain variable region"
     V_region        106..426
     V_segment       106..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72600.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          141 c          141 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtcacctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcattggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttgtgctgg
      241 tcatctttgc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000572             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:25736:18829
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000572
VERSION     KCVO01000572.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:25736:18829"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72601.1"
                     /translation="DYYYSSYTSTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          160 c          118 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tacagctcat acacaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000573             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:15801:17717
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000573
VERSION     KCVO01000573.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:15801:17717"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72602.1"
                     /translation="DYYCAAWDDSLSSPLF"
     J_segment       393..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          149 c          117 g          109 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagtttcaac
      181 attggaagta attatgtaaa ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 atctatttta gtaatcagcg gccctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcat gggatgatag tctgagcagt cccttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000574             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:18524:11109
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000574
VERSION     KCVO01000574.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18524:11109"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72603.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       375..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           91 a          142 c          117 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct ctgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaaa tgcattgcca gaatactatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtggc gatcatctat gaggacaaca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtagaggatg aggctgacta ctactgttac tcaacagata
      361 gcagtggtac taatggctta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000575             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:21857:9665
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000575
VERSION     KCVO01000575.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:21857:9665"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72604.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          142 c          139 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagactctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaaacc agcgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga acgattctct ggctccaaat
      301 cagggagcgc cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000576             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:12256:19849
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000576
VERSION     KCVO01000576.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12256:19849"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72605.1"
                     /translation="DYYCYSTDNTDTHRGFF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           90 a          141 c          117 g          104 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatctcct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag gcaggccagt cccctgtgtt gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggttccag ttcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaaccgata
      361 acactgatac tcataggggc ttcttcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000577             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:14456:18799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000577
VERSION     KCVO01000577.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14456:18799"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72606.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       393..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          142 c          124 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaagac gacaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaata gatagtagtg gtagtcatag cgtcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000578             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:16781:18946
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000578
VERSION     KCVO01000578.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16781:18946"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..419
                     /note="immunoglobulin light chain variable region"
     V_region        89..419
     V_segment       89..383
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <347..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72607.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       384..419
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT           79 a          148 c          119 g          111 t
ORIGIN      
        1 acatggggag cactctcagg acgtctccac catggcctgg gctctgctcc tcctcaccct
       61 cctcactcag ggcacaggat cctgggctca ggctgccctg actcagtctc cctctgtgtc
      121 tgggtctcct ggacagtcgg tcaccatttc ctgcactgga accagcagtg acattggtgg
      181 ttttgagcgt gtctcctggt accaacagca cccaggcaaa gcccccaaac tcttgattta
      241 tgaggtcagt tatcggccct caggggtctc tgatcgcttc tctggttcca agtctggcaa
      301 cacggcctcc ctgatcatct ctgggctcca ggctgaggac gaggctgatt attattgcag
      361 ctcatacgca agtagtagta cttgggtatt cggcggaggg acccggctga ccgtcctagg
      421 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000579             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:11420:12820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000579
VERSION     KCVO01000579.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11420:12820"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72608.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           89 a          156 c          131 g          110 t
ORIGIN      
        1 acatgggggg ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt gaccatctcc
      181 tgcactggga gcagttccaa cattggaggt tattatgtgc agtggtacca gcagcttcca
      241 ggaacggccc ccaaactcct catgtatgaa aataataagc gaccctcagg ggtttctgat
      301 cgattctctg gctcccagtc tggtacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gcctgagtgc cgtgttattc
      421 ggagcaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01000580             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:22682:14488
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000580
VERSION     KCVO01000580.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:22682:14488"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72609.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           85 a          157 c          120 g          111 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggttcca acagcaccca ggcaaagccc
      241 ccaaactcat gatttgtgac gtcagtaatc ggccctcagg ggtctctact cacttctctg
      301 gttccaagtc tggcaatacg gcctccctga tcatctctgg actccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacgcaagca gtagcacttg ggttttcggc ggagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000581             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:18354:4771
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000581
VERSION     KCVO01000581.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18354:4771"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72610.1"
                     /translation="DYYCQVWDSSSDHILF"
     J_segment       395..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          145 c          137 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagttgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaga taaatatgta cactggtacc agcagaagcc accgcgggcc cctgtgctgg
      241 tcatctacta tgatagtgac cggccctcat ggatccctga gcgattctct gggtccaaat
      301 cagggatcac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc atatcttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000582             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:14161:3837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000582
VERSION     KCVO01000582.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14161:3837"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72611.1"
                     /translation="DYYCQVWDSSSDHIFF"
     J_segment       399..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          147 c          135 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaga taaatatcta cactggtacc agcagaagcc accgcgggcc cctgttctgg
      241 tcatctacta tgatagtgac cggccctcat ggatccctga gcgattctct gggtccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc atatcttttt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000583             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:9028:18528
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000583
VERSION     KCVO01000583.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:9028:18528"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72612.1"
                     /translation="DYYCLIWHNNVWIF"
     J_segment       408..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          154 c          116 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctccccc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gccgactcag ccaacctccc
      121 tctcagcatc tcctggcgca tcagccagac tcacctgcac cttgaacagt gacttcagtg
      181 ttggtagtta cagggtattc tggtaccaac agaagccagg gagtcctccc cggtatcttc
      241 tgacctacca cacagactca gataaagacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt ttgatttggc acaacaatgt ttggattttc ggcgggggga
      421 cccggctgat cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000584             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:12189:14067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000584
VERSION     KCVO01000584.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12189:14067"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72613.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           83 a          162 c          119 g          109 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac cctttcctgc actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggtacca acaccaccca ggcaaagccc
      241 ccaaactcat gatttatgac gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacgcaagca cttccacttg gctattcggc ggagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000585             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:14339:16808
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000585
VERSION     KCVO01000585.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14339:16808"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..453
                     /note="immunoglobulin light chain variable region"
     V_region        120..453
     V_segment       120..413
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72614.1"
                     /translation="NYYCLSYDNSLSAHYIF"
     J_segment       416..453
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           98 a          165 c          118 g          110 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctc gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctatgct gacacagcca ccctcagtgt ctggggcccc agggcagagg gtcaccatct
      181 cgtgcactgg gagcagctcc agcattggag gtgattatgt gtcctggtac caacagctcc
      241 caggaacgac ccccaaactc ctcatctatc aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtacct cagcctccct gaccatcact gggctccaga
      361 ctgaggatga ggctaattac tactgcctgt cctatgacaa cagtctgagt gctcattaca
      421 tcttcggtcc tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca
      481 ctctgttccc g
//
LOCUS       KCVO01000586             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:17648:14325
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000586
VERSION     KCVO01000586.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17648:14325"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72615.1"
                     /translation="DYYCQSGDSSSNHYIF"
     J_segment       392..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          104 a          137 c          121 g          104 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgttagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatgctc ggtggttcca gcagaagcca ggccaggccc ctgtgctggt
      241 gatatataaa gacactgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaata cttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca ggagacagca gttctaatca ttacatcttc ggtgctggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCVO01000587             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:18008:9615
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000587
VERSION     KCVO01000587.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18008:9615"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72616.1"
                     /translation="DYYCQVWDSSSDHPIF"
     J_segment       395..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          145 c          137 g           99 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acgttggaag tgaatatgtg cactggtatc agcagaagtc agcgcaggcc cctgtggtgg
      241 tcatctatta ttatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc atcccatctt cggtactggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01000588             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:8350:14719
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000588
VERSION     KCVO01000588.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8350:14719"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72617.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           87 a          155 c          122 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccagactg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000589             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:14407:4151
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000589
VERSION     KCVO01000589.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14407:4151"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..444
                     /note="immunoglobulin light chain variable region"
     V_region        115..444
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72618.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       409..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>483
                     /gene="IGLC"
BASE COUNT           93 a          155 c          127 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagtaac agtgtgtcct ggtacctgca gctcccagaa
      241 acggctccca aactcctcat ctattataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cccgtcagcc tccctggcca tcagtgggct cgagaccgaa
      361 gatgaggctg attattactg cgcagtatgg gatgatagcc tgagcggtgt gttattcgga
      421 ggagggaccc gactgaccgt cctaagtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01000590             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:20870:9956
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000590
VERSION     KCVO01000590.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20870:9956"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72619.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       377..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           89 a          142 c          118 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaagtatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 gacggccctc tgggatccct gagagattct ctgcctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag ggggaggatg aagctgacta ctactgttat tcaatggata
      361 gcagtggtac tcagagcatc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000591             284 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:17122:3199
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000591
VERSION     KCVO01000591.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 284)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17122:3199"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..246
                     /note="immunoglobulin light chain variable region"
     V_region        1..246
     V_segment       1..211
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <177..>218
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72620.1"
                     /translation="DYYCFVYYSGTQFF"
     J_segment       216..246
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        247..>284
                     /gene="IGLC"
BASE COUNT           64 a           91 c           70 g           59 t
ORIGIN      
        1 cagtcaccag tggtaacttt ccaaactggt tccagcagaa acctggacaa gtccccaggg
       61 gactgattta caatacaaac aacaaacact cctggacccc tgcccggttc tcaggctccc
      121 tcgctggggg caaagctgcc ctgacactgt caggagcaca gcccgaggac gaggctgatt
      181 attactgctt cgtgtactat agtggtactc aattcttcgg aggagggacc cggctgaccg
      241 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000592             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:11545:3666
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000592
VERSION     KCVO01000592.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:11545:3666"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72621.1"
                     /translation="DYYCQVWDSSTDHTLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          144 c          138 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtactgatc atactttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000593             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:13560:17607
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000593
VERSION     KCVO01000593.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:13560:17607"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    59..383
                     /note="immunoglobulin light chain variable region"
     V_region        59..383
     V_segment       59..346
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <308..>355
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72622.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       350..383
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        384..>421
                     /gene="IGLC"
BASE COUNT           83 a          129 c          120 g           89 t
ORIGIN      
        1 acatgggggg acccttctcc tcctcggcct ccttgcttac tgcacaggct ctgcggtctc
       61 ctataacctc actcagccac cctcggtgtc agtgtcccca ggacagacgg ccaggatcac
      121 ctgtggggga ggcaatgttg gaactgaata tgtccactgg tatcaacaga agccaccgca
      181 ggcccctgtg gtggtcatcc attataatag tgaccggccc tcagggatcc ctgagcgatt
      241 ctctggctcc aaatcaggga acaccgccac cctgaccatc agcggggtcg aggccgggga
      301 tgaggctgac tattactgtc aggtgtggga cagtaggagt gatcatagtt tattgggagg
      361 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      421 g
//
LOCUS       KCVO01000594             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:13711:8364
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000594
VERSION     KCVO01000594.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13711:8364"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..421
                     /note="immunoglobulin light chain variable region"
     V_region        97..421
     V_segment       97..383
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <346..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72623.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       389..421
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           96 a          138 c          120 g          105 t
ORIGIN      
        1 acatgggggc tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta
       61 ctccccctcc tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc
      121 tcggtgtcag tgtcccctgg acagacggcc aggatcacct gctctggaga tgcattgccg
      181 aaaaaatatg tatattggtt ccagcagaag ccaggccagt cccctgtctt gatcatctat
      241 gaggacaaca aacggccctc tgggattcct gagagattct ctggctccag ctcagggaca
      301 gtggccacct tgactctcag tggggcccag gtggaggatg aaggtgacta ctattgttac
      361 tcaagagata gtagtgaaaa tcaaagtgtc ttcggtgctg ggacccggct caccgtccta
      421 ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000595             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:12639:9084
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000595
VERSION     KCVO01000595.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12639:9084"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..431
                     /note="immunoglobulin light chain variable region"
     V_region        107..431
     V_segment       107..397
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72624.1"
                     /translation="DYYCCSYAGSYLF"
     J_segment       398..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           84 a          159 c          122 g          104 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac caacaacatc caggcacagc
      241 ccccaaactc atgatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tgcctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgctgct catatgcagg cagctactta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000596             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:25583:6446
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000596
VERSION     KCVO01000596.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:25583:6446"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..213
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72625.1"
                     /translation="DYYCQSYDTRLRAWVF"
     J_segment       215..251
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           62 a           90 c           72 g           65 t
ORIGIN      
        1 acatggggga gattattttg tacagtggta ccaacagctc ccaggaacgg cccccaaact
       61 cctcatctat gaaaatgata aacggccctc aggagtttct gatcgattct ctggctccca
      121 gtctggaacc tcagcctccc tgaccatcac tggactccag tctgaggatg aggctgatta
      181 ctactgccag tcctatgaca ccagattgag ggcctgggta ttcggcggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000597             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:16164:19082
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000597
VERSION     KCVO01000597.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:16164:19082"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72626.1"
                     /translation="DYYCAAWDDSLNSPFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          155 c          114 g          106 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaac
      181 attggaagta attatgtaaa ctggtaccag caactcccag gaacggcccc caaactcctc
      241 atctatttta ctaatcagcg accctcaggg gtccctgtcc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcggcat gggatgacag cctgaacagt cccttcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000598             429 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:21549:14317
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000598
VERSION     KCVO01000598.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 429)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21549:14317"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    61..391
                     /note="immunoglobulin light chain variable region"
     V_region        61..391
     V_segment       61..354
                     /gene="IGLV8-111"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <319..>363
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72627.1"
                     /translation="DYYCAVYMGSGIDVF"
     J_segment       355..391
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        392..>429
                     /gene="IGLC"
BASE COUNT           79 a          134 c          112 g          104 t
ORIGIN      
        1 acatggggct ggatgatgct tctcctcgga ctccttgctt atggctcagg agtggattct
       61 gagactgtgg tgacccagga gccatcgttg tcagtgtccc ctggaggaac agtcacactc
      121 acctgtggcc tgagctctgg ctcagtctct accgataact accccagctg gtaccagcag
      181 accccaggcc aggctccacg catgctcctc ttcaacacaa acactcgccc ttctggggtc
      241 cctactcgct tctctggctc catccttggg aacaaagctg ccctcaccgt cacgggggct
      301 caggcagacg atgaatctga ttattactgt gcggtgtaca tgggtagtgg cattgatgtg
      361 ttcggaagtg gcaccaagtt gaccgtcctc ggtcagccca aggcttcccc cttggtcact
      421 ctgttcccg
//
LOCUS       KCVO01000599             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:20503:16381
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000599
VERSION     KCVO01000599.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20503:16381"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72628.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          142 c          125 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgagaga atctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagtagtg gtaatcatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000600             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:12706:13231
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000600
VERSION     KCVO01000600.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:12706:13231"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..424
                     /note="immunoglobulin light chain variable region"
     V_region        101..424
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72629.1"
                     /translation="DYYCYSADSSSNHSFF"
     J_segment       390..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>463
                     /gene="IGLC"
BASE COUNT           94 a          146 c          121 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaagac accaaacggc cctctgggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagcc gatagcagtt ctaatcatag cttcttcgga ggagggaccc ggctgaccgt
      421 cctaagtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000601             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:19420:15909
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000601
VERSION     KCVO01000601.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19420:15909"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72630.1"
                     /translation="DYYCQSYDSRLSAHVF"
     J_segment       415..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           84 a          158 c          131 g          112 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctggc gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc gccgtctcct
      181 gcactgggag cagctccaac tttggagatt tttatgtaca gtggtaccag cagtttccag
      241 gaacggcccc caaactcctc atctatgaaa agaataagcg cccctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggttcctccg cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag gctgagtgct catgtattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01000602             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:17838:16379
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000602
VERSION     KCVO01000602.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:17838:16379"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72631.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           88 a          160 c          125 g          110 t
ORIGIN      
        1 acatggggtg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gattcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtactggagt gttgttcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01000603             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:11085:10646
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000603
VERSION     KCVO01000603.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:11085:10646"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72632.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       392..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           90 a          144 c          126 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gacagtagtg gtaattatgt cttcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000604             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:21294:14753
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000604
VERSION     KCVO01000604.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:21294:14753"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72633.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           94 a          144 c          123 g          100 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctctgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgt
      181 caaaatacta tgcttattgg ttccagcaga agccaggcca gtcccctgtg gcgatcatct
      241 atgaggacaa caaacggccc tctgggatcc ctgagagaat ctctggctcc agctcaggga
      301 cagtggccac cttgactatc agtggggccc aggtcgagga tgaagctgac tactactgtt
      361 actcaacaga tagcagtggt actaatggct tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000605             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:14499:13373
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000605
VERSION     KCVO01000605.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14499:13373"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72634.1"
                     /translation="DYYCAAWDDSLSSPFF"
     J_segment       413..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           91 a          159 c          122 g          109 t
ORIGIN      
        1 acatggggac cttcagctgc gggtacagaa ggcaggactc aggataatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag ccaccctcaa cgtctggggc tcccgggcag agtgtcacca tctcttgctc
      181 tggaagcagc tccaacattg gaagtaatta tgtaaactgg taccagcagc tcccaggaac
      241 ggcccccaaa ctcctcatct attttagtaa tcagcgaccc tcaggggtcc ctgaccgatt
      301 ctctggctct aagtctggca cctcagcctc cctggccatc actggtctcc gatctgagga
      361 tgaggctgat tattactgtg cggcatggga tgacagcctg agcagtccct tcttcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01000606             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:22963:9709
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000606
VERSION     KCVO01000606.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22963:9709"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72635.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          160 c          121 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaactaat agtgtatcct ggtaccagca gctcccagaa
      241 acggctccca aactcctcat ctattataat gatcgacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gataacagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCVO01000607             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:22769:12923
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000607
VERSION     KCVO01000607.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22769:12923"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72636.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          140 c          141 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccaccctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gtattggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttgtgctgg
      241 tcatgtatgc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000608             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:23048:8969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000608
VERSION     KCVO01000608.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:23048:8969"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72637.1"
                     /translation="DYYCSSYASSSTWIF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          156 c          123 g          105 t
ORIGIN      
        1 acaggggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcata atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcag tagcacttgg atattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000609             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:4980:10465
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000609
VERSION     KCVO01000609.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:4980:10465"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72638.1"
                     /translation="EYHCFSTDSSGNHRGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           94 a          144 c          124 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcact
      181 gccaaaaaaa ttttcttctt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgacgac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcattggggc ccaggtggag gatgaaactg agtaccactg
      361 tttctcaaca gatagtagtg gtaatcatag gggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000610             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:17007:14127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000610
VERSION     KCVO01000610.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:17007:14127"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..395
                     /gene="IGLV10-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72639.1"
                     /translation="DYYCSSWDSSLSVVFF"
     J_segment       397..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT          104 a          156 c          124 g           88 t
ORIGIN      
        1 acatggggaa agcagagctt cggcaagcac agtgggaatc cgcaccatgc cctgggctct
       61 gctcctcctg accctcctca ctcactctgc agtgtcagtg gtccaggcag ggctgactca
      121 gccaccctca gtgtccaagg acttgagaca gacggccacg ctcacctgca ctggaaacag
      181 caacaatgtt ggcaaccacg gagcagcttg gctgcagcag caccagggcc accctcccaa
      241 gctgctgtcc tacaggaata acaaccggcc ctcggggatc tcagagagat tctctgcatc
      301 caggtcagga aacacagcct ccctgaccat caccggactc caacctgagg atgaggctga
      361 ctattactgc tcaagttggg acagtagcct cagtgttgtg tttttcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000611             455 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:11113:14324
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000611
VERSION     KCVO01000611.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 455)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 455)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:11113:14324"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..417
                     /note="immunoglobulin light chain variable region"
     V_region        90..417
     V_segment       90..377
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <339..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72640.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       381..417
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>455
                     /gene="IGLC"
BASE COUNT           91 a          141 c          122 g          101 t
ORIGIN      
        1 acatggggag gcagagctct gggtgtctca ccatggcctg gattcctctc ctactccccc
       61 tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca ccctcggtgt
      121 cagtgtcccc aggacagacg gccaggatct cctgctctgg agatggattg ccaaaaaaat
      181 ttgcttcttg gttccagcag aaggcaggcc agtcccctgt gctgatcatc tatgaggaca
      241 gcaaacggcc ctctgggatc cctgagagat tctctggctc cagttcaggg acagtggcca
      301 ccttgactat cggtggggcc caggtggagg atgaagctga ctactactgt tactcaacag
      361 ataacagcga tactcatagg ggcttcttcg gaggagggac ccggctgacc gtcctaggtc
      421 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000612             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:17870:15093
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000612
VERSION     KCVO01000612.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17870:15093"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72641.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           90 a          141 c          127 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaggccaggc cagtcccctg tgttgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagtagtg gtaattatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000613             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:5717:6372
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000613
VERSION     KCVO01000613.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:5717:6372"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72642.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       392..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           87 a          141 c          139 g           95 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggtct cctatgacct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaatgtt
      181 ggaagtgaat atgtgcactg gtaccaacag aagccaccgc aggcccctgt ggtggtcatc
      241 cattataata gtgaccggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtagtag tgatcattgt gtattgggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000614             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:19603:5587
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000614
VERSION     KCVO01000614.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19603:5587"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72643.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       411..447
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           95 a          161 c          122 g          107 t
ORIGIN      
        1 acatgggggc gcagcttcag ctgtgggtac agaaggcagg actcaggaca atctccagca
       61 tggcctggtt ccctctcctc ctcaccctcc tcactcactg tgcagggtcc tgggcccagt
      121 ctgtgctgac tcagcctccc tcagcgtctg aggccgccag gaagagtgtc accatctcct
      181 gttctggaag cacctccaac atcggaacta atagtgtatc ctggtaccag cagctcccag
      241 aaacggctcc caaactcctc atctattata atgatcgacg agcctcaggt gtctctgacc
      301 gattctctgg ctccaagtct ggcacgtcag cctccctggc catcagtggg ctccagaccg
      361 aggatgaggc tgattattac tgcgcagcat gggataacag cctgagcggt tacatcttcg
      421 gtgctgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt
      481 tcccg
//
LOCUS       KCVO01000615             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:12971:9415
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000615
VERSION     KCVO01000615.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:12971:9415"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72644.1"
                     /translation="DYYCAAWDNSLNSPLF"
     J_segment       393..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          154 c          115 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggatg atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaac
      181 attggaggta attatgtatc ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 atctattata ataatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgagac tgattattac
      361 tgtgcagcat gggataacag cctgaacagt cccttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000616             396 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:13043:7814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000616
VERSION     KCVO01000616.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 396)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13043:7814"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    28..358
                     /note="immunoglobulin light chain variable region"
     V_region        28..358
     V_segment       28..322
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <286..>330
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72645.1"
                     /translation="DYYCSSYTTSSTWVF"
     J_segment       323..358
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        359..>396
                     /gene="IGLC"
BASE COUNT           75 a          125 c          104 g           92 t
ORIGIN      
        1 acatgggagg gcacaggatc ctgggctcag gctgccctga ctcagtctcc ctctgtgtct
       61 gggtctcctg gacagtcggt caccatttcc tgcactggaa ccagcagtga cattggtgat
      121 tataaccgtg tctcctggta ccaacagcac ccaggcaaag cccccaaact catgatttat
      181 gaggtcagtg atcggccctc aggggtctct gatcgcttct ctggttccaa gtctggcaac
      241 acggcctccc tgatcatctc tgggctccag gctgaggacg aggctgatta ttactgcagc
      301 tcatatacaa ccagtagcac ttgggtcttc ggcggaggga cccggctgac cgtcctaggt
      361 cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000617             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:11779:15791
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000617
VERSION     KCVO01000617.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11779:15791"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72646.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          142 c          139 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcattggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttctactgg
      241 tcatctatgc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000618             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:6120:14556
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000618
VERSION     KCVO01000618.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:6120:14556"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..395
                     /gene="IGLV10-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72647.1"
                     /translation="DYYCSAWDSSLSVVLF"
     J_segment       397..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT          101 a          159 c          128 g           84 t
ORIGIN      
        1 acatggggaa agcagagctt cggcaagcac agtgggaatc cgcaccatgc cctgggctct
       61 gctcctcctg accctcctca ctcactctgc agtgccagtg gtccaggcag ggctgactca
      121 gccaccctca gtgtccgagg gcttgagaca gacggccacg ctcacctgca ctggaaacag
      181 caacaatgtt ggccaccagg gagcaggttg gctgcagcag caccagggcc accctcccaa
      241 actgctgtcc tacaggaata acaaccggcc ctcggggatc tcagagagat tctctgcatc
      301 caggtcaggt aacacagcct ccctgaccat caccggactc cgacctgagg atgaggctga
      361 ctattactgc tcagcatggg acagcagcct cagtgttgtg ctattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000619             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:18460:16356
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000619
VERSION     KCVO01000619.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18460:16356"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72648.1"
                     /translation="DYYCSSYTDSSTWLF"
     J_segment       407..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           83 a          157 c          125 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggagc
      181 cagcagtgac attggtggtt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtga tcggccctct ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacacaga cagtagcact tggcttttcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000620             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:22390:8713
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000620
VERSION     KCVO01000620.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:22390:8713"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72649.1"
                     /translation="DYYCQSYDSTLRAFLF"
     J_segment       414..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           85 a          160 c          125 g          115 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggagatt tttatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaactcctc atctgtgaaa ataataagcg accctcaggt gtctctgatc
      301 gattctctgg ctcccagtct ggttcctcag cctccctgac catcactggc ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcac cttgcgtgct tttttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01000621             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:13239:18100
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000621
VERSION     KCVO01000621.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13239:18100"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72650.1"
                     /translation="DYYCQVWDSSSDHCLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          143 c          140 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaggcc accgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000622             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:26558:6754
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000622
VERSION     KCVO01000622.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:26558:6754"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72651.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          160 c          119 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa catcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000623             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:16513:12178
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000623
VERSION     KCVO01000623.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16513:12178"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..427
                     /note="immunoglobulin light chain variable region"
     V_region        105..427
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72652.1"
                     /translation="DYYCQVWDSSSDHWVF"
     J_segment       392..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>467
                     /gene="IGLC"
BASE COUNT           84 a          147 c          142 g           94 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca caggctctgc ggtctcctat gagctgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggcccg gatcacctgt gggggagaca
      181 acattggaag taaaagtgtg cagtggttcc agcagaagcc accacaggcc cctgtgttgg
      241 tcatttatgg tgataccgaa cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cgggaatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgggtgtt cggcggaggg acccggctga
      421 ccgtcctcgg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000624             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:16687:14054
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000624
VERSION     KCVO01000624.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16687:14054"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..442
                     /note="immunoglobulin light chain variable region"
     V_region        109..442
     V_segment       109..402
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72653.1"
                     /translation="DYYCSLWDSRLSSRVF"
     J_segment       407..442
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>457
                     /gene="IGLC"
BASE COUNT           91 a          142 c          122 g          102 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcaacactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcagcatc tggggccccc gggcagaggg tcaccatctc ctgcactggg
      181 accagctcca acatcggggc gaattattat gtttcctggt accagcagtt cccaggaaca
      241 gcccccaaac tcctcatcta tgaaaataat aagcgaccct ctggggtttc tgaccgattc
      301 tctggctcca agtctggtac ctcagcctcc ctgaccatct ctggactcca atctgaggat
      361 gaggctgatt attactgctc cctatgggat agcagactga gtagtcgggt attcggcgga
      421 gggacccgac tgaccgtcct aggtcagccc aaggctg
//
LOCUS       KCVO01000625             442 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:23235:2821
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000625
VERSION     KCVO01000625.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 442)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 442)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:23235:2821"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    80..401
                     /note="immunoglobulin light chain variable region"
     V_region        80..401
     V_segment       80..367
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <329..>376
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72654.1"
                     /translation="DYYCFSSDSSADYWVF"
     J_segment       368..401
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>442
                     /gene="IGLC"
BASE COUNT           85 a          137 c          117 g          103 t
ORIGIN      
        1 acatggggct gggtgtctca ccatggcctg gattcctctc ctactccccc tcctcacttt
       61 ctgcacaggc tctgcagcct cctatgagct gacacagcca ccctcggtgt cagtgtcccc
      121 aggacagacg gccaggatca cctgctctgg agatgcattg tcagaaaaat atgcttattg
      181 gttccagcag aagccaggcc agtcccctgt gttgatcatc tatgaggaca ccaaacggcc
      241 ctctgggatc cctgagagat tctctggttc cagctcaggg acagtggcca ccttgactat
      301 cagtggggcc caggtggagg atgaagctga ctactactgt ttctcatcag atagcagtgc
      361 tgattattgg gtgttcggcg gagggacccg gctgaccgtc ccaggtcagc ccaaggctgc
      421 cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000626             391 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:19405:9855
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000626
VERSION     KCVO01000626.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 391)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 391)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19405:9855"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    29..353
                     /note="immunoglobulin light chain variable region"
     V_region        29..353
     V_segment       29..316
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <278..>325
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72655.1"
                     /translation="DYYCQVWDSSSDHILF"
     J_segment       319..353
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        354..>391
                     /gene="IGLC"
BASE COUNT           80 a          115 c          114 g           82 t
ORIGIN      
        1 acatgggtac tgcacaggct ctgcggtctc ctatgagttg actcagccac cctcggtgtc
       61 agtgtcccca ggacagacgg ccaggatcac ctgtggggga gacaaccttg gagataaata
      121 tgtacactgg taccagcaga agccaccgcg ggcccctgtg ctggtcatct actatgatag
      181 tgaccggccc tcatggatcc ctgagcgatt ctctgggtcc aaatcaggga tcaccgccac
      241 cctgaccatc agcggggtcg aggccgggga tgaggctgac tattactgtc aggtgtggga
      301 cagtagtagt gatcatatct tattcggagg agggacccgg ctgaccgtcc taggtcagcc
      361 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000627             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:23554:13090
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000627
VERSION     KCVO01000627.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23554:13090"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..406
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72656.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          157 c          126 g          109 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gtgtctgggg cgcccgggca gagggtcacc ctctcctgca
      181 ctgggagcag ctccaacatt ggaggttatt atgtgcagtg gtatcagcag cttccaggaa
      241 cggcccccaa actcctcatc tatgaaaata ataagcgacc ctcaggggtt tctgatcgat
      301 tctctggctc ccagtctggt acctcagcct ccctgaccat cactggactc cagtctgaag
      361 atgaggctga ttattactgc cagtcctatg acagcagcct gagtgccgtg ttattcggag
      421 gagggacccg gctaaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000628             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:11262:4901
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000628
VERSION     KCVO01000628.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11262:4901"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72657.1"
                     /translation="DYYCQVWDSSGDVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          141 c          139 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcaacc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 ccattggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttgtactgg
      241 tcatctatgc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 attgtcaggt gtgggacagt agtggtgatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000629             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:17444:14689
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000629
VERSION     KCVO01000629.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:17444:14689"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72658.1"
                     /translation="DYYCSSYASSSTWIF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          156 c          124 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctgggaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatc atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgat catctctggg ttccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcag tagcacttgg atattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000630             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:14237:20086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000630
VERSION     KCVO01000630.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14237:20086"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..382
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72659.1"
                     /translation="DYYCQSTDSSGYIF"
     J_segment       383..419
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT          103 a          133 c          118 g          103 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgtggcc tcctatgagc tgacacagcc
      121 accttcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 gaaaaaaaat tatgctcagt ggttccagca gaagccaggc caggcccctg tgctgctgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaacagtt accttgacca tcagtcgggc ccaggtagaa gatgaggctg actattattg
      361 tcaatcaaca gacagcagtg gttacatctt cggtgctggg acccggctca ccgtcctagg
      421 tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01000631             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:13675:2812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000631
VERSION     KCVO01000631.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:13675:2812"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72660.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          142 c          140 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctcactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggaggca
      181 atgttggaag tgaatatgtc cactggtatc aagagaagcc accgcaggcc cctgtggtgg
      241 tcatctatta taatactgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt aggagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000632             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:16915:5653
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000632
VERSION     KCVO01000632.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:16915:5653"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72661.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          161 c          126 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagcgggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000633             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:19763:4297
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000633
VERSION     KCVO01000633.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:19763:4297"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72662.1"
                     /translation="DYYCTSYATSITWIF"
     J_segment       404..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          156 c          122 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtgtc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcacctcat acgcaaccag tatcacttgg attttcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000634             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:23837:19904
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000634
VERSION     KCVO01000634.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:23837:19904"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72663.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       393..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          143 c          124 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctacccccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaagac gacaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaata gatagtagtg gtagtcatag cgtcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000635             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:24127:14211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000635
VERSION     KCVO01000635.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:24127:14211"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72664.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           90 a          141 c          120 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatctcct gctctggaga tggattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag gcaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ttcagggaca gtggccacct
      301 tgactatcgg tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagata
      361 acagcgatac tcataggggc ttcttcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000636             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:16373:9908
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000636
VERSION     KCVO01000636.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16373:9908"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..434
                     /note="immunoglobulin light chain variable region"
     V_region        107..434
     V_segment       107..390
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72665.1"
                     /translation="DYYCSSYAGTNRVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           84 a          157 c          124 g          107 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcaggac ttctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accctctcct gcactggaac
      181 cagcagtgat attgggtatt ttaatgctgt gtcttggtac caacaacatc caggcaaggc
      241 ccccaaactc atgatttatg aggtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgcagct catatgcagg caccaacagg gtgttcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000637             494 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:17096:8729
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000637
VERSION     KCVO01000637.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 494)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17096:8729"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..456
                     /note="immunoglobulin light chain variable region"
     V_region        123..456
     V_segment       123..416
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72666.1"
                     /translation="DYYCLSYDSSLSAHYIF"
     J_segment       420..456
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>494
                     /gene="IGLC"
BASE COUNT           94 a          169 c          123 g          108 t
ORIGIN      
        1 acatgggggg ggaagctctg cttcagctgt gggcacagga ggcagcactc aggacagtct
       61 ccagcatggc ctcgtctcct ctcctcctca cccttctcat tcactgcaca gggtcctggg
      121 cccagtctgt gctgacacag ccaccctcag tgtctggggc cccagggcag agggtcacca
      181 tctcgtgcac tgggagcagc tccagcattg gaggtgatta tgtctcctgg taccaacagc
      241 tcccaggaac gacccccaaa ctcctcatct atcaaaataa taagcgaccc tcaggggttt
      301 ctgaccgatt ctctggctcc aagtctggtc cctcagcctc cctgaccatc actgggctcc
      361 agactgagga tgaggctgat tactactgcc tgtcctatga cagcagcctg agtgctcact
      421 acatcttcgg tcctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg
      481 tcactctgtt cccg
//
LOCUS       KCVO01000638             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:9661:6696
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000638
VERSION     KCVO01000638.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9661:6696"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    70..261
                     /note="immunoglobulin light chain variable region"
     V_region        70..261
     V_segment       70..227
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <195..>236
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72667.1"
                     /translation="DYYCQSTDSSGFIF"
     J_segment       230..261
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        262..>302
                     /gene="IGLC"
BASE COUNT           62 a           86 c           82 g           72 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctgtgttg ctgatattta aagacagtga gaggccctca gggatccctg
      121 agcgattctc tagctccagt tcagggacat caattacctt gaccatcagt ggggcccagg
      181 cagaagatga ggctgactat tactgtcaat caacagacag cagtggtttc atcttcggtg
      241 ctgggacccg gctcaccgtc ccaggtcagc ccaaggcttc ccccacggtc actctgttcc
      301 cg
//
LOCUS       KCVO01000639             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:13884:2830
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000639
VERSION     KCVO01000639.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13884:2830"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72668.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           92 a          143 c          128 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc tcctgctctg gagatggatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaaggcaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagttcagg
      301 gacagtggcc accttgacta tcggtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gataacagcg atactcatag gggcttcttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000640             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:25261:6655
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000640
VERSION     KCVO01000640.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:25261:6655"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72669.1"
                     /translation="DYYCQSYDSRLTGHVF"
     J_segment       415..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           86 a          158 c          129 g          112 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtactggc gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accgtctcct
      181 gcactgggag cagctccaac tttggaggtt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaactcctc atctatgaaa ataataagcg tccctcaggg gtttctgacc
      301 gattctctgg ctcccagtct ggttcctccg cctccctgac catcactaga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag gttgactggt catgtattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01000641             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:7417:2488
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000641
VERSION     KCVO01000641.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7417:2488"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72670.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          161 c          123 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000642             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:14037:17130
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000642
VERSION     KCVO01000642.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:14037:17130"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72671.1"
                     /translation="DYYCEAWDDSLSGPVF"
     J_segment       411..445
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          154 c          125 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc aacgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaacat cggaagtaat agtgtatcct ggtaccagca gctcccagaa
      241 acggctccca aactcctcct ctattataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgaagcatgg gatgatagcc tgagcggtcc tgtgttcgga
      421 agtggcacca agttgaccgt cctcggtcag cccaaggctt cccccttggt cactctgttc
      481 ccg
//
LOCUS       KCVO01000643             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:12005:8015
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000643
VERSION     KCVO01000643.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:12005:8015"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72672.1"
                     /translation="EYYCSSYADIYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          162 c          118 g          109 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tggcctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcacgggcac
      181 cagcagtgac atcggtggtt acaactttgt ctcctggtac caacaccatc cagacacagc
      241 ccccaaactc gtgatttatg aggtcactca gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgaatat tactgcagtt catatgcaga catctacaca tttgtgttcg gaagtggcac
      421 caaattgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01000644             341 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:12965:15197
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000644
VERSION     KCVO01000644.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 341)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12965:15197"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..303
                     /note="immunoglobulin light chain variable region"
     V_region        8..303
     V_segment       8..264
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <234..>275
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72673.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       267..303
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        304..>341
                     /gene="IGLC"
BASE COUNT           72 a          101 c           94 g           74 t
ORIGIN      
        1 acatgggggc cagactcccc tgcaccctga gcagtgacct cagtgttggt agtaaaaaca
       61 tgtactggta ccagcagaag ccagggagcg ctcccaggtt attcctgtac tactactccg
      121 actcagacaa gcagctggga cctggggtcc ccaatcgagt ctctggctcc aaggagacct
      181 caagtaacac agcgtttttg ctcatctctg ggctccagcc tgaggacgag gccgattatt
      241 actgtcaggt gtatgacagt actggagtgt tgttcggagg agggacccgg ctgaccgtcc
      301 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000645             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:10857:6503
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000645
VERSION     KCVO01000645.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10857:6503"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..382
                     /note="immunoglobulin light chain variable region"
     V_region        58..382
     V_segment       58..337
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <307..>354
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72674.1"
                     /translation="DYYCQVWDSITAQWVF"
     J_segment       346..382
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        383..>420
                     /gene="IGLC"
BASE COUNT           78 a          132 c          122 g           88 t
ORIGIN      
        1 acatggggga cccttctcct cctcggcctc cttgctcact gcacaggctt tgcggtctcc
       61 tatgagctga ctcagccacg ctcagtgtcc gtgtccccag gacagacggc ccggatcacc
      121 tgtgggggag acaacattgg aagtaaaagt gtgcagtggt tccagcagag gccaccgcag
      181 gcccctgtgc tggtcattta tactgataac cagcggccct cagggatccc tgagcgattc
      241 tctggctcca actcagggaa caccgccacc ctgaccatca gcggggtcga ggccgggaat
      301 gaggctgact attattgtca ggtgtgggac agtattactg ctcagtgggt attcggcgga
      361 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000646             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:15373:13116
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000646
VERSION     KCVO01000646.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:15373:13116"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72675.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       392..424
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          142 c          124 g          103 t
ORIGIN      
        1 acatgggggg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactccccc tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agatgcattg
      181 ccaaaaaagt atgcttattg gttccagcag aagccaggcc agtcccctgt gctgatcatc
      241 tatgaagacg acaaacggcc ctctgggatc cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cagtggggcc caggtggagg atgaagctga ctactactgt
      361 tactcaatag atagtagtgg tagtcatagc gtcttcggtg ctgggacccg gctcaccgtc
      421 ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01000647             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:22835:13970
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000647
VERSION     KCVO01000647.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:22835:13970"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..442
                     /note="immunoglobulin light chain variable region"
     V_region        121..442
     V_segment       121..408
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72676.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       409..442
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           97 a          149 c          130 g          104 t
ORIGIN      
        1 acatggggct agggagccca gctgtgctgt gggctcagga ggcagagctc tgggtgtctc
       61 accatggcct ggattcctct cctactcccc ctcctcactt tctgcacagg ctctgcagcc
      121 tcctatgagc tgacacagcc accctcggtg tcagtgtccc caggacagac ggccaggatc
      181 acctgctctg gagatgcatt gccagaaaaa tatgcttatt ggttccagca gaagccaggc
      241 cagtcccctg tactgatcat caatgaggac agcaaacggc cctctgggat ccctgagaga
      301 ttctctggct ccagctcagg gacagtggcc accttgactc tcagtggggc ccaggtggag
      361 gatgaagctg actactactg ttcctcaaca gatagcagtg gtaattatgt attcggcgga
      421 gggacccgac tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000648             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:12294:10999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000648
VERSION     KCVO01000648.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:12294:10999"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72677.1"
                     /translation="DYYCSSFAGTSTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           85 a          155 c          123 g          110 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aatcgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat aatttttgag gtcagtaatc ggccctcagg ggtctctgat cgcttctctg
      301 gttctaagtc tggcaacacg gcctccctga acatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca ttcgcaggca ctagcacttg ggtcttcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000649             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:21328:8266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000649
VERSION     KCVO01000649.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:21328:8266"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72678.1"
                     /translation="DYYCSSYASSSTWIF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          156 c          123 g          108 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc ataatttatg aggtcagtga tcggccctca ggggtctctg atcgtttctc
      301 tggctccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacgcaag cagtagcact tggatattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000650             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:6763:9407
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000650
VERSION     KCVO01000650.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6763:9407"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72679.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       379..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           92 a          139 c          116 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcaa aaaaagtatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaagacgaca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaatagata
      361 gtagtggtag tcatagcgtc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000651             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:10862:18675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000651
VERSION     KCVO01000651.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:10862:18675"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..395
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72680.1"
                     /translation="DYYCAAWDDSLSSPLF"
     J_segment       398..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           90 a          149 c          121 g          110 t
ORIGIN      
        1 acatgggggg ggtacagaag gcaggactca ggataatctc cagcatggcc tggttccctc
       61 tcgtcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg ctgactcagc
      121 caccctcaac gtctggggct cccgggcaga gtgtcaccat ctcttgctct ggaagcagtt
      181 tcaacattgg aagtaattat gtaaactggt accagcagct cccaggaacg gcccccaaac
      241 tcctcatcta ttttagtaat cagcggccct caggggtccc tgaccgattc tctggctcta
      301 agtctggcac ctcagcctcc ctggccatca ctggtctccg atctgaggat gaggctgatt
      361 attactgtgc agcatgggat gatagtctga gcagtccctt attcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000652             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:19349:14954
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000652
VERSION     KCVO01000652.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:19349:14954"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..403
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72681.1"
                     /translation="DYYCGSYRSGSTFIF"
     J_segment       404..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           82 a          157 c          126 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcgggac gtctccacca tggcttgggc
       61 tctggtcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtccgtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt ataacggtgt ctcctggtac cagcagcact caggcacagc
      241 ccccagactc ctgatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgcggct catataggag tggaagcact ttcatcttcg gtgctgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCVO01000653             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:4028:12701
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000653
VERSION     KCVO01000653.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:4028:12701"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72682.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          143 c          138 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctcactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggaggca
      181 atgttggaag tgaatatgtc cactggtatc aacagaagcc accgcaggcc cctgtggtag
      241 tcatctatta taattctgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt aggagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000654             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:17187:18784
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000654
VERSION     KCVO01000654.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17187:18784"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72683.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       377..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           89 a          141 c          119 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaagtatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 gacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag ggggaggatg aagctgacta ctactgttat tcaatggata
      361 gcagtggtac tcagagcatc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000655             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:12191:13385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000655
VERSION     KCVO01000655.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12191:13385"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72684.1"
                     /translation="EYHCFSTDSTGNHRGLF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           90 a          144 c          118 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acaggcaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca caaaaatttg
      181 cttcttggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gacgacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcac tggggcccag gtggaggatg aagctgagta ccactgtttc tcaacagata
      361 gcactggtaa tcataggggc ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000656             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:16178:12466
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000656
VERSION     KCVO01000656.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:16178:12466"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72685.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          139 c          141 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagattctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggaaaca
      181 gcattggaag tagaagtgtg cagtggtacc agcagaagcc accgctggcc cttgtactgg
      241 tcatctatgc tgatggggaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000657             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:16660:15140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000657
VERSION     KCVO01000657.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16660:15140"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72686.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          156 c          127 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagtaac agtgtgtcct ggtacctgca gctcccagaa
      241 acggctccca aactcctcat ctattataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cccgtcagcc tccctggcca tcagtgggct cgagaccgaa
      361 gatgaggctg attattactg cgcagtatgg gatgatagcc tgagcggtgt gttattcgga
      421 ggaggcaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01000658             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:4706:12246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000658
VERSION     KCVO01000658.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:4706:12246"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72687.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           97 a          144 c          121 g           99 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc catcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcgtt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccagacaa atatgcttat tggtaccggc agaaaccagg ccagtcccct atactgatca
      241 tctatgaaga caacaaacgg ccctctggga tccctgaaag attctctggc tccagttcag
      301 ggacagtggc caccttgact atcactgggg cccaggtgga ggatgaagct gactactact
      361 gttactctgc agacaacagt ggtcagggct cattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000659             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:12734:2611
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000659
VERSION     KCVO01000659.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12734:2611"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72688.1"
                     /translation="DYYCQVWDSITDHSIF"
     J_segment       395..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          148 c          134 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagtctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggggaca
      181 acattggaac tgaatatgtg cactggtacc agcagaagcc accgcaggcc cctgtggtgg
      241 tcatctatta taatagtgac cggccctcag ggatccctga gcgattctca ggctccaaat
      301 cagggaacac cggcaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt attactgatc attccatctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01000660             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:5274:6488
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000660
VERSION     KCVO01000660.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:5274:6488"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72689.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       390..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          142 c          125 g          101 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccagaaaa atatgcttat tggttccagc agaagccagg ccagtcccct gtactgatca
      241 tcaatgagga cagcaaacgg ccctctggga tccctgggag attctctgga tccacctcag
      301 ggacagtggc caccttgact ctcagtgggg cccaggtgga ggatgaagct gactactact
      361 gttcctcaac agatagtagt ggtaattatg tattcggcgg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000661             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:3327:14922
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000661
VERSION     KCVO01000661.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:3327:14922"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72690.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          160 c          120 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtaggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaactaat agtgtatcct ggtaccagca gctcccagaa
      241 acggctccca aactcctcat ctattataat gatcgacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gataacagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCVO01000662             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:20129:4277
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000662
VERSION     KCVO01000662.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20129:4277"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..372
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72691.1"
                     /translation="DYYCYSMDSSTYLGFF"
     J_segment       374..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           91 a          141 c          114 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggct aggatcacct gctctggaga tgcattgcca aaaaaatacg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtatt gatcatctat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaatggata
      361 gcagtactta tcttggcttc ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000663             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:15189:14025
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000663
VERSION     KCVO01000663.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:15189:14025"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..390
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72692.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       391..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          140 c          126 g          103 t
ORIGIN      
        1 acatgggggt gtgggctcag gaggcagagc tctgggtgtc tcaccatggc ctggattcct
       61 ctcctactcc ccctcctcac tttctgcaca ggctctgcag cctcctatga gctgacacag
      121 caaccctcgg tgtcagtgtc tccaggacag acggccagga tcacctgctc tggagatgca
      181 ttgccagaaa aatatgctta ttggttccag cagaagccag gccagtcccc tgtgttgatc
      241 atcaatgagg acagcaaacg gccctctggg atccctgaga gattctctgg ctccagctca
      301 gggacagtgg ccaccttgac tctcagtggg gcccaggtgg aggatgaagc tgactactat
      361 tgttcctcaa cagatagcag tggtaatcat gtattcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000664             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:19951:16235
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000664
VERSION     KCVO01000664.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:19951:16235"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72693.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           83 a          162 c          119 g          109 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggtacca acaccaccca ggcaaagccc
      241 cccaactcat gatttatgac gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacgcaagca cttccacttg gctattcggc ggagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000665             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:17957:18877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000665
VERSION     KCVO01000665.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:17957:18877"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72694.1"
                     /translation="DYYCQVWDSSTDHTLL"
     J_segment       391..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           88 a          142 c          137 g           95 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggtct cctatgagct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaatgtt
      181 ggaagtgaat atgtgcactg gtaccaacag aagccaccgc aggcccctgt ggtggtcatc
      241 cattataata gtgaccggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtagtac tgatcatact ttattgggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000666             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:21949:11981
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000666
VERSION     KCVO01000666.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21949:11981"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72695.1"
                     /translation="DYYCYSTDSSGTHRVF"
     J_segment       390..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          143 c          127 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgctcatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagttg actactactg
      361 ttactcaaca gatagcagtg gtactcatag ggtattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000667             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:13327:2527
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000667
VERSION     KCVO01000667.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13327:2527"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72696.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          142 c          126 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 tccctcggtg tcagtgtccc caggacagac ggccaggatc tcctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaaggcaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagttcagg
      301 gacaatggcc accttgacta tcagtggggc ccaggtggag gatgaaggtg actactactg
      361 ttactcaaca gataacagtg atactcatag gggcttcttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000668             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:22081:8635
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000668
VERSION     KCVO01000668.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22081:8635"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..448
                     /note="immunoglobulin light chain variable region"
     V_region        115..448
     V_segment       115..408
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72697.1"
                     /translation="DYYCSLWDSRLSSRVF"
     J_segment       413..448
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           95 a          156 c          126 g          109 t
ORIGIN      
        1 acatgggaag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctctccttct cactctgctg gttcactgca cagggtcctg gacccagtct
      121 gtgctgacgc agccgccctc agcatctggg gcccccgggc agagggtcac catctcctgc
      181 actgggacca gctccaacat cggggcgaat tattatgttt cctggtacca gcagttccca
      241 ggaacagccc ccaaactcct catctatgaa aataataagc gaccctcagg ggtttctgac
      301 cgattctctg gctccaagtc tggtacctca gcctccctga ccatctctgg actccaatct
      361 gaggatgagg ctgattatta ctgctcacta tgggatagca ggctgagtag tcgggtattc
      421 ggcggaggga cccgactgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01000669             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:16808:15969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000669
VERSION     KCVO01000669.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16808:15969"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72698.1"
                     /translation="DYYCCSYAGRFTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           80 a          158 c          123 g          114 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactgggac
      181 cagcagtgac atcggtgatt atgactttgt ctcctggtac caacagcatc caggcacagc
      241 ccccaaactc ataatttttg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tccggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 cgctgattat tactgctgct catatgcagg caggttcact tttgtgttcg gaagtggcac
      421 cagtttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01000670             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:16440:10167
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000670
VERSION     KCVO01000670.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16440:10167"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72699.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       393..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           94 a          142 c          123 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctacagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaagac gacaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaata gatagtagtg gtagtcatag cgtcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000671             513 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:18361:19279
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000671
VERSION     KCVO01000671.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 513)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 513)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..513
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18361:19279"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    154..475
                     /note="immunoglobulin light chain variable region"
     V_region        154..475
     V_segment       154..441
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <403..>447
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72700.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       442..475
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        476..>513
                     /gene="IGLC"
BASE COUNT          106 a          155 c          144 g          108 t
ORIGIN      
        1 acatgggggc cccatagggc ctgggaagga ataagagaag cctagggagc ccagctgtgc
       61 tgtgggctca ggaggcagag ctctgggtgt ctcaccatgg cctggattcc tctcctactc
      121 cccctcctca ctttctgcac aggctctgca gcctcctatg agctgacaca gccaccctcg
      181 gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagatgc attgccagaa
      241 aaatatgctt attggttcca gcacaagcca ggccagtccc ctgtgctgat catcaatgag
      301 gacagcaaac ggccctctgg gatccctggg agattctctg gctccagctc agggacagtg
      361 gccacattga ctctcagtgg ggcccaggtg gaggatgaag ctgactacta ctgttcctca
      421 acagatagta gtggtaatta tgtattcggc ggagggaccc ggctgaccgt cctaggtcag
      481 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000672             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:19527:5514
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000672
VERSION     KCVO01000672.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:19527:5514"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72701.1"
                     /translation="DYYCSSTDTTGNHRVLF"
     J_segment       380..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           92 a          145 c          115 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcca atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagagg ccaggccagt cccctgtcct gatcatctat gaagacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 ccactggtaa tcatagggtc ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000673             495 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:16752:6996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000673
VERSION     KCVO01000673.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 495)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16752:6996"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    127..456
                     /note="immunoglobulin light chain variable region"
     V_region        127..456
     V_segment       127..420
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <382..>429
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72702.1"
                     /translation="DYFCAVWDDSLSGVLF"
     J_segment       421..456
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>495
                     /gene="IGLC"
BASE COUNT           91 a          156 c          134 g          114 t
ORIGIN      
        1 acatggggga tttgggtgaa gcgcagcttc agctgtgggt acagggcagg actcaggaca
       61 atctccagca tggcctggtt ccctctcctc ctcaccctcc tcactcactg tgcagggtcc
      121 tgggcccagt ctgtgctgac tcagcctccc tcagcgtctg aggccgccag gatgagtgtc
      181 accatctcct gttctggaag cacctccaac atcggaagta acagtgtgtc ctggtacctg
      241 cagctcccgg aaacggctcc caaactcctc atctattata atgatcggcg agcctcaggt
      301 gtctctgacc gattctctgg ctccaagtct ggcccgtcag cctccctggc catcagtggg
      361 ctcgagaccg aagatgaggc tgattatttc tgcgcagtat gggatgatag cctgagcggt
      421 gtgttattcg gaggagggac ccgactgacc gtcctaagtc agcccaaggc tgccccctcg
      481 gtcactctct tcccg
//
LOCUS       KCVO01000674             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:11446:3562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000674
VERSION     KCVO01000674.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11446:3562"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72703.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           82 a          152 c          127 g          114 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtggtt ttgagcgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc ttgatttatg aggtcagtta tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tattgcagct catacgcaag tagtagtact tgggtattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000675             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:9069:16192
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000675
VERSION     KCVO01000675.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9069:16192"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..264
                     /note="immunoglobulin light chain variable region"
     V_region        6..264
     V_segment       6..227
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <189..>236
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72704.1"
                     /translation="DYYCQVWDSSSDHPIF"
     J_segment       230..264
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        265..>302
                     /gene="IGLC"
BASE COUNT           59 a           84 c           90 g           69 t
ORIGIN      
        1 acatgggggg agacatcgtt ggaagtgaat atgttcactg gtatcagcag aagtcagtgc
       61 aggcccctgt ggtggtcatc tattattatt ctgaccggcc ctcagggatc cctgagcgat
      121 tctctggctc caaatcaggg aggatcgcca ccctgaccat cagcggggtc gaggccgggg
      181 atgaggctga ctactactgt caggtgtggg acagtagtag tgatcatccc atcttcggtg
      241 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      301 cg
//
LOCUS       KCVO01000676             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:18832:9438
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000676
VERSION     KCVO01000676.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18832:9438"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72705.1"
                     /translation="DYYCSSTDSRDNHRVF"
     J_segment       376..411
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           92 a          139 c          120 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagatttt ctggctccag ctcagggaca gtggccacgt
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gcagggataa tcatagggta ttcggcggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000677             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:26187:9289
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000677
VERSION     KCVO01000677.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:26187:9289"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..263
                     /note="immunoglobulin light chain variable region"
     V_region        8..263
     V_segment       8..229
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <191..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72706.1"
                     /translation="DYYCQVWDSRTKYIF"
     J_segment       230..263
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        264..>301
                     /gene="IGLC"
BASE COUNT           64 a           90 c           89 g           58 t
ORIGIN      
        1 acatgggggg ggagacacca ttggaagtag aagtgtgcac tggtaccagc agaagccacc
       61 gcaggcccct gccctggtca tatatactga tagcgagcgg ccctcaggga tccctgaccg
      121 attctctggc tccaattcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg
      181 ggatgaggct gactattatt gtcaggtgtg ggacagtagg actaaataca tcttcggtgc
      241 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      301 g
//
LOCUS       KCVO01000678             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:17902:4046
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000678
VERSION     KCVO01000678.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17902:4046"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72707.1"
                     /translation="DYYCSSYTSSSTWIF"
     J_segment       405..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           88 a          155 c          120 g          110 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 acagtgacat tggtggttat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcactaatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca gtagtacttg gattttcggc ggagggaccc
      421 gtctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000679             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:20731:6442
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000679
VERSION     KCVO01000679.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20731:6442"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..404
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72708.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           87 a          160 c          126 g          108 t
ORIGIN      
        1 atgggggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt agtaaaaaca tgtactggta ccagcagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcaggt gtatgacagt actggagtgt tgttcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01000680             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:28884:15099
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000680
VERSION     KCVO01000680.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:28884:15099"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72709.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       392..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           88 a          140 c          138 g           96 t
ORIGIN      
        1 atggggctgg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctta ctgcacagac tctgcggtct cctatgacct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaatgtt
      181 ggaagtgaat atgtgcactg gtaccaacag aaaccagcgc aggcccctgt ggtggtcatc
      241 cattataata gtgaccggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtagtag tgatcattgt gtattgggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000681             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:20084:18638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000681
VERSION     KCVO01000681.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20084:18638"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..400
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72710.1"
                     /translation="DYYCCSYTTSSTFIF"
     J_segment       401..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          152 c          116 g          116 t
ORIGIN      
        1 acatgggggg ggtctcagaa ggcagcgctc tcaggacgtc tccaccatgg cttggactct
       61 gctcctcgtc accctcctca ctcaaggcac aggatcctgg gctcagtctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgatatt gggtattata atactgtgtc ttggtaccaa cagcacccag gcacagcccc
      241 caaagtcatg atttatggtg tcagtaatcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgttgttcat atacaaccag tagtactttc atcttcggtg atgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01000682             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:3655:13128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000682
VERSION     KCVO01000682.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:3655:13128"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72711.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          162 c          125 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acccggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000683             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:12497:2836
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000683
VERSION     KCVO01000683.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12497:2836"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72712.1"
                     /translation="DYYCQVWDSSSDHPIF"
     J_segment       396..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           86 a          145 c          138 g           99 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acaggctctg cggtctccta tgagctgact
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 aacgttggaa gtgaatatgt gcactggtat cagcagaagt cagcgcaggc ccctgtggtg
      241 gtcatctatt attatagtga ccggccctca gggatccctg agcgattctc tggctccaaa
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag tagtagtgat catcccatct tcggtactgg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCVO01000684             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:20318:11072
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000684
VERSION     KCVO01000684.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:20318:11072"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72713.1"
                     /translation="DYYCQVWDSTNDHILF"
     J_segment       395..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          146 c          135 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaga taaatatgta cactggtacc agcagaagcc agcgcgggcc cctgtgttgg
      241 tcatctacta tgatagtgac cggccctcat ggatccctga gcgattctct gggtccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt actaatgatc atatcttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000685             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:12630:14556
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000685
VERSION     KCVO01000685.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:12630:14556"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72714.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           87 a          154 c          123 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagtacccag gcaaagcccc
      241 caaagtcatc atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttcactgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000686             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:17468:18061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000686
VERSION     KCVO01000686.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17468:18061"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72715.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           87 a          156 c          122 g          108 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acaccaccca ggcaaagccc
      241 ccaaactcat gatttatgaa gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca gtagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000687             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:24168:6103
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000687
VERSION     KCVO01000687.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:24168:6103"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72716.1"
                     /translation="DYYCSSTDRSGNHVF"
     J_segment       392..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           92 a          141 c          127 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgaac tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagttcagg
      301 gacagtggcc accttgactg tcagtggggc ccaggtggag gatgaggctg actactactg
      361 ttcctcaaca gatagaagtg gtaatcatgt gttcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000688             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:8563:3272
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000688
VERSION     KCVO01000688.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8563:3272"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72717.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           94 a          159 c          120 g          107 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggtacagaag gcaggactca ggacaatctc cagcatggcc
       61 tggttccctc tcctcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg
      121 ctgactcagc ctccctcagc gtctgaggcc gccaggaaga gtgtcaccat ctcctgttct
      181 ggaagcacct ccaacatcgg aactaatagt gtatcctggt accagcagct cccagaaacg
      241 gctcccaaac tcctcatcta ttataatgat cgacgagcct caggtgtctc tgaccgattc
      301 tctggctcca agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat
      361 gaggctgatt attactgcgc agcatgggat aacagcctga gcggttacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01000689             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:24304:16747
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000689
VERSION     KCVO01000689.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:24304:16747"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72718.1"
                     /translation="DYYCHSLDGSGNDVF"
     J_segment       378..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           88 a          137 c          118 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttactggtt ccagcagaag ccaggccagt cccctgtggt gatcatctat gaggacacca
      241 aacggccctc tgggatccct gagagattct ttggttccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgtcat tcattagatg
      361 gcagtggtaa tgatgttttc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000690             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:11024:13720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000690
VERSION     KCVO01000690.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11024:13720"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72719.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          159 c          119 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcttgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000691             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:10565:14222
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000691
VERSION     KCVO01000691.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:10565:14222"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72720.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           96 a          144 c          123 g           97 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggtaccagca gaaaccaggc cagtccccta tgctgatcat
      241 ctgtgaggac agcaaacggc cctctgggat ccctgaaaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacaacagtg gtcagggctc attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000692             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:11361:18472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000692
VERSION     KCVO01000692.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11361:18472"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72721.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           81 a          153 c          125 g          113 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttttg agcgtgtctc ctggtaccaa cagcccccag gcaaagcccc
      241 caaactcttg atttatgagg tcacttatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattat tgcagctcat acgcaagtag tagtacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000693             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:16532:22220
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000693
VERSION     KCVO01000693.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16532:22220"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..383
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72722.1"
                     /translation="DYYCQVWDSSSDHWVF"
     J_segment       389..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          145 c          137 g           95 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactgcacag gctctgcggt ctcctatgag ctgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggcccggat cacctgtggg ggagacaaca
      181 ttggaagtaa aagtgtgcag tggttccagc agaagccacc gcaggcccct gtattggtca
      241 tttattctga taacgaacgg ccctcaggga tccctgaacg attctctggc tccaactcag
      301 gaagcaccgc caccctgacc atcagcgggg tcgaggccgg gaatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatcatt gggtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000694             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:10101:3083
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000694
VERSION     KCVO01000694.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10101:3083"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72723.1"
                     /translation="DYYCQVWDSSSDVFF"
     J_segment       386..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           86 a          141 c          137 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactgcacag actctgtggt ctcctatgaa ttaactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacagca
      181 ttggaagtag aagtgtgcag tggtaccagc agaagccacc gcaggccctt gtactggtca
      241 tctattctga tagcgaacgg ccctcaggga tccctgagcg attctctggc tccaatttag
      301 ggaacaccgc caccctgacc atcagcggcg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatgtgt tcttcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000695             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:22436:7686
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000695
VERSION     KCVO01000695.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22436:7686"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..420
                     /note="immunoglobulin light chain variable region"
     V_region        101..420
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72724.1"
                     /translation="DYYCHSLDTSGNDVF"
     J_segment       392..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>460
                     /gene="IGLC"
BASE COUNT           90 a          143 c          126 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcact
      181 gccaaaaaaa tttgcttact ggttccagca gaagccaggc cagtcccctg tggcgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 tcattcatta gataccagtg gtaatgatgt tttcggcgga gggacccggc tgaccgtcct
      421 gggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000696             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:20960:10647
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000696
VERSION     KCVO01000696.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20960:10647"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..397
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72725.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       398..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           83 a          161 c          118 g          109 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcactct caggacgtct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 tctccctctg tgtctgggtc tcctggacag tcggtcaccc tttcctgcac tggaaccagc
      181 agtgacattg gtggttataa ccgtgtctcc tggtaccaac accacccagg taaagccccc
      241 aaactcatga tttatgacgt cagtgatcgg ccctcagggg tctctgatcg cttctctggt
      301 tccaagtctg gcaacacggc ctccctgatc atctctgggc tccaggctga ggacgaggct
      361 gattattact gcagctcata cgcaagcact tccacttggc tattcggcgg agggacccgc
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000697             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:11118:19394
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000697
VERSION     KCVO01000697.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11118:19394"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72726.1"
                     /translation="DYHCQVWDSSSDVLF"
     J_segment       385..422
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           85 a          141 c          141 g           93 t
ORIGIN      
        1 acatgggggg gcctcgggaa gcagccttgg cggtgcctca gccatggccg ggacccttct
       61 cctcctcggc ctccttgctc actgcacaga ctctgtggtc tcctatgaat tgactcagcc
      121 acgctcagtg tccgtgtccc caggacagac ggccaggatc acctgtgggg gagacaggat
      181 tggaagtaga agcgtgcagt ggtaccagca gaagccaccg caggcccttg cactggtcat
      241 ctatgctgat agcgaacggc cctcagggat ccctgagcgc ttctctggct ccaatctagg
      301 gaacaccgcc accctgacta ttagcggcgt cgaggccggg gatgaggctg actatcactg
      361 tcaggtgtgg gacagtagta gtgatgtgtt attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000698             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:7088:2259
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000698
VERSION     KCVO01000698.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:7088:2259"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72727.1"
                     /translation="DYYCYSIDSSGNESIF"
     J_segment       391..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           94 a          138 c          125 g          106 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagt tgacacaacc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gggatgcatt
      181 gccaaaaaaa tttgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac agtaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaaggtg actactactg
      361 ttactcaata gatagcagtg gtaatgagag catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000699             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:19036:15938
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000699
VERSION     KCVO01000699.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19036:15938"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72728.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       379..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           91 a          140 c          116 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaagtatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaagacgaca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaatagata
      361 gtagtggtag tcatagcgtc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000700             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:17052:8367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000700
VERSION     KCVO01000700.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17052:8367"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72729.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       391..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          143 c          127 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcagacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccagggggag gatgaagctg actactactg
      361 ttattcaatg gatagcagtg gtactcagag catcttcggt gctgggaccc ggctctccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000701             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:23604:14547
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000701
VERSION     KCVO01000701.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:23604:14547"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72730.1"
                     /translation="DYYCQVWDSSSDHPIF"
     J_segment       395..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          145 c          136 g          100 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtttcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acgttggaag tgaatatgtg cactggtatc agcagaagtc agcgcaggcc cctgtggtgg
      241 tcatctatta ttatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc atcccatctt cggtactggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01000702             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:11537:17198
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000702
VERSION     KCVO01000702.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11537:17198"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72731.1"
                     /translation="DYYCYSSDSSADYWVF"
     J_segment       390..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>464
                     /gene="IGLC"
BASE COUNT           90 a          141 c          129 g          104 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccagaaaa atatgcttat tggttccagc agaagccagg ccagtcccct gtgttgatca
      241 tctatgagga cagcaaacgg ccctctggga tccctgagag attctctggt tccagctcag
      301 ggacagtggc caccttgact atcagtgggg cccaggtgga ggatgaagct gactactact
      361 gttactcatc agatagcagt gctgattatt gggtgttcgg cggagggacc cggctgaccg
      421 tcccaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000703             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:14616:6752
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000703
VERSION     KCVO01000703.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:14616:6752"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72732.1"
                     /translation="DYYCSSYADTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          160 c          120 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcagacac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000704             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:22572:16329
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000704
VERSION     KCVO01000704.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:22572:16329"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..426
                     /note="immunoglobulin light chain variable region"
     V_region        103..426
     V_segment       103..398
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72733.1"
                     /translation="DYFCCSYADTYTFVF"
     J_segment       403..426
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>471
                     /gene="IGLC"
BASE COUNT           82 a          156 c          121 g          112 t
ORIGIN      
        1 acatgggggg gtctcagacg gcagcgctct cgggacatct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 cctcgctcag tgtctgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgacatcg gtggttataa ctttgtctcc tggtaccaac aacatccagg cacagccccc
      241 aaactcatgg tttatgaggt caatcagcgg ccctcagggg tctctgatcg cttctctggc
      301 tcaaagtctg gcaacacggc ctccctgacc gtctccgggg tccaggctga ggacgaggct
      361 gattatttct gctgctcata tgcagacacc tacacttttg ttttcggaag tggcaccagg
      421 ttgaccgtcg tcggtcagcc caaggcttcc cccttggtca ctctgttccc g
//
LOCUS       KCVO01000705             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:14324:7362
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000705
VERSION     KCVO01000705.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14324:7362"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72734.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           92 a          144 c          115 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gacgacagca
      241 aacgcccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcat tggggcccag gtggaggatg aagctgacta ccactgtttc tcaacagata
      361 gcagtggtaa tcataggggc ttattcggag gagggacccg actgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000706             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:25876:19377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000706
VERSION     KCVO01000706.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:25876:19377"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..431
                     /note="immunoglobulin light chain variable region"
     V_region        86..431
     V_segment       86..395
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72735.1"
                     /translation="DYHCMIRHNNAYIF"
     J_segment       396..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           93 a          156 c          109 g          111 t
ORIGIN      
        1 acatggggga aaagaggctg tgtccaccat ggcctggact cctctcctcc tcctgctcct
       61 ctctcactgc acaggttccc tctcgcagcc tgtgctgact cagccaacct ccctctcagc
      121 atctcctgga acatcagcca gactcacctg caccttgcgc agtggcatca gtgttggtag
      181 ttacgggatt ttctggtacc aacagaagcc agggagtcct ccccggtatc ttctgaacta
      241 ccacacagac tcagagaagc accagggatc tggagtcccc agccgcttct ctggatccaa
      301 ggatacttcg gccaatgcag gctttttact catctctggg ctccagtctg aggatgaggc
      361 tgactatcac tgtatgattc ggcacaacaa tgcttacatc ttcggtgctg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000707             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:23048:4509
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000707
VERSION     KCVO01000707.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:23048:4509"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72736.1"
                     /translation="DYHCFSTDSSGNHRGIF"
     J_segment       382..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           91 a          143 c          119 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gacgacagca
      241 aacggccctc tgggatccct gggagagtct ctggctccag ctcagggaca gtggccacct
      301 tgactatcat tggggcccag gtggaggatg aagctgacta ccactgtttc tcaacagata
      361 gcagtggtaa tcataggggc atattcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000708             333 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:24675:13983
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000708
VERSION     KCVO01000708.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 333)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:24675:13983"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    73..295
                     /note="immunoglobulin light chain variable region"
     V_region        73..295
     V_segment       73..255
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <217..>267
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72737.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       259..295
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        296..>333
                     /gene="IGLC"
BASE COUNT           67 a          103 c           88 g           75 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacagcagaa ggcaggccag tcccctgtgt tgatcatcta tgaggacagc
      121 aaacggccct ctgggatccc tgagagattc tctggctcca gttcagggac aatggccacc
      181 ttgactatca gtggggccca ggtggaggat gaagctgact actactgtta ctcaacagat
      241 aacagtgata ctcatagggg cttcttcgga ggagggaccc ggctgaccgt cctaggtcag
      301 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000709             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:3512:18823
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000709
VERSION     KCVO01000709.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:3512:18823"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..439
                     /note="immunoglobulin light chain variable region"
     V_region        91..439
     V_segment       91..399
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72738.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       402..439
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           94 a          155 c          120 g          108 t
ORIGIN      
        1 acatgggggg tggggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcc aagcctatgc tgactcagcc ggcctccctc
      121 tcagcatctc ctggagcatc agccagtctc acatgcacct tcagcggtgg catcaatgtt
      181 gctggctacc acatacactg gtaccagcag aagccaggga gtcctccccg gtatcttctg
      241 agatacaaat cagactcaga taagggccag ggctctggag tccccagccg cttctctgga
      301 tccaaagatg gttcagcgaa cacagggatt ttacgcatct ctgggctcca gtctgaggat
      361 gaggctgact attactgtgc cattggacac agcagcggtg attacatctt cggtgctggg
      421 acccggctca ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01000710             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:9071:11457
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000710
VERSION     KCVO01000710.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:9071:11457"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72739.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          153 c          122 g          111 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgatttt aaccgtgtct cctggtacca acaataccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaatacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca gtagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000711             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:6526:11965
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000711
VERSION     KCVO01000711.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6526:11965"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72740.1"
                     /translation="DYYCYSTVSSGNGRIF"
     J_segment       378..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           90 a          140 c          118 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgtca aaaaaatatg
      181 cttattggtt ccagcagaag ccgggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagactct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagtta
      361 gcagtggtaa tggtaggatc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000712             494 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:25394:6955
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000712
VERSION     KCVO01000712.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 494)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:25394:6955"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..456
                     /note="immunoglobulin light chain variable region"
     V_region        123..456
     V_segment       123..416
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72741.1"
                     /translation="DYYCLSYDSSLTAHYIF"
     J_segment       419..456
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>494
                     /gene="IGLC"
BASE COUNT           97 a          166 c          121 g          110 t
ORIGIN      
        1 acatgggggg ggaagctctg cttcagctgt gggcacagga ggcagcactc aggacagtct
       61 ccagcatggc ctcgtctcct ctcctcctca cccttctcat tcactgcaca gggtcctggg
      121 cccagtctgt gctgacacag ccaccctcag tatctggggc cccagggcag agggtcacca
      181 tctcgtgcac tgggagcagc tccagcattg gaggtgatta tgtatcctgg taccaacagc
      241 tcccaggaac gacccccaaa ctcctcatct atcaaaataa taagcgaccc tcaggggttt
      301 ctgaccgatt ctctggctcc aagtctggta cctcagcctc cctgaccatc actgggctcc
      361 agactgagga tgaggctgat tactactgcc tgtcctatga cagcagtctg actgctcatt
      421 acatcttcgg tcctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg
      481 tcactctgtt cccg
//
LOCUS       KCVO01000713             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:25202:7743
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000713
VERSION     KCVO01000713.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:25202:7743"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72742.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          145 c          124 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctctgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gaaatgcatt
      181 gccaaaatac tatgcttatt ggttccagca gaagccaggc cagtcccctg tggcgatcat
      241 ctatgaggac agcaaacggc cctctgcgat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtagag gatgaggctg actactactg
      361 ttactcaaca gatagcagtg gtactaatgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000714             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:26150:6708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000714
VERSION     KCVO01000714.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:26150:6708"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72743.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       397..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          142 c          139 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagactctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaaacc agcgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgcctccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgtgtatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000715             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:17648:6760
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000715
VERSION     KCVO01000715.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17648:6760"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72744.1"
                     /translation="DYYCGAWDSSLSGRLF"
     J_segment       409..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          155 c          130 g          107 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gtgtctgggg accccgggca gagggtcacc atctcgtgca
      181 ctgggagcag ctccaacatt ggaggttatt ttgtatactg gtaccagcag ttcccaggaa
      241 cagcccccaa actcctcatc tatgacaata ataagcgacc ctcagggatt tctgaccgat
      301 tctctggctc caagtctggt acctcagcct ccctgaccat cactgggctc cagcctgggg
      361 atgaggctga ttattactgc ggagcatggg atagcagcct gagtggtcgc ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000716             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:19701:17409
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000716
VERSION     KCVO01000716.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19701:17409"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72745.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           89 a          142 c          117 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatttg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gcagtggtaa tcatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000717             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:20275:15656
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000717
VERSION     KCVO01000717.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20275:15656"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72746.1"
                     /translation="DYYCQSADDSYNYIF"
     J_segment       404..440
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           85 a          161 c          124 g          108 t
ORIGIN      
        1 acatggggct ggctgtgact cagaaagcag agcctggggc gtctccacca tggcctgggc
       61 tccactcctc ctcaccctcc tcgctcactg cacagggtct tgggctgagg ttgtgttcac
      121 tcagccccat tctgtgtcgg ggtctccggg gcagacggtc accatctcct gcacccgcag
      181 cagtggcagc attgacagtg aatatgtgcg gtgttaccag cagcgcccgg gcaatgcccc
      241 caccacagtg atttacaaag ataaccaaag accctctggg gtccctgatc ggttctctgg
      301 ctccattgac agctcctcca actctgcctc cctcgccatc tctgggctga agtctgagga
      361 cgaggctgac tactactgtc agtctgctga tgacagctac aattacatct tcggtgctgg
      421 gtcccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCVO01000718             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:18571:10999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000718
VERSION     KCVO01000718.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18571:10999"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72747.1"
                     /translation="DYYCYSTISSGNDRIF"
     J_segment       392..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           95 a          138 c          123 g          107 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gtcaaaaaaa tatgtttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggtt ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca attagtagtg gtaatgatag gatcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000719             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:13583:14804
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000719
VERSION     KCVO01000719.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13583:14804"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..384
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72748.1"
                     /translation="DYYCQVWDSITAQWVF"
     J_segment       393..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           84 a          148 c          140 g           95 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca caggctttgc ggtctcctat gagctgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggcccg gatcacctgt gggggagaca
      181 acattggaag taaaagtgtg cagtggttcc agcagaggcc accgcaggcc cctgtgctgg
      241 tcatttatac tgataaccag cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cgggaatgag gctgactatt
      361 attgtcaggt gtgggacagt attactgctc agtgggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000720             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:23302:16542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000720
VERSION     KCVO01000720.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:23302:16542"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..430
                     /note="immunoglobulin light chain variable region"
     V_region        85..430
     V_segment       85..393
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72749.1"
                     /translation="DYYCQVYDGSAWVF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           86 a          154 c          121 g          107 t
ORIGIN      
        1 acatggggag aggtagctgt gtccaccatg gccctgactc ctctcctcct cctgctcctc
       61 tctcactgca caggttccct ctcccagcct gtgctgactc agccaccctc cctgtctgca
      121 tccccgggag catcggccag actcccctgc accctgagaa gtgacctcag tgttggtagt
      181 aaaaacatgt actggtacca gcagaagcca gggagcgctc ccaggttatt cctctactac
      241 ttctccgact cagacaagca gctgggacct ggggtcccca atcgagtctc tggctccaag
      301 gagacgtcaa gtaatgcagc gtttttgatc atctctgggc tccagcctga ggacgaggcc
      361 gattattact gtcaggtgta tgacggtagt gcttgggtat tcggcggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000721             433 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:18950:14392
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000721
VERSION     KCVO01000721.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 433)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:18950:14392"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    65..395
                     /note="immunoglobulin light chain variable region"
     V_region        65..395
     V_segment       65..359
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <323..>367
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72750.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       360..395
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        396..>433
                     /gene="IGLC"
BASE COUNT           83 a          139 c          116 g           95 t
ORIGIN      
        1 acatggggag ccccgctgtc cagggaagca gaagcctctg agcccaggcc caggatcctg
       61 ggctcaggct gccctgactc agtctccctc tgtgtctggg tctcctggac agtcggtcac
      121 catttcctgc actggaacca gcagtgacat tggtgattat aaccgtgtct cctggtacca
      181 acagcaccca ggcaaagccc ccaaactcat gatttatgag gtcagtgatc ggccctcagg
      241 ggtctctgat cgcttctctg gttccaagtc tggcaacacg gcctccctga tcatctctgg
      301 gctccaggct gaggacgagg ctgattatta ctgcagctca tacacaagca gtagcacttg
      361 ggtattcggc ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt
      421 cactctcttc ccg
//
LOCUS       KCVO01000722             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:21088:5043
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000722
VERSION     KCVO01000722.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21088:5043"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72751.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          151 c          124 g          114 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttttg agcgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcttg atttatgagg tcagttatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct gccaacacgg cctccctgat catctctggg ctccaggttg aggacgaggc
      361 tgattattat tgcagctcat acacaagtag tagtacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000723             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:20670:7754
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000723
VERSION     KCVO01000723.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20670:7754"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..372
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72752.1"
                     /translation="DYYCYSMDSSTYLGFF"
     J_segment       374..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           91 a          142 c          114 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatacg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtatt gatcatctat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaatggata
      361 gcagtactta tcttggcttc ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000724             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:14930:16053
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000724
VERSION     KCVO01000724.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14930:16053"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72753.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          161 c          119 g          106 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccccgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000725             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:14306:13334
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000725
VERSION     KCVO01000725.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14306:13334"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72754.1"
                     /translation="EYYCSSFAATYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          154 c          116 g          114 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccaa
      181 cagtgacatc ggtaattata actatgtctc ctggtaccaa caacatccag gcacagcccc
      241 caaactcatg atttatgagg tcagtgagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catttctgga ctccaggctg aggacgaggc
      361 tgaatattac tgtagttctt ttgcagccac ttacactttt gtgttcggaa gtggcaccaa
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01000726             413 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:23220:17797
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000726
VERSION     KCVO01000726.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 413)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:23220:17797"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..375
                     /note="immunoglobulin light chain variable region"
     V_region        85..375
     V_segment       85..335
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <303..>347
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72755.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       339..375
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        376..>413
                     /gene="IGLC"
BASE COUNT           88 a          127 c          112 g           86 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccat cctcactttc tgcacagtgt ccccaggaca gacggccagg atcacctgct
      121 ctggagatgc attgccagaa aaatatgctt attggtacca gcagaaacca ggccagtccc
      181 ctatgctgat catctgtgag gacagcaaac ggccctctgg gatccctgaa agattctctg
      241 gctccagctc agggacagtg gccaccttga ctatcactgg ggcccaggtg gaggatgaag
      301 ctgactacta ctgttactca gcagacaaca gtggtcaggg ctcattcgga ggagggaccc
      361 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000727             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:13101:13734
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000727
VERSION     KCVO01000727.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13101:13734"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..258
                     /note="immunoglobulin light chain variable region"
     V_region        8..258
     V_segment       8..221
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <183..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72756.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       226..258
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        259..>296
                     /gene="IGLC"
BASE COUNT           64 a           81 c           89 g           62 t
ORIGIN      
        1 acatgggcaa tgttggaagt gaatatgtgc actggtacca acagaaacca gcgcaggccc
       61 ctgtggtggt catccattat aatagtgacc ggccctcagg gatccctgag cgattctctg
      121 gctccaaatc agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg
      181 ctgactatta ctgtcaggtg tgggacagta gtagtgatca ttgtgtattg ggaggaggga
      241 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000728             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:10333:21977
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000728
VERSION     KCVO01000728.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10333:21977"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72757.1"
                     /translation="DYYCQVWDSSTNHILF"
     J_segment       394..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          145 c          136 g           97 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg cttactgcac aggctctgtg gtctcctatg agctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 ccttggagat aaatatgtac actggtacca gcagaagcca gcgcgggccc ctgtgctggt
      241 catctactat gatagtgacc ggccctcatg gatccctgag cgattctctg ggtccaaatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta gtactaatca tatcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000729             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:21186:11063
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000729
VERSION     KCVO01000729.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:21186:11063"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72758.1"
                     /translation="EYYCSSYAGSYTLVF"
     J_segment       404..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           81 a          160 c          123 g          111 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagttggtc accatctcct gcattggaac
      181 cagcagtgac atcggtgctt atgactatgt ctcctggtac caacagcatc caggcacagc
      241 ccccaaactc atgatttttg aggtcagtga gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctgccaaca cggcccccct gaccatctct gggctccagg ctgaggacga
      361 ggctgagtat tactgttcct catatgcagg cagctacact ctcgtgttcg gaagtggcac
      421 caagttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01000730             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:11115:8699
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000730
VERSION     KCVO01000730.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11115:8699"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72759.1"
                     /translation="EYYCSSYADIYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          162 c          119 g          109 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tggcctcagg ctgccctgac
      121 tcagcctcgg tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcacgggcac
      181 cagcagtgac atcggtggtt acaactttgt ctcctggtac caacaccatc cagacacagc
      241 ccccaaactc ctgatttatg aggtcactca gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgaatat tactgcagtt catatgcaga catctacaca tttgtgttcg gaagtggcac
      421 caagttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01000731             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:18288:11453
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000731
VERSION     KCVO01000731.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18288:11453"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72760.1"
                     /translation="DYYCHLYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          161 c          123 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gtctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcact tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000732             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:8229:15559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000732
VERSION     KCVO01000732.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8229:15559"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72761.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           94 a          142 c          124 g          105 t
ORIGIN      
        1 acatggggtg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactccccc tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagact
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatct cctgctctgg agatgcattg
      181 ccaaaaaaat ttgcttcttg gttccagcag aaggcaggcc agtcccctgt gctgatcatc
      241 tatgaggaca gcaaacggcc ctctgggatc cctgagagat tctctggctc cagttcaggg
      301 acaatggcca ccttgactat cagtggggcc caggtggagg atgaagctga ctactactgt
      361 tactcaacag ataacagtga tactcatagg ggcttcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000733             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:26997:6413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000733
VERSION     KCVO01000733.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:26997:6413"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72762.1"
                     /translation="DYYCQVWDSSSDHPIF"
     J_segment       391..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           85 a          143 c          137 g           98 t
ORIGIN      
        1 acatgggggg gcctcgggaa gcagccttgg cggtgcctca gccatggccg ggacccttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggtc tcctatgagc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacgt
      181 tggaagtgaa tatgtgcact ggtatcagca gaagtcagcg caggcccctg tggtggtcat
      241 ctattattat agtgaccggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtgatcatcc catcttcggt actgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000734             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:5038:11292
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000734
VERSION     KCVO01000734.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:5038:11292"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72763.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           91 a          144 c          116 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gacgacagca
      241 aacgcccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcat tggggcccag gtggaggatg aagctgacta ccactgtttc tcaacagata
      361 gcagtggtaa tcataggggc ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000735             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:12742:6386
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000735
VERSION     KCVO01000735.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12742:6386"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..422
                     /note="immunoglobulin light chain variable region"
     V_region        104..422
     V_segment       104..385
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72764.1"
                     /translation="DYWCQSTDSSGFIF"
     J_segment       388..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           99 a          133 c          125 g          103 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 accaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aattatggtc agtggttcca gcagaagccg ggccaggccc ctgtgttggt
      241 gatatataaa gacagtgaga ggccctcagg gatccctggg cgattctcta gctccagttc
      301 agggacatca attaccttga ccatcagtgg ggcccaggca gaggatgagg ctgactattg
      361 gtgtcaatca acagacagca gtggtttcat cttcggtgct gggacccgac tcaccgtcct
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01000736             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:26307:12865
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000736
VERSION     KCVO01000736.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:26307:12865"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72765.1"
                     /translation="DYYCYSTDSSGNGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           96 a          142 c          126 g          100 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccatcctc actttctgca caggctctgc agcctccaat gagctgacac
      121 agccaccctc gttgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg
      181 cattgccaga aaaatttgct tattggtacc agcagaaacc aggccagtcc cctgtgctga
      241 tcatgtatga ggacagcaaa cggccctctg ggatccctga gagattctct ggctccacct
      301 cagggacagt ggccaccttg actatcagtg gggcccaggt ggaggatgaa gctgactact
      361 actgttactc aacagacagc agtggtaatg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000737             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:5915:7267
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000737
VERSION     KCVO01000737.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:5915:7267"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72766.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       378..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           88 a          142 c          118 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gggagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagaca
      361 gtagtggtaa ttatgtcttc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000738             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:23593:21847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000738
VERSION     KCVO01000738.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:23593:21847"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..439
                     /note="immunoglobulin light chain variable region"
     V_region        112..439
     V_segment       112..405
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72767.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       407..439
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>480
                     /gene="IGLC"
BASE COUNT           91 a          153 c          130 g          106 t
ORIGIN      
        1 acatgggggg cttcagctgt gggcacagga ggcagcactc aggacagtct ccagcatggc
       61 ctggtctcct ctcctcctca ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggac cccgggcaga gggtcaccat ctcgtgcact
      181 gggagcagct ccaacattgg aggttatttt gtatactggt accagcagtt cccaggaaca
      241 gcccccaaac tcctcatcta tgacaataat aagcgaccct cagggatttc tgaccgattc
      301 tctggctcca agtctggtac ctcagcctcc ctgaccatca ctgggctcca gcctggggat
      361 gaggctgatt attactgcgg agcatgggat agtagcctga gtgctcgctt attcggagga
      421 gggacccggc tgaccgtcca aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000739             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:8471:6990
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000739
VERSION     KCVO01000739.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8471:6990"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72768.1"
                     /translation="DYYCSSYADTYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           79 a          162 c          118 g          113 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggcaccag
      181 cagtgacatc ggtggttata actttgtctc ctggtaccaa caccatccag gcacagcccc
      241 caaactcgtt atttatgagg tcactcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacgcgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgctcctcat atgcagacac ttacactttt gtgttcggaa gtggccccaa
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01000740             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:19693:7624
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000740
VERSION     KCVO01000740.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:19693:7624"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72769.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          156 c          129 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cgggagtaac agtgtgtcct ggtacctgca gctcccagaa
      241 acggctccca aactcctcat ctattataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cccgtcagcc tccctggcca tcagtgggct cgagaccgaa
      361 gatgaggctg attattactg cgcagtatgg gatgacagcc tgagcggtgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01000741             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:11605:16718
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000741
VERSION     KCVO01000741.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:11605:16718"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72770.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          160 c          125 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc aaaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000742             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:15099:5777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000742
VERSION     KCVO01000742.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15099:5777"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..400
                     /gene="IGLV8-111"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72771.1"
                     /translation="DYYCSLYMATGFVFF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          151 c          123 g          113 t
ORIGIN      
        1 acatggggga gaagcctgag agcacttggc cttcataagt gtccccacca tggcctggat
       61 gatgcttctc ctcggactcc ttgcttatgg ctcaggagtg gattctgaga ctgtggtgac
      121 ccaggagcca tcgttgtcag tgtcccctgg aggaacagtc acactcacct gtggcctgaa
      181 ctctggctca gtctctatca gtaattaccc cagctggtac cagcagaccc caggccaggc
      241 tccacgcatg ctcatcttca gcacaaacag tcgcccttct ggggtccctg atcgcttctc
      301 tggctccatc cgtgggaaca aagctgccct caccatcacg ggggctcagg cagacgatga
      361 ctctgattat tactgttcgc tctacatggc tactggcttt gtgttcttcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000743             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:24205:6697
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000743
VERSION     KCVO01000743.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:24205:6697"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..423
                     /note="immunoglobulin light chain variable region"
     V_region        101..423
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72772.1"
                     /translation="DYYCQVWDFSGDHNIF"
     J_segment       390..423
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>463
                     /gene="IGLC"
BASE COUNT           90 a          148 c          128 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatgacct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctctgaac tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccagaatc acctgtggga gagacaacat
      181 tggaaataaa aatgtgcact ggtaccagca gcggccaccg cgggcccctg tactggtcat
      241 ctattatgat accgagcggc cctcagggat ccctgagcga ttctctggct ccacatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gactttagtg gtgatcataa catcttcgat gctgggaccc ggctcaccgt
      421 cctcggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000744             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:19755:9182
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000744
VERSION     KCVO01000744.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:19755:9182"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72773.1"
                     /translation="EYYCSSFAATYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          155 c          116 g          116 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 caacagtgac atcggtaatt ataactatgt ctcctggtac caacaacatc caggcacagc
      241 ccccaaactc atgatttatg aggtcagtga gcggccctca tgggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatttct ggactccagg ctgaggacga
      361 ggctgaatat tactgtagtt cttttgcagc cacttacact tttgtgttcg gaagtggcac
      421 caagttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01000745             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:25046:6693
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000745
VERSION     KCVO01000745.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:25046:6693"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72774.1"
                     /translation="DYYCQVWDSITDHSIF"
     J_segment       395..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          149 c          133 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagtctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggggaca
      181 acattggaac tgaatatgtg cactggtacc agcagaagcc accgcaggcc cctgtggtgg
      241 tcatctatta taatactgac cggccctcag ggatccctga gcgattctca ggctccaaat
      301 cagggaacac cggcaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt attactgatc attccatctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01000746             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:23115:12285
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000746
VERSION     KCVO01000746.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:23115:12285"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72775.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          140 c          141 g           94 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcccatgag ctgactcagg
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaatg
      181 ttggaagtga atatgtgcac tggtaccaac agaagccacc gcaggcccct gtggtggtca
      241 tccattataa tagtgaccgg ccctcaggga tccctgagcg aatgtctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatcata gtttattggg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000747             321 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:11368:12669
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000747
VERSION     KCVO01000747.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 321)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11368:12669"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..283
                     /note="immunoglobulin light chain variable region"
     V_region        9..283
     V_segment       9..246
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <208..>255
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72776.1"
                     /translation="DYYCQVWDSSSDHVLF"
     J_segment       249..283
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        284..>321
                     /gene="IGLC"
BASE COUNT           67 a           89 c           99 g           66 t
ORIGIN      
        1 acatgggcgg ccaggatcac ctgtggggga gacaaccttg gagatgaata tgtacactgg
       61 taccagcaga agccagcgcg ggcccctgtg ttggtcatct attacgatag tgaccggccc
      121 tcatggatcc ctgagcgatt ctctgggtcc aaatcaggga aaaccgccac cctgaccatc
      181 agcggggtcg aggccgggga tgaggctgac tattactgtc aggtgtggga cagtagtagt
      241 gatcatgtct tattcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc
      301 ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000748             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:12205:10247
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000748
VERSION     KCVO01000748.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:12205:10247"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72777.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       404..438
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           83 a          158 c          121 g          114 t
ORIGIN      
        1 acatgggggg ctggggtctc agacggcagc gctctcggga catctccacc atggcctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccctga
      121 ctcagcctcg ctcagtgtct gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga catcggtact tataactatg tctcctggta ccaacagcat ccaggcacag
      241 cccccaaact catgattttt gaggtcagtg agcggccctc aggggtctct gatcgcttct
      301 ctggctccaa gtctgccaac acggcctccc tgaccatctc tgggctccag gctgaggacg
      361 aggctgatta ttactgttgc tcatatgcag acacctacac ttttgtgttt ggaggtggca
      421 ccagattgac cgtcctcggt cagcccaagg cttccccctt ggtcactctg ttcccg
//
LOCUS       KCVO01000749             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:20345:4419
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000749
VERSION     KCVO01000749.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20345:4419"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72778.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       379..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           91 a          140 c          117 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgcccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaagtatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaagacgaca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aaggtgacta ctactgttac tcaatagaca
      361 gtagtggtag tcatagcgtc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000750             507 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:5054:8609
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000750
VERSION     KCVO01000750.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 507)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 507)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..507
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5054:8609"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    142..468
                     /note="immunoglobulin light chain variable region"
     V_region        142..468
     V_segment       142..437
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <400..>441
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72779.1"
                     /translation="DYFCSSYTGSITLF"
     J_segment       438..468
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        469..>507
                     /gene="IGLC"
BASE COUNT           97 a          165 c          133 g          112 t
ORIGIN      
        1 acatggggag aggagataac acagggctgg gggcaggccc agtgctgggg tctcaggagg
       61 cagcgctctc aggacgtctc caccatggtc tgggctctgc tcctcctcac cctcctcact
      121 cagggcacag gatcctgggc tcaggctgcc ctgactcagc ctccctctgt gtctgggtct
      181 cctggacagt cggtcaccat ctcctgcact ggaaccagca gtgacatcgg tggttataac
      241 tatgtctcct ggtaccaacg acacccaggc aaagccccca aactcatgat ttatgatgtc
      301 aataagcggc cctcaggggt ctctgatcgc ttctctggct ccaaatctgg caacacggcc
      361 tccctgacca tctctgggct ccagtctgag gatgaggctg attatttctg cagctcatat
      421 acaggcagca tcactttatt cggaggaggg acccggctga ccgtcctacg tcagcccaag
      481 gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000751             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:18052:16576
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000751
VERSION     KCVO01000751.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18052:16576"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72780.1"
                     /translation="DYYCQSYDSRLSGHVF"
     J_segment       418..450
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           87 a          155 c          134 g          112 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct ggcgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccgtct
      181 cctgcactgg gagcagctcc aactttggag gttattatgt gcagtggtac cagcaacttc
      241 caggaacggc ccccaaactc ctcatctatg aaaataataa gcgcccctca ggggtttctg
      301 atcgattctg tggctcccag tctggttcct ccgcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag caggttgagt ggtcatgtat
      421 tcggaggagg gacccgggtg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCVO01000752             415 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:12851:18572
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000752
VERSION     KCVO01000752.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 415)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12851:18572"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..377
                     /note="immunoglobulin light chain variable region"
     V_region        87..377
     V_segment       87..340
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>349
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72781.1"
                     /translation="DYYCYSTDSSGNALF"
     J_segment       343..377
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        378..>415
                     /gene="IGLC"
BASE COUNT           87 a          125 c          113 g           90 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagt gtccccagga cagacggcca ggatcacctg
      121 ctctggagat gcattgccag aaaaatttgc ttattggtac cagcagaaac caggccagtc
      181 ccctgtgctg atcatgtatg aggacagcaa acggccctct gggatccctg agagattctc
      241 tggctccacc tcagggacag tggccacctt gactatcagt ggggcccagg tggaggatga
      301 agctgactac tactgttact caacagacag cagtggtaat gccttattcg gaggagggac
      361 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000753             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:23483:17592
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000753
VERSION     KCVO01000753.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:23483:17592"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..401
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72782.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       402..436
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           82 a          159 c          123 g          110 t
ORIGIN      
        1 acatgggggg ggggtctcag acggcagcgc tctcgggaca tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagcctcgct cagtgtctgg gtctcctggc cagtcggtca ccatctcctg cactggaacc
      181 agcagtgaca tcgggactta caactatgtc tcctggtacc aacagcatcc aggcacagcc
      241 cccaaactca cgatttttga ggtcagtgag cggccctcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccaggc tgaggacgag
      361 gctgattatt actgttgctc atatgcagac acctacactt ttgtgtttgg aggtggcacc
      421 agattgaccg tcctcggtca gcccaaggct tcccccttgg tcactctgtt cccg
//
LOCUS       KCVO01000754             330 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:19133:18824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000754
VERSION     KCVO01000754.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 330)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 330)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..330
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19133:18824"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    73..292
                     /note="immunoglobulin light chain variable region"
     V_region        73..292
     V_segment       73..254
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <217..>264
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72783.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       260..292
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        293..>330
                     /gene="IGLC"
BASE COUNT           68 a          100 c           87 g           75 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacagcagaa gccaggccag tcccctgtgt tgatcatcta tgaggacaac
      121 aaacggccct ctgggattcc tgagagattc tctggctcca gctcagggac agtggccacc
      181 ttgactatca gtggggccca ggtggaggat gaaggtgact actactgtta ctcaagagat
      241 agtagtgaaa atcaaagcgt cttcggtgct gggacccggc tcagcgtcct aggtcagccc
      301 aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01000755             490 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:2785:10534
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000755
VERSION     KCVO01000755.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 490)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:2785:10534"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    128..452
                     /note="immunoglobulin light chain variable region"
     V_region        128..452
     V_segment       128..415
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>424
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72784.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       420..452
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        453..>490
                     /gene="IGLC"
BASE COUNT           99 a          148 c          135 g          108 t
ORIGIN      
        1 acatggggga gaagcctagg gagcccagct gtgctgtggg ctcaggaggc agagctctgg
       61 gtgtctcacc atggcctgga ttcctctcct actccccctc ctcactttct gcacaggctc
      121 tgcagcctcc tatgagctga cacagccacc ctcggtgtca gtgtccccag gacagacggc
      181 caggatcacc tgctctggag atgcattgcc aaaaaagtat gcttattggt tccagcagaa
      241 gccaggccag tcccctgtgt tgatcatcta tgaagacgac aaacggccct ctgggatccc
      301 tgagagattc tctggctcca gctcagggac agtggccacc ttgactatca gtggggccca
      361 ggtggaggat gaaggtgact actactgtta ctcaatagac agtagtggta gtcatagcgt
      421 cttcggtgct gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac
      481 tctgttcccg
//
LOCUS       KCVO01000756             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:18873:5439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000756
VERSION     KCVO01000756.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:18873:5439"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72785.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          144 c          125 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctctgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gaaatgcatt
      181 gccagaatac tatgcttatt ggttccagca gaagccaggc cagtcccctg tggcgatcat
      241 ctatgaggac aacaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtagag gatgaggctg actactactg
      361 ttactcaaca gatagcagtg gtactaatgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000757             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:10393:6953
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000757
VERSION     KCVO01000757.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:10393:6953"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72786.1"
                     /translation="DYYCGAWDSSLTAVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          159 c          124 g          112 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctctgctgac gcagccgccc tcagtgtctg gggaccccgg gcagagggtc accatctcgt
      181 gcactgggag cagctccaac attggacatt attatcttta tttctaccag cagttcccag
      241 gaacagcccc caaactcctc atgtatgaca ataataagcg accctcaggg atttctgacc
      301 gattctctgg ctccaagtct ggtatctcag cctccctgac catcactggg ctccagcctg
      361 gggatgagac tgattattac tgcggcgcct gggatagcag cctgactgct gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01000758             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:19126:7535
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000758
VERSION     KCVO01000758.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19126:7535"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..389
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72787.1"
                     /translation="DYYCQVWDSSSNHWVF"
     J_segment       394..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           87 a          148 c          139 g           94 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgctcactgc acagtctctg cggtctccta tgaactgact
      121 cagccacgct ctgtgtccgt gtccccagga cagacggccc ggatcacctg tgggggagac
      181 aacatcggaa gtaaaagtgt gcagtggttc cagcagaagc caccgcaggc ccctgtgctg
      241 gtcatttata ctgatagcga acggccctca gggatccctg agcgattctc tggctccaac
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccgggaatga ggctgactat
      361 tattgtcagg tgtgggacag tagtagtaat cactgggtat tcggcggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000759             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:15812:15275
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000759
VERSION     KCVO01000759.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:15812:15275"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72788.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           96 a          143 c          124 g           97 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcgtcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggtaccagca gaaaccaggc cagtccccta tgctgatcat
      241 ctgtgaggac agcaaacggc cctctgggat ccctgaaaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacaacagtg gtcagggctc attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000760             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:8291:9140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000760
VERSION     KCVO01000760.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:8291:9140"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..444
                     /note="immunoglobulin light chain variable region"
     V_region        115..444
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72789.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       409..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>483
                     /gene="IGLC"
BASE COUNT           92 a          155 c          128 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagtaac agtgtgtcct ggtacctgca gctcccagaa
      241 acggctccca agctcctcat ctattataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cccgtcagcc tccctggcca tcagtgggct cgagaccgaa
      361 gatgaggctg attattactg cgcagtatgg gatgatagcc tgagcggtgt gttattcgga
      421 ggagggaccc gactgaccgt cctaagtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01000761             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:14169:10653
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000761
VERSION     KCVO01000761.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14169:10653"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72790.1"
                     /translation="DYYCYSTDNSGNHIF"
     J_segment       374..408
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           92 a          144 c          111 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aggctgacta ctactgttac tcaacagata
      361 acagtggtaa tcacatcttc gctgctggga cccggctcac cgtcctaggt cagcccaagg
      421 cttcccccac ggtcactctg ttcccg
//
LOCUS       KCVO01000762             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:15349:13275
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000762
VERSION     KCVO01000762.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15349:13275"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72791.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       399..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          147 c          134 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaga taaatatcta cactggtacc accagaagcc agcgcaggcc cctgtgctgg
      241 tcatctacta tgatagtgac cggccctcat ggatccctga gcgattctct gggtccaagt
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt aataatgatc atatcttttt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000763             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:19999:7300
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000763
VERSION     KCVO01000763.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:19999:7300"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72792.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       406..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           94 a          158 c          120 g          108 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggtacagaag gcaggactca ggacaatctc cagcatggcc
       61 tggttccctc tcctcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg
      121 ctgactcagc ctccctcagc gtctgaggcc gccaggaaga gtgtcaccat ctcctgttct
      181 ggaagcacct ccaacatcgg aactaatagt gtatcctggt accagcagct cccagaaacg
      241 gctcccaaac tcctcatcta ttataatgat cgacgagcct caggtgtctc tgaccgattc
      301 tctggctcca agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat
      361 gaggctgatt attactgcgc agcatgggat aacagtctga gcggttacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01000764             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:25743:7700
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000764
VERSION     KCVO01000764.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:25743:7700"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    68..392
                     /note="immunoglobulin light chain variable region"
     V_region        68..392
     V_segment       68..355
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <317..>364
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72793.1"
                     /translation="DYYCYSTDSSTNHGLF"
     J_segment       356..392
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        393..>430
                     /gene="IGLC"
BASE COUNT           93 a          136 c          108 g           93 t
ORIGIN      
        1 acatgggacc atggcctgga ttcctctcct actccccctc ctcactttct gcacaggctc
       61 tgcagcctcc tatgagctga cacagccacc ctcggtgtca gtgtccccag gacagacggc
      121 caggatcacc tgctctggag atgcattgcc aaaaaaatat gcttgttggt tccagcagaa
      181 gccaggccag tcccctgtaa tgatcatcta tgaggacagc aaacggcccc ctgggatccc
      241 tgagagattc tctggctcca gctcagggac agtggccacc ttgactatca gtggggccca
      301 ggtggaggat gaagctgact actactgtta ctcaacagat agcagtacta atcatggctt
      361 attcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac
      421 tctcttcccg
//
LOCUS       KCVO01000765             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:19552:19764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000765
VERSION     KCVO01000765.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:19552:19764"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72794.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           99 a          144 c          120 g           97 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggtaccagca gaaaccaggc cagtccccta tgctgatcat
      241 ctatgaggac aacaaacggc cctctgggat ccctgaaaga ttctctggct ccagctcagg
      301 gacaatggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacaacagtg gtcagggctc attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000766             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:18679:13612
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000766
VERSION     KCVO01000766.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18679:13612"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..424
                     /note="immunoglobulin light chain variable region"
     V_region        101..424
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72795.1"
                     /translation="DYYCYSTDSSGHHRVF"
     J_segment       390..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>463
                     /gene="IGLC"
BASE COUNT           91 a          143 c          126 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tttgcttatt ggttccagca gaagccaggc cagtcccctg tggtgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctccgg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gatagtagtg gtcatcatag ggttttcggc ggagggaccc gactgaccgt
      421 cctacgtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000767             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:9759:16080
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000767
VERSION     KCVO01000767.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:9759:16080"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72796.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          144 c          125 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgacgac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcattggggc ccaggtggag gatgaagctg actaccactg
      361 tttctcaaca gatagcagtg gtaatcatag gggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000768             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:5955:15343
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000768
VERSION     KCVO01000768.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:5955:15343"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72797.1"
                     /translation="DYYCQSFDSSLSAVLF"
     J_segment       413..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           89 a          156 c          130 g          112 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cccgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcaccatctc
      181 ctgcactggg agcagctcca acattggagg ttattatgtg cagtggtacc agcaacttcc
      241 aggaacgtcc cccaaagttc tcgtctatga aaataataag cgaccctcag gggtttctga
      301 tcgattctct ggctcccagt ctggttcctc agcctccctg accatcactg gactgcagtc
      361 tgaggatgag gctgattatt actgccagtc ctttgacagc agcctgagtg ccgtgttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCVO01000769             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:24519:2877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000769
VERSION     KCVO01000769.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:24519:2877"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72798.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           85 a          155 c          123 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acactagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000770             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:12915:16342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000770
VERSION     KCVO01000770.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:12915:16342"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    59..383
                     /note="immunoglobulin light chain variable region"
     V_region        59..383
     V_segment       59..346
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <308..>355
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72799.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       350..383
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        384..>421
                     /gene="IGLC"
BASE COUNT           82 a          127 c          122 g           90 t
ORIGIN      
        1 acatgggggg acccttctcc tcctcggcct ccttgcttac tgcacaggct ctgcggtctc
       61 ctatgacctg actcagccac cctcggtgtc agtgtcccca ggacagacgg ccaggatcac
      121 ctgtgtggga gacaatgttg gaagtgaata tgtgcactgg taccaacaga agccaccgca
      181 ggcccctgtg gtggtcatcc attataatag tgaccggccc tcagggatcc ctgaacgatt
      241 ctctggctcc aaatcaggga gcgccgccac cctgaccatc agcggggtcg aggccgggga
      301 tgaggctgac tattactgtc aggtgtggga cagtagtagt gatcatagtt tattgggagg
      361 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      421 g
//
LOCUS       KCVO01000771             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:16844:5266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000771
VERSION     KCVO01000771.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16844:5266"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72800.1"
                     /translation="DYYCSSYADTYTFVF"
     J_segment       401..435
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           79 a          161 c          121 g          112 t
ORIGIN      
        1 acatgggggg gggtctcaga cggcagcgct ctcgggacat ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctcgctc agtgtctggg tctcctggac agtcggtcac catctcctgc actggcacca
      181 gcagtgacat cggtggttat aactttgtct cctggtacca acaccatcca ggcacagccc
      241 ccaaactcgt gatttatgag gtcactcagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcgacgcg gcctccctga ccatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgctcctca tatgcagaca cttacacttt tgtgttcgga agtggcacca
      421 agttgaccgt cctcggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01000772             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:13512:19606
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000772
VERSION     KCVO01000772.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13512:19606"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72801.1"
                     /translation="EYYCSSYADIYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          163 c          114 g          108 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg cctcaggcta ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca cgggcaccag
      181 cagtgacatc ggtggttaca actttgtctc ctggtaccaa caccatccag acacagcccc
      241 caaactcgtg atttatgagg tcactcaccg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctgga ctccaggctg acgacgaggc
      361 tgaatattac tgcagttcat atgcagacat ctacacattt gtgttcggaa gtggcaccaa
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01000773             448 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:10928:4001
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000773
VERSION     KCVO01000773.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 448)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 448)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:10928:4001"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..410
                     /note="immunoglobulin light chain variable region"
     V_region        120..410
     V_segment       120..376
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <338..>382
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72802.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       380..410
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>448
                     /gene="IGLC"
BASE COUNT           92 a          133 c          124 g           99 t
ORIGIN      
        1 acatggggat ataagagaag cctagggagc ccagctgtgc tgtgggctca ggaggcagag
       61 ctctgggtgt ctcaccatgg cctggattcc tctcctactc cccctcctca ctttctgcac
      121 agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc cagaaaaata
      181 tgctttttgg ttccagcaga agccaggcca gtcccctgtg ctgatcatca atgaggacaa
      241 caaacggccc tctgggatcc ctgggagatt ctctggctcc agctcaggga cagtggccac
      301 cttgactctc agtggggccc aggtggagga tgaagctgac tactactgtt cctcaacaga
      361 tagtagtggt aattatgtct tcggcggagg gacccggctg accgtcctag gtcagcccaa
      421 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000774             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:11930:2417
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000774
VERSION     KCVO01000774.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11930:2417"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72803.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          146 c          124 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgacgac agcaaacgcc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcattggggc ccaggtggag gatgaagctg actaccactg
      361 tttctcaaca gatagcagtg gtaatcatag gggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000775             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:15817:4962
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000775
VERSION     KCVO01000775.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:15817:4962"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72804.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          160 c          125 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc accaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000776             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:23131:10815
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000776
VERSION     KCVO01000776.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23131:10815"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..426
                     /note="immunoglobulin light chain variable region"
     V_region        99..426
     V_segment       99..387
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72805.1"
                     /translation="DYYCQSHDTGLKTLF"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           91 a          153 c          116 g          104 t
ORIGIN      
        1 acatgggggc acaggaggca gcactcagga cagtctccag catggcctcg tctcctctcc
       61 tcctcaccct tctcattcac tgcacagggt cctgggccca gtctgtgctg acacagccgc
      121 cctcagtgtc tggggcccca gggcagaggg tcaccatctc ctgcactggg ggcagctcca
      181 acattggagc ttattatgta tactggtacc agcagttccc aggaatggcc cccaaactcc
      241 tcatctatga caataataag cgactgtcag gggtttctga ccgattctct ggctccaagt
      301 ctggttcctc agcctccctg accatcactg ggctccagac tgaggatgag gctgattatt
      361 actgccagtc ccatgacact ggcctgaaaa ctttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000777             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:19445:10332
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000777
VERSION     KCVO01000777.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19445:10332"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72806.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           86 a          155 c          122 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgct catctctggg ctccagactg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagtacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000778             438 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:12424:5643
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000778
VERSION     KCVO01000778.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:12424:5643"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    76..397
                     /note="immunoglobulin light chain variable region"
     V_region        76..397
     V_segment       76..363
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <325..>372
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72807.1"
                     /translation="DYYCYSSDSSADYWVF"
     J_segment       364..397
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        398..>438
                     /gene="IGLC"
BASE COUNT           90 a          136 c          112 g          100 t
ORIGIN      
        1 acatgggggt gtctcaccat ggcctggatt cctctcctac tccccctcct cactttctgc
       61 acaggctctg cagcctccta tgaactgaca cagccaccct cggtgtcagt gtccccagga
      121 cagacggcca ggatcacctg ctctggagat gcattgccag aaaaatatgc ttattggttc
      181 caacagaagc caggccagtc ccctgtgttg atcatctatg aggacaacaa acggccctct
      241 gggatccctg agagattctc tggttccagc tcagggacag tggccacctt gactatcagt
      301 ggggcccagg tggaagatga agctgactac tactgttact catcagatag cagtgctgat
      361 tattgggtgt tcggcggagg gacccggctg accgtcccag gtcagcccaa ggctgccccc
      421 tcggtcactc tcttcccg
//
LOCUS       KCVO01000779             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:12853:12903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000779
VERSION     KCVO01000779.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12853:12903"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72808.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          143 c          125 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgacgac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcattggggc ccaggtggag gatgaagctg actaccactg
      361 tttctcaaca gatagtagtg gtaatcatag gggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000780             495 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:23708:12999
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000780
VERSION     KCVO01000780.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 495)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:23708:12999"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..455
                     /note="immunoglobulin light chain variable region"
     V_region        124..455
     V_segment       124..415
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <379..>429
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72809.1"
                     /translation="DYYCQSSDTSLNDHVLF"
     J_segment       420..455
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>495
                     /gene="IGLC"
BASE COUNT           97 a          160 c          124 g          114 t
ORIGIN      
        1 acatgggggg gggaagctct gcttcatctg tgggcacagg aggcagcact caggacagtc
       61 tccagcatgg cctcgtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg
      121 gcccagtctg tgctgacaca gccgccctca gtgtctgggg ccccagggca gagggtcacc
      181 atctcctgca ctgggagcag ttccaacatt ggaggttatt atgtatattg gtaccagcaa
      241 ctcccaggaa tggcccccaa actcctcatc tatgacaata ataagcgacc ctcaggggtt
      301 tctgaccgat tctctggctc caagtctggt tcctcagcct ccctgaccat cactgggctc
      361 cagactgagg atgaggctga ttattactgc caatcctctg acaccagcct aaatgatcat
      421 gtgttattcg gaggagggac ccggctgacc gtcctcggtc agcccaaggc tgccccctcg
      481 gtcactctct tcccg
//
LOCUS       KCVO01000781             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:10751:9796
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000781
VERSION     KCVO01000781.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:10751:9796"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72810.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       392..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           88 a          140 c          138 g           96 t
ORIGIN      
        1 atggggctgg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctta ctgcacagac tctgcggtct cctatgacct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaatgtt
      181 ggaagtgaat atgtgcactg gtaccaacag aaaccagcgc aggcccctgt ggtggtcatc
      241 cattataata gtgaccggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtagtag tgatcattgt gtattgggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000782             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:22361:7686
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000782
VERSION     KCVO01000782.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:22361:7686"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..400
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72811.1"
                     /translation="DYYCGSYEGSNTFLF"
     J_segment       401..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           88 a          156 c          122 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcggcactc tcgggacatc tccaccatgg cctgggatct
       61 gctcctcttc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctca atgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaatcag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcacg atttatgacg atggtcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaactcgg cctccctgac catctctggg ctccaagcag aggatgatgc
      361 tgattattac tgcggctcat atgaaggcag caacactttc ttattcggag gagggacccg
      421 gctgaccgtc ctgggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000783             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:14855:18896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000783
VERSION     KCVO01000783.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14855:18896"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72812.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          160 c          124 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atatactggt accagcagaa gccagggagc gttcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000784             382 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:25467:9707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000784
VERSION     KCVO01000784.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 382)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:25467:9707"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    14..344
                     /note="immunoglobulin light chain variable region"
     V_region        14..344
     V_segment       14..307
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <269..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72813.1"
                     /translation="DYYCQSYDTRLRAWVF"
     J_segment       308..344
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>382
                     /gene="IGLC"
BASE COUNT           76 a          120 c          102 g           84 t
ORIGIN      
        1 acatgggggg gcccagtctg tcctgacgca gccgccctca gtgtctgggg cgcccgggca
       61 gagggtcacc atctcctgca ctgggagcag ctccaacatt ggagattatt ttgtgcagtg
      121 gtaccaacag cttccaggaa cggcccccaa actcctcatc tatgaaaatg ataaacggcc
      181 ctcaggagtt tctgatcgat tctctggctc ccagtctgga acctcagcct ccctgaccat
      241 cactggactc cagtctgagg atgagactga ttattactgc cagtcctatg acaccagatt
      301 gagggcttgg gtattcggcg gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc
      361 cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000785             312 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:5886:6312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000785
VERSION     KCVO01000785.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 312)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 312)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5886:6312"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..272
                     /note="immunoglobulin light chain variable region"
     V_region        8..272
     V_segment       8..240
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <202..>246
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72814.1"
                     /translation="DYYCHSLDTSGNDVF"
     J_segment       244..272
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        273..>312
                     /gene="IGLC"
BASE COUNT           66 a           89 c           88 g           69 t
ORIGIN      
        1 acatggggga tcacctgctc tggagatgca ctgccaaaaa aatttgctta ctggttccag
       61 cagaagccag gccagtcccc tgtggcgatc atctatgagg acagcaaacg gccctctggg
      121 atccctgaga gattctctgg ctccagctca gggacagtgg ccaccttgac tatcagtggg
      181 gcccaggtgg aggatgaagc tgactactac tgtcattcat tagataccag tggtaatgat
      241 gttttcggcg gagggacccg gctgaccgtc ctgggtcagc ccaaggctgc cccctcggtc
      301 actctcttcc cg
//
LOCUS       KCVO01000786             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:6685:9825
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000786
VERSION     KCVO01000786.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:6685:9825"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..433
                     /note="immunoglobulin light chain variable region"
     V_region        107..433
     V_segment       107..402
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72815.1"
                     /translation="DYFCSSYTGSITLF"
     J_segment       403..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>472
                     /gene="IGLC"
BASE COUNT           86 a          159 c          118 g          109 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcaggac gtctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtgctt ataactatgt ctcctggtac caacggcacc caggcaaagc
      241 ccccaaactc atgatttatg atgtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaaa tctggcaaca cggcctccct gaccatctct gggctccagt ctgaggatga
      361 ggctgattat ttctgcagct catatacagg cagcatcact ttattcggag gagggacccg
      421 gctgaccgtc ctacgtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000787             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:16233:9632
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000787
VERSION     KCVO01000787.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:16233:9632"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..434
                     /note="immunoglobulin light chain variable region"
     V_region        106..434
     V_segment       106..400
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72816.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       401..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>474
                     /gene="IGLC"
BASE COUNT           87 a          157 c          121 g          109 t
ORIGIN      
        1 acatggggct gggatctcag gaggcagcac tctcaggacg tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagtctccct ctgtgtctgg gtctcctgga cagtcggtca ccatttcctg cactggaacc
      181 agcagtgaca ttggtgatta taaccgtgtc tcctggtacc aacaccaccc aggcaaagcc
      241 cccaaactca tgatttatga agtcagtgat cggccctcag gggtctctga tcgcttctct
      301 ggttccaagt ctggcaacac ggcctccctg atcatctctg ggctccaggc tgaggacgag
      361 gctgattatt actgcagctc atacacaagc agtagcactt gggtattcgg cggagggacc
      421 cggctgaccg tccttggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000788             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:26428:9677
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000788
VERSION     KCVO01000788.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:26428:9677"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..431
                     /note="immunoglobulin light chain variable region"
     V_region        108..431
     V_segment       108..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72817.1"
                     /translation="DYFCCSHADTYTFVF"
     J_segment       408..431
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>476
                     /gene="IGLC"
BASE COUNT           83 a          157 c          123 g          113 t
ORIGIN      
        1 acatgggggg ctggggtctc agacggcagc gctctcggga catctccacc atggcctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccctga
      121 ctcagcctcg ctcagtgtct gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga catcggtggt tataactttg tctcctggta ccaacaacat ccaggcacag
      241 tccccaaact catgatttat gaggtcaatc agcggccctc aggggtctct gatcgcttct
      301 ctggctcaaa gtctggcaac acggcctccc tgaccgtctc cggggtccag gctgaggacg
      361 aggctgatta tttctgctgc tcacatgcag acacctacac ttttgttttc ggaagtggca
      421 ccaggttgac cgtcgtcggt cagcccaagg cttccccctt ggtcactctg ttcccg
//
LOCUS       KCVO01000789             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:10322:9539
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000789
VERSION     KCVO01000789.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10322:9539"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72818.1"
                     /translation="DYYCTSYASTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           84 a          161 c          119 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttttgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcacctcat acgcaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000790             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:17090:10516
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000790
VERSION     KCVO01000790.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17090:10516"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72819.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          155 c          123 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000791             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:14120:8244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000791
VERSION     KCVO01000791.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14120:8244"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72820.1"
                     /translation="EYHCFSTDSSGNHRGSF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          144 c          126 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgacgac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcattggggc ccaggtggag gatgaagctg agtaccactg
      361 tttctcaaca gatagtagtg gtaatcatag gggctcattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000792             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:20329:14819
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000792
VERSION     KCVO01000792.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20329:14819"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72821.1"
                     /translation="DYYCSSYASSSTWIF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          156 c          122 g          106 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcata atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcag tagcacttgg atattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000793             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:10863:19099
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000793
VERSION     KCVO01000793.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10863:19099"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..431
                     /note="immunoglobulin light chain variable region"
     V_region        98..431
     V_segment       98..391
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72822.1"
                     /translation="DYYCSLWDSRLSSRVF"
     J_segment       396..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           92 a          149 c          122 g          106 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctctcct
       61 tctcactctg ctggttcact gcacagggtc ctgggcccag tctgtgctga cgcagccgcc
      121 ctcagcatct ggggcccccg ggcagagggt caccatctcc tgcactggga ccagctccaa
      181 cattggggcg aattattatg tttcctggta ccagcagttc ccaggaacag cccccaaact
      241 cctcatctat gaaaataata agcgaccctc aggggtttct gaccgattct ctggctccaa
      301 gtctggtacc tcagcctccc tgaccatctc tggactccaa tctgaggatg aggctgatta
      361 ttattgctca ctatgggata gcagactgag tagtcgggta ttcggcggag gtacccgact
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000794             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:20058:7157
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000794
VERSION     KCVO01000794.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:20058:7157"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..429
                     /note="immunoglobulin light chain variable region"
     V_region        107..429
     V_segment       107..388
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72823.1"
                     /translation="DYYCQVWDSSSDHWVF"
     J_segment       394..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>469
                     /gene="IGLC"
BASE COUNT           87 a          148 c          140 g           94 t
ORIGIN      
        1 acatgggggc agcctggcct cgggaagcag ccttggcggt gcctcagcca tggccgggac
       61 ccttctcctc ctcggcctcc ttgctcactg cacaggctct gcggtctcct atgaactaac
      121 tcagccacgc tcagtgtccg tgtccccagg acagacggcc cggatcacct gtgggggaga
      181 caacattgga agtaaaagtg tgcagtggtt ccagcagaag ccaccgcagg cccctgtact
      241 ggtcatttat ggtgatagcg aacggccctc agggatccct gagcgattct ctggctccaa
      301 ctcagggaac accgccaccc tgaccatcac cggggtcgag gccgggaatg aggctgacta
      361 ttattgtcag gtgtgggaca gtagtagtga tcattgggta ttcggcggag ggacccggct
      421 gaccgtcctc ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000795             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:9099:5311
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000795
VERSION     KCVO01000795.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:9099:5311"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72824.1"
                     /translation="DYYCYSTDTSGNHRVF"
     J_segment       390..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           97 a          144 c          123 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tactgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggcggag gatgaagctg actactactg
      361 ttactcaaca gataccagtg gtaatcatag ggtattcggc ggagggaccc gactgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000796             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:19537:13172
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000796
VERSION     KCVO01000796.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19537:13172"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..431
                     /note="immunoglobulin light chain variable region"
     V_region        98..431
     V_segment       98..391
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72825.1"
                     /translation="DYFCSVWDSSLSSYIF"
     J_segment       394..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           88 a          154 c          122 g          105 t
ORIGIN      
        1 acatgggggg gcacaggagg cagcactcag gacagtctcc agcatggcct ggtctctcct
       61 tctcactctg ctggttcact gcacagggtc ctgggcccag tctgtgctga cgcagccgcc
      121 ctcagcatct ggggcccccg ggcagagggt caccatctcc tgcactggga gcagctccaa
      181 catcggggcg gcttattctg tatcctggta ccagcagttc ccaggaacag cccccaaact
      241 cctcatctat gaaaataata agcgaccctc aggggtttct gaccgattct ctggctccaa
      301 gtctggtacc tcagcctccc tgaccatcac tggactccaa tctgaggatg aggctgatta
      361 tttctgctca gtctgggata gcagcctgag tagttacatc ttcggtgctg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000797             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:11676:13877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000797
VERSION     KCVO01000797.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11676:13877"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..396
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72826.1"
                     /translation="DYYCSSYTDSSTWVF"
     J_segment       397..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           88 a          155 c          120 g          107 t
ORIGIN      
        1 acatggggga tctcaggagg cagcactctc aggacgtctc caccatggcc tgggctctgc
       61 tcctcctcac cctcctcact cagggcacag gatcctgggc tcaggctgcc ctgactcagt
      121 ctccctctgt gtctgggtct cctggacagt cggtcaccat ttcctgcact ggaaccagca
      181 gtgacattgg tggttataac cgtgtctcct ggtaccaaca gcacccaggc aaagccccca
      241 aactcatgat ttatgaggtc aataatcggc cctcaggggt ctctgatcgc ttctctggct
      301 ccaagtctgg caacacggcc tccctgatca tctctgggtt ccaggctgag gacgaggctg
      361 attattactg cagctcatac acagacagta gcacttgggt attcggcgga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000798             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:23524:17506
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000798
VERSION     KCVO01000798.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23524:17506"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72827.1"
                     /translation="DYFCYSTTSSGNHRLF"
     J_segment       391..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           97 a          141 c          125 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tccaatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcact
      181 gccaaaaaaa tatgcttatt ggttccagca gaagacaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggaa gatgaagctg actacttctg
      361 ttactcaacg actagcagtg gtaatcatag gttattcgga ggagggaccc gggtgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000799             401 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:22671:13142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000799
VERSION     KCVO01000799.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 401)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:22671:13142"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    33..363
                     /note="immunoglobulin light chain variable region"
     V_region        33..363
     V_segment       33..327
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <291..>335
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72828.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       328..363
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        364..>401
                     /gene="IGLC"
BASE COUNT           75 a          125 c          107 g           94 t
ORIGIN      
        1 acatgggcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag tctccctctg
       61 tgtctgggtc tcctggacag tcggtcacca tttcctgcac tggaaccagc agtgacattg
      121 gtggttataa ccgtgtctcc tggtaccaac agcacccagg caaagccccc aaactcatga
      181 tttatgaggt cagtaatcgg ccctcagggg tctctgatcg cttctctggt tccaagtctg
      241 gcaacacggc ctccctgatc atctctgggc tccaggctga ggacgaggct gattattact
      301 gcagctcata tgcaagcagt agcacttggg ttttcggcgg agggacccgg ctgaccgtcc
      361 taggtcaggc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000800             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:25860:5003
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000800
VERSION     KCVO01000800.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:25860:5003"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..439
                     /note="immunoglobulin light chain variable region"
     V_region        106..439
     V_segment       106..399
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72829.1"
                     /translation="DYYCGSYGSGSTHGLF"
     J_segment       402..439
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           81 a          156 c          131 g          109 t
ORIGIN      
        1 acatgggggt gggatctcag gaggcagcgc tctcgggacg tctccaccat ggcttgggct
       61 ctggtcctcc tcaccctcct cactcagggc tcaggatcct gggctcagtc tgccctgact
      121 cagcctccct cagtgtccaa gtctcttgga cagtcggtca ccatctcctg cactggaacc
      181 cgcagtgaca ttggtggtta taacggtgtc tcctggtacc agcagcactc aggcacagcc
      241 cccagactcc tgatttatga ggtcactaag cggccctcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg agcatctctg ggctccaggc tgaggatgag
      361 gctgattatt actgcggctc atatggcagt ggaagcactc atggcttatt cggaggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000801             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:21698:11677
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000801
VERSION     KCVO01000801.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:21698:11677"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72830.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           90 a          140 c          117 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatttg
      181 cttattggtt ccaacagaag ccaggccagt cccctgtgct gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aaggtgacta ctactgttcc tcaacagata
      361 gcagtggtaa ttatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000802             370 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:6678:8028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000802
VERSION     KCVO01000802.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 370)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 370)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:6678:8028"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..332
                     /note="immunoglobulin light chain variable region"
     V_region        8..332
     V_segment       8..297
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <260..>304
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72831.1"
                     /translation="DYYCSSYAGSDTLIF"
     J_segment       299..332
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        333..>370
                     /gene="IGLC"
BASE COUNT           72 a          121 c           91 g           86 t
ORIGIN      
        1 acatggggcc ctgactcagc ctccctcaat gtctgggtct cctggacagt cggtcaccat
       61 ctcctgcact ggaaccagca gtgacattgg tagttataac cgtgtctcct ggtaccaaca
      121 gcacccaggc aaagccccca aactcatgat ttatgacgtc agtcagcggc cctcaggggt
      181 ctctgatcgc ttctctggct ccaagtctgg caacacggcc tccctgacca tctctgggct
      241 ccaggctgag gatgaggctg attattactg cagctcatat gcaggcagcg acactttaat
      301 cttcggtggt gggacccggc tcactgtcct aggtcagccc aaggcttccc ccacggtcac
      361 tctgttcccg
//
LOCUS       KCVO01000803             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:13448:16235
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000803
VERSION     KCVO01000803.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13448:16235"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72832.1"
                     /translation="DYYCYSTISSGNDRIF"
     J_segment       392..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           95 a          139 c          123 g          106 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gtcaaaaaaa tatgtttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca attagtagtg gtaatgatag gatcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000804             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:20889:14865
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000804
VERSION     KCVO01000804.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20889:14865"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72833.1"
                     /translation="EYYCSSYADIYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          164 c          115 g          109 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tggcctcagg ctaccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcacgggcac
      181 cagcagtgac atcggtggtt acaactttgt ctcctggtac caacaccatc cagacacagc
      241 ccccaaactc gtgatttatg aggtcactca ccggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct ggactccagg ctgacgacga
      361 ggctgaatat tactgcagtt catatgcaga catctacaca tttgtgttcg gaagtggcac
      421 caagttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01000805             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:14493:5936
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000805
VERSION     KCVO01000805.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14493:5936"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72834.1"
                     /translation="DYYCSSYISSSTWVF"
     J_segment       402..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           88 a          154 c          121 g          112 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tggcctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtaa tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaagacga
      361 ggctgattat tactgcagct catatataag tagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000806             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:21189:15542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000806
VERSION     KCVO01000806.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:21189:15542"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..215
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72835.1"
                     /translation="DYYCSSYADTTTWLF"
     J_segment       216..251
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           56 a           95 c           73 g           65 t
ORIGIN      
        1 acatgggggt ggttataacc gtgtctcctg gtaccaacag cacccaggca aagcccccaa
       61 actcatgatt tatgacgtca gtgatcggcc ctcaggggtc tctgatcgct tctctggttc
      121 caagtctggc aacacggcct ccctgatcat ctctgggctc caggctgagg acgaggctga
      181 ttattactgc agctcatacg cagacactac cacttggcta ttcggcggag ggacccgcct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000807             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:13580:17684
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000807
VERSION     KCVO01000807.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:13580:17684"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..387
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72836.1"
                     /translation="DYYCQVWDSSSAVLF"
     J_segment       390..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          140 c          139 g           99 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgctcactgc acagactctg tggtctccta tgagttgact
      121 cagccacgct cagtgtccgt gtccccagga cagacggcca ggatcacctg tgggggatac
      181 atcattggaa gtaaaagtgt gcagtggtac cagcagaagt caccgcaggc ccttgtgctg
      241 gtcatctatg ctgataacaa acggccctca gggatccctg agcgattctc tggctccaat
      301 ttagggatca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggcagactat
      361 tactgtcagg tgtgggacag tagtagtgct gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000808             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:11836:3802
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000808
VERSION     KCVO01000808.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11836:3802"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..440
                     /note="immunoglobulin light chain variable region"
     V_region        119..440
     V_segment       119..404
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72837.1"
                     /translation="DYYCQVWDSSRKFLF"
     J_segment       407..440
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           96 a          149 c          140 g           93 t
ORIGIN      
        1 acatggggga ggcacctgcc ctgtctgggc ctcaggaggc agcattgacg gtgcctcagc
       61 catggcctgg acccttctcc tcctcggcct cctcgctcac tgcacagact ctgcggcctc
      121 ctatgatctg actcagccac cctcggtgtc agcggcctca ggacagacgg ccaagatcac
      181 ctgtggggga gacagcattg gaagtgaaaa tgtacactgg taccagcaga agccagcgca
      241 ggcccctgtg gtggtcatct atgctgatag caaacggccc tcagggatcc ctgaacgatt
      301 ctctggctcc agctcaggga acaccgccac cctgaccatc agcagggtcg aggccgggga
      361 tgaggctgac tattactgtc aggtgtggga cagtagtaga aaatttttat tcggaggagg
      421 gacccgggtg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000809             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:16483:12412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000809
VERSION     KCVO01000809.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16483:12412"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..426
                     /note="immunoglobulin light chain variable region"
     V_region        103..426
     V_segment       103..398
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72838.1"
                     /translation="DYFCCSYADTYTFVF"
     J_segment       403..426
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>471
                     /gene="IGLC"
BASE COUNT           83 a          156 c          120 g          112 t
ORIGIN      
        1 acatgggggg gtctcagacg gcagcgctct cgggacatct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 cctcgctcag tgtctgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgacatcg gtggttataa ctttgtctcc tggtaccaac aacatccagg cacagccccc
      241 aaactcatga tttatgaggt caatcagcgg ccctcagggg tctctgatcg cttctctggc
      301 tcaaagtctg gcaacacggc ctccctgacc gtctccgggg tccaggctga ggacgaggct
      361 gattatttct gctgctcata tgcagacacc tacacttttg ttttcggaag tggcaccagg
      421 ttgaccgtcg tcggtcagcc caaggcttcc cccttggtca ctctgttccc g
//
LOCUS       KCVO01000810             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:19281:14462
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000810
VERSION     KCVO01000810.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:19281:14462"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72839.1"
                     /translation="DYYCQVWDSSSDVFF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          143 c          139 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcattggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttctactgg
      241 tcatctatgc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttcttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000811             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:13824:19238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000811
VERSION     KCVO01000811.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13824:19238"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72840.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       388..421
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           94 a          142 c          124 g           99 t
ORIGIN      
        1 acatgggggg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactccccc tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agatgcattg
      181 ccagaaaaat atgcttattg gttccagcag aagccaggcc agtcccctgt gttgatcatc
      241 aatgaggaca gcaaacggcc ctctgggatc cctgagagaa tctctggctc cagctcaggg
      301 acagtggcca ccttgactct cagtggggcc caggtagagg atgaagctga ctactactgt
      361 tcctcaacag atagtagtgg taatcatgta ttcggcggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000812             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:11910:14470
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000812
VERSION     KCVO01000812.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:11910:14470"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72841.1"
                     /translation="DYYCQVWDSSSKYAIF"
     J_segment       393..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          148 c          136 g           88 t
ORIGIN      
        1 acatgggggg gtctcaggag gcagcattga cggtgcctca gccatggcct ggacccttct
       61 cctcctcggc ctcctcgctc actgcacagg ctctgcgacc tcctatgagg tgactcagcc
      121 accctcggtg tcagcggcct caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaga aatgtccact ggtaccagca gaagccaccg caggcccctg ttctggtcat
      241 ctatgctgat gccaaacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtaaatacgc gatattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000813             310 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:17572:6501
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000813
VERSION     KCVO01000813.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 310)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 310)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17572:6501"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..271
                     /note="immunoglobulin light chain variable region"
     V_region        8..271
     V_segment       8..230
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <194..>244
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72842.1"
                     /translation="NYYCLSYDTSLSGHGLF"
     J_segment       235..271
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        272..>310
                     /gene="IGLC"
BASE COUNT           64 a           97 c           78 g           71 t
ORIGIN      
        1 acatgggggg agcagctcca acattggagg ttattctgta tcctggtgcc agaagttccc
       61 agaaacgacc cccaacctcc tcgactatca agataatagg cgaccctcag gggtttctga
      121 ccggttctct ggctccaagt ctggtccctc agcctccctg accatcactg ggctccagac
      181 tgaggatggg actaattatt actgcctgtc gtatgacacc agcctgagtg gtcatggctt
      241 attcggagga ggaacccggc tgaccgtcct aagtcagccc aaggctgccc cctcggtcac
      301 tctcttcccg
//
LOCUS       KCVO01000814             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:21638:8145
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000814
VERSION     KCVO01000814.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21638:8145"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72843.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           85 a          160 c          121 g          107 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgac gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacgcaagca ctaccacttg gctattcggc ggagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000815             348 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:21095:10695
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000815
VERSION     KCVO01000815.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 348)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 348)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..348
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:21095:10695"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..310
                     /note="immunoglobulin light chain variable region"
     V_region        91..310
     V_segment       91..270
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <232..>282
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72844.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       274..310
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        311..>348
                     /gene="IGLC"
BASE COUNT           66 a          108 c           97 g           77 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccctcctc actttctgca cagaagccag gccagtcccc tgtgctgatc
      121 atctatgacg acagcaaacg gccctctggg atccctgaga gattctctgg ctccagctca
      181 gggacagtgg ccaccttgac tatcattggg gcccaggtgg aggatgaagc tgactaccac
      241 tgtttctcaa cagatagcag tggtaatcat aggggcttat tcggaggagg gacccggctg
      301 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000816             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:16739:8535
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000816
VERSION     KCVO01000816.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:16739:8535"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..430
                     /note="immunoglobulin light chain variable region"
     V_region        104..430
     V_segment       104..399
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72845.1"
                     /translation="DYFCSSYTGSITLF"
     J_segment       400..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>469
                     /gene="IGLC"
BASE COUNT           86 a          157 c          117 g          109 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcaggacgtc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtgcttata actatgtctc ctggtaccaa cggcacccag gcaaagcccc
      241 caaactcatg atttatgatg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaaatct ggcaacatgg cctccctgac catctctggg ctccagtctg aggatgaggc
      361 tgattatttc tgcagctcat atacaggcag catcacttta ttcggaggag ggacccggct
      421 gaccgtccta cgtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000817             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:13789:10020
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000817
VERSION     KCVO01000817.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:13789:10020"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72846.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       413..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          155 c          131 g          110 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgttga cgcagccgcc ctcagtgtct ggggaccccg ggcagagggt caccatctcg
      181 tgcactggga gcagctccaa cattggaggt tattttgtat actggtacca gcagttccca
      241 ggaacagccc ccaaattcct catctatgac aatagtaagc gaccctcagg gatttctgac
      301 cgattctctg gctccaagtc tggtacctca gcctccctga ccatcactgg gctccagcct
      361 ggggatgagg ctgattatta ctgcggagca tgggatagca gcctgagtgc tcgcttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01000818             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:8793:6741
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000818
VERSION     KCVO01000818.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8793:6741"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72847.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           87 a          156 c          121 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa caccacccag gcaaagcccc
      241 caaactcatg atttatgaag tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000819             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:8867:12804
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000819
VERSION     KCVO01000819.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8867:12804"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72848.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       396..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          145 c          133 g           98 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgag ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaacc
      181 ttggagataa atatctacat tggtaccacc agaagccagc gcaggcccct gtgctggtca
      241 tctactatga tagtgaccgg ccctcatgga tccctgagcg attctctggg tccaagtcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtaat aatgatcata tctttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000820             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:13331:18300
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000820
VERSION     KCVO01000820.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13331:18300"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72849.1"
                     /translation="DYYCSSYADTSTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          157 c          123 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcagacac tagcacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000821             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:24310:10099
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000821
VERSION     KCVO01000821.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:24310:10099"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72850.1"
                     /translation="DYYCQVWDITTDHDVF"
     J_segment       389..425
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>464
                     /gene="IGLC"
BASE COUNT           95 a          137 c          130 g          102 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatgacct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ttctgcggcc tcctatgagc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaaa aatgtgcact ggtaccagca gaagccaccg caggcccctg tattggtcat
      241 ctattatgat agcaaacggc cctcagggat ccctgagcga ttctctggcg ccaaatcagg
      301 gaacaccgcc accctgatca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattacta ctgatcatga tgtgttcgga agtggcacca agttgaccgt
      421 cctcggtcag cccaaggctt cccccttggt cactctgttt cccg
//
LOCUS       KCVO01000822             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:24379:9871
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000822
VERSION     KCVO01000822.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:24379:9871"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72851.1"
                     /translation="DYYCQSYDTRLRAWVF"
     J_segment       414..450
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           95 a          159 c          127 g          107 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct
      181 cctgcactgg gagcagctcc aacattggag actattttgt gcagtggtac caacagcttc
      241 caggaacggc ccccaaactc ctcatctatg aaaatgataa acgaccctca ggaacttctg
      301 atcgattctc tggctcccag tctggaacct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacac cagattgagg gcttgggtat
      421 tcggcggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCVO01000823             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1101:22924:8542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000823
VERSION     KCVO01000823.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:22924:8542"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72852.1"
                     /translation="DYYCYSTRSSGYHGLF"
     J_segment       375..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           91 a          139 c          116 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatctct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag atgcaggatg aaggtgacta ctactgttac tcaactcgta
      361 gtagcggtta tcatggctta ttcggaggag ggacctggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000824             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:18881:6729
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000824
VERSION     KCVO01000824.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18881:6729"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..412
                     /note="immunoglobulin light chain variable region"
     V_region        87..412
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72853.1"
                     /translation="DYYCFSTDTSGNHRGFF"
     J_segment       378..412
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>452
                     /gene="IGLC"
BASE COUNT           89 a          142 c          119 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcg
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgtattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaagacagca
      241 accggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgtttc tcaacagata
      361 ccagtggtaa tcataggggc ttcttcggag gagggacccg gctgaccgtc ctgggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000825             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:12041:22338
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000825
VERSION     KCVO01000825.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12041:22338"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..409
                     /note="immunoglobulin light chain variable region"
     V_region        88..409
     V_segment       88..375
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72854.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       376..409
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           92 a          139 c          115 g          101 t
ORIGIN      
        1 tcaggaggcc acagctctgg gtgtctcacc atggcctgga ttcctctcct actccccctc
       61 ctcactttct gcacaggctc tgcagcctcc tatgagctga cacagcaacc ttcggtgtca
      121 gtgtctccag gacagacggc caggatcacc tgctctggag atgcattgcc agaaaaatat
      181 gcttattggt tccagcagaa gccagaccag tcccctgtgt tgatcatcaa tgaggacagc
      241 aaacggccct ctgggatccc tgagagattc tctggctcca gctcagggac agtggccacc
      301 ttgactctca gtggggccca ggtggaggat gaagctgact actattgttc ctcaacagat
      361 agcagtggta atcatgtatt cggcggaggg acccggctga ccgtcctagg tcagcccaag
      421 gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000826             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:9480:13027
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000826
VERSION     KCVO01000826.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:9480:13027"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72855.1"
                     /translation="DYYCQVWDSNSDHPIF"
     J_segment       395..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           81 a          149 c          135 g          102 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagtctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac ggacggcccg gatcacctgt gggggagaca
      181 tcgttggaag tgaatatgtt cactggtatc agcagaagtc agcgcaggcc cctgtggtgg
      241 tcatctatta ttattctgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggagcac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactact
      361 actgtcaggt gtgggacagt aatagtgatc atcccatctt cggtcctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01000827             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:17610:4659
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000827
VERSION     KCVO01000827.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17610:4659"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72856.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          144 c          125 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ttctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgacgac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcattggggc ccaggtggag gatgaagctg actaccactg
      361 tttctcaaca gatagcagtg gtaatcatag gggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000828             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:12954:6877
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000828
VERSION     KCVO01000828.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12954:6877"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72857.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       391..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          142 c          127 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgtttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcagacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccagggggag gatgaagctg actactactg
      361 ttattcaatg gatagcagtg gtactcagag catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01000829             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:12803:3532
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000829
VERSION     KCVO01000829.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:12803:3532"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72858.1"
                     /translation="DYYCYSTDSSGNQHIF"
     J_segment       376..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           93 a          139 c          116 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcgt atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaggacagga
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttat tcaacagata
      361 gcagtggtaa tcagcacatc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000830             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:14650:8784
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000830
VERSION     KCVO01000830.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14650:8784"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72859.1"
                     /translation="DYFCSSYTADNTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           84 a          157 c          118 g          113 t
ORIGIN      
        1 acatgggggg ggtctcagaa ggcagcgctc tcaggacgtc tccaccatgg cctggactct
       61 gctcctcgtc accctcctca ctcaaggcac aggatcctgg gctcagtctg ccccgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatatt gggtattata atgttgtgtc ttggtaccaa cagcacccag acacagcccc
      241 caaactcatg atttatggtg tcactaatcg gccctcaggg gtctctgatc gcttctctgg
      301 ctcccagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 cgattatttc tgttcttcat atacagccga taacacttgg gttttcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000831             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:27342:19783
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000831
VERSION     KCVO01000831.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:27342:19783"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72860.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          161 c          123 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atatactggt accagcagaa gccagggagc actcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000832             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:17613:9015
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000832
VERSION     KCVO01000832.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17613:9015"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72861.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           86 a          160 c          120 g          107 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgac gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca ctaccacttg gctattcggc ggagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000833             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:7808:10947
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000833
VERSION     KCVO01000833.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:7808:10947"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..425
                     /note="immunoglobulin light chain variable region"
     V_region        103..425
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72862.1"
                     /translation="DYYCQVWDFSGDHNIF"
     J_segment       392..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>465
                     /gene="IGLC"
BASE COUNT           89 a          148 c          129 g           99 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatgac ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctctga gttgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagaa tcacctgtgg gagagacaac
      181 attggaaata agaatgtgca ctggtaccag cagcggccac cgcgggcccc tgtactggtc
      241 atctattatg ataccgaacg gccctcaggg atccctgagc gattctctgg ctccacatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggactttag tggtgatcat aacatcttcg atgctgggac ccggctcacc
      421 gtcctcggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCVO01000834             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:8585:10392
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000834
VERSION     KCVO01000834.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8585:10392"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..433
                     /note="immunoglobulin light chain variable region"
     V_region        107..433
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72863.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       402..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>475
                     /gene="IGLC"
BASE COUNT           86 a          156 c          123 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggttatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catatgcaag cactagcact tggctattcg gcggagggac
      421 ccggctgacc gtcgtaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000835             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:10011:4089
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000835
VERSION     KCVO01000835.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10011:4089"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..392
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72864.1"
                     /translation="DYYCAAWDDSLSSPFF"
     J_segment       399..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          153 c          117 g          108 t
ORIGIN      
        1 acatgggggt acagaaggca ggactcagga taatctccag catggcctgg ttccctctcg
       61 tcctcaccct cctcactcac tgtgcagggt cctgggccca gtctgtggtg actcagccac
      121 cctcaacgtc tggggctccc gggcagagtg tcaccatctc ttgttctgga agcagctcca
      181 acattggaag taattatgta aactggtacc agcaactccc aggaacggcc cccaaactcc
      241 tcatctattt tactaatcag cgaccctcag gggtccctga ccgattctct ggctctaagt
      301 ctggcacctc agcctccctg gccatctctg gtctccgatc tgaggatgag gctgattatt
      361 actgtgcggc atgggatgac agcctgagca gtcccttctt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000836             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:1926:12778
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000836
VERSION     KCVO01000836.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:1926:12778"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..444
                     /note="immunoglobulin light chain variable region"
     V_region        117..444
     V_segment       117..405
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <372..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72865.1"
                     /translation="DYYCQSHDTGLKTLF"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          158 c          121 g          111 t
ORIGIN      
        1 acatgggggc tctgcttcat ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctcgtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac acagccgccc tcagtgtctg gggccccagg gcagagggtc accatctcct
      181 gcactggggg cagctccaac attggagctt attatgtata ctggtaccag cagttcccag
      241 gaatggcccc caaactcctc atctatgaca ataataagcg actgtcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggttcctcag cctccctgac catcactggg ctccagactg
      361 aggatgaggc tgattattac tgccagtccc atgacactgg cctgaaaact ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000837             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:15067:12308
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000837
VERSION     KCVO01000837.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15067:12308"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72866.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       396..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          145 c          133 g           98 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gttctgcggt ctcctatgag ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaacc
      181 ttggagataa atatctacac tggtaccacc agaagccagc gcaggcccct gtgctggtca
      241 tctactatga tagtgaccgg ccctcatgga tccctgagcg attctctggg tccaagtcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtaat aatgatcata tctttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000838             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:22459:17895
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000838
VERSION     KCVO01000838.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:22459:17895"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72867.1"
                     /translation="DYYCGSYRSGNIYIF"
     J_segment       399..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           84 a          154 c          125 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcgggacgtc tccaccatgg cttgggctct
       61 ggtcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtccgtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttata acggtgtctc ctggtaccag cagcactcag gcacagcccc
      241 cagactcctg atttatgagg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcggctcat ataggagtgg aaacatttac atcttcggtg gtgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01000839             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:13953:7097
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000839
VERSION     KCVO01000839.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:13953:7097"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72868.1"
                     /translation="DYYCMIWHNNAWVF"
     J_segment       403..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           95 a          154 c          115 g          112 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgagcagt ggcatcagtg
      181 ttgatactta caggatattc tggtaccagc agatgccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gataaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttgggtattc ggcggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000840             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:16148:17505
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000840
VERSION     KCVO01000840.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16148:17505"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..395
                     /gene="IGLV10-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72869.1"
                     /translation="DYYCSAWDSSLSVVLF"
     J_segment       401..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT          105 a          157 c          125 g           85 t
ORIGIN      
        1 acatggggaa agcagagctt cggcaagcac agtgggaatc cgcaccatgc cctgggctct
       61 gctcctcctg accctcctca ctcactctgc agtgccagtg gtccaggcag ggctgactca
      121 gccaccctca gtgtccaagg gcttgagaca gacggccacg ctcacctgca ctggaaacag
      181 caacaatgtt ggcaaccagg gagcaggttg gctgcagcag caccagggcc accctcccaa
      241 actgctgtcc tacaggaata acaaccggcc ctcggggatc tcagagagat tctctgcatc
      301 caggtcagga aacacagcct ccctgaccat caccggactc caacctgagg atgaggctga
      361 ctattactgc tcagcatggg acagcagcct cagtgttgtt ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000841             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:16543:13322
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000841
VERSION     KCVO01000841.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:16543:13322"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..402
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72870.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       403..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           86 a          161 c          121 g          108 t
ORIGIN      
        1 acatgggggg ctgggatctc aggaggcagc actctcagga cgtctccacc atggcctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccctga
      121 ctcagtctcc ctctgtgtct gggtctcctg gacagtcggt caccatttcc tgcactggaa
      181 ccagcagtga cattggtggt tataaccgtg tctcctggta ccaacagcac ccaggcaaag
      241 cccccaaact catgatttat gacgtcagtg atcggccctc aggggtctct gatcgcttct
      301 ctggttccaa gtctggcaac acggcctccc tgatcatctc tgggctccag gctgaggacg
      361 aggctgatta ttactgcagc tcatacacaa gcactaccac ttggctattc ggcggaggga
      421 cccgcctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000842             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:13990:3960
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000842
VERSION     KCVO01000842.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:13990:3960"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72871.1"
                     /translation="EYHCFSTDSSGNHRGLF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           92 a          141 c          117 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag ccaggccagt cccctgtact gatcatctat gacgacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcat tggggcccag gtggaggatg aagctgagta ccactgtttc tcaacagata
      361 gtagtggtaa tcataggggc ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000843             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:12636:19639
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000843
VERSION     KCVO01000843.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12636:19639"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72872.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           83 a          152 c          125 g          113 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggtttt gagcgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactctt gatttatgag gtcagttatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tgccaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ttgcagctca tacacaagta gtagtacttg ggtattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000844             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:12049:7082
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000844
VERSION     KCVO01000844.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12049:7082"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72873.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           91 a          142 c          117 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gacgacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcat tggggcccag gtggaggatg aagctgacta ccactgtttc tcaacagata
      361 gcagtggtaa tcataggggc ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000845             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:19664:11974
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000845
VERSION     KCVO01000845.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19664:11974"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..306
                     /note="immunoglobulin light chain variable region"
     V_region        87..306
     V_segment       87..266
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <228..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72874.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       270..306
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           66 a          107 c           95 g           76 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacaga agccaggcca gtcccctgtg ctgatcatct
      121 atgacgacag caaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      181 cagtggccac cttgacgatc attggggccc aggtcgagga tgaagctgac taccactgtt
      241 tctcaacaga tagtagtggt aatcataggg gcttattcgg aggagggacc cggctgaccg
      301 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000846             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:12435:4773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000846
VERSION     KCVO01000846.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12435:4773"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..453
                     /note="immunoglobulin light chain variable region"
     V_region        120..453
     V_segment       120..413
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72875.1"
                     /translation="DYYCLSYDSSLSAHYIF"
     J_segment       416..453
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           97 a          164 c          121 g          109 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctc gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacacagcca ccctcagtgt ctggggcccc agggcagagg gtcaccatct
      181 cgtgcactgg gagcagctcc agaattggag gtgattatgt atcctggtac caacagctcc
      241 caggaaaggc ccccaaactc ctcatctatc aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtacct cagcctccct gaccatcact gggctccaga
      361 ctgaggatga ggctgattac tactgcctgt cctatgacag cagcctgagt gctcattaca
      421 tcttcggtcc tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca
      481 ctctgttccc g
//
LOCUS       KCVO01000847             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:20824:15330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000847
VERSION     KCVO01000847.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20824:15330"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72876.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       394..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           93 a          143 c          126 g          106 t
ORIGIN      
        1 acatgggggt gtgggctcag gaggcagagc tctgggtgtc tcaccatggc ctggattcct
       61 ctcctactcc ccctcctcac tttctgcaca ggctctgcag cctcctatga gctgacacag
      121 cctccctcgg tgtcagtgtc cccaggacag acggccagga tctcctgctc tggagatgca
      181 ttgccaaaaa aatttgcttc ttggttccag cagaaggcag gccagtcccc tgtgctgatc
      241 atctatgagg acagcaaacg gccctctggg atccctgaga gattctctgg ctccagttca
      301 gggacaatgg ccaccttgac tatcagtggg gcccaggtgg aggatgaagc tgactactac
      361 tgttactcaa cagataacag tgatactcat aggggcttct tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000848             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:20488:17894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000848
VERSION     KCVO01000848.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20488:17894"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72877.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       398..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          142 c          140 g           97 t
ORIGIN      
        1 acatgggggt gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acagactctg cggtctccta tgacctgact
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 aatgttggaa gtgaatatgt gcactggtac caacagaaac cagcgcaggc ccctgtggtg
      241 gtcatccatt ataatagtga ccggccctca gggatccctg agcgattctc tggctccaaa
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag tagtagtgat cattgtgtat tgggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000849             300 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:18423:11137
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000849
VERSION     KCVO01000849.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 300)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18423:11137"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..262
                     /note="immunoglobulin light chain variable region"
     V_region        5..262
     V_segment       5..225
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <187..>234
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72878.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       229..262
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        263..>300
                     /gene="IGLC"
BASE COUNT           65 a           82 c           91 g           62 t
ORIGIN      
        1 acatggggag acaatgttgg aagtgaatat gtgcactggt accaacagaa gccaccgcag
       61 gcccctgtgg tggtcatcca ttataatagt gaccggccct cagggatccc tgaacgattc
      121 tctggctcca aatcagggag cgccgccacc ctgaccatca gcggggtcga ggccggggat
      181 gaggctgact attactgtca ggtgtgggac agtagtagtg atcatagttt attgggagga
      241 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000850             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:11875:16935
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000850
VERSION     KCVO01000850.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:11875:16935"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72879.1"
                     /translation="DYYCYSSESSADYWVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           92 a          142 c          125 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgacgac accaaacggc cctctgggat ccctgagaga ttctctggtt ccagctcagg
      301 gacagtggcc accttgacta tcagtgggac ccaggtggag gatgaagctg actactactg
      361 ttactcatca gaaagtagtg ctgattattg ggtgttcggc ggagggaccc ggctgaccgt
      421 cccaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000851             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:15179:19683
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000851
VERSION     KCVO01000851.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15179:19683"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72880.1"
                     /translation="DYYCYSTDSSGNHIF"
     J_segment       374..408
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           92 a          143 c          111 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaagtatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gacgacagta
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagata
      361 gcagtggtaa tcacatcttc gctactggga cccggctcac cgtcctaggt cagcccaagg
      421 cttcccccac ggtcactctg ttcccg
//
LOCUS       KCVO01000852             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:17048:7265
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000852
VERSION     KCVO01000852.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17048:7265"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72881.1"
                     /translation="DYYCQVWDSGHDHVFF"
     J_segment       394..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           86 a          144 c          137 g           95 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggtct cctatgagct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacctt
      181 ggagataaat atgtacactg gtaccagcag aagccagcgc aggcccctgt gctggtcatc
      241 tactatgata gtgaccggcc ctcacggatc actgagcgat tctctgggtc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtggtca tgatcatgtc tttttcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000853             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:19441:11784
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000853
VERSION     KCVO01000853.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19441:11784"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72882.1"
                     /translation="EYYCSSYADIYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          160 c          118 g          109 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg cctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca cgggcaccag
      181 cagttacatc ggtggttaca actttgtctc ctggtaccaa caccatccag acacagcccc
      241 caaactcgtg atttatgagg tcactcagcg gccctcaggg gtctctgatc ggttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgaatattac tgcagttcat atgcagacat ctacacattt gtgttcggaa gtggcaccaa
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01000854             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:9042:9397
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000854
VERSION     KCVO01000854.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9042:9397"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72883.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       395..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           93 a          156 c          117 g          103 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cctcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccaggaagag tgtcaccatc tcctgttctg gaagcacctc
      181 caacatcgga actaatagtg tatcctggta ccagcagctc ccagaaacgg ctcccaaact
      241 cctcatctat tataatgatc gacgagcctc aggtgtctct gaccgattct ctggctccaa
      301 gtctggcacg tcagcctccc tggccatcag tgggctccag accgaggatg aggctgatta
      361 ttactgcgca gcatgggata acagcctgag cggttacatc ttcggtgctg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000855             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:16547:9571
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000855
VERSION     KCVO01000855.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:16547:9571"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72884.1"
                     /translation="DYYCQVWDSSSDHILF"
     J_segment       394..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          145 c          137 g           98 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gtctcctatg agttgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 ccttggagat aaatatgtac actggtacca gcagaagcca ccgcgggccc ctgtgctggt
      241 catctactat gatagtgacc ggccctcatg gatccctgag cgattctctg ggtccaaatc
      301 agggatcacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta gtagtgatca tatcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000856             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:12105:9942
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000856
VERSION     KCVO01000856.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12105:9942"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72885.1"
                     /translation="DYYCCSYTISTTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          151 c          120 g          114 t
ORIGIN      
        1 acatgggggg ggtctcagaa ggcagcgctc tcaggacgtc tccaccatgg cctggactct
       61 gctcctcgtc accctcctca ctcaaggcac aggatcctgg gctcagtctg ccccgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccaa
      181 cagtgatatt gggtattata atgctgtgtc ttggtaccaa cagcacccag gcacagcccc
      241 caaagtcatg atttatggtg tcagtaatcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattat tgttgttcat atacaatcag taccacttgg gtattcggcg gagggacccg
      421 gctgaccgtt ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000857             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:21513:16989
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000857
VERSION     KCVO01000857.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:21513:16989"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72886.1"
                     /translation="DYYCQVWDSNSDHWVF"
     J_segment       392..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          147 c          137 g           95 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca caggctctgc ggtctcctat gagttgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggcccg gatcacctgt gggggagaca
      181 acattggaag taaaagtgta cagtggttcc accagaagcc accgcaggcc cctgtgctgg
      241 tcatttatgc tgatagcgaa cggccctcag ggatccctga acgattctct ggctccaact
      301 cagggaatac cgccaccctg accatcagcg gggtcgaggc cggcaatgag gctgactatt
      361 actgtcaggt gtgggacagt aatagtgatc attgggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000858             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:29315:10022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000858
VERSION     KCVO01000858.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:29315:10022"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72887.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       390..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           90 a          144 c          125 g           99 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 cagaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgtg ctgatcatca
      241 atgaggacag caaacggccc tctgggatcc ctgggagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactctc agtggggccc aggtggagga tgaagctgac tactactgtt
      361 cctcaacaga cagtagtggt aattatgtct tcggcggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000859             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:23626:18101
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000859
VERSION     KCVO01000859.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23626:18101"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..391
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72888.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       397..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           99 a          137 c          126 g          105 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccctcctc actttctgca caggctctgc agcctcctat gagctgacac
      121 agtcaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg
      181 cattgccaaa aaaatatgta tattggttcc agcagaagcc aggccagtcc cctgtgttga
      241 tcatctatga ggacaacaaa cggccctctg ggattcctga gagattctct ggctccagct
      301 cagggacagt ggccaccttg actatcagtg gggcccaggt ggaggatgaa ggtgactact
      361 actgttactc aagagatagt agtgaaaatc aaagcgtctt cggtgctggg acccggctca
      421 gcgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01000860             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:23600:14040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000860
VERSION     KCVO01000860.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:23600:14040"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72889.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          156 c          127 g          111 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcaatgtctg gggcgcccgg gcagggggtc accatctcct
      181 gcactgggag cagctccaac attggagatt attatgtgca gtggtaccag cagtttccag
      241 gaacggcccc cagactcctc atctatgaaa ataataaacg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct gatacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cctgagtgtc gtgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01000861             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:23166:7522
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000861
VERSION     KCVO01000861.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:23166:7522"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72890.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           97 a          143 c          121 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggtaccagca gaaaccaggc cagtccccta tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgaaaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacaacagtg gtcagggctc attcggagga gggaccctgc tgaccgtcct
      421 aggtcagccc aaggctgcct cctcggtcac tctcttcccg
//
LOCUS       KCVO01000862             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:16040:7245
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000862
VERSION     KCVO01000862.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16040:7245"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..435
                     /note="immunoglobulin light chain variable region"
     V_region        91..435
     V_segment       91..400
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72891.1"
                     /translation="DYYSMIWHNNVWVF"
     J_segment       401..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>474
                     /gene="IGLC"
BASE COUNT           93 a          154 c          116 g          111 t
ORIGIN      
        1 acatgggggg cggggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcg cagcctgtgc tgactcagcc accctccctc
      121 tcagcatctc ctggagcatc agccagactc acctgcacct tgcgcagtgg catcagtgtt
      181 ggtagttaca ggatattctg gtaccagcag aagccaggga gtcctccccg gtatcttctg
      241 aactaccaca cagactcaga taaacaccag ggatctggag tccccagccg cttctctgga
      301 tccaaagatg cttcggccaa tgcagggatt ttactcatct ctgggctcca gtctgacgat
      361 gaggctgact attactctat gatttggcac aacaatgttt gggtattcgg cggagggacc
      421 cggctgaccg tcctaagtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000863             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:14198:8565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000863
VERSION     KCVO01000863.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:14198:8565"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..395
                     /gene="IGLV10-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72892.1"
                     /translation="DYYCSAWDSSLSVVLF"
     J_segment       401..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT          105 a          157 c          126 g           84 t
ORIGIN      
        1 acatggggaa agcagagctt cggcaagcac agggggaatc cgcaccatgc cctgggctct
       61 gctcctcctg accctcctca ctcactctgc agtgccagtg gtccaggcag ggctgactca
      121 gccaccctca gtgtccaagg gcttgagaca gacggccacg ctcacctgca ctggaaacag
      181 caacaatgtt ggcaaccagg gagcaggttg gctgcagcag caccagggcc accctcccaa
      241 actgctgtcc tacaggaata acaaccggcc ctcggggatc tcagagagat tctctgcatc
      301 caggtcagga aacacagcct ccctgaccat caccggactc caacctgagg atgaggctga
      361 ctattactgc tcagcatggg acagcagcct cagtgttgtt ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000864             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:8511:22139
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000864
VERSION     KCVO01000864.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8511:22139"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..388
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72893.1"
                     /translation="DYYCQVWDSSSNVFF"
     J_segment       396..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          139 c          139 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagattctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcattggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttgtactgg
      241 tcatctatgc tgatagggaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtaatg tatttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000865             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:19756:12444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000865
VERSION     KCVO01000865.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:19756:12444"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..426
                     /note="immunoglobulin light chain variable region"
     V_region        99..426
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72894.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          145 c          124 g          102 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 caaaaaaatt tgcttcttgg ttccagcaga agccaggcca gtcccctgtg ctgatcatct
      241 atgacgacag caaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc attggggccc aggtggagga tgaagctgac taccactgtt
      361 tctcaacaga tagcagtggt aatcataggg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000866             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:10804:11011
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000866
VERSION     KCVO01000866.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10804:11011"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..389
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72895.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          152 c          121 g          103 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac gcagccgccc
      121 tcagtgtctg gggcgcccgg gcagagggtc accatctcct gcactgggag cagctccaac
      181 attggaggtt attatgtgca gtggtaccag cagcttccag gaacggcccc caaactcctc
      241 atatatgaaa ataataagcg accctcaggg gtttctgatc gattctctgg ctcccagtct
      301 ggtacctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgattattac
      361 tgccagtcct atgacagcag cctgagtgcc gtgttattcg gagcagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000867             333 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:16768:2817
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000867
VERSION     KCVO01000867.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 333)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16768:2817"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    73..295
                     /note="immunoglobulin light chain variable region"
     V_region        73..295
     V_segment       73..255
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <217..>267
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72896.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       259..295
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        296..>333
                     /gene="IGLC"
BASE COUNT           67 a          104 c           88 g           74 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacagcagaa ggcaggccag tcccctgtgc tgatcatcta tgaggacagc
      121 aaacggccct ctgggatccc tgagagattc tctggctcca gttcagggac aatggccacc
      181 ttgactatca gtggggccca ggtggaggat gaagctgact actactgtta ctcaacagat
      241 aacagtgata ctcatagggg cttcttcgga ggagggaccc ggctgaccgt cctaggtcag
      301 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000868             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:19898:10954
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000868
VERSION     KCVO01000868.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19898:10954"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..392
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72897.1"
                     /translation="DYFCQSYDSRLSAVLF"
     J_segment       394..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          149 c          124 g          107 t
ORIGIN      
        1 acatgggggg cacaggaggc agcactcagg acagtctcca gcatggcctg gtctcctctc
       61 ctcctcaccc ttctcattca ctgcacaggg tcctgggccc agtctgtgct gacgcagccg
      121 ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct cctgcactgg gagcagctcc
      181 aacattggag attattatgt gcagtggtac cagcagtttc caggaacggc ccccaaattt
      241 ctcatctatg aaaataataa gcgaccctca ggggtttctg atcgattctc tggctcccag
      301 tctggtacct cagcctccct gaccatcact ggactccagt ctgaggatga ggctgattat
      361 ttctgccagt cctatgacag caggctgagt gccgtgttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000869             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:18164:3973
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000869
VERSION     KCVO01000869.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18164:3973"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72898.1"
                     /translation="DYYCQVWDITTDHDVF"
     J_segment       389..425
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           94 a          137 c          130 g          102 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatgacct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ttctgcggcc tcctatgagc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacgacat
      181 tggaagtaaa aatgttcact ggtaccagca gaagccaccg caggcccctg tattggtcat
      241 ctattatgat agcaaacggc cctcagggat ccctgagcga ttctctggcg ccaaatcagg
      301 gaacaccgcc accctgatca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattacta ctgatcatga tgtgttcgga agtggcacca agttgaccgt
      421 cctcggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01000870             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:8979:11140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000870
VERSION     KCVO01000870.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:8979:11140"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72899.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          144 c          138 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctcactc
      121 agccaccctc ggtgtcagtg tccccaggac agacgaccag gatcacctgt gggggaggca
      181 atgttggaag tgaatatgtc cactggtatc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatctgtta taatactgac cggccctcag ggatccctga ccgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt aggagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000871             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:12976:8778
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000871
VERSION     KCVO01000871.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12976:8778"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..432
                     /note="immunoglobulin light chain variable region"
     V_region        102..432
     V_segment       102..395
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72900.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       396..432
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           93 a          156 c          118 g          103 t
ORIGIN      
        1 acatgggggg ggtacagaag gcaggactca ggacaatctc cagcatggcc tggttccctc
       61 tcctcctcac cctcctcact cactgtgcag ggtcctgggc ccagtctgtg ctgactcagc
      121 ctccctcagc gtctgaggcc gccaggaaga gtgtcaccat ctcctgttct ggaagcacct
      181 ccaacatcgg aactaatagt gtatcctggt accagcagct cccagaaacg gctcccaaac
      241 tcctcatcta ttataatgat cgacgagcct caggtgtctc tgaccgattc tctggctcca
      301 agtctggcac gtcagcctcc ctggccatca gtgggctcca gaccgaggat gaggctgatt
      361 attactgcgc agcatgggat aacagcctga gcggttacat cttcggtgct gggacccggc
      421 tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01000872             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:19359:11321
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000872
VERSION     KCVO01000872.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19359:11321"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72901.1"
                     /translation="DYYCSAWDDSLSSPLF"
     J_segment       393..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          153 c          114 g          106 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag caactccaac
      181 attggaagta attatgtaaa ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 atctatttta gtaatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgttcagcat gggatgacag cctgagcagt cccttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000873             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:12506:13282
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000873
VERSION     KCVO01000873.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12506:13282"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..380
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72902.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       384..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           96 a          144 c          122 g           96 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcgttgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 cagaaaaata tgcttattgg taccagcaga aaccaggcca gtcccctatg ctgatcatct
      241 gtgaggacag caaacggccc tctgggatcc ctgaaagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc actggggccc aggtggagga tgaagctgac tactactgtt
      361 actcagcaga caacagtggt cagggctcat tcggaggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000874             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:24118:8023
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000874
VERSION     KCVO01000874.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:24118:8023"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72903.1"
                     /translation="DYYCQVWDSSNKYVFF"
     J_segment       399..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           91 a          143 c          133 g          100 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca caggctctgt ggcctcctat gagctgactc
      121 agccaccctc ggtgtcggag tccccaggac agacagccag gatcacctgt gggggagaca
      181 tacttggagg tcaaagtgta cactggtacc aacagaagcc accgcaggcc cctgtgttgg
      241 tcttgtatgc tgataacgaa cggccctcag ggatccctga ccgattctct gtctccaatt
      301 cagggaatac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt ctgggacagt agtaataaat atgtattttt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000875             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:8432:14644
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000875
VERSION     KCVO01000875.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:8432:14644"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72904.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       413..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           91 a          157 c          129 g          110 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcaccatctc
      181 ctgcactggg agcagttcca acattggagg ttattatgtg cagtggtacc agcagcttcc
      241 aggaacggcc cccaaactcc tcatgtatga aaataataag cgaccctcag gggtttctga
      301 tcgattctct ggctcccagt ctggtacctc agcctccctg accatcactg gactccagtc
      361 tgaggatgag gctgattatt actgccagtc ctatgacagc agcctgagtg ccgtgttatt
      421 cggagcaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCVO01000876             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:18200:10321
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000876
VERSION     KCVO01000876.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18200:10321"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72905.1"
                     /translation="DYYCGAWDSGLSARLF"
     J_segment       412..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          156 c          131 g          109 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggaccccgg gcagagggtc accatctcgt
      181 gcactgggag cagctccaac attggaggtt attttgtata ctggtatcag cagttcccag
      241 gaacagcccc caaactcctc atctatgaca ataataagcg accctcaggg atttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagcctg
      361 gggatgaggc tgattattac tgcggagcat gggatagcgg cctgagtgct cgcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01000877             330 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:14159:7212
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000877
VERSION     KCVO01000877.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 330)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 330)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..330
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14159:7212"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..292
                     /note="immunoglobulin light chain variable region"
     V_region        8..292
     V_segment       8..255
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <217..>264
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72906.1"
                     /translation="DYYCQVWDSSSDHPIF"
     J_segment       258..292
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        293..>330
                     /gene="IGLC"
BASE COUNT           67 a           95 c           98 g           70 t
ORIGIN      
        1 acatgggcag gacggacggc caggatcacc tgtgggggag acatcgttgg aaatgaatat
       61 gttcactggt atcagcagaa gtcaacgcag gcccctgtgg tggtcatcta ttattattct
      121 gaccggccct cagggatccc tgagcgattc tctggctcca aatcagggag caccgccacc
      181 ctgaccatca gcggggtcga ggccggggat gaggctgact actactgtca ggtgtgggac
      241 agtagtagtg atcatcccat cttcggtgct gggacccggc tcaccgtcct aggtcagccc
      301 aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01000878             331 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:12800:5773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000878
VERSION     KCVO01000878.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 331)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 331)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12800:5773"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..292
                     /note="immunoglobulin light chain variable region"
     V_region        5..292
     V_segment       5..255
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <218..>265
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72907.1"
                     /translation="DYYCQSYDGSLSAVLF"
     J_segment       257..292
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        293..>331
                     /gene="IGLC"
BASE COUNT           71 a          101 c           81 g           78 t
ORIGIN      
        1 acatggacag agggtcacca tctcctgcac tgggagcagc tccaacattg gaacttatta
       61 tgtgcagtgg taccagcaac ttccaggaac ggcccccaaa gttctcatct ctgaaaataa
      121 taagcgaccc ttaggggttt ctgatcgatt ctctggctcc cagtctggta cctcagcctc
      181 cctgaccatc actggactcc agtctgagga tgaggctgat tattactgcc agtcctatga
      241 cggcagcctg agtgccgtgt tattcggagg agggacccgg ctgaccgtcc taagtcagcc
      301 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000879             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:16309:2652
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000879
VERSION     KCVO01000879.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:16309:2652"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72908.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       402..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           87 a          156 c          123 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcagtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacacaag cagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000880             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:13983:14445
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000880
VERSION     KCVO01000880.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:13983:14445"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72909.1"
                     /translation="DYYCAAWDDSLSSPLF"
     J_segment       409..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           92 a          153 c          122 g          114 t
ORIGIN      
        1 acatggggac cttcagctgc gggtacagaa ggtaggactc aggataatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag ccaccctcaa cgtctggggc tcccgggcag agtgtcacca tctcttgctc
      181 tggaagcagt ttcaacattg gaagtaatta tgtaaactgg taccagcagc tcccaggaac
      241 ggcccccaaa ctcctcatct attttagtaa tcagcggccc tcaggggtcc ctgaccgatt
      301 ctctggctct aagtctggca cctcagcctc cctggccatc actggtctcc gatctgagga
      361 tgaggctgat tattactgtg cagcatggga tgatagtctg agcagtccct tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01000881             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:19340:17259
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000881
VERSION     KCVO01000881.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:19340:17259"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72910.1"
                     /translation="DYYCSSYTSSSTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          158 c          122 g          108 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttctg aggtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct ggactccagg ctgaggacga
      361 ggctgattat tactgcagct catacacaag cagtagcact tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000882             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:16014:15412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000882
VERSION     KCVO01000882.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16014:15412"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72911.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           84 a          162 c          119 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgacaca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc ctttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa caccacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac ttccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000883             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:10353:18413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000883
VERSION     KCVO01000883.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10353:18413"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72912.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           94 a          142 c          124 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgagaga atctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtagag gatgaagctg actactactg
      361 ttcctcaaca gatagtagtg gtaatcatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000884             416 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:18825:10434
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000884
VERSION     KCVO01000884.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 416)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 416)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18825:10434"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..378
                     /note="immunoglobulin light chain variable region"
     V_region        97..378
     V_segment       97..338
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <300..>350
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72913.1"
                     /translation="DYYCQSYDSSLNPHVLF"
     J_segment       341..378
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        379..>416
                     /gene="IGLC"
BASE COUNT           85 a          136 c           94 g          101 t
ORIGIN      
        1 acatggggga gctctgcttc atctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctcg tctcctctcc tcctcaccct tctcattcac catctcctgc actgggaaca
      121 actccaacat tggaggttat tatgtatatt ggtaccagca actcccagga atggccccca
      181 cactcctcat ctatgacaat aataagcgac cctcaggggt ttctgaccga ttctctggct
      241 ccaagtctgg ttcctcagcc tccctgacca tcactgggct ccagactgag gatgaggctg
      301 attattactg ccagtcctat gacagcagcc tgaatcctca tgtgttattc ggaggaggga
      361 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000885             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:25551:10628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000885
VERSION     KCVO01000885.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:25551:10628"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72914.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          143 c          126 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc tcctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaaggcaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagttcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gataacagtg atactcatag gggcttcttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000886             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:11083:15014
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000886
VERSION     KCVO01000886.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:11083:15014"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72915.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           85 a          155 c          124 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttgtgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000887             455 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:11406:15554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000887
VERSION     KCVO01000887.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 455)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 455)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:11406:15554"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..417
                     /note="immunoglobulin light chain variable region"
     V_region        99..417
     V_segment       99..381
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>389
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72916.1"
                     /translation="DYYCYSEDSRSSIF"
     J_segment       383..417
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>455
                     /gene="IGLC"
BASE COUNT           94 a          142 c          122 g           97 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcgttgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 cagaaaaata tgcttattgg taccagcaga aaccaggcca gtcccctgtg ctgatcatct
      241 atgaggacag caaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc agtggggccc aggtggagga tgaagctgac tactactgtt
      361 actcagagga cagcaggagt agcatcttcg gtgctgggac ccggctcacc gtcctaggtc
      421 agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCVO01000888             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:9262:5244
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000888
VERSION     KCVO01000888.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:9262:5244"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..423
                     /note="immunoglobulin light chain variable region"
     V_region        105..423
     V_segment       105..386
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <354..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72917.1"
                     /translation="DYYCQSTDSSGYIF"
     J_segment       387..423
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT          102 a          135 c          120 g          104 t
ORIGIN      
        1 acatgggggg ctgtggttct aggaggaaga gctctgggtg tctcaccatg acctggacca
       61 ctgttctgct cccctttctc actctctgca caggctctgt ggcctcctat gagctgacac
      121 agccaccctc agtgtcagtg tccccaggac agacggccag gatcacctgc tctggagaaa
      181 tactgacaaa aaattatgct cagtggttcc agcagaagcc aggccaggcc cctgtgctgc
      241 tgatatataa agacagtgag aggccctcag ggatccctga gcgattctct agttccagtt
      301 cagggacaac agttaccttg accatcagtc gggcccaggt agaagatgag gctgactatt
      361 attgtcaatc aacagacagc agtggttaca tcttcggtgc tgggacccgg ctcaccgtcc
      421 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCVO01000889             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:17224:15031
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000889
VERSION     KCVO01000889.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17224:15031"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72918.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       402..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           87 a          156 c          123 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaagtc atgatttatg aggtcagtaa tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctgccaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacacaag cagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000890             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:10712:17341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000890
VERSION     KCVO01000890.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:10712:17341"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72919.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          144 c          137 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctac ggtctccttt gacctcactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggaggca
      181 atgttggaag tgaatatgtc cactggtatc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatctatta taatactgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt aggagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000891             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:15616:23760
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000891
VERSION     KCVO01000891.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:15616:23760"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..449
                     /note="immunoglobulin light chain variable region"
     V_region        116..449
     V_segment       116..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72920.1"
                     /translation="DYYCQSYDSSLSPHVLF"
     J_segment       412..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           94 a          160 c          122 g          111 t
ORIGIN      
        1 acatggggct ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct cctctcctcc tcacccttct cattcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct caatgtctgg ggcgcccggg cagagggtca ccatctcctg
      181 cactgggagc agctccaaca ttggagatta ttatgtgcag tggtaccagc agcttccagg
      241 aacggccccc aaactcctca tctatgaaaa taataagcga ccctcaggga tttctgatcg
      301 attctctggc tcccagtctg ctacctcagc ctccctaacc atcactggac tccagtctga
      361 ggatgaggct gattattact gccagtccta tgacagcagc ctgagtcctc atgtgttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCVO01000892             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:27306:15013
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000892
VERSION     KCVO01000892.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:27306:15013"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..397
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72921.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       398..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           83 a          152 c          123 g          113 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcactct caggacgtct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 tctccctctg tgtctgggtc tcctggacag tcggtcacca tttcctgcac tggaaccagc
      181 agtgacattg gtggttttga gcgtgtctcc tggtaccaac agcacccagg caaagccccc
      241 aaactcttga tttatgaggt cagttatcgg ccctcagggg tctctgatcg cttctctggt
      301 tccaagtctg ccaacacggc ctccctgatc atctctgggc tccaggctga ggacgaggct
      361 gattattatt gcagctcata cacaagtagt agtacttggg tattcggcgg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000893             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:20117:18059
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000893
VERSION     KCVO01000893.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20117:18059"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72922.1"
                     /translation="DYYCQVWDSSTNHILF"
     J_segment       396..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          147 c          135 g           97 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acaggctctg cggtctccta tgagctgact
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 aaccttgcag atgaatatgt acactggtac cagcagaagc cagcgcgggc ccctttactg
      241 gtcatctact atgatagtga ccggccctca tggatccctg agcgattctc tgggtccaaa
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag tagtactaat catatcttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000894             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:16821:17775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000894
VERSION     KCVO01000894.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16821:17775"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..403
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72923.1"
                     /translation="DYYCCSYTTSSTFIF"
     J_segment       404..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          154 c          117 g          116 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcttggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtccg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgat attgggtatt ataatactgt gtcttggtac caacagcacc caggcacagc
      241 ccccaaagtc atgatttatg gtgtcagtaa tcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgttgtt catatacaac cagtagcact ttcatcttcg gtgatgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCVO01000895             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:20049:8338
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000895
VERSION     KCVO01000895.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:20049:8338"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72924.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           97 a          144 c          122 g           97 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggtaccagca gaaaccaggc cagtccccta tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgaaaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacaacagtg gtcagggctc attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000896             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:20058:15612
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000896
VERSION     KCVO01000896.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20058:15612"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..419
                     /note="immunoglobulin light chain variable region"
     V_region        98..419
     V_segment       98..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <347..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72925.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       386..419
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT           91 a          142 c          124 g          100 t
ORIGIN      
        1 acatgggggg ctcaggaggc agagctctgg gtgtctcacc atggcctgga ttcctctcct
       61 actccccctc ctcactttct gcacaggctc tgcagcctcc tatgagctga cacagccacc
      121 ctcggtgtca gtgtccccag gacagacggc caggatcacc tgctctggag atgcattgcc
      181 agaaaaatat gcttattggt tccagcagaa gccaggccag tcccctgtgc tgatcatcaa
      241 tgaggacagc aaacggccct ctgggatccc tgggagattc tctggctcca gctcagggac
      301 agtggccacc ttgactctca gtggggccca ggtggaggat gaagctgact actactgttc
      361 ctcaacagat agtagtggta attatgtatt cggcggaggg acccggctga ccgtcctagg
      421 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000897             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:20776:16286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000897
VERSION     KCVO01000897.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:20776:16286"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72926.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       398..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          143 c          139 g           97 t
ORIGIN      
        1 acatggggct gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acagactctg cggtctccta tgacctgact
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 aatgttggaa gtgaatatgt gcactggtac caacagaaac cagcgcaggc ccctgtggtg
      241 gtcatccatt ataatagtga ccggccctca gggatccctg agcgattctc tggctccaaa
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag tagtagtgat cattgtgtat tgggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01000898             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:11870:21456
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000898
VERSION     KCVO01000898.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:11870:21456"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72927.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          163 c          119 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc ctttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa caccacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgctc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac ttccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000899             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:21664:9798
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000899
VERSION     KCVO01000899.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:21664:9798"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..422
                     /note="immunoglobulin light chain variable region"
     V_region        100..422
     V_segment       100..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72928.1"
                     /translation="DYYCYSSDISGNHRVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>462
                     /gene="IGLC"
BASE COUNT           94 a          139 c          123 g          106 t
ORIGIN      
        1 acatggggtg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactccccc tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agatgcattg
      181 ccaaaaaaat atgcttattg gttccagcag aagccaggcc agtcccctgt gttgatcatc
      241 tatgaagaca gtaaacggcc ctctgggatc cctgagagat tctctggctc cacttcaggg
      301 acagtggcca ccttgactat tagtggggcc caggtggagg atgaagctga ctactactgt
      361 tactcatcag atatcagtgg gaatcatagg gtattcggcg gagggacccg gctgaccgtc
      421 cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000900             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:25229:17167
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000900
VERSION     KCVO01000900.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:25229:17167"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72929.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          142 c          139 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gtgggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga acgattctct ggctccaaat
      301 cagggagcgc cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc atagtttatt gggaggaggg acccggttga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000901             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:11999:6396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000901
VERSION     KCVO01000901.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:11999:6396"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72930.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       397..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           91 a          142 c          138 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagactctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaaacc agcgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag actgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgtgtatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000902             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:7923:3830
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000902
VERSION     KCVO01000902.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7923:3830"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72931.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           85 a          155 c          124 g          109 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtaatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacgcaagca gtagcacttg ggttttcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000903             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:22677:15041
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000903
VERSION     KCVO01000903.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22677:15041"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72932.1"
                     /translation="DYYCSSYTSTTTWPF"
     J_segment       403..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          161 c          119 g          106 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcac taccacttgg ccattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000904             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:12797:4943
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000904
VERSION     KCVO01000904.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12797:4943"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72933.1"
                     /translation="DYYCAAWDDSLSSPLF"
     J_segment       393..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          150 c          117 g          108 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagcgtc accatctctt gctctggaag cagtttcaac
      181 attggaagta attatgtaaa ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 atctatttta gtaatcagcg gccctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcat gggatgatag tctgagcagt cccttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000905             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:14041:16214
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000905
VERSION     KCVO01000905.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14041:16214"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72934.1"
                     /translation="DYYCYSTDTSGDHRVF"
     J_segment       390..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          145 c          126 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttttt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac accaaacggc ccgctgggat ccctgagaga ttctctggct ccagctcagg
      301 cacagtggcc accttgactg tcactggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gataccagtg gtgatcatag ggtgttcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000906             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:27457:14238
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000906
VERSION     KCVO01000906.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:27457:14238"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    129..453
                     /note="immunoglobulin light chain variable region"
     V_region        129..453
     V_segment       129..416
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72935.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       421..453
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT          100 a          149 c          134 g          108 t
ORIGIN      
        1 acatggggag agaagcctag ggagcccagc tgtgctgtgg gctcaggagg cagagctctg
       61 ggtgtctcac catggcctgg attcctctcc tactccccct cctcactttc tgcacaggct
      121 ctgcagcctc ctatgagctg acacagccac cctcggtgtc agtgtcccca ggacagacgg
      181 ccaggatcac ctgctctgga gatgcattgc caaaaaagta tgcttattgg ttccagcaga
      241 agccaggcca gtcccctgtg ctgatcatct atgaagacga caaacggccc tctgggatcc
      301 ctgagagatt ctctggctcc agctcaggga cagtggccac cttgactatc agtggggccc
      361 aggtggagga tgaagctgac tactactgtt actcaataga tagtagtggt agtcatagcg
      421 tcttcggtgc tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca
      481 ctctgttccc g
//
LOCUS       KCVO01000907             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:10623:13448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000907
VERSION     KCVO01000907.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10623:13448"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..431
                     /note="immunoglobulin light chain variable region"
     V_region        107..431
     V_segment       107..397
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72936.1"
                     /translation="DYYCCSYAGTYLF"
     J_segment       398..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           84 a          157 c          122 g          106 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgtcctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggta ataattatgt ctcctggtac cagcaacatc caggcacagc
      241 ccccaaattc atcatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgctgct catatgcagg cacctactta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000908             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:16312:10963
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000908
VERSION     KCVO01000908.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16312:10963"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72937.1"
                     /translation="DYYCSSTDNSGNYVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          143 c          124 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gataacagtg gtaattatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000909             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:16719:14118
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000909
VERSION     KCVO01000909.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:16719:14118"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72938.1"
                     /translation="DYYCYSTRSSGYHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          142 c          125 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ctctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtgcag gatgaagctg actactactg
      361 ttactcaact cgtagcagtg gttatcatgg cttattcgga ggggggacct ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000910             301 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:11085:15240
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000910
VERSION     KCVO01000910.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 301)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 301)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11085:15240"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..260
                     /note="immunoglobulin light chain variable region"
     V_region        8..260
     V_segment       8..226
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <188..>235
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72939.1"
                     /translation="DYYCFSSDSSADYWVF"
     J_segment       227..260
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        261..>301
                     /gene="IGLC"
BASE COUNT           63 a           83 c           86 g           69 t
ORIGIN      
        1 acatggggga gatgcattgc cagaaaaata tgcttattgg ttccagcaga agccaggcca
       61 gtcccctgtg ttgatcatct atgaggacac caaacggccc tctgggatcc ctgagagatt
      121 ctctggttcc agctcaggga cagtggccac cttgactatc agtggggccc aggtggagga
      181 tgaagctgac tactactgtt tctcatcaga tagcagtgct gattattggg tgttcggcgg
      241 agggacccgg ctgaccgtcc caggtcagcc caaggctgcc ccctcggtca ctctcttccc
      301 g
//
LOCUS       KCVO01000911             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:25270:16312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000911
VERSION     KCVO01000911.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:25270:16312"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..394
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72940.1"
                     /translation="DYYCCSYAGRYLF"
     J_segment       395..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           82 a          156 c          125 g          103 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttcta actatgtctc ctggtaccaa cagtatccag gcacagcccc
      241 caaactcatg atttatgagg tcagtaagcg gccctcaggg gtctcgagtc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgctgctcat atgcaggcag gtacttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000912             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:9250:9623
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000912
VERSION     KCVO01000912.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:9250:9623"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..424
                     /note="immunoglobulin light chain variable region"
     V_region        105..424
     V_segment       105..392
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72941.1"
                     /translation="DYYCHSLDTSGNDVF"
     J_segment       396..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>464
                     /gene="IGLC"
BASE COUNT           90 a          144 c          128 g          102 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccctcctc actttctgca caggctctgc agcctcctat gagctgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg
      181 cactgccaaa aaaatttgct tactggttcc agcagaagcc aggccagtcc cctgtggcga
      241 tcatctatga ggacagcaaa cggccctctg ggatccctga gagattctct ggctccagct
      301 cagggacagt ggccaccttg actatcagtg gggcccaggt ggaggatgaa gctgactact
      361 actgtcattc attagatacc agtggtaatg atgttttcgg cggagggacc cggctgaccg
      421 tcctgggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000913             495 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:23842:16702
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000913
VERSION     KCVO01000913.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 495)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23842:16702"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..457
                     /note="immunoglobulin light chain variable region"
     V_region        130..457
     V_segment       130..417
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>429
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72942.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       421..457
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        458..>495
                     /gene="IGLC"
BASE COUNT          101 a          150 c          135 g          109 t
ORIGIN      
        1 acatggggaa gagaagccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactccccc tcctcacttt ctgcacaggc
      121 tctgcagcct cctatgagct gacacagcct ccctcggtgt cagtgtcccc aggacagacg
      181 gccaggatct cctgctctgg agatgcattg ccaaaaaaat ttgcttcttg gttccagcag
      241 aaggcaggcc agtcccctgt gctgatcatc tatgaggaca gcaaacggcc ctctgggatc
      301 cctgagagat tctctggctc cagttcaggg acaatggcca ccttgactat cagtggggcc
      361 caggtggagg atgaagctga ctactactgt tactcaacag ataacagtga tactcatagg
      421 ggcttcttcg gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg
      481 gtcactctct tcccg
//
LOCUS       KCVO01000914             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:25575:10175
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000914
VERSION     KCVO01000914.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:25575:10175"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72943.1"
                     /translation="DYYCGSCTSGITYIF"
     J_segment       399..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           80 a          157 c          126 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcgggacgtc tccaccatgg cttgggctct
       61 ggtcctcctc accctcctca ctcagggcac aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggagccag
      181 cggtgacatt ggtggttata acggtgtctc ctggtaccag cagcactcag gcacagcccc
      241 cagactcctg atttatgagg tcactaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcggctcat gtacgagtgg aatcacttac atcttcggtg ctgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01000915             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:21658:3382
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000915
VERSION     KCVO01000915.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:21658:3382"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72944.1"
                     /translation="DYYCSSYTSSSTWIF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           87 a          155 c          122 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagcacttgg atattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000916             346 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:15943:18048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000916
VERSION     KCVO01000916.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 346)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 346)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..346
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15943:18048"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..308
                     /note="immunoglobulin light chain variable region"
     V_region        4..308
     V_segment       4..272
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <236..>280
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72945.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       273..308
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        309..>346
                     /gene="IGLC"
BASE COUNT           65 a          114 c           86 g           81 t
ORIGIN      
        1 acatgggtct gggtctcctg gacagtcggt caccctttcc tgcactggaa ccagcagtga
       61 cattggtggt tataaccgtg tctcctggta ccaacaccac ccaggcaaag cccccaaact
      121 catgatttat gacgtcagtg atcggccctc aggggtctct gatcgcttct ctggttccaa
      181 gtctggcaac acggcctccc tgatcatctc tgggctccag gctgaggacg aggctgatta
      241 ttactgcagc tcatacgcaa gcacttccac ttggctattc ggcggaggga cccgcctgac
      301 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000917             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:17619:15561
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000917
VERSION     KCVO01000917.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:17619:15561"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..390
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72946.1"
                     /translation="DYYCLLYYSGAYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           98 a          156 c          111 g          100 t
ORIGIN      
        1 acatgggggg agccagagat cccttccaat accagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtggctc caacactgga
      181 gcagtcacca gtgactacta tccaaactgg ttccagcaga cacctggaca agtccccagg
      241 ggactgattt acaatacaaa caacaaacac tcctggaccc ctgcccggtt ctcaggctcc
      301 ctcgctgggg gcaaagctgc cctgacactg tcagatgcac agcccgagga cgaggctgac
      361 tattactgtt tgctgtacta tagtggtgct tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCVO01000918             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:12082:8074
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000918
VERSION     KCVO01000918.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12082:8074"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..399
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72947.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       402..438
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           89 a          160 c          121 g          106 t
ORIGIN      
        1 acatgggggt ggcctcagag gtagccgtgt ccaccatggc cctgactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgactcag ccaccctccc
      121 tgtctgcatc cccgggagca tcggccagac tcccctgcac cctgagcagt gacctcagtg
      181 ttggtagtaa aaacatatac tggtaccagc agaagccagg gagcgctccc aggttattcc
      241 tgtactacta ctccgactca gacaagcagc tgggacctgg ggtccccaat cgagtctctg
      301 gctccaagga gacctcaagt aacacagcgt ttttgctcat ctctgggctc cagcctgagg
      361 acgaggccga ttattactgt caggtgtatg acagtactgg agtgttgttc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000919             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:23756:10142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000919
VERSION     KCVO01000919.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:23756:10142"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72948.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       393..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          144 c          127 g          103 t
ORIGIN      
        1 acatgggggt gtgggctcag gaggcagagc tctgggtgtc tcaccatggc ctggattcct
       61 ctcctactcc ccctcctcac tttctgcaca ggctctgcag cctcctatga gctgacacag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgctc tggagatgca
      181 ttgccaaaaa agtatgctta ttggttccag cagaagccag gccagtcccc tgtgctgatc
      241 atctatgagg acagcagacg gccctctggg atccctgaga gattctctgc ctccagctca
      301 gggacagtgg ccaccttgac tatcagtggg gcccaggggg aggatgaagc tgactactac
      361 tgttattcaa tggatagcag tggtactcag agcatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCVO01000920             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:20357:22579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000920
VERSION     KCVO01000920.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20357:22579"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..384
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72949.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       388..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           96 a          145 c          123 g           98 t
ORIGIN      
        1 acatggggct gtgggctcag gaggcagagc tctgggtgtc tcaccatggc ctggattcct
       61 ctcctactcc ccatcctcac tttctgcaca ggctctgcag cctcctatga gctgacacag
      121 ccaccctcgt tgtcagtgtc cccaggacag acggccagga tcacctgctc tggagatgca
      181 ttgccagaaa aatatgctta ttggtaccag cagaaaccag gccagtcccc tatgctgatc
      241 atctgtgagg acagcaaacg gccctctggg atccctgaaa gattctctgg ctccagctca
      301 gggacagtgg ccaccttgac tatcactggg gcccaggtgg aggatgaagc tgactactac
      361 tgttactcag cagacaacag tggtcagggc tcattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000921             299 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:24281:7604
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000921
VERSION     KCVO01000921.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 299)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:24281:7604"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..261
                     /note="immunoglobulin light chain variable region"
     V_region        6..261
     V_segment       6..224
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <186..>233
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72950.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       225..261
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        262..>299
                     /gene="IGLC"
BASE COUNT           69 a           84 c           81 g           65 t
ORIGIN      
        1 acatgggaga tgcattgcca aaatactatg cttattggtt ccagcagaag ccaggccagt
       61 cccctgtggc gatcatctat gaggacaaca aacggccctc tgggatccct gagagattct
      121 ctggctccag ctcagggaca gtggccacct tgactatcag tggggcccag gtagaggatg
      181 aagctgacta ctactgttac tcaacagata gcagtggtac taatggctta ttcggaggag
      241 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000922             566 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:13041:4580
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000922
VERSION     KCVO01000922.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 566)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 566)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..566
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13041:4580"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    204..528
                     /note="immunoglobulin light chain variable region"
     V_region        204..528
     V_segment       204..491
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <453..>500
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72951.1"
                     /translation="DYYCQVWDSSSKYAIF"
     J_segment       496..528
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        529..>566
                     /gene="IGLC"
BASE COUNT          115 a          180 c          161 g          110 t
ORIGIN      
        1 acatggggac agatctcctc cagcagcagc cgctgactct gctgatttgc atcatgggcc
       61 actctctcca gtaagaggat aagagaagcc tggaaggcac ctgccctgtc tgggtctcag
      121 gaggcagcat tgacggtgcc tcagccatgg cctggaccct tctcctcctc ggcctcctcg
      181 ctcactgcac aggctctgcg acctcctatg aggtgactca gccaccctcg gtgtcagcgg
      241 cctcaggaca gacggccagg atcacctgtg ggggagacaa cattggaagt agaaatgtcc
      301 actggtacca gcagaagcca ccgcaggccc ctgttctggt catctatgct gatgccaaac
      361 ggccctcagg gatccctgag cgattctctg gctccaactc agggaacacc gccaccctga
      421 ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta ctgtcaggtg tgggacagta
      481 gtagtaaata cgcgatattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      541 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000923             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:7293:3251
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000923
VERSION     KCVO01000923.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:7293:3251"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72952.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          142 c          139 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggtcag gatcacctgt gtgggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga acgattctct ggctccaaat
      301 cagggagcgc cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000924             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:17224:9098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000924
VERSION     KCVO01000924.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:17224:9098"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72953.1"
                     /translation="DYYCQVWDSTSKCILF"
     J_segment       394..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          143 c          134 g           95 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagataat
      181 attggaagta aaaatgtgca ctggtaccag cagaagccag cgcaggcccc tgtgttggtc
      241 atctgtgctg ataataaacg gccctcaggg atccctgagc gaatctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacagtac tagtaaatgc attttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000925             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:8185:6678
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000925
VERSION     KCVO01000925.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8185:6678"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72954.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          154 c          123 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagtacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000926             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:12474:5424
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000926
VERSION     KCVO01000926.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12474:5424"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72955.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          156 c          128 g          110 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcac catctcctgc
      181 actgggagca gttccaacat tggaggttat tatgtgcagt ggtaccagca gcttccagga
      241 acggccccca aactcctcat gtatgaaaat aataagcgac cctcaggggt ttctgatcga
      301 ttctctggct cccagtctgg tacctcagcc tccctgacca tcactggact ccagtctgag
      361 gatgaggctg attattactg ccagtcctat gacagcagcc tgagtgccgt gttattcgga
      421 gcagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01000927             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:20168:4977
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000927
VERSION     KCVO01000927.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20168:4977"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72956.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           94 a          146 c          124 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgacgac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accatgacta tcattggggc ccaggtggac gatgaagctg actaccactg
      361 tttctcaaca gatagcagtg gtaatcatag gggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000928             495 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:22838:8472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000928
VERSION     KCVO01000928.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 495)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:22838:8472"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..457
                     /note="immunoglobulin light chain variable region"
     V_region        130..457
     V_segment       130..417
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>429
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72957.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       421..457
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        458..>495
                     /gene="IGLC"
BASE COUNT          100 a          150 c          138 g          107 t
ORIGIN      
        1 acatggggaa gagaagccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactccccc tcctcacttt ctgcacaggc
      121 tctgcagcct cctatgagct gacacagcca ccctcggtgt cagtgtcccc aggacagacg
      181 gccaggatct cctgctctgg agatggattg ccaaaaaaat ttgcttcttg gttccagcag
      241 aaggcaggcc agtcccctgt gctgatcatc tatgaggaca gcaaacggcc ctctgggatc
      301 cctgagagat tctctggctc cagttcaggg acagtggcca ccttgactat cggtggggcc
      361 caggtggagg atgaagctga ctactactgt tactcaacag ataacagcga tactcatagg
      421 ggcttcttcg gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg
      481 gtcactctct tcccg
//
LOCUS       KCVO01000929             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:19710:13061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000929
VERSION     KCVO01000929.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19710:13061"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..443
                     /note="immunoglobulin light chain variable region"
     V_region        110..443
     V_segment       110..403
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72958.1"
                     /translation="DYYCSLWDSRLSSRVF"
     J_segment       408..443
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           92 a          153 c          128 g          108 t
ORIGIN      
        1 acatgggggg cttcagctgt gggcacagga ggcagcactc aggacagtct ccagcatggc
       61 ctggtctctc cttctcactc tgctggttca ctgcacaggg tcctgggccc agtctgtgct
      121 gacgcagccg ccctcagcat ctggggcccc cgggcagagg gtcaccatct cctgcactgg
      181 gaccagctcc aacatcgggg cgaattatta tgtttcctgg taccagcagt tcccaggaac
      241 agcccccaaa ctcctcatct atgaaaataa taagcgaccc tcaggggttt ctgaccgatt
      301 ctctggctcc aagtctggta cctcagcctc cctgaccatc tctggactcc aatctgagga
      361 tgaggctgat tattattgct cactatggga tagcaggctg agtagtcggg tattcggcgg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01000930             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:12923:4905
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000930
VERSION     KCVO01000930.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12923:4905"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72959.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          143 c          133 g           99 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgac ctcactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtgtg ggaggcaatg
      181 ttggaagtga atatgtccac tggtatcaac agaagccacc gcaggcccct gttatagtca
      241 tctattataa tactgaccgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagg agtgatcata gtttattggg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000931             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:19153:7328
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000931
VERSION     KCVO01000931.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19153:7328"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72960.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       395..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          143 c          124 g          105 t
ORIGIN      
        1 acatggggct gtgggctcag gaggcagagc tctgggtgtc tcaccatggc ctggattcct
       61 ctcctactcc ccctcctcac tttctgcaca ggctctgcag cctcctatga gctgacacag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgctc tggagatgca
      181 ttgccaaaaa agtatgctta ttggttccag cagaagccag gccagtcccc tgtgctgatc
      241 atctatgaag acgacaaacg gccctctggg atccctgaga gattctctgg ctccagctca
      301 gggacagtgg ccaccttgac tatcagtggg gcccaggtgg aggatgaagc tgactactac
      361 tgttactcaa tagatagtag tggtagtcat agcgtcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCVO01000932             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:20070:8910
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000932
VERSION     KCVO01000932.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20070:8910"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72961.1"
                     /translation="DYYYYSSDSSADYWVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           91 a          141 c          127 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggtt ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactacta
      361 ttactcatca gatagcagtg ctgattattg ggtgttcggc ggagggaccc ggctgaccgt
      421 cccaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000933             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:13185:4766
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000933
VERSION     KCVO01000933.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:13185:4766"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..381
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72962.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       384..421
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           86 a          137 c          139 g           97 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctgcacagat tctgtagtct cctatgaatt gactcagcca
      121 cgctcagtgt ccgtgtcccc aggacagacg gccaggatca cctgtggggg agacagcatt
      181 ggaagtagaa gtgtgcagtg gtaccagcag aagccaccgc aggcccttgt actggtcatc
      241 tatgctgata gggaacggcc ctcaggtatc cctgagcgat tctctggctc caatttaggg
      301 aacaccgcca ccctgaccat cagcggcgtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtagtag tgatgtgttg ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000934             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:12602:16012
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000934
VERSION     KCVO01000934.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:12602:16012"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72963.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       394..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           87 a          143 c          138 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggccaggctt ggcggtgcct cagccatggc cgggaccctt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg tctcctatga actcactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggaggcaat
      181 gttggaagtg aatatgtcca ctggtatcaa cagaagccac cgcaggcccc tgtggtggtc
      241 atctattata atactgaccg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag gagtgatcat agtttattgg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000935             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:8502:18620
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000935
VERSION     KCVO01000935.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8502:18620"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..395
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72964.1"
                     /translation="DYYCCSYAGSYLF"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           84 a          158 c          121 g          104 t
ORIGIN      
        1 acatggggtg gggtctcaga cggcagcgct ctcgggacat ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctcgctc agtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cggtggttat aactatgtct cctggtacca acaacatcca ggcacagccc
      241 ccaaactcat gatttatgag gtcagtaagc ggccctcagg ggtctctgat cgcttctctg
      301 cctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgctgctca tatgcaggca gctacttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000936             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:23924:12446
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000936
VERSION     KCVO01000936.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:23924:12446"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..423
                     /note="immunoglobulin light chain variable region"
     V_region        93..423
     V_segment       93..385
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72965.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       387..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           86 a          150 c          121 g          104 t
ORIGIN      
        1 acatggggga ggcagcactc aggacagtct ccagcatggc ctggtctcct ctcctcctca
       61 cccttctcat tcactgcaca gggtcctggg cccagtctgt gctgacgcag ccgccctcag
      121 tgtctggggc gcccgggcag agggtcacca tctcctgcac tgggagcagt tccaacattg
      181 gaggttatta tgtgcagtgg taccagcagc ttccaggaac ggcccccaaa ctcctcatgt
      241 atgaaaataa taagcgaccc tcaggggttt ctgatcgatt ctctggctcc cagtctggta
      301 cctcagcctc cctgaccatc actggactcc agtctgagga tgaggctgat tattactgcc
      361 agtcctatga cagcagcctg agtgccgtgt tattcggagc agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000937             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:21532:3289
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000937
VERSION     KCVO01000937.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:21532:3289"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72966.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           86 a          157 c          121 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcaggccac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattatc accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcaatgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000938             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:10635:14963
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000938
VERSION     KCVO01000938.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10635:14963"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    14..254
                     /note="immunoglobulin light chain variable region"
     V_region        14..254
     V_segment       14..217
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72967.1"
                     /translation="DYYCSSWDYNLSAGLF"
     J_segment       218..254
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>292
                     /gene="IGLC"
BASE COUNT           64 a           86 c           68 g           74 t
ORIGIN      
        1 acatgggatt ggaggttatt atgtatcttg gtaccagcaa ctcccaggaa cggtccccaa
       61 actcctcatc tatgaaaata ataagcgacc ctcagggatt tctgaccgat tctctggctc
      121 caagtctggt acctcagcct ccctaatcat cactggactc cagtctgagg atgaggctga
      181 ttattactgc tcttcatggg attacaacct gagtgctggc ctattcggag gagggacccg
      241 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000939             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:19677:11159
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000939
VERSION     KCVO01000939.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19677:11159"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72968.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       415..450
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           90 a          159 c          131 g          108 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggaccc cgggcagaag gtcaccatct
      181 cgtgcactgg gagcagctcc aacattggag gttattttgt gtactggtac cagcagttcc
      241 caggaacagc cccccaactc ctcatctatg acaataataa gcgaccctca gggatttctg
      301 accgattctc tggctccaag tctggtacct cagcctccct gaccatcact gggctccagc
      361 ctggggatga ggctgattat tactgcggcg catgggatag cagcctgagt gctcgcttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCVO01000940             425 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:23876:12200
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000940
VERSION     KCVO01000940.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 425)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:23876:12200"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    57..387
                     /note="immunoglobulin light chain variable region"
     V_region        57..387
     V_segment       57..352
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <315..>359
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72969.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       353..387
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        388..>425
                     /gene="IGLC"
BASE COUNT           76 a          140 c          104 g          105 t
ORIGIN      
        1 acatgggggc tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg
       61 ctgccctgac tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct
      121 gcactggaac cagcagtgac atcggtactt ataactatgt ctcctggtac caacagcatc
      181 caggcacagc ccccaaactc atgatttttg aggtcagtga gcggccctca ggggtctctg
      241 atcgcttctc tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg
      301 ctgaggacga ggctgattat tactgttgct catatgcaga cacctacact tttgtgtttg
      361 gaggtggcac cagattgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt
      421 tcccg
//
LOCUS       KCVO01000941             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:6393:3123
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000941
VERSION     KCVO01000941.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:6393:3123"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72970.1"
                     /translation="DYYCQVWDSSGDVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          141 c          140 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 ccattggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttgtactgg
      241 tcatctatgc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 attgtcaggt gtgggacagt agtggtgatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000942             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:13878:10776
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000942
VERSION     KCVO01000942.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13878:10776"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72971.1"
                     /translation="DYYCQVWDSGSDHWVF"
     J_segment       392..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           80 a          147 c          144 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca caggctctgc ggtctcttat gtcctgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggcccg gatcacctgt gggggagaca
      181 acattggagg taaaagtgtg cagtggttcc agcagaagcc accgcaggcc cctgtgctgg
      241 tcatttatgc tgatagcgaa cggccctcag ggatccctgc gcgattttct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cgggaatgag gctgactatt
      361 actgtcaggt gtgggacagt ggtagtgatc attgggtgtt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000943             534 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:5967:17467
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000943
VERSION     KCVO01000943.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 534)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:5967:17467"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    163..496
                     /note="immunoglobulin light chain variable region"
     V_region        163..496
     V_segment       163..456
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <418..>468
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72972.1"
                     /translation="DYYCQSYDSSLSAHVLF"
     J_segment       463..496
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        497..>534
                     /gene="IGLC"
BASE COUNT          104 a          166 c          145 g          119 t
ORIGIN      
        1 acatggggct cccactctca gagcatgaag aggggcaggg agagatttgg ggaagctctg
       61 cttcagctgt gggcacagga ggcagcactc aggacagtct ccagcatggc ctggtctcct
      121 ctcctcctca cccttctcat tcactgcaca gggtcctggg cccagtctgt gttgacgcag
      181 ccgccctcag tgtctggggc gcccgggcag agggtcacca tctcctgcac tgggagcagc
      241 tccaacattg gagattatta tgtgcagtgg taccagcagc ttccaggaac ggcccccaaa
      301 ctcctcatct atgaaaatga taagcgaccc tcagggattt ctgatcgatt ctctggctcc
      361 cagtctggtg cctcagcctc cctgaccatc actggactcc agtctgagga tgaggctgat
      421 tattactgcc agtcctatga cagcagcctg agtgctcatg tattattcgg aggagggacc
      481 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000944             573 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:19757:18087
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000944
VERSION     KCVO01000944.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 573)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 573)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..573
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19757:18087"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    211..532
                     /note="immunoglobulin light chain variable region"
     V_region        211..532
     V_segment       211..498
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <460..>507
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72973.1"
                     /translation="DYYCYSSDSTADYWVF"
     J_segment       499..532
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        533..>573
                     /gene="IGLC"
BASE COUNT          110 a          188 c          143 g          132 t
ORIGIN      
        1 acatggggga ttcctctcct actccccctc ctcactttct gcacaggtgc tgctcctagg
       61 ccctgaccca ggctcagtcc ccatagaccc caagttggcc ctgccctgaa ccctgtacta
      121 agcccagaca cagcctcagg gtgggacccc tgggaatggg ctcttcatct tcaagccccc
      181 tctcctgttt tccttgcagg ctctgcagcc tcctatgagc tgacacagcc accctcggtg
      241 tcagtgtccc cagtacagac ggccaggatc acctgctctg gagatgcatt gccagaaaaa
      301 tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgattat ttatgaggac
      361 agcaaacggc cctctgggat ccctgagaga ttctctggtt ccagctcagg gacagtggcc
      421 accttgacta tcagtggggc ccaggtgcag gatgaagctg actactactg ttactcatca
      481 gatagcactg ctgattattg ggtgttcggc ggagggaccc ggctgaccgt cccaggtcag
      541 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000945             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:26273:7085
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000945
VERSION     KCVO01000945.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:26273:7085"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72974.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          160 c          125 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagtcac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000946             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:19105:19385
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000946
VERSION     KCVO01000946.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:19105:19385"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72975.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           98 a          144 c          122 g           97 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc catcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcgtt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccagaaaa atatgcttat tggtaccagc agaaaccagg ccagtcccct atgctgatca
      241 tctatgagga caacaaacgg ccctctggga tccctgaaag attctctggc tccagctcag
      301 ggacagtggc caccttgact atcactgggg cccaggtgga ggatgaagct gactactact
      361 gttactcagc agacaacagt ggtcagggct cattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000947             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:24962:5339
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000947
VERSION     KCVO01000947.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:24962:5339"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72976.1"
                     /translation="DYYCQSGDSSTNHYIF"
     J_segment       392..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          105 a          138 c          120 g          103 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatgctc ggtggttcca gcagaagcca ggccaggccc ctgtcctggt
      241 gatatataaa gacactgaga ggccctcagg gatccctgag cgattctcta gttccagttc
      301 agggacaata cttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca ggagacagca gtactaatca ttacatcttc ggtgctggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCVO01000948             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:10047:8921
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000948
VERSION     KCVO01000948.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10047:8921"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..400
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72977.1"
                     /translation="NYYCSSYEGSNTFLF"
     J_segment       401..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           93 a          156 c          118 g          105 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcggcactc tcgggacatc tccaccatgg cctgggatct
       61 gctcctcttc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctca atgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaatcaa
      181 cagtgacatt ggtaattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcacg atttatgacg atagtcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaactcgg cctccctgac catctctggg ctccaggcag aggatgaggc
      361 taattattac tgcagctcat atgaaggcag caacactttc ttattcggag gagggacccg
      421 actgaccgtc ctgggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000949             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:11009:9042
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000949
VERSION     KCVO01000949.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11009:9042"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72978.1"
                     /translation="DYYCVIWHNNVWVF"
     J_segment       403..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          153 c          121 g          112 t
ORIGIN      
        1 acatggggac tgcggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaccctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgcgcagt ggcatcagtg
      181 ttggtagtta cagggtattc tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gataaccacc agggatctgg agtccccagc cggttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gtgatttggc acaacaatgt ttgggtattc ggcggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000950             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:7129:11038
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000950
VERSION     KCVO01000950.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:7129:11038"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72979.1"
                     /translation="DYYCGSYRRGSTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           83 a          151 c          133 g          108 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcgggac gtctccacca tggcttgggc
       61 tctggtcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtccgtc accatctcct gcactggaac
      181 caagagtgac attggtggtt ataacggtgt ctcctggtac caacagtatt caggcacagc
      241 ccccagactc ctgatttatg aggtcagtca gcggccctca ggggtctctg atcgcttctc
      301 tgggtacaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgcggct catataggag gggaagcact tgggtgttcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000951             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:14476:20642
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000951
VERSION     KCVO01000951.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:14476:20642"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..388
                     /gene="IGLV7-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72980.1"
                     /translation="EYYCWLHYSGVDVF"
     J_segment       390..427
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          147 c          119 g          110 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat accagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcactga ctgtgtcccc aggagggaca gtcactctca cttgtggctc cagtgctgga
      181 gcagtcactg ggagtcatta tccctactgg ttccagcaga agcctggcca agcccctaga
      241 acactgattt atgatacaga caacaaactc tcctggaccc ctgcccggtt ctcaggctcc
      301 ctccttgggg gtaaagctgc cctgacactg tcaggtgcgc agcctgagga tgaagctgag
      361 tattactgct ggctgcacta tagtggtgtt gatgtgttcg gaactggcac caagttgacc
      421 gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01000952             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:20124:2292
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000952
VERSION     KCVO01000952.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:20124:2292"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..392
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72981.1"
                     /translation="DYYCFVYYSGTQFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           99 a          152 c          115 g           99 t
ORIGIN      
        1 acatgggggg agccagagat cccttccaat accagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtggctc cagcactgga
      181 gcagtcacca gtggtaactt tccaaactgg ttccagcaga aacctggaca agtccccagg
      241 ggactgattt acaatacaaa caacaaacac tcctggaccc ctgcccggtt ctcaggctcc
      301 ctcgctgggg gcaaagctgt cctgacactg tcaggagcac agcccgagga cgaggctgat
      361 tattactgct tcgtgtacta tagtggtact caattcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000953             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:16934:2662
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000953
VERSION     KCVO01000953.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16934:2662"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..446
                     /note="immunoglobulin light chain variable region"
     V_region        117..446
     V_segment       117..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72982.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       411..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>485
                     /gene="IGLC"
BASE COUNT           90 a          156 c          127 g          112 t
ORIGIN      
        1 acatggggtc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatgtcct
      181 gcactgggag cagctccaac attggaggtt attatgtgca gtggtacctg caacttccag
      241 gaacggcccc caaacttctc atctatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggtacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cctgagtgcc gtgttattcg
      421 gaggagggac ccggctgacc gtcctaagtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01000954             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:16647:12863
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000954
VERSION     KCVO01000954.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16647:12863"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72983.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       413..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           91 a          158 c          129 g          109 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcaccatctc
      181 ctgcactggg agcagctcca acattggagg ttattatgtg cagtggtacc agcagcttcc
      241 aggaacggcc cccaaactcc tcatgtatga aaataataag cgaccctcag gggtttctga
      301 tcgattctct ggctcccagt ctggtacctc agcctccctg accatcactg gactccagtc
      361 tgaggatgag gctgattatt actgccagtc ctatgacagc agcctgagtg ccgtgttatt
      421 cggagcaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCVO01000955             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:14382:17872
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000955
VERSION     KCVO01000955.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14382:17872"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72984.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          146 c          126 g          101 t
ORIGIN      
        1 acaggggggc tgtgggctca ggaggcagag ctctgggtgt ctcaccatgg cctggattcc
       61 tctcctactc cccctcctca ctttctgcac aggctctgca gcctcctctg agctgacaca
      121 gccaccctcg gtgtcagtgt cccccggaca gacggccagg atcacctgct ctggaaatgc
      181 attgccaaaa tactatgctt attggttcca gcagaagcca ggccagtccc ctgtggcgat
      241 catctatgag gacaacaaac ggccctctgg gatccctgag agattctctg gctccagctc
      301 agggacagtg gccaccttga ctatcagtgg ggcccaggta gaggatgagg ctgactacta
      361 ctgttactca acagatagca gtggtactaa tggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000956             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:11929:12352
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000956
VERSION     KCVO01000956.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:11929:12352"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..431
                     /note="immunoglobulin light chain variable region"
     V_region        105..431
     V_segment       105..400
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72985.1"
                     /translation="DYFCSSYTGSITLF"
     J_segment       401..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>470
                     /gene="IGLC"
BASE COUNT           87 a          157 c          118 g          108 t
ORIGIN      
        1 acatgggggg gggtctcagg aggcagcgct ctcaggacgt ctccaccatg gtctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctccctc tgtgtctgga tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cggtggttat aactatgtct cctggtacca acggcaccca ggcaaagccc
      241 ccaaactcat gatttatgat gtcaataagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaaatc tggcaacacg gcctccctga ccatctctgg gctccagtct gaggatgagg
      361 ctgattattt ctgcagctca tatacaggca gcatcacttt attcggagga gggacccggc
      421 tgaccgtcct acgtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000957             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:21705:18083
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000957
VERSION     KCVO01000957.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21705:18083"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..448
                     /note="immunoglobulin light chain variable region"
     V_region        121..448
     V_segment       121..408
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72986.1"
                     /translation="DYYCYSTENSDTHRGFF"
     J_segment       412..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           96 a          149 c          134 g          107 t
ORIGIN      
        1 acatggggct agggagccca gctgtgctgt gggctcagga ggcagagctc tgggtgtctc
       61 accatggcct ggattcctct cctactcccc ctcctcactt tctgcacagg ctctgcagcc
      121 tcctatgagc tgacacagcc accctcggtg tcagtgtccc caggacagac ggccaggatc
      181 tcctgctctg gagatgcatt gccaaaaaaa tttgcttctt ggttccagca gaaggcaggc
      241 cagtcccctg tgctgatcat ctatgaggac agcaaacggc cctctgggat ccctgagaga
      301 ttctctggct ccagttcagg gacagtggcc accttgacta tcagtggggc ccaggtggag
      361 gatgaagctg actactactg ttactcaaca gagaacagtg atactcatag gggcttcttc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01000958             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:9210:13298
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000958
VERSION     KCVO01000958.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9210:13298"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..423
                     /note="immunoglobulin light chain variable region"
     V_region        101..423
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72987.1"
                     /translation="DYYCYSSDISGNHRVF"
     J_segment       390..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>463
                     /gene="IGLC"
BASE COUNT           94 a          139 c          124 g          106 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaagac agtaaacggc cctctgggat ccctgagaga ttctctggct ccacttcagg
      301 gacagtggcc accttgacta ttagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcatca gatatcagtg ggaatcatag ggtattcggc ggagggaccc ggctgaccgt
      421 ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000959             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:6814:10425
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000959
VERSION     KCVO01000959.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:6814:10425"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72988.1"
                     /translation="DYYCQVWDSSNDHILF"
     J_segment       395..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           91 a          145 c          135 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaga taaatatgta cactggtacc aacaaaagcc agcgcgggcc cctgtgctgg
      241 tcatctacta tgatagtgac cggccctcat ggatccctga gcgattctct gggtccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtaatgatc atatcttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000960             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:12018:9175
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000960
VERSION     KCVO01000960.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:12018:9175"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72989.1"
                     /translation="DYYCSSTDSRDNHRVF"
     J_segment       390..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           95 a          142 c          127 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc acgttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagcaggg ataatcatag ggtattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000961             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:10748:6522
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000961
VERSION     KCVO01000961.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:10748:6522"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72990.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       379..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           97 a          135 c          116 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 tatattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaggacaaca
      241 aacggccctc tgggattcct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aaggtgacta ctactgttac tcaagagata
      361 gtagtgaaaa tcaaagcgtc ttcggtgctg ggacccggct cagcgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01000962             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:18638:11556
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000962
VERSION     KCVO01000962.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18638:11556"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..439
                     /note="immunoglobulin light chain variable region"
     V_region        94..439
     V_segment       94..403
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72991.1"
                     /translation="DYYCVIWHNNVWVF"
     J_segment       404..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           90 a          154 c          121 g          112 t
ORIGIN      
        1 acatggggca ctgcggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcgcagcctg tgctgactca gccaccctcc
      121 ctctcagcat ctcctggagc atcagccaga ctcacctgca ccttgcgcag tggcatcagt
      181 gttggtagtt acagggtatt ctggtaccag cagaagccag ggagtcctcc ccggtatctt
      241 ctgaactacc acacagactc agataaccac cagggatctg gagtccccag ccggttctct
      301 ggatccaaag atgcttcggc caatgcaggg attttactca tctctgggct ccagtctgag
      361 gatgaggctg actattactg tgtgatttgg cacaacaatg tttgggtatt cggcggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000963             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:10724:13883
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000963
VERSION     KCVO01000963.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10724:13883"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..397
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72992.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       398..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           85 a          160 c          119 g          107 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcactct caggacgtct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 tctccctctg tgtctgggtc tcctggacag tcggtcacca tttcctgcac tggaaccagc
      181 agtgacattg gtggttataa ccgtgtctcc tggtaccaac agcacccagg caaagccccc
      241 aaactcatga tttatgacgt cagtgatcgg ccctcagggg tctctgatcg cttctctggt
      301 tccaagtctg gcaacacggc ctccctgatc atctctgggc tccaggctga ggacgaggct
      361 gattattact gcagctcata cgcaagcact accacttggc tattcggcgg agggacccgc
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000964             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:12990:7496
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000964
VERSION     KCVO01000964.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:12990:7496"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72993.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          160 c          125 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgttg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000965             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:19989:2651
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000965
VERSION     KCVO01000965.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:19989:2651"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..422
                     /note="immunoglobulin light chain variable region"
     V_region        104..422
     V_segment       104..385
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72994.1"
                     /translation="DYYCQSTDSSGYIF"
     J_segment       386..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT          103 a          135 c          118 g          104 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctacac aggctctgtg gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actgacaaaa aattatgctc agtggttcca gcagaagcca ggccaggccc ctgtgctgct
      241 gatatataaa gacagtgaga ggccctcagg gattcctgag cgattctcta gctccagttc
      301 agggacaaca gttaccttga ccatcagtcg ggcccaggta gaagatgagg ctgactatta
      361 ttgtcaatca acagacagca gtggttacat cttcggtgct gggacccggc tcaccgtcct
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01000966             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:8514:15593
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000966
VERSION     KCVO01000966.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:8514:15593"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..426
                     /note="immunoglobulin light chain variable region"
     V_region        97..426
     V_segment       97..389
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72995.1"
                     /translation="DYYCQSFDSSLSAVLF"
     J_segment       391..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>465
                     /gene="IGLC"
BASE COUNT           87 a          152 c          123 g          103 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac gcagccgccc
      121 tctctgtctg gggcgcccgg gcagagggtc accatctcct gcactgggag cagcgccaac
      181 attgggggtt attatgtgca gtggtaccag cagcttccag gaacggcccc caaactcctc
      241 atctatgaaa ataataagcg accctcaggg gtttctgatc gattctctgg ctcccagtct
      301 ggaacctcag cctccctgac catcactgga ctccagtctg aggatgaggg tgattattac
      361 tgccagtcct ttgacagcag cctgagtgcc gtgttattcg gaggagggac ccggctgacc
      421 gtcctaagtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000967             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:15550:20930
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000967
VERSION     KCVO01000967.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15550:20930"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72996.1"
                     /translation="DYYCQSYDTRLRAWVF"
     J_segment       408..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          155 c          126 g          109 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gtgtctgggg cgcccgggca gagggtcacc atctcctgca
      181 ctgggagcag ctccaacatt ggagattatt ttgtgcagtg gtatcaacag cttccaggaa
      241 cggcccccaa actcctcatc tatgaaaatg atagacgacc ctcaggaatt tctgatcgat
      301 tctctggctc ccagtctgga acctcagcct ccctgaccat cactggactc cagtctgagg
      361 atgaggctga ttattactgc cagtcctatg acaccagatt gagggcttgg gtattcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01000968             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:14389:14961
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000968
VERSION     KCVO01000968.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14389:14961"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72997.1"
                     /translation="DYSCQSADGNFNWVF"
     J_segment       398..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           90 a          155 c          123 g          104 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcgtctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt tcattcagcc
      121 ccattctgtg tcggggtctc cggggcagac ggtcaccatc tcctgcaccc gcagcagtgg
      181 cagcattgac actaaatatg tacagtggta ccaacagcgc ccgggcagag ccccaatcac
      241 agtgatttac aaagataaac aaagaccctc tggggtccct gatcgattct ctggctccat
      301 cgacagctcc tccaattctg cctccctcac catctctggg ctgaagtctg aggacgaggc
      361 tgactactcc tgtcagtctg ctgatggcaa cttcaattgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01000969             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:12476:15552
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000969
VERSION     KCVO01000969.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:12476:15552"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72998.1"
                     /translation="DYYCQVWDSSSAVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          141 c          137 g           99 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggataca
      181 tcattggaag taaaagtgtg cagtggtacc agcagaagcc accgcaggcc cttgtgctgg
      241 tcatctatgc tgataacaaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggatcac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgctg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01000970             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:18438:3685
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000970
VERSION     KCVO01000970.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18438:3685"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV72999.1"
                     /translation="DYYCQVWDSNNDHVFF"
     J_segment       399..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          146 c          135 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atcttggaga taaatatcta cactggtacc accagaagcc agcgcaggcc cctgtgctgg
      241 tcatctacta tgatagtgac cggccctcat ggatccctga gcgattctct gggtccaagt
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt aataatgatc atgtcttttt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000971             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:16258:4527
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000971
VERSION     KCVO01000971.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16258:4527"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..442
                     /note="immunoglobulin light chain variable region"
     V_region        113..442
     V_segment       113..405
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73000.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       407..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>481
                     /gene="IGLC"
BASE COUNT           91 a          154 c          128 g          108 t
ORIGIN      
        1 acatgggggg cttcagctgt gggcacagga ggcagcactc aggacagtct ccagcatggc
       61 ctggtctcct ctcctcctca cccttctcat tcactgcaca gggtcctggg cccagtctgt
      121 gctgacgcag ccgccctcag tgtctggggc gcccgggcag agggtcacca tctcctgcac
      181 tgggagcagc tccaacattg gaggttatta tgtgcagtgg taccagcaac ttccaggaac
      241 ggcccccaaa gttctcatct atgaaaataa taagcgaccc tcaggggttt ctgatcgatt
      301 ctctggctcc cagtctggta cctcagcctc cctgaccatc actggactcc agtctgagga
      361 tgaggctgat tattactgcc agtcctatga cagcagcctg agtgccgtgt tattcggagg
      421 agggacccgg ctgaccgtcc taagtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01000972             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:25602:5601
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000972
VERSION     KCVO01000972.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:25602:5601"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73001.1"
                     /translation="DYYCSSFASTSTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          159 c          121 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcaatgac attggtagtt ataaccgtgt ctcctggtac caacaacacc caggcaaagc
      241 ccccaaactc atgatttgtg acgtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct cattcgcaag cactagcact tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000973             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:18115:9720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000973
VERSION     KCVO01000973.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:18115:9720"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73002.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          144 c          124 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctctgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gtcaaaatac tatgcttatt ggttccagca gaagccaggc cagtcccctg tggcgatcat
      241 ctatgaggac aacaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtcgag gatgaagctg actactactg
      361 ttactcaaca gatagcagtg gtactaatgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000974             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:14197:7971
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000974
VERSION     KCVO01000974.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14197:7971"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73003.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           86 a          155 c          123 g          109 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acaacaccca ggcaaagccc
      241 ccaaactctt gatttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca gtagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01000975             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:14298:10266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000975
VERSION     KCVO01000975.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:14298:10266"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..392
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73004.1"
                     /translation="DYYCFVYYSGTQFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           99 a          154 c          115 g           97 t
ORIGIN      
        1 acatgggggg agccagagat cccttccaat accagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtggccc cagcactgga
      181 gcagtcacca gtggtaactt tccaaactgg ttccagcaga aacctggaca agtccccagg
      241 ggactgattt acaatacaaa caacaaacac tcctggaccc ctgcccggtt ctcaggctcc
      301 ctcgctgggg gcaaagctgc cctgacactg tcaggagcac agcccgagga cgaggctgat
      361 tattactgct tcgtgtacta tagtggtact caattcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000976             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:20120:19035
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000976
VERSION     KCVO01000976.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:20120:19035"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73005.1"
                     /translation="DYYCYSADSSGNGLF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          141 c          127 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccacaaaaa tatgcttatt ggtgccagca gaaaccaggc cagtcccctg tggtgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc gccttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagcagtg gtaatggctt attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01000977             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:21569:12127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000977
VERSION     KCVO01000977.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:21569:12127"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73006.1"
                     /translation="DYYCYSTRGSGYHGLF"
     J_segment       375..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           89 a          140 c          118 g          102 t
ORIGIN      
        1 gcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatctct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtgcaggatg aagctgacta ctactgttac tcaactcgtg
      361 gcagtggtta tcatggctta ttcggaggag ggacctggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000978             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:17986:10132
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000978
VERSION     KCVO01000978.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:17986:10132"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73007.1"
                     /translation="DYYCAAWDDSLNSPFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          155 c          115 g          104 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaac
      181 attggaagta attatgtaaa ctggtaccag caactcccag gaacggcccc caaactcctc
      241 atctatttta ctaatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtcg
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcggcat gggatgacag cctgaacagt cccttcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000979             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:7157:3127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000979
VERSION     KCVO01000979.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:7157:3127"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73008.1"
                     /translation="DYYCQVWDITTDHDVF"
     J_segment       389..425
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           97 a          140 c          125 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatgacct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ttctgcggcc tcctatgagc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacct
      181 tggaagtaaa aatatacact ggtaccagca aaagccaccg caggcccctg tactggtcat
      241 ctattatgat gtcgaacggc cctcagggat ccctgagcga ttctctggcg ccaaatcagg
      301 aaacaccgcc accctcatca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattacta ctgatcatga tgtattcgga agtggcacca agttgaccgt
      421 cctcggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01000980             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:20238:6266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000980
VERSION     KCVO01000980.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20238:6266"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73009.1"
                     /translation="DYYCSSYAGGNTIIF"
     J_segment       401..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          162 c          119 g          106 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcggcactc tcgggacatc tccaccatgg cctgggatct
       61 gctcctcttc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctca atgtctgggt ctcctggaca gtcggtcacc atcccctgca ctggaaccag
      181 cagtgacatt ggtgcttatg accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg actttcgagg tcagtcagcg tccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct gtcaacacgg cctccctgac catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcagctcat atgcaggcgg taacactata atcttcggtc ctgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01000981             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:10400:10143
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000981
VERSION     KCVO01000981.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10400:10143"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..425
                     /note="immunoglobulin light chain variable region"
     V_region        103..425
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73010.1"
                     /translation="DYYCQVWDFSGDHNIF"
     J_segment       392..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>465
                     /gene="IGLC"
BASE COUNT           89 a          148 c          130 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatgac ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctctga gctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagaa tcacctgtgg gagagacaac
      181 attggaaata agaatgtgca ctggtaccag cagcggccac cgcgggcccc tatactggtc
      241 atctattatg ataccgagcg gccctcaggg atccctgagc gattctctgg gtccacatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggactttag tggtgatcat aacatcttcg atgctgggac ccggctcacc
      421 gtcctcggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCVO01000982             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:18958:13991
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000982
VERSION     KCVO01000982.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18958:13991"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..437
                     /note="immunoglobulin light chain variable region"
     V_region        110..437
     V_segment       110..397
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73011.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       401..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           94 a          145 c          128 g          108 t
ORIGIN      
        1 acatggggag ctgtgctgtg ggctcaggag gcagagctct gggtgtctca ccatggcctg
       61 gattcctctc ctactccccc tcctcacttt ctgcacaggc tctgcagcct cctatgagct
      121 gacacagcca ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg
      181 agatgcattg ccaaaaaaat ttgcttcttg gttccagcag aagccaggcc agtcccctgt
      241 gttgatcatc tatgacgaca gcaaacggcc ctctgggatc cctgagagat tctctggctc
      301 cagctcaggg acagtggcca ccttgactat cattggggcc caggtggagg atgaagctga
      361 ctaccactgt ttctcaacag atagtagtgg taatcatagg ggcttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000983             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:11407:10558
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000983
VERSION     KCVO01000983.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11407:10558"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73012.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          143 c          138 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gaactcactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggaggca
      181 atgttggaag tgaatatgtc cactggtatc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatctatta taatactgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt aggagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000984             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:16029:8067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000984
VERSION     KCVO01000984.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16029:8067"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73013.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       413..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           90 a          157 c          130 g          110 t
ORIGIN      
        1 acatggggga gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcaccatctc
      181 ctgcactggg agcagttcca acattggagg ttattatgtg cagtggtacc agcagcttcc
      241 aggaacggcc cccaaactcc tcatgtatga aaataataag cgaccctcag gggtttctga
      301 tcgattctct ggctcccagt ctggtacctc agcctccctg accatcactg gactccagtc
      361 tgaggatgag gctgattatt actgccagtc ctatgacagc agcctgagtg ccgtgttatt
      421 cggagcaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCVO01000985             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:5576:14979
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000985
VERSION     KCVO01000985.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:5576:14979"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73014.1"
                     /translation="DYYCGSYSSGTTWKF"
     J_segment       406..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           82 a          158 c          128 g          107 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcgggac gtctccacca tggcttgggc
       61 tctggtcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtccgtc accatctcct gcactggaac
      181 cagcagtgac attggtggtt ataacggtgt ctcctggtac cagcagcact caggcacagc
      241 ccccagactc ctgatttatg aggtcagtca gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggctaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tactgcggct catatagcag tggaaccact tggaaattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000986             445 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:20573:19031
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000986
VERSION     KCVO01000986.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 445)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20573:19031"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..407
                     /note="immunoglobulin light chain variable region"
     V_region        86..407
     V_segment       86..367
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <335..>379
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73015.1"
                     /translation="DYYCQVWDSSSDVFF"
     J_segment       370..407
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        408..>445
                     /gene="IGLC"
BASE COUNT           87 a          128 c          131 g           99 t
ORIGIN      
        1 acatggggag atctcctcca gcagcagctc ctgactctgc tgatttgcat catgggctgt
       61 tctcttcagc aaagactctg tggtctccta tgaattgact cagccacgct cagtgtccgt
      121 gtccccagga cagacggcca ggatcacctg tgggggagac agcattggaa gtacaggtgt
      181 gcagtggtac cagcagaagc caccgctggc ccttgtactg gtcatctatg ctgatagcga
      241 acggccctca gggatccctg agcgattctc tggctgcaat ttagggaaca ccgccaccct
      301 gaccatcagc ggcgtcgagg ccggggatga ggctgactat tactgtcagg tgtgggacag
      361 tagtagtgat gtgttcttcg gaggagggac ccggctgacc gtcctaggtc agcccaaggc
      421 tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000987             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:4856:11705
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000987
VERSION     KCVO01000987.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:4856:11705"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..441
                     /note="immunoglobulin light chain variable region"
     V_region        120..441
     V_segment       120..407
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73016.1"
                     /translation="DYYCHSLDTSGNDVF"
     J_segment       411..441
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           94 a          148 c          132 g          105 t
ORIGIN      
        1 acatggggag gggagcccag ctgtgctgtg ggctcaggag gcagagctct gggtgtctca
       61 ccatggcctg gattcctctc ctactccccc tcctcacttt ctgcacaggc tctgcagcct
      121 cctatgagct gacacagcca ccctcggtgt cagtgtcccc aggacagacg gccaggatca
      181 cctgctctgg agatgcattg ccaaaaaaat ttgcttactg gttccagcag aagccaggcc
      241 agtcccctgt ggcgatcatc tatgaggaca ccaaacggcc ctctgggatc cctgagagat
      301 tctctggctc cagctcaggg acagtggcca ccttgactat cagtggggcc caggtggagg
      361 atgaagctga ctactactgt cattcattag ataccagtgg taatgatgtt ttcggcggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000988             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:13394:5124
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000988
VERSION     KCVO01000988.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:13394:5124"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73017.1"
                     /translation="DYYCQVWDSSSQYIF"
     J_segment       393..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          151 c          132 g           92 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgc ggcctcctat gacctgactc
      121 agccaccctc ggtgtcggtg tccccaggac agacagccag gatcacctgt gggggagaca
      181 acattggaag taaaagtgtg cactggtacc agcagaggcc accgcaggcc cctgtcctgg
      241 tcatatatac tgatagcgaa cggccctcag ggatccctga ccgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtcagt acatcttcgg tgctgggacc cggctcaccg
      421 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCVO01000989             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:25884:10066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000989
VERSION     KCVO01000989.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25884:10066"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..446
                     /note="immunoglobulin light chain variable region"
     V_region        101..446
     V_segment       101..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73018.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       410..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           89 a          161 c          126 g          108 t
ORIGIN      
        1 acatgggggg gggtctgtgg cctcagaggt agccgtgtcc accatggccc tgactcctct
       61 cctcctcctg ctcctctctc actgcacagg ttccctctcc cagcctgtgc tgactcagcc
      121 accctccctg tctgcatccc cgggagcatc ggccagactc ccctgcaccc tgagcagtga
      181 cctcagtgtt ggtagtaaaa acatatactg gtaccagcag aagccaggga gcgctcccag
      241 gttattcctg tactactact ccgactcaga caagcagctg ggacctgggg tccccaatcg
      301 agtctctggc tccaaggaga cctcaagtaa cacagcgttt ttgctcatct ctgggctcca
      361 gcctgaggac gaggccgatt attactgtca ggtgtatgac agtactggag tgttgttcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCVO01000990             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:19353:15746
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000990
VERSION     KCVO01000990.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19353:15746"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..381
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73019.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       384..421
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           86 a          141 c          137 g           95 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctgcacagac tctgtggtct cctatgaatt gactcagcca
      121 cgctcagtgt ccgtgtcccc aggacagacg gccaggatca cctgtggggg agacagcatt
      181 ggaagtagaa gtgtgcagtg gtaccagcag aagccaccgc aggcccttct actggtcatc
      241 tatgctgata ccgaacggcc ctcagggatc cctgagcgat tctctggctc caatttaggg
      301 aacaccgcca ccctgaccat cagcggcgtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtagtag tgatgtgtta ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01000991             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:12697:16791
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000991
VERSION     KCVO01000991.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:12697:16791"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..309
                     /note="immunoglobulin light chain variable region"
     V_region        87..309
     V_segment       87..269
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>281
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73020.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       273..309
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        310..>347
                     /gene="IGLC"
BASE COUNT           69 a          106 c           96 g           76 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagc agaaggcagg ccagtcccct gtgctgatca
      121 tctatgagga cagcaaacgg ccctctggga tccctgagag attctctggc tccagttcag
      181 ggacaatggc caccttgact atcagtgggg cccaggtgga ggatgaagct gactactact
      241 gttactcaac agataacagt gatactcata ggggcttctt cggaggaggg acccggctga
      301 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01000992             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:16239:14413
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000992
VERSION     KCVO01000992.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16239:14413"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73021.1"
                     /translation="DYYCQVWDSSRDHPIF"
     J_segment       392..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           80 a          145 c          136 g          103 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag tctctgcggt ctcctatgag ttgactcagc
      121 caccctcggt gtcagtgtcc ccaggacgga cggccaggat cacgtgtggg ggagacatcg
      181 ttggaagtga atatgttcac tggtatcagc agaagtcagc gcaggcccct gtggtggtca
      241 tctattatta ttctgaccgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggagcaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactactact
      361 gtcaggtgtg ggacagtagt cgtgatcatc ccatcttcgg tgctgggacc cgactcaccg
      421 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCVO01000993             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:11076:17959
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000993
VERSION     KCVO01000993.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:11076:17959"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73022.1"
                     /translation="DYYCQVWDSSSKYMIF"
     J_segment       395..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          151 c          133 g           89 t
ORIGIN      
        1 acatggggct gggtctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcga cctcctatga gctgactcag
      121 ccaccctcgg tgtcagcggc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagtt acaatgtgca ctggtaccag cagaagccac cccaggcccc tgtgctggtc
      241 atctatgctg atagcaagcg gccctctggc atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcagg gtcgaggccg gggatgaggc tgactactac
      361 tgtcaggtgt gggacagtag tagtaaatac atgatattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01000994             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:18709:16680
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000994
VERSION     KCVO01000994.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18709:16680"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73023.1"
                     /translation="DYYCYSTDNSGTHRGFF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           95 a          142 c          127 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaagcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaaggcaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagttcagg
      301 gacagtggcc aacttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gataacagtg gtactcatag gggcttcttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000995             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:10236:14175
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000995
VERSION     KCVO01000995.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10236:14175"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    125..455
                     /note="immunoglobulin light chain variable region"
     V_region        125..455
     V_segment       125..419
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <383..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73024.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       420..455
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           87 a          167 c          122 g          117 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac agtgtgtttc tccctctttc caggatcctg
      121 ggctcaggct gccctgactc agtctccctc tgtgtctggg tctcctggac agtcggtcac
      181 catttcctgc actggaacca gcagtgacat tggtggttat aaccgtgtct cctggtacca
      241 acagcaccca ggcaaagccc ccaaactcat gatttatgac gtcagtgatc ggccctcagg
      301 ggtctctgat cgcttctctg gttccaagtc tggcaacacg gcctccctga tcatctctgg
      361 gctccaggct gaggacgagg ctgattatta ctgcagctca tacacaagca ctaccacttg
      421 gctattcggc ggagggaccc gcctgaccgt cctaggtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCVO01000996             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:17846:14433
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000996
VERSION     KCVO01000996.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17846:14433"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..397
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73025.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       398..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           83 a          162 c          118 g          108 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcactct caggacgtct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 tctccctctg tgtctgggtc tcctggacag tcggtcaccc tttcctgcac tggaaccagc
      181 agtgacattg gtggttataa ccgtgtctcc tggtaccaac accacccagg caaagccccc
      241 aaactcatga tttatgacgt cagtgatcgg ccctcagggg tctctgatcg cttctctggt
      301 tccaagtctg gcaacacggc ctccctgatc atctctgggc tccaggctga ggacgaggct
      361 gattattact gcagctcata cgcaagcact tccacttggc tattcggcgg agggacccgc
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01000997             320 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1101:18419:8250
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000997
VERSION     KCVO01000997.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 320)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:18419:8250"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..282
                     /note="immunoglobulin light chain variable region"
     V_region        8..282
     V_segment       8..245
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <207..>254
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73026.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       250..282
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        283..>320
                     /gene="IGLC"
BASE COUNT           69 a           86 c          100 g           65 t
ORIGIN      
        1 acatgggggc caggatcacc tgtgggggag acaatgttgg aagtgaatat gtgcactggt
       61 accaacagaa accagcgcag gcccctgtgg tggtcatcca ttataatagt gaccggccct
      121 cagggatccc tgagcgattc tctggctcca aatcagggaa caccgccacc ctgaccatca
      181 gcggggtcga ggccggggat gaggctgact attactgtca ggtgtgggac agtagtagtg
      241 atcattgtgt attgggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc
      301 cctcggtcac tctcttcccg
//
LOCUS       KCVO01000998             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:6698:9304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000998
VERSION     KCVO01000998.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:6698:9304"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..436
                     /note="immunoglobulin light chain variable region"
     V_region        108..436
     V_segment       108..402
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73027.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       403..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>476
                     /gene="IGLC"
BASE COUNT           85 a          156 c          125 g          110 t
ORIGIN      
        1 acatgggggg ctgggatctc aggaggcagc actctcagga cgtctccacc atggcctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccctga
      121 ctcagtctcc ctctgtgtct gggtctcctg gacagtcggt caccatttcc tgcactggaa
      181 ccagcagtga cattggtgat tataaccgtg tctcctggta ccaacagcac ccaggcaaag
      241 cccccaaact catgatttat gaggtcagtg atcggccctc aggggtctct gatcgcttct
      301 ctggttccaa gtctggcaac acggcctccc tgatcatctc tgggctccag gctgaggacg
      361 aggctgatta ttactgcagc tcatacacta gcagtagcac ttgggtattc ggcggaggga
      421 cccggctgac cgtccttggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01000999             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:24563:7222
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01000999
VERSION     KCVO01000999.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:24563:7222"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73028.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       387..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           93 a          142 c          124 g           99 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 cagaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgtg ttgatcatca
      241 atgaggacag caaacggccc tctgggatcc ctgagagaat ctctggctcc agctcaggga
      301 cagtggccac cttgactctc agtggggccc aggtggagga tgaagctgac tactactgtt
      361 cctcaacaga tagtagtggt aatcatgtat tcggcggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001000             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:11442:14542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001000
VERSION     KCVO01001000.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:11442:14542"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73029.1"
                     /translation="DYYCYSSDSSADYWVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>449
                     /gene="IGLC"
BASE COUNT           87 a          139 c          119 g          104 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcccct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtctt gattatttat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggttccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcatcagata
      361 gcagtgctga ttattgggtg ttcggcggag ggacccggct gaccgtccca ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001001             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:22552:3600
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001001
VERSION     KCVO01001001.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22552:3600"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73030.1"
                     /translation="DYYCFSSDSSADYWVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           89 a          142 c          127 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac accaaacggc cctctgggat ccctgagaga ttctctggtt ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 tttctcatca gatagcagtg ctgattattg ggtgttcggc ggagggaccc ggctgaccgt
      421 cccaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001002             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:17825:10342
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001002
VERSION     KCVO01001002.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:17825:10342"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..436
                     /note="immunoglobulin light chain variable region"
     V_region        115..436
     V_segment       115..399
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73031.1"
                     /translation="DYYCYSTDSSGNGLF"
     J_segment       400..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           97 a          147 c          127 g          103 t
ORIGIN      
        1 acatggggag cccagctgtg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg
       61 gcctggattc ctctcctact ccccatcctc actttctgca caggctctgc agcctcctat
      121 gagctgacac agccaccctc gttgtcagtg tccccaggac agacggccag gatcacctgc
      181 tctggagatg cattcccaga aaaatttgct tattggtacc agcagaaacc aggccagtcc
      241 cctgtgctga tcatctatga ggacagcaaa cggccctctg ggatccctga gagattctct
      301 ggctccagct cagggacagt ggccaccttg actatcagtg gggcccaggt ggaggatgaa
      361 gctgactact actgttactc aacagacagc agtggtaatg gcttattcgg aggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001003             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:20695:2246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001003
VERSION     KCVO01001003.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20695:2246"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73032.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       400..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          148 c          134 g           97 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acaggctctg cggtctccta tgagctgact
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 aaccttggag ataagtatct acactggtac caccagaagc caacgcaggc ccctgtcctg
      241 gtcatctact atgatagtga ccggccctca tggatccctg agcgattctc tgggtccaag
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag taataatgat catatctttt tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001004             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:16120:6243
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001004
VERSION     KCVO01001004.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16120:6243"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..430
                     /note="immunoglobulin light chain variable region"
     V_region        104..430
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73033.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       399..430
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>472
                     /gene="IGLC"
BASE COUNT           86 a          155 c          122 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggttattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat atgcaagcac tagcacttgg ctattcggcg gagggacccg
      421 gctgaccgtc gtaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001005             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:4680:6227
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001005
VERSION     KCVO01001005.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:4680:6227"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73034.1"
                     /translation="DYYCAAWDDSLSSPLF"
     J_segment       393..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          153 c          116 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaac
      181 attggaagta attatgtaaa ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 atctatttta gtaatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcat gggatgacag cctgagcagt cccttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001006             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:20788:21341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001006
VERSION     KCVO01001006.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20788:21341"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73035.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           84 a          160 c          119 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctctggt gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001007             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:2686:12731
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001007
VERSION     KCVO01001007.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:2686:12731"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73036.1"
                     /translation="DYYCYSTDNSGNHIF"
     J_segment       388..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           94 a          146 c          119 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaggctg actactactg
      361 ttactcaaca gataacagtg gtaatcacat cttcgctgct gggacccggc tcaccgtcct
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01001008             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:13591:16441
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001008
VERSION     KCVO01001008.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13591:16441"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..455
                     /note="immunoglobulin light chain variable region"
     V_region        122..455
     V_segment       122..415
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73037.1"
                     /translation="DYYCLSYDTSLSAHYIF"
     J_segment       418..455
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           97 a          166 c          122 g          108 t
ORIGIN      
        1 acatgggggg gaagctctgc ttcagctgtg ggcacaggag gcagcactca ggacagtctc
       61 cagcatggcc tcgtctcctc tcctcctcac ccttctcatt cactgcacag ggtcgtgggc
      121 ccagtctgtg ctgacacagc caccctcagt gtctggggcc ccagggcaga gggtcaccat
      181 ctcgtgcact gggagcagct ccagcattgg aggtgattat gtatcctggt accaacacct
      241 cccaggaacg acccccaaac tcctcatcta tcaaaagaat aagcgaccct caggggtttc
      301 tgaccgatac tctggctcca agtctggtac ctcagcctcc ctgaccatca ctgggctcca
      361 gactgaggat gaggctgatt actactgtct gtcctatgac accagcctga gtgctcatta
      421 catcttcggt cctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt
      481 cactctgttc ccg
//
LOCUS       KCVO01001009             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:18060:6701
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001009
VERSION     KCVO01001009.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:18060:6701"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73038.1"
                     /translation="DYYCCSYSDIHTFVF"
     J_segment       407..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           83 a          158 c          119 g          115 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatcacct gtactggaac
      181 cagcagtgac atcggtgatt ataactttgt ctcctggtac caacaacatc caggcatagc
      241 ccccgaactc atgatttatg aggtcactaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcacct cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgctgct catattcaga catccacact tttgtattcg gaggtggcac
      421 caggttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001010             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:6873:12012
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001010
VERSION     KCVO01001010.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:6873:12012"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..395
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73039.1"
                     /translation="DYYCFVYYSGTQFF"
     J_segment       400..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT          100 a          153 c          115 g          100 t
ORIGIN      
        1 acatggggtc tggagccaga gatcccttcc aataccagca ccatggcctg gactctgctc
       61 ctcctccagt tcctcctcac ttgctgccca gggtccaatt cccaggctgt agtgactcag
      121 gagccctcaa tgaatgtgtc cccaggaggg acagtcactc tcacctgtgg ctccagcact
      181 ggagcagtca ccagtggtaa ctttccaaac tggttccagc agaaacctgg acaagtcccc
      241 aggggactga tttacaatac aaacaacaaa cactcctgga cccctgcccg gttctcaggc
      301 tccctcgctg ggggcaaagc tgccctgaca ctgtcaggag cacagcccga ggacgaggct
      361 gattattact gcttcgtgta ctatagtggt actcaatttt tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001011             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:9703:8092
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001011
VERSION     KCVO01001011.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:9703:8092"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..400
                     /gene="IGLV2-18"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73040.1"
                     /translation="DYYCSSYTGGNTFLF"
     J_segment       401..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          154 c          119 g          112 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcaggacttc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac agcatactgg gctcaggctg ccccggctca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgatttt ggttattata atgctgtgtc ttggtaccaa cagcatccag gcaaagcccc
      241 caaactcatg atttatgaag tcactaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aagatgaggc
      361 tgattattac tgcagctcat atacaggcgg caacactttc ttatttggag gggggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001012             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:7380:14747
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001012
VERSION     KCVO01001012.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:7380:14747"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73041.1"
                     /translation="DYYCSSYISSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           88 a          153 c          120 g          111 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg cctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtaatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aagacgaggc
      361 tgattattac tgcagctcat atataagtag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001013             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:13209:15720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001013
VERSION     KCVO01001013.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13209:15720"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73042.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          160 c          125 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggatga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001014             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:11751:15979
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001014
VERSION     KCVO01001014.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11751:15979"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..397
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73043.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       398..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           85 a          156 c          122 g          108 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcactct caggacgtct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 tctccctctg tgtctgggtc tcctggacag tcggtcacca tttcctgcac tggaaccagc
      181 agtgacattg gtggttataa ccgtgtctcc tggtaccaac agcacccagg caaagccccc
      241 aaactcatga tttatgaggt cagtgatcgg ccctcagggg tctctgatcg cttctctggt
      301 tccaagtctg gcaacacggc ctccctgatc atctctgggc tccaggctga ggacgaggct
      361 gattattact gcagctcata cgcaagcact agtacttggc tattcggcgg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001015             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:13672:18686
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001015
VERSION     KCVO01001015.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:13672:18686"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73044.1"
                     /translation="DYYCYSTRSSGYHGLF"
     J_segment       375..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           91 a          139 c          115 g          104 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctatgtt gatcatctat gaggacagca
      241 aacggccctc tgggatctct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtgcaggatg aagctgacta ctactgttac tcaactcgta
      361 gcagtggtta tcatggctta ttcggaggag ggacctggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001016             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:3789:15046
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001016
VERSION     KCVO01001016.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:3789:15046"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73045.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          142 c          138 g           99 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gtcgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctcactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggaggca
      181 atgttggaag tgaatatgtc cactggtatc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatctatta taatactgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt ttgggacagt aggagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001017             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:24532:12663
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001017
VERSION     KCVO01001017.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:24532:12663"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73046.1"
                     /translation="DYYCQVWDITTDHDVF"
     J_segment       390..426
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           95 a          138 c          130 g          101 t
ORIGIN      
        1 acatgggggg ggcctcagga ggcagcattg acggtgcctc agccatgacc tggacttttc
       61 tcctcctcgg cctccttgct tactgcacag gttctgcggc ctcctatgag ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaaca
      181 ttggaagtaa aaatgtacac tggtaccagc aaaagccacc gcaggcccct gtactggtca
      241 tctattatga tgtcgaacgg ccctcaggga tccctgagcg attctctggc gccaaatcag
      301 ggaacaccgc caccctgatc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacattact actgatcatg atgtgttcgg aagtggcacc aagttgaccg
      421 tcctcggtca gcccaaggct tcccccttgg tcactctgtt cccg
//
LOCUS       KCVO01001018             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:25540:18875
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001018
VERSION     KCVO01001018.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:25540:18875"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..427
                     /note="immunoglobulin light chain variable region"
     V_region        105..427
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73047.1"
                     /translation="DYYCQVWDSSSDHWVF"
     J_segment       392..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>467
                     /gene="IGLC"
BASE COUNT           86 a          143 c          141 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgc ggtctcctat gagctgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggcccg gatcacctgt gggggagaca
      181 acattggaag taaaagtgtg cagtggttcc agcaaaagcc accgcaggcc cctgtgttgg
      241 tcatttatgg tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccaact
      301 cagggaacat tgccaccctg accatcagcg gggtcgaggc cgggaatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgggtatt cggcggaggg acccggctga
      421 ccgtcctcgg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001019             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:3579:17753
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001019
VERSION     KCVO01001019.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:3579:17753"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..454
                     /note="immunoglobulin light chain variable region"
     V_region        130..454
     V_segment       130..417
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73048.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       418..454
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT          101 a          152 c          134 g          105 t
ORIGIN      
        1 acatggggaa gagaagccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactccccc tcctcacttt ctgcacaggc
      121 tctgcagcct cctctgagct gacacagcca ccctcggtgt cagtgtcccc aggacagacg
      181 gccaggatca cctgctctgg agatgcattg ccaaaatact atgcttattg gttccagcag
      241 aagccaggcc agtcccctgt ggcgatcatc tatgaggaca acaaacggcc ctctgggatc
      301 cctgagagat tctctggctc cagctcaggg acagtggcca ccttgactat cagtggggcc
      361 caggtcgagg atgaagctga ctactactgt tactcaacag atagcagtgg tactaatggc
      421 ttattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      481 actctcttcc cg
//
LOCUS       KCVO01001020             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:15413:19343
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001020
VERSION     KCVO01001020.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15413:19343"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73049.1"
                     /translation="DYYCYSMDSSTYLGFF"
     J_segment       387..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          144 c          122 g          103 t
ORIGIN      
        1 acatgggggg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactccccc tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agatgcattg
      181 ccaaaaaaat acgcttattg gttccagcag aagccaggcc agtcccctgt attgatcatc
      241 tatgaggaca ccaaacggcc ctctgggatc cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cagtggggcc caggtggagg atgaagctga ctactactgt
      361 tactcaatgg atagcagtac ttatcttggc ttcttcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001021             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:4274:5227
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001021
VERSION     KCVO01001021.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4274:5227"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73050.1"
                     /translation="DYYCQVWDSSSDHYIF"
     J_segment       393..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          141 c          140 g           98 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcacttta caggctctgc ggcctcctat gagctgactc
      121 agccacgctc ggtgtcggtg tcccagggac agacggccag gatcacctgt gggggagaca
      181 acattggaag tgaagctgtg cagtggtacc agcagaagcc agcgcaggcc cctgtgctgg
      241 tcatctatga tgatagcgaa cggccctcag ggatccctga tcgattctct ggctccaaat
      301 cagggaacac cgccaccatg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggatagt agtagtgatc attacatctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01001022             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:8459:10920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001022
VERSION     KCVO01001022.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:8459:10920"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73051.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       413..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          158 c          130 g          108 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggaccccg ggcagagggt caccatctcg
      181 tgcactggga gcagctccaa cattggaggt tattttgtgt actggtacca gcagttccca
      241 cgaacagccc ccaaactcct catctatgac aataataagc gaccctcagg gatttctgac
      301 cgattctctg gctccaagtc tggtacctca gcctccctga ccatcactgg gctccagcct
      361 ggggatgagg ctgattatta ctgcggagca tgggatagca gcctgagtgc tcgcttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01001023             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:12930:20597
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001023
VERSION     KCVO01001023.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:12930:20597"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..446
                     /note="immunoglobulin light chain variable region"
     V_region        117..446
     V_segment       117..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73052.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       411..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>485
                     /gene="IGLC"
BASE COUNT           91 a          156 c          128 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaggtt attatgtgca gtggtaccag caacttccag
      241 gaacggcccc caaagttctc atctatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggtacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cctgagtgcc gtgttattcg
      421 gaggagggac ccggctgacc gtcctaagtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001024             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:10617:14467
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001024
VERSION     KCVO01001024.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10617:14467"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..437
                     /note="immunoglobulin light chain variable region"
     V_region        93..437
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73053.1"
                     /translation="DYYSMIWHNNVWVF"
     J_segment       403..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>476
                     /gene="IGLC"
BASE COUNT           94 a          155 c          115 g          112 t
ORIGIN      
        1 acatggggac tgcggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaccctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgcgcagt ggcatcagtg
      181 ttggtagtta caggatattc tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gataaacacc agggatctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctgggctc cagtctgacg
      361 atgaggctga ctattactct atgatttggc acaacaatgt ttgggtattc ggcggaggga
      421 cccggctgac cgtcctaagt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001025             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:9266:17860
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001025
VERSION     KCVO01001025.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:9266:17860"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73054.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       387..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           91 a          142 c          124 g          101 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 cagaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgta ctgatcatca
      241 atgaggacag caaacggccc tctgggatcc ctgggagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactctc agtggggccc tggtggagga tgaagctgac tactactgtt
      361 cctcaacaga tagtagtggt aattatgtat tcggcggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001026             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:22541:16750
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001026
VERSION     KCVO01001026.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:22541:16750"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..368
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73055.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           94 a          142 c          115 g           95 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggta ccagcagaaa ccaggccagt cccctatgct gatcatctgt gaggacagca
      241 aacggccctc tgggatccct gaaagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcac tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 acagtggtca gggctcattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001027             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:8506:10229
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001027
VERSION     KCVO01001027.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:8506:10229"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73056.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           94 a          143 c          124 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctacccccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgagaga atctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtagag gatgaagctg actactactg
      361 ttcctcaaca gatagtagtg gtaatcatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001028             453 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:20779:16023
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001028
VERSION     KCVO01001028.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 453)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 453)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..453
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20779:16023"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..415
                     /note="immunoglobulin light chain variable region"
     V_region        85..415
     V_segment       85..377
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <340..>387
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73057.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       379..415
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        416..>453
                     /gene="IGLC"
BASE COUNT           84 a          148 c          117 g          104 t
ORIGIN      
        1 acatggggac tcaggacagt ctccagcatg gcctggtctc ctctcctcct cacccttctc
       61 attcactgca cagggtcctg ggcccagtct gtgctgacgc agccgccctc agtgtctggg
      121 gcgcccgggc agagggtcac catctcctgc actgggagca gttccaacat tggaggttat
      181 tatgtgcagt ggtaccagca gcttccagga acggccccca aactcctcat gtatgaaaat
      241 aataagcgac cctcaggggt ttctgatcga ttctctggct cccagtctgg tacctcagcc
      301 tccctgacca tcactggact ccagtctgag gatgaggctg attattactg ccagtcctat
      361 gacagcagcc tgagtgccgt gttattcgga gcagggaccc ggctgaccgt cctaggtcag
      421 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001029             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:15945:7157
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001029
VERSION     KCVO01001029.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15945:7157"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73058.1"
                     /translation="DYYCCSYEDTYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          155 c          117 g          112 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcagactg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtgcttata actatgtctc ctggtaccaa caacatccag gcacagcccc
      241 caaaatcatc atttatgagg tcagtaagcg gccctcaggg gtctctaatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgttgttcgt atgaagacac ctacactttt gtgttcggaa gtggcaccag
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01001030             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:20049:3902
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001030
VERSION     KCVO01001030.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20049:3902"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..412
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73059.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       414..449
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           91 a          157 c          131 g          108 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggacccc gggcagaggg tcaccatctc
      181 gtgcactggg agcagctcca acattggagg ttattttgtg tactggtacc agcagttccc
      241 aggaacagcc cccaaactcc tcatctatga caataataag cgaccctcag ggatttctga
      301 ccgattctct ggctccaagt ctggtacctc agcctccctg accatcactg ggctccagcc
      361 tggggatgag gctgattatt actgcggagc atgggatagc agcctgagtg ctcgcttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCVO01001031             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:8341:8903
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001031
VERSION     KCVO01001031.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8341:8903"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..414
                     /note="immunoglobulin light chain variable region"
     V_region        86..414
     V_segment       86..382
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73060.1"
                     /translation="NYYCGSYAGSDTFLF"
     J_segment       383..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>454
                     /gene="IGLC"
BASE COUNT           83 a          153 c          113 g          105 t
ORIGIN      
        1 acatggggac tctcgggaca tctccaccat ggcctgggat ctgctcctct tcaccctcct
       61 cactcagggc acaggatcct gggctcaggc tgccctgact cagcctccct caatgtctgg
      121 gtctcctgga cagtcggtca ccatctcctg cactggaatc agcagtgaca ttggtgatta
      181 taaccgtgtc tcctggtacc aacagcaccc aggcaaagcc cccaaactca cgatttatga
      241 cgatagtcag cggccctcag gggtctctga tcgcttctct ggctccaagt ctggcaactc
      301 ggcctccctg accatctctg ggctccaggc tgaggatgag gctaattatt actgcggctc
      361 atatgcaggc agcgacactt tcttattcgg aggtgggacc cggctgaccg tcctgggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001032             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:5714:7871
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001032
VERSION     KCVO01001032.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:5714:7871"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73061.1"
                     /translation="DYYCQVWDSSTDHTLL"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          143 c          137 g           96 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgag ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaatg
      181 ttggaagtga atatgtgcac tggtaccaac agaagccacc gcaggcccct gtggtggtca
      241 tccattataa tagtgaccgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt actgatcata ctttattggg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001033             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:15191:5447
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001033
VERSION     KCVO01001033.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15191:5447"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73062.1"
                     /translation="DYYCQVWDSITDHSIF"
     J_segment       394..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          148 c          133 g           99 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg cttactgcac agtctctgcg gtctcctatg agctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggggacaa
      181 cattggaact gaatatgtgc actggtacca gcagaagcca ccgcaggccc ctgtggtggt
      241 catctattat aatactgacc ggccctcagg gatccctgag cgattctcag gctccaaatc
      301 agggaacacc ggcaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta ttactgatca ttccatcttc ggtgttggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCVO01001034             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:17831:15892
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001034
VERSION     KCVO01001034.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17831:15892"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73063.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           83 a          153 c          125 g          114 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtggtt ttgagcgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc ttgatttatg aggtcagtta tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctgccaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tattgcagct catacacaag tagtagtact tgggtattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001035             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:10545:19618
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001035
VERSION     KCVO01001035.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10545:19618"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73064.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       394..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          141 c          138 g           96 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag actctgcggt ctcctatgac ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaatg
      181 ttggaagtga atatgtgcac tggtaccaac agaaaccagc gcaggcccct gtggtggtca
      241 tccattataa tagtgaccgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatcatt gtgtattggg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001036             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:13617:19804
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001036
VERSION     KCVO01001036.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13617:19804"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73065.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>470
                     /gene="IGLC"
BASE COUNT           82 a          156 c          119 g          113 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtactt ataactatgt ctcctggtac caacagcatc caggcacagc
      241 ccccaaactc atgatttttg aggtcagtga gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgttgct catatgcaga cacctacact tttgtgtttg gaggtggcac
      421 cagattgacc gtcctcgccc aaggcttccc ccttggtcac tctgttcccg
//
LOCUS       KCVO01001037             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:12178:5151
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001037
VERSION     KCVO01001037.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:12178:5151"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..427
                     /note="immunoglobulin light chain variable region"
     V_region        104..427
     V_segment       104..397
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73066.1"
                     /translation="DYFCCSYADTYTVVF"
     J_segment       404..427
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>472
                     /gene="IGLC"
BASE COUNT           83 a          156 c          122 g          111 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actttgtctc ctggtaccaa caacatccag gcacagcccc
      241 caaactcatg atttatgagg tcaatcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctcaaagtct ggcaacacgg cctccctgac cgtctccggg gtccaggctg aggacgaggc
      361 tgattatttc tgctgctcat atgcagacac ctacactgtt gttttcggaa gtggcaccag
      421 gttgaccgtc gtcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01001038             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:15007:20345
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001038
VERSION     KCVO01001038.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15007:20345"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73067.1"
                     /translation="DYYCSSYASSSTWIF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          155 c          122 g          106 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcata atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ctcaaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcag tagcacttgg atattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001039             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:15168:14614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001039
VERSION     KCVO01001039.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15168:14614"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73068.1"
                     /translation="DYYCQVWDSSSDHCLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          144 c          139 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc actgtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001040             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:16879:14810
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001040
VERSION     KCVO01001040.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16879:14810"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..431
                     /note="immunoglobulin light chain variable region"
     V_region        104..431
     V_segment       104..396
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73069.1"
                     /translation="DYYCLLYSSGVHLF"
     J_segment       398..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           96 a          157 c          113 g          103 t
ORIGIN      
        1 acatggggct ctggagccag agatcccttc caataccagc accatggcct ggactctgct
       61 cctcctccag ttcctcctca cttgctgccc agggtccaat tctcaggctg tagtgactca
      121 ggagccctca atgactgtgt ccccaggagg gacagtcact ctcacctgtg gctccagcac
      181 tggagcagtc accagtagta actttccaaa ctggttccag cagaaacctg gacaagtccc
      241 caggggactc atttacaata cacacaacaa acactcctgg acccctgccc ggttctcagg
      301 ctccctcgct ggggccaaag ctgccctgac actgtcaggt gcacagcccg aggacgaggc
      361 tgactattac tgcttgctgt attctagtgg tgttcattta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001041             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:12293:9192
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001041
VERSION     KCVO01001041.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:12293:9192"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73070.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       385..422
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           86 a          135 c          140 g           99 t
ORIGIN      
        1 acatggggtg gcctcgggaa gcagccttgg cggtgcctca gccatggccg ggacccttct
       61 cctcctcggc ctccttgctc actgcacaga ctctgtggtc tcctatgaat tgactcagcc
      121 acgctcagtg tccgtgtccc caggacagac ggccaggatc acctgtgggg gagacagtat
      181 tggaagtaga agtgtgcagt ggtaccagca gaagccaccg caggcccttg tgctggtcat
      241 gtatggtgat agtgaacggc cctcagggat ccctgatcga ttctctggct ccaatttagg
      301 gaacaccgcc accctgacca tcagcggcgt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtgatgtgtt attcggaaga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001042             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:16391:4700
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001042
VERSION     KCVO01001042.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16391:4700"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..412
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73071.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       414..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           92 a          156 c          130 g          110 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct
      181 cctgcactgg gagcagctcc aacattggag attattatgt gcagtggtac caacagcttc
      241 cagggacggc ccccaaattt ctcatctatg aaaatgataa gcgaccctca ggggtttctg
      301 atcgattctc tggctcccag tctggaacct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagcctgagt gccgtgttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCVO01001043             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:21644:9792
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001043
VERSION     KCVO01001043.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21644:9792"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73072.1"
                     /translation="DYYCCSYVGRFTFVF"
     J_segment       404..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          155 c          123 g          112 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctgggaccag
      181 cagtgacatc ggtggttatg actttgtctc ctggtaccaa cagcatccag gcacagcccc
      241 caaactcatg atttatgagg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagacc ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgacgc
      361 tgattattac tgctgctcat atgtaggcag gttcactttt gtattcggaa gtggcaccaa
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01001044             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:14144:11268
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001044
VERSION     KCVO01001044.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14144:11268"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73073.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           91 a          141 c          117 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gacgacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcat tggggcccag gtggaggatg aagctgacta ccactgtttc tcaacagata
      361 gtagtggtaa tcataggggc ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001045             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:20725:5940
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001045
VERSION     KCVO01001045.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20725:5940"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..387
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73074.1"
                     /translation="DYYCDSWESSGTHVF"
     J_segment       388..421
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           93 a          136 c          128 g          102 t
ORIGIN      
        1 acatggggag gctcagaagc agagctctgg ggtgtctcca ccatggcctg gactcctctc
       61 tggctcaccc tcctcagcct ttgcacaggt tctgtggttt cttctgagct gactcaggac
      121 cctgcagtgt ctgtggcctt gggacagaca gtcaggatca cttgccaagg agacagcctc
      181 agaagctatt atgcaagctg gtaccagcag aagccaggcc aggcccctgt gctggtcgtc
      241 tatgataaga acaaccggcc cccagggatc ccagagcgat tctctggctc cagctcagga
      301 aacacagctt ccttgaccat cactggggct caggtggaag atgaggctga ctattactgt
      361 gactcctggg aaagcagcgg tacccatgtg ttcggaggtg gcaccaagtt gaccgtcctc
      421 ggtcagccta aggcttcccc cttggtcact ctgttcccg
//
LOCUS       KCVO01001046             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:14303:14890
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001046
VERSION     KCVO01001046.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14303:14890"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73075.1"
                     /translation="DYYCYSTRSSGYHGLF"
     J_segment       375..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           89 a          140 c          117 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatctct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtgcaggatg aagctgacta ctactgttac tcaactcgta
      361 gcagtggtta tcatggctta ttcggagggg ggacctggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001047             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:20478:6218
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001047
VERSION     KCVO01001047.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20478:6218"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73076.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          161 c          123 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atatactggt accaacagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001048             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:6958:11292
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001048
VERSION     KCVO01001048.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:6958:11292"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73077.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          142 c          139 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gtgggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga acgattctct ggctccaaat
      301 cagggagcgc cgccaccctg accatcagtg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001049             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:22457:6605
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001049
VERSION     KCVO01001049.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:22457:6605"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73078.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           84 a          157 c          120 g          114 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtactt ataactatgt ctcctggtac caacaacatc caggcacagc
      241 ccccaaactc atgatttttg aggtcagtga gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgttgct catatgcaga cacctacact tttgtgtttg gaggtggcac
      421 cagattgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001050             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:6385:7237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001050
VERSION     KCVO01001050.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:6385:7237"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73079.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          155 c          119 g          115 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccaa
      181 cagtgacatc ggtacttata actatgtctc ctggtaccaa cagcttccag gcacagcccc
      241 caaactcatg atttttgagg tcactgagcg gccctcaggg gtctctgatc ggttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgttgctcat atgcagacac ctatactttt gtgtttggag gtggcaccag
      421 attgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01001051             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:8759:5323
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001051
VERSION     KCVO01001051.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8759:5323"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..453
                     /note="immunoglobulin light chain variable region"
     V_region        120..453
     V_segment       120..413
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73080.1"
                     /translation="DYYCLSYDSSLNTHYIF"
     J_segment       416..453
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           97 a          166 c          118 g          110 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctc gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacacagcca ccctcagtgt ctggggcccc agggcagagg gtcaccatct
      181 cgtgcactgg gagcagctcc agcattggag gtgattttgt atcctggtac caacagctcc
      241 caggaacgac ccccaaactc ctcatctatc aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtacct cagcctccct gaccatcact gggctccaga
      361 ctgaggatga ggctgattac tactgcctgt cctatgacag cagcctgaat actcattaca
      421 tcttcggtcc tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca
      481 ctctgttccc g
//
LOCUS       KCVO01001052             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:22824:8166
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001052
VERSION     KCVO01001052.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:22824:8166"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..445
                     /note="immunoglobulin light chain variable region"
     V_region        114..445
     V_segment       114..405
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <369..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73081.1"
                     /translation="DYYCQSSDTSLNDHVLF"
     J_segment       410..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>485
                     /gene="IGLC"
BASE COUNT           96 a          161 c          117 g          111 t
ORIGIN      
        1 acatggggct gcttcatctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctcgtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacaca gccgccctca gtgtctgggg ccccagggca gagggtcacc atctcctgca
      181 ctgggagcag ctccaacatt ggaggttatt atgtatactg gtaccagcaa ctcccaggaa
      241 tggcccccaa actcctcatc tatgacaata ataagcgacc ctcaggggtt tctgaccgat
      301 tctctggctc caagtctggt acctcagcct ccctgaccat cactggactc cagactgagg
      361 atgaggctga ttattactgc caatcctctg acaccagcct aaatgatcat gtgttattcg
      421 gtggagggac ccggctgacc gtcctcggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001053             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:9789:19426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001053
VERSION     KCVO01001053.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9789:19426"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..438
                     /note="immunoglobulin light chain variable region"
     V_region        110..438
     V_segment       110..404
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73082.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       405..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>478
                     /gene="IGLC"
BASE COUNT           93 a          151 c          125 g          109 t
ORIGIN      
        1 acatggggcc tgtcatcaga atacacaatc agggacttta gtctccttgg ctgagccccg
       61 ctgtccaggg aagcagaagc ctctgagccc aggcccagga tcctgggctc aggctgccct
      121 gactcagtct ccctctgtgt ctgggtctcc tggacagtcg gtcaccattt cctgcactgg
      181 aaccagcagt gacattggtg attataaccg tgtctcctgg taccaacagc acccaggcaa
      241 agcccccaaa ctcatgattt atgaggtcag tgatcggccc tcaggggtct ctgatcgctt
      301 ctctggttcc aagtctggca acacggcctc cctgatcatc tctgggctcc aggctgagga
      361 cgaggctgat tattactgca gctcatacac aagcagtagc acttgggtat tcggcggagg
      421 gacccggctg accgtccttg gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001054             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:16918:2818
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001054
VERSION     KCVO01001054.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:16918:2818"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..392
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73083.1"
                     /translation="DYYCSSTDRSGNHVF"
     J_segment       393..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          143 c          127 g          101 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccctcctc actttctgca caggctctgc agcctcctat gagctgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg
      181 cattgccaga aaaatatgct tattggttcc aacagaagcc aggccagtcc cctgtgctga
      241 tcatcaatga ggacagcaaa cggccctctg ggattcctga gagattctct ggctccagct
      301 cagggacagt ggccaccttg actctcagtg gggcccaggt ggaggatgag gctgactact
      361 actgttcctc aacagataga agtggtaatc atgtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001055             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:8399:16397
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001055
VERSION     KCVO01001055.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8399:16397"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73084.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          151 c          126 g          113 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttttg agcgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcttg atttatgagg tcagttatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattat tgcagctcat acgcaagtag tagtacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001056             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:17727:17032
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001056
VERSION     KCVO01001056.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17727:17032"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73085.1"
                     /translation="DYYCQSEDSSGYHWLF"
     J_segment       399..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT          103 a          134 c          128 g          102 t
ORIGIN      
        1 acatgggggg ctgtggttct aggaggaaga gctctgggtg tctcaccatg acctggacca
       61 ctgttctgct cccctttctc actctctgca caggctctga ggcctcctat gagctgacac
      121 agccaccctc agtgtcagtg tccccaggac agacggccag gatcacctgc tctggagaaa
      181 tactggcaaa aaaatatgct cagtggttcc agcagaagcc aggccaggcc cctgtgctgg
      241 tgatatataa agacagtgag aggccctcag ggatccctga gcgattctct agctccagtt
      301 cagggacaat agttaccttg accatcagtg gggcccaggc agaagatgag gctgactatt
      361 actgtcaatc agaagacagc agtggttatc attggctttt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001057             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:8376:19234
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001057
VERSION     KCVO01001057.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8376:19234"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..427
                     /note="immunoglobulin light chain variable region"
     V_region        104..427
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73086.1"
                     /translation="DYFCCSYADTYTFVF"
     J_segment       404..427
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>472
                     /gene="IGLC"
BASE COUNT           83 a          155 c          121 g          113 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttata actttgtctc ctggtaccaa caacatccag gcacagcccc
      241 caaactcatg atttatgagg tcaatcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctcaaagtct ggcaacacgg cctccctgac cgtctccggg gtccaggctg aggacgaggc
      361 tgattatttc tgctgctcat atgcagacac ctacactttt gttttcggaa gtggcaccag
      421 gttgaccgtc gtcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01001058             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:21997:10414
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001058
VERSION     KCVO01001058.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:21997:10414"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73087.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       396..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          146 c          132 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgaa ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaacc
      181 ttggagataa atatctacac tggtaccacc agaagccagc gcaggcccct gtgctggtca
      241 tctactatga tagtgaccgg ccctcatgga tccctgagcg attctctggg tccaagtcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtaat aatgatcata tctttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001059             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:7917:14577
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001059
VERSION     KCVO01001059.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7917:14577"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73088.1"
                     /translation="DYYCHSLDTSGNDVF"
     J_segment       378..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           88 a          140 c          117 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttactggtt ccagcagaag ccaggccagt cccctgtggt gatcatctat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgtcat tcattagata
      361 ccagtggtaa tgatgttttc ggcgggggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001060             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:5543:14562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001060
VERSION     KCVO01001060.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:5543:14562"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..454
                     /note="immunoglobulin light chain variable region"
     V_region        130..454
     V_segment       130..416
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73089.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       420..454
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT           98 a          151 c          135 g          108 t
ORIGIN      
        1 acatggggaa gagaagccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactccccc tcctcacttt ctgcacaggc
      121 tctgcagcct cctatgagct gacacagcca ccctcggtgt cagtgtcccc aggacagacg
      181 gccacgatca cctgctctgg agatgcattg ccaaaaaagt ttgcttattg gttccagcag
      241 aagccaggcc agtcccctct gctgatcatc tatgaggaca gcagacggcc ctctgggatc
      301 cctgagagat tctctggctc cagttcaggg acagtggcca ccttgactat cagtggggcc
      361 cagggggagg atgaagctga ctactactgt tattcaatgg atagcagtgg tactcagagc
      421 atcttcggtg ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc
      481 actctgttcc cg
//
LOCUS       KCVO01001061             517 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:23316:13987
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001061
VERSION     KCVO01001061.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 517)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23316:13987"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    149..479
                     /note="immunoglobulin light chain variable region"
     V_region        149..479
     V_segment       149..442
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <404..>451
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73090.1"
                     /translation="DYYCAAWDNSLSSPLF"
     J_segment       445..479
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        480..>517
                     /gene="IGLC"
BASE COUNT          105 a          161 c          134 g          117 t
ORIGIN      
        1 acatggggag agtatgaaga cagggagagt ttatggggaa gctcaccttc agctgcgggt
       61 acagaaggca ggactcagga taatctccag catggcctgg ttccctctcg tcctcaccct
      121 cctcactcac tgtgcagggt cctgggccca gtctgtgctg actcagccac cctcaacgtc
      181 tggggctccc gggcagagtg tcaccatgtc ttgctctgga agcagctcca acattggaag
      241 taattatgta tactggtacc agcagctccc aggaacggcc cccaaactcc tcatctattt
      301 tagtaatcag cgaccctcag gggtccctga ccgattctct gcctctaagt ctggcacctc
      361 agcctccctg gccatcactg gtctccgatc tgaggatgag gctgattatt actgtgcagc
      421 atgggataac agcctgagca gtcccttatt cggaggaggg acccggctga ccgtcctagg
      481 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001062             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:14759:12386
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001062
VERSION     KCVO01001062.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14759:12386"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73091.1"
                     /translation="EYYCCSYADIYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          161 c          119 g          109 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg cctcaggctg ccctgactca
      121 gcctcggtca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca cgggcaccag
      181 cagtgacatc ggtggttaca actttgtctc ctggttccaa caccatccag acacagcccc
      241 caaactcctg atttatgagg tcactcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgagtattac tgctgttcat atgcagacat ctacacattt gtgttcggaa gaggcaccaa
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01001063             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:18522:12308
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001063
VERSION     KCVO01001063.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18522:12308"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..411
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73092.1"
                     /translation="DYYCGAWDSSLSVRLF"
     J_segment       415..450
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           92 a          156 c          131 g          109 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggaccc cgggcagagg gtcaccatct
      181 cgtgcactgg gagcagctcc aacattggag gttattttgt atactggtac cagcagttcc
      241 caggaacagc ccccaaactc ctcatctatg acaataataa gcgaccctca gggatttctg
      301 accgattctc tggctccaag tctggtacct cagcctccct gaccatcact gggctccagc
      361 ctggggatga ggctgattat tactgcggag catgggatag cagcctgagt gttcgcttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCVO01001064             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:11514:10698
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001064
VERSION     KCVO01001064.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:11514:10698"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73093.1"
                     /translation="DYYCQVWDSSSDHCLL"
     J_segment       394..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          142 c          140 g           97 t
ORIGIN      
        1 acatgggggc tggcctcggg aagcagcctt ggcggtgcct cagccatggc cgggaccctt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg tctcctatga cctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaat
      181 gttggaagtg aatatgtgca ctggtaccaa cagaggccac cgcaggcccc tgtggtggtc
      241 atccattata atagtgaccg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtgatcat tgtttattgg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001065             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:16395:4816
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001065
VERSION     KCVO01001065.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:16395:4816"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73094.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          160 c          118 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcagtg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001066             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:23893:15122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001066
VERSION     KCVO01001066.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:23893:15122"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73095.1"
                     /translation="DYYCYSADSSGTGLF"
     J_segment       384..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           93 a          142 c          125 g           99 t
ORIGIN      
        1 acatggggtg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactcccca tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcgttgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agatgcattg
      181 ccacaaaaat atgcttattg gtgccagcag aaaccaggcc agtcccctgt ggtgatcatc
      241 tatgaggaca gcaaacggcc ctctgggatc cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cagtggggcc caggtggagg atgaagctga ctactactgt
      361 tactcagcag acagcagtgg tactggctta ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001067             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:10881:7856
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001067
VERSION     KCVO01001067.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:10881:7856"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..451
                     /note="immunoglobulin light chain variable region"
     V_region        130..451
     V_segment       130..414
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73096.1"
                     /translation="ADYCYSTDSSSNHGLF"
     J_segment       415..451
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        452..>489
                     /gene="IGLC"
BASE COUNT          103 a          148 c          133 g          105 t
ORIGIN      
        1 acatggggaa gagaagccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactccccc tcctcacttt ctgcacaggc
      121 tctgcagcct cctatgagct gacacagcca ccctcggtgt cagtgtcccc aggacagacg
      181 gccaggatca cctgctctgg agatgcattg ccaaaaaaat atgcttgttg gttccagcag
      241 aagccaggcc agtcccctgt attgatcatc tatgaggaca agaaacggcc ccctgggatc
      301 cctgagagat tctctggctc cagctcaggg acagtggcca ccttgactat cagtggggcc
      361 caggtggagg atgaagctga ctactgttac tcaacagata gcagttctaa tcatggctta
      421 ttcggaggag ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact
      481 ctcttcccg
//
LOCUS       KCVO01001068             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:16932:11841
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001068
VERSION     KCVO01001068.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16932:11841"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..368
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73097.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           96 a          141 c          113 g           96 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gtagcctcct atgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggta ccagcagaaa ccaggccagt cccctatgct gatcatctat gaggacaaca
      241 aacggccctc tgggatccct gaaagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcac tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 acagtggtca gggctcattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001069             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:16312:15563
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001069
VERSION     KCVO01001069.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16312:15563"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73098.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          155 c          130 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccggga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagtaac agtgtgtcct ggtacctgca gctcccagaa
      241 acggctccca aactcctcat ctattataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cccgtcagcc tccctggcca tcagtgggct cgagaccgaa
      361 gatgaggctg attattactg cgcagtatgg gatgatagcc tgagcggtgt gttgttcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01001070             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:9520:15475
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001070
VERSION     KCVO01001070.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:9520:15475"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..434
                     /note="immunoglobulin light chain variable region"
     V_region        101..434
     V_segment       101..397
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73099.1"
                     /translation="DYYCQSADGSYNPLF"
     J_segment       400..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          153 c          127 g          104 t
ORIGIN      
        1 acatgggggt ggctcaggaa gcagagcctg gagcgtctcc accatggcct gggctccact
       61 cctcctcacc ctcctcgctc actgcacagg gtcttgggct gaggttgtgt tcactcagcc
      121 ccattctgtg tcggggtctc cggggcagac agtcaccatc tcctgtaccc gcagcagtgg
      181 cagcattgac agtcaatatg tgcagtggta ccagcagcgc ccggacagtg ccccaaccac
      241 agtgattgac aaagataacc aaagaccctc tggggtccct gatcggtttt ctggctccat
      301 cgacagctcc tccaagtctg cctcgctcac catctctggg ctgaagtctg aggacgaggc
      361 tgactactac tgtcagtctg ctgatggtag ttacaatccg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001071             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:17969:17870
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001071
VERSION     KCVO01001071.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:17969:17870"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..424
                     /note="immunoglobulin light chain variable region"
     V_region        102..424
     V_segment       102..383
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73100.1"
                     /translation="DYYCQVWDSSSDHWVF"
     J_segment       389..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>464
                     /gene="IGLC"
BASE COUNT           84 a          146 c          140 g           94 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactgcacag gctctgcggt ctcctatgag ctgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggcccggat cacctgtggg ggagacaaca
      181 ttggaagtaa aagtgtgcag tggttccagc agaagccacc gcaggcccct gtgctggtca
      241 tttatggtga tatcgaacgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg gaatgaggct gactattact
      361 gtcaggtatg ggacagtagt agtgatcatt gggtattcgg cggagggacc cggctgaccg
      421 tcctcggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001072             514 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:12752:15822
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001072
VERSION     KCVO01001072.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 514)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12752:15822"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    146..476
                     /note="immunoglobulin light chain variable region"
     V_region        146..476
     V_segment       146..440
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <404..>448
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73101.1"
                     /translation="DYYCTSYASTTTWLF"
     J_segment       441..476
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        477..>514
                     /gene="IGLC"
BASE COUNT           94 a          168 c          139 g          113 t
ORIGIN      
        1 acatggggag gcagagggga taagacaggg ctgggggcag gtccagtgct gggatctcag
       61 gaggcagcac tctcaggacg tctccaccat ggcctgggct ctgctcctcc tcaccctcct
      121 cactcagggc acaggatcct gggctcaggc tgccctgact cagtctccct ctgtgtctgg
      181 gtctcctgga cagtcggtca ccatttcctg cactggaacc agcagtgaca ttggtggtta
      241 taaccgtgtc tcctggtacc aacagcaccc aggcaaagcc cccaaactca tgatttttga
      301 cgtcagtgat cggccctcag gggtctctga tcgcttctct ggttccaagt ctggcaacac
      361 ggcctccctg atcatctctg ggctccaggc tgaggacgag gctgattatt actgcacctc
      421 atacgcaagc actaccactt ggctattcgg cggagggacc cgcctgaccg tcctaggtca
      481 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001073             309 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:18854:17544
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001073
VERSION     KCVO01001073.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 309)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18854:17544"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    73..271
                     /note="immunoglobulin light chain variable region"
     V_region        73..271
     V_segment       73..231
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <196..>243
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73102.1"
                     /translation="DYYCYSTISSGNERIF"
     J_segment       238..271
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        272..>309
                     /gene="IGLC"
BASE COUNT           61 a           96 c           78 g           74 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacagaagcc aggccagtcc cctgtgttga tcatctatga ggacagcaaa
      121 cggccctctg ggatccctga gagattctct ggctccacct tgactatcag tggggcccag
      181 gtggaggatg aagctgacta ctactgttac tcaacaatta gtagtggtaa tgaaaggatc
      241 ttcggtgctg ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact
      301 ctgttcccg
//
LOCUS       KCVO01001074             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:12621:11847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001074
VERSION     KCVO01001074.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12621:11847"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73103.1"
                     /translation="DYFCYSTDSSGNALF"
     J_segment       374..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           91 a          141 c          115 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct ctgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatttg
      181 cttattggta ccagcagaaa ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta cttctgttac tcaacagaca
      361 gcagtggtaa tgccttattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001075             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:4693:16295
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001075
VERSION     KCVO01001075.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:4693:16295"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73104.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          143 c          139 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctcactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggaggca
      181 atgttggaag tgaatatgtc cactggtatc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatctatta taatactgac cggccctcag ggttccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt aggagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001076             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:9421:12162
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001076
VERSION     KCVO01001076.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:9421:12162"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73105.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           92 a          140 c          115 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatcaat gagtacagca
      241 aacggccctc tgggatccct gagagaatct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtagaggatg aagctgacta ctactgttcc tcaacagata
      361 gtagtggtaa tcatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001077             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:2822:13444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001077
VERSION     KCVO01001077.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:2822:13444"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73106.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          156 c          123 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac tagtacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001078             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:16952:19922
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001078
VERSION     KCVO01001078.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16952:19922"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73107.1"
                     /translation="DYYCYSADSSGNGLF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           95 a          139 c          125 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcgtatt ggtatcagca gaaaccaggc cagtcccctg tgcatatcat
      241 ctatgaggac agcaagcggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtgtggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtaatggctt attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001079             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:8441:17167
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001079
VERSION     KCVO01001079.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8441:17167"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..434
                     /note="immunoglobulin light chain variable region"
     V_region        105..434
     V_segment       105..397
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73108.1"
                     /translation="DYYCGSYRGGSTYIF"
     J_segment       399..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>473
                     /gene="IGLC"
BASE COUNT           81 a          157 c          124 g          111 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcgggacgt ctccaccatg gcttgggctc
       61 tggtcctcct caccctcctc actcagggca caggatcctg ggctcagtct gccctgactc
      121 agcctccctc agtgtccaag tctcttggac agtccgtcac catctcctgt actggaacca
      181 gcagtgacat tggtggttat aacggtgtct cctggtacca gcagcactca ggcacggccc
      241 ccagactctt gatttatgag gtcagtaagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaagatgagg
      361 ctgactatta ctgcggctcc tataggggtg gaagcaccta catcttcggt gttgggaccc
      421 gtctcaccgt cctacgtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001080             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:13240:7401
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001080
VERSION     KCVO01001080.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:13240:7401"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..439
                     /note="immunoglobulin light chain variable region"
     V_region        115..439
     V_segment       115..402
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73109.1"
                     /translation="DYYCQVWDSSSDHCLL"
     J_segment       406..439
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           89 a          148 c          142 g           98 t
ORIGIN      
        1 acatggggga acctgcccag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg
       61 gccgggaccc ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat
      121 gacctgactc agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt
      181 gggggagaca atgttggaag tgaatatgtg cactggtacc aacagaggcc accgcaggcc
      241 cctgtggtgg tcatccatta taatagtgac cggccctcag ggatccctga gcgattctct
      301 ggctccaaat cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag
      361 gctgactatt actgtcaggt gtgggacagt agtagtgatc attgtttatt gggaggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001081             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:22983:5512
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001081
VERSION     KCVO01001081.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22983:5512"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..401
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73110.1"
                     /translation="EYYCCSYADIYTFVF"
     J_segment       402..436
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           83 a          162 c          119 g          110 t
ORIGIN      
        1 acatggggct ggggtctcag acggcagcgc tctcgggaca tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct ggcctcaggc tgccctgact
      121 cagcctcggt cagtgtctgg gtctcctgga cagtcggtca ccatctcctg cacgggcacc
      181 agcagtgaca tcggtggtta caactttgtc tcctggttcc aacaccatcc agacacagcc
      241 cccaaactcc tgatttatga ggtcactcag cggccctcag gggtctctga tcgcttctct
      301 ggctccaagt ctggcaacac ggcctccctg accatctctg ggctccaggc tgaggacgag
      361 gctgagtatt actgctgttc atatgcagac atctacacat ttgtgttcgg aagaggcacc
      421 aagttgaccg tcctcggtca gcccaaggct tcccccttgg tcactctgtt cccg
//
LOCUS       KCVO01001082             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:23401:13431
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001082
VERSION     KCVO01001082.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23401:13431"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..435
                     /note="immunoglobulin light chain variable region"
     V_region        111..435
     V_segment       111..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <360..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73111.1"
                     /translation="DYYCQVWDSSSAHWVF"
     J_segment       398..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           84 a          151 c          141 g           97 t
ORIGIN      
        1 acatggggct gcccagcctg gcctcgggaa gcagccttgg cggtgcctca gccatggccg
       61 ggacccttct cctcctcggc ctccttgctc actgcacagg ctctgcggtc tcctatgagt
      121 tgactcagcc acgctcagtg tccgtgtccc caggacagac ggcccggatc acctgtgggg
      181 gagacaacat tggaagtaaa agtgtgcagt ggttccagca gaagccaccg caggcccctg
      241 tgctggtcat ttatgctgat agcgaacggc cctcagggat ccctgagcga ttctctggct
      301 ccaactcagg aaataccgcc accctgacca tcaccggggt cgaggccggg aatgaggctg
      361 actattactg tcaggtgtgg gacagtagta gtgctcattg ggttttcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001083             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:11814:10403
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001083
VERSION     KCVO01001083.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11814:10403"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..433
                     /note="immunoglobulin light chain variable region"
     V_region        106..433
     V_segment       106..396
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73112.1"
                     /translation="DYYCLLYYSGAYIF"
     J_segment       397..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           99 a          158 c          112 g          102 t
ORIGIN      
        1 acatggggag ctctggagcc agagatccct tccaatacca gcaccatggc ctggactctg
       61 ctcctcctcc agttcctcct cacttgctgc ccagggtcca attctcaggc tgtagtgact
      121 caggagccct caatgactgt gtccccagga gggacagtca ctctcacctg tggctccaac
      181 actggagcag tcaccagtga ctactatcca aactggttcc agcagacacc tggacaagtc
      241 cccaggggac tgatttacaa tacaaacaac aaacactcct ggacccctgc ccggttctca
      301 ggctccctcg ctgggggcaa agctgccctg acactgtcag atgcacagcc cgaggacgag
      361 gctgactatt actgtttgct gtactatagt ggtgcttaca tcttcggtgc tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCVO01001084             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:6571:17415
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001084
VERSION     KCVO01001084.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6571:17415"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..289
                     /note="immunoglobulin light chain variable region"
     V_region        8..289
     V_segment       8..251
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <214..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73113.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       253..289
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>327
                     /gene="IGLC"
BASE COUNT           67 a          100 c           83 g           77 t
ORIGIN      
        1 acatgggggg tcaccatctc ctgcactggg agcagttcca acattggagg ttattatgtg
       61 cagtggtacc agcagcttcc aggaacggcc cccaaactcc tcatgtatga aaataataag
      121 cgaccctcag gggtttctga tcgattctct ggctcccagt ctggtacctc agcctccctg
      181 accatcactg gactccagtc tgaggatgag gctgattatt actgccagtc ctatgacagc
      241 agcctgagtg ccgtgttatt cggagcaggg acccggctga ccgtcctagg tcagcccaag
      301 gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001085             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:6187:9537
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001085
VERSION     KCVO01001085.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:6187:9537"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..426
                     /note="immunoglobulin light chain variable region"
     V_region        99..426
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73114.1"
                     /translation="DYYCYSTENTDTHRGFF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           91 a          145 c          126 g          102 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatctc ctgctctgga gatgcattgc
      181 caaagaaatt tgcttcttgg ttccagcaga agccaggcca gtcccctgtg ctgatcatct
      241 atgaggacag caaacggccc tctgggatcc ctgagagatt ctctggctcc agttcaggga
      301 cagtggccac cttgactatc ggtggggccc aggtggagga tgaagctgac tactactgtt
      361 actcaacaga gaacactgat actcataggg gcttcttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001086             410 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:18220:13631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001086
VERSION     KCVO01001086.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 410)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:18220:13631"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    42..372
                     /note="immunoglobulin light chain variable region"
     V_region        42..372
     V_segment       42..336
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <300..>344
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73115.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       337..372
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        373..>410
                     /gene="IGLC"
BASE COUNT           77 a          138 c          101 g           94 t
ORIGIN      
        1 acatgggcac cctcctcact cagggcacag gatcctgggc tcaggctgcc ctgactcagt
       61 ctccctctgt gtctgggtct cctggacagt cggtcaccat ttcctgcact ggaaccagca
      121 gtgacattgg tggttataac cgtgtctcct ggtaccaaca gcacccaggc aaagccccca
      181 aactcatgat ttatgacgtc agtgatcggc cctcaggggt ctctgatcgc ttctctggtt
      241 ccaagtctgg caacacggcc tccctgatca tctctgggct ccaggctgag gacgaggctg
      301 attattactg cagctcatac acaagcacta ccacttggct attcggcgga gggacccgcc
      361 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001087             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:12108:13579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001087
VERSION     KCVO01001087.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:12108:13579"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73116.1"
                     /translation="DYYCGSYGSGNIFLF"
     J_segment       407..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           82 a          154 c          128 g          111 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagcg ctctcgggac gtctccacca tggcttgggc
       61 tctggtcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagt ctgccctgac
      121 tcagcctccc tcagtgtcca agtctcttgg acagtccgtc accatctcct gcactggaac
      181 caaaaatgac attggtgggt ttaacggtgt ctcctggtac cagcgacact caggcacagc
      241 ccccggactc ctactttatg aggtcaatag gcggccctca ggggtctcta atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatttct gggctccagg ctgaggatga
      361 ggctgattat tactgcggct cgtacgggag tggaaacatt tttttgttcg gaggcgggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001088             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:18143:7053
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001088
VERSION     KCVO01001088.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18143:7053"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73117.1"
                     /translation="DYYCSSYADSYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           81 a          157 c          122 g          112 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtacttatg actatgtctc ctggtaccaa cagcatccag gcacagcccc
      241 caaactcatg atttttgagg tcagtgagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgttcctcat atgcagacag ctacactttt gtgttcgggg gtggcaccaa
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01001089             494 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:26163:12716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001089
VERSION     KCVO01001089.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 494)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:26163:12716"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..456
                     /note="immunoglobulin light chain variable region"
     V_region        123..456
     V_segment       123..416
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73118.1"
                     /translation="DYYCLSYDSSLSAHYIF"
     J_segment       419..456
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>494
                     /gene="IGLC"
BASE COUNT           95 a          165 c          122 g          112 t
ORIGIN      
        1 acatgggggg ggaagctctg cttcagctgt gggcacagga ggcagcactc aggacagtct
       61 ccagcatggc ctcgtctcct ctcctcctca cccttctcat tcactgcaca gggtcctggg
      121 cccagtctgt gctgacacag ccaccctcag tgtctggggc cccagggcag acggtcacca
      181 tctcgtgcac tgggagcagc tccagcattg gaggtgatta tgtatcctgg taccaacagc
      241 tcccaggaac gacccccaaa ctcctcatct atcaaaataa taagcgaccc tcaggggttt
      301 ctgaccgatt ctctggctcc aagtctggtt cctcagtctc cctgaccatc actgggctcc
      361 agactgagga tgaggctgat tactactgcc tgtcctatga cagcagtctg agtgctcatt
      421 acatcttcgg tcctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg
      481 tcactctgtt cccg
//
LOCUS       KCVO01001090             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:12316:19277
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001090
VERSION     KCVO01001090.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12316:19277"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73119.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           91 a          139 c          117 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgtca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gagagaatct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gtagtggtaa tcatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001091             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:16803:7911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001091
VERSION     KCVO01001091.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16803:7911"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..392
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73120.1"
                     /translation="DYYCFSSDRSSDHWVF"
     J_segment       393..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>467
                     /gene="IGLC"
BASE COUNT           92 a          141 c          129 g          105 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccctcctc actttctgca caggctctgc agcctcctat gagctgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg
      181 cattgccaaa aaaatatgct tattggttcc agcagaagcc aggccagtcc cctgtgctga
      241 tcatctatga ggacaggaaa cggtcctctg ggatccctga gagattctct ggctccagct
      301 cagggacaat ggccaccttg actatcagtg gggcccaggt ggaggatgaa ggtgactact
      361 actgtttctc atcagataga agttctgatc attgggtgtt cggcggaggg acccggctga
      421 ccgtcccagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001092             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:15761:4945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001092
VERSION     KCVO01001092.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15761:4945"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73121.1"
                     /translation="DYYCYSTDSSGNHIF"
     J_segment       388..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           94 a          145 c          118 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgacgac agtaaacggc cctctgggat ccctgataga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gatagcagtg gtaatcacat cttcgctact gggacccggc tcaccgtcct
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01001093             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:20087:13179
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001093
VERSION     KCVO01001093.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20087:13179"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..381
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73122.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       385..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           98 a          144 c          120 g           97 t
ORIGIN      
        1 acatggggtg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactcccca tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcgttgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agatgcattg
      181 ccagaaaaat atgcttattg gtaccagcag aaaccaggcc agtcccctat gctgatcatc
      241 tatgaggaca acaaacggcc ctctgggatc cctgaaagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cactggggcc caggtggagg atgaagctga ctactactgt
      361 tactcagcag acaacagtgg tcagggctca ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001094             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:11318:4577
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001094
VERSION     KCVO01001094.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:11318:4577"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..454
                     /note="immunoglobulin light chain variable region"
     V_region        122..454
     V_segment       122..413
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73123.1"
                     /translation="NYYCLSYDTSLSGHGLF"
     J_segment       418..454
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>493
                     /gene="IGLC"
BASE COUNT           95 a          165 c          122 g          111 t
ORIGIN      
        1 acatgggggg gaagctctgc ttcagctgtg ggcacaggag gcagcactca ggactgtctc
       61 caacatggcc tcgtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc
      121 ccagtctgtg ctgacacagc caccctcact gtctggggcc ccaggacaga gggtcaccat
      181 ctcgttcact gggagcagct ccaacattgg aggttattct gtatcctggt gccagaaatt
      241 cccagaaacg acccccaacc tcctcgacta tcaagataat aagcgaccct caggggtttc
      301 tgaccgattc tctggctcca agtctggtcc ctcagcctcc ctgaccatca ctgggctcca
      361 gactgaggct gggactaatt attactgcct gtcgtatgac accagcctga gtggtcatgg
      421 cttgttcgga ggaggaaccc ggctgaccgt cctacgtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCVO01001095             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:19805:16411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001095
VERSION     KCVO01001095.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:19805:16411"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73124.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          157 c          122 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggttccaa cagcacccag gcaaagcccc
      241 caaactcatg atttgtgacg tcagtaatcg gccctcaggg gtctctgctc gcttctctgg
      301 ttccaagtct ggcaatacgg cctccctgat catctctgga ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcag tagcacttgg gttttcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001096             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:9223:13824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001096
VERSION     KCVO01001096.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9223:13824"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..381
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73125.1"
                     /translation="DYYCQVWDSITAQWVF"
     J_segment       390..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           83 a          147 c          139 g           95 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactgcacag gctttgcggt ctcctatgag ctgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggcccggat cacctgtggg ggagacaaca
      181 ttggaagtaa aagtgtgcag tggttccagc agaggccacc gcaggcccct gtgctggtca
      241 tttatactga taaccagcgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg gaatgaggct gactattatt
      361 gtcaggtgtg ggacagtatt actgctcagt gggtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001097             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:16185:5852
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001097
VERSION     KCVO01001097.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:16185:5852"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73126.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       394..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          141 c          137 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag actctgcggt ctcctatgac ctgactcagc
      121 caccctcggt ttcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaatg
      181 ttggaagtga atatgtgcac tggtaccaac agaaaccagc gcaggcccct gtggtggtca
      241 tccattataa tagtgaccgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatcatt gtgtattggg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001098             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:10060:3516
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001098
VERSION     KCVO01001098.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:10060:3516"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..400
                     /gene="IGLV8-111"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73127.1"
                     /translation="DYYCAVYMGSGIDVF"
     J_segment       401..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           90 a          148 c          124 g          113 t
ORIGIN      
        1 acatggggga gaagcctgag agcacttggc cttcataagt gtccccacca tggcctggat
       61 gatgcttctc ctcggactcc ttgcttatgg ctcaggagtg gattctgaga ctgtggtgac
      121 ccaggagcca tcgttgtcag tgtcccctgg aggaacagtc acactcacct gtggcctgag
      181 ctctggctca gtctctaccg ataactaccc cagctggtac cagcagaccc caggccaggc
      241 tccacgcatg ctcctcttca acacaaacac tcgcccttct ggggtcccta ctcgcttctc
      301 tggctccatc cttgggaaca aagctgccct caccgtcacg ggggctcagg cagacgatga
      361 atctgattat tactgtgcgg tgtacatggg tagtggcatt gatgtgttcg gaagtggcac
      421 caagttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001099             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:29076:13033
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001099
VERSION     KCVO01001099.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:29076:13033"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73128.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           92 a          141 c          117 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatctcct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag gcaggccagt cccctgtgct gatcatctat gaggacaaca
      241 aacggccctc tgggatccct gagagattct ctggctccag ttcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagata
      361 acagtgatac tcataggggc ttcttcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001100             430 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:27351:8823
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001100
VERSION     KCVO01001100.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 430)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:27351:8823"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..392
                     /note="immunoglobulin light chain variable region"
     V_region        101..392
     V_segment       101..355
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <317..>364
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73129.1"
                     /translation="DYYCYSTVSSGNDRIF"
     J_segment       359..392
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        393..>430
                     /gene="IGLC"
BASE COUNT           85 a          134 c          115 g           96 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatccc
      241 tgagagactc tctggctcca gctcagggac agtggccacc ttgactatca gtggggccca
      301 ggtggaggat gaagctgact actactgtta ctcaacagtt agcagtggta atgataggat
      361 cttcggtgct gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac
      421 tctgttcccg
//
LOCUS       KCVO01001101             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:19050:11200
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001101
VERSION     KCVO01001101.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:19050:11200"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73130.1"
                     /translation="DYFCQVWDSTNKYVLF"
     J_segment       397..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           90 a          145 c          134 g           99 t
ORIGIN      
        1 acatggggct gcctgacttt gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgctcactgc acaggttttg tggcctccta tgagctgact
      121 cagccaccct cggtgtcggt gtccccagga cagacagcca ggatcacctg tgggggagac
      181 aacattggac atgaaagtgt gcactggtac caacagaagc caccgcaggc ccctgtgttg
      241 gtcatatatt ctggtggcga acggccctca gggatccctg agcgattctc tgccaccatg
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 ttctgtcagg tctgggacag tactaataaa tacgtattat tcggaggagg gacccgactg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001102             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:4617:13575
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001102
VERSION     KCVO01001102.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:4617:13575"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73131.1"
                     /translation="DYYCSSTDSRDNHRVF"
     J_segment       389..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           94 a          142 c          127 g           99 t
ORIGIN      
        1 acatggggtg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactccccc tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agatgcattg
      181 ccagaaaaat atgcttattg gttccagcag aagccaggcc agtcccctgt gctgatcgtc
      241 tatgaggaca acaaacggcc ctctgggatc cctgagagat tctctggctc cagctcaggg
      301 acagtggcca cgttgactat cagtggggcc caggtggagg atgaagctga ctactactgt
      361 tcctcaacag atagcaggga taatcatagg gtattcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001103             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:12054:15031
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001103
VERSION     KCVO01001103.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:12054:15031"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73132.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       401..435
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           83 a          156 c          120 g          114 t
ORIGIN      
        1 acatggggtg gggtctcaga cggcagcgct ctcgggacat ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctcgctc agtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cggtacttat aactatgtct cctggtacca acagcatcca ggcacagccc
      241 ccaaactcat gatttttgag gtcagtgagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgttgctca tatgcagaca cctacacttt tgtgtttgga ggtggcacca
      421 gattgaccgt cctcggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01001104             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:8142:4252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001104
VERSION     KCVO01001104.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8142:4252"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73133.1"
                     /translation="DYYCGAWDSSLNTRLF"
     J_segment       412..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           92 a          158 c          128 g          107 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggaccccgg gcagagggtc accatctcgt
      181 gcactgggag cagctccaac attggaggtt atcttgtata ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctatgaca ataataagcg accctcaggg atttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagcctg
      361 gggatgaggc tgattattac tgcggagcat gggatagcag cctgaatact cgcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001105             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:20812:12617
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001105
VERSION     KCVO01001105.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20812:12617"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73134.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          162 c          125 g          107 t
ORIGIN      
        1 acatgggggg gtccgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001106             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:11670:9450
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001106
VERSION     KCVO01001106.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11670:9450"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..433
                     /note="immunoglobulin light chain variable region"
     V_region        109..433
     V_segment       109..390
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73135.1"
                     /translation="DYYCQVWDSSSAHWVF"
     J_segment       396..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           83 a          150 c          141 g           97 t
ORIGIN      
        1 atggggctgc ccagcctggc ctcgggaagc agccttggcg gtgcctcagc catggccggg
       61 acccttctcc tcctcggcct ccttgctcac tgcacaggct ctgcggtctc ctatgagttg
      121 actcagccac gctcagtgtc cgtgtcccca ggacagacgg cccggatcac ctgtggggga
      181 gacaacattg gaagtaaaag tgtgcagtgg ttccagcaga agccaccgca ggcccctgtg
      241 ctggtcattt atgctgatag cgaacggccc tcagggatcc ctgagcgatt ctctggctcc
      301 aactcaggaa ataccgccac cctgaccatc accggggtcg aggccgggaa tgaggctgac
      361 tattactgtc aggtgtggga cagtagtagt gctcattggg ttttcggcgg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001107             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:16705:9077
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001107
VERSION     KCVO01001107.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16705:9077"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..437
                     /note="immunoglobulin light chain variable region"
     V_region        89..437
     V_segment       89..397
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73136.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       400..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           94 a          155 c          119 g          107 t
ORIGIN      
        1 acatgggggg gggaaagagg ctgtgtccac catggcctgg actcctctcc tcctcctgct
       61 cctctctcac tgcacaggtt ccctctccaa gcctatgctg actcagccgg cctccctctc
      121 agcatctcct ggagcatcag ccagtctcac atgcaccttc agcggtggca tcaatgttgc
      181 tggctaccac atacactggt accagcagaa gccagggagt cctccccggt atcttctgag
      241 atacaaatca gactcagata agggccaggg ctctggagtc cccagccgct tctctggatc
      301 caaagatggt tcagcgaaca cagggatttt acgcatctct gggctccagt ctgaggatga
      361 ggctgactat tactgtgcca ttggacacag cagcggtgat tacatcttcg gtgctgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCVO01001108             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:12747:3245
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001108
VERSION     KCVO01001108.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12747:3245"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73137.1"
                     /translation="DYYCGSYRRGTTWIF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           82 a          156 c          126 g          109 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcgct ctcgggacgt ctccaccatg gcttgggctc
       61 tggtcctcct caccctcctc actcagggca caggatcctg ggctcagtct gccctgactc
      121 agcctccctc agtgtccaag tctcttggac agtccgtcac catctcctgc actggaacca
      181 gcagtgacat tggtgattat aacgctgtct cctggtacca gcagtactca ggcacagccc
      241 ccagactcct gatttatgag gtcactcagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggctacacg gcctccctga ccatttctgg gctccaggct gaggatgagg
      361 ctgattatta ctgcggctca tataggaggg gaaccacttg gatattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001109             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:27459:11784
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001109
VERSION     KCVO01001109.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:27459:11784"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73138.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       379..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           92 a          140 c          116 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaagtatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaagacgaca
      241 aacggccctc tgggatccct gagagaatct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaatagata
      361 gtagtggtag tcatagcgtc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001110             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:17439:13819
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001110
VERSION     KCVO01001110.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17439:13819"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73139.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          161 c          123 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggagtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001111             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:4968:13377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001111
VERSION     KCVO01001111.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4968:13377"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..447
                     /note="immunoglobulin light chain variable region"
     V_region        114..447
     V_segment       114..407
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73140.1"
                     /translation="DYYCSLWDSRLSSRLF"
     J_segment       415..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           92 a          156 c          127 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccgggca gagggtcacc atctcctgca
      181 ctgggaccag ctccaacatc ggggcgaatt attatgtttc ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctatgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catctctgga ctccaatctg
      361 aggatgaggc tgattattac tgctcactat gggatagcag gctgagtagt cggttattcg
      421 gcggagggac ccgactgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001112             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:14521:10067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001112
VERSION     KCVO01001112.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:14521:10067"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..426
                     /note="immunoglobulin light chain variable region"
     V_region        97..426
     V_segment       97..389
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73141.1"
                     /translation="DYHCQSYDSSLSAVLF"
     J_segment       391..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>465
                     /gene="IGLC"
BASE COUNT           89 a          150 c          125 g          101 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac gcagccgccc
      121 tcagtgtctg gggcgcccgg gcagagggtc accatctcct gcactgggag cagctccaac
      181 attggaggtt attatgtgca gtggtaccag caagttccag gaacggcccc caaagctctc
      241 atctatgaaa ataataagcg accctcaggg gtttctgatc gattctctgg ggcccagtct
      301 ggtacctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgattatcac
      361 tgccagtcct atgacagcag cctgagtgcc gtgttattcg gaggggggac ccggctgacc
      421 gtcctaagtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001113             513 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:18812:16905
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001113
VERSION     KCVO01001113.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 513)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 513)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..513
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18812:16905"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    154..475
                     /note="immunoglobulin light chain variable region"
     V_region        154..475
     V_segment       154..435
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <403..>447
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73142.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       439..475
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        476..>513
                     /gene="IGLC"
BASE COUNT          110 a          157 c          142 g          104 t
ORIGIN      
        1 acatgggggc cccatagggc ctgggaagga ataagagaag cctagggagc ccagctgtgc
       61 tgtgggctca ggaggcagag ctctgggtgt ctcaccatgg cctggattcc tctcctactc
      121 cccatcctca ctttctgcac aggctctgca gcctcctatg agctgacaca gccaccctcg
      181 ttgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagatgc attgccagaa
      241 aaatatgctt attggtacca gcagaaacca ggccagtccc ctatgctgat catctgtgag
      301 gacagcaaac ggccctctgg gatccctgaa agattctctg gctccagctc agggacagtg
      361 gccaccttga ctatcactgg ggcccaggtg gaggatgaag ctgactacta ctgttactca
      421 gcagacaaca gtggtcaggg ctcattcgga ggagggaccc ggctgaccgt cctaggtcag
      481 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001114             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:13006:8460
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001114
VERSION     KCVO01001114.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13006:8460"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73143.1"
                     /translation="DYYCQVWDSSSDHCLL"
     J_segment       391..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           86 a          141 c          139 g           96 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggtct cctatgacct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaatgtt
      181 ggaagtgaat atgtgcactg gtaccaacag aggccaccgc aggcccctgt ggtggtcatc
      241 cattataata gtgaccggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtagtag tgatcattgt ttattgggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001115             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:19297:11463
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001115
VERSION     KCVO01001115.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:19297:11463"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73144.1"
                     /translation="DYYCQSADGSYNPLF"
     J_segment       406..440
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           88 a          155 c          129 g          106 t
ORIGIN      
        1 acatggggct ggctgtggct caggaagcag agcctggagc gtctccacca tggcctgggc
       61 tccactcctc ctcaccctcc tcgctcactg cacagggtct tgggctgagg ttgtgttcac
      121 tcagccccat tctgtgtcgg ggtctccggg gcagacagtc accatctcct gtacccgcag
      181 cagtggcagc attgacagtc aatatgtgca gtggtaccag cagcgcccgg acagtgcccc
      241 aaccacagtg attgacaaag ataaccaaag accctctggg gtccctgatc ggttttctgg
      301 ctccatcgac agctcctcca agtctgcctc gctcaccatc tctgggctga agtctgagga
      361 cgaggctgac tactactgtc agtctgctga tggtagttac aatccgttat tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001116             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:6428:9138
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001116
VERSION     KCVO01001116.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:6428:9138"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73145.1"
                     /translation="DYYCYSTDSSGNHIF"
     J_segment       386..420
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           94 a          145 c          118 g          101 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 caaaaaagta tgcttattgg ttccagcaga agccaggcca gtcccctgtg ctgatcatct
      241 atgacgacag taaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc agtggggccc aggtggagga tgaagctgac tactactgtt
      361 actcaacaga tagcagtggt aatcacatct tcgctactgg gacccggctc accgtcctag
      421 gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCVO01001117             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:10212:8503
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001117
VERSION     KCVO01001117.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10212:8503"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    139..336
                     /note="immunoglobulin light chain variable region"
     V_region        139..336
     V_segment       139..296
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <264..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73146.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       300..336
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        337..>374
                     /gene="IGLC"
BASE COUNT           72 a          121 c           99 g           82 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc cctatgctga tcatctatga ggacaacaaa cggccctctg
      181 ggatccctga aagattctct ggctccagct cagggacagt ggccaccttg actatcactg
      241 gggcccaggt ggaggatgaa gctgactact actgttactc agcagacaac agtggtcagg
      301 gctcattcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg
      361 tcactctctt cccg
//
LOCUS       KCVO01001118             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:25968:4746
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001118
VERSION     KCVO01001118.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:25968:4746"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73147.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          155 c          124 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtaatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggttg aggacgaggc
      361 tgattattac tgcagttcat acgcaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001119             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:24150:8824
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001119
VERSION     KCVO01001119.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24150:8824"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..405
                     /note="immunoglobulin light chain variable region"
     V_region        87..405
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73148.1"
                     /translation="DYYCYSSDSNADYWVF"
     J_segment       375..405
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        406..>449
                     /gene="IGLC"
BASE COUNT           90 a          139 c          119 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggttccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcatcagata
      361 gcaatgctga ttattgggtg ttcggcggag ggacccggct gaccggccca ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001120             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:7525:23660
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001120
VERSION     KCVO01001120.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7525:23660"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..400
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73149.1"
                     /translation="DYYCSSYTTSSTVFF"
     J_segment       401..437
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          157 c          118 g          114 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtatcctgg acagtcggtc accatctcct gcagtggaac
      181 cagcagtgat gttgggtact ataatgctgt gtcttggtac caacagcacc caggcacagc
      241 ccccaaactc ttgatttatg gtgtcagtag tcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctgtcaaca cggcctccct aaccatctct ggcctccagc ctgaggacga
      361 ggctgattat tactgttctt catatacaac cagcagcact gtgtttttcg gaggagggac
      421 ccgactgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001121             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:16639:12695
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001121
VERSION     KCVO01001121.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:16639:12695"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..447
                     /note="immunoglobulin light chain variable region"
     V_region        120..447
     V_segment       120..407
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73150.1"
                     /translation="EYHCFSTDSSGNHRGFF"
     J_segment       411..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           95 a          149 c          134 g          107 t
ORIGIN      
        1 acatggggag gggagcccag ctgtgctgtg ggctcaggag gcagagctct gggtgtctca
       61 ccatggcctg gattcctctc ctactccccc tcctcacttt ctgcacaggc tctgcagcct
      121 cctatgagct gacacagcca ccctcggtgt cagtgtcccc aggacagacg gccaggatca
      181 cctgctctgg agatgcattg ccaaaaaaat ttgcttcttg gttccagcag aagccaggcc
      241 agtcccctgt gctgatcatc tatgacgaca gcaaacggcc ctctgggatc cctgagagat
      301 tctctggctc cagctcaggg acagtggcca ccttgactat cattggggcc caggtggagg
      361 atgaagctga gtaccactgt ttctcaacag atagtagtgg taatcatagg ggcttcttcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001122             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:3211:12376
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001122
VERSION     KCVO01001122.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:3211:12376"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73151.1"
                     /translation="EYHCFSTDSSGNHRGLF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           92 a          142 c          116 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcactgcca aaaaaatttt
      181 cttcttggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gacgacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcat tggggcccag gtggaggatg aaactgagta ccactgtttc tcaacagata
      361 gtagtggtaa tcataggggc ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001123             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:17109:16637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001123
VERSION     KCVO01001123.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17109:16637"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73152.1"
                     /translation="DYYCQVWDSNSDHIIF"
     J_segment       397..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          144 c          138 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaga tgagtattta cactggtacc agcagaagcc agcgcgggcc cctgtgctgg
      241 tcatctacta tgatagtgac cggccctcat ggatccctga gcgattctct gggtccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt aatagtgatc atattatatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001124             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:12939:7901
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001124
VERSION     KCVO01001124.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12939:7901"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73153.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          161 c          126 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaagcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001125             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:24484:9536
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001125
VERSION     KCVO01001125.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:24484:9536"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..422
                     /note="immunoglobulin light chain variable region"
     V_region        104..422
     V_segment       104..385
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73154.1"
                     /translation="DYYCQSTDSSGFIF"
     J_segment       388..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           99 a          137 c          121 g          103 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 accaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcacaa aaatatgctc agtggttcca gcagaagcca ggccaggccc ctgtgttgct
      241 gatatttaaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacatcg attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca acggacagca gtggtttcat cttcggtgct gggacccggc tcaccgtcct
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01001126             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:17423:9518
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001126
VERSION     KCVO01001126.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17423:9518"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73155.1"
                     /translation="DYYCYSSDGSADYWVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           89 a          140 c          129 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggtt ccagttcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcatca gatggcagtg ctgattattg ggtgttcggc ggagggaccc ggctgaccgt
      421 cccaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001127             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:18628:14926
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001127
VERSION     KCVO01001127.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18628:14926"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73156.1"
                     /translation="DYYCSSTDFSGNHVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           92 a          145 c          122 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccaaca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatttcagtg gtaatcatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001128             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:23475:15912
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001128
VERSION     KCVO01001128.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:23475:15912"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73157.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       391..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           87 a          142 c          138 g           95 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggtct cctatgacct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtgtggg agacaatgtt
      181 ggaagtgaat atgtgcactg gtaccaacag aagccaccgc aggcccctgt ggtggtcatc
      241 cattataata gtgaccggcc ctcagggatc cctgaacgat tctctggccc caaatcaggg
      301 agcgccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtagtag tgatcatagt ttattgggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001129             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:19515:13264
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001129
VERSION     KCVO01001129.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19515:13264"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73158.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          142 c          137 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcattggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttctactgg
      241 tcatctatgc tgataacgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg ttttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001130             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:17868:20776
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001130
VERSION     KCVO01001130.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:17868:20776"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73159.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          137 c          142 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcattggaag tagaagtgtg cagtggtacc agcagaagcc accgcagggc cttgtagtgg
      241 tcatctatag tgatagcgaa cggccctcag ggatccctga gcgattttct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001131             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:11516:10346
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001131
VERSION     KCVO01001131.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11516:10346"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73160.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          157 c          129 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagttccaac attggaggtt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaactcctc atgtatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggtacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cctgagtgcc gtgttattcg
      421 gagcagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001132             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:2839:8029
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001132
VERSION     KCVO01001132.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:2839:8029"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..397
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73161.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       398..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           82 a          151 c          125 g          113 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcactct caggacgtct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 tctccctctg tgtctgggtc tcctggacag tcggtcacca tttcctgcac tggaaccagc
      181 agtgacattg gtggttttga gcgtgtctcc tggtaccaac agcacccagg caaagccccc
      241 aaactcttga tttatgaggt cagttatcgg ccctcagggg tctctgatcg cttctctggt
      301 tccaagtctg gcaacacggc ctccctgatc atctctgggc tccaggctga ggacgaggct
      361 gattattatt gcagctcata cgcaagtagt agtacttggg tattcggcgg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001133             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:12605:7268
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001133
VERSION     KCVO01001133.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12605:7268"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..397
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73162.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       398..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           82 a          156 c          124 g          109 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcactct caggacgtct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 tctccctctg tgtctgggtc tcctggacag tcggtcacca tttcctgcac tggaaccagc
      181 agtgacattg gtggttataa ccgtgtctcc tggttccaac agcacccagg caaagccccc
      241 aaactcatga tttgtgacgt cagtgatcgg ccctcagggg tctctgctcg cttctctggt
      301 tccaagtctg gcaatacggc ctccctgatc atctctgggc tccaggctga ggacgaggct
      361 gattattact gcagctcata cgcaagcagt agcacttggg tattcggcgg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001134             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:12805:5692
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001134
VERSION     KCVO01001134.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:12805:5692"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73163.1"
                     /translation="EYYCSSYADIYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          161 c          119 g          110 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tggcctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcacgggcac
      181 cagcagttac atcggtggtt acaactttgt ctcctggtac caacaccatc cagacacagc
      241 ccccaaactc gtgatttatg aggtcactca gcggccctca ggggtctctg atcggttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgaatat tactgcagtt catatgcaga catctacaca tttgtgttcg gaagtggcac
      421 caagttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001135             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:26683:10866
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001135
VERSION     KCVO01001135.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:26683:10866"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73164.1"
                     /translation="DYYCYSSDSSADYWVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           91 a          141 c          127 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggtt ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaaactg actactactg
      361 ttactcatca gatagcagtg ctgattattg ggtgttcggc ggagggaccc ggctgaccgt
      421 cccaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001136             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:11519:10763
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001136
VERSION     KCVO01001136.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11519:10763"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73165.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          146 c          136 g           99 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctct gacctcactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag attcacctgt gggggaggca
      181 atgttggaag tgaatatgtc cactggtatc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatctctta taatactgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt ttgggacagt aggagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001137             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:11780:11356
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001137
VERSION     KCVO01001137.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:11780:11356"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73166.1"
                     /translation="DYHCFSTDSSGNHRGIF"
     J_segment       396..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          146 c          126 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgacgac agcaaacggc cctctgggat ccctgcgaga gtctctggct ccagctcagg
      301 gacagtggcc accttgacta tcattggggc ccaggtggag gatgaagctg actaccactg
      361 tttctcaaca gatagcagtg gtaatcatag gggcatattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001138             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:8267:14862
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001138
VERSION     KCVO01001138.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8267:14862"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..434
                     /note="immunoglobulin light chain variable region"
     V_region        107..434
     V_segment       107..402
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73167.1"
                     /translation="DYYCSSYVVGNTLF"
     J_segment       403..434
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          154 c          121 g          112 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcaggac gtctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaat
      181 cagcaatgac atcggtggtt ataactatgt ctcctggtac cagcagcacc caggcaaagc
      241 ccccaaattc atgatttttg atgtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaaa tctggcaaca cggcctccct gaccatctct ggcctccagg ctgaggatga
      361 ggctgattat tactgcagct catatgttgt aggcaacact ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001139             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:24272:10285
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001139
VERSION     KCVO01001139.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24272:10285"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73168.1"
                     /translation="DYYCFSTENSVNHRVLF"
     J_segment       380..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           95 a          139 c          115 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggat ccagcagaag ccaggccagt cccctgttct gatcatctat gaagacagga
      241 aacggccctc tgggatctct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgtttc tcaacagaaa
      361 acagtgttaa tcatagggtc ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001140             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:23735:17243
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001140
VERSION     KCVO01001140.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:23735:17243"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73169.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       397..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          142 c          140 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagactctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaaacc agcgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctgg gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgtgtatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001141             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:17680:12516
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001141
VERSION     KCVO01001141.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:17680:12516"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..430
                     /note="immunoglobulin light chain variable region"
     V_region        107..430
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73170.1"
                     /translation="DYFCCSYTDTYTFVF"
     J_segment       407..430
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>475
                     /gene="IGLC"
BASE COUNT           84 a          157 c          121 g          113 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactttgt ctcctggtac caacaacatc caggcacagc
      241 ccccaaactc atgatttatg aggtcaatca gcggccctca ggggtctctg atcgcttctc
      301 tggctcaaag tctggcaaca cggcctccct gaccgtctcc ggggtccagg ctgaggacga
      361 ggctgattat ttctgctgct catatacaga cacctacact tttgttttcg gaagtggcac
      421 caggttgacc gtcgtcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001142             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:17900:11730
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001142
VERSION     KCVO01001142.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17900:11730"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    129..453
                     /note="immunoglobulin light chain variable region"
     V_region        129..453
     V_segment       129..416
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73171.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       417..453
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT          100 a          151 c          134 g          106 t
ORIGIN      
        1 acatggggag agaagcctag ggagcccagc tgtgctgtgg gctcaggagg cagagctctg
       61 ggtgtctcac catggcctgg attcctctcc tactccccct cctcactttc tgcacaggct
      121 ctgcagcctc ctctgagctg acacagccac cctcggtgtc agtgtcccca ggacagacgg
      181 ccaggatcac ctgctctgga gatgcattgt caaaatacta tgcttattgg ttccagcaga
      241 agccaggcca gtcccctgtg gcgatcatct atgaggacaa caaacggccc tctgggatcc
      301 ctgagagatt ctctggctcc agctcaggga cagtggccac cttgactatc agtggggccc
      361 aggtcgagga tgaagctgac tactactgtt actcaacaga tagcagtggt actaatggct
      421 tattcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      481 ctctcttccc g
//
LOCUS       KCVO01001143             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:20521:16007
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001143
VERSION     KCVO01001143.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20521:16007"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73172.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           86 a          154 c          123 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat atacaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001144             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:6937:17443
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001144
VERSION     KCVO01001144.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:6937:17443"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <347..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73173.1"
                     /translation="ADYYCSTDSSGNYVF"
     J_segment       386..419
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT           91 a          140 c          126 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcaacagat agtagtggta attatgtatt cggcggaggg acccggctga ccgtcctagg
      421 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001145             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:11651:16473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001145
VERSION     KCVO01001145.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:11651:16473"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73174.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           83 a          158 c          120 g          114 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtactt ataactatgt ctcctggtac caacaacatc caggcacagc
      241 ccccaaactc atgatttttg aggtcagtga gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgttgct catatgcaga cacctacact tttgtgtttg gaggtggcac
      421 cagcttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001146             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:19505:11012
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001146
VERSION     KCVO01001146.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19505:11012"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73175.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       400..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           89 a          146 c          135 g           98 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acaggctctg cggtctccta tgagctgact
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 aaccttggag ataaatatct acactggtat caccagaagc cagcgcaggc ccctgtgctg
      241 gtcatctact atgatagtga ccggccctca tggatccctg agcgattctc tgggtccaag
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag taataatgat catatctttt tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001147             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:14301:13358
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001147
VERSION     KCVO01001147.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14301:13358"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73176.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       396..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           90 a          142 c          138 g           96 t
ORIGIN      
        1 acatgggagc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg cttactgcac agactctgcg gtctcctatg acctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 tgttggaagt gaatatgtgc actggtacca acagaaacca gcgcaggccc ctgtggtggt
      241 catccattat aatagtgacc ggccctcagg gatccctgag cgattctctg gctccaaatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta gtagtgatca ttgtgtattg ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001148             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:24194:10628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001148
VERSION     KCVO01001148.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:24194:10628"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73177.1"
                     /translation="DYYCAAWDDSLNSPFF"
     J_segment       414..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           93 a          161 c          119 g          109 t
ORIGIN      
        1 acatggggca ccttcagctg cgggtacaga aggcaggact caggataatc tccagcatgg
       61 cctggttccc tctcgtcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gccaccctca acgtctgggg ctcccgggca gagtgtcacc atctcttgct
      181 ctggaagcag ctccaacatt ggaagtaatt atgtaaactg gtaccagcaa ctcccaggaa
      241 cggcccccaa actcctcatc tattttacta atcagcgacc ctcaggggtc cctgaccgat
      301 tctctggctc taagtctggc acctcagcct ccctggccat cactggtctc cgatctgagg
      361 atgaggctga ttattactgt gcggcatggg atgacagcct gaacagtccc ttcttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001149             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:6222:13128
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001149
VERSION     KCVO01001149.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:6222:13128"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73178.1"
                     /translation="DYHCHSTESSGNRPVF"
     J_segment       391..425
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          144 c          123 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttttt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actaccactg
      361 tcactcaaca gagagcagtg gtaatcgtcc tgtgttcgga agtggcacca agttgaccgt
      421 cctcggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01001150             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:16655:3952
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001150
VERSION     KCVO01001150.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:16655:3952"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73179.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       402..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           87 a          156 c          123 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtaa tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacacaag cagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001151             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:13417:9419
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001151
VERSION     KCVO01001151.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:13417:9419"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73180.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       411..446
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           89 a          157 c          130 g          108 t
ORIGIN      
        1 acatggggct ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct cctctcctcc tcacccttct cattcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagtgtctgg ggaccccggg cagagggtca ccatctcgtg
      181 cactgggagc agctccaaca ttggaggtta ttttgtgtac tggtaccagc agttcccagg
      241 aacagccccc aaactcctca tctatgacaa taataagcga ccctcaggga tttctgaccg
      301 attctctggc tccaagtctg gtacctcagc ctccctgacc atcactgggc tccagcctgg
      361 ggatgaggct gattattact gcggagcatg ggatagcagc ctgagtgctc gcttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCVO01001152             506 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:23760:13446
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001152
VERSION     KCVO01001152.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 506)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 506)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..506
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:23760:13446"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    138..467
                     /note="immunoglobulin light chain variable region"
     V_region        138..467
     V_segment       138..431
                     /gene="IGLV8-111"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <396..>440
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73181.1"
                     /translation="DYYCTLYLGSAIYIF"
     J_segment       432..467
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        468..>506
                     /gene="IGLC"
BASE COUNT          103 a          165 c          126 g          112 t
ORIGIN      
        1 acatggggga aaaggccctg aggaaaacaa actccagctg agaagcctga gagcacttgg
       61 ccttcataag tgtccccacc atggcctgga tgatgcttct cctcggactc cttgcttatg
      121 gctcaggagt ggattctgag actgtggtga cccaggagcc atcgttgtca gtgtcccctg
      181 gaggaacagt cacactcacc tgtggcctga gctctggctc agtctctacc agcaactacc
      241 ccagctggtt ccagcagacc ccaggccagg ctccacgcat cctcatccac agcacacaca
      301 gtcgcccttc tggggtccct gatcgcttca ctggctccat ccttgggaac aaagctgccc
      361 tcaccatcac gggggctcag gcagacgatg agtctgatta ttactgtacg ctgtacttgg
      421 gtagtgccat ttacatcttc ggtcctggga cccggctcac cgtcctaagt cagcccaagg
      481 cttcccccac ggtcactctg ttcccg
//
LOCUS       KCVO01001153             494 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:10298:17707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001153
VERSION     KCVO01001153.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 494)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:10298:17707"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..456
                     /note="immunoglobulin light chain variable region"
     V_region        123..456
     V_segment       123..416
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73182.1"
                     /translation="DYYCLSYDSSLRAHYIF"
     J_segment       419..456
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>494
                     /gene="IGLC"
BASE COUNT           96 a          166 c          124 g          108 t
ORIGIN      
        1 acatgggggg ggaagctctg cttcagctgt gggcacagga ggcagcactc aggacagtct
       61 ccagcatggc ctcgtctcct ctcctcctca cccttctcat tcactgcaca gggtcctggg
      121 cccagtctgt gctgacacag ccaccctcag tgtctggggc cccagggcag agggtcacca
      181 tctcgtgcac tgggagcagc tccagcgttg gaggtgatta tgtatcctgg taccaacagc
      241 tcccaggaac gacccccaaa ctcctcatct atcaaaataa taagcgaccc tcaggggttt
      301 ctgaccgatt ctctggctcc aagtctggta cctcagcctc cctgaccatc actgggctcc
      361 agactgagga tgaggctgat tactactgcc tgtcctatga cagcagcctg agagctcatt
      421 acatcttcgg tcctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg
      481 tcactctgtt cccg
//
LOCUS       KCVO01001154             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:24587:14226
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001154
VERSION     KCVO01001154.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:24587:14226"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..269
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73183.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       276..306
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           73 a           99 c          101 g           71 t
ORIGIN      
        1 acatgggggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaacc
       61 ttggagataa atatctacac tggtacctcc agaagccagc gcaggcccct gtgctggtca
      121 tctactatga tagtgaccgg ccctcatgga tccctgagcg attctctggg tccaagtcag
      181 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      241 gtcaggtgtg ggacagtaat aatgatcata tctttttcgg aggagggacc cggctgaccg
      301 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001155             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:22327:15689
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001155
VERSION     KCVO01001155.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:22327:15689"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..438
                     /note="immunoglobulin light chain variable region"
     V_region        117..438
     V_segment       117..401
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73184.1"
                     /translation="DYYCYSTDTSGHGLF"
     J_segment       402..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           94 a          145 c          128 g          109 t
ORIGIN      
        1 acatgggggg agcccagctg tgctgtgggc tcaggaggca gagctctggg tgtctcacca
       61 tggcctggat tcctctccta ctccccctcc tcactttctg cacaggctct gcagcctcct
      121 atgagctgac acagccaccc tcggtgtcag tgtccccagg acagacggcc aggatcacct
      181 gctctggaga tgcattgcca aaaaaatatg tttattggtt ccagcagaag ccaggccagt
      241 cccctgtact gatcatctat gaggacttta aacggccctc tgggatccct gagagattct
      301 ctggctccag ctcagggaca gtggccacct tgactttcag tggggcccag gtggaggatg
      361 aagctgacta ctactgttac tcaacagata ctagtggtca tggcctattt ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001156             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:13347:3847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001156
VERSION     KCVO01001156.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13347:3847"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV10-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73185.1"
                     /translation="DYYCSAWDSSLSAVLF"
     J_segment       398..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT          107 a          158 c          123 g           84 t
ORIGIN      
        1 acatggggaa agcagagctt cggcaagcac agtgggaatc cgcaccatgc cctgggctct
       61 gctcctcctg accctcctca ctcactctgc agtgccagtg gtccaggcag ggctgactca
      121 gccaccctca gtgtccaagg gcttgagaca gacggccaca ctcacctgca ctggaaacag
      181 caacaatttt ggcaaccagg gagcaggttg gctgcagcag caccagggcc accctcccaa
      241 actgctgtcc tacaggaata acaaccggcc ctcgggaatc tcagagagat tctctgcatc
      301 caggtcagga aacacagcct ccctgaccat caccggactc caacctgagg atgaggctga
      361 ctattactgc tcagcatggg acagcagcct cagtgctgtg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001157             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:23405:8202
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001157
VERSION     KCVO01001157.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:23405:8202"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..454
                     /note="immunoglobulin light chain variable region"
     V_region        130..454
     V_segment       130..416
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73186.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       422..454
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT          107 a          144 c          134 g          107 t
ORIGIN      
        1 acatggggaa gagaagccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactccccc tcctcacttt ctgcacaggc
      121 tctgcagcct cctatgagct gacacagcca ccctcggtgt cagtgtcccc aggacagacg
      181 gccaggatca cctgctctgg agatgcattg ccaaaaaaat atgtatattg gttccagcag
      241 aagccaggcc agtcccctgt gttgatcatc tatgaggaca acaaacggcc ctctgggatt
      301 cctgagagat tctctggctc cagctcaggg acagtggcca ccttgactat cagtggggcc
      361 caggtggagg atgaaggtga ctactactgt tactcaagag atagtagtga aaatcaaagc
      421 gtcttcggtg ctgggacccg gctcagcgtc ctaggtcagc ccaaggcttc ccccacggtc
      481 actctgttcc cg
//
LOCUS       KCVO01001158             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:8507:21709
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001158
VERSION     KCVO01001158.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8507:21709"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73187.1"
                     /translation="DYYCQVWDSNSDHIIF"
     J_segment       394..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          143 c          137 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgag ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaacc
      181 ttggagatga gtatttacac tggtaccagc agaagccagc gcgggcccct gtgctggtca
      241 tctactatga tagtgaccgg ccctcatgga tccctgagcg attctctggg tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtaat agtgatcata ttatattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001159             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:12110:12276
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001159
VERSION     KCVO01001159.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12110:12276"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73188.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           82 a          157 c          126 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtggtt ataaccgtgt ctcctggttc caacagcacc caggcaaagc
      241 ccccaaactc atgatttgtg acgtcagtga tcggccctca ggggtctctg ctcgcttctc
      301 tggttccaag tctggcaata cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacgcaag cagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001160             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:16285:18338
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001160
VERSION     KCVO01001160.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:16285:18338"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73189.1"
                     /translation="DYYCQVWDSSSDVFF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          140 c          139 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 aggcacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcattggaag tagaagtgta cagtggtacc agcagaaggc accgcaggcc cttatactgg
      241 tcatctatgc tgataacgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttcttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001161             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:10353:10745
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001161
VERSION     KCVO01001161.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10353:10745"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73190.1"
                     /translation="DYYCYATDSSGYRGLF"
     J_segment       389..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          140 c          132 g          102 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggggatgcat
      181 tgccgaaaaa ttatgcttat tggttccggc agaagccagg ccagtcccct gtgatgatca
      241 tctatgagga cagcaaacgg ccgtctggga tccctgagag attctctggc tccagctcag
      301 ggacagtggc caccttgact atcagtgggg cccaggtgga ggatgaagct gactactact
      361 gttacgcaac agatagcagt ggttatcgtg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001162             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:13880:13261
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001162
VERSION     KCVO01001162.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13880:13261"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73191.1"
                     /translation="DYYCAAWDDSLSSPLF"
     J_segment       393..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          148 c          117 g          110 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagtcaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagtttcaac
      181 attggaagta attatgtaaa ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 atctatttta gtaatcagcg gccctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcat gggatgatag tctgagcagt cccttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001163             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:28780:15021
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001163
VERSION     KCVO01001163.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:28780:15021"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73192.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           98 a          143 c          121 g           98 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagtc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggtaccagca gaaaccaggc cagtccccta tgctgatcat
      241 ctatgaggac aacaaacggc cctctgggat ccctgaaaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacaacagtg gtcagggctc attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001164             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:18540:10861
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001164
VERSION     KCVO01001164.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:18540:10861"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73193.1"
                     /translation="DYYCQMWDITTDHDVF"
     J_segment       389..425
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           95 a          137 c          128 g          103 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatgacct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ttctgcggcc tcctatgagc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaaa aatgtccact ggtaccagca gaagccaccg caggcccctg tattggtcat
      241 ctattatgat atcgaacggc cctcagggat ccctgagcga ttctctggcg ccaaatcagg
      301 gaacaccgcc accctgatca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcagatgtgg gacattacta ctgatcatga tgtgtttgga agtggcacca agttgaccgt
      421 cctcggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01001165             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:5020:17703
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001165
VERSION     KCVO01001165.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:5020:17703"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73194.1"
                     /translation="DYYCSSYTSSITWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           88 a          155 c          119 g          110 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg cctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtaatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aagacgaggc
      361 tgattattac tgcagctcat acacaagtag tatcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001166             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:12523:8514
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001166
VERSION     KCVO01001166.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12523:8514"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..448
                     /note="immunoglobulin light chain variable region"
     V_region        119..448
     V_segment       119..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73195.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       413..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>487
                     /gene="IGLC"
BASE COUNT           91 a          157 c          128 g          111 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagtcgc cctcagtgtc tggggcgccc gggcagaggg tcaccatctc
      181 ctgcactggg ggcagctcca acattggaga ctattatgtg cagtggtacc agcagcttcc
      241 aggaacggcc cccaaatttc tcatctatga aaataataag cgaccctcag gggtttctga
      301 tcgattctct ggctcccagt ctggtacctc agcctccctg accatcactg gactccagtc
      361 tgaggatgag gctgattatt actgccagtc ctatgacagc agcctgagtg ccgtgttatt
      421 cggaggaggg acccggctga ccgtcctacg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCVO01001167             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:13756:8378
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001167
VERSION     KCVO01001167.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13756:8378"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73196.1"
                     /translation="DYYCAAWDDSLSSPFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          154 c          117 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaac
      181 attggaagta attatgtaaa ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 atctatttta gtaatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcggcat gggatgacag cctgagcagt cccttcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001168             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:16178:11684
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001168
VERSION     KCVO01001168.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16178:11684"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    131..455
                     /note="immunoglobulin light chain variable region"
     V_region        131..455
     V_segment       131..417
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73197.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       423..455
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT          107 a          143 c          135 g          108 t
ORIGIN      
        1 acatggggga agagaagcct agggagccca gctgtgctgt gggctcagga ggcagagctc
       61 tgggtgtctc accatggcct ggattcctct cctactcccc ctcctcactt tctgcacagg
      121 ctctgcagcc tcctatgagc tgacacagcc accctcggtg tcagtgtccc caggacagac
      181 ggccaggatc acctgctctg gagatgcatt gccaaaaaaa tatgtatatt ggttccagca
      241 gaagccaggc cagtcccctg tgttgatcat ctatgaggac aacaaacggc cctctgggat
      301 tcctgagaga ttctctggct ccagctcagg gacagtggcc accttgacta tcagtggggc
      361 ccaggtggag gatgaaggtg actactactg ttactcaaga gatagtagtg aaaatcaaag
      421 tgtcttcggt gctgggaccc ggctcagcgt cctaggtcag cccaaggctt cccccacggt
      481 cactctgttc ccg
//
LOCUS       KCVO01001169             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:12673:16732
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001169
VERSION     KCVO01001169.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12673:16732"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73198.1"
                     /translation="DYYCHSTDSSRNHLF"
     J_segment       392..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           96 a          143 c          122 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgaatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac aacaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 tcactcaaca gatagcagtc gtaatcactt gttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001170             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:17280:17022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001170
VERSION     KCVO01001170.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17280:17022"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..447
                     /note="immunoglobulin light chain variable region"
     V_region        118..447
     V_segment       118..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73199.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       412..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>486
                     /gene="IGLC"
BASE COUNT           91 a          156 c          129 g          110 t
ORIGIN      
        1 acatgggggg ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggaggt tattatgtgc agtggtacca gcaacttcca
      241 ggaacggccc ccaaagttct catctatgaa aataataagc gaccctcagg ggtttctgat
      301 cgattctctg gctcccagtc tggtacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gcctgagtgc cgtgttattc
      421 ggaggaggga cccggctgac cgtcctaagt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01001171             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:22339:6671
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001171
VERSION     KCVO01001171.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:22339:6671"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..433
                     /note="immunoglobulin light chain variable region"
     V_region        106..433
     V_segment       106..398
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73200.1"
                     /translation="DYYCFVYYSGTQFF"
     J_segment       403..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           99 a          154 c          117 g          101 t
ORIGIN      
        1 acatgggggg ctctggagcc agagatccct tccaatacca gcaccatggc ctggactctg
       61 ctcctcctcc agttcctcct cacttgctgc ccagggtcca attctcaggc tgtagtgact
      121 caggagccct caatgactgt gtccccagga gggacagtca ctctcacctg tggctccagc
      181 actggagcag tcaccagtgg taactttcca aactggttcc agcagaaacc tggacaagtc
      241 cccaggggac tgatttacaa tacaaacaac aaacactcct ggacccctgc ccggttctca
      301 ggctccctcg ctgggggcaa agctgccctg acactgtcag gagcacagcc cgaggacgag
      361 gctgattatt actgcttcgt gtactatagt ggtactcaat tcttcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggttgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001172             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:22022:9392
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001172
VERSION     KCVO01001172.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:22022:9392"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73201.1"
                     /translation="DYYCCSYAGRFTFVF"
     J_segment       407..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           80 a          158 c          124 g          113 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactgggac
      181 cagcagtgac atcggtggtt atgactttgt ctcctggtac caacagcttc caggcacagc
      241 ccccaaactc atgatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tccggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 cgctgattat tactgctgct catatgcagg caggttcact tttgtattcg gaagtggcac
      421 caagttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001173             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:18253:14319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001173
VERSION     KCVO01001173.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:18253:14319"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73202.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       397..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          143 c          140 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggcagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagtctctgt ggtctcccat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaagcc agcgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgtgtatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001174             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:19778:6433
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001174
VERSION     KCVO01001174.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19778:6433"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..402
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73203.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       403..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           85 a          161 c          122 g          108 t
ORIGIN      
        1 acatgggggg ctgggatctc aggaggcagc actctcagga cgtctccacc atggcctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccctga
      121 ctcagtctcc ctctgtgtct gggtctcctg gacagtcggt caccatttcc tgcactggaa
      181 ccagcagtga cattggtggt tataaccgtg tctcctggta ccaacagcac ccaggcaaag
      241 cccccaaact catgatttat gacgtcagtg atcggccctc aggggtctct gatcgcttct
      301 ctggttccaa gtctggcaac acggcctccc tgatcatctc tgggctccag gctgaggacg
      361 aggctgatta ttactgcagc tcatacgcaa gcactaccac ttggctattc ggcggaggga
      421 cccgcctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001175             500 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:24536:9644
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001175
VERSION     KCVO01001175.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 500)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 500)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:24536:9644"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    132..462
                     /note="immunoglobulin light chain variable region"
     V_region        132..462
     V_segment       132..424
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <387..>434
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73204.1"
                     /translation="EYYCQSYDSSLSAVLF"
     J_segment       426..462
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        463..>500
                     /gene="IGLC"
BASE COUNT           94 a          150 c          140 g          116 t
ORIGIN      
        1 acatggggag gtgactggat acaggtccag gggaggggcc ctgggaagcc tattgatgat
       61 tggtttctcc tcttgtctct agaaccagag tcatgatgcc tgtgtctctc ccacttccag
      121 ggtcctgggc ccagtctgtg ctgacgcagc cgccctcagt gtctggggcg cccggacaga
      181 gggtcaccat ctcctgctct gggagcagct ccaacattgg aggttattat gtccagtggt
      241 accagcagct tccaggaacg gcccccaaag tcctcatcta tgaaaatagt aagcgaccct
      301 caggggtttc tgatcgattc tctggctccc agtctggaac ctcagcctcc ctgaccatca
      361 ctggactcca gtctgaggat gaggctgagt attactgcca gtcctatgac agcagcctga
      421 gtgccgtgtt attcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc
      481 cctcggtcac tctcttcccg
//
LOCUS       KCVO01001176             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:15707:7141
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001176
VERSION     KCVO01001176.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:15707:7141"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73205.1"
                     /translation="DYYCQVYDGSAWVF"
     J_segment       408..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          158 c          126 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ctgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agaaatgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctcta ctacttctcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacg tcaagtaatg cagcgttttt gatcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacgg tagtgcttgg gtattcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001177             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:15680:15706
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001177
VERSION     KCVO01001177.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15680:15706"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73206.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           82 a          157 c          121 g          115 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtactt ataactatgt ctcctggtac caacagcatc caggcacagc
      241 ccccaaactc atgatttttg aggtcagtga gcggccctca ggggtctctg gtcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct ggtctccagg ctgaggacga
      361 ggctgattat tactgttgct catatgcaga cacctacact tttgtgtttg gaggtggcac
      421 cagattgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001178             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:19749:9979
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001178
VERSION     KCVO01001178.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:19749:9979"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..265
                     /note="immunoglobulin light chain variable region"
     V_region        8..265
     V_segment       8..223
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>237
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73207.1"
                     /translation="DYFCSVWDSSLTIYIF"
     J_segment       228..265
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        266..>303
                     /gene="IGLC"
BASE COUNT           61 a           94 c           70 g           78 t
ORIGIN      
        1 acatggggct ccaacatcgg ggcgggttat tctgtatcct ggtatcagca gttcccagga
       61 acagccccca aactcctcat ctatgaaaat aataagcgac cctcaggggt ttctgaccga
      121 ttctctggct ccaagtctgg tacctcagcc tccctgacta tcactggact ccaatctgag
      181 gatgaggctg attatttctg ctctgtctgg gatagcagcc tgactattta catcttcggt
      241 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      301 ccg
//
LOCUS       KCVO01001179             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:20875:20281
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001179
VERSION     KCVO01001179.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20875:20281"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73208.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          160 c          120 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001180             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:22658:13095
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001180
VERSION     KCVO01001180.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:22658:13095"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73209.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       402..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           87 a          154 c          124 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagtacc caggcaaagc
      241 ccccaaagtc atcatttatg aggtcagtga tcggccctca ggggtctctg atcgcttcac
      301 tggtttcaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacacaag cagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001181             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:20509:11502
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001181
VERSION     KCVO01001181.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20509:11502"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73210.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       392..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           91 a          143 c          127 g          103 t
ORIGIN      
        1 acatggggtg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccaaaaaa gtatgcttat tggttccagc agaagccagg ccagtcccct gtgctgatca
      241 tctatgagga cagcagacgg ccctctggga tccctgagag attctctggc tccagctcag
      301 ggacagtggc caccttgact atcagtgggg cccaggggga ggatgaagct gactactact
      361 gttattcaat ggatagcagt ggtactcaga gcatcttcgg tgctgggacc cggctcaccg
      421 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCVO01001182             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:21474:18025
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001182
VERSION     KCVO01001182.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:21474:18025"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73211.1"
                     /translation="DYYCQSYDTRLRAWVF"
     J_segment       412..448
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           94 a          158 c          127 g          107 t
ORIGIN      
        1 acaggggaag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcagtcact gcacagggtc ctgggcccag
      121 tctgtcctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggagat tattttgtgc agtggtacca acagcttcca
      241 ggaacggccc ccaaactcct catctatgaa aatgataaac ggccctcagg agtttctgat
      301 cgattctctg gctcccagtc tggaacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgaga ctgattatta ctgccagtcc tatgacacca gattgagggc ttgggtattc
      421 ggcggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01001183             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:20284:13252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001183
VERSION     KCVO01001183.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:20284:13252"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..422
                     /note="immunoglobulin light chain variable region"
     V_region        104..422
     V_segment       104..385
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73212.1"
                     /translation="DYYCQSTDSSGFIF"
     J_segment       388..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT          101 a          136 c          119 g          104 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgtg gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actgacaaaa aattatgctc agtggttcca gcagaagcca ggccaggccc ctgtgctgct
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca gttaccttga ccatcagtcg ggcccaggta gaagatgagg ctgactatta
      361 ttgtcaatca acagacagca gtggtttcat cttcggtgct gggacccggc tcaccgtcct
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01001184             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:24414:12612
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001184
VERSION     KCVO01001184.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:24414:12612"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73213.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       391..421
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           90 a          144 c          126 g           99 t
ORIGIN      
        1 acatgggggg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactccccc tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agatgcattg
      181 ccagaaaaat atgcttattg gttccagcag aagccaggcc agtcccctgt gctgatcatc
      241 aatgaggaca gcaaacggcc ctctgggatc cctgggagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactct cagtggggcc caggtggagg atgaagctga ctactactgt
      361 tcctcaacag acagtagtgg taattatgtc ttcggcggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001185             572 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:19073:5870
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001185
VERSION     KCVO01001185.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 572)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 572)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..572
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19073:5870"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    204..534
                     /note="immunoglobulin light chain variable region"
     V_region        204..534
     V_segment       204..495
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <459..>506
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73214.1"
                     /translation="DYYCGAWDSSLSGRLF"
     J_segment       499..534
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        535..>572
                     /gene="IGLC"
BASE COUNT          111 a          171 c          165 g          125 t
ORIGIN      
        1 acatgggggg ggattagaaa gctgggggcc tgatttgcat ggatggaccc tcccactctc
       61 agagtatgaa gaggggcagg gagagatttg gggaagctct gcttcagctg tgggcacagg
      121 aggcagcact caggacagtc tccagcatgg cctggtctcc tctcctcctc acccttctca
      181 ttcactgcac agggtcctgg gcccagtctg tgctgacgca gccgccctca gtgtctgggg
      241 accccgggca gagggtcacc atctcgtgca ctgggagcag ctccaacatt ggaggttttc
      301 ttgtatactg gtaccagcag ttcccaggaa cagcccccaa actcctcatc tatgacaata
      361 ataagcgacc ctcagggatt tctgaccgat tctctggctc caagtctggt acctcagcct
      421 ccctgaccat cactgggctc cagcctgggg atgaggctga ttattactgc ggagcatggg
      481 atagcagcct gagtggtcgc ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      541 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001186             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:9687:3260
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001186
VERSION     KCVO01001186.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9687:3260"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73215.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           85 a          155 c          123 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgtt catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001187             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:13727:18074
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001187
VERSION     KCVO01001187.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13727:18074"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73216.1"
                     /translation="DYYCQVWDSSRDHPIF"
     J_segment       390..424
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           80 a          144 c          136 g          102 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctta ctgcacagtc tctgcggtct cctatgagtt gactcagcca
      121 ccctcggtgt cagtgtcccc aggacggacg gccaggatca cgtgtggggg agacatcgtt
      181 ggaagtgaat atgttcactg gtatcagcag aagtcagcgc aggcccctgt ggtggtcatc
      241 tattattatt ctgaccggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 agcaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctactactgt
      361 caggtgtggg acagtagtcg tgatcatccc atcttcggtg ctgggacccg actcaccgtc
      421 ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01001188             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:23780:9893
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001188
VERSION     KCVO01001188.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:23780:9893"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73217.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           90 a          143 c          126 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagtagtg gtaattatgt attcggcggc gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001189             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:11319:14613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001189
VERSION     KCVO01001189.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11319:14613"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73218.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          162 c          118 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc ctttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa caccacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgt
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac ttccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001190             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:18810:12209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001190
VERSION     KCVO01001190.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:18810:12209"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73219.1"
                     /translation="DYYCSSYTSTSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           86 a          157 c          121 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa caacacccag gcaaagcccc
      241 caaactcatg atttctgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcac tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001191             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:8540:12435
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001191
VERSION     KCVO01001191.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8540:12435"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..382
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73220.1"
                     /translation="DYYCQSTDSSGYIF"
     J_segment       383..419
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT          102 a          134 c          118 g          103 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgtggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 gacaaaaaat tatgctcagt ggttccagca gaagccaggc caggcccctg tgctgctgat
      241 atataaagac agtgagaggc cctcagggat tcctgagcga ttctctagct ccagttcagg
      301 gacaacagtt accttgacca tcagtcgggc ccaggtagaa gatgaggctg actattattg
      361 tcaatcaaca gacagcagtg gttacatctt cggtgctggg acccggctca ccgtcctagg
      421 tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01001192             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:4385:16660
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001192
VERSION     KCVO01001192.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:4385:16660"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73221.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          160 c          125 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gtctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001193             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:27007:21046
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001193
VERSION     KCVO01001193.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:27007:21046"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73222.1"
                     /translation="DYYCAAWDDSLNSPFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          156 c          114 g          104 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatccctt gctctggaag cagctccaac
      181 attggaagta attatgtaaa ctggtaccag caactcccag gaacggcccc caaactcctc
      241 atctatttta ctaatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcggcat gggatgacag cctgaacagt cccttcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001194             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:19703:3538
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001194
VERSION     KCVO01001194.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19703:3538"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73223.1"
                     /translation="DYHCFSTDSSGHHRGLF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           88 a          144 c          118 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gacgacagca
      241 agcggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcat tggggcccag gtggaggatg aagctgacta ccactgtttc tcaactgata
      361 gcagtggtca tcataggggc ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001195             494 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:19113:18707
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001195
VERSION     KCVO01001195.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 494)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:19113:18707"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..456
                     /note="immunoglobulin light chain variable region"
     V_region        123..456
     V_segment       123..416
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73224.1"
                     /translation="DYYCLSYDSSLSAHYIF"
     J_segment       419..456
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>494
                     /gene="IGLC"
BASE COUNT           96 a          166 c          122 g          110 t
ORIGIN      
        1 acatgggggg ggaagctctg cttcagctgt gggcacagga ggcagcactc aggacagtct
       61 ccagcatggc ctcgtctcct ctcctcctca cccttctcat tcactgcaca gggtcctggg
      121 cccagtctgt gctgacacag ccaccctcag tgtctggggc cccagggcag agggtcacca
      181 tctcgtgcac tgggagcagc tccagcattg gaggtgatta tgtatcctgg taccaacagc
      241 tcccaggaac gacccccaaa ctcctcatct atcaaaataa taagcgaccc tcaggggttt
      301 ctgaccgatt ctctggctcc aagtctggta cctcagcctc cctgaccatc actgggctcc
      361 agactgagga tgagtctgat tactactgcc tgtcctatga cagcagcctg agtgctcatt
      421 acatcttcgg tcctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg
      481 tcactctgtt cccg
//
LOCUS       KCVO01001196             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:24114:23210
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001196
VERSION     KCVO01001196.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:24114:23210"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73225.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       391..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          144 c          127 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcagacggc cctctgggat ccctgagaga ttctctgccg ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccagggggag gatgaagctg actactactg
      361 ttattcaatg gatagcagtg gtactcagag catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001197             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:18976:11978
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001197
VERSION     KCVO01001197.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18976:11978"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73226.1"
                     /translation="DYYCSSYASSSTWIF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           88 a          156 c          122 g          107 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat aatttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacgcaagca gtagcacttg gatattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001198             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:20436:10849
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001198
VERSION     KCVO01001198.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20436:10849"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..423
                     /note="immunoglobulin light chain variable region"
     V_region        101..423
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73227.1"
                     /translation="DYYCQVWDFSGDHNIF"
     J_segment       390..423
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>463
                     /gene="IGLC"
BASE COUNT           88 a          148 c          130 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatgacct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctctgagc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccagaatc acctgtggga gagacaacat
      181 tggagataag aatgtgcact ggtaccagca gcggccaccg cgggcccctg tactggtcat
      241 ctattatgat accgaacggc cctcagggat ccctgagcga ttctctggct ccacatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gactttagtg gtgatcataa catcttcgat gctgggaccc ggctcaccgt
      421 cctcggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001199             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:21994:16708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001199
VERSION     KCVO01001199.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:21994:16708"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73228.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       405..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           84 a          160 c          120 g          109 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgac gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacgcaagca ctaccacttg gcttttcggc ggagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001200             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:5395:13133
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001200
VERSION     KCVO01001200.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:5395:13133"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73229.1"
                     /translation="DYYCQVWDSSSDVFF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          142 c          138 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattaactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcattggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttgtactgg
      241 tcatctattc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttcttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001201             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:15842:13377
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001201
VERSION     KCVO01001201.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15842:13377"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73230.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          144 c          139 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctcactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggaggca
      181 atgttggaag tgaatatgtc cactggtatc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatctgtta taatactgac cggccctcag ggatccctga ccgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt aggagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001202             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:13674:9564
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001202
VERSION     KCVO01001202.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13674:9564"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73231.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          161 c          120 g          106 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccccgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001203             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:15365:9841
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001203
VERSION     KCVO01001203.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:15365:9841"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73232.1"
                     /translation="DYYCQVWDSSSDHPIF"
     J_segment       396..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           80 a          148 c          138 g          102 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acagtctctg cggtctccta tgagctgact
      121 cagccaccct cggtgtcagt gtccccagga cggacggcca gggtcacctg tgggggagac
      181 atcgttggaa gtgaatatgt tcactggtat cagcagaagt cagcgcaggc ccctgtggtg
      241 gtcatctatt attattctga ccggccctca gggatccctg agcgattctc tggctccaaa
      301 tcagggagca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactac
      361 tactgtcagg tgtgggacag tagtagtgat catcccatct tcggtcctgg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCVO01001204             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:5329:6302
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001204
VERSION     KCVO01001204.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5329:6302"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73233.1"
                     /translation="DYYCAAWDDSLSSPFF"
     J_segment       413..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           91 a          158 c          122 g          110 t
ORIGIN      
        1 acatggggac cttcagctgc gggtacagaa ggcaggactc aggataatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag ccaccctcaa cgtctggggc tcccgggcag agtgtcacca tctcttgctc
      181 tggaagcagc tccaacattg gaagtaatta tgtaaactgg tatcagcagc tcccaggaac
      241 ggcccccaaa ctcctcatct attttagtaa tcagcgaccc tcaggggtcc ctgaccgatt
      301 ctctggctct aagtctggca cctcagcctc cctggccatc actggtctcc gatctgagga
      361 tgaggctgat tattactgtg cggcatggga tgacagcctg agcagtccct tcttcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01001205             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:17648:17063
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001205
VERSION     KCVO01001205.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17648:17063"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..388
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73234.1"
                     /translation="DYYCAAWDNSLNNVLF"
     J_segment       390..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          152 c          112 g          108 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagtgtcc tgggcccagt ctgtgctgac tcaggcaccc
      121 tcagcgtctg gggctcccgg gcagactgtc accatctctt gctctggaag cagctccaac
      181 attggaagta attatgtata ctgctaccag caattcccag gaacggcccc caaactcctc
      241 atctattata ctaatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcct gggataacag cctgaacaat gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001206             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:17186:16122
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001206
VERSION     KCVO01001206.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:17186:16122"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..424
                     /note="immunoglobulin light chain variable region"
     V_region        101..424
     V_segment       101..375
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73235.1"
                     /translation="DYYCQVRDSYSDQWVF"
     J_segment       388..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           88 a          146 c          139 g           89 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctgcacagcc tctgcggtcg cctatgagct gactcagcca
      121 cgctcagtgt ccgtgtcccc aggacagacg gccaggatca cctgtggggg agacaacatt
      181 ggaagtaaaa gtgtgcagtg gtaccaacag aagccgccgc aggcccctat actggtcatc
      241 tatgttaata gcgagcggcc ctcagggatc cctgagcgat tctctggctc caactcaggg
      301 aacaccgcca ccctgaccat tagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgcggg acagttacag tgatcaatgg gtattcggcg gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001207             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:10937:23753
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001207
VERSION     KCVO01001207.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:10937:23753"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73236.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          125 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca ccgcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001208             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:21869:11705
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001208
VERSION     KCVO01001208.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21869:11705"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..392
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73237.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       393..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           95 a          156 c          114 g          102 t
ORIGIN      
        1 acatggggac acagaaggca ggactcagga caatctccag catggcctgg ttacctctcc
       61 tcctcaccct cctcactcac tgtgcagggt cctgggccca gtctgtgctg actcagcctc
      121 cctcagcgtc tgaggccgcc aggaagagtg tcaccatctc ctgttctgga agcacctcca
      181 acatcggaac taatagtgta tcctggtacc agcagctccc agaaacggct cccaaactcc
      241 tcatctatta taatgatcga cgagcctcag gtgtctctga ccgattctct ggctccaagt
      301 ctggcacgtc agcctccctg gccatcagtg ggctccagac cgaggatgag gctgattatt
      361 actgcgcagc atgggataac agcctgagcg gttacatctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01001209             283 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:25348:12289
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001209
VERSION     KCVO01001209.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 283)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 283)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:25348:12289"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    10..245
                     /note="immunoglobulin light chain variable region"
     V_region        10..245
     V_segment       10..208
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <170..>217
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73238.1"
                     /translation="DYYCQVWDSSSKYAIF"
     J_segment       213..245
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        246..>283
                     /gene="IGLC"
BASE COUNT           59 a           88 c           82 g           54 t
ORIGIN      
        1 acatgggaga aatgtccact ggtaccagca gaagccaccg caggcccctg ttctggtcat
       61 ctatgctgat gccaaacggc cctcagggat ccctgagcga ttctctggct ccaactcagg
      121 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      181 tcaggtgtgg gacagtagta gtaaatacgc gatattcggc ggagggaccc ggctgaccgt
      241 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001210             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:22431:16654
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001210
VERSION     KCVO01001210.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:22431:16654"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73239.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           90 a          139 c          117 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatcaat gaggacagca
      241 aacggccctc tgggatccct ggaagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gtagtggtaa ttatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ttgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001211             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:10394:10591
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001211
VERSION     KCVO01001211.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:10394:10591"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..430
                     /note="immunoglobulin light chain variable region"
     V_region        104..430
     V_segment       104..396
                     /gene="IGLV10-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73240.1"
                     /translation="DYYCSAWDSSLSAVLF"
     J_segment       398..430
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>472
                     /gene="IGLC"
BASE COUNT          100 a          161 c          129 g           82 t
ORIGIN      
        1 acatggggga agccgggctt cggcaagcac agtgggaatc cgcaccatgc cctgggctct
       61 gctcctcctg accctcctca ctcactctgc agtgccagtg gtccaggcag ggctgactca
      121 gccaccctca gtgtccaagg gcttgagaca gacggccaca ctcacctgca ctggaaacag
      181 caacaatgtt ggcaaccagg gagcagcttg gctgcagcag caccagggcc accctcccaa
      241 actgctgtcc tacaggaata acaaccggcc ctcggggatc tcagagagat tctctgcatc
      301 caggtcagga aacaccgcct ccctgaccat caccggactc caacctgagg atgaggctga
      361 ctattactgc tcagcgtggg acagcagcct cagtgccgtg ttattcggag gggggacccg
      421 gctgaccgtc gtaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001212             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:19359:8770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001212
VERSION     KCVO01001212.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:19359:8770"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..425
                     /note="immunoglobulin light chain variable region"
     V_region        99..425
     V_segment       99..391
                     /gene="IGLV10-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73241.1"
                     /translation="DYYCSAWDSSLSAVVF"
     J_segment       397..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>467
                     /gene="IGLC"
BASE COUNT          102 a          157 c          126 g           82 t
ORIGIN      
        1 acatggggag agcttcggca agcacagtgg gaatccgcac catgccctgg gctctgctcc
       61 tcctgaccct cctcactcac tctgcagtgc cagtggtcca ggcagggctg actcagccac
      121 cctcagtgtc caagggcttg agacagacgg ccacactcac ctgcactgga aacagcaaca
      181 atgttggcaa ccagggagca ggttggctgc agcagcacca gggccaccct cccaaactgc
      241 tgtcctacag gaataacaac cggccctccg ggatctcaga gagattctct gcatccaggt
      301 caggaaaaac agcctccctg accatcaccg gactccaacc tgaggatgag gctgactatt
      361 actgctcagc atgggacagc agcctcagtg ccgtggtatt cggagggggg acccggctga
      421 ccgtcgttgg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001213             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:12174:8686
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001213
VERSION     KCVO01001213.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:12174:8686"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..431
                     /note="immunoglobulin light chain variable region"
     V_region        103..431
     V_segment       103..397
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73242.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       398..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>471
                     /gene="IGLC"
BASE COUNT           86 a          155 c          122 g          108 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcactct caggacgtct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 tctccctctg tgtctgggtc tcctggacag tcggtcacca tttcctgcac tggaaccagc
      181 agtgacattg gtgattataa ccgtgtctcc tggtaccaac agcacccagg caaagccccc
      241 aaactcatga tttatgaggt cagtgatcgg ccctcagggg tctctgatcg cttctctggt
      301 tccaagtctg gcaacacggc ctccctgatc atctctgggc tccaggctga ggacgaggct
      361 gattattact gcagctcata cacaagcagt agcacttggg tattcggcgg agggacccgg
      421 ctgaccgtcc ttggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001214             505 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:10905:8524
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001214
VERSION     KCVO01001214.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 505)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 505)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..505
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10905:8524"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    137..467
                     /note="immunoglobulin light chain variable region"
     V_region        137..467
     V_segment       137..430
                     /gene="IGLV8-111"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <395..>439
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73243.1"
                     /translation="DYYCAVYMGSGIDVF"
     J_segment       431..467
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        468..>505
                     /gene="IGLC"
BASE COUNT          102 a          156 c          131 g          116 t
ORIGIN      
        1 acatggggga aaggccctga ggaaaacaaa ctccagctga gaagcctgag agcacttggc
       61 cttcataagt gtccccacca tggcctggat gatgcttctc ctcggactcc ttgcttatgg
      121 ctcaggagtg gattctgaga ctgtggtgac ccaggagcca tcgttgtcag tgtcccctgg
      181 aggaacagtc acactcacct gtggcctgag ctctggctca gtctctaccg ataactaccc
      241 cagctggtac cagcagaccc caggccaggc tccacgcatg ctcctcttca acacaaacac
      301 tcgcccttct ggggtcccta ctcgcttctc tggctccatc cttgggaaca aagctgccct
      361 caccgtcacg ggggctcagg cagacgatga atctgattat tactgtgcgg tgtacatggg
      421 tagtggcatt gatgtgttcg gaagtggcac caagttgacc gtcctcggtc agcccaaggc
      481 ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001215             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:17113:9776
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001215
VERSION     KCVO01001215.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17113:9776"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73244.1"
                     /translation="DYYCSSYADTTTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          161 c          121 g          108 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtggtt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg acgtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacgcaga cactaccact tggctattcg gcggagggac
      421 ccgcctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001216             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:10539:4376
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001216
VERSION     KCVO01001216.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:10539:4376"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73245.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       409..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          156 c          129 g          108 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gtgtctgggg accccgggca gagggtcacc atctcgtgca
      181 ctgggagcag ctccaacatt ggaggttatt ttgtatactg gtaccagcag ttcccaggaa
      241 cagcccccaa actcctcatc tatgacaatt ataagcgacc ctcagggatt tctgaccgat
      301 tctctggctc caagtctggt acctcagcct ccctgaccat cactgggctc cagcctgggg
      361 atgaggctga ttattactgc ggagcatggg atagcagcct gagtgctcgc ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001217             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:15925:6964
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001217
VERSION     KCVO01001217.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:15925:6964"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..439
                     /note="immunoglobulin light chain variable region"
     V_region        109..439
     V_segment       109..403
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73246.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       404..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           79 a          154 c          122 g          122 t
ORIGIN      
        1 acatgggggg cctctgggct gattcttggt ctcctgctcc tcaggctcac ctgggcccag
       61 cactgactca ctgaagtgtg tttctccctc tttccaggat cctgggctca ggctgccctg
      121 actcagtctc cctctgtgtc tgggtctcct ggacagtcgg tcaccatttc ctgcactgga
      181 accagcagtg acattggtgg ttataaccgt gtctcctggt tccaacaaca cccaggcaaa
      241 gcccccaaac tcatgatttg tgacgtcagt aatcggccct caggggtctc tgctcgcttc
      301 tctggttcca agtctggcaa tacggcctcc ctgatcatct ctgggctcca ggctgaggac
      361 gaggctgatt attattgcag ctcatacgca agcagtagca cttgggtttt cggcggaggg
      421 acccgcctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001218             502 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:16086:12219
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001218
VERSION     KCVO01001218.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 502)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 502)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..502
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16086:12219"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..464
                     /note="immunoglobulin light chain variable region"
     V_region        119..464
     V_segment       119..425
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <395..>436
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73247.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       428..464
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        465..>502
                     /gene="IGLC"
BASE COUNT           95 a          165 c          131 g          111 t
ORIGIN      
        1 acatgggatc aacgcagagt acatgggggg gtctgtggcc tcagaggtag ccgtgtccac
       61 catggccctg actcctctcc tcctcctgct cctctctcac tgcacaggtt ccctctccca
      121 gcctgtgctg actcagccac cctccctgtc tgcatccccg ggagcatcgg ccagactccc
      181 ctgcaccctg agcagtgacc tcagtgttgg tagtaaaaac atgtactggt accagcagaa
      241 gccagggagc gctcccaggt tattcctgta ctactactcc gactcagaca agcagctggg
      301 acctggggtc cccaatcgag tctctggctc caaggagacc tcaagtaaca cagcgttttt
      361 gctcatctct gggctccagc ctgaggacga ggccgattat tactgtcagg tgtatgacag
      421 tactggagtg ttgttcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc
      481 cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001219             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:13525:20051
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001219
VERSION     KCVO01001219.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13525:20051"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73248.1"
                     /translation="DYYCGAWDSSLSTRLF"
     J_segment       407..442
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           91 a          155 c          128 g          106 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggac cccgggcaga gggtcaccat ctcgtgcact
      181 gggagcagct ccaacattgg aggttatttt gtatactggt accagcagtt cccaggaaca
      241 gcccccaaac tcctcatcta tgacaataat aagcgaccct cagggatttc tgaccgattc
      301 tctggctcca agtctggtac ctcagcctcc ctgaccatca ctgggctcca gcctggggat
      361 gaggctgatt attactgcgg agcatgggat agcagcctga gtactcgctt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001220             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:18718:17357
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001220
VERSION     KCVO01001220.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18718:17357"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73249.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       393..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           99 a          137 c          124 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgtatatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac aacaaacggc cctctgggat tcctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaaggtg actactactg
      361 ttactcaaga gatagtagtg aaaatcaaag cgtcttcggt gctgggaccc ggctcagcgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001221             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:13338:17190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001221
VERSION     KCVO01001221.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13338:17190"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73250.1"
                     /translation="DYYCGAWDSGLSARLF"
     J_segment       409..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          155 c          130 g          108 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gtgtctgggg accccgggca gagggtcacc atctcgtgca
      181 ctgggagcag ctccaacatt ggaggttatt ttgtatactg gtatcagcag ttcccaggaa
      241 cagcccccaa actcctcatc tatgacaata ataagcgacc ctcagggatt tctgaccgat
      301 tctctggctc caagtctggt acctcagcct ccctgaccat cactgggctc cagcctgggg
      361 atgaggctga ttattactgc ggagcatggg atagcggcct gagtgctcgc ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001222             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:9496:7692
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001222
VERSION     KCVO01001222.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9496:7692"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..412
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73251.1"
                     /translation="DYYCSSYASSSTWIF"
     J_segment       413..448
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           92 a          158 c          128 g          108 t
ORIGIN      
        1 acatggggca gagtacatgg gggggatctc aggaggcagc actctcagga cgtctccacc
       61 atggcctggg ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag
      121 gctgccctga ctcagtctcc ctctgtgtct gggtctcctg gacagtcggt caccatttcc
      181 tgcactggaa ccagcagtga cattggtgat tataaccgtg tctcctggta ccaacagcac
      241 ccaggcaaag cccccaaact cataatttat gaggtcagtg atcggccctc aggggtctct
      301 gatcgcttct ctggctccaa gtctggcaac acggcctccc tgatcatctc tgggctccag
      361 gctgaggacg aggctgatta ttactgcagc tcatacgcaa gcagtagcac ttggatattc
      421 ggcggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01001223             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:18892:12523
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001223
VERSION     KCVO01001223.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18892:12523"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73252.1"
                     /translation="DYYCYSSDSGADYWVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>449
                     /gene="IGLC"
BASE COUNT           87 a          138 c          121 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggttccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttat tcatcagata
      361 gcggtgctga ttattgggtg ttcggcggag ggacccggct gaccgtccca ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001224             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:21121:8773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001224
VERSION     KCVO01001224.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21121:8773"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73253.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          143 c          140 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gtgggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga acgattctct ggctccaaat
      301 cagggggcgc cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001225             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:19656:16087
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001225
VERSION     KCVO01001225.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19656:16087"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73254.1"
                     /translation="DYYCYSIDISGNHRVF"
     J_segment       376..411
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           90 a          140 c          117 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct acgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaggacagca
      241 aacggccctc tgggttccct gagcgattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaatagata
      361 tcagtggtaa tcatagggtt ttcggcggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001226             370 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:25501:7864
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001226
VERSION     KCVO01001226.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 370)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 370)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:25501:7864"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..332
                     /note="immunoglobulin light chain variable region"
     V_region        8..332
     V_segment       8..294
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <257..>304
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73255.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       296..332
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        333..>370
                     /gene="IGLC"
BASE COUNT           74 a          113 c           98 g           85 t
ORIGIN      
        1 acatggggtg ctgacgcagc cgccctcaat gtctggggcg cccgggcagg gggtcaccat
       61 ctcctgcact gggagcagct ccaatattgg agattattat gtgcagtggt accaacagtt
      121 tccaggaacg gcccccagac tcctcatcta tgaaaataat aaacgaccct caggggtttc
      181 tgatcgattc tctggctccc agtctggtac ctcagcctcc ctgaccatca ctggactcca
      241 gtctgaggat gaggctgatt attattgcca gtcctatgac agcagcctga gtgccgtgtt
      301 attcggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac
      361 tctcttcccg
//
LOCUS       KCVO01001227             436 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:21021:14158
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001227
VERSION     KCVO01001227.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 436)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 436)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:21021:14158"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    74..398
                     /note="immunoglobulin light chain variable region"
     V_region        74..398
     V_segment       74..361
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <323..>370
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73256.1"
                     /translation="DYYCQVWDSITDHSIF"
     J_segment       364..398
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        399..>436
                     /gene="IGLC"
BASE COUNT           83 a          140 c          120 g           93 t
ORIGIN      
        1 acatggggcc tcagccatgg ccgggaccct tctcctcctc ggcctccttg cttactgcac
       61 agtctctgcg gtctcctatg agctgactca gccaccctcg gtgtcagtgt ccccaggaca
      121 gacggccagg atcacctgtg ggggggacaa cattggaact gaatatgtgc actggtacca
      181 gcagaagcca ccgcaggccc ctgtggtggt catctattat aatactgacc ggccctcagg
      241 gatccctgag cgattctcag gctccaaatc agggaacacc ggcaccctga ccatcagcgg
      301 ggtcgaggcc ggggatgagg ctgactatta ctgtcaggtg tgggacagta ttactgatca
      361 ttccatcttc ggtgctggga cccggctcac cgtcctaggt cagcccaagg cttcccccac
      421 ggtcactctg ttcccg
//
LOCUS       KCVO01001228             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:13296:12098
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001228
VERSION     KCVO01001228.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13296:12098"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73257.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          161 c          126 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcggaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001229             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:10717:11817
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001229
VERSION     KCVO01001229.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10717:11817"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73258.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          143 c          139 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctcactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggaggca
      181 atgttggaag tgaatatgtc cactggtatc aacagaagcc accgcaggcc cctgtggtgg
      241 tcattcatta taatactgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt aggagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001230             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:26039:12480
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001230
VERSION     KCVO01001230.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:26039:12480"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73259.1"
                     /translation="DYYCQVWDSSSDHILF"
     J_segment       395..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          145 c          136 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagacg
      181 accttggaga taaatatgta cactggtacc agcagaagcc accacgggcc cctgtgttgg
      241 tcatctacta tgatactgac cggccctcat ggatccctga gcgattctct gggtccaaat
      301 cagggaacac cgccatcctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc atatcttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001231             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:10413:13565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001231
VERSION     KCVO01001231.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:10413:13565"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73260.1"
                     /translation="DYYCSSTDRSGNHVF"
     J_segment       392..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          143 c          124 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccaaca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagaagtg gtaatcatgt tttcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001232             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:22496:14788
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001232
VERSION     KCVO01001232.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:22496:14788"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73261.1"
                     /translation="DYYCGAWDGSLSARLF"
     J_segment       410..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          156 c          130 g          108 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gaccccgggc agagggtcac catctcgtgc
      181 actgggagca gctccaacat tggaggttat cttgtatatt ggtaccagca gttcccagga
      241 acagccccca aactcctcat ctatgacaat aataagcgac cctcagggat ttctgaccga
      301 ttctctggct ccaagtctgg tacctcagcc tccctgacca tcactgggct ccagcctggg
      361 gatgaggctg attattactg cggagcatgg gatggcagcc tgagtgctcg cttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01001233             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:18698:10579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001233
VERSION     KCVO01001233.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:18698:10579"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73262.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       393..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           99 a          136 c          124 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgtatatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac aacaaacggc cctctgggat tcctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaaggtg actactactg
      361 ttactcaaga gatagtagtg aaaatcaaag tgtcttcggt gctgggaccc ggctcagcgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001234             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:12853:3857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001234
VERSION     KCVO01001234.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12853:3857"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73263.1"
                     /translation="DYYCHSLDTSGNDVF"
     J_segment       378..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           89 a          139 c          117 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttactggtt ccagcagaag ccaggccagt cccctgtggt gatcatctat gaggacacca
      241 aacgggcctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgtcat tcattagata
      361 ccagtggtaa tgatgttttc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001235             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:24057:5501
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001235
VERSION     KCVO01001235.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:24057:5501"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73264.1"
                     /translation="DYYCSSYADTYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           80 a          161 c          118 g          113 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggcaccag
      181 cagtgacatc ggtggttata actttgtctc ctggtaccaa caccatccag gcacagcccc
      241 caaactcgtt atttatgagg tcactcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacgcgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgctcctcat atgcagacac ttacactttt gtgttcggaa gtggcaccaa
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01001236             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:17353:14275
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001236
VERSION     KCVO01001236.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:17353:14275"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73265.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       390..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          144 c          123 g          101 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctctgagctg acacagccac
      121 cctcggtgtc agtgtccccc ggacagacgg ccaggatcac ctgctctgga aatgcattgc
      181 caaaatacta tgcttattgg ttccagcaga agccaggcca gtcccctgtg gcgatcatct
      241 atgaggacaa caaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc agtggggccc aggtagagga tgaggctgac tactactgtt
      361 actcaacaga tagcagtggt actaatggtt tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001237             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:8418:7005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001237
VERSION     KCVO01001237.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:8418:7005"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73266.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           89 a          139 c          118 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatcaat gaggacagca
      241 aacggccctc tgggattcct gggagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gtagtggtaa ttatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001238             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:27143:9016
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001238
VERSION     KCVO01001238.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:27143:9016"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..423
                     /note="immunoglobulin light chain variable region"
     V_region        105..423
     V_segment       105..386
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <354..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73267.1"
                     /translation="DYYCQSTDSSGFIF"
     J_segment       389..423
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT          101 a          134 c          120 g          106 t
ORIGIN      
        1 acatgggggg ctgtggttct aggaggaaga gctctgggtg tctcaccatg acctggacca
       61 ctgttctgct cccctttctc actctctgca caggctctgt ggcctcctat gagctgacac
      121 agccaccctc agtgtcagtg tccccaggac agacggccag gatcacctgc tctggagaaa
      181 tactgacaaa aaattatgct cagtggttcc agcagaagcc aggccaggcc cctgtgttgt
      241 tgatatataa agacagtgag aggccctcag ggatccctga gcgattctct agctccagtt
      301 cagggacaac agttaccttg accatcagtc gggcccaggt agaagatgag gctgactatt
      361 attgtcaatc aacagacagc agtggtttca tcttcggtgc tgggacccgg ctcaccgtcc
      421 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCVO01001239             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:13195:12854
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001239
VERSION     KCVO01001239.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:13195:12854"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73268.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           89 a          141 c          118 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggctcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aaggtgacta ctactgttcc tcaacagata
      361 gcagtggtaa ttatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001240             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:17818:15592
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001240
VERSION     KCVO01001240.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17818:15592"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73269.1"
                     /translation="DYYCHSLDTSGNDVF"
     J_segment       378..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           89 a          141 c          116 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttactggtt ccagcagaag ccaggccagt cccctgtggc gatcatctat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgtcat tcattagata
      361 ccagtggtaa tgatgttttc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001241             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:14824:22300
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001241
VERSION     KCVO01001241.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14824:22300"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73270.1"
                     /translation="DYYCAAWDDSLSSPLF"
     J_segment       393..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          150 c          117 g          109 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagtttcaac
      181 attggaagta attatgtaaa ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 atctatttta gtaatcagcg gccctcaggg gtccctgccc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcat gggatgatag tctgagcagt cccttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001242             368 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:20400:2448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001242
VERSION     KCVO01001242.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 368)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20400:2448"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..330
                     /note="immunoglobulin light chain variable region"
     V_region        9..330
     V_segment       9..293
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <258..>302
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73271.1"
                     /translation="DYYCYSTDSSGNGLF"
     J_segment       294..330
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        331..>368
                     /gene="IGLC"
BASE COUNT           83 a          108 c          100 g           77 t
ORIGIN      
        1 acatgggctc caatgagctg acacagccac cctcgttgtc agtgtcccca ggacagacgg
       61 ccaggatcac ctgctctgga gatgcattgc cagaaaaatt tgcttattgg taccagcaga
      121 aaccaggcca gtcccctgtg ttgatcatct atgaggacag caaacggccc tctgggatcc
      181 ctgagagatt ctctggctcc agctcaggga cagtggccac cttgactatc agtggggccc
      241 aggtggagga tgaagctgac tactactgtt actcaacaga cagcagtggt aatggcttat
      301 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      361 tcttcccg
//
LOCUS       KCVO01001243             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:24199:18755
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001243
VERSION     KCVO01001243.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:24199:18755"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73272.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           91 a          142 c          117 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gacgacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcat tggggcccag gtggaggatg aagctgacta ccactgtttc tcaacagata
      361 gtagtggtaa tcataggggc ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001244             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:22722:19133
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001244
VERSION     KCVO01001244.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:22722:19133"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73273.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          157 c          120 g          112 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtacttata actatgtctc ctggtaccaa cagcatccag gcacagcccc
      241 caaactcatg atttttgagg tcagtgagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgctgctcat atgcagacac ctacactttt gtgtttggag gtggcaccag
      421 attgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01001245             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:10212:19174
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001245
VERSION     KCVO01001245.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:10212:19174"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73274.1"
                     /translation="DYYCQSGDSSANHYIF"
     J_segment       389..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          101 a          136 c          123 g          103 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gggaaatact
      181 ggcaaaaaaa tatgctcggt ggttccagca gaagccaggc caggcccctg ttctggtgat
      241 atataaggac actgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacattagtt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagga gacagcagtg ctaatcatta catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001246             328 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:25457:9765
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001246
VERSION     KCVO01001246.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 328)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 328)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:25457:9765"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..290
                     /note="immunoglobulin light chain variable region"
     V_region        7..290
     V_segment       7..253
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <215..>262
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73275.1"
                     /translation="DYYCQSFDSTLRAWVF"
     J_segment       254..290
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        291..>328
                     /gene="IGLC"
BASE COUNT           68 a          102 c           83 g           75 t
ORIGIN      
        1 acatgggagg gtcaccatcg cctgcactgg gagcagctcc aacattggag gtcactatgt
       61 gcagtggtac catcaactct caggaacggc ccccaaactc ctcatctatg aaaatgataa
      121 gcgaccctca ggggtttctg atcgattctc tggctcccag tctggaacct cagcctccct
      181 gaccatcaat ggactccagt ctgaggatga ggctgattat tactgccagt cctttgactc
      241 cacattgagg gcttgggtat tcggcggagg gacccggctg accgtcctag gtcagcccaa
      301 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001247             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:24538:8271
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001247
VERSION     KCVO01001247.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:24538:8271"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73276.1"
                     /translation="DYYCAAWDDSLNSPFF"
     J_segment       413..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           93 a          160 c          119 g          109 t
ORIGIN      
        1 acatggggac cttcagctgc gggtacagaa ggcaggactc aggataatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag ccaccctcaa cgtctggggc tcccgggcag agtgtcacca tctcttgctc
      181 tggaagcagc tccaacattg gaagtaatta tgtaaactgg taccagcaac tcccaggaac
      241 ggcccccaaa ctcctcatct attttactaa tcagcgaccc tcaggggtcc ctgaccgatt
      301 ctctggctct aagtctggca cctcagcctc cctggccatc actggtctcc gatctgagga
      361 tgaggctgat tattactgtg cggcatggga tgacagcctg aacagtccct tcttcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01001248             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1101:6907:4297
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001248
VERSION     KCVO01001248.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:6907:4297"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73277.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          161 c          119 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaccacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001249             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:19658:4370
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001249
VERSION     KCVO01001249.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19658:4370"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73278.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          144 c          139 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctcactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggaggca
      181 atgttggaac tgattatgtc cactggtatc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccttcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gccgactatt
      361 actgtcaggt gtgggacagt aggagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001250             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:12533:10661
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001250
VERSION     KCVO01001250.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12533:10661"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73279.1"
                     /translation="DYYCSSTDTSGNHVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           91 a          143 c          124 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tttgcttatt ggttccagca gaagtcaggc cagtcccctg tgttgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gataccagtg gtaatcatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001251             413 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:12522:14352
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001251
VERSION     KCVO01001251.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 413)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:12522:14352"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    172..375
                     /note="immunoglobulin light chain variable region"
     V_region        172..375
     V_segment       172..336
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <300..>347
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73280.1"
                     /translation="DYYCGAWDSSLSVRLF"
     J_segment       340..375
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        376..>413
                     /gene="IGLC"
BASE COUNT           78 a          135 c          103 g           97 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagaag cagaatcatg
      121 attcctgtgt ctcttccact tccagggtcc tgggcccagt ctgtgctgac gcagccccca
      181 aactcctcat ctatgacaat aataagcgac cctcagggat ttctgaccga ttctctggct
      241 ccaagtctgg tacctcagcc tccctgacca tcactgggct ccagcctggg gatgaggctg
      301 attattactg cggagcatgg gatagcagcc tgagtgttcg cttattcgga ggagggaccc
      361 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001252             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:14659:12588
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001252
VERSION     KCVO01001252.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14659:12588"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..452
                     /note="immunoglobulin light chain variable region"
     V_region        111..452
     V_segment       111..416
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73281.1"
                     /translation="DYYCQSYDSNLSAWVF"
     J_segment       417..452
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        453..>491
                     /gene="IGLC"
BASE COUNT           94 a          157 c          129 g          111 t
ORIGIN      
        1 acatggggct tcagctgtgg gcacaggagg cagcactcag gacagtctcc agcatggcct
       61 ggtctcctct cctcctcacc cttctcattc actgcacagg gtcctgggcc cagtctgtgc
      121 tgacgcagcc gccctcagtg tctggggcgc ccgggcagag ggtcaccatc tcctgcactg
      181 ggagcaactc caacattggg ggttttcatg tgcagtggta tcagcagcgg taccagcagc
      241 ttccaggaac ggcccccaaa ctcctcatct atgaaaataa taaacgacct tcagggattt
      301 ctgatcgatt ctctggctcc aagtctggga cctcagcctc cctgaccatc actggactcc
      361 agtctgagga tgaggctgat tattactgcc agtcctatga cagcaacttg agtgcttggg
      421 ttttcggcgg agggacccgg ctgaccgtcc taagtcagcc caaggctgcc ccctcggtca
      481 ctctcttccc g
//
LOCUS       KCVO01001253             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:15179:13956
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001253
VERSION     KCVO01001253.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15179:13956"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73282.1"
                     /translation="DYYCCSYRSGNTYVF"
     J_segment       399..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          153 c          125 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcgggacgtc tccaccatgg cctgggctct
       61 gctcctcctc agcctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttata atgacgtctc ctggtaccac cagcacgcag gcacagcccc
      241 cagactcctg atttatgatg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctggc catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgctgctcat ataggagtgg aaacacttat gtgttcggaa gtggcaccaa
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01001254             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:25769:9535
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001254
VERSION     KCVO01001254.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:25769:9535"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73283.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           92 a          144 c          124 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctctgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga aatgcattgc
      181 cagaatacta tgcttattgg ttccagcaga agccaggcca gtcccctgtg gcgatcatct
      241 atgaggacaa caaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc agtggggccc aggtagagga tgaggctgac tactactgtt
      361 actcaacaga tagcagtggt actaatggct tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001255             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:10815:14049
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001255
VERSION     KCVO01001255.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:10815:14049"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73284.1"
                     /translation="DYYCSSTDSSGSYVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           91 a          142 c          126 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtctcctg tactgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gacagtagtg gtagttatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001256             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:14010:2632
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001256
VERSION     KCVO01001256.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14010:2632"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73285.1"
                     /translation="DYYCYSTDNTDTHRGFF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           92 a          143 c          125 g          106 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc tcctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaaggcaggc cagtcccctg tgttgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggtt ccagttcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaacc gataacactg atactcatag gggcttcttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001257             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:19421:8579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001257
VERSION     KCVO01001257.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19421:8579"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..385
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73286.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       388..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           85 a          142 c          139 g           97 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactgcac agactctgtg gtctcctatg aattgactca
      121 gccacgctca gtgtccgtgt ccccaggaca gacggccagg atcacctgtg ggggagacag
      181 cattggaagt acaagtgtgc agtggtacca gcagaagcca ccgccggccc ttgtactggt
      241 catctatgct gatagcgaac ggccctcagg gatccctgag cgattctctg gctccaattt
      301 agggaatacc gccaccctga ccatcagcgg cgtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta gtagtgatgt gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001258             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:18158:9140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001258
VERSION     KCVO01001258.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18158:9140"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73287.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       391..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          143 c          125 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac aacatacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccagggggag gatgaagctg actactactg
      361 ttattcaatg gatagcagtg gtactcagag catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001259             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:23743:10309
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001259
VERSION     KCVO01001259.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:23743:10309"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73288.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       391..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          144 c          126 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcagacggc cctctgggat ccctgagaga ttctctgcct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccagggggag gatgaagctg actactactg
      361 ttattcaatg gatagcagtg gtactcagag catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001260             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:7403:5546
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001260
VERSION     KCVO01001260.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:7403:5546"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73289.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           90 a          142 c          117 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagcctccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatctcct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag gcaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ttcagggaca atggccacct
      301 tgactatcag tggggcccag gtggaggatg acgctgacta ctactgttac tcaacagata
      361 acagtgatac tcataggggc ttcttcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001261             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:19841:10986
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001261
VERSION     KCVO01001261.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19841:10986"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73290.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       397..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           88 a          143 c          139 g           98 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acaggctctg cggtctccta tgagctcact
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg tgggggaggc
      181 aatgttggaa gtgaatatgt ccactggtat caacagaagc caccgcaggc ccctgtggtg
      241 gtcatctatt ataatactga ccggccctca gggatccctg agcgattctc tggctccaaa
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tttgggacag taggagtgat catagtttat tgggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001262             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:2193:10061
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001262
VERSION     KCVO01001262.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:2193:10061"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73291.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          154 c          126 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtggtt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtaa tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catatgcaag cagtagcact tgggttttcg gcggagggac
      421 ccggctgacc gtcctaggtc aggccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001263             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:17642:14064
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001263
VERSION     KCVO01001263.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:17642:14064"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..455
                     /note="immunoglobulin light chain variable region"
     V_region        122..455
     V_segment       122..415
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73292.1"
                     /translation="DYYCLSYDSSLSAHYIF"
     J_segment       418..455
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           96 a          166 c          121 g          110 t
ORIGIN      
        1 acatgggggg gaagctctgc ttcagctgtg ggcacaggag gcagcactca ggacagtctc
       61 cagcatggcc tcgtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc
      121 ccagtctgtg ctgacacagc caccctcagt gtctggggcc ccagggcaga gggtcaccat
      181 ctcgtgcact gggagcagct ccagcattgg aggtgattat gtttcctggt accaacagct
      241 cccaggaacg acccccaaac tcctcatcta tcaaaataat aagcgaccct caggggtttc
      301 tgaccgattc tctggctcca agtctggtac ctcagcctcc ctgaccatca ctggactcca
      361 gactgaggat gaggctgatt actactgcct gtcctatgac agcagcctga gtgctcatta
      421 catcttcggt cctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt
      481 cactctgttc ccg
//
LOCUS       KCVO01001264             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:21627:14956
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001264
VERSION     KCVO01001264.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21627:14956"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73293.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           87 a          155 c          123 g          108 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtaatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca gtagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001265             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:8785:8994
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001265
VERSION     KCVO01001265.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8785:8994"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73294.1"
                     /translation="DYYCAAWDDSLSSPLF"
     J_segment       409..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           93 a          158 c          121 g          109 t
ORIGIN      
        1 acatggggac cttcagctgc gggtacagaa ggcaggactc aggataatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag ccaccctcaa cgtctggggc tcccgggcag agtgtcacca tctcttgctc
      181 tggaagcagc tccaacattg gaagtaatta tgtaaactgg taccagcagc tcccaggaac
      241 ggcccccaaa ctcctcatct attttagtaa tcagcgaccc tcaggggtcc ctgaccgatt
      301 ctctggctct aagtctggca cctcagcctc cctggccatc actggtctcc gatctgagga
      361 tgaggctgat tattactgtg cagcatggga tgacagcctg agcagtccct tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01001266             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:12194:5044
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001266
VERSION     KCVO01001266.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12194:5044"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..434
                     /note="immunoglobulin light chain variable region"
     V_region        107..434
     V_segment       107..396
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73295.1"
                     /translation="DYYCCSYAGNYYMF"
     J_segment       397..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           84 a          158 c          123 g          107 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtagtt atgactatgt ctcctggtac caacagcatc caggcacagc
      241 ccccaaagtc atgatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgctgct catatgcagg caactattac atgttcggtg ctgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01001267             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:26857:10958
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001267
VERSION     KCVO01001267.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:26857:10958"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..455
                     /note="immunoglobulin light chain variable region"
     V_region        110..455
     V_segment       110..416
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73296.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       419..455
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           91 a          167 c          126 g          109 t
ORIGIN      
        1 acatggggag cccaaccctg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct
       61 gactcctctc ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct
      121 gactcagcca ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct
      181 gagcagtgac ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag
      241 cgctcccagg ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt
      301 ccccaatcga gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc
      361 tgggctccag cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtactggagt
      421 gttgttcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCVO01001268             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:16940:11586
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001268
VERSION     KCVO01001268.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:16940:11586"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..394
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73297.1"
                     /translation="DYYCCSYAGRYLF"
     J_segment       395..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           82 a          159 c          123 g          102 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccac
      181 cagtgacatc ggtggctcta actatgtctc ctggtaccaa cagcatccag gcacagcccc
      241 caaattcatg atttatgagg tcagtaagcg gccctcaggg gtctcgaatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgctgctcat atgcaggcag gtacttattc ggaggcggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001269             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:20240:5011
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001269
VERSION     KCVO01001269.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20240:5011"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73298.1"
                     /translation="DYYCSSYSSSSTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          157 c          124 g          108 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tccgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catactcaag cagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001270             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:14246:16507
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001270
VERSION     KCVO01001270.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14246:16507"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73299.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           84 a          157 c          120 g          114 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtactt ataactatgt ctcctggtac caacagcatc cagacacagc
      241 ccccaaactc atgatttttg aggtcagtga gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgttgct catatgcaga cacctacact tttgtgtttg gaggtggcac
      421 cagattgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001271             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:21790:11290
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001271
VERSION     KCVO01001271.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21790:11290"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73300.1"
                     /translation="DYYCQVWDSSSDHCLL"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          142 c          139 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgac ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaatg
      181 ttggaagtga atatgtgcac tggtaccaac agaggccacc gcaggcccct gtggtggtca
      241 tccattataa tagtgaccgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatcatt gtttattggg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001272             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:7285:10562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001272
VERSION     KCVO01001272.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7285:10562"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..433
                     /note="immunoglobulin light chain variable region"
     V_region        104..433
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73301.1"
                     /translation="DYYCSSFTGRSTWVF"
     J_segment       399..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>472
                     /gene="IGLC"
BASE COUNT           88 a          154 c          119 g          111 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa caattcccag gcaaaacccc
      241 caaactcatg atttttgaag tcagtaatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctgga ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat tcacaggcag gagcacttgg gttttcggcg gagggacccg
      421 gctgaccgtc ctaagtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001273             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:15475:10357
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001273
VERSION     KCVO01001273.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15475:10357"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73302.1"
                     /translation="DYYCQVWDITTDHDVF"
     J_segment       391..427
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           96 a          141 c          127 g          101 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatgac ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggttctgcgg cctcctatga gctgactcag
      121 ccaccctcgg tgtcaatgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagca aaaatgtaca ctggtaccag caaaagccac cgcaggcccc tgtactggtc
      241 atctattatg atgtccaacg gccctcaggg atccctgagc gattctctgg cgccaaatca
      301 gggaacaccg ccaccctgat catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacattac tactgatcat gatgtgttcg gaagtggcac caagttgacc
      421 gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001274             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:15140:3185
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001274
VERSION     KCVO01001274.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:15140:3185"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73303.1"
                     /translation="DYYCQVWDSSSDHPIF"
     J_segment       395..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           81 a          147 c          137 g          102 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagtctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac ggacggccac gatcacctgt gggggagaca
      181 tcgttggaag tgaatatgtt cactggtatc agcagaagtc agcgcaggcc cctgtggtgg
      241 tcatctatta ttattctgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggagcac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactact
      361 actgtcaggt gtgggacagt agtagtgatc atcccatctt cggtgctggg acccggctca
      421 gcgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01001275             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:16518:7722
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001275
VERSION     KCVO01001275.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16518:7722"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73304.1"
                     /translation="DYHCQVWDSSSDVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          143 c          141 g           94 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 ggattggaag tagaagcgtg cagtggtacc agcagaagcc accgcaggcc cttgcactgg
      241 tcatctatgc tgatagcgaa cggccctcag ggatccctga gcgcttctct ggctccaatc
      301 tagggaacac cgccaccctg actattagcg gcgtcgaggc cggggatgag gctgactatc
      361 actgtcaggt gtgggacagt agtagtgatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001276             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:8047:16174
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001276
VERSION     KCVO01001276.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8047:16174"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73305.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           83 a          141 c          142 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctccttt gaattgactc
      121 agccacgctc agtgtccgtg tccccagggc agacggccag gatcacctgt gggggagaca
      181 ctattggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttctgctgg
      241 tcatgtatgc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 taggggacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001277             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:3356:11599
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001277
VERSION     KCVO01001277.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:3356:11599"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73306.1"
                     /translation="DYYCSSYAGTSTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          156 c          124 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagtacc caggcaaagc
      241 ccccaaactc ataatttatg aggtcagtaa tcggccctca ggggtctctg atcgcttctc
      301 tggttctaag tctggcaaca cggcctccct gagcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacgcagg cactagcact tgggtcttcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001278             415 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:19986:8854
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001278
VERSION     KCVO01001278.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 415)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:19986:8854"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..377
                     /note="immunoglobulin light chain variable region"
     V_region        87..377
     V_segment       87..337
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>349
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73307.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       341..377
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        378..>415
                     /gene="IGLC"
BASE COUNT           88 a          127 c          113 g           87 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagt gtccccagga cagacggcca ggatcacctg
      121 ctctggagat gcattgccag aaaaatatgc ttattggtac cagcagaaac caggccagtc
      181 ccctatgctg atcatctgtg aggacagcaa acggccctct gggatccctg aaagattctc
      241 tggctccagc tcagggacag tggccacctt gactatcact ggggcccagg tggaggatga
      301 agctgactac tactgttact cagcagacaa cagtggtcag ggctcattcg gaggagggac
      361 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001279             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:17888:8445
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001279
VERSION     KCVO01001279.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17888:8445"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..427
                     /note="immunoglobulin light chain variable region"
     V_region        101..427
     V_segment       101..393
                     /gene="IGLV10-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73308.1"
                     /translation="DYYCSTWDSSLSAVLF"
     J_segment       395..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>469
                     /gene="IGLC"
BASE COUNT          102 a          159 c          124 g           84 t
ORIGIN      
        1 acatgggggc agagcttcgg caagcacagt gggaatccgc accatgccct gggctctgct
       61 cctcctgacc ctcctcactc actctgcagt gccagtggtc caggcagggc tgactcagcc
      121 accctcagtg tccaagggct tgagacagac ggccacactc acctgcattg gaaacagcaa
      181 caatgttggc aaccagggag cagcttggct gcagcagcac cagggccacc ctcccaaact
      241 gctgtcctac aggaataaca accggccctc cgggatctca gagagattct ctgcatccag
      301 gtcaggaatc acagcctccc tgaccatcac cggactccaa cctgaggatg aggctgacta
      361 ttactgctca acatgggaca gcagcctcag tgccgtgtta ttcggagggg ggacccggct
      421 gaccgtcgta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001280             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:21159:19028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001280
VERSION     KCVO01001280.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:21159:19028"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..390
                     /note="immunoglobulin light chain variable region"
     V_region        87..390
     V_segment       87..356
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <318..>362
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73309.1"
                     /translation="DYYCSSTDTSGNHVF"
     J_segment       357..390
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        391..>428
                     /gene="IGLC"
BASE COUNT           86 a          137 c          110 g           95 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccac cttgactctc agtggggccc
      301 aggtggagga tgaaggtgac tactactgtt cctcaacaga taccagtggt aatcatgtat
      361 tcggcggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      421 tcttcccg
//
LOCUS       KCVO01001281             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:15810:12904
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001281
VERSION     KCVO01001281.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15810:12904"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73310.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          125 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggcgacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001282             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:7635:6878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001282
VERSION     KCVO01001282.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:7635:6878"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..389
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73311.1"
                     /translation="DYYCDSWESSGTHVF"
     J_segment       390..423
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          136 c          129 g          103 t
ORIGIN      
        1 acatgggggt aggctcagaa gcagagctct ggggtgtctc caccatggcc tggactcctc
       61 tctggctcac cctcctcagc ctttgcacag gttctgtggt ttcttctgag ctgactcagg
      121 accctgcagt gtctgtggcc ttgggacaga cagtcaggat cacttgccaa ggagacagcc
      181 tcagaagcta ttatgcaagc tggtaccagc agaagccagg ccaggcccct gtgctggtcg
      241 tctatgataa gaacaaccgg cccccaggga tcccagagcg attctctggc tccagctcag
      301 gaaacacagc ttccttgacc atcactgggg ctcaggtgga agatgaggct gactattact
      361 gtgactcctg ggaaagcagc ggtacccatg tgttcggagg tggcaccaag ttgaccgtcc
      421 tcggtcagcc taaggcttcc cccttggtca ctctgttccc g
//
LOCUS       KCVO01001283             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:15763:16640
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001283
VERSION     KCVO01001283.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:15763:16640"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73312.1"
                     /translation="DYYCYSTDTSGYHVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           92 a          140 c          124 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agtaaacggt cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggtc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gataccagtg gttatcatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001284             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:24655:11402
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001284
VERSION     KCVO01001284.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:24655:11402"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73313.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       395..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          141 c          139 g           96 t
ORIGIN      
        1 acatgggggc tggcctcggg aagcagcctt ggcggtgcct cagccatggc cgggaccctt
       61 ctcctcctcg gcctccttgc ttactgcaca gactctgcgg tctcctatga cctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaat
      181 gttggaagtg aatatgtgca ctggtaccaa cagaaaccag cgcaggcccc tgtggtggtc
      241 atccattata atagtgaccg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag tagtgatcat tgtgtattgg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001285             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:13641:10923
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001285
VERSION     KCVO01001285.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13641:10923"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73314.1"
                     /translation="DYYCQVWDSSTDHRVF"
     J_segment       393..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          149 c          140 g           91 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gtctcctatg agctgactca
      121 gccaccctcg ctgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 ccttggaagt aaatatgtgc actggtacca gcagaagcca acgcaggccc ctgtggtggt
      241 catcgattat gatagtgacc ggccctcagg gatccctgag cgattctctg gctccaaatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactacta
      361 ctgtcaggtg tgggacagta gtactgatca tcgggtattc ggcggaggga cccggctgac
      421 cgccctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001286             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:18455:3839
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001286
VERSION     KCVO01001286.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:18455:3839"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..408
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73315.1"
                     /translation="DYFCQVYDSSGTVF"
     J_segment       410..444
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           91 a          156 c          121 g          114 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc actcccaggt
      241 tattcctgta ctactactcc gactcagaca aagagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacg tcaagtaata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat ttctgtcagg tatatgacag tagtggtact gtgttcggaa
      421 gcggcaccaa gttgaccgtc ctcggtcagc ctaaggcttc ccccttggtc actctgttcc
      481 cg
//
LOCUS       KCVO01001287             526 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:12440:15610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001287
VERSION     KCVO01001287.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 526)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 526)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12440:15610"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    155..488
                     /note="immunoglobulin light chain variable region"
     V_region        155..488
     V_segment       155..448
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <413..>460
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73316.1"
                     /translation="DYYCSLWDSRLSSRVF"
     J_segment       453..488
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        489..>526
                     /gene="IGLC"
BASE COUNT          105 a          159 c          146 g          116 t
ORIGIN      
        1 acatggggac tctcagagta tgaagagggg cagggagaga tttggggaag ctctgcttca
       61 gctgtgggca caggaggcag cactcaggac agtctccagc atggcctggt ctctccttct
      121 cactctgctg gttcactgca cagggtcctg ggcccagtct gtgctgacgc agccgccctc
      181 agcatctggg gcccccgggc agagggtcac catctcctgc actgggacca gctccaacat
      241 cggggcgaat tattatgttt cctggtacca gcagttccca ggaacagccc ccaaactcct
      301 catgtatgaa aataataagc gaccctcagg ggtttctgac cgattctctg gctccaagtc
      361 tggtacctca gcctccctga ccatctctgg actccaatct gaggatgagg ctgattatta
      421 ctgctcacta tgggatagca ggctgagtag tcgggtattc ggcggaggga cccgactgac
      481 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001288             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:18299:11867
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001288
VERSION     KCVO01001288.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:18299:11867"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73317.1"
                     /translation="DYYCQSFDSSLSAVFF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           89 a          162 c          125 g          110 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgatga cgcagccgcc ctcactgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggacgt tattatgtgc aatggtacca gcagcttcca
      241 ggaacggccc ccacactcct catctatgaa aataataagc gaccctcagg gacttctgat
      301 cgattctctg gctcccagtc tggttcctca gcctccctga ccatcactgg actgcagtct
      361 gaggatgagg ctgattatta ctgccagtcc tttgacagca gcctgagtgc cgtgttcttc
      421 ggaggaggga cccgcctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01001289             441 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:8679:8183
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001289
VERSION     KCVO01001289.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 441)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 441)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8679:8183"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..403
                     /note="immunoglobulin light chain variable region"
     V_region        79..403
     V_segment       79..366
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <328..>375
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73318.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       371..403
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        404..>441
                     /gene="IGLC"
BASE COUNT           86 a          134 c          129 g           92 t
ORIGIN      
        1 acatggggcg gtgcctcagc catggccggg acccttctcc tcctcggcct ccttgcttac
       61 tgcacagact ctgcggtctc ctatgacctg actcagccac cctcggtgtc agtgtcccca
      121 ggacagacgg ccaggatcac ctgtggggga gacaatgttg gaagtgaata tgtgcactgg
      181 taccaacaga aaccagcgca ggcccctgtg gtggtcatcc attataatag tgaccggccc
      241 tcagggatcc ctgagcgatt ctctggctcc aaatcaggga acaccgccac cctgaccatc
      301 agcggggtcg aggccgggga tgaggctgac tattactgtc aggtgtggga cagtagtagt
      361 gatcattgtg tattgggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc
      421 ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001290             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:14913:21214
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001290
VERSION     KCVO01001290.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14913:21214"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73319.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       377..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           88 a          142 c          119 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaagtatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 gacggccctc tgggatccct gagggattct ctgcctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag ggggaggatg aagctgacta ctactgttat tcaatggata
      361 gcagtggtac tcagagcatc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001291             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:25866:11451
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001291
VERSION     KCVO01001291.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:25866:11451"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..446
                     /note="immunoglobulin light chain variable region"
     V_region        117..446
     V_segment       117..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73320.1"
                     /translation="DYYCQSFDSSLSAVLF"
     J_segment       411..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>485
                     /gene="IGLC"
BASE COUNT           88 a          158 c          131 g          108 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcactgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag caccgccaac attgggggtt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaagtcctc atctatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggaacctcag cctccctgac catcactgga ctccggtctg
      361 aggatgaggg tgattattac tgccagtcct ttgacagcag cctgagtgcc gtgttattcg
      421 gaggagggac ccggctgacc gtcctaagtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001292             418 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:10623:6044
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001292
VERSION     KCVO01001292.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:10623:6044"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    85..380
                     /note="immunoglobulin light chain variable region"
     V_region        85..380
     V_segment       85..344
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <308..>352
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73321.1"
                     /translation="DYYCSSYTDSSTWVF"
     J_segment       345..380
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        381..>418
                     /gene="IGLC"
BASE COUNT           82 a          137 c          105 g           94 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagtctcc tggacagtcg gtcaccattt cctgcactgg
      121 aaccagcagt gacattggtg gttataaccg tgtctcctgg taccaacagc acccaggcaa
      181 agcccccaaa ctcatgattt atgaggtcaa taatcggccc tcaggggtct ctgatcgctt
      241 ctctggctcc aagtctggca acacggcctc cctgatcatc tctgggttcc aggctgagga
      301 cgaggctgat tattactgca gctcatacac agacagtagc acttgggtat tcggcggagg
      361 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001293             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:13858:14885
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001293
VERSION     KCVO01001293.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13858:14885"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..447
                     /note="immunoglobulin light chain variable region"
     V_region        118..447
     V_segment       118..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73322.1"
                     /translation="DYYCQSYDSSLRAVLF"
     J_segment       412..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>486
                     /gene="IGLC"
BASE COUNT           91 a          157 c          131 g          107 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagaaggt caccatctcc
      181 tgcactggga gcaactccaa cgttggaggt tattatgtgc agtggtacca gcaacttcca
      241 ggaacggccc ccagagttct catctatgaa aataataagc gaccctcagg ggtttctgat
      301 cgagtctctg gctcccagtc gggtgcctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gcctgcgagc cgtgttattc
      421 ggaggaggga cccggctgac cgtcctaagt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01001294             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:12329:9550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001294
VERSION     KCVO01001294.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12329:9550"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73323.1"
                     /translation="DYYCQVYDGSAWVF"
     J_segment       408..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          160 c          125 g          110 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ctgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agaagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctcta ctacttctcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gatcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacgg tagtgcttgg gtattcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001295             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:20788:7341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001295
VERSION     KCVO01001295.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20788:7341"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73324.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       377..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           91 a          141 c          117 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaagtatg
      181 cttattggtt ccagcaaaag ccaggccagt cccctgtgct gatcatctat gaggacaaca
      241 gacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccgcct
      301 tgactatcag tggggcccag ggggaagatg aagctgacta ctactgttat tcaatggata
      361 gcagtggtac tcagagcatc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001296             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:17910:13034
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001296
VERSION     KCVO01001296.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17910:13034"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73325.1"
                     /translation="DYYCQVYDTTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          161 c          125 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcgtcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcaggtggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tatatgacac tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001297             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:6704:11203
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001297
VERSION     KCVO01001297.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:6704:11203"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..385
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73326.1"
                     /translation="DYYCQVWDSSSDVFF"
     J_segment       388..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           86 a          140 c          141 g           96 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactgcac agactctgtg gtctcctatg aattgactca
      121 ggcacgctca gtgtccgtgt ccccaggaca gacggccagg atcacctgtg ggggagacag
      181 cattggaagt agaagtgtac agtggtacca gcagaaggca ccgcaggccc ttgtactggt
      241 catctatgct gatagcgaac ggccctcagg gatccctgag cgattctctg gctccaattt
      301 agggaacacc gccaccctga ccatcagcgg cgtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta gtagtgatgt gttcttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001298             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:21852:10945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001298
VERSION     KCVO01001298.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21852:10945"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73327.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           87 a          155 c          123 g          108 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccagact gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca gtagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001299             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:7273:8319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001299
VERSION     KCVO01001299.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7273:8319"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73328.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          162 c          120 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc ctttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa caccacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac gtccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001300             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:8440:6740
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001300
VERSION     KCVO01001300.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:8440:6740"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..443
                     /note="immunoglobulin light chain variable region"
     V_region        114..443
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73329.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       408..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>482
                     /gene="IGLC"
BASE COUNT           92 a          154 c          128 g          108 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcctcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcac ctccaacatc ggaagtaaca gtgtgtcctg gtacctgcag ctcccagaaa
      241 cggctcccaa gctcctcatc tattataatg atcggcgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc ccgtcagcct ccctggccat cagtgggctc gagaccgaag
      361 atgaggctga ttattactgc gcagtatggg atgatagcct gagcggtgtg ttattcggag
      421 gagggacccg actgaccgtc ctaagtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001301             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:14327:12269
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001301
VERSION     KCVO01001301.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14327:12269"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73330.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       399..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          146 c          134 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagttgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaga taaatatcta cactggtacc accagaagcc agcgcaggcc cctgtgctgg
      241 tcatctacta tgatagtgac cggccctcat ggatccctga gcgattctct gggtccaagt
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt aataatgatc atatcttttt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001302             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:8044:21067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001302
VERSION     KCVO01001302.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8044:21067"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..258
                     /note="immunoglobulin light chain variable region"
     V_region        5..258
     V_segment       5..218
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <186..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73331.1"
                     /translation="DYYCQVWDSSSDVFF"
     J_segment       221..258
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        259..>296
                     /gene="IGLC"
BASE COUNT           61 a           84 c           90 g           61 t
ORIGIN      
        1 acatgggaga cagcattgga agtagaagtg tgcagtggta ccagcagaag ccaccgcagg
       61 cccttctact ggtcatctat gctgatagcg aacggccctc agggatccct gagcgattct
      121 ctggctccaa tttagggaac accgccaccc tgaccatcag cggcgtcgag gccggggatg
      181 aggctgacta ttactgtcag gtgtgggaca gtagtagtga tgtgttcttc ggaggaggga
      241 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001303             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:11921:16249
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001303
VERSION     KCVO01001303.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:11921:16249"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73332.1"
                     /translation="DYYCYSTISSGNERIF"
     J_segment       378..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           94 a          137 c          115 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 tttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacaatta
      361 gtagtggtaa tgaaaggatc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001304             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:5333:7444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001304
VERSION     KCVO01001304.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:5333:7444"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..390
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73333.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           87 a          152 c          124 g          103 t
ORIGIN      
        1 acatggggga caggaggcgg cactcaggac agtctccagc atggcctggt ctcctctcct
       61 cctcaccctt ctcattcact gcacagggtc ctgggcccag tctgtgctga cgcagccgcc
      121 ctcagtgtct ggggcgcccg ggcagagggt caccatctcc tgcactggga gcaactccaa
      181 cattggaggt tattatgtgc agtggtacca gcagcttcca ggaacggccc ccaaactcct
      241 catgtatgaa aataataagc gaccctcagg ggtttctgat cgattctctg gctcccagtc
      301 tggtgcctca gcctccctga ccatcactgg actccagtct gaggatgagg ctgattatta
      361 ctgccagtcc tatgacagca gcctgagtgc cgtgttattc ggagcaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001305             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:13003:5981
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001305
VERSION     KCVO01001305.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:13003:5981"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73334.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           86 a          154 c          123 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagtacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001306             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:20402:2794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001306
VERSION     KCVO01001306.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:20402:2794"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73335.1"
                     /translation="DYYCAAWDDSLNSPFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          155 c          113 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg acagagtgtc accatctctt gctctggaag cagctccaac
      181 attggaagta attatgtaaa ctggtaccag caactcccag gaacggcccc caaactcctc
      241 atctatttta ctaatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcggcat gggatgacag cctgaacagt cccttcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001307             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:19099:8067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001307
VERSION     KCVO01001307.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19099:8067"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73336.1"
                     /translation="DYYCYSADSSGNGLF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           95 a          139 c          126 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcgtatt ggtatcagca gaaaccaggc cagtcccctg tgcatatcat
      241 ctatgaggac agcaagcggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtaatggctt attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001308             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:4737:10047
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001308
VERSION     KCVO01001308.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:4737:10047"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73337.1"
                     /translation="DYYCSAWDNSLSGYIF"
     J_segment       407..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           85 a          155 c          127 g          115 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccgggca gagggtcacc atctcgtgca
      181 ctgggagcag ctccaacatt ggaggttatt ctgtatcctg gtaccggcaa ctcccaggag
      241 cgggccccaa actcctcatc tttgaaaata ataagcgacc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggt gtctcagcct ccctttccat cactggactc cagtctgagg
      361 atgaggctga ttattactgc tcagcttggg ataacagcct gagtggttac atcttcggtt
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCVO01001309             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:16731:9397
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001309
VERSION     KCVO01001309.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16731:9397"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73338.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          155 c          125 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggagccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctctggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagcacttgg gttttcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001310             307 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:25439:11501
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001310
VERSION     KCVO01001310.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 307)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 307)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:25439:11501"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..269
                     /note="immunoglobulin light chain variable region"
     V_region        8..269
     V_segment       8..232
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <194..>241
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73339.1"
                     /translation="DYYCAAWDNSLSSPLF"
     J_segment       235..269
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        270..>307
                     /gene="IGLC"
BASE COUNT           65 a           97 c           75 g           70 t
ORIGIN      
        1 acatggggga agcagctcca acattggaag taattatgta tactggtacc agcagctccc
       61 aggaacggcc cccaaactcc tcatctattt tagtaatcag cgaccctcag gggtccctga
      121 ccgattctct gcctctaagt ctggcacctc agcctccctg gccatcactg gtctccgatc
      181 tgaggatgag gctgattatt actgtgcagc atgggataac agcctgagca gtcccttatt
      241 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      301 cttcccg
//
LOCUS       KCVO01001311             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:14748:20210
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001311
VERSION     KCVO01001311.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14748:20210"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73340.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           86 a          160 c          119 g          108 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtagttat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgac gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacgcaagca ctaccacttg gctattcggc ggagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001312             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:6953:15025
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001312
VERSION     KCVO01001312.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:6953:15025"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..424
                     /note="immunoglobulin light chain variable region"
     V_region        97..424
     V_segment       97..387
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73341.1"
                     /translation="DYYCAAWDDSLSSPLF"
     J_segment       390..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           90 a          148 c          115 g          109 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagtttcaac
      181 attggaagta attatgtaaa ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 atctatttta gtaatcagcg gccctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctcctccat cactggtctc cgatctgagg atgaggctga ttattactgt
      361 gcagcatggg atgatagtct gagcagtccc ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001313             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:11338:4470
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001313
VERSION     KCVO01001313.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:11338:4470"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..398
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73342.1"
                     /translation="DYYCSSYAGGNTIIF"
     J_segment       402..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           85 a          162 c          120 g          106 t
ORIGIN      
        1 acatgggggg gggtctcagg aggcggcact ctcgggacat ctccaccatg gcctgggatc
       61 tgctcctctt caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctccctc aatgtctggg tctcctggac agtcggtcac catcccctgc actggaacca
      181 gcagtgacat tggtgcttat gaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gactttcgag gtcagtcagc gtccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tgtcaacacg gcctccctga ccatctctgg gctccaggct gaggatgagg
      361 ctgattatta ctgcagctca tatgcaggcg gtaacactat aatcttcggt cctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001314             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:12608:7051
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001314
VERSION     KCVO01001314.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12608:7051"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..426
                     /note="immunoglobulin light chain variable region"
     V_region        99..426
     V_segment       99..391
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73343.1"
                     /translation="DYYCFVYYSGTQFF"
     J_segment       396..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           99 a          153 c          114 g           98 t
ORIGIN      
        1 acatggggga gccagagatc ccttccaata ccagcaccat ggcctggact ctgctcctcc
       61 tccagttcct cctcacttgc tgcccagggt ccaattctca ggctgtagtg actcaggagc
      121 cctcaatgac tgtgtcccca ggagggacag tcactctcac ctgtggctcc agcactggag
      181 cagtcaccag tggtaacttt ccaaactggt tccagcagaa acctggacaa gtccccaggg
      241 gactgattta caatacaaac aacaaacact cctggacccc tgcccggttc tcaggctccc
      301 tcgctggggg caaagctgcc ctgacactgt caggagcaca gcccgaggac gaggctgatt
      361 attactgctt cgtgtactat agtggtactc aattcttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001315             312 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:14830:15509
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001315
VERSION     KCVO01001315.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 312)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 312)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14830:15509"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..274
                     /note="immunoglobulin light chain variable region"
     V_region        5..274
     V_segment       5..235
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <199..>246
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73344.1"
                     /translation="DYYCYSMDSSTYLGFF"
     J_segment       237..274
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        275..>312
                     /gene="IGLC"
BASE COUNT           68 a           90 c           82 g           72 t
ORIGIN      
        1 acatgggtca cctgctctgg agatgcattg ccaaaaaaat acgcttattg gttccagcag
       61 aagccaggcc agtcccctgt attgatcatc tatgaggaca ccaaacggcc ctctgggatc
      121 cctgagagat tctctggctc cagctcaggg acagtggcca ccttgactat cagtggggcc
      181 caggtggagg atgaagctga ctactactgt tactcaatgg atagcagtac ttatcttggc
      241 ttcttcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      301 actctcttcc cg
//
LOCUS       KCVO01001316             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:12076:4355
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001316
VERSION     KCVO01001316.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:12076:4355"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73345.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          143 c          125 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 tccctcggtg tcagtgtccc caggacagac ggccaggatc tcctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaaggcaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagttcagg
      301 gacaatggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gataacagtg atactcatag gggcttcttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001317             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:8077:19197
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001317
VERSION     KCVO01001317.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8077:19197"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..446
                     /note="immunoglobulin light chain variable region"
     V_region        117..446
     V_segment       117..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73346.1"
                     /translation="DYHCQSYDSNLSAVLF"
     J_segment       411..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>485
                     /gene="IGLC"
BASE COUNT           92 a          156 c          129 g          108 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaagtt attatgtgca gtggtaccag caacttccag
      241 gaacggcccc caaagttctc atctatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ggcccagtct ggtacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattatcac tgccagtcct atgacagcaa cctgagtgcc gtgttattcg
      421 gaggggggac ccggctgacc gtcctaagtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001318             384 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:6154:11566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001318
VERSION     KCVO01001318.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 384)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 384)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..384
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:6154:11566"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..346
                     /note="immunoglobulin light chain variable region"
     V_region        13..346
     V_segment       13..309
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <274..>318
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73347.1"
                     /translation="DYYCQSADDSYNYIF"
     J_segment       310..346
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        347..>384
                     /gene="IGLC"
BASE COUNT           71 a          125 c          100 g           88 t
ORIGIN      
        1 acatgggggg ctgaggttgt gttcactcag ccccattctg tgtcggggtc tccggggcag
       61 acggtcacca tctcctgcac ccgcagcagt ggcagcattg acagtgaata tgtgcggtgt
      121 taccagcagc gcccgggcaa tgcccccacc acagtgattt acaaagataa ccaaagaccc
      181 tctggggtcc ctgatcggtt ctctggctcc attgacagct cctccaactc tgcctccctc
      241 gccatctctg ggctgaagtc tgaggacgag gctgactact actgtcagtc tgctgatgac
      301 agctacaatt acatcttcgg tgctgggtcc cggctcaccg tcctaggtca gcccaaggct
      361 tcccccacgg tcactctgtt cccg
//
LOCUS       KCVO01001319             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:14987:4004
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001319
VERSION     KCVO01001319.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14987:4004"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73348.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       392..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           91 a          144 c          127 g          102 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccaaaaaa gtatgcttat tggttccagc agaagccagg ccagtcccct gtgctgatca
      241 tctatgagga cagcagacgg ccctctggga tccctgagag attctctgcc tccagctcag
      301 ggacagtggc caccttgact atcagtgggg cccaggggga ggatgaagct gactactact
      361 gttattcaat ggatagcagt ggtactcaga gcatcttcgg tgctgggacc cggctcaccg
      421 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCVO01001320             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:24737:20625
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001320
VERSION     KCVO01001320.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:24737:20625"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73349.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       379..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           92 a          139 c          116 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaagtatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaagacgaca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaatagata
      361 gtagtggtag tcatagcgtc ttcggtgctg ggacccggct caccgtccta ggtcagccaa
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001321             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:14936:20125
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001321
VERSION     KCVO01001321.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14936:20125"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73350.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          141 c          125 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 caatgaggac agcaaatggc cctctgggat ccctgagaga atctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagtagtg gtaatcatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001322             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:26373:6843
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001322
VERSION     KCVO01001322.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:26373:6843"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73351.1"
                     /translation="DYFCAAWDDSLNSPFF"
     J_segment       413..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           91 a          160 c          120 g          110 t
ORIGIN      
        1 acatggggac cttcagctgc gggtacagaa ggcaggactc aggataatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag ccaccctcaa cgtctggggc tcccgggcag agtgtcacca tctcttgctc
      181 tggaagcagc tccaacattg gaagtaatta tgtaaactgg taccagcagc tcccaggaac
      241 ggcccccaaa ctcctcatct attttactaa tcagcgaccc tcaggggtcc ctgaccgatt
      301 ctctggctct aagtctggca cctcagcctc cctggccatc actggtctcc gatctgagga
      361 tgaggctgat tatttctgtg cggcatggga tgacagcctg aacagtccct tcttcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01001323             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:13685:14160
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001323
VERSION     KCVO01001323.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:13685:14160"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73352.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           92 a          141 c          125 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 caatgaggac agcaaacggc cctcttggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagtagtg gaaattatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001324             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:11397:10168
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001324
VERSION     KCVO01001324.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11397:10168"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73353.1"
                     /translation="DYYCYSTDSSGSTGLF"
     J_segment       388..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          144 c          123 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctctgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaatac tatgcttatt ggttccaaca gaagccaggc cagtcccctg tggcgatcat
      241 ctatgaggac aacaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc actttgacta tcagtggggc ccaggtagag gatgaagctg actactactg
      361 ttactcaaca gatagcagtg gttctactgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001325             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:16233:12329
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001325
VERSION     KCVO01001325.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:16233:12329"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..426
                     /note="immunoglobulin light chain variable region"
     V_region        97..426
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73354.1"
                     /translation="DYYCAVWDDSLSGLLF"
     J_segment       392..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>465
                     /gene="IGLC"
BASE COUNT           90 a          153 c          118 g          104 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcctc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcaacctccc
      121 tcagcgtctg aggccgccag gaagagtgtc atcatctcct gctctggaag cacctccaac
      181 atcggaagta atagtgtgtc ctggtacctg cagctcccag aaacggctcc caaactcctc
      241 atctattcta atgatcggcg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcccgtcag cctccctggc catcagtggg ctcgagaccg aagatgaggc tgattattac
      361 tgcgcagtat gggatgatag cctgagcggt ctgttattcg gaggagggac ccgactgacc
      421 gtcctacgtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001326             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:22196:17378
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001326
VERSION     KCVO01001326.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22196:17378"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73355.1"
                     /translation="DYYCQVWDSTNDHILF"
     J_segment       395..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          145 c          135 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaga taaatatgta cactggtacc agcagaagcc agcgcgggtc cctgtgttgg
      241 tcatctacta tgatagtgac cggccctcat ggatccctga gcgattctct gggtccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt actaatgatc atatcttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001327             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:15902:20481
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001327
VERSION     KCVO01001327.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:15902:20481"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73356.1"
                     /translation="DYYCQVWDITTDHDVF"
     J_segment       389..425
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           95 a          138 c          129 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatgacct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ttctgcggcc tcctatgagc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaaa aatgtacact ggtaccagca aaagccaccg caggcccctg tactggtcat
      241 ctattatgat gtcgaacggc cctcagggat ccctgagcga ttctctggcg ccaaatcagg
      301 gaacaccgcc accctgatca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattacta ctgatcatga tgtgttcgga agtggcacca agttgaccgt
      421 cctcggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01001328             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:11241:10835
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001328
VERSION     KCVO01001328.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11241:10835"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73357.1"
                     /translation="DYYCYSTDNYNYHRVFF"
     J_segment       384..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           92 a          142 c          114 g          104 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctggc acagccaccc tcggtatcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgctttgcca gaaaaatttg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtact gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggcggatg aagctgacta ctactgttac tcaacagata
      361 actataatta tcatagggtc ttcttcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001329             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:17121:2689
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001329
VERSION     KCVO01001329.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:17121:2689"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..395
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73358.1"
                     /translation="DYYCLLYSSGVHLF"
     J_segment       397..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           96 a          156 c          113 g          103 t
ORIGIN      
        1 acatggggtc tggagccaga gatcccttcc aataccagca ccatggcctg gactctgctc
       61 ctcctccagt tcctcctcac ttgctgccca gggtccaatt ctcaggctgt agtgactcag
      121 gagccctcaa tgactgtgtc cccaggaggg acagtcactc tcacctgtgg ctccagcact
      181 ggagcagtca ccagtagtaa ctttccaaac tggttccagc agaaacctgg acaagtcccc
      241 aggggactca tttacaatac acacaacaaa cactcctgga cccctgcccg gttctcaggc
      301 tccctcgctg gggccaaagc tgccctgaca ctgtcaggtg cacagcccga ggacgaggct
      361 gactattact gcttgctgta ttctagtggt gttcatttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001330             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:20248:12483
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001330
VERSION     KCVO01001330.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20248:12483"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73359.1"
                     /translation="DYYCAAWDDSLSSPLF"
     J_segment       397..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           90 a          153 c          119 g          107 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gataatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 accctcaacg tctggggctc ccgggcagag tgtcaccatc tcttgctctg gaagcagctc
      181 caacattgga agtaattatg tatactggta ccagcagctc ccaggaacgg cccccaaact
      241 cctcatctat tttagtaatc agcgaccctc aggggtccct gaccgattct ctggctctaa
      301 gtctggcacc tcagcctccc tggccatcac tggtctccga tctgaggatg aggctgatta
      361 ttactgtgca gcatgggatg acagcctgag cagtccctta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001331             506 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:10069:22137
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001331
VERSION     KCVO01001331.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 506)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 506)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..506
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:10069:22137"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    138..468
                     /note="immunoglobulin light chain variable region"
     V_region        138..468
     V_segment       138..431
                     /gene="IGLV8-111"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <396..>440
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73360.1"
                     /translation="DYYCAVYMGSGIDVF"
     J_segment       432..468
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        469..>506
                     /gene="IGLC"
BASE COUNT          102 a          157 c          131 g          116 t
ORIGIN      
        1 acatggggga aaaggccctg aggaaaacaa actccagctg agaagcctga gagcacttgg
       61 ccttcataag tgtccccacc atggcctgga tgatgcttct cctcggactc cttgcttatg
      121 gctcaggagt ggattctgag actgtggtga cccaggagcc atcgttgtca gtgtcccctg
      181 gaggaacagt cacactcacc tgtggcctga gctctggctc agtctctacc gataactacc
      241 ccagctggta ccagcagacc ccaggccagg ctccacgcat gctcctcttc aacaccaaca
      301 ctcgcccttc tggggtccct actcgcttct ctggctccat ccttgggaac aaagctgccc
      361 tcaccgtcac gggggctcag gcagacgatg aatctgatta ttactgtgcg gtgtacatgg
      421 gtagtggcat tgatgtgttc ggaagtggca ccaagttgac cgtcctcggt cagcccaagg
      481 cttccccctt ggtcactctg ttcccg
//
LOCUS       KCVO01001332             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:22465:5033
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001332
VERSION     KCVO01001332.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22465:5033"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73361.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           86 a          160 c          119 g          108 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgac gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca ctaccacttg gctattcggc ggagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001333             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:6816:7455
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001333
VERSION     KCVO01001333.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:6816:7455"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73362.1"
                     /translation="DYYCSSYTDSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          154 c          123 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtaatcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgat catctctggg ttccaggctg aggacgaggc
      361 tgattattat tgcagctcat acacagacag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001334             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:15509:14129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001334
VERSION     KCVO01001334.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:15509:14129"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73363.1"
                     /translation="DYYCGTWDSSLSARLF"
     J_segment       412..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          157 c          129 g          108 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggaccccgg gcagagggtc accatctcgt
      181 gcactgggag cagctccaac attggaggtt attttgtata ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctatgaca ataataagcg accctcaggg atttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagcctg
      361 gggatgaggc tgattattac tgcggaacat gggatagcag cctgagtgct cgcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001335             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:12583:15700
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001335
VERSION     KCVO01001335.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12583:15700"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    56..386
                     /note="immunoglobulin light chain variable region"
     V_region        56..386
     V_segment       56..350
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <314..>358
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73364.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       351..386
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        387..>424
                     /gene="IGLC"
BASE COUNT           82 a          139 c          109 g           94 t
ORIGIN      
        1 acatgggggt ccagggaagc agaagcctct gagcccaggc ccaggatcct gggctcaggc
       61 tgccctgact cagtctccct ctgtgtctgg gtctcctgga cagtcggtca ccatttcctg
      121 cactggaacc agcagtgaca ttggtggtta taaccgtgtc tcctggtacc aacagcaccc
      181 aggcaaagcc cccaaactca tgatttatga cgtcagtgat cggccctcag gggtctctga
      241 tcgcttctct ggttccaagt ctggcaacac gacctccctg atcatctctg ggctccaggc
      301 tgaggacgag gctgattatt actgcagctc atacacaagc actaccactt ggctattcgg
      361 cggagggacc cgcctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      421 cccg
//
LOCUS       KCVO01001336             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:3213:9446
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001336
VERSION     KCVO01001336.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:3213:9446"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..423
                     /note="immunoglobulin light chain variable region"
     V_region        105..423
     V_segment       105..384
                     /gene="IGLV3-38"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73365.1"
                     /translation="DYYCYSGDGNSWVF"
     J_segment       386..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           84 a          146 c          134 g           97 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgaacg tctcaccatg gcctggatcc
       61 ctctcctgct ccccctcctc gccctctgca caggctctgt ggcctcctat gagctgacac
      121 agccaccctc ggtttcggtg tccccgggac agacggccag gatcacctgc tctggagatg
      181 cattgccaaa aaattatgct cattggtacc agcagaagcc aggccaggtg cccgtgctgg
      241 tgatttataa agacagtgag cggccctcag ggattcctga acgtttctct ggctccagct
      301 cagggaccac agtcaccctg accgtcagcg gggcccaggc tgaggatgag gctgactatt
      361 actgttactc tggggatggc aacagttggg tattcggcgg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001337             314 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:21511:5720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001337
VERSION     KCVO01001337.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 314)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 314)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:21511:5720"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..276
                     /note="immunoglobulin light chain variable region"
     V_region        7..276
     V_segment       7..236
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <201..>248
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73366.1"
                     /translation="DYYCSLWDSRLSSRVF"
     J_segment       241..276
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        277..>314
                     /gene="IGLC"
BASE COUNT           68 a           95 c           78 g           73 t
ORIGIN      
        1 acatgggcac tgggaccagc tccaacatcg gggcgaatta ttatgtttcc tggtaccagc
       61 agttcccagg aacagccccc aaactcctca tgtatgaaaa taataagcga ccctcagggg
      121 tttctgaccg attctctggc tccaagtctg gtacctcagc ctccctgacc atctctggac
      181 tccaatctga ggatgaggct gattattact gctcactatg ggatagcagg ctgagtagtc
      241 gggtattcgg cggagggacc cgactgaccg tcctaggtca gcccaaggct gccccctcgg
      301 tcactctctt cccg
//
LOCUS       KCVO01001338             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:15080:20175
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001338
VERSION     KCVO01001338.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15080:20175"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..404
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73367.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       406..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           89 a          154 c          128 g          109 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagtt ccaacattgg aggttattat gtgcagtggt accagcagct tccaggaacg
      241 gcccccaaac tcctcatgta tgaaaataat aagcgaccct caggggtttc tgatcgattc
      301 tctggctccc agtctggtac ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgcca gtcctatgac agcagcctga gtgccgtgtt attcggagca
      421 gggacccggc tgaccgtcct aggtcagtcc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001339             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:18731:2315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001339
VERSION     KCVO01001339.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18731:2315"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73368.1"
                     /translation="DYYCSSYAGSITWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          156 c          125 g          108 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtaa tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gagcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacgcagg cagtatcact tgggtattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001340             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:2821:15307
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001340
VERSION     KCVO01001340.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:2821:15307"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73369.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       388..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          145 c          123 g          101 t
ORIGIN      
        1 acatggggtg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactccccc tcctcacttt ctgcacaggc tctgcagcct cctctgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agatgcattg
      181 ccaaaatact atgcttattg gttccagcag aagccaggcc agtcccctgt ggcgatcatc
      241 tatgaggaca acaaacggcc ctctgggatc cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cagtggggcc caggtcgagg atgaagctga ctactactgt
      361 tactcaacag atagcagtgg tactaatggc ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001341             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:13832:18339
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001341
VERSION     KCVO01001341.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:13832:18339"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..395
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73370.1"
                     /translation="DYYCFVYYSGTQFF"
     J_segment       400..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           99 a          155 c          115 g           99 t
ORIGIN      
        1 acatggggtc tggagccaga gatcccttcc aataccagca ccatggcctg gactctgctc
       61 ctcctccagt tcctcctcac ttgctgccca gggtccaatt ctcaggctgt agtgactcag
      121 gagccctcaa tgactgtgtc cccaggaggg acagtcactc tcacctgtgg ctccagcact
      181 ggagcagtca ccagtggtaa ctttccaaac tggttccagc agaaacctgg acaagtcccc
      241 aggggactga tttacaatac aaacaacaaa cacccctgga cccctgcccg gttctcaggc
      301 tccctcgctg ggggcaaagc tgccctgaca ctgtcaggag cacagcccga ggacgaggct
      361 gattattact gcttcgtgta ctatagtggt actcaattct tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001342             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:17798:22058
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001342
VERSION     KCVO01001342.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:17798:22058"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73371.1"
                     /translation="DYYCQVWDSSSAVLF"
     J_segment       386..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           85 a          144 c          136 g           96 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactgcacag actctgtggt ctcctatgaa ttgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacacca
      181 ttggaagtag aagtgtgcag tggtaccagc acaagccacc gcaggccctt gtactggtca
      241 tctatgctga taccgaacgg ccctcaggga tccctgagcg attctctggc tccaatttag
      301 ggaacaccgc caccctgacc atcagcggcg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgctgtgt tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001343             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:18358:10957
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001343
VERSION     KCVO01001343.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18358:10957"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73372.1"
                     /translation="DYYCHSLDTSGNDVF"
     J_segment       390..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           91 a          143 c          123 g          101 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 caaaaaaatt tgcttactgg ttccagcaga agccaggcca gtcccctgtg gcgatcatct
      241 atgaggacac caaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc agtggggccc aggtggagga tgaagctgac tactactgtc
      361 attcattaga taccagtggt aatgatgttt tcggcggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001344             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:7280:14050
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001344
VERSION     KCVO01001344.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7280:14050"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..437
                     /note="immunoglobulin light chain variable region"
     V_region        104..437
     V_segment       104..397
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73373.1"
                     /translation="DYYCGSYGSGSTHGLF"
     J_segment       400..437
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           81 a          156 c          130 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcgctc tcgggacgtc tccaccatgg cttgggctct
       61 ggtcctcctc accctcctca ctcagggctc aggatcctgg gctcagtctg ccctgactca
      121 gcctccctca gtgtccaagt ctcttggaca gtcggtcacc atctcctgca ctggaacccg
      181 cagtgacatt ggtggttata acggtgtctc ctggtaccag cagcactcag gcacagcccc
      241 cagactcctg atttatgagg tcactaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgag catctctggg ctccaggctg aggatgaggc
      361 tgattattac tgcggctcat atggcagtgg aagcactcat ggcttattcg gaggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001345             495 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:2426:10303
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001345
VERSION     KCVO01001345.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 495)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:2426:10303"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    124..457
                     /note="immunoglobulin light chain variable region"
     V_region        124..457
     V_segment       124..415
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>429
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73374.1"
                     /translation="NYYCLSYDTSLSGHGLF"
     J_segment       420..457
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        458..>495
                     /gene="IGLC"
BASE COUNT           96 a          164 c          126 g          109 t
ORIGIN      
        1 acatgggggg gggaagctct gcttcagctg tgggcacagg aggcagcact caggacagtc
       61 tccaacatgg cctcgtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg
      121 gcccagtctg tgctgacaca gccaccctca ctgtctgggg ccccagggca gagggtcacc
      181 atctcgtgca ctgggagcag ctccaacatt ggcacttatt ctgtatcctg gtgccagaag
      241 ttcccagaaa cgacccccaa cctcctcgac tatcaagata ataagcgacc ctcaggggtt
      301 tctgaccgat tctctgggtc caagtctggt ccctcagcct ccctgaccat cactgggctc
      361 cagactgagg atgggactaa ttattactgc ctgtcgtatg acaccagcct gagtggtcat
      421 ggcttattcg gaggaggaac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg
      481 gtcactctct tcccg
//
LOCUS       KCVO01001346             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:11739:15353
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001346
VERSION     KCVO01001346.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:11739:15353"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..441
                     /note="immunoglobulin light chain variable region"
     V_region        111..441
     V_segment       111..404
                     /gene="IGLV8-111"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73375.1"
                     /translation="DYYCAVYMGSGIDVF"
     J_segment       405..441
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           91 a          149 c          125 g          114 t
ORIGIN      
        1 acatggggag ctgagaagcc tgagagcact tggccttcat aagtgtcccc accatggcct
       61 ggatgatgct tctcctcgga ctccttgctt atggctcagg agtggattct gagactgtgg
      121 tgacccagga gccatcgttg tcagtgtccc ctggaggaac agtcacactc acctgtggcc
      181 tgagctctgg ctcagtctct accgataact accccagctg gtaccagcag accccaggcc
      241 aggctccacg catgctcctc ttcaacacaa acactcgccc ttctggggtc cctactcgct
      301 tctctggctc catccttggg aacaaagctg ccctcaccgt cacgggggct caggcagacg
      361 atgaatctga ttattactgt gcggtgtaca tgggtagtgg cattgatgtg ttcggaagtg
      421 gcaccaagtt gaccgtcctc ggtcagccca aggcttcccc cttggtcact ctgttcccg
//
LOCUS       KCVO01001347             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:9286:4482
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001347
VERSION     KCVO01001347.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:9286:4482"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..427
                     /note="immunoglobulin light chain variable region"
     V_region        107..427
     V_segment       107..387
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73376.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       390..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          141 c          142 g           96 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgctcactgc acagactctg tggtcaccta tgaattgact
      121 cagccacgct cagtgtccgt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 agcattggaa gtagaagtgt gcagtggtac cagcagaagc caccgcaggc ccttgtgctg
      241 gtcatctttg ctgatagcga acggccctca gggatccctg agcgattctc tggctccaat
      301 ttagggaaca ccgccaccct gaccatcagc ggcgtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag tagtagtgat gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001348             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:18825:9454
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001348
VERSION     KCVO01001348.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18825:9454"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73377.1"
                     /translation="DYYCSSYTDISTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           80 a          157 c          125 g          111 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggagcca
      181 gcagtgacat tggtggttat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcgt gatttctgac gtcagtgatc ggccctctgg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctcg tacacagaca ttagcacttg ggttttcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001349             334 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:17252:18160
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001349
VERSION     KCVO01001349.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 334)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:17252:18160"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    164..296
                     /note="immunoglobulin light chain variable region"
     V_region        164..296
     V_segment       164..260
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>268
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73378.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       261..296
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        297..>334
                     /gene="IGLC"
BASE COUNT           56 a          119 c           86 g           73 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttccaagt ctggcaacac
      181 ggcctccctg atcatctctg ggctccaggc tgaggacgag gctgattatt actgcagctc
      241 atacacaagc actaccactt ggctattcgg cggagggacc cgcctgaccg tcctaggtca
      301 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001350             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:12395:5515
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001350
VERSION     KCVO01001350.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:12395:5515"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..435
                     /note="immunoglobulin light chain variable region"
     V_region        90..435
     V_segment       90..399
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73379.1"
                     /translation="DYYCVIWHNNVWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           88 a          153 c          121 g          111 t
ORIGIN      
        1 acatgggggc ggggaaagag gctgtgtcca ccatggcctg gactcctctc ctcctcctgc
       61 tcctctctca ctgcacaggt tccctctcgc agcctgtgct gactcagcca ccctccctct
      121 cagcatctcc tggagcatca gccagactca cctgcacctt gcgcagtggc atcagtgttg
      181 gtagttacag ggtattctgg taccagcaga agccagggag tcctccccgg tatcttctga
      241 acttccacac agactcagat aagcaccagg gatctggagt ccccagccgc ttctctggat
      301 ccaaagatgc ttcggccaat gcagggattt tactcatctc tgggctccag tctgaggatg
      361 aggccgacta ttactgtgtg atttggcaca acaatgtttg ggtattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001351             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:18555:12111
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001351
VERSION     KCVO01001351.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:18555:12111"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73380.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       399..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          147 c          133 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gaactgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaga taaatatcta cactggtacc accagaagcc agcgcaggcc cctgtgctgg
      241 tcatctacta tgatagtgac cggccctcat ggatccctga gcgattctct gggtccaagt
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt aataatgatc atatcttttt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001352             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:13216:11145
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001352
VERSION     KCVO01001352.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13216:11145"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73381.1"
                     /translation="DYYCYSTDSSGNHIF"
     J_segment       388..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           94 a          145 c          119 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgacgac agtaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gatagcagtg gtaatcacat cttcgctact gggacccggc tcaccgtcct
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01001353             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:10932:7002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001353
VERSION     KCVO01001353.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:10932:7002"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73382.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          145 c          124 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgacgac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcattggggc ccaggtggag gatgaagctg actaccactg
      361 tttctcaaca gatagcagtg gtaatcatag gggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagt ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001354             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:26601:8996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001354
VERSION     KCVO01001354.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:26601:8996"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73383.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          156 c          120 g          113 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtacttata actatgtctc ctggtaccaa cagcatccag gcacagcccc
      241 caaactcatg atttttgagg tcagtgagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgttgctcat atgcagacac ctacactttt gtgtttggag gtggcaccag
      421 attgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01001355             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:22964:14210
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001355
VERSION     KCVO01001355.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:22964:14210"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73384.1"
                     /translation="DYYCQVWDSRTDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          145 c          138 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctcactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggaggca
      181 atgttggaag tgaatatgtc cactggtatc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatctatta taatactgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgccaggt gtgggacagt aggactgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001356             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:11817:12222
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001356
VERSION     KCVO01001356.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11817:12222"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..427
                     /note="immunoglobulin light chain variable region"
     V_region        107..427
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73385.1"
                     /translation="DYFCSSYTGSSTWVF"
     J_segment       402..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>475
                     /gene="IGLC"
BASE COUNT           83 a          155 c          125 g          112 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtaa tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gttcatctct gggctcctgg ctgaggacga
      361 ggctgattat ttctgcagct catacacagg cagtagcact tgggtattcg gcggagggac
      421 ccggctggac gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001357             366 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:15786:20022
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001357
VERSION     KCVO01001357.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 366)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:15786:20022"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..328
                     /note="immunoglobulin light chain variable region"
     V_region        6..328
     V_segment       6..291
                     /gene="IGLV8-111"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <256..>300
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73386.1"
                     /translation="DYYCSLYMATGFVFF"
     J_segment       292..328
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        329..>366
                     /gene="IGLC"
BASE COUNT           68 a          123 c           92 g           83 t
ORIGIN      
        1 acatggggga cccaggagcc atcgttgtca gtgtcccctg gaggaacagt cacactcacc
       61 tgtggcctga actctggctc agtctctatc agtaattacc ccagctggta ccagcagacc
      121 ccaggccagg ctccacgcat gctcatcttc agcacaaaca gtcgcccttc tggggtccct
      181 gatcgcttct ctggctccat ccgtgggaac aaagctgccc tcaccatcac gggggctcag
      241 gcagacgatg actctgatta ttactgttcg ctctacatgg ctactggctt tgtgttcttc
      301 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      361 ttcccg
//
LOCUS       KCVO01001358             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:17285:10217
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001358
VERSION     KCVO01001358.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17285:10217"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73387.1"
                     /translation="DYYCHFYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          163 c          120 g          111 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agtagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca atcagctgcg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcact tctatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001359             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:21892:12861
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001359
VERSION     KCVO01001359.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:21892:12861"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73388.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          144 c          125 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctctgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gaaatgcatt
      181 gccaaaatac tatgcttatt ggttccagca gaagccaggc cagtcccctg tggcgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtagag gatgaggctg actactactg
      361 ttactcaaca gatagcagtg gtactaatgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001360             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:18736:16054
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001360
VERSION     KCVO01001360.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:18736:16054"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73389.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           84 a          157 c          121 g          113 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtactt ataactatgt ctcctggtac caacagcatc caggcacagc
      241 ccccaaactc atgatttttg aggtcagtga gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgttgct catatgcaga cacctacaca tttgtgtttg gaggtggcac
      421 cagattgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001361             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:9185:7505
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001361
VERSION     KCVO01001361.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9185:7505"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73390.1"
                     /translation="DYYCYSTDSSGTHIF"
     J_segment       388..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          147 c          118 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgacgac agtaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gatagcagtg gtactcacat cttcgctcct gggacccggc tcaccgtcct
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01001362             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:16925:16339
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001362
VERSION     KCVO01001362.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16925:16339"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73391.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           89 a          140 c          118 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gggagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gtagtggtaa ttatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001363             490 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:19877:4104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001363
VERSION     KCVO01001363.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 490)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19877:4104"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..445
                     /note="immunoglobulin light chain variable region"
     V_region        122..445
     V_segment       122..417
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <380..>424
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73392.1"
                     /translation="DYFCCSYADTYTFVF"
     J_segment       422..445
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>490
                     /gene="IGLC"
BASE COUNT           89 a          160 c          127 g          114 t
ORIGIN      
        1 acatgggcaa cgcagagtac atgggggggg tctcagacgg cagcgctctc gggacatctc
       61 caccatggcc tgggctctgc tcctcctcac cctcctcact cagggcacag gatcctgggc
      121 tcaggctgcc ctgactcagc ctcgctcagt gtctgggtct cctggacagt cggtcaccat
      181 ctcctgcact ggaaccagca gtgacatcgg tggttataac tttgtctcct ggtaccaaca
      241 acatccaggc acagccccca aactcatgat ttatgaggtc aatcagcggc cctcaggggt
      301 ctctgatcgc ttctctggct caaagtctgg caacacggcc tccctgaccg tctccggggt
      361 ccaggctgag gacgaggctg attatttctg ctgctcatat gcagacacct acacttttgt
      421 tttcggaagt ggcaccaggt tgaccgtcgt cggtcagccc aaggcttccc ccttggtcac
      481 tctgttcccg
//
LOCUS       KCVO01001364             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:10497:14894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001364
VERSION     KCVO01001364.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:10497:14894"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..439
                     /note="immunoglobulin light chain variable region"
     V_region        94..439
     V_segment       94..403
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73393.1"
                     /translation="DYYCVIWHNNVWVF"
     J_segment       404..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           89 a          154 c          122 g          112 t
ORIGIN      
        1 acatggggga ctgcggggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcgcagcctg tgctgactca gccaccctcc
      121 ctctcagcat ctcctggagc atcagccaga ctcacctgca ccttgcgcag tggcatcagt
      181 gttggtagtt acagggtatt ctggtaccag cagaagccag ggagtcctcc ccggtatctt
      241 ctgaacttcc acacagactc agataagcac cagggatctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcggc caatgcaggg attttactca tctctgggct ccagtctgag
      361 gatgaggccg actattactg tgtgatttgg cacaacaatg tttgggtatt cggcggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001365             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:7926:8441
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001365
VERSION     KCVO01001365.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7926:8441"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73394.1"
                     /translation="DYYCSSYTSSSSWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          154 c          124 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagcagttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001366             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:22283:20115
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001366
VERSION     KCVO01001366.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:22283:20115"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..447
                     /note="immunoglobulin light chain variable region"
     V_region        119..447
     V_segment       119..407
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73395.1"
                     /translation="DYYCQSFDSSLNTVLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>487
                     /gene="IGLC"
BASE COUNT           91 a          161 c          127 g          108 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcactgtc tggggcgccc gggcagaggg tcaccatctc
      181 ctgcactggg agcaccgcca acattggggc ttattatgtg cagtggtacc agcagcttcc
      241 aggaacggcc cccaaactcc tcatctatga aaataataag cgaccctcag gggtctctga
      301 tcgattctct ggctcccagt ctggaacctc tgcctccctg accatcactg gactccagtc
      361 tgaggatgag ggtgattatt actgccagtc ctttgacagc agcctgaata ccgtgttatt
      421 cggaggaggg acccggctga ccgtcctgag tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCVO01001367             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:16699:6529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001367
VERSION     KCVO01001367.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16699:6529"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..425
                     /note="immunoglobulin light chain variable region"
     V_region        105..425
     V_segment       105..385
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73396.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       388..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           85 a          141 c          141 g           96 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactgcac agactctgtg gtcacctatg aattgactca
      121 gccacgctca gtgtccgtgt ccccaggaca gacggccagg atcacctgtg ggggagacag
      181 cattggaagt agaagtgtgc agtggtacca gcagaagcca ccgcaggccc ttgtgctggt
      241 catctttgct gatagcgaac ggccctcagg gatccctgag cgattctctg gctccaattt
      301 agggaacacc gccaccctga ccatcagcgg cgtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta gtagtgatgt gttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001368             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:10158:4282
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001368
VERSION     KCVO01001368.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10158:4282"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73397.1"
                     /translation="DYYCCSYAGRFTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          156 c          123 g          111 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctgggaccag
      181 cagtgacatc ggtggttata actttgtctc ctggtaccaa cagcatgcag gcacagcccc
      241 caaactcatg atttatgagg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtcc ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgacac
      361 tgattattac tgctgctcat atgcaggcag gttcactttt gtgttcggaa gtggcaccaa
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01001369             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:26710:8002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001369
VERSION     KCVO01001369.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:26710:8002"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..444
                     /note="immunoglobulin light chain variable region"
     V_region        111..444
     V_segment       111..404
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73398.1"
                     /translation="DYYCSLWDSRLSSRVF"
     J_segment       409..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          154 c          127 g          109 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctct ccttctcact ctgctggttc actgcacagg gtcctgggcc cagtctgtgc
      121 tgacgcagcc gccctcagca tctggggccc ccgggcagag ggtcaccatc tcctgcactg
      181 ggaccagctc caacatcggg gcgaattatt atgtttcctg gtaccagcag ttcccaggaa
      241 cagcccccaa actcctcatc tatgaaaata ataagcgacc ctcaggggtt tctgaccgat
      301 tctctggctc caagtctggt acctcagcct ccctgaccat ctctggactc caatctgagg
      361 atgaggctga ttattattgc tcactatggg atagcaggct gagtagtcgg gtattcggcg
      421 gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001370             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:17587:16143
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001370
VERSION     KCVO01001370.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:17587:16143"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73399.1"
                     /translation="DYYCQVWDSTSDHPIF"
     J_segment       395..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           81 a          147 c          136 g          103 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagtctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac ggacggccag gatcacgtgt gggggagaca
      181 tcgttggaag tgaatatgtt cactggtatc agcagaagtc agcgcaggcc cctgttgtgg
      241 tcatctatta ttattctgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggagcac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactact
      361 actgtcaggt gtgggacagt actagtgatc atcccatctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01001371             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:5878:17401
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001371
VERSION     KCVO01001371.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:5878:17401"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73400.1"
                     /translation="DYYCYSTDNSDNHRGFF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           95 a          142 c          124 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgacc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg tattgatcat
      241 gtatgaggac accaagcggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actattactg
      361 ttactcaaca gataacagtg ataatcatag gggctttttc ggagggggga cccgactgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001372             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:14423:15894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001372
VERSION     KCVO01001372.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:14423:15894"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73401.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       390..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           86 a          142 c          137 g           96 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactgcacag actctgtggt ctcctatgaa ctgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacagca
      181 ttggaagtag aagtgtgcag tggtaccagc agaagccacc gcaggccctt ctactggtca
      241 tctatgctga tagcgaacgg ccctcaggga tccctgagcg attctctggc tccaatttag
      301 ggaacaccgc caccctgacc atcagcggcg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatgttt tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001373             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:16707:6205
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001373
VERSION     KCVO01001373.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16707:6205"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73402.1"
                     /translation="DYYCYSSDSGADYWVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           89 a          140 c          129 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggtt ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttattcatca gatagcggtg ctgattattg ggtgttcggc ggagggaccc ggctgaccgt
      421 cccaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001374             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:14630:9797
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001374
VERSION     KCVO01001374.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14630:9797"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73403.1"
                     /translation="DYYCSSYGSSSTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           88 a          152 c          125 g          108 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccccgactc
      121 agtttccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtaatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggat gaggacgagg
      361 ctgattatta ctgcagctca tatggaagca gtagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001375             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:19410:6290
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001375
VERSION     KCVO01001375.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:19410:6290"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..409
                     /note="immunoglobulin light chain variable region"
     V_region        88..409
     V_segment       88..375
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73404.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       376..409
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           91 a          139 c          116 g          101 t
ORIGIN      
        1 tcaggaggcc acagctctgg gtgtctcacc atggcctgga ttcctctcct actccccctc
       61 ctcactttct gcacaggctc tgcagcctcc tatgagctga cacagcaacc ttcggtgtca
      121 gtgtctccag gacagacggc caggatcacc tgctctggag atgcattgcc agaaaaatat
      181 gcttattggt tccagcagaa gccaggccag tcccctgtgt tgatcatcaa tgaggacagc
      241 aaacggccct ctgggatccc tgagagattc tctggctcca gctcagggac agtggccacc
      301 ttgactctca gtggggccca ggtggaggat gaagctgact actattgttc ctcaacagat
      361 agcagtggta atcatgtatt cggcggaggg acccggctga ccgtcctagg tcagcccaag
      421 gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001376             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:8808:22412
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001376
VERSION     KCVO01001376.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8808:22412"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73405.1"
                     /translation="DYYCTSYAGSNTYIF"
     J_segment       402..437
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          161 c          117 g          110 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcaggac gtctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtgctt ataactatgt ctcctggtac caacaccacc caggcaaagc
      241 ccccaaactc atgatttatg atgtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaaa tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggatga
      361 ggctgattat tattgtacct catatgcagg cagcaacact tacatcttcg gtgctgggac
      421 ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCVO01001377             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:15278:18285
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001377
VERSION     KCVO01001377.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:15278:18285"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..409
                     /note="immunoglobulin light chain variable region"
     V_region        87..409
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73406.1"
                     /translation="DYYCYSSDISGNHRVF"
     J_segment       376..409
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>449
                     /gene="IGLC"
BASE COUNT           92 a          137 c          116 g          104 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaagacagta
      241 aacggccctc tgggatccct gagagattct ctggctccac ttcagggaca gtggccacct
      301 tgactattag tggggcccag gtggaggatg aagctgacta ctactgttac tcatcagata
      361 tcagtgggaa tcatagggta ttcggcggag ggacccggct gaccgtcctt ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001378             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:15558:23146
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001378
VERSION     KCVO01001378.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:15558:23146"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73407.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          156 c          127 g          111 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc aatgtctggg gcgcccgggc agggggtcac catctcctgc
      181 actgggagca gctccaatat tggagattat tatgtgcagt ggtaccagca gtttccagga
      241 acggccccca gactcctcat ctatgaaaat aataaacgac cctcaggggt ttctgctcga
      301 ttctctggct cccagtctgg tacctcagcc tccctgacca tcactggact ccagtctgag
      361 gatgaggctg attattactg ccagtcctat gacagcagcc tgagtgccgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01001379             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:13059:7492
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001379
VERSION     KCVO01001379.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13059:7492"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73408.1"
                     /translation="DYYCHLYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          162 c          123 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcact tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001380             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:14153:8763
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001380
VERSION     KCVO01001380.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14153:8763"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73409.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       407..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           95 a          159 c          120 g          107 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcctcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcacc tccaacatcg gaactaatag tgtatcctgg taccagcagc tcccagaaac
      241 ggctcccaaa ctcctcatct attataatga tcgacgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggca cgtcagcctc cctggccatc agtgggctcc agaccgagga
      361 tgaggctgat tattactgcg cagcatggga taacagcctg agcggttaca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCVO01001381             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:7364:12447
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001381
VERSION     KCVO01001381.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:7364:12447"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..433
                     /note="immunoglobulin light chain variable region"
     V_region        109..433
     V_segment       109..396
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73410.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       401..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           90 a          145 c          140 g           96 t
ORIGIN      
        1 acatgggggc ccagcctggc ctcgggaagc agccttggcg gtgcctcagc catggccggg
       61 acccttctcc tcctcggcct ccttgcttac tgcacagact ctgcggtctc ctatgacctg
      121 actcagccac cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgtggggga
      181 gacaatgttg gaagtgaata tgtgcactgg taccaacaga aaccagcgca ggcccctgtg
      241 gtggtcatcc attataatag tgaccggccc tcagggatcc ctgagcgatt ctctggctcc
      301 aaatcaggga acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac
      361 tattactgtc aggtgtggga cagtagtagt gatcattgtg tattgggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001382             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:21314:11693
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001382
VERSION     KCVO01001382.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:21314:11693"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73411.1"
                     /translation="DYFCCSYADTYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           82 a          157 c          121 g          115 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtactt ataactatgt ctcctggtac caacagcatc caggcacagc
      241 ccccaaactc atgatttttg aggtcagtga gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat ttctgttgct catatgcaga cacctacact tttgtgtttg gaggtggcac
      421 cagattgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001383             364 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:25701:10165
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001383
VERSION     KCVO01001383.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 364)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:25701:10165"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    3..326
                     /note="immunoglobulin light chain variable region"
     V_region        3..326
     V_segment       3..286
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <248..>298
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73412.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       290..326
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        327..>364
                     /gene="IGLC"
BASE COUNT           79 a          107 c           99 g           79 t
ORIGIN      
        1 acatgggctg acacagcctc cctcggtgtc agtgtcccca ggacagacgg ccaggatctc
       61 ctgctctgga gatgcattgc caaaaaaatt tgcttcttgg ttccagcaga aggcaggcca
      121 gtcccctgtg ctgatcatct atgaggacag caaacggccc tctgggatcc ctgagagatt
      181 ctctggctcc agttcaggga caatggccac cttgactatc agtggggccc aggtggagga
      241 tgaagctgac tactactgtt actcaacaga taacagtgat actcataggg gcttcttcgg
      301 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      361 cccg
//
LOCUS       KCVO01001384             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:20772:6550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001384
VERSION     KCVO01001384.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20772:6550"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73413.1"
                     /translation="DYYCQVWDITTDHDVF"
     J_segment       389..425
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           94 a          138 c          129 g          102 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatgacct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ttctgcggcc tcctatgagc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaaa aatgtgcact ggcaccagca gaagccaccg caggcccctg ttttggtcat
      241 ctattatgat atcgaacggc cctcagggat ccctgagcga ttctctggcg ccaaatcagg
      301 gaacaccgcc accctgatca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattacta ctgatcatga tgtattcgga agtggcacca agttgaccgt
      421 cctcggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01001385             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:17084:2892
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001385
VERSION     KCVO01001385.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17084:2892"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73414.1"
                     /translation="DYYCHSLDTSGNDVF"
     J_segment       378..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           87 a          141 c          117 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttactggtt ccagcagaag ccaggccagt cccctgtggt gatcatctat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctactgtcat tcattagata
      361 ccagtggtaa tgatgttttc ggcgggggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001386             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:3851:11297
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001386
VERSION     KCVO01001386.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:3851:11297"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73415.1"
                     /translation="DYYCQVWDSSTDHRVF"
     J_segment       394..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          149 c          140 g           91 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctgactc
      121 agccaccctc gctgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaag taaatatgtg cactggtacc agcagaagcc aacgcaggcc cctgtggtgg
      241 tcatcgatta tgatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactact
      361 actgtcaggt gtgggacagt agtactgatc atcgggtatt cggcggaggg acccggctga
      421 ccgccctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001387             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:13958:15915
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001387
VERSION     KCVO01001387.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13958:15915"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73416.1"
                     /translation="DYYCSSRDSSGNYVF"
     J_segment       390..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           91 a          141 c          128 g          101 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccagaaaa atttgcttat tggttccaac agaagccagg ccagtcccct gtgctgatca
      241 tcaatgagga cagcaagcgg ccctctggga tccctgagag attctctggc tccagctcag
      301 ggacagtggc caccttgact ctcagtgggg cccaggtgga ggatgaaggt gactactact
      361 gttcctcaag agatagcagt ggtaattatg tattcggcgg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001388             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:13166:18988
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001388
VERSION     KCVO01001388.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:13166:18988"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73417.1"
                     /translation="DYYCYSTDTSGHGLF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           92 a          140 c          122 g          106 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgtttatt ggttccagca gaagccaggc cagtcccctg tactgatcat
      241 ctatgaggac tttaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactt tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gatactagtg gtcatggcct atttggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001389             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:13053:10111
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001389
VERSION     KCVO01001389.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:13053:10111"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73418.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          160 c          119 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001390             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:18817:10720
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001390
VERSION     KCVO01001390.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18817:10720"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73419.1"
                     /translation="DYYCYSTDNSGNQSIF"
     J_segment       377..408
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>449
                     /gene="IGLC"
BASE COUNT           93 a          141 c          115 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acaaccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctgggga tgcattgcca aaaaaatttg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtggt gatcatctat gaggacagta
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcac tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagata
      361 acagtggtaa tcagagcatc ttcggtgctg ggacccggct caccgtccga ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001391             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:16607:15502
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001391
VERSION     KCVO01001391.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:16607:15502"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73420.1"
                     /translation="DFYCSSTDSSGNHVF"
     J_segment       378..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           87 a          142 c          117 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctccgggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgactt ctactgttcc tcaacagata
      361 gtagtggtaa tcatgtcttc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001392             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:8359:6345
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001392
VERSION     KCVO01001392.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:8359:6345"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73421.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       391..423
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          141 c          124 g          103 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 caaaaaagta tgcttattgg ttccagcaga agccaggcca gtcccctgtg ttgatcatct
      241 atgaagacga caaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc agtggggccc aggtggagga tgaaggtgac tactactgtt
      361 actcaataga cagtagtggt agtcatagcg tcttcggtgc tgggacccgg ctcaccgtcc
      421 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCVO01001393             527 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:13245:11698
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001393
VERSION     KCVO01001393.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 527)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 527)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..527
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:13245:11698"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    162..489
                     /note="immunoglobulin light chain variable region"
     V_region        162..489
     V_segment       162..454
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <420..>461
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73422.1"
                     /translation="DYYCFVYYSGTQFF"
     J_segment       459..489
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        490..>527
                     /gene="IGLC"
BASE COUNT          120 a          174 c          127 g          106 t
ORIGIN      
        1 acatggggac cccctccaag cagagagctc aataggagat aaagagccat cagaatccag
       61 ccccagctct ggagccagag atcccttcca ataccagcac catggcctgg actctgctcc
      121 tcctccagtt cctcctcact tgctgcccag ggtccaattc tcaggctgta gtgactcagg
      181 agccctcaat gactgtgtcc ccaggaggga cagtcactct cacctgtggc tccagcactg
      241 gagcagtcac cagtggtaac tttccaaact ggttccagca gaaacctgga caagtcccca
      301 ggggactgat ttacaataca aacaacaaac actcctggac ccctgcccgg ttctcaggct
      361 ccctcgctgg gggcaaagct gccctgacac tgtcaggagc acagcccgag gacgaggctg
      421 attattactg cttcgtgtac tatagtggta ctcaattctt cggaggaggg acccggctga
      481 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001394             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:22736:3066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001394
VERSION     KCVO01001394.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22736:3066"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73423.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          151 c          124 g          114 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttttg agtgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcttg atttatgagg tcagttatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct gccaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattat tgcagctcat acacaagtag tagtacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001395             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:25570:10990
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001395
VERSION     KCVO01001395.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:25570:10990"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73424.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           97 a          144 c          122 g           97 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggtaccagca gaaaccaggc cagtccccta tgctgatcat
      241 ctgtgaggac agcaaacggc cctctgggat ccctgaaaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacaacagtg gtcagggctc attcggagga gggacccagc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001396             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:13190:15249
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001396
VERSION     KCVO01001396.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:13190:15249"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..433
                     /note="immunoglobulin light chain variable region"
     V_region        100..433
     V_segment       100..393
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73425.1"
                     /translation="DYYCLSYDSSLSAHYIF"
     J_segment       396..433
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           95 a          161 c          112 g          103 t
ORIGIN      
        1 acatgggggg cacaggaggc agcactcagg acagtctcca gcatggcctc gtctcctctc
       61 ctcctcaccc ttctcattca ctgcacaggg tcctgggccc agtctgtgct gacacagcca
      121 ccctcagtgt ctggggcccc agggcagagg gtcaccatct cgtgcactgg gagcagctcc
      181 aacattggag gtgattatgt atcctggtac caacagctcc caggaacaac ccccaaactc
      241 ctcatctatc aaaataataa gcgaccctca ggggtttctg accgattctc tggctccaag
      301 tctggtacct cagcctccct gaccatcact gggctccaga ctgaggatga ggctgattac
      361 tactgcctgt cctatgacag cagcctgagt gctcattaca tcttcggtcc tgggacccgg
      421 ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCVO01001397             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:10988:18290
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001397
VERSION     KCVO01001397.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10988:18290"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73426.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          144 c          126 g          101 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctctgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggaaatgcat
      181 tgccagaata ctatgcttat tggttccagc agaagccagg ccagtcccct gtggcgatca
      241 tctatgagga caacaaacgg ccctctggga tccctgagag attctctggc tccagctcag
      301 ggacagtggc caccttgact atcagtgggg cccaggtaga ggatgaggct gactactact
      361 gttactcaac agatagcagt ggtactaatg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001398             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:8649:11915
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001398
VERSION     KCVO01001398.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8649:11915"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..416
                     /note="immunoglobulin light chain variable region"
     V_region        92..416
     V_segment       92..378
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73427.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       384..416
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           99 a          135 c          118 g          102 t
ORIGIN      
        1 acatgggagg aggcagagct ctgggtgtct caccatggcc tggattcctc tcctactccc
       61 cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc caccctcggt
      121 gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat tgccaaaaaa
      181 atatgtatat tggttccagc agaagccagg ccagtcccct gtgttgatca tctatgagga
      241 caacaaacgg ccctctggga ttcctgagag attctctggc tccagctcag ggacagtggc
      301 caccttgact atcagtgggg cccaggtgga ggatgaaggt gactactact gttactcaag
      361 agatagtagt gaaaatcaaa gtgtcttcgg tgctgggacc cggctcaccg tcctaggtca
      421 gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCVO01001399             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:8277:9040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001399
VERSION     KCVO01001399.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:8277:9040"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73428.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       392..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          141 c          138 g           96 t
ORIGIN      
        1 acatgggggg gcctcgggaa gcagccttgg cggtgcctca gccatggccg ggacccttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggtc tcctatgaac tcactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gaggcaatgt
      181 tggaagtgaa tatgtccact ggtatcaaca gaagccaccg caggcccctg tggtggtcat
      241 ctattataat actgaccggc cctcagggat ccctgagcga ttctctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagga gtgatcatag tttattggga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001400             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:16051:18440
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001400
VERSION     KCVO01001400.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16051:18440"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..445
                     /note="immunoglobulin light chain variable region"
     V_region        121..445
     V_segment       121..407
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73429.1"
                     /translation="DFYCYSRDSSENQSVF"
     J_segment       413..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT          101 a          144 c          130 g          108 t
ORIGIN      
        1 acatggggct agggagccca gctgtgctgt gggctcagga ggcagagctc tgggtgtctc
       61 accatggcct ggattcctct cctactcccc ctcctcactt tctgcacagg ctctgcagcc
      121 tcctatgagc tgacacagcc accctcggtg tcagtgtccc caggacagac ggccaggatc
      181 acctgctctg gagatgcatt gccaaaaaaa tatgtatatt ggttccagca gaagccaggc
      241 cagtcccctg tgttgatcat ctatgaggac aacaaacggc cctctgggat tcctgagaga
      301 ttctctggct ccagctcagg gacagtggcc accttgacta tcagtggggc ccaggtggag
      361 gatgaaggtg acttctactg ttactcaaga gatagtagtg aaaatcaaag cgtcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCVO01001401             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:8654:5446
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001401
VERSION     KCVO01001401.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8654:5446"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73430.1"
                     /translation="DYYCSSTDFSGNHVF"
     J_segment       390..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           92 a          145 c          123 g          101 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccagaaaa atatgcttat tggttccaac agaagccagg ccagtcccct gtgctgatca
      241 tcaatgagga caccaaacgg ccctctggga tccctgagag attctctggc tccagctcag
      301 ggacagtggc caccttgact ctcagtgggg cccaggtgga ggatgaagct gactactact
      361 gttcctcaac agatttcagt ggtaatcatg tattcggcgg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001402             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:17660:20673
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001402
VERSION     KCVO01001402.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:17660:20673"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73431.1"
                     /translation="DYYCYSSESSADYWVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>449
                     /gene="IGLC"
BASE COUNT           90 a          140 c          117 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gacgacacca
      241 aacggccctc tgggatccct gagagattct ctggttccag ctcagggaca gtggccacct
      301 tgactatcag tgggacccag gtggaggatg aagctgacta ctactgttac tcatcagaaa
      361 gtagtgctga ttattgggtg ttcggcggag ggacccggct gaccgtccca ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001403             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:4926:17669
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001403
VERSION     KCVO01001403.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:4926:17669"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73432.1"
                     /translation="DYYCQVWDISSDHDVF"
     J_segment       389..425
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           90 a          137 c          135 g          101 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatgacct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ttctgcggcc tcctatgagc tgactcagcc
      121 accctcggtg tcactgtccc caggacagac ggccaggatc gcctgtgggg gagacaacct
      181 tggaagtaag aatgtgcact ggtaccagca gaagccaccg caggcccctg tattggtcat
      241 ctattatgat agcgaacggc cctcagggat ccctgagcga ttctctggcg ccaaatcagg
      301 gaacaccgcc accctggtca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattagta gtgatcatga tgtgttcgga agtggcacca agttgaccgt
      421 cctcggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01001404             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:15363:9834
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001404
VERSION     KCVO01001404.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:15363:9834"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..444
                     /note="immunoglobulin light chain variable region"
     V_region        115..444
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73433.1"
                     /translation="DYYCATWDNSLSGVLF"
     J_segment       409..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>483
                     /gene="IGLC"
BASE COUNT           97 a          153 c          124 g          109 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca gctccaatat cggaagtaat agtgtatcct ggtaccagca actcccagaa
      241 acggctccca aactcctcat ttattataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcactgggct ccagaccgag
      361 gatgaggctg attattactg cgcaacatgg gataatagcc tgagcggtgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaagtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01001405             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:19597:10522
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001405
VERSION     KCVO01001405.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19597:10522"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73434.1"
                     /translation="HYYCCSYADTYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           78 a          162 c          121 g          114 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc ttggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggcac
      181 cagcagtgac atcggtggtt ataactttgt ctcctggtac caacaccatc caggcacagc
      241 ccccaaactc gtgatttatg aggtcactca gcggccctcg ggggtctctg atcgcttctc
      301 tggctccaag tctggcaacg cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctcattat tactgctgct catatgcaga cacttacact tttgtgttcg gaggtggcac
      421 caagttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001406             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:13024:5197
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001406
VERSION     KCVO01001406.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13024:5197"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73435.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           85 a          160 c          118 g          110 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtagttat aaccgtgtct cctggtacca actacaccca ggcaaagccc
      241 ccaaactcat gatttttgac gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacgcaagca ctaccacttg gctattcggc ggagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001407             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:22626:19012
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001407
VERSION     KCVO01001407.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22626:19012"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73436.1"
                     /translation="DYYCQVWDSSSAVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          140 c          139 g           99 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gagttgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggataca
      181 tcattggaag taaaagtgtg cagtggtacc agcagaagcc accgcaggcc cttgtgctgg
      241 tcatctatgc tgataacaaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggatgac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgctg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001408             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:18613:12329
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001408
VERSION     KCVO01001408.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:18613:12329"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73437.1"
                     /translation="EYYCSSYADIYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          161 c          118 g          108 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg cctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca cgggcaccag
      181 cagtgacatc ggtggttaca actttgtctc ctggtaccaa caccatccag acacagcccc
      241 caaactcgtg atttatgagg tcactcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgaatattac tgcagttcat atgcagacat ctacacattt gtgttcggaa gtggcaccaa
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01001409             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:11120:20578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001409
VERSION     KCVO01001409.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:11120:20578"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..430
                     /note="immunoglobulin light chain variable region"
     V_region        104..430
     V_segment       104..396
                     /gene="IGLV10-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73438.1"
                     /translation="DYYCSAWDSSLSAVVF"
     J_segment       402..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>472
                     /gene="IGLC"
BASE COUNT          104 a          160 c          126 g           82 t
ORIGIN      
        1 acatggggaa agcagagctt cggcaagcac agtgggaatc cgcaccatgc cctgggctct
       61 gctcctcctg accctcctca ctcactctgc agtgccagtg gtccaggcag ggctgactca
      121 gccaccctca gtgtccaagg ccttgagaca gacggccaca ctcacctgca ctggaaacag
      181 caacaatgtt ggcaaccagg gagcaggttg gctgcagcag caccagggcc accctcccaa
      241 actgctgtcc tacaggaata acaaccggcc ctccgggatc tcagagagat tctctgcatc
      301 caggtcagga aacacagcct ccctgaccat caccggactc caacctgagg atgaggctga
      361 ctattactgc tcagcatggg acagcagcct cagtgccgtg gtattcggag gggggacccg
      421 gctgaccgtc gttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001410             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:20302:19442
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001410
VERSION     KCVO01001410.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20302:19442"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73439.1"
                     /translation="DYYCHSLDTSGNDVF"
     J_segment       378..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           89 a          140 c          116 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttactggtt ccagcagaag ccaggccagt cccctgtggt gatcatctat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgtcat tcattagata
      361 ccagtggtaa tgatgttttc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001411             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:12786:7415
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001411
VERSION     KCVO01001411.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12786:7415"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73440.1"
                     /translation="DYYCGVWDSSLSARLF"
     J_segment       415..450
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           93 a          157 c          130 g          108 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggaccc cgggcagagg gtcaccatct
      181 cgtgcactgg gagcagctcc aacattggag gttattttgt atactggtac cagcagttcc
      241 caggaacagc ccccaaactc ctcatctatg acaataataa acgaccctca gggatttctg
      301 accgattctc tggctccaag tctggtacct cagcctcccc gaccatcact gggctccagc
      361 ctggggatga ggctgattat tactgcggag tatgggatag cagcctgagt gctcgcttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCVO01001412             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:18749:4477
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001412
VERSION     KCVO01001412.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18749:4477"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73441.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       399..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          149 c          132 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tcccccggac agacggccag gatcacctgt gggggagaca
      181 accttggaga taaatatcta cactggtacc accagaatcc agcgcaggcc cctgtgctgg
      241 tcatctacta tgatagtgac cggccctcat ggatccctga gcgattctct gggtccaagt
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt aataatgatc atatcttttt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001413             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:25828:17237
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001413
VERSION     KCVO01001413.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:25828:17237"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73442.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           92 a          140 c          116 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gagagaatct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtagaggatg aagctgacta ctactgttcc tcaacagata
      361 gtagtggtaa tcatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001414             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:14156:5772
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001414
VERSION     KCVO01001414.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:14156:5772"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73443.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           91 a          158 c          128 g          109 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcactggga gcagctccaa cattggaggt tattatgtgc agtggtacca gcagcttcca
      241 ggaacggccc ccaaactcct catatatgaa aataataagc gaccctcagg ggtttctgat
      301 cgattctctg gctcccagtc tggtacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gcctgagtgc cgtgttattc
      421 ggagcaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01001415             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:20437:6892
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001415
VERSION     KCVO01001415.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:20437:6892"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73444.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          142 c          137 g           98 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgac ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacata cggccaggat cacctgtgtg ggagacaatg
      181 ttggaagtga atatgtgcac tggtaccaac agaagccacc gcaggcccct gtggtggtca
      241 tccattataa tagtgaccgg ccctcaggga tccctgaacg attctctggc tccaaatcag
      301 ggagcgccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatcata gtttattggg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001416             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:22260:3921
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001416
VERSION     KCVO01001416.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:22260:3921"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..454
                     /note="immunoglobulin light chain variable region"
     V_region        130..454
     V_segment       130..417
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73445.1"
                     /translation="DYYCYSTISSGNDRIF"
     J_segment       421..454
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT          103 a          147 c          133 g          109 t
ORIGIN      
        1 acatggggaa gagaagccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactccccc tcctcacttt ctgcacaggc
      121 tctgcagcct cctatgagct gacacagcca ccctcggtgt cagtgtcccc aggacagacg
      181 gccaggatca cctgctctgg agatgcattg ccaaaaaaat atgtttattg gttccagcag
      241 aagccaggcc agtcccctgt gctgatcatc tatgaggaca gcaaacggcc ctctgggatc
      301 cctgagagat tctctggctc cagctcaggg acagtggcca ccttgactat cagtggggcc
      361 caggtggagg atgaagctga ctactactgt tactcaacaa ttagtagtgg taatgatagg
      421 atcttcggtg ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc
      481 actctgttcc cg
//
LOCUS       KCVO01001417             345 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:11955:18825
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001417
VERSION     KCVO01001417.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 345)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 345)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:11955:18825"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    2..307
                     /note="immunoglobulin light chain variable region"
     V_region        2..307
     V_segment       2..267
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <232..>279
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73446.1"
                     /translation="DYYCSLWDSRLSSRVF"
     J_segment       272..307
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        308..>345
                     /gene="IGLC"
BASE COUNT           72 a          106 c           88 g           79 t
ORIGIN      
        1 acatgggggg cccccgggca gagggtcacc atctcctgca ctgggaccag ctccaacatt
       61 ggggcgaatt attatgtttc ctggtaccag cagttcccag gaacagcccc caaactcctc
      121 atctatgaaa ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      181 ggtacctcag cctccctgac catctctgga ctccaatctg aggatgaggc tgattattat
      241 tgctcactat gggatagcag gctgagtagt cgggtattcg gcggagggac ccgactgacc
      301 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001418             391 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:17428:12047
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001418
VERSION     KCVO01001418.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 391)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 391)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:17428:12047"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    23..353
                     /note="immunoglobulin light chain variable region"
     V_region        23..353
     V_segment       23..316
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <278..>325
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73447.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       317..353
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        354..>391
                     /gene="IGLC"
BASE COUNT           74 a          122 c          107 g           88 t
ORIGIN      
        1 acatggggca gggtcctggg cccagtctgt gctgactcag cctccctcag cgtctgaggc
       61 cgccaggaac agtgtcacca tctcctgttc tggaagcacc tccaacatcg ggagtaacag
      121 tgtgtcctgg tacctgcagc tcccagaagc ggctcccaaa ctcctcatct attataatga
      181 tcggcgagcc tcaggtgtct ctgaccgatt ctctggctcc aagtctggcc cgtcagcctc
      241 cctggccatc agtgggctcg agaccgaaga tgaggctgat tattattgcg cagtatggga
      301 tgatagcctg agcggtgtgt tattcggagg agggacccga ctgaccgtcc taggtcagcc
      361 caagactgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001419             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:15515:13285
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001419
VERSION     KCVO01001419.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:15515:13285"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73448.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           98 a          145 c          123 g           98 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccatcctc actttctgca caggctctgc agcctcctat gagctgacac
      121 agccaccctc gttgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg
      181 cattgccaga aaaatatgct tattggtacc agcagaaacc aggccagtcc cctatgctga
      241 tcatctatga ggacaacaaa cggccctctg ggatccctga aagattctct ggctccagct
      301 cagggacagt ggccaccttg actatcactg gggcccaggt ggaggatgaa gctgactact
      361 actgttactc agcagacaac agtggtcagg gctcattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001420             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:13322:4940
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001420
VERSION     KCVO01001420.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13322:4940"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..454
                     /note="immunoglobulin light chain variable region"
     V_region        130..454
     V_segment       130..417
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73449.1"
                     /translation="DYYCSSTDSRDNHRVF"
     J_segment       419..454
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT          103 a          149 c          137 g          103 t
ORIGIN      
        1 acatggggaa gagaagccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactccccc tcctcacttt ctgcacaggc
      121 tctgcagcct cctatgagct gacacagcca ccctcggtgt cagtgtcccc aggacagacg
      181 gccaggatca cctgctctgg agatgcattg ccaaaaaaat atgcttattg gttccagcag
      241 aagccaggcc agtcccctgt gctgatcatc tatgaggaca gcaaacggcc ctctgggatc
      301 cctgagagat tctctggctc cagctcaggg acagtggcca cgttgactat cagtggggcc
      361 caggtggagg atgaagctga ctactactgt tcctcaacag atagcaggga taatcatagg
      421 gtattcggcg gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      481 actctcttcc cg
//
LOCUS       KCVO01001421             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:22109:18054
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001421
VERSION     KCVO01001421.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:22109:18054"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73450.1"
                     /translation="DYYCQVWDSSSDHILF"
     J_segment       390..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           86 a          143 c          136 g           97 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggtct cctatgagtt gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacctt
      181 ggagataaat atgtacactg gtaccagcag aagccaccgc gggcccctgt gctggtcatc
      241 tactatgata gtgaccggcc ctcatggatc cctgagcgat tctctgggtc caaatcaggg
      301 atcaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtagtag tgatcatatc ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001422             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:16197:11917
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001422
VERSION     KCVO01001422.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16197:11917"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73451.1"
                     /translation="DYYCAAWDDSLSSPLF"
     J_segment       397..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           90 a          149 c          120 g          110 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gataatctcc agcatggcct ggttccctct
       61 cgtcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 accctcaacg tctggggctc ccgggcagag tgtcaccatc tcttgctctg gaagcagttt
      181 caacattgga agtaattatg taaactggta ccagcagctc ccaggaacgg cccccaaact
      241 cctcatctat tttagtaatc agcggccctc aggggtccct gaccgattct ctggctctaa
      301 gtctggcacc tcagcctccc tggccatcac tggtctccga tctgaggatg aggctgatta
      361 ttactgtgca gcatgggatg atagtctgag cagtccctta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001423             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:9952:11688
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001423
VERSION     KCVO01001423.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:9952:11688"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..404
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73452.1"
                     /translation="DYYCQSFDSSLSAVLF"
     J_segment       406..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           88 a          154 c          128 g          110 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcccgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacattgg aggttattat gtgcagtggt atcagcaact tccaggaacg
      241 gcccccaaac ttctcatcta tgaaaataat aagcgaccct caggggtttc tgatcgattc
      301 tctggctccc agtctggttc ctcagcctcc ctgaccatca ctggactgca gtctgaggat
      361 gaggctgatt attactgcca gtcctttgac agcagcctga gtgccgtgtt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001424             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:17595:11996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001424
VERSION     KCVO01001424.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:17595:11996"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..441
                     /note="immunoglobulin light chain variable region"
     V_region        112..441
     V_segment       112..404
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73453.1"
                     /translation="DYHCQSYDSNLSAVLF"
     J_segment       406..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>480
                     /gene="IGLC"
BASE COUNT           92 a          154 c          128 g          106 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacattgg aagttattat gtgcagtggt accagcaact tccaggaacg
      241 gcccccaaag ttctcatcta tgaaaataat aagcgaccct caggggtttc tgatcgattc
      301 tctggggccc agtctggtac ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt atcactgcca gtcctatgac agcaacctga gtgccgtgtt attcggaggg
      421 gggacccggc tgaccgtcct aagtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001425             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:9475:11995
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001425
VERSION     KCVO01001425.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:9475:11995"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..401
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73454.1"
                     /translation="DYYCCSYAGRFTFVF"
     J_segment       406..436
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           77 a          158 c          125 g          114 t
ORIGIN      
        1 acatggggct ggggtctcag acggcagcgc tctcgggaca tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct ggcctcaggc tgccctgact
      121 cagcctcgct cagtgtctgg gtctcctgga cagtcggtca ccgtctcctg cactggggcc
      181 agcagtgaca tcggtggttt tgactttgtc tcctggtacc aacagcgtcc aggcacagcc
      241 cccaaactca tgatttatga ggtcagtaag cggccctcag gggtctctga tcgcttctct
      301 ggctccaagt ccggcaacac ggcctccctg accatctctg ggctccaggc tgaggacgac
      361 gctgattatt attgctgctc atatgcaggc aggttcactt ttgtattcgg aagtggcacc
      421 aagttgaccg tcctcggtca gcccaaggct tcccccttgg tcactctgtt cccg
//
LOCUS       KCVO01001426             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:7246:12140
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001426
VERSION     KCVO01001426.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:7246:12140"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73455.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       392..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           90 a          138 c          125 g          107 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagtc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 taatgaggac agcaaacggc cctctgggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggtgc ccaggtggag gatgaagctg actactattg
      361 ttcctcaaca gatagtagtg gtaattatgt tttcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001427             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:17437:5652
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001427
VERSION     KCVO01001427.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:17437:5652"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..404
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73456.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       406..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           88 a          155 c          129 g          108 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagtt ccaacattgg aggttattat gtgcagtggt accagcagct tccaggaacg
      241 gcccccaaac tcctcatgta tgaaaatgat aagcgaccct caggggtttc tgatcgattc
      301 tctggctccc agtctggtac ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgcca gtcctatgac agcagcctga gtgccgtgtt attcggagca
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001428             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:12270:8684
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001428
VERSION     KCVO01001428.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12270:8684"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73457.1"
                     /translation="DYYCYSTRSSGYHGLF"
     J_segment       375..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           90 a          140 c          116 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatctct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtgcaggatg aagctgacta ctactgttac tcaactcgta
      361 gcagtggtta tcatggctta ttcggaggag ggacctggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001429             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:8985:3406
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001429
VERSION     KCVO01001429.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:8985:3406"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73458.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       397..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          141 c          139 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagtc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagactctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaaacc agcgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgtgtatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001430             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:19737:19068
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001430
VERSION     KCVO01001430.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19737:19068"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73459.1"
                     /translation="DYYCSSTDSRDNHRVF"
     J_segment       390..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           94 a          142 c          128 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcgt
      241 ctatgaggac aacaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc acgttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagcaggg ataatcatag ggtattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001431             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:25956:14255
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001431
VERSION     KCVO01001431.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:25956:14255"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..404
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73460.1"
                     /translation="DYYCQSYDTRLRAWVF"
     J_segment       406..442
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           93 a          157 c          124 g          106 t
ORIGIN      
        1 acatgggggt ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtc
      121 ctgacgcagc cgccctcagt gtctggggcg cccggacaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacattgg agattatttt gtacagtggt accaacagct tccaggaacg
      241 gcccccaaac tcctcatcta tgaaaatgat aaacggccct caggagtttc tgatcgattc
      301 tctggctccc agtctggaac ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt actactgcca gtcctatgac accagattga gggcctgggt attcggcgga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001432             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:10733:7805
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001432
VERSION     KCVO01001432.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10733:7805"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73461.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          162 c          119 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc ctttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa caccacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac ttccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001433             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:23020:10479
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001433
VERSION     KCVO01001433.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:23020:10479"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..450
                     /note="immunoglobulin light chain variable region"
     V_region        117..450
     V_segment       117..410
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73462.1"
                     /translation="DYYCSLWDSRLSSRVF"
     J_segment       415..450
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           94 a          156 c          129 g          109 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctctcctt ctcactctgc tggttcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagcatctg gggcccccgg gcagagggtc accatctcct
      181 gcactgggac cagttccaac atcggggcga attattatgt ttcctggtac cagcagttcc
      241 caggaacagc ccccaaactc ctcatctatg aaaacaataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtacct cagcctccct gaccatctct ggactccaat
      361 ctgaggatga ggctgattat tactgctcac tatgggatag caggctgagt agtcgggtat
      421 tcggcggagg gacccgactg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCVO01001434             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:3268:16773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001434
VERSION     KCVO01001434.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:3268:16773"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73463.1"
                     /translation="DYYCSSYASSSNWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           83 a          154 c          125 g          111 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggttcca acagcaccca ggcaaagccc
      241 ccaaactcat gatttgtgac gtcagtgatc ggccctcagg ggtctctgct cgcttctctg
      301 gttccaagtc tggcaatacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacgcaagca gtagtaattg ggtattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001435             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:11467:13246
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001435
VERSION     KCVO01001435.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11467:13246"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73464.1"
                     /translation="DYYCQSADISGNHPVF"
     J_segment       398..428
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          101 a          137 c          121 g          107 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 gctggcaaaa acatatgctc agtggttcca gcagaagcca ggccaggccc ctgtcttggt
      241 tatatataaa gacagtgaga ggccctccgg gatccctgag cgattctcta gctccagttc
      301 agggccaaca gttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca gcagacatca gtggtaatca tcctgttttc ggaagtggca ccaagttgac
      421 cgtcctcggt cagcccaagg cttccccctt ggtcactctg ttcccg
//
LOCUS       KCVO01001436             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:11276:9551
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001436
VERSION     KCVO01001436.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11276:9551"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73465.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       396..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          146 c          132 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgag ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaacc
      181 ttggaaataa atatctacac tggtaccacc agaagccagc gcaggcccct gtgctggtca
      241 tctactatga tagtgaccgg ccctcatgga tccctgagcg attctctggg tccaagtcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtaat aatgatcata tctttttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001437             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:15986:15708
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001437
VERSION     KCVO01001437.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:15986:15708"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..382
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73466.1"
                     /translation="DYYCQVWDSITAQWVF"
     J_segment       391..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           83 a          147 c          140 g           95 t
ORIGIN      
        1 acatgggggc tggcctcggg aagcagcctt ggcggtgcct cagccatggc cgggaccctt
       61 ctcctcctcg gcctccttgc tcactgcaca ggctttgcgg tctcctatga gctgactcag
      121 ccacgctcag tgtccgtgtc cccaggacag acggcccgga tcacctgtgg gggagacaac
      181 attggaagta aaagtgtgca gtggttccag cagaggccac cgcaggcccc tgtgctggtc
      241 atttatactg ataaccagcg gccctcaggg atccctgagc gattctctgg ctccaactca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg ggaatgaggc tgactattat
      361 tgtcaggtgt gggacagtat tactgctcag tgggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001438             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:14320:14819
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001438
VERSION     KCVO01001438.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:14320:14819"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73467.1"
                     /translation="DYYCYSTDSSGNGLF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           95 a          142 c          123 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 cccagaaaaa tttgcttatt ggtaccagca gaaaccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gacagcagtg gtaatggctt attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001439             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:14586:7349
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001439
VERSION     KCVO01001439.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14586:7349"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73468.1"
                     /translation="DYYCAAWDDSLNSPFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          154 c          114 g          106 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaac
      181 attggaagta attatgtaaa ctggtaccag caactcccag gaacggcccc caaactcctc
      241 atctatttta ctaatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcggcat gggatgacag cctgaacagt cccttcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgtcccctcg gtcactctct tcccg
//
LOCUS       KCVO01001440             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:17544:6090
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001440
VERSION     KCVO01001440.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17544:6090"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73469.1"
                     /translation="DYYCFSSDSSADYWVF"
     J_segment       390..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>464
                     /gene="IGLC"
BASE COUNT           89 a          142 c          128 g          105 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccagaaaa atatgcttat tggttccagc agaagccagg ccagtcccct gtgttgatca
      241 tctatgagga caccaaacgg ccctctggga tccctgagag attctctggt tccagctcag
      301 ggacagtggc caccttgact atcagtgggg cccaggtgga ggatgaagct gactactact
      361 gtttctcatc agatagcagt gctgattatt gggtgttcgg cggagggacc cggctgaccg
      421 tcccaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001441             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:18354:13343
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001441
VERSION     KCVO01001441.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18354:13343"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73470.1"
                     /translation="DYYCQVWDSRSDHNLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          143 c          138 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctcgctc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gtgggaggca
      181 atgttggaag tgaatatgtc cactggtatc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatctatta taatactgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt aggagtgatc ataatttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001442             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:20716:10199
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001442
VERSION     KCVO01001442.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:20716:10199"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..385
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73471.1"
                     /translation="DYYCQVWDTSDHPLF"
     J_segment       387..421
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           85 a          149 c          132 g           93 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctta ctgcacagcg tctgcggtct cccatgacct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacactctt
      181 gggagtaaat atgtccactg gtaccagcag aagccagcgc aggcccctgt gttggtcatc
      241 cattataata gtgaccggcc ctcagggatc cctgaccgat tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtatggg acactagtga tcatccgtta ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001443             316 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:25132:8697
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001443
VERSION     KCVO01001443.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 316)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:25132:8697"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..278
                     /note="immunoglobulin light chain variable region"
     V_region        8..278
     V_segment       8..238
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <203..>250
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73472.1"
                     /translation="DYYCYSTVSSGNERIF"
     J_segment       245..278
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        279..>316
                     /gene="IGLC"
BASE COUNT           72 a           88 c           86 g           70 t
ORIGIN      
        1 acatgggagg atcacctgct ctggagatgc attgccaaaa aaatatgctt attggttcca
       61 gcagaagcca ggccagtccc ctgtgctgat catctatgag gacagcaaac ggccctctgg
      121 gatccctgag agactctctg gctccagctc agggacagtg gccaccttga ctatcagtgg
      181 ggcccaggtg gaggatgaag ctgactacta ctgttactca acagttagta gtggtaatga
      241 aaggatcttc ggtgctggga cccggctcac cgtcctaggt cagcccaagg cttcccccac
      301 ggtcactctg ttcccg
//
LOCUS       KCVO01001444             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:12627:20843
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001444
VERSION     KCVO01001444.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12627:20843"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..424
                     /note="immunoglobulin light chain variable region"
     V_region        101..424
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73473.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       393..424
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>463
                     /gene="IGLC"
BASE COUNT           95 a          142 c          124 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgcgcag gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaagac gacaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaaagtg actactactg
      361 ttactcaata gatagtagtg gtagtcatag cgtcttcggt gctgggaccc ggctcaccgt
      421 cctacgtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001445             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:9235:12150
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001445
VERSION     KCVO01001445.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9235:12150"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..422
                     /note="immunoglobulin light chain variable region"
     V_region        104..422
     V_segment       104..385
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73474.1"
                     /translation="DYYCQSTDSSGFIF"
     J_segment       388..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT          104 a          138 c          118 g          100 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 accaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actgacaaaa caatatgctc agtggttcca gcagaagcca ggccaggccc ctgtgctggt
      241 gatatataaa gacactgaga ggccctcagg gatccctgag cgaatctcta gctccagttc
      301 agggacatca attaccctga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca acagacagca gtggtttcat cttcggtgct gggacccggc tcaccgtcct
      421 aggtcagctc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01001446             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:5882:13869
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001446
VERSION     KCVO01001446.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5882:13869"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..400
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73475.1"
                     /translation="DYYCGSYGSGNIFLF"
     J_segment       405..435
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           82 a          153 c          128 g          110 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcgct ctcgggacgt ctccaccatg gcttgggctc
       61 tggtcctcct caccctcctc actcagggca caggatcctg ggctcagtct gccctgactc
      121 agcctccctc agtgtccaag tctcttggac agtccgtcac catctcctgc actggaacca
      181 aaaatgacat tggtgggttt aacggtgtct cctggtacca gcgacactca ggcacagccc
      241 ccggactcct actttatgag gtcaataggc ggccctcagg ggtctctaat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatttctgg gctccaggct gaggatgagg
      361 ctgattatta ctgcggctcg tacgggagtg gaaacatttt tttgttcgga ggcgggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001447             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:23724:15552
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001447
VERSION     KCVO01001447.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23724:15552"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..430
                     /note="immunoglobulin light chain variable region"
     V_region        104..430
     V_segment       104..399
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73476.1"
                     /translation="DYFCSSYTGSITLF"
     J_segment       400..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>469
                     /gene="IGLC"
BASE COUNT           86 a          158 c          117 g          108 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcaggacgtc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtgcttata actatgtctc ctggtaccaa cggcacccag gcaaagcccc
      241 caaactcatg atttatgatg tcaataagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaaatct ggcaacacgg cctccctgac catctctggg ctccagtctg aggatgaggc
      361 tgattatttc tgcagctcat atacaggcag catcacttta ttcggaggag ggacccggct
      421 gaccgtccta cgtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001448             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:22656:10105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001448
VERSION     KCVO01001448.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22656:10105"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73477.1"
                     /translation="DYYCQVWDSSSDHCLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          143 c          139 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaag tgaatatgtg cactgttacc aacagaggcc accgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001449             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:18609:10874
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001449
VERSION     KCVO01001449.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18609:10874"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..439
                     /note="immunoglobulin light chain variable region"
     V_region        94..439
     V_segment       94..403
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73478.1"
                     /translation="DYYCVIWNNNAWVF"
     J_segment       404..439
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        440..>477
                     /gene="IGLC"
BASE COUNT           94 a          151 c          118 g          114 t
ORIGIN      
        1 acatggggga ctgcagggaa agaggctgtg tccaccatgg cctggactcc tctcctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcgcagcctg tgctgactca gccaacctcc
      121 ctctcagcat ctcctggagc atcagccaga ctcacctgca ccttgagcag tgacatcagt
      181 gttggtagtt acaggatatt ctggtaccag cagaagccag ggagtcctcc ccggtatctt
      241 ctgaattacc acacagactc agataaacac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcggc caatgcaggg atttttctca tctctgggct ccagtctgag
      361 gatgaggctg actattactg tgtgatttgg aacaacaatg cttgggtttt cggcggaggg
      421 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001450             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:19627:6164
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001450
VERSION     KCVO01001450.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:19627:6164"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73479.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           91 a          142 c          125 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tactgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc cctggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagtagtg gtaattatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001451             404 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:9055:3443
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001451
VERSION     KCVO01001451.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 404)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:9055:3443"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    42..366
                     /note="immunoglobulin light chain variable region"
     V_region        42..366
     V_segment       42..329
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <291..>338
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73480.1"
                     /translation="DYYCQVWDSRSDHNLL"
     J_segment       333..366
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        367..>404
                     /gene="IGLC"
BASE COUNT           84 a          118 c          116 g           86 t
ORIGIN      
        1 acatgggcgg cctccttgct tactgcacag gctctgcggt ctcctatgag ctcactcagc
       61 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggaggcaatg
      121 ttggaagtga atatgtccac tggtatcaac agaagccacc gcaggcccct gtcgtggtca
      181 tctattataa tactgaccgg ccctcaggga tccctgagcg attctctgga ttcaaatcag
      241 ggaacaccgc caccctgacc atcagcgggg tcgagaccgg ggatgaggct gactattact
      301 gtcaggtgtg ggacagtagg agtgatcata atttattggg aggagggacc cggctgaccg
      361 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001452             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:13869:4565
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001452
VERSION     KCVO01001452.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13869:4565"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73481.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       392..424
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           99 a          137 c          123 g          103 t
ORIGIN      
        1 acatggggtg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactccccc tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agatgcattg
      181 ccaaaaaaat atgtatattg gttccagcag aagccaggcc agtcccctgt gttgatcatc
      241 tatgaggaca acaaacggcc ctctgggatt cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cagtggggcc caggtggagg atgaaggtga ctactactgt
      361 tactcaagag atagtagtga aaatcaaagc gtcttcggtg ctgggacccg gctcagcgtc
      421 ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01001453             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:11139:9858
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001453
VERSION     KCVO01001453.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:11139:9858"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73482.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          161 c          126 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctgggggc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001454             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:16419:18398
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001454
VERSION     KCVO01001454.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:16419:18398"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73483.1"
                     /translation="DYYCHSLDTSGNDVF"
     J_segment       392..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           89 a          143 c          125 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttact ggttccagca gaagccaggc cagtcccctg tggtgatcat
      241 ctatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 tcattcatta gataccagtg gtaatgatgt tttcggcggg gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001455             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:15911:16416
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001455
VERSION     KCVO01001455.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15911:16416"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..418
                     /note="immunoglobulin light chain variable region"
     V_region        101..418
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73484.1"
                     /translation="DYYCHSLDTSGYDVF"
     J_segment       392..418
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        419..>460
                     /gene="IGLC"
BASE COUNT           90 a          142 c          124 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacaga ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcgtt
      181 gccaaaaaaa tttgcttact ggttccagca gaagccaggc cagtcccctg tggtgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgacaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 tcactcatta gataccagtg gttatgatgt tttcggcgga gggacccggc tgaccgtctt
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001456             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:19763:17181
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001456
VERSION     KCVO01001456.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:19763:17181"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73485.1"
                     /translation="DYYCQVWDSSSDHPIF"
     J_segment       392..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           81 a          147 c          134 g          102 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag tctctgcggt ctcctatgag ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacgga cggccacgat cacctgtggg ggagacatcg
      181 ttggaagtga atatgttcac tggtatcagc agaagtcaac gcaggcccct gtggtggtca
      241 tctattatta ttctgaccgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggagcaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactactact
      361 gtcaggtgtg ggacagtagt agtgatcatc ccatcttcgg tgctgggacc cggctcaccg
      421 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCVO01001457             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:4276:15138
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001457
VERSION     KCVO01001457.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:4276:15138"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73486.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          155 c          121 g          114 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtacttata actatgtctc ctggtaccaa cagcatccag gcacagcccc
      241 caaactcatg atttttgagg tcagtgagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgttgctcat atgcagacac ctatactttt gtgtttggag gtggcaccag
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01001458             508 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:23341:6433
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001458
VERSION     KCVO01001458.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 508)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:23341:6433"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    146..470
                     /note="immunoglobulin light chain variable region"
     V_region        146..470
     V_segment       146..431
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <395..>442
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73487.1"
                     /translation="DYYCQVWDSSSKCVLF"
     J_segment       437..470
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        471..>508
                     /gene="IGLC"
BASE COUNT          107 a          154 c          147 g          100 t
ORIGIN      
        1 acatgggggc cagtaagagg ataagagaag cctgggaggc acctgccctg tctgggcctc
       61 aggaggcagc attgacggtg cctcagccat ggcctggacc cttctcctcc tcggcctcct
      121 cgctcactgc acaggctctg cggcctccta tgatctgact cagccaccct cggtgtcagc
      181 ggcctcagga cagacggcca ggatcacctg tgggggagac aacattggaa gtaaaaattt
      241 acactggtac cagcagaagc cagcgcaggc ccctgtgttg gtcatctgtg ctgataataa
      301 acggccctca gggatccctg agcgaatctc tggctccaac tcaggaaaca ccgccaccct
      361 gaccatcagc ggggtcgagg ccggggatga ggctgactat tactgtcagg tttgggacag
      421 tagtagtaaa tgcgttttat tcggaggagg gacccgactg accgtcctag gtcagcccaa
      481 ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001459             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:16939:12075
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001459
VERSION     KCVO01001459.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:16939:12075"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73488.1"
                     /translation="EYYCSSYADIYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          161 c          117 g          108 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg cctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca cgggcaccag
      181 cagtgacatc ggtggttaca actttgtctc ctggtaccaa caccatccag acacagcccc
      241 caaactcgtg atttatgagg tcactcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgaatattac tgcagttcat atgcagacat ctacacattt gtgttcggaa gtggcaccaa
      421 attgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01001460             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:11866:18601
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001460
VERSION     KCVO01001460.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11866:18601"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..390
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73489.1"
                     /translation="EYHCFSTDSTGNHRGLF"
     J_segment       394..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           92 a          147 c          126 g          103 t
ORIGIN      
        1 acatggggct gtgggctcag gaggcagagc tctgggtgtc tcaccatggc ctggattcct
       61 ctcctactcc ccctcctcac tttctgcaca ggctctgcag cctcctatga gctgacacag
      121 gcaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgctc tggagatgca
      181 ttgccacaaa aatttgcttc ttggttccag cagaagccag gccagtcccc tgtgctgatc
      241 atctatgacg acagcaaacg gccctctggg atccctgaga gattctctgg ctccagctca
      301 gggacagtgg ccaccttgac tatcactggg gcccaggtgg aggatgaagc tgagtaccac
      361 tgtttctcaa cagatagcac tggtaatcat aggggcttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001461             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:14179:20087
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001461
VERSION     KCVO01001461.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14179:20087"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..423
                     /note="immunoglobulin light chain variable region"
     V_region        101..423
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73490.1"
                     /translation="DYYCYSSDISGNHRVF"
     J_segment       390..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>463
                     /gene="IGLC"
BASE COUNT           95 a          140 c          122 g          106 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgacc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tactgatcat
      241 ctatgaagac agtaaacggc cctctgggat ccctgagaga ttctctggct ccagttcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagttg actactactg
      361 ttactcatca gatatcagtg gtaatcatag ggtattcggc ggagggaccc ggctgaccgt
      421 ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001462             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:4719:16885
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001462
VERSION     KCVO01001462.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:4719:16885"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73491.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       393..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           98 a          138 c          123 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgtatatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac aacaaacggc cctctgggat tcctgagaga ttctctggct ccagctccgg
      301 gacagtggcc accttgacta ttagtggggc ccaggtggag gatgaaggtg actactactg
      361 ttactcaaga gatagtagtg aaaatcaaag cgtcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001463             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:9470:16802
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001463
VERSION     KCVO01001463.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:9470:16802"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73492.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       393..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           95 a          145 c          125 g          102 t
ORIGIN      
        1 acatgggggg ctatgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccctcctc actttctgca caggctctgc agcctcctct gagctgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg
      181 cattgtcaaa atactatgct tattggttcc agcagaagcc aggccagtcc cctgtggcga
      241 tcatctatga ggacaacaaa cggccctctg ggatccctga gagaatctct ggctccagct
      301 cagggacagt ggccaccttg actatcagtg gggcccaggt cgaggatgaa gctgactact
      361 actgttactc aacagatagc agtggtacta atggcttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001464             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:19875:13200
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001464
VERSION     KCVO01001464.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19875:13200"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73493.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       379..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           96 a          134 c          117 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 tatattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaggacaaca
      241 aacggccctc tgggattcct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactgtcag tggggcccag gtggaggatg aaggtgacta ctactgttac tcaagagata
      361 gtagtgaaaa tcaaagtgtc ttcggtgctg ggacccggct cagcgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001465             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:16418:12764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001465
VERSION     KCVO01001465.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16418:12764"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73494.1"
                     /translation="DYYCYSTDSGTNHGLF"
     J_segment       375..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           94 a          142 c          115 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtact gatcatctat gaggacagca
      241 aacggccccc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagata
      361 gcggtactaa tcatggctta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001466             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:8945:7765
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001466
VERSION     KCVO01001466.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:8945:7765"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73495.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          161 c          124 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagagttag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001467             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:13551:6175
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001467
VERSION     KCVO01001467.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:13551:6175"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..435
                     /note="immunoglobulin light chain variable region"
     V_region        102..435
     V_segment       102..398
                     /gene="IGLV6-91"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73496.1"
                     /translation="DYYCQSADGSYNPVF"
     J_segment       405..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           84 a          157 c          130 g          102 t
ORIGIN      
        1 acatgggggg tggctcagga agcagagcct ggagcgtctc caccatggcc tgggctccac
       61 tcctcctcac cctcctcgct cactgcacag ggtcttgggc tgaggttgtg ttcactcagc
      121 cccattctgt gtcggggtct ccggggcaga cggtcaccat ctcctgtacc cgcagcagtg
      181 gcagcattga cagtaaatat gtgctgtggt accagcagcg cccgggcagt gccccaacca
      241 gaatgattta caaagataag caaagaccct ctggggtccc tgatcggttc tctggctcca
      301 tcgacagctc ctccaactct gcctccctca ccatctctgg gctgaactct gaggacgagg
      361 ctgactacta ctgtcagtct gctgatggca gctacaatcc ggtgttcggc ggggggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001468             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:6980:16144
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001468
VERSION     KCVO01001468.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6980:16144"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73497.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          152 c          124 g          113 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttttg agcgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcttg atttatgagg tcagttatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct gccaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattat tgcagctcat acacaagtag tagtacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001469             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:20556:4991
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001469
VERSION     KCVO01001469.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:20556:4991"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73498.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       392..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           90 a          143 c          125 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tttgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagttcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagcagtg gtaatcatgt tttcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001470             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:9917:18852
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001470
VERSION     KCVO01001470.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:9917:18852"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73499.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           96 a          143 c          123 g           98 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacggcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggtaccagca gaaaccaggc cagtccccta tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgaaaga ttctctggct ccagctcagg
      301 gacagtggcc accttgatta tcactggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacaacagtg gtcagggctc attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001471             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:9855:5040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001471
VERSION     KCVO01001471.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:9855:5040"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73500.1"
                     /translation="DYYCQSGDSSSNHYIF"
     J_segment       392..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          104 a          138 c          121 g          103 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatgctc ggtggttcca gcagaagcca ggccaggccc ctgtgctggt
      241 gatatataaa gacactgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaata cttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca ggagacagca gttctaatca ttacatcttc ggtgctggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCVO01001472             428 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:18783:19627
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001472
VERSION     KCVO01001472.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 428)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18783:19627"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    174..390
                     /note="immunoglobulin light chain variable region"
     V_region        174..390
     V_segment       174..351
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <315..>362
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73501.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       360..390
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        391..>428
                     /gene="IGLC"
BASE COUNT           79 a          142 c          111 g           96 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccaatctgtg
      121 atgacgcagc cgccctcact gtctggggcg cccgggcagg gggtcaccat ctccagcttc
      181 caggaacggc ccccaaactc ctcatctatg aaaataataa gcgaccctca gggatttctg
      241 atcgattctc tggctcccag tctggtacct cagcctccct gaccatcact ggactgcagt
      301 ctgaggatga ggctgattat tattgccagt cctatgacag cagcctgagt gtcgtattgt
      361 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      421 tcttcccg
//
LOCUS       KCVO01001473             343 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:5526:12640
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001473
VERSION     KCVO01001473.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 343)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:5526:12640"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..305
                     /note="immunoglobulin light chain variable region"
     V_region        8..305
     V_segment       8..266
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <230..>277
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73502.1"
                     /translation="DYYCAAWDNSLNNVLF"
     J_segment       268..305
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        306..>343
                     /gene="IGLC"
BASE COUNT           72 a          107 c           84 g           80 t
ORIGIN      
        1 acatgggggg gctcccgggc agactgtcac catctcttgc tctggaagca gctccaacat
       61 tggaagtaat tatgtatact ggtaccagca attcccagga acggccccca aactcctcat
      121 ctattatact aatcagcgac cctcaggggt ccctgaccga ttctctggct ctaagtctgg
      181 cacctcagcc tccctggcca tcactggtct ccgatctgag gatgaggctg attattactg
      241 tgcagcctgg gataacagcc tgaacaatgt gttattcgga ggagggaccc ggctgaccgt
      301 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001474             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:11289:8042
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001474
VERSION     KCVO01001474.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11289:8042"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73503.1"
                     /translation="DYHCFSTDTSGNHRGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           94 a          145 c          123 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatatatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgacgac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcattggggc ccaggtggag gatgaagctg actaccactg
      361 tttctcaaca gataccagtg gtaatcatag gggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001475             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:24850:4419
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001475
VERSION     KCVO01001475.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:24850:4419"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..393
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73504.1"
                     /translation="DYYCCSYAGTYLF"
     J_segment       394..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           84 a          156 c          118 g          107 t
ORIGIN      
        1 acatgggggg gtctcagacg gcagcgctct cgggacatct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 cctcgctcag tgtctgggtc tcctggacag tcggtcacca tctcctgctc tggaaccagc
      181 agtgacatcg gtgcttataa ctatgtctcc tggtaccaac aaattccagg cacagccccc
      241 aaactcataa tttatgaggt ccgtaagcgg ccctcagggg tctctgatcg cttttctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctggac tccaggctga ggacgagggt
      361 gattattact gctgttcata tgcaggcacc tacttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001476             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:22510:18920
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001476
VERSION     KCVO01001476.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22510:18920"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73505.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          143 c          137 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgac ctcactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggaggcaatg
      181 ttggaagtga atatgtccac tggtatcaac agaagccacc gcaggcccct gtggtggtca
      241 tctattataa tactgaccgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagg agtgatcata gtttattggg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001477             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:8909:16465
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001477
VERSION     KCVO01001477.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:8909:16465"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73506.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       393..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          145 c          126 g          103 t
ORIGIN      
        1 acatggggct gtgggctcag gaggcagagc tctgggtgtc tcaccatggc ctggattcct
       61 ctcctactcc ccctcctcac tttctgcaca ggctctgcag cctcctatga gctgacacag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgctc tggagatgca
      181 ttgccaaaaa agtatgctta ttggttccag cagaagccag gccagtcccc tgtgctgatc
      241 atctatgagg acagcagacg gccctctggg atccctgaga gattctctgc ctccagctca
      301 gggacagtgg ccaccttgac tatcagtggg gcccaggggg aggatgaagc tgactactac
      361 tgttattcaa tggatagcag tggtactcag agcatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCVO01001478             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:11639:10487
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001478
VERSION     KCVO01001478.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:11639:10487"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73507.1"
                     /translation="DYYCYSADSSGNGLF"
     J_segment       384..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           95 a          139 c          125 g           99 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcgttgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 cagaaaaata tgcgtattgg tatcagcaga aaccaggcca gtcccctgtg catatcatct
      241 atgaggacag caagcggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc agtggggccc aggtggagga tgaagctgac tactactgtt
      361 actcagcaga cagtagtggt aatggcttat tcggaggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001479             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:19894:8807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001479
VERSION     KCVO01001479.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19894:8807"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..381
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73508.1"
                     /translation="DYYCQVWDYISAHPLF"
     J_segment       394..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           90 a          139 c          133 g          100 t
ORIGIN      
        1 acatggggga ctttgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctttacagac tctgcggcct cctatgaact gactcagtca
      121 cgctcggtgt cggtgtccca gggacagacg gccaggatca cctgtggggg aaacaacatt
      181 cgaagtgcag ttgtgcagtg gtaccagcag aagccaacgc aggcccctgt gttggtcatc
      241 tatgatgata ccaaacggcc ctcagggatc cctgatcgag tctctggatc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtttggg attatattag tgctcatcca ttgttcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001480             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:22032:6508
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001480
VERSION     KCVO01001480.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:22032:6508"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..412
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73509.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       414..449
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           93 a          157 c          129 g          108 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggacccc gggcagaggg tcaccatctc
      181 gtgcactggg aacagctcca acattggagg ttattttgta tactggtacc agcagttccc
      241 aggaacagcc cccaaactcc tcatctatga caataataag cgaccctcag ggatttctga
      301 ccgattctct ggctccaagt ctggtacctc agcctccctg accatcactg ggctccagcc
      361 tggggatgag gctgattatt actgcggagc atgggatagc agcctgagtg ctcgcttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCVO01001481             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:16592:20632
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001481
VERSION     KCVO01001481.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16592:20632"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    78..408
                     /note="immunoglobulin light chain variable region"
     V_region        78..408
     V_segment       78..372
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73510.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       373..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           77 a          155 c          110 g          104 t
ORIGIN      
        1 acatggggga cgtctccacc atggcctggg ctctgctcct cctcaccctc ctcactcagg
       61 gcacaggatc ctgggctcag gctgccctga ctcagtctcc ctctgtgtct gggtctcctg
      121 gacagtcggt caccctttcc tgcactggaa ccagcagtga cattggtggt tataaccgtg
      181 tctcctggta ccaacaccac ccaggcaaag cccccaaact catgatttat gacgtcagtg
      241 atcggccctc aggggtctct gatcgcttct ctggttccaa gtctggcaac acggcctccc
      301 tgatcatctc tgggctccag gctgaggacg aggctgatta ttactgcagc tcatacgcaa
      361 gcacttccac ttggctattc ggcggaggga cccgcctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001482             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:4049:10728
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001482
VERSION     KCVO01001482.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:4049:10728"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73511.1"
                     /translation="DYYCYSTDSSGNHIF"
     J_segment       387..421
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           94 a          145 c          119 g          101 t
ORIGIN      
        1 acatgggggg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactccccc tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agatgcattg
      181 ccaaaaaagt atgcttattg gttccagcag aagccaggcc agtcccctgt gctgatcatc
      241 tatgacgaca gtaaacggcc ctctgggatc cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cagtggggcc caggtggagg atgaagctga ctactactgt
      361 tactcaacag atagcagtgg taatcacatc ttcgctactg ggacccggct caccgtccta
      421 ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001483             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:24486:4079
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001483
VERSION     KCVO01001483.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:24486:4079"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..392
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73512.1"
                     /translation="DYYCFVYYSGTQFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           99 a          154 c          115 g           97 t
ORIGIN      
        1 acatgggggg agccagagat cccttccaat accagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtggctc cagcactgga
      181 gcagtcacca gtggtaactt tccaaactgg ttccagcaga aacctggaca agtccccagg
      241 ggactgattt acaatacaaa caacaaacac ccctggaccc ctgcccggtt ctcaggctcc
      301 ctcgctgggg gcaaagctgc cctgacactg tcaggagcac agcccgagga cgaggctgat
      361 tattactgct tcgtgtacta tagtggtact caattcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001484             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:12514:17558
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001484
VERSION     KCVO01001484.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12514:17558"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..393
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73513.1"
                     /translation="DYYCFVYYSGTQFF"
     J_segment       398..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           99 a          153 c          115 g           99 t
ORIGIN      
        1 acatggggtg gagccagaga tcccttccaa taccagcacc atggcctgga ctctgctcct
       61 cctccagttc ctcctcactt gctgcccagg gtccaattct caggctgtag tgactcagga
      121 gccctcaatg actgtgtccc caggagggac agtcactctc acctgtggct ccagcactgg
      181 agcagtcacc agtggtaact ttccaaactg gttccagcag aaacctggac aagtccccag
      241 gggactgatt tacaatacaa acaacaaaca ctcctggacc cctgcccggt tctcaggctc
      301 cctcgctggg ggcaaagctg ccctgacact gtcaggagca cagcccgagg acgaggctga
      361 ttattactgc ttcgtgtact atagtggtac tcaattcttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001485             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:13735:18074
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001485
VERSION     KCVO01001485.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13735:18074"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73514.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           94 a          144 c          124 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctctgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gtcaaaatac tatgcttatt ggttccagca gaagccaggc cagtcccctg tggcgatcat
      241 ctatgaggac aacaaacggc cctctgggat ccctgagaga atctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtcgag gatgaagctg actactactg
      361 ttactcaaca gatagcagtg gtactaatgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001486             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:13868:17854
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001486
VERSION     KCVO01001486.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13868:17854"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73515.1"
                     /translation="DYYCYSADSSGNGLF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           93 a          137 c          117 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cgtattggta tcagcagaaa ccaggccagt cccctgtgca tatcatctat gaggacagca
      241 agcggccctc tgggatccct gagagattct cttgctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 gtagtggtaa tggcttattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001487             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:20978:17566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001487
VERSION     KCVO01001487.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20978:17566"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73516.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       391..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           93 a          156 c          114 g          102 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcctc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cacctccaac
      181 atcggaacta atagtgtatc ctggtaccag cagctcccag aaacggctcc caaactcctc
      241 atctattata atgatcgacg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcagcat gggataacag cctgagcggt tacatcttcg gtgctgggac ccggctcacc
      421 gtcctaggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCVO01001488             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:6741:6332
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001488
VERSION     KCVO01001488.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:6741:6332"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73517.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       375..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           91 a          143 c          116 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct ctgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaatactatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtggc gatcatctat gaggacaaca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtcgaggatg aagctgacta ctactgttac tcaacagata
      361 gcagtggtac taatggctta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001489             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:14328:7607
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001489
VERSION     KCVO01001489.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14328:7607"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73518.1"
                     /translation="HYYCCSYADTYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           78 a          161 c          121 g          112 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatccttg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggcaccag
      181 cagtgacatc ggtggttata actttgtctc ctggtaccag caccatccag gcacagcccc
      241 caaactcgtg atatatgagg tcactcagcg gccctcgggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacgcgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tcattattac tgctgctcat atgcagacac ttacactttt gtgttcggag gtggcaccaa
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01001490             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:17344:15547
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001490
VERSION     KCVO01001490.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17344:15547"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73519.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       391..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           87 a          142 c          138 g           95 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggtct cctatgacct gactcagcca
      121 ccctcggtgt cagtgccccc aggacagacg gccaggatca cctgtgtggg agacaatgtt
      181 ggaagtgaat atgtgcactg gtaccaacag aagccaccgc aggcccctgt ggtggtcatc
      241 cattataata gtgaccggcc ctcagggatc cctgaacgat tctctggctc caaatcaggg
      301 agcgccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtagtag tgatcatagt ttattgggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001491             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:12857:4245
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001491
VERSION     KCVO01001491.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:12857:4245"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..412
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73520.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       416..449
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           92 a          155 c          130 g          110 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggacccc gggcagaggg tcaccatctc
      181 gtgcactggg agcagctcca acattggagg ttattttgta tactggtacc atcagttccc
      241 aggaacagcc cccaaactcc tcatctatga caataataag cgaccctcag ggatttctga
      301 ccgattctct ggctccaagt ctggtacctc agcctccctg accatcactg ggctccagcc
      361 tggggatgag ggtgattatt actgcggagc atgggatagc agcctgagtg ctcgtttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCVO01001492             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:22330:7169
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001492
VERSION     KCVO01001492.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:22330:7169"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..390
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73521.1"
                     /translation="DYSCLSYDSSLSAHYIF"
     J_segment       393..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           91 a          164 c          110 g          103 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctcgtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagc ctgtgctgac acagccaccc
      121 tcagtgtctg gggccccagg gcagagggtc accatctcgt gcactgggag cagctccaac
      181 attggaggtg attctgtatc ctggtaccaa catctcccag gcacgacccc caaactcctc
      241 atctatcaaa ataataagcg accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggtacctcag cctccctgac catcactggg ctccagactg aggatgaggc tgattactcc
      361 tgcctgtcct atgacagcag cctgagtgct cattacatct tcggtcctgg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCVO01001493             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:16239:17554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001493
VERSION     KCVO01001493.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16239:17554"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..395
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73522.1"
                     /translation="DYYCFVYYSGTQFF"
     J_segment       400..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           99 a          154 c          115 g          100 t
ORIGIN      
        1 acatggggtc tggagccaga gatcccttcc aataccagca ccatggcctg gactctgctc
       61 ctcctccagt tcctcctcac ttgctgccca gggtccaatt ctcaggctgt agtgactcag
      121 gagccctcaa tgactgtgtc cccaggaggg acagtcactc tcacctgtgg ctccagcact
      181 ggagcagtca ccagtggtaa ctttccaaac tggttccagc agaaacctgg acaagtcccc
      241 aggggactga tttacaatac aaacaacaaa cactcctgga cccctgcccg gttctcaggc
      301 tccctcgctg ggggcaaagc tgccctgaca ctgtcaggag cacagcccga ggacgaggct
      361 gattattact gcttcgtgta ctatagtggt actcaattct tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001494             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:16705:3264
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001494
VERSION     KCVO01001494.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:16705:3264"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..428
                     /note="immunoglobulin light chain variable region"
     V_region        98..428
     V_segment       98..391
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73523.1"
                     /translation="DYYCAAWDDSLNSPFF"
     J_segment       398..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           91 a          155 c          115 g          105 t
ORIGIN      
        1 acatggggga cagaaggcag gactcaggat aatctccagc atggcctggt tccctctcgt
       61 cctcaccctc ctcactcact gtgcagggtc ctgggcccag tctgtgctga ctcagccacc
      121 ctcaacgtct ggggctcccg ggcagagtgt caccatctct tgctctggaa gcagctccaa
      181 cattggaagt aattatgtaa actggtacca gcaactccca ggaacggccc ccaaactcct
      241 catctatttt actaatcagc gaccctcagg ggtccctgac cgattctctg gctctaagtc
      301 tggcacctca gcctccctgg ccatcactgg tctccgatct gaggatgagg ctgattatta
      361 ctgtgcggca tgggatgaca gcctgaacag tcccttcttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001495             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:13310:22972
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001495
VERSION     KCVO01001495.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:13310:22972"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73524.1"
                     /translation="DYYCQSGDSSANHYIF"
     J_segment       389..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          103 a          136 c          121 g          103 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatgttcggt ggttccagca gaagccaggc caggcccctg tgctggtgat
      241 atataaagac actgagaggc cctcagggat ccctgagcga ttctctggct ccagttcagg
      301 gacaatactt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagga gacagcagtg ctaatcatta catcttcggt gctgggaccc gtctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001496             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:23148:14331
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001496
VERSION     KCVO01001496.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:23148:14331"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..447
                     /note="immunoglobulin light chain variable region"
     V_region        114..447
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73525.1"
                     /translation="DYFCSVWDSSLTIYIF"
     J_segment       410..447
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           88 a          158 c          126 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtccggg gcccagcctg
      121 tgctgacgca gccgccctca gcatctgggg cccccgggca gagggtcacc atctcctgca
      181 ctgggagcag ctccaacatc ggggcgggtt attctgtatc ctggtatcag cagttcccag
      241 gaacagcccc caaactcctc atctatgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac tatcactgga ctccaatctg
      361 aggatgaggc tgattatttc tgctctgtct gggatagcag cctgactatt tacatcttcg
      421 gtgctgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt
      481 tcccg
//
LOCUS       KCVO01001497             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:21384:22280
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001497
VERSION     KCVO01001497.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21384:22280"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73526.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           84 a          161 c          120 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctccggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001498             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:21399:11805
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001498
VERSION     KCVO01001498.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21399:11805"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73527.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          142 c          138 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgag ctcactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggaggcaatg
      181 ttggaagtga atatgtccac tggtatcaac agaagccacc gcaggcccct gtggtggtca
      241 tctattataa tactgaccgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagg agtgatcata gtttattggg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001499             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:8530:13253
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001499
VERSION     KCVO01001499.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:8530:13253"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73528.1"
                     /translation="DYYCQVWDSSSDVFF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           84 a          142 c          141 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcattggaag tacaggtgtg cagtggtacc agcagaagcc accgctggcc cttgtactgg
      241 tcatctatgc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctgcaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttcttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001500             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:11349:10021
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001500
VERSION     KCVO01001500.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:11349:10021"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..388
                     /note="immunoglobulin light chain variable region"
     V_region        58..388
     V_segment       58..352
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <316..>360
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73529.1"
                     /translation="DYYCCSYRSGNTYVF"
     J_segment       353..388
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        389..>426
                     /gene="IGLC"
BASE COUNT           78 a          138 c          109 g          101 t
ORIGIN      
        1 acatgggggg ctctgctcct cctcagcctc ctcactcagg gcacaggatc ctgggctcag
       61 gctgccctga ctcagcctcc ctcagtgtcc aagtctcttg gacagtcggt caccatctcc
      121 tgcactggaa ccagcagtga cattggtggt tataatgacg tctcctggta ccaccagcac
      181 gcaggcacag cccccagact cctgatttat gatgtcagta agcggccctc aggggtctct
      241 gatcgcttct ctggctccaa gtctggcaac acggcctccc tggccatctc tgggctccag
      301 gctgaggacg aggctgatta ttactgctgc tcatatagga gtggaaacac ttatgtgttc
      361 ggaagtggca ccaagttgac cgtcctcggt cagcccaagg cttccccctt ggtcactctg
      421 ttcccg
//
LOCUS       KCVO01001501             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:20135:6546
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001501
VERSION     KCVO01001501.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:20135:6546"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73530.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       410..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           89 a          157 c          128 g          110 t
ORIGIN      
        1 acatggggct ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct cctctcctcc tcacccttct cattcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagtgtctgg ggcgcccggg cagagggtca ccatctcctg
      181 cactgggagc agttccaaca ttggaggtta ttatgtgcag tggtaccagc agcttccagg
      241 aacggccccc aaactcctca tgtatgaaaa taataagcga ccctcagggg tttctgatcg
      301 attctctggc tcccagtctg gtacctcagc ctccctgacc atcactggac tccagtctga
      361 ggatgaggct gattattact gccagtccta tgacagcagc ctgagtgccg tgttattcgg
      421 agcagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCVO01001502             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:3944:13233
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001502
VERSION     KCVO01001502.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:3944:13233"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..420
                     /note="immunoglobulin light chain variable region"
     V_region        101..420
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73531.1"
                     /translation="DYYCYSTDTSAYHVF"
     J_segment       389..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>460
                     /gene="IGLC"
BASE COUNT           91 a          140 c          124 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagg tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac actaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggtc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttattcaaca gatactagtg cttatcatgt attcggcgga gggacccggc tgaccgtcct
      421 gggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001503             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:22176:7887
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001503
VERSION     KCVO01001503.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22176:7887"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73532.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       375..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           91 a          143 c          116 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct ctgagctgac acagccaccc tcggtgtcag
      121 tgtcccccgg acagacggcc aggatcacct gctctggaaa tgcattgcca aaatactatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtggc gatcatctat gaggacaaca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtagaggatg aggctgacta ctactgttac tcaacagata
      361 gcagtggtac taatggctta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001504             506 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:15325:20197
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001504
VERSION     KCVO01001504.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 506)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 506)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..506
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15325:20197"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    138..468
                     /note="immunoglobulin light chain variable region"
     V_region        138..468
     V_segment       138..431
                     /gene="IGLV8-111"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <396..>440
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73533.1"
                     /translation="DYYCAVYMGSGIDVF"
     J_segment       432..468
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        469..>506
                     /gene="IGLC"
BASE COUNT          103 a          156 c          131 g          116 t
ORIGIN      
        1 acatggggga aaaggccctg aggaaaacaa actccagctg agaagcctga gagcacttgg
       61 ccttcataag tgtccccacc atggcctgga tgatgcttct cctcggactc cttgcttatg
      121 gctcaggagt ggattctgag actgtggtga cccaggagcc atcgttgtca gtgtcccctg
      181 gaggaacagt cacactcacc tgtggcctga gctctggctc agtctctacc gataactacc
      241 ccagctggta ccagcagacc ccaggccagg ctccacgcat gctcctcttc aacacaaaca
      301 ctcgcccttc tggggtccct actcgcttct ctggctccat ccttgggaac aaagctgccc
      361 tcaccgtcac gggggctcag gcagacgatg aatctgatta ttactgtgcg gtgtacatgg
      421 gtagtggcat tgatgtgttc ggaagtggca ccaagttgac cgtcctcggt cagcccaagg
      481 cttccccctt ggtcactctg ttcccg
//
LOCUS       KCVO01001505             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:18632:10763
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001505
VERSION     KCVO01001505.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18632:10763"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..453
                     /note="immunoglobulin light chain variable region"
     V_region        120..453
     V_segment       120..413
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73534.1"
                     /translation="DYYCLSYDSSLSTHYIF"
     J_segment       416..453
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           97 a          166 c          119 g          109 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctc gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacacagcca ccctcagtgt ctggggcccc agggcagagg gtcaccatct
      181 cgtgcactgg gagcagctcc agcattggag gtgattatgt atcctggtac caacagctcc
      241 caggaacgac ccccaaactc ctcatctatc aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtacct cagcctccct gaccatcact gggctccaga
      361 ctgaggatga ggctgattac tactgcctgt cctatgacag cagcctgagt actcattaca
      421 tcttcggtcc tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca
      481 ctctgttccc g
//
LOCUS       KCVO01001506             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:16361:12154
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001506
VERSION     KCVO01001506.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16361:12154"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    73..289
                     /note="immunoglobulin light chain variable region"
     V_region        73..289
     V_segment       73..250
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <214..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73535.1"
                     /translation="DYYCYSIDSSGNLSVF"
     J_segment       257..289
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>327
                     /gene="IGLC"
BASE COUNT           61 a          105 c           85 g           76 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacagaagcc aggccagtcc cctgtgctga tcatctatga ggacactaaa
      121 cggccctctg ggatccctga gagattctct ggctccagct cagggacagt ggccaccttg
      181 actatcagtg gggcccaggt ggcggatgaa gctgactact actgttactc aatagatagc
      241 agtggtaatc tgagcgtctt cggtgctggg acccggctca ccgtcctagg tcagcccaag
      301 gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01001507             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:17762:12801
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001507
VERSION     KCVO01001507.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17762:12801"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..404
                     /gene="IGLV5-65"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73536.1"
                     /translation="DYYCAIWHSSASYIF"
     J_segment       405..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           92 a          162 c          112 g          113 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgacccag ccaacctccc
      121 tctcagcatc tccgggagca tcagccagac tcagctgcac cttgagcagt ggcatcaatg
      181 ttggtactta cagcatattc tggtaccagc agaagccagg gagtcctccc cggtaccttc
      241 tgtacttcta ctcagactca cgtaaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaagga tgcttcagcc aatgcaggcc ttttaatgat ctctgggctc cagtctgaag
      361 atgaggctga ctattactgt gccatatggc acagcagcgc ttcttacatc ttcggtggtg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001508             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:21691:11499
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001508
VERSION     KCVO01001508.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21691:11499"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73537.1"
                     /translation="DYYCYSTDSSGNGLF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           96 a          141 c          124 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tccaatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tttgcttatt ggtaccagca gaaaccaggc cagtcccctg tgctgatcat
      241 gtatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccacctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gacagcagtg gtaatggctt attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001509             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:23134:4479
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001509
VERSION     KCVO01001509.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:23134:4479"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..453
                     /note="immunoglobulin light chain variable region"
     V_region        120..453
     V_segment       120..411
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73538.1"
                     /translation="NYYCLSSDTSLSGHGLF"
     J_segment       416..453
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           94 a          164 c          123 g          110 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 acatggcctc gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacacagcca ccctcactgt ctggggcccc agggcagagg gtcaccatct
      181 cgtgcactgg gagcagctcc aacattggag gttattctgt atcctggtgc cagaagttcc
      241 cagaaacgac ccccaacctc ctcgactatc aagataataa gcgaccctca ggggtttctg
      301 cccgattctc tggctccaag tctggtccct tagcctccct gaccatcact gggctccaga
      361 ctgaggatgg gactaattat tactgcctgt cgtctgacac cagcctgagt ggtcatggct
      421 tattcggagg aggaacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      481 ctctcttccc g
//
LOCUS       KCVO01001510             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:26992:19451
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001510
VERSION     KCVO01001510.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:26992:19451"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73539.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       379..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           91 a          139 c          117 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaagtatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaagacgaca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aaggtgacta ctactgttac tcaatagaca
      361 gtagtggtag tcatagcgtc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001511             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:22762:4562
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001511
VERSION     KCVO01001511.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22762:4562"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73540.1"
                     /translation="DYYCYSTDSSTNHGLF"
     J_segment       393..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           97 a          144 c          124 g          102 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatt gcctggattc
       61 ctctcctact ccccctcctc actttctgca caggctctgc agcctcctat gagctgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg
      181 cattgccaaa aaaatatgct tgttggttcc agcagaagcc aggccagtcc cctgtaatga
      241 tcatctatga ggacagcaaa cggccccctg ggatccctga gagattctct ggctccagct
      301 cagggacagt ggccaccttg actatcagtg gggcccaggt ggaggatgaa gctgactact
      361 actgttactc aacagatagc agtactaatc atggcttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001512             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:20651:4049
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001512
VERSION     KCVO01001512.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20651:4049"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73541.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           86 a          154 c          123 g          110 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tatacaagca gtagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001513             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:16918:10996
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001513
VERSION     KCVO01001513.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:16918:10996"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..430
                     /note="immunoglobulin light chain variable region"
     V_region        100..430
     V_segment       100..393
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73542.1"
                     /translation="DYYCGAWDSSLSTRLF"
     J_segment       395..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           90 a          152 c          124 g          102 t
ORIGIN      
        1 acatgggggg cacaggaggc agcactcagg acagtctcca gcatggcctg gtctcctctc
       61 ctcctcaccc ttctcattca ctgcacaggg tcctgggccc agtctgtgct gacgcagccg
      121 ccctcagtgt ctggggaccc cgggcagagg gtcaccatct cgtgcactgg gagcagctcc
      181 aacattggag gttattttgt atactggtac cagcagttcc caggaacagc ccccaaactc
      241 ctcatctatg acaataataa gcgaccctca gggatttctg accgattctc tggctccaag
      301 tctggtacct cagcctccct gaccatcact gggctccagc ctggggatga ggctgattat
      361 tactgcggag catgggatag cagcctgagt actcgcttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001514             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:15020:12304
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001514
VERSION     KCVO01001514.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15020:12304"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73543.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          162 c          125 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ccactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001515             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:21763:10102
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001515
VERSION     KCVO01001515.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:21763:10102"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73544.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           91 a          141 c          117 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagcctccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatctcct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag gcaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ttcagggaca atggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagata
      361 acagtgatac tcataggggc ttcttcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001516             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:14892:5937
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001516
VERSION     KCVO01001516.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:14892:5937"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73545.1"
                     /translation="DYYCQVWDSTSDHSIF"
     J_segment       399..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          148 c          134 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagtctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggggaca
      181 acattggaac tgaatatgtg cactggtacc agcagaagcc accgcaggcc cctgtggtgg
      241 tcatctatta taatactgac cggccctcag ggatccctga gcgattctca ggctccaaat
      301 cagggaacac cggcaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt actagtgatc attccatttt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01001517             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:7957:10914
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001517
VERSION     KCVO01001517.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7957:10914"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73546.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       399..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          145 c          134 g           99 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tctccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaga taaatattta cactggtacc accagaagcc agcgcaggcc cctgtgctgg
      241 tcatctacta tgatagtgac cggccctcat ggatccctga gcgattctct gggtccaagt
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt aataatgatc atatcttttt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001518             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:11661:12496
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001518
VERSION     KCVO01001518.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:11661:12496"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..426
                     /note="immunoglobulin light chain variable region"
     V_region        104..426
     V_segment       104..385
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73547.1"
                     /translation="DYYCQVWDSSSDHWVF"
     J_segment       391..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>466
                     /gene="IGLC"
BASE COUNT           84 a          145 c          144 g           93 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactgcac aggctctgcg gtctcctatg agctgactca
      121 gccacgatca gtgtccgtgt ccccaggaca gacggcccgg atcacctgtg ggggagacaa
      181 cattggaagt aaaagtgtgc agtggttccg gcagaagcca ccgcaggccc ctgtgctggg
      241 catttatggt gatagcgaac ggccctcagg gatccctgag cgattctctg actccaactc
      301 agggaacacc gccaccctga ctatcagcgg ggtcgaggcc gggaatgagg ctgactatta
      361 ctgtcaggtg tgggacagta gtagtgatca ttgggtattc ggcggaggga cccggctgac
      421 cgtcctcggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001519             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:12076:17887
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001519
VERSION     KCVO01001519.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12076:17887"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73548.1"
                     /translation="DYCCQVWDSSGDVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          140 c          140 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 ccattggaag tagaagtgtg cagtggtacc agcagaagtc atcgcaggcc cttgtactgg
      241 tcatctatgc taatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 gctgtcaggt gtgggacagt agtggtgatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001520             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:19053:17500
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001520
VERSION     KCVO01001520.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:19053:17500"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73549.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          161 c          124 g          108 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct aactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catatactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtactggagt gttgttcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01001521             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:14892:3579
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001521
VERSION     KCVO01001521.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:14892:3579"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73550.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          161 c          123 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcagtc actctcttcc
      481 cg
//
LOCUS       KCVO01001522             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:19916:10310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001522
VERSION     KCVO01001522.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19916:10310"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73551.1"
                     /translation="DYYCAAWDDSLNSPFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           91 a          155 c          114 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaac
      181 attggaagta attatgtaaa ctggtaccag caactcccag gaacggcccc caaactcctc
      241 atctatttta ctaatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcggcat gggatgacag cctgaacagt cccttcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001523             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:12041:13055
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001523
VERSION     KCVO01001523.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12041:13055"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73552.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           98 a          143 c          121 g           98 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgtagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggtaccagca gaaaccaggc cagtccccta tgctgatcat
      241 ctatgaggac aacaaacggc cctctgggat ccctgaaaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacaacagtg gtcagggctc attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001524             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:10957:17693
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001524
VERSION     KCVO01001524.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10957:17693"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73553.1"
                     /translation="DYFCSSYTSSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          155 c          124 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattatttc tgcagctcat acacaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001525             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:24797:10791
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001525
VERSION     KCVO01001525.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:24797:10791"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..404
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73554.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       406..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           87 a          156 c          130 g          107 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcggcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacattgg aggttattat gtgcagtggt accagcagct tccaggaacg
      241 gcccccaaac tcctcatgta tgaaaataat aagcgaccct caggggtttc tgatcgattc
      301 tctggctccc agtctggtgc ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgcca gtcctatgac agcagcctga gtgccgtgtt attcggagca
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001526             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:11392:17924
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001526
VERSION     KCVO01001526.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11392:17924"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73555.1"
                     /translation="DYYCSSYATSSTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          157 c          122 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcaga ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtggtt ttaaccgtgt ctcctggtac caacaacacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtaa tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacgcaac cagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001527             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:12987:14936
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001527
VERSION     KCVO01001527.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12987:14936"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73556.1"
                     /translation="DYHCFSTDSSGNHRGIF"
     J_segment       396..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           94 a          145 c          126 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgacgac agcaaacggc cctctgggat ccctgagaga gtctctggct ccagctcagg
      301 gacagtggcc accttgacta tcattggggc ccaggtggag gatgaagctg actaccactg
      361 tttctcaaca gatagcagtg gtaatcatag gggcatattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001528             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:13718:14773
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001528
VERSION     KCVO01001528.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:13718:14773"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73557.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           95 a          160 c          120 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcacttgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcac ctccaacatc ggaactaata gtgtatcctg gtaccagcag ctcccagaaa
      241 cggctcccaa actcctcatc tattataatg atcgacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg ataacagcct gagcggttac atcttcggtg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCVO01001529             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:21590:21104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001529
VERSION     KCVO01001529.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:21590:21104"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73558.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          144 c          126 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgacgac agcaaacggc cctctgggat ccctgagaga tgctctggct ccagctcagg
      301 gacagtggcc accttgacta tcattggggc ccaggtggag gatgaagctg actaccactg
      361 tttctcaaca gatagcagtg gtaatcatag gggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001530             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:7736:8021
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001530
VERSION     KCVO01001530.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:7736:8021"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73559.1"
                     /translation="DYYCQVWDSSSDHPIF"
     J_segment       395..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          144 c          136 g          100 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtttcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acgttggaag tgaatatgtg cactggtatc agcagaagtc agcgcaggcc cctgtggtgg
      241 tcatctatta ttatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtagaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc atcccatctt cggtactggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01001531             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:6403:13670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001531
VERSION     KCVO01001531.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:6403:13670"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..431
                     /note="immunoglobulin light chain variable region"
     V_region        108..431
     V_segment       108..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73560.1"
                     /translation="DYFCCSHADTYTFVF"
     J_segment       408..431
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>476
                     /gene="IGLC"
BASE COUNT           83 a          158 c          123 g          112 t
ORIGIN      
        1 acatgggggg ctggggtctc agacggcagc gctctcggga catctccacc atggcctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccctga
      121 ctcagcctcg ctcagtgtct gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga catcggtggt tataactttg tctcctggta ccaacaacat ccaggcacag
      241 cccccaaact catgatttat gaggtcaatc agcggccctc aggggtctct gatcgcttct
      301 ctggctcaaa gtctggcaac acggcctccc tgaccgtctc cggggtccag gctgaggacg
      361 aggctgatta tttctgctgc tcacatgcag acacctacac ttttgttttc ggaagtggca
      421 ccaggttgac cgtcgtcggt cagcccaagg cttccccctt ggtcactctg ttcccg
//
LOCUS       KCVO01001532             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:21516:3785
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001532
VERSION     KCVO01001532.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21516:3785"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73561.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           87 a          153 c          123 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagtacccag gcaaagcccc
      241 caaagtcatc atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttcactgg
      301 tttcaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001533             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:5875:12099
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001533
VERSION     KCVO01001533.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:5875:12099"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..447
                     /note="immunoglobulin light chain variable region"
     V_region        114..447
     V_segment       114..407
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73562.1"
                     /translation="DYYCSLWDSRLSSRVF"
     J_segment       412..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           92 a          155 c          128 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccgggca gagggtcacc atctcctgca
      181 ctgggaccag ctccaacatc ggggcgaatt attatgtttc ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctatgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catctctgga ctccaatctg
      361 aggatgaggc tgattattat tgctcactat gggatagcag gctgagtagt cgggtattcg
      421 gcggagggac ccgactgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001534             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:25224:17546
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001534
VERSION     KCVO01001534.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:25224:17546"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73563.1"
                     /translation="DFYCYSRDSSENQSVF"
     J_segment       393..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           98 a          138 c          123 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgtatatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac aacaaacggc cctctgggat tcctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaaggtg acttctactg
      361 ttactcaaga gatagtagtg aaaatcaaag cgtcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001535             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:12522:17573
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001535
VERSION     KCVO01001535.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12522:17573"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73564.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          144 c          138 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctcactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggaggca
      181 atgttggaag tgaatatgtc cactggtatc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatctatta taatactgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt aggagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001536             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:23827:18251
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001536
VERSION     KCVO01001536.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:23827:18251"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..443
                     /note="immunoglobulin light chain variable region"
     V_region        114..443
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73565.1"
                     /translation="DYFCAVWDDSLSGVLF"
     J_segment       408..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>482
                     /gene="IGLC"
BASE COUNT           90 a          154 c          128 g          110 t
ORIGIN      
        1 acatggggga gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcctcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggat gagtgtcacc atctcctgtt
      181 ctggaagcac ctccaacatc ggaagtaaca gtgtgtcctg gtacctgcag ctcccggaaa
      241 cggctcccaa actcctcatc tattataatg atcggcgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc ccgtcagcct ccctggccat cagtgggctc gagaccgaag
      361 atgaggctga ttatttctgc gcagtatggg atgatagcct gagcggtgtg ttattcggag
      421 gagggacccg actgaccgtc ctaagtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001537             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:9849:3542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001537
VERSION     KCVO01001537.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:9849:3542"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73566.1"
                     /translation="DYYCYSTDNSGTHRGFF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           94 a          143 c          127 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaagcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaaggcaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagttcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gataacagtg gtactcatag gggcttcttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001538             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:5643:13509
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001538
VERSION     KCVO01001538.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:5643:13509"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73567.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           98 a          144 c          121 g           97 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggtaccagca gaaaccaggc cagtccccta tgctgatcat
      241 ctatgaggac aacaaacggc cctctgggat ccctgaaaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacaacagtg gtcagggctc attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001539             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:13800:13511
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001539
VERSION     KCVO01001539.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:13800:13511"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..445
                     /note="immunoglobulin light chain variable region"
     V_region        117..445
     V_segment       117..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73568.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       411..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>485
                     /gene="IGLC"
BASE COUNT           86 a          160 c          130 g          109 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggcggtt attatgtgca gtggtaccag cagcttccag
      241 gagcggcccc caaactcctc atgtatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggtacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cctgagtgcc gtgttattcg
      421 gaccagggac ccggctgacc gtcctgggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001540             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:2221:11178
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001540
VERSION     KCVO01001540.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:2221:11178"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73569.1"
                     /translation="DYYCQSYDSSLSAVFF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          158 c          126 g          111 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cacctccaat attggagatt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc cagactcctc atctatgaaa ataataaacg accctcaggg atttctgatc
      301 gattctctgg ctcccagtct ggtacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cctgagtgcc gtgtttttcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001541             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:6840:14120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001541
VERSION     KCVO01001541.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:6840:14120"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..406
                     /note="immunoglobulin light chain variable region"
     V_region        87..406
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73570.1"
                     /translation="DYYCYSTDTSAYHVF"
     J_segment       375..406
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>446
                     /gene="IGLC"
BASE COUNT           90 a          139 c          117 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acaggcaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagta
      241 aacggccctc tgggatccct gagagaatct ctggctccag ctcagggaca gtggtcacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagata
      361 ccagtgctta tcatgtattc ggcggaggga cccggctgac cgtcctgggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001542             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:13161:4663
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001542
VERSION     KCVO01001542.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:13161:4663"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..422
                     /note="immunoglobulin light chain variable region"
     V_region        104..422
     V_segment       104..385
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73571.1"
                     /translation="DYYCQSTDSSGYIF"
     J_segment       386..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT          102 a          135 c          119 g          104 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgtg gcctcctatg agctgacaca
      121 gccaccttca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actgacaaaa aattatgctc agtggttcca gcagaagcca ggccaggccc ctgtgctgct
      241 gatatataaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaaca gttaccttga ccatcagtcg ggcccaggta gaagatgagg ctgactatta
      361 ttgtcaatca acagacagca gtggttacat cttcggtgct gggacccggc tcaccgtcct
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01001543             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:21024:10595
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001543
VERSION     KCVO01001543.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:21024:10595"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73572.1"
                     /translation="DYYCYSTRGSGYHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          142 c          123 g          106 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccagac cagtcccctg tgctgatcat
      241 ctatgaggac accaaacggc cctctgggat ctctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtgcag gatgaagctg actactactg
      361 ttactcaact cgtggcagtg gttatcatgg cttattcgga ggagggactt ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001544             310 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:13169:14130
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001544
VERSION     KCVO01001544.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 310)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 310)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:13169:14130"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..271
                     /note="immunoglobulin light chain variable region"
     V_region        8..271
     V_segment       8..230
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <194..>244
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73573.1"
                     /translation="NYYCLSYDTSLSGHGLF"
     J_segment       235..271
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        272..>310
                     /gene="IGLC"
BASE COUNT           65 a           97 c           77 g           71 t
ORIGIN      
        1 acatgggggg agcagctcca acattggagg ttattctgta tcctggtgcc agaagttccc
       61 agaaacgacc cccaacctcc tcgactatca agataataag cgaccctcag gggtttctga
      121 ccggttctct ggctccaagt ctggtccctc agcctccctg accatcactg ggctccagac
      181 tgaggatggg actaattatt actgcctgtc gtatgacacc agcctgagtg gtcatggctt
      241 attcggagga ggaacccggc tgaccgtcct aagtcagccc aaggctgccc cctcggtcac
      301 tctcttcccg
//
LOCUS       KCVO01001545             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:17677:8328
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001545
VERSION     KCVO01001545.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:17677:8328"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73574.1"
                     /translation="DYYCYSSDSSADYWVF"
     J_segment       387..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>461
                     /gene="IGLC"
BASE COUNT           90 a          141 c          127 g          103 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 cagaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgtg ttgatcatct
      241 atgaggacag caaacggccc tctgggatcc ctgagagatt ctctggttcc agctcaggga
      301 cagtggccac cttgactatc agtggggccc aggtggagga tgaagctgac tactactgtt
      361 actcatcaga tagcagtgct gattattggg tgttcggcgg agggacccgg ctgaccgtcc
      421 caggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001546             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:11303:4382
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001546
VERSION     KCVO01001546.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11303:4382"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73575.1"
                     /translation="DYYCQVWDSNSDVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          139 c          141 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagattctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcgttggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttgtactgg
      241 tcatctatgc tgatagggaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt aatagtgatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001547             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:8839:14082
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001547
VERSION     KCVO01001547.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:8839:14082"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73576.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           91 a          140 c          117 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gagagaatct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gtagtggtaa tcatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001548             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:23634:6243
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001548
VERSION     KCVO01001548.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:23634:6243"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    126..447
                     /note="immunoglobulin light chain variable region"
     V_region        126..447
     V_segment       126..413
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73577.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       414..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           97 a          149 c          134 g          105 t
ORIGIN      
        1 acatggggga agcctaggga gcccagctgt gctgtgggct caggaggcag agctctgggt
       61 gtctcaccat ggcctggatt cctctcctac tccccctcct cactttctgc acaggctctg
      121 cagcctccta tgagctgaca cagccaccct cggtgtcagt gtccccagga cagacggcca
      181 ggatcacctg ctctggagat gcattgccag aaaaatttgc ttattggttc caacagaagc
      241 caggccagtc ccctgtgctg atcatcaatg aggacagcaa acggccctct gggatccctg
      301 agagattctc tggctccagc tcagggacag tggccacctt gactctcagt ggggcccagg
      361 tggaggatga aggtgactac tactgttcct caacagatag cagtggtaat tatgtattcg
      421 gcggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001549             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:9009:14506
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001549
VERSION     KCVO01001549.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9009:14506"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73578.1"
                     /translation="DYYCHLYDSSGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          161 c          124 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcact tgtatgacag tagtggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001550             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:19834:8725
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001550
VERSION     KCVO01001550.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:19834:8725"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..426
                     /note="immunoglobulin light chain variable region"
     V_region        97..426
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73579.1"
                     /translation="DYYCATWDDSLSGRIF"
     J_segment       397..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>465
                     /gene="IGLC"
BASE COUNT           90 a          153 c          120 g          102 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcctc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cagctccaat
      181 atcggaagta atactgtgtc ctggtaccag cagctcccag gaacggctcc caaactcctc
      241 atctattata atgatcggcg agcctcaggt gtctctgacc gattctctgc ctccaagtct
      301 ggcacgtcag cctccctggc catcagtggg ctccagaccg aggatgaggc tgattattac
      361 tgcgcaacat gggatgatag cctgagcggt cggattttcg gcggagggac ccggctgacc
      421 gtcctaagtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001551             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:10956:18748
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001551
VERSION     KCVO01001551.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10956:18748"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..436
                     /note="immunoglobulin light chain variable region"
     V_region        107..436
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73580.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       402..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>475
                     /gene="IGLC"
BASE COUNT           85 a          162 c          120 g          108 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtggc attggtagtt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg acgtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacgcaag cactaccact tggctattcg gcggagggac
      421 ccgcctgacc gtcctacgtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001552             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:20914:6504
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001552
VERSION     KCVO01001552.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:20914:6504"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73581.1"
                     /translation="DYYCYSTRSSGYYGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          141 c          123 g          106 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ctctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtgcaa gatgaagctg actactactg
      361 ttactcaact cgtagcagtg gttattatgg cttattcgga ggagggacct ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001553             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:22178:4966
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001553
VERSION     KCVO01001553.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22178:4966"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73582.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       379..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           99 a          132 c          117 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 tatattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatgtat gaggacaaca
      241 aacggccctc tgggatacct gagagaatct ctggttccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aaggtgacta ctactgttac tcaagagata
      361 gtagtgaaaa tcaaagcgtc ttcggtgctg ggacccggtt cagcgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001554             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:10605:19393
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001554
VERSION     KCVO01001554.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10605:19393"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..431
                     /note="immunoglobulin light chain variable region"
     V_region        110..431
     V_segment       110..397
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73583.1"
                     /translation="DYYCYSSESSADYWVF"
     J_segment       398..431
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>472
                     /gene="IGLC"
BASE COUNT           92 a          143 c          130 g          107 t
ORIGIN      
        1 acatggggag ctgtgctgtg ggctcaggag gcagagctct gggtgtctca ccatggcctg
       61 gattcctctc ctactccccc tcctcacttt ctgcacaggc tctgcagcct cctatgagct
      121 gacacagcca ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg
      181 agatgcattg ccagaaaaat atgcttattg gttccagcag aagccaggcc agtcccctgt
      241 gttgatcatc tatgacgaca gcaaacggcc ctctgggatc cctgagagat tctctggttc
      301 cagctcaggg acagtggcca ccttgactat cagtggggcc caggtggagg atgaagctga
      361 ctactactgt tactcatcag aaagtagtgc tgattattgg gtgttcggcg gagggacccg
      421 gctgaccgtc ccaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001555             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:11985:15828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001555
VERSION     KCVO01001555.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11985:15828"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73584.1"
                     /translation="DYYCQVYDSSANMFF"
     J_segment       412..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          159 c          125 g          112 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg gagtaagaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca aagagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaggtaata cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tagtgctaat atgtttttcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001556             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:22445:8628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001556
VERSION     KCVO01001556.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:22445:8628"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    128..455
                     /note="immunoglobulin light chain variable region"
     V_region        128..455
     V_segment       128..415
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73585.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       419..455
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT          100 a          150 c          136 g          107 t
ORIGIN      
        1 acatgggaga gaagcctagg gagcccagct gtgctgtggg ctcaggaggc agagctctgg
       61 gtgtctcacc atggcctgga ttcctctcct actccccctc ctcactttct gcacaggctc
      121 tgcagcctcc tatgagctga cacagccacc ctcggtgtca gtgtccccag gacagacggc
      181 caggatctcc tgctctggag atgcattgcc aaaaaaattt gcttcttggt tccagcagaa
      241 ggcaggccag tcccctgtgc tgatcatcta tgaggacagc aaacggccct ctgggatccc
      301 tgagagattc tgtggctcca gctcagggac agtggccacc ttgactatca gtggggccca
      361 ggtggaggat gaagctgact actactgtta ctcaacagat aacagtgata ctcatagggg
      421 cttcttcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCVO01001557             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:19784:13462
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001557
VERSION     KCVO01001557.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19784:13462"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73586.1"
                     /translation="DYYCSSYASSSTWIF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           89 a          156 c          121 g          106 t
ORIGIN      
        1 acatgggggg gatctcagga ggcaacactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcata atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcag tagcacttgg atattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001558             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:17529:11791
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001558
VERSION     KCVO01001558.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:17529:11791"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73587.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          158 c          121 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgtttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac taccacttgg ctattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001559             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:16950:7316
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001559
VERSION     KCVO01001559.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:16950:7316"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73588.1"
                     /translation="EYYCSSYAGSYTLVF"
     J_segment       404..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           81 a          159 c          123 g          112 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagttggtc accatctcct gcattggaac
      181 cagcagtgac atcggtgctt atgactatgt ctcctggtac caacagcatc caggcacagc
      241 ccccaaactc atgatttttg aggtcagtga gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctgccaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgagtat tactgttcct catatgcagg cagctacact ctcgtgttcg gaagtggcac
      421 caagttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001560             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:18938:9419
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001560
VERSION     KCVO01001560.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18938:9419"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73589.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           84 a          156 c          120 g          112 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggaacttata actatgtctc ctggtaccaa cagcatccag gcacagcccc
      241 caaactcatg atttttgagg tcagtgagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgttgctcat atgcagacac ctacactttt gtgtttggag gtggcaccag
      421 attgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01001561             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:15985:5020
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001561
VERSION     KCVO01001561.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:15985:5020"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73590.1"
                     /translation="EYYCSSYADIYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          161 c          119 g          110 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tggcctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcacgggcac
      181 cagcagtgac atcggtggtt acaactttgt ctcctggtac caacaccatc cagacacagc
      241 ccccaaactc gtgatttatg aggtcactca gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatttct gggctccagg ctgaggacga
      361 ggctgaatat tactgcagtt catatgcaga catctacaca tttgtgttcg gaagtggcac
      421 caagttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001562             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:23357:13464
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001562
VERSION     KCVO01001562.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:23357:13464"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73591.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       402..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           86 a          155 c          124 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagtt catacacaag cagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001563             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:18274:17220
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001563
VERSION     KCVO01001563.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:18274:17220"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73592.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          161 c          119 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtacttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcgacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001564             306 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:7681:12584
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001564
VERSION     KCVO01001564.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 306)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7681:12584"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    5..268
                     /note="immunoglobulin light chain variable region"
     V_region        5..268
     V_segment       5..228
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>240
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73593.1"
                     /translation="DYYCLSYDSSLSAHYIF"
     J_segment       231..268
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        269..>306
                     /gene="IGLC"
BASE COUNT           66 a           99 c           70 g           71 t
ORIGIN      
        1 acatggggca gctccagaat tggaggtgat tatgtatcct ggtaccaaca gctcccagga
       61 aaggccccca aactcctcat ctatcaaaat aataagcgac cctcaggggt ttctgaccga
      121 ttctctggct ccaagtctgg tacctcagcc tccctgacca tcactgggct ccagactgag
      181 gatgaggctg attactactg cctgtcctat gacagcagcc tgagtgctca ttacatcttc
      241 ggtcctggga cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg
      301 ttcccg
//
LOCUS       KCVO01001565             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:10311:18942
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001565
VERSION     KCVO01001565.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10311:18942"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73594.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       379..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           97 a          136 c          115 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 tatattggtt ccagcagaag ccaggccagt cccctctgtt gatcatctat gaggacaaca
      241 aacggccctc tgggattcct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aaggtgacta ctactgttac tcaagagata
      361 gtagtgaaaa tcaaagcgtc ttcggtgctg ggacccggct cagcgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001566             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:7571:7998
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001566
VERSION     KCVO01001566.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7571:7998"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73595.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          143 c          138 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcattggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttctactgg
      241 tcatctatgc tgataccgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001567             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:9631:13376
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001567
VERSION     KCVO01001567.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:9631:13376"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73596.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       394..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          141 c          140 g           96 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgac ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaatg
      181 ttggaagtga atatgtgcac tggtaccaac agaagccagc gcaggcccct gtggtggtca
      241 tccattataa tagtgaccgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatcatt gtgtattggg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001568             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:12225:19306
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001568
VERSION     KCVO01001568.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:12225:19306"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73597.1"
                     /translation="DYYCSSTDSSGSYVF"
     J_segment       387..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           91 a          143 c          125 g           99 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 cagaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgta ctgatcatca
      241 atgaggacag caaacggccc tctgggatcc ctgggagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactctc agtggggccc aggtggagga tgaagctgac tactactgtt
      361 cctcaacaga cagtagtggt agttatgtat tcggcggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001569             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:21880:15831
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001569
VERSION     KCVO01001569.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:21880:15831"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73598.1"
                     /translation="EYYCSSYADIYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          162 c          119 g          109 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tggcctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcacgggcac
      181 cagcagtgac atcggtggtt acaactttgt ctcctggtac caacaccatc cagacacagc
      241 ccccaaactc gtgatttatg aggtcactca gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgaatat tactgcagtt catatgcaga catctacaca tttgtgttcg gaagtggcac
      421 caagttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001570             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:17137:19776
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001570
VERSION     KCVO01001570.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:17137:19776"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..424
                     /note="immunoglobulin light chain variable region"
     V_region        102..424
     V_segment       102..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73599.1"
                     /translation="DYYCYSSDISGNHRVF"
     J_segment       391..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>464
                     /gene="IGLC"
BASE COUNT           94 a          140 c          125 g          105 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccaaaaaa atatgcttat tggttccagc agaagccagg ccagtcccct gtgctgatca
      241 tctatgaaga cagtaaacgg ccctctggga tccctgagag attctctggc tccagttcag
      301 ggacagtggc caccttgact atcagtgggg cccaggtgga ggatgaagct gactactact
      361 gttactcatc agatatcagt ggtaatcata gggtattcgg cggagggacc cggctgaccg
      421 tccttggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001571             306 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:7089:17792
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001571
VERSION     KCVO01001571.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 306)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7089:17792"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..268
                     /note="immunoglobulin light chain variable region"
     V_region        7..268
     V_segment       7..231
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <193..>240
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73600.1"
                     /translation="DYYCQSYDTRLRAWVF"
     J_segment       232..268
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        269..>306
                     /gene="IGLC"
BASE COUNT           66 a           93 c           76 g           71 t
ORIGIN      
        1 acatggggga gcagctccaa cattggagat tattttgtgc agtggtacca acagcttcca
       61 ggaacggccc ccaaactcct catctatgaa aatgataaac ggccctcagg agtttctgat
      121 cgattctctg gctcccagtc tggaacctca gcctccctca ccatcactgg actccagtct
      181 gaggatgagg ctgattatta ctgccagtcc tatgacacca gattgagggc ttgggtattc
      241 ggcggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      301 ttcccg
//
LOCUS       KCVO01001572             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:23328:13840
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001572
VERSION     KCVO01001572.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:23328:13840"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..420
                     /note="immunoglobulin light chain variable region"
     V_region        102..420
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73601.1"
                     /translation="DYYCQVWDSSSDHRIF"
     J_segment       396..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>464
                     /gene="IGLC"
BASE COUNT           84 a          143 c          140 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gttttgcggt ctcctatgag ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaacc
      181 ttggaagtaa atatgtacac tggtaccagc agaagccagc gcaggcccct gtggtggtca
      241 tctattatga tagtgaccgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggagcaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatcatc ggattttcgg cggagggacc cggctgaccg
      421 cccttggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001573             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:23086:11076
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001573
VERSION     KCVO01001573.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:23086:11076"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73602.1"
                     /translation="DYYCQSAESSGDHYIF"
     J_segment       389..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          105 a          138 c          122 g           98 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatgctcagt ggttccacca gaagccaggc caggcccctg tgctggtgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga atctctagct ccagttcagg
      301 gacaacagtt accttgacca tcactggggc ccaggcagaa gatgaggctg actactactg
      361 tcaatcagca gagagcagtg gtgatcatta catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001574             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:8595:18649
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001574
VERSION     KCVO01001574.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8595:18649"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73603.1"
                     /translation="DYYCYSSDSSANYWVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           92 a          141 c          124 g          106 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg ttttgatcat
      241 ctttgaggac agcaaacggc cctctgggat ccctgagaga ttctctggtt ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcatca gatagcagtg ctaattattg ggtattcggc ggagggaccc ggctgaccgt
      421 cccaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001575             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:12018:21015
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001575
VERSION     KCVO01001575.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:12018:21015"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73604.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          163 c          119 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc ctttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa caccacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctccggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac ttccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001576             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:10935:19287
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001576
VERSION     KCVO01001576.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:10935:19287"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73605.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          160 c          118 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacga cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001577             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:17851:14010
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001577
VERSION     KCVO01001577.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:17851:14010"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73606.1"
                     /translation="DYYCSSYTSSSTWIF"
     J_segment       400..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           86 a          155 c          123 g          109 t
ORIGIN      
        1 atgggggctg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca gtagcacttg gatattcggc ggagggaccc
      421 ggctgaccgt ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001578             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:18131:6652
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001578
VERSION     KCVO01001578.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:18131:6652"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73607.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       393..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           94 a          146 c          125 g          102 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccctcctc actttctgca caggctctgc agcctcctct gacctgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg
      181 cattgccaaa atactatgct tattggttcc agcagaagcc aggccagtcc cctgtggcga
      241 tcatctatga ggacaacaaa cggccctctg ggatccctga gagattctct ggctccagct
      301 cagggacagt ggccaccttg actatcagtg gggcccaggt agaggatgaa gctgactact
      361 actgttactc aacagatagc agtggtacta atggcttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001579             413 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:13986:16644
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001579
VERSION     KCVO01001579.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 413)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13986:16644"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..400
                     /note="immunoglobulin light chain variable region"
     V_region        101..400
     V_segment       101..383
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73608.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       391..400
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        401..>413
                     /gene="IGLC"
BASE COUNT           85 a          121 c          112 g           95 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctttg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg cactgttcat
      241 ctatgaggat agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccagggggag gatgaagctg actactactg
      361 ttattcaatg gatagcagtg gtacgcagag catcttcggt cactctgttc ccg
//
LOCUS       KCVO01001580             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:6605:11506
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001580
VERSION     KCVO01001580.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:6605:11506"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73609.1"
                     /translation="DYYCQVWDSRSDHYIF"
     J_segment       393..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          143 c          137 g          101 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctgattc
      121 agtcaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaag taattctgtg cactggtacc agcagaagtc agcgcaggcc cctgtgttga
      241 tcattaatta tgatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggagcac cgccaccctg accgtcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggatagt aggagtgatc actacatctt cggtactggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01001581             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:17809:3097
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001581
VERSION     KCVO01001581.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:17809:3097"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..426
                     /note="immunoglobulin light chain variable region"
     V_region        100..426
     V_segment       100..392
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73610.1"
                     /translation="DYYCFVYYSGTQFF"
     J_segment       397..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>465
                     /gene="IGLC"
BASE COUNT           99 a          154 c          114 g           98 t
ORIGIN      
        1 acatgggggg agccagagat cccttccaat accagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtggctc cagcactgga
      181 gcagtcacca gtggtaactt tccaaactgg ttccagcaga aacctggaca agtccccagg
      241 ggactgattt acaatacaaa caacaaacac tcctggaccc ctgcccggtt ctcaggctcc
      301 ctcgctgggg gcaaagctgc cctgacactg tcaggagcac agcccgagga cgaggctgat
      361 tattactgct tcgtgtacta tagtggtact caattcttcg gaggagggac ccggctgacc
      421 gtcctacgtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001582             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:24856:13812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001582
VERSION     KCVO01001582.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:24856:13812"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..306
                     /note="immunoglobulin light chain variable region"
     V_region        87..306
     V_segment       87..266
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <228..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73611.1"
                     /translation="DYYCYSTENTDTHRGFF"
     J_segment       270..306
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           66 a          107 c           96 g           75 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacaga agccaggcca gtcccctgtg ctgatcatct
      121 atgaggacag caaacggccc tctgggatcc ctgagagatt ctctggctcc agttcaggga
      181 cagtggccac cttgactatc ggtggggccc aggtggagga tgaagctgac tactactgtt
      241 actcaacaga gaacactgat actcataggg gcttcttcgg aggagggacc cggctgaccg
      301 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001583             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:25929:20174
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001583
VERSION     KCVO01001583.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:25929:20174"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73612.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          160 c          125 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgt cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001584             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:22217:7280
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001584
VERSION     KCVO01001584.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:22217:7280"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73613.1"
                     /translation="DYYCYSTDSSGNHIF"
     J_segment       389..423
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           94 a          145 c          120 g          102 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccaaaaaa gtatgcttat tggttccagc agaagccagg ccagtcccct gtgctgatca
      241 tctatgacga cagtaaacgg ccctctggga tccctgagag attctctggc tccagctcag
      301 ggacagtggc caccttgact atcagtgggg cccaggtgga ggatgaagct gactactact
      361 gttactcaac agatagcagt ggtaatcaca tcttcgctac tgggacccgg ctcaccgtcc
      421 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCVO01001585             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:10314:4048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001585
VERSION     KCVO01001585.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10314:4048"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73614.1"
                     /translation="DYYCSSTDSSGSYVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           91 a          143 c          126 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tactgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gacagtagtg gtagttatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001586             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:11880:8853
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001586
VERSION     KCVO01001586.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11880:8853"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..432
                     /note="immunoglobulin light chain variable region"
     V_region        106..432
     V_segment       106..401
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73615.1"
                     /translation="DYFCSSYTGSITLF"
     J_segment       402..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>471
                     /gene="IGLC"
BASE COUNT           86 a          157 c          118 g          110 t
ORIGIN      
        1 acatggggct ggggtctcag gaggcagcgc tctcaggacg tctccaccat ggtctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagcctccct ctgtgtctgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgaca tcggtggtta taactatgtc tcctggtacc aacggcaccc aggcaaagcc
      241 cccaaattca tgatttatga tgtcaataag cggccctcag gggtctctga tcgcttctct
      301 ggctccaaat ctggcaacac ggcctccctg accatctctg ggctccagtc tgaggatgag
      361 gctgattatt tctgcagctc atatacaggc agcatcactt tattcggagg agggacccgg
      421 ctgaccgtcc tacgtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001587             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:9848:7655
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001587
VERSION     KCVO01001587.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:9848:7655"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..405
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73616.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           89 a          156 c          128 g          108 t
ORIGIN      
        1 acatggggtg cttcagctgt gggcacagga ggcagcactc aggacagtct ccagcatggc
       61 ctggtctcct ctcctcctca cccttctcat tcactgcaca gggtcctggg cccagtctgt
      121 gctgacgcag ccgccctcag tgtctggggc gcccgggcag agggtcacca tctcctgcac
      181 tgggagcagc tccaacattg gaggttatta tgtgcagtgg taccagcagc ttccaggaac
      241 ggcccccaaa ctcctcatgt atgaaaataa taagcgaccc tcaggggttt ctgatcgatt
      301 ctctggctcc cagtctggta cctcagcctc cctgaccatc actggactcc agtctgagga
      361 tgaggctgat tattactgcc agtcctatga cagcagcctg agtgccgtgt tattcggagc
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01001588             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:22321:8638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001588
VERSION     KCVO01001588.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:22321:8638"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73617.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       391..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          143 c          127 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcagacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccagggggag gatgaagctg actactactg
      361 ttattcaatg gatagcagtg gtactcagag catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001589             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:7857:3437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001589
VERSION     KCVO01001589.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:7857:3437"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73618.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           96 a          145 c          121 g           98 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gacatgcatt
      181 gccagaaaaa tatgcttatt ggtaccagca gaaaccaggc cagtccccta tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgaaaga ttctctggct ccagctcagg
      301 gactgtggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacaacagtg gtcagggctc attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001590             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:14647:16765
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001590
VERSION     KCVO01001590.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:14647:16765"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73619.1"
                     /translation="DYYCQSGDSSANHYIF"
     J_segment       389..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          103 a          135 c          123 g          102 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagagatact
      181 ggcaaaaaaa tatgctcggt ggttccagca gaagccaggc caggcccctg tgttggtgat
      241 atataaagac actgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaatagtt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcagga gacagcagtg ctaatcatta catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001591             478 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:18271:18934
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001591
VERSION     KCVO01001591.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 478)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:18271:18934"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..440
                     /note="immunoglobulin light chain variable region"
     V_region        107..440
     V_segment       107..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>412
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73620.1"
                     /translation="DYYCSSYAGGNSFVLF"
     J_segment       410..440
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>478
                     /gene="IGLC"
BASE COUNT           83 a          158 c          126 g          111 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tggactcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggttctt atatctatgt ctcctggtat caacagcatc caggcacagc
      241 ccccaaactc ttgatttttg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catatgcagg cggcaacagt ttcgtattgt tcggaggagg
      421 gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001592             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:21466:13627
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001592
VERSION     KCVO01001592.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21466:13627"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73621.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       392..424
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT          100 a          137 c          123 g          102 t
ORIGIN      
        1 acatgggggg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactccccc tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agatacattg
      181 ccaaaaaaat atgtatattg gttccagcag aagccaggcc agtcccctgt gttgatcatc
      241 tatgaggaca acaaacggcc ctctgggatt cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cagtggggcc caggtggagg atgaaggtga ctactactgt
      361 tactcaagag atagtagtga aaatcaaagc gtcttcggtg ctgggacccg gctcagcgtc
      421 ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01001593             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:20389:17027
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001593
VERSION     KCVO01001593.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20389:17027"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73622.1"
                     /translation="DYYCQVWDSITDHSIF"
     J_segment       394..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          149 c          133 g           98 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg cttactgcac agtctctgcg gtctcctatg agctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggggacaa
      181 cattggaact gaatatgtgc actggtacca gcagaagcca ccgcaggccc ctgtggtggt
      241 catctattat aatactgacc ggccctcagg gatccctgag cgattctcag gctccaaatc
      301 agggaacacc ggcaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta ttactgatca ttccatcttc ggtgctggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCVO01001594             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:2723:8542
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001594
VERSION     KCVO01001594.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:2723:8542"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..430
                     /note="immunoglobulin light chain variable region"
     V_region        107..430
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73623.1"
                     /translation="DYFCCSYADTYTFVF"
     J_segment       407..430
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>475
                     /gene="IGLC"
BASE COUNT           84 a          156 c          122 g          113 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcatgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactttgt ctcctggtac caacaacatc caggcacagc
      241 ccccaaactc atgatttatg aggtcaatca gcggccctca ggggtctctg atcgcttctc
      301 tggctcaaag tctggcaaca cggcctccct gaccgtctcc ggggtccagg ctgaggacga
      361 ggctgattat ttctgctgct catatgcaga cacctacact tttgttttcg gaagtggcac
      421 caggttgacc gtcgtcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001595             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:12326:19274
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001595
VERSION     KCVO01001595.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:12326:19274"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73624.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       378..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           88 a          141 c          117 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatttg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ttcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gcagtggtaa tcatgttttc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001596             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:8153:5357
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001596
VERSION     KCVO01001596.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8153:5357"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..410
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73625.1"
                     /translation="DYYCGSYRRGTTWIF"
     J_segment       411..446
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           84 a          159 c          130 g          111 t
ORIGIN      
        1 acatggggag gtccagtgct gggatctcag gaggcagcgc tctcgggacg tctccaccat
       61 ggcttgggct ctggtcctcc tcaccctcct cactcagggc acaggatcct gggctcagtc
      121 tgccctgact cagcctccct cagtgtccaa gtctcttgga cagtccgtca ccatctcctg
      181 cactggaacc agcagtgaca ttggtgatta taacgctgtc tcctggtacc agcagtactc
      241 aggcacagcc cccagactcc tgatttatga ggtcactcag cggccctcag gggtctctga
      301 tcgcttctct ggctccaagt ctggctacac ggcctccctg accatttctg ggctccaggc
      361 tgaggatgag gctgattatt actgcggctc atataggagg ggaaccactt ggatattcgg
      421 cggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCVO01001597             320 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:17159:13021
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001597
VERSION     KCVO01001597.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 320)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17159:13021"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..282
                     /note="immunoglobulin light chain variable region"
     V_region        8..282
     V_segment       8..245
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <207..>254
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73626.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       250..282
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        283..>320
                     /gene="IGLC"
BASE COUNT           70 a           86 c          100 g           64 t
ORIGIN      
        1 acatgggggc caggatcacc tgtgggggag acaatgttgg aagtgaaaat gtgcactggt
       61 accaacagaa accagcgcag gcccctgtgg tggtcatcca ttataatagt gaccggccct
      121 cagggatccc tgagcgattc tctggctcca aatcagggaa caccgccacc ctgaccatca
      181 gcggggtcga ggccggggat gaggctgact attactgtca ggtgtgggac agtagtagtg
      241 atcattgtgt attgggagga gggacccggc tgaccgtcct aggtcagccc aaggctgccc
      301 cctcggtcac tctcttcccg
//
LOCUS       KCVO01001598             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:12966:13692
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001598
VERSION     KCVO01001598.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12966:13692"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..404
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73627.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       406..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           90 a          156 c          127 g          107 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacattgg aggttattat gtgcagtggt accagcagct tccaggaacg
      241 gcccccaaac tcctcatata tgaaaataat aagcgaccct caggggtttc tgatcgattc
      301 tctggctccc agtctggtac ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgcca gtcctatgac agcagcctga gtgccgtgtt attcggagca
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001599             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:15672:14993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001599
VERSION     KCVO01001599.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:15672:14993"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    92..306
                     /note="immunoglobulin light chain variable region"
     V_region        92..306
     V_segment       92..270
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <234..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73628.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       271..306
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           61 a          118 c           90 g           75 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacagcaccc aggcaaagcc cccaaactca
      121 tgatttgtga cgtcagtaat cggccctcag gggtctctgc tcgcttctct ggttccaagt
      181 ctggcaatac ggcctccctg atcatctctg ggctccaggc tgaggacgag gctgattatt
      241 actgcagctc atacgcaagc agtagcactt gggttttcgg cggagggacc cgcctgaccg
      301 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001600             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:27830:7130
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001600
VERSION     KCVO01001600.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:27830:7130"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..430
                     /note="immunoglobulin light chain variable region"
     V_region        107..430
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73629.1"
                     /translation="DYFCCSYADTYTFVF"
     J_segment       407..430
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>475
                     /gene="IGLC"
BASE COUNT           83 a          157 c          123 g          112 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactttgt ctcctggtac caacaacatc caggcacagc
      241 ccccaaactc atgatttatg aggtcaatca gcggcccgca ggggtctctg atcgcttctc
      301 tggctcaaag tctggcaaca cggcctccct gaccgtctcc ggggtccagg ctgaggacga
      361 ggctgattat ttctgctgct catatgcaga cacctacact tttgttttcg gaagtggcac
      421 caggttgacc gtcgtcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001601             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:5180:10416
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001601
VERSION     KCVO01001601.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:5180:10416"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73630.1"
                     /translation="DYYCSSYTDSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          155 c          122 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcaataatcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgat catctctggg ttccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacagacag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001602             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:23355:13360
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001602
VERSION     KCVO01001602.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:23355:13360"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73631.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       392..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           91 a          142 c          128 g          103 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccaaaaaa gtatgtttat tggttccagc agaagccagg ccagtcccct gtgctgatca
      241 tctatgagga cagcagacgg ccctctggga tccctgagag attctctggc tccagctcag
      301 ggacagtggc caccttgact atcagtgggg cccaggggga ggatgaagct gactactact
      361 gttattcaat ggatagcagt ggtactcaga gcatcttcgg tgctgggacc cggctcaccg
      421 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCVO01001603             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:16124:13628
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001603
VERSION     KCVO01001603.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:16124:13628"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..402
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73632.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       403..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           82 a          152 c          129 g          113 t
ORIGIN      
        1 acatgggggg ctgggatctc aggaggcagc actctcagga cgtctccacc atggcctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccctga
      121 ctcagtctcc ctctgtgtct gggtctcctg gacagtcggt caccatttcc tgcactggaa
      181 ccagcagtga cattggtggt tttgagcgtg tctcctggta ccaacagcac ccaggcaaag
      241 cccccaaact cttgatttat gaggtcagtt atcggccctc aggggtctct gatcgcatct
      301 ctggttccaa gtctggcaac acggcctccc tgatcatctc tgggctccag gctgaggacg
      361 aggctgatta ttattgcagc tcatacgcaa gtagtagtac ttgggtgttc ggcggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001604             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:12761:13402
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001604
VERSION     KCVO01001604.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12761:13402"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73633.1"
                     /translation="DYYCYSSDSTADYWVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           90 a          141 c          126 g          106 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgattat
      241 ttatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggtt ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtgcag gatgaagctg actactactg
      361 ttactcatca gatagcactg ctgattattg ggtgttcggc ggagggaccc ggctgaccgt
      421 cccaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001605             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:20450:14968
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001605
VERSION     KCVO01001605.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20450:14968"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..424
                     /note="immunoglobulin light chain variable region"
     V_region        105..424
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73634.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       389..424
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>464
                     /gene="IGLC"
BASE COUNT           86 a          141 c          140 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcattggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttctattgg
      241 tcatctatgc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttattcgg aggagggacc cggctgaccg
      421 tcctgggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001606             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:19816:9182
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001606
VERSION     KCVO01001606.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19816:9182"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73635.1"
                     /translation="DYYCYSTDSSGDHRVF"
     J_segment       390..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           94 a          141 c          126 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tcctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagaggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttattcaaca gatagtagtg gtgatcatag ggttttcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001607             456 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:15074:10063
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001607
VERSION     KCVO01001607.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 456)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 456)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:15074:10063"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..380
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73636.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       384..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>456
                     /gene="IGLC"
BASE COUNT           96 a          144 c          121 g           95 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcgttgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 cagaaaaata tgcttattgg taccagcaga aaccaggcca gtcccctatg ctgatcatct
      241 gtgaggacag caaacggccc tctgggatcc ctgaaagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc actggggccc aggtggagga tgaagctgac tactactgtt
      361 actcagcaga caacagtggt cagggctcat tcggaggagg gacccggctg accgtcctag
      421 gtcagcccaa ggcccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001608             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:17139:2559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001608
VERSION     KCVO01001608.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:17139:2559"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73637.1"
                     /translation="DYYCMIWHNNAYVF"
     J_segment       403..438
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           96 a          149 c          114 g          117 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgagcagt ggcatcagtg
      181 ttggtagtta caggatattc tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgaactacca cacagactca gataagcacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga ttttactcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt atgatttggc acaacaatgc ttatgtgttc ggaagtggca
      421 ccaagttgac cgtcctcggt cagcctaagg cttccccctt ggtcactctg ttcccg
//
LOCUS       KCVO01001609             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:6585:22855
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001609
VERSION     KCVO01001609.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:6585:22855"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73638.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       393..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           90 a          138 c          126 g          107 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagt
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccagaaaa atatgcttat tggttccagc agaagccagg ccagtcccct gtgttgatca
      241 ttaatgagga cagcaaacgg ccctctggga tccctgggag attctctggc tccagctcag
      301 ggacagtggc caccttgact ctcagtggtg cccaggtgga ggatgaagct gactactatt
      361 gttcctcaac agatagtagt ggtaattatg ttttcggcgg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001610             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:11369:6351
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001610
VERSION     KCVO01001610.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11369:6351"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73639.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          139 c          143 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgcg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gtattggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttgtgctgg
      241 tcatgtatgg tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001611             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:20740:10706
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001611
VERSION     KCVO01001611.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:20740:10706"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..434
                     /note="immunoglobulin light chain variable region"
     V_region        106..434
     V_segment       106..400
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73640.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       401..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>474
                     /gene="IGLC"
BASE COUNT           86 a          155 c          124 g          109 t
ORIGIN      
        1 acatgggggt gggatctcag gaggcagcac tctcaggacg tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagtctccct ctgtgtctgg gtctcctgga cagtcggtca ccatttcctg cactggaacc
      181 agcagtgaca ttggtgatta taaccgtgtc tcctggtacc aacagcaccc aggcaaagcc
      241 cccaaactca tgatttatga ggtcagtgat cggccctcag gggtctctga tcgcttctct
      301 ggttccaagt ctggcaacac ggcctccctg atcatctctg ggctccaggc tgaggacgag
      361 gctgattatt actgcagctc atacacaagc agtagcactt gggtattcgg cggagggacc
      421 cggctgaccg tccttggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001612             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:19348:13666
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001612
VERSION     KCVO01001612.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:19348:13666"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73641.1"
                     /translation="DYYCSSTDTSGNHVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           90 a          142 c          117 g           97 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aaggtgacta ctactgttcc tcaacagata
      361 ccagtggtaa tcatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001613             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:18454:3013
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001613
VERSION     KCVO01001613.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:18454:3013"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73642.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       393..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          142 c          123 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaagac gacaaacggc cctcttggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaata gatagtagtg gtagtcatag cgtcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001614             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:23260:22909
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001614
VERSION     KCVO01001614.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:23260:22909"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73643.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          160 c          118 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctgag ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001615             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:16761:10125
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001615
VERSION     KCVO01001615.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:16761:10125"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73644.1"
                     /translation="DYYCQVWDITTDHDVF"
     J_segment       391..427
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           94 a          139 c          129 g          103 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatgac ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggttctgcgg cctcctatga gctgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta aaaatgtgca ctggcaccag cagaagccac cgcaggcccc tgttttggtc
      241 atctattatg atatcgaacg gccctcaggg atccctgagc gattctctgg cgccaaatca
      301 gggaacaccg ccaccctgat catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacattac tactgatcat gatgtattcg gaagtggcac caagttgacc
      421 gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001616             297 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:21027:7492
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001616
VERSION     KCVO01001616.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 297)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21027:7492"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..259
                     /note="immunoglobulin light chain variable region"
     V_region        8..259
     V_segment       8..222
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>231
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73645.1"
                     /translation="DYYCQVYDSNTWVF"
     J_segment       223..259
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        260..>297
                     /gene="IGLC"
BASE COUNT           65 a           89 c           76 g           67 t
ORIGIN      
        1 acatggggta aaaacatgtt ctggtaccag cagaagccag gaagcgctcc caggtttttc
       61 ctgcactact actccgactc agacaaccat ctgggacctg gggtccccaa tcgagtctct
      121 ggctccaagg agacctcaag taacacagcg tttttgctca tctctgggct ccagcctgag
      181 gacgaggccg attattactg tcaggtatat gacagtaata cttgggtatt cggcggaggg
      241 acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001617             326 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:11705:7341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001617
VERSION     KCVO01001617.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 326)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 326)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11705:7341"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..288
                     /note="immunoglobulin light chain variable region"
     V_region        8..288
     V_segment       8..252
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>260
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73646.1"
                     /translation="DYYCSSFASSSTWVF"
     J_segment       253..288
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        289..>326
                     /gene="IGLC"
BASE COUNT           65 a          101 c           85 g           75 t
ORIGIN      
        1 acatgggggt caccatttcc tgcactggaa ccagcagtga cattggtggt tataaccgtg
       61 tctcctggta ccaacagcac ccaggcaaag cccccaaact catgatttat gaggtcagta
      121 atcggccctc aggggtctct gatcgcttct ctggctccaa gtctggcaac acggcctccc
      181 tgatcatctc tgggttccag gctgaggacg aggctgatta ttactgcagc tcattcgcaa
      241 gcagtagcac ttgggtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      301 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001618             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:8500:3749
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001618
VERSION     KCVO01001618.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8500:3749"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73647.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       408..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           95 a          160 c          120 g          107 t
ORIGIN      
        1 acatggggca gcttcagctg tgggtacaga aggcaggact caggacaatc tccagcatgg
       61 cctggttccc tctcctcctc accctcctca ctcactgtgc agggtcctgg gcccagtctg
      121 tgctgactca gcctccctca gcgtctgagg ccgccaggaa gagtgtcacc atctcctgtt
      181 ctggaagcac ctccaacatc ggaactaata gtgtatcctg gtaccagcag ctcccagaaa
      241 cggctcccaa actcctcatc tattataatg atcgacgagc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggc acgtcagcct ccctggccat cagtgggctc cagaccgagg
      361 atgaggctga ttattactgc gcagcatggg ataacagcct gagcggttac atcttcggtg
      421 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCVO01001619             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:23548:9807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001619
VERSION     KCVO01001619.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23548:9807"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..372
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73648.1"
                     /translation="DYHCYSPDNSGNRAF"
     J_segment       377..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           95 a          142 c          114 g           95 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggta ccagcagaaa ccaggccagt cccctatact gatcatctat gaggacagca
      241 aacggtcctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ccactgttat tcaccagaca
      361 acagtggcaa tcgggcattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001620             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:12898:18704
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001620
VERSION     KCVO01001620.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12898:18704"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73649.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          155 c          123 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtaatcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgat catctctggg ttccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001621             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:12547:9119
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001621
VERSION     KCVO01001621.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12547:9119"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73650.1"
                     /translation="DYYCQVWDSSNKYVFF"
     J_segment       399..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           91 a          144 c          133 g           99 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca caggctctgt ggcctcctat gagctgactc
      121 agccaccctc ggtgtcggag tccccaggac agacagccag gatcacctgt gggggagaca
      181 tacttggagg tcaaagtgta cactggtacc aacagaagcc accgcaggcc cctgtgttgg
      241 tcttgtatgc tgataacgaa cggccctcag ggatccctga ccgattctct gcctccaatt
      301 cagggaatac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt ctgggacagt agtaataaat atgtattttt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001622             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:8645:10129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001622
VERSION     KCVO01001622.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8645:10129"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..442
                     /note="immunoglobulin light chain variable region"
     V_region        109..442
     V_segment       109..402
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73651.1"
                     /translation="DYYCSLWDSRLSSRVF"
     J_segment       407..442
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>457
                     /gene="IGLC"
BASE COUNT           90 a          142 c          123 g          102 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcagcatc tggggccccc gggcagaggg tcaccatctc ctgcactggg
      181 accagctcca acatcggggc gaattattat gtttcctggt accagcagtt cccaggaaca
      241 gcccccaaac tcctcatcta tgaaaataat aagcgaccct ctggggtttc tgaccgattc
      301 tctggctcca agtctggtac ctcagcctcc ctgaccatct ctggactcca atctgaggat
      361 gaggctgatt attactgctc cctatgggat agcagactga gtagtcgggt attcggcgga
      421 gggacccgac tgaccgtcct aggtcagccc aaggctg
//
LOCUS       KCVO01001623             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:20894:12733
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001623
VERSION     KCVO01001623.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:20894:12733"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..432
                     /note="immunoglobulin light chain variable region"
     V_region        105..432
     V_segment       105..392
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73652.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       396..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           94 a          143 c          127 g          106 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccctcctc actttctgca caggctctgc agcctcctat gagctgacac
      121 agactccctc ggtgtcagtg tccccaggac agacggccag gatctcctgc tctggagatg
      181 cattgccaaa aaaatttgct tcttggttcc agcagaaggc aggccagtcc cctgtgctga
      241 tcatctatga ggacagcaaa cggccctctg ggatccctga gagattctct ggctccagtt
      301 cagggacaat ggccaccttg actatcagtg gggcccaggt ggaggatgaa gctgactact
      361 actgttactc aacagataac agtgatactc ataggggctt cttcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001624             498 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:25731:9030
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001624
VERSION     KCVO01001624.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 498)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:25731:9030"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    139..460
                     /note="immunoglobulin light chain variable region"
     V_region        139..460
     V_segment       139..420
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <388..>432
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73653.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       424..460
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        461..>498
                     /gene="IGLC"
BASE COUNT          108 a          151 c          137 g          102 t
ORIGIN      
        1 acatgggggg aaggaataag agaagcctag ggagcccagc tgtgctgtgg gctcaggagg
       61 cagagctctg ggtgtctcac catggcctgg attcctctcc tactccccat cctcactttc
      121 tgcacaggct ctgcagcctc ctatgagctg acacagccac cctcgttgtc agtgtcccca
      181 ggacagacgg ccaggatcac ctgctctgga gatgcattgc cagaaaaata tgcttattgg
      241 taccagcaga aaccaggcca gtcccctatg ctgatcatct gtgaggacag caaacggccc
      301 tctgggatcc ctgaaagatt ctctggctcc agctcaggga cagtggccac cttgactatc
      361 actggggccc aggtggagga tgaagctgac tactactgtt actcagcaga caacagtggt
      421 cagggctcat tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc
      481 tcggtcactc tcttcccg
//
LOCUS       KCVO01001625             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:17927:12064
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001625
VERSION     KCVO01001625.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:17927:12064"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73654.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          161 c          124 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctac cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001626             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:15563:10735
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001626
VERSION     KCVO01001626.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:15563:10735"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..442
                     /note="immunoglobulin light chain variable region"
     V_region        109..442
     V_segment       109..402
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73655.1"
                     /translation="DYYCSLWDSRLSSRIF"
     J_segment       410..442
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           93 a          155 c          125 g          107 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcagcatc tggggccccc gggcagaggg tcaccatctc ctgcactggg
      181 accagctcca acatcggggc caattattat gtttcctggt accagcagtt cccaggaaca
      241 gcccccaaac tcctcatcta tgaaaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggtac ctcagcctcc ctgaccatct ctggactcca atctgaggat
      361 gaggctgatt attactgctc actatgggat agcaggctga gtagtcggat attcggcgga
      421 gggacccgac tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001627             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:7976:10129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001627
VERSION     KCVO01001627.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:7976:10129"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..441
                     /note="immunoglobulin light chain variable region"
     V_region        111..441
     V_segment       111..403
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <366..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73656.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       405..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           89 a          155 c          127 g          108 t
ORIGIN      
        1 acatggggct tcagctgtgg gcacaggagg cagcactcag gacagtctcc agcatggcct
       61 ggtctcctct cctcctcacc cttctcattc actgcacagg gtcctgggcc cagtctgtgc
      121 tgacgcagcc gccctcagtg tctggggcgc ccgggcagag ggtcaccatc tcctgcactg
      181 ggagcagttc caacattgga ggttattatg tgcagtggta ccagcagctt ccaggaacgg
      241 cccccaaact cctcatgtat gaaaataata agcgaccctc aggggtttct gatcgattct
      301 ctggctccca gtctggtacc tcagcctccc tgaccatcac tggactccag tctgaggatg
      361 aggctgatta ttactgccag tcctatgaca gcagcctgag tgccgtgtta ttcggagcag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001628             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:8090:8804
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001628
VERSION     KCVO01001628.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8090:8804"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73657.1"
                     /translation="DYYCSSTDSRDNHRVF"
     J_segment       388..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           94 a          142 c          127 g           98 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 cagaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgtg ctgatcgtct
      241 atgaggacaa caaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac gttgactatc agtggggccc aggtggagga tgaagctgac tactactgtt
      361 cctcaacaga tagcagggat aatcataggg tattcggcgg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001629             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:17369:16574
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001629
VERSION     KCVO01001629.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:17369:16574"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73658.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          155 c          124 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtaa tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catatgcaag cagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001630             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:16830:8573
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001630
VERSION     KCVO01001630.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:16830:8573"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..432
                     /note="immunoglobulin light chain variable region"
     V_region        108..432
     V_segment       108..398
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <366..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73659.1"
                     /translation="DYYCCSYAGRYLF"
     J_segment       399..432
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           82 a          157 c          127 g          104 t
ORIGIN      
        1 acatgggggg ctggggtctc agacggcagc gctctcggga catctccacc atggcctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccctga
      121 ctcagcctcg ctcagtgtct gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga catcggtggt tctaactatg tctcctggta ccaacagtat ccaggcacag
      241 cccccaaact catgatttat gaggtcagta agcggccctc aggggtctcg agtcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag gctgaggacg
      361 aggctgatta ttactgctgc tcatatgcag gcaggtactt attcggagga gggacccggc
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001631             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:4830:19921
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001631
VERSION     KCVO01001631.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:4830:19921"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73660.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           85 a          155 c          124 g          109 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacactagca gtagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001632             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:5581:6266
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001632
VERSION     KCVO01001632.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:5581:6266"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..441
                     /note="immunoglobulin light chain variable region"
     V_region        93..441
     V_segment       93..401
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73661.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       404..441
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           95 a          156 c          118 g          110 t
ORIGIN      
        1 acatggggac tgtggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct ccaagcctat gctgactcag ccggcctccc
      121 tctcagcatc tcctggagca tcagccagtc tcacatgcac cttcagcggt ggcatcaatg
      181 ttgctggcta ccacatacac tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgagatacaa atcagactca gataatggcc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tggttcagcg aacacaggga ttttacgcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gccattggac acagcagcgg tgattacatc ttcggtgctg
      421 ggacccggct caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001633             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:12742:18984
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001633
VERSION     KCVO01001633.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:12742:18984"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..388
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73662.1"
                     /translation="DYYCQVWDSSSKCVLF"
     J_segment       394..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           95 a          144 c          132 g           94 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatggc ctggaccctt
       61 ctcctcctcg gcctcctcgc tcactgcaca ggctctgcgg cctcctatga tctgactcag
      121 ccaccctcgg tgtcagcggc ctcaggacag acggccagga tcacctgtgg gggagacaac
      181 attggaagta aaaatttaca ctggtaccag cagaagccag cgcaggcccc tgtgttggtc
      241 atctgtgctg ataataaacg gccctcaggg atccctgagc gaatctctgg ctccaactca
      301 ggaaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggttt gggacagtag tagtaaatgc gttttattcg gaggagggac ccgactgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001634             312 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:10973:16511
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001634
VERSION     KCVO01001634.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 312)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 312)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:10973:16511"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    33..274
                     /note="immunoglobulin light chain variable region"
     V_region        33..274
     V_segment       33..240
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <202..>246
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73663.1"
                     /translation="DFYCSSTDSSGNHVF"
     J_segment       244..274
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        275..>312
                     /gene="IGLC"
BASE COUNT           64 a           91 c           88 g           69 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca cggccagaaa aatatgctta ttggttccag
       61 cagaagccag gccagtcccc tgtgttgatc atcaatgagg acagcaaacg gccctctggg
      121 atccctgaga gattctctgg ctccagctcc gggacagtgg ccaccttgac tctcagtggg
      181 gcccaggtgg aggatgaagc tgacttctac tgttcctcaa cagatagtag tggtaatcat
      241 gtcttcggcg gagggacccg gttgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      301 actctcttcc cg
//
LOCUS       KCVO01001635             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:18501:2571
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001635
VERSION     KCVO01001635.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18501:2571"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..368
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73664.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           93 a          142 c          114 g           97 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gacaaatatg
      181 cttattggta ccggcagaaa ccaggccagt cccctatact gatcatctat gaggacagca
      241 aacggccctc tgggatccct gaaagattct ctggctccag ttcagggaca gtggccacct
      301 tgactatcac tggggcccag gtggaggatg aagctgacta ctactgttac tctgcagaca
      361 acagtggtca gggctcattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001636             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1101:23919:16936
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001636
VERSION     KCVO01001636.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:23919:16936"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73665.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           88 a          155 c          123 g          107 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acaacaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca gtagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001637             324 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:22435:13547
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001637
VERSION     KCVO01001637.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 324)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 324)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..324
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:22435:13547"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..286
                     /note="immunoglobulin light chain variable region"
     V_region        8..286
     V_segment       8..246
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <208..>258
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73666.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       250..286
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        287..>324
                     /gene="IGLC"
BASE COUNT           68 a           93 c           89 g           74 t
ORIGIN      
        1 acatgggcgg ccaggatctc ctgctctgga gatgcattgc caaaaaaatt tgcttcttgg
       61 ttccagcaga agccaggcca gtcccctgtg ctgatcatct atgacgacag caaacggccc
      121 tctgggatcc ctgagagatt ctctggctcc agctcaggga cagtggccac cttgactatc
      181 attggggccc aggtggagga tgaagctgac taccactgtt tctcaacaga tagcagtggt
      241 aatcataggg gcttattcgg aggcgggacc cggctgattg tcctaggtca gcccaaggct
      301 gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001638             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:18131:18633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001638
VERSION     KCVO01001638.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18131:18633"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..447
                     /note="immunoglobulin light chain variable region"
     V_region        99..447
     V_segment       99..410
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73667.1"
                     /translation="DYYCQIYDSSANTLF"
     J_segment       413..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           97 a          165 c          115 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtactg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagagacc
      181 tcagtgttgg caataaaaac atgtactggt accagcagaa gccagggagc gctcccagat
      241 ttttcctata ctactcctcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaactaaca cagcgttttt gctcatctct ggactccagc
      361 ctgaggacga ggccgattat tactgtcaga tatatgacag tagtgctaat acgttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001639             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:13452:8545
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001639
VERSION     KCVO01001639.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:13452:8545"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..400
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73668.1"
                     /translation="DYYCCSYTTSSTFIF"
     J_segment       401..434
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           88 a          153 c          116 g          115 t
ORIGIN      
        1 acatgggggg ggtctcagaa ggcagcgctc tcaggacgtc tccaccatgg cttggactct
       61 gctcctcgtc accctcctca ctcaaggcac aggatcctgg gctcagtctg ccccgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgatatt gggtattata atactgtgtc ttggtaccaa cagcacccag gcacagcccc
      241 caaagtcatg atttatggtg tcagtaatcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgttgttcat atacaaccag tagcactttc atcttcggtg atgggacccg
      421 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01001640             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:20784:12040
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001640
VERSION     KCVO01001640.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20784:12040"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..390
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73669.1"
                     /translation="DYYCYSMDSSTYLGFF"
     J_segment       392..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           92 a          146 c          125 g          104 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccctcctc actttctgca caggctctgc agcctcctat gagctgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg
      181 cattgccaaa aaaatacgct tattggttcc agcagaagcc aggccagtcc cctgtgctga
      241 tcatctatga ggacaccaaa cggccctctg ggatccctga gagattctct ggctccagct
      301 cagggacagt ggccaccttg actatcagtg gggcccaggt ggaggatgaa gctgactact
      361 actgttactc aatggatagc agtacttatc ttggcttctt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001641             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:8418:10820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001641
VERSION     KCVO01001641.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8418:10820"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..433
                     /note="immunoglobulin light chain variable region"
     V_region        109..433
     V_segment       109..396
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73670.1"
                     /translation="DYYCQVWDSGNKYVLF"
     J_segment       397..433
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           92 a          145 c          139 g           95 t
ORIGIN      
        1 acatggggga gcctgacttt gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgctcactgc acagtaggct ctgcggcctc ctatgaactg
      121 actcagccac cctcggtgtc ggtgtcccca ggacagacag ccaggatcac ctgtaggggg
      181 gacaacattg gaagtagaag tgtgcattgg taccaacaga agccaccgca ggcccctgtg
      241 ctggtcattt atggtgatag cgaacggccc tcagggatcc ctgaccgatt ctctgcctcc
      301 aactcaggga acaccgccac cctgaccatc agcggggtcg aggccgggga tgaggctgac
      361 tattactgtc aggtgtggga cagtggtaat aaatacgtgt tattcggagg agggacccgg
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001642             337 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:20723:12851
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001642
VERSION     KCVO01001642.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 337)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 337)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..337
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:20723:12851"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..299
                     /note="immunoglobulin light chain variable region"
     V_region        8..299
     V_segment       8..261
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <224..>271
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73671.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       265..299
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        300..>337
                     /gene="IGLC"
BASE COUNT           72 a           98 c           95 g           72 t
ORIGIN      
        1 acatggggtg tccccaggac agacggccag gatcacctgc tctggagatg cattgccaaa
       61 aaagtatgct tattggttcc agcagaagcc aggccagtcc cctgtgctga tcatctatga
      121 ggacagcaga cggccctctg ggatccctga gagattctct gcctccagct cagggacagt
      181 ggccaccttg actatcagtg gggcccaggg ggaggatgaa gctgactact actgttattc
      241 aatggatagc agtggtactc agagcatctt cggtgctggg acccggctca ccgtcctagg
      301 tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01001643             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:20458:2879
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001643
VERSION     KCVO01001643.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20458:2879"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..400
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73672.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       401..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           82 a          151 c          127 g          114 t
ORIGIN      
        1 acatgggggt gggatctcag gaggcagcac tctcaggacg tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagtctccct ctgtgtctgg gtctcctgga cagtcggtca ccatttcctg cactggaacc
      181 agcagtgaca ttggtggttt tgagcgtgtc tcctggtacc aacagcaccc aggcaaagcc
      241 cccaaactct tgatttatga ggtcagttat cggccctcag gggtctctga tcgcttctct
      301 ggttccaagt ctggcaacac ggcctccctg atcatctctg ggctccaggc tgaggacgag
      361 gctgattatt attgcagctc atacgcaagt agtagtactt gggtattcgg cggagggacc
      421 cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001644             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:8028:14034
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001644
VERSION     KCVO01001644.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8028:14034"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73673.1"
                     /translation="DYYCYSTDSSSNHGLF"
     J_segment       375..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           94 a          140 c          115 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttgttggtt ccagcagaag ccaggccagt cccctgtatt gatcatctat gaggacaaga
      241 aacggccccc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagata
      361 gcagttctaa tcatggctta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001645             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:20520:11854
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001645
VERSION     KCVO01001645.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:20520:11854"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73674.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       410..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          156 c          129 g          109 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gaccccgggc agagggtcac catctcgtgc
      181 actgggagca gctccaacat tggaggttat tttgtatact ggtaccagca gttcccagga
      241 acagccccca aactcctcat ctatgacaat tataagcgac cctcagggat ttctgaccga
      301 ttctctggct ccaagtctgg tacctcagcc tccctgacca tcactgggct ccagcctggg
      361 gatgaggctg attattactg cggagcatgg gatagcagcc tgagtgctcg cttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01001646             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:8967:19242
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001646
VERSION     KCVO01001646.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:8967:19242"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73675.1"
                     /translation="DYFCQVWDSTNKYVLF"
     J_segment       396..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          149 c          134 g           95 t
ORIGIN      
        1 acatgggggc ctgactttgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactgcac aggctctgcg gcctcctatg agctgactca
      121 gccaccctcg gtgtcggtgt ccccaggaca gacagccagg atcacctgtg ggggagacaa
      181 cattggacgt gaaagtgtgc actggtacca acagaagcca ccgcaggccc ctctgttggt
      241 catatattct ggtggcgaac ggccctcagg gatccctgag cgattctctg cctccatctc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactattt
      361 ctgtcaggtg tgggacagta ctaataaata cgtactattc ggaggaggga cccgactgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001647             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:11289:15754
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001647
VERSION     KCVO01001647.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:11289:15754"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73676.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          161 c          124 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga gaccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001648             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:16420:7362
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001648
VERSION     KCVO01001648.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16420:7362"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73677.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       412..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          156 c          129 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggaccccgg gcagagggtc accatctcgt
      181 gcactgggag cagctccaac attggaggtt attttgtata ttggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctatgaca ataataagcg accctcaggg atttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagcctg
      361 gggatgaggc tgattattac tgcggagcat gggatagcag cctgagtgct cgcttattcg
      421 gaggagggac ccgtctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001649             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:24294:13801
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001649
VERSION     KCVO01001649.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:24294:13801"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73678.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           91 a          156 c          128 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagtaac agtgtgtcct ggtacctgca gctcccagaa
      241 acggctccca aactcctcat ctattctaat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cccgtcagcc tccctggcca tcagtgggct cgagaccgaa
      361 gatgaggctg attattactg cgcagtatgg gatgatagcc tgagcggtgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01001650             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:20622:3450
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001650
VERSION     KCVO01001650.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20622:3450"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..383
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73679.1"
                     /translation="DYYCYSTDSSGNGLF"
     J_segment       384..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           97 a          140 c          122 g           99 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcgttgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 cagaaaaata tgtttattgg taccagcaga aaccaggcca gtcccctgtg ctgatcatct
      241 atgaggacag caaacggccc tctgggatcc ctgaaagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc agtggggccc aggtggagga tgaagctgac tactactgtt
      361 actcaacaga cagcagtggt aatggcttat tcggaggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001651             479 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:12993:10469
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001651
VERSION     KCVO01001651.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 479)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:12993:10469"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    111..441
                     /note="immunoglobulin light chain variable region"
     V_region        111..441
     V_segment       111..404
                     /gene="IGLV8-111"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>413
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73680.1"
                     /translation="DYYCLLSMGSGIVLF"
     J_segment       407..441
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>479
                     /gene="IGLC"
BASE COUNT           88 a          149 c          128 g          114 t
ORIGIN      
        1 acatggggag ctgagaagcc tgagagcact tggccttcat aagtgtcccc accatggcct
       61 ggatgatgct tctcctcgga ctccttgctt atggctcagg agtggattcc gagactgtgg
      121 tgacccagga gccatcgttg tcagtgtccc ctggagggac agtcacactc acctgtggcc
      181 tgagctctgg ctcagtctct accagtaagt accccagctg gtaccagcag accccaggcc
      241 aggctccacg catgcttatc ttcagcacaa acagtcgccc ttctggggtc cctgatcgtt
      301 tctctggctc catccttggg aacaaggctg ccctcaccat cacgggggct caggcagacg
      361 atgaatctga ttattactgt ttgctctcca tgggtagtgg cattgtctta ttcggaggag
      421 ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001652             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:20902:3121
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001652
VERSION     KCVO01001652.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:20902:3121"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73681.1"
                     /translation="DYYCQVWGITSEHPLF"
     J_segment       392..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          145 c          131 g           96 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatgacct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ctctgtggcc tcctatgacc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgcgggg gtgacaaaac
      181 tggaagtaac aatgtacact ggtaccagca gaagccaccg caggcccctg ttctggtcat
      241 ctattttgat agcgagcggc cctcagggat ccctgagcga tactctggct ccaaatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg ggcattacta gtgagcatcc tttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001653             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:6434:17723
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001653
VERSION     KCVO01001653.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6434:17723"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73682.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       392..424
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           93 a          141 c          125 g          103 t
ORIGIN      
        1 acatgggggg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactccccc tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agatgcattg
      181 ccaaaaaagt atgcttattg gttccagcag aagccaggcc agtcccctgt gttgatcatc
      241 tatgaagacg acaaacggcc ctctgggatc cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cagtggggcc caggtggagg atgaaggtga ctactactgt
      361 tactcaatag acagtagtgg tagtcatagc gtcttcggtg ctgggacccg gctcaccgtc
      421 ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01001654             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:10662:11359
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001654
VERSION     KCVO01001654.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10662:11359"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73683.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           92 a          144 c          125 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 tccctcggtg tcagtgtccc caggacagac ggccaggatc tcctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaaggcaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagttcagg
      301 gacaatggcc accttgacta tcagtggggc ccaggtggag gatgacgctg actactactg
      361 ttactcaaca gataacagtg atactcatag gggcttcttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001655             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:5963:12821
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001655
VERSION     KCVO01001655.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5963:12821"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..390
                     /gene="IGLV7-47"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73684.1"
                     /translation="EYYCWLHYSGAVLF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          149 c          116 g          108 t
ORIGIN      
        1 acatgggggg agccagggat cccttccaat accagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcactga ctgtgtcccc aggagggaca gtcactctca cttgtggctc cactattgga
      181 gcagtcactg ggagtcatta tccctactgg ttccagcaga agcctggcca agcccctaaa
      241 acactgattt atgatacaaa caataagctc tcctggaccc ctgcccggtt ctcaggctcc
      301 ctccttgggg ataaagctgc cctgacactg tccggtgcgc agcctgagga tgaagctgaa
      361 tattactgct ggctgcacta tagtggtgct gtgttattcg gaggagggac ccgactgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001656             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:19983:20688
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001656
VERSION     KCVO01001656.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:19983:20688"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73685.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       391..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           94 a          143 c          125 g          103 t
ORIGIN      
        1 acatgggggg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactccccc tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatct cctgctctgg agatgcattg
      181 ccaaaaaaat ttgcttcttg gttccagcag aaggcaggcc agtcccctgt gctgatcatc
      241 tatgaggaca acaaacggcc ctctgggatc cctgagagat tctctggctc cagttcaggg
      301 acagtggcca ccttgactat cagtggggcc caggtggagg atgaagctga ctactactgt
      361 tactcaacag ataacagtga tactcatagg ggcttcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001657             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:22593:17225
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001657
VERSION     KCVO01001657.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:22593:17225"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73686.1"
                     /translation="DYYCYSTDSSGTHIF"
     J_segment       374..408
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           91 a          145 c          110 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gacgacagta
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagata
      361 gcagtggtac tcacatcttc gctcctggga cccggctcac cgtcctaggt cagcccaagg
      421 cttcccccac ggtcactctg ttcccg
//
LOCUS       KCVO01001658             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:10096:3095
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001658
VERSION     KCVO01001658.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10096:3095"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73687.1"
                     /translation="DYYCYSIDSNTYLGFF"
     J_segment       388..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           94 a          145 c          121 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc gcctgctctg gagatgcatt
      181 gccaaaaaaa tacgcttatt ggttccagca gaagccaggc cagtcccctg tactgatcat
      241 ctatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaata gatagcaata cttatcttgg cttcttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001659             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:20388:8659
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001659
VERSION     KCVO01001659.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:20388:8659"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73688.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          161 c          126 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc ggctcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001660             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:7202:12138
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001660
VERSION     KCVO01001660.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7202:12138"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73689.1"
                     /translation="DYYCGAWDSSLSVRLF"
     J_segment       412..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          156 c          130 g          109 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggaccccgg gcagagggtc accatctcgt
      181 gcactgggag cagctccaac attggaggtt attttgtata ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctatgaca ataataagcg accctcaggg atttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagcctg
      361 gggatgaggc tgattattac tgcggagcat gggatagcag cctgagtgtt cgcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001661             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:10644:13367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001661
VERSION     KCVO01001661.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:10644:13367"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73690.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       390..424
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           91 a          143 c          126 g          102 t
ORIGIN      
        1 acatggggtg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactccccc tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agatgcattg
      181 ccaaaaaagt atgcttattg gttccagcag aagccaggcc agtcccctgt gctgatcatc
      241 tatgaggaca gcagacggcc ctctgggatc cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cagtggggcc cagggggagg atgaagctga ctactactgt
      361 tattcaatgg atagcagtgg tactcagagc atcttcggtg ctgggacccg gctcaccgtc
      421 ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01001662             382 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:14485:12341
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001662
VERSION     KCVO01001662.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 382)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14485:12341"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    20..344
                     /note="immunoglobulin light chain variable region"
     V_region        20..344
     V_segment       20..307
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <269..>316
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73691.1"
                     /translation="DYYCQVWDSSSDHCLL"
     J_segment       311..344
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        345..>382
                     /gene="IGLC"
BASE COUNT           77 a          110 c          116 g           79 t
ORIGIN      
        1 acatgggggc tctgcggtct cctatgacct gactcagcca ccctcggtgt cagtgtcccc
       61 aggacagacg gccaggatca cctgtggggg agacaatgtt ggaagtgaat atgtgcactg
      121 gtaccaacag aggccaccgc aggcccctgt ggtggtcatc cattataata gtgaccggcc
      181 ctcagggatc cctgagcgat tctctggctc caaatcaggg aacaccgcca ccctgaccat
      241 cagcggggtc gaggccgggg atgaggctga ctattactgt caggtgtggg acagtagtag
      301 tgatcattgt ttattgggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc
      361 cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001663             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:20294:13814
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001663
VERSION     KCVO01001663.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20294:13814"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73692.1"
                     /translation="DYYCQVWDSSSDHILF"
     J_segment       392..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          144 c          136 g           98 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgag ttgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaacc
      181 ttggagataa atatgtacac tggtaccagc agaagccacc gcgggcccct gtgctggtca
      241 tctactatga tagtgaccgg ccctcatgga tccctgagcg attctctggg tccaaatcag
      301 ggatcaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatcata tcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001664             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:23838:17604
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001664
VERSION     KCVO01001664.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:23838:17604"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73693.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          145 c          124 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctctgagc tgacacagcc
      121 accctcggtg tcagtgtccc ccggacagac ggccaggatc acctgctctg gaaatgcatt
      181 gccaaaatac tatgcttatt ggttccagca gaagccaggc cagtcccctg tggcgatcat
      241 ctatgaggac aacaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtagag gatgaggctg actactactg
      361 ttactcaaca gatagcagtg gtactaatgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001665             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:5441:11419
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001665
VERSION     KCVO01001665.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:5441:11419"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73694.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          139 c          138 g           99 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctccttt gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcattggaat tagaaatgtg cagtggtacc agcagaagcc accgcagggc cttgtactgg
      241 tcatctatac tgatagcgaa cggccctcag ggatccctga gcgattttct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001666             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:18020:19028
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001666
VERSION     KCVO01001666.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18020:19028"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73695.1"
                     /translation="DYYCSSFASSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          155 c          124 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtaatcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgat catctctggg ttccaggctg aggacgaggc
      361 tgattattac tgcagctcat tcgcaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001667             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:15874:18631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001667
VERSION     KCVO01001667.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:15874:18631"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73696.1"
                     /translation="DYYCYSTDSSGNGLF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           95 a          138 c          115 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 tttattggta ccagcagaaa ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gaaagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagaca
      361 gcagtggtaa tggcttattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001668             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:4514:13613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001668
VERSION     KCVO01001668.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:4514:13613"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..454
                     /note="immunoglobulin light chain variable region"
     V_region        130..454
     V_segment       130..417
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73697.1"
                     /translation="DYYCYSTDTSGNHRVF"
     J_segment       419..454
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT          105 a          151 c          133 g          103 t
ORIGIN      
        1 acatggggaa gagaagccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactccccc tcctcacttt ctgcacaggc
      121 tctgcagcct cctatgagct gacacagcca ccctcggtgt cagtgtcccc aggacagacg
      181 gccaggatca cctgctctgg agatgcattg ccaaaaaaat atgcttattg gttccagcag
      241 aagccaggcc agtcccctgt actgatcatc tatgaggaca gcaaacggcc ctctgggatc
      301 cctgagagat tctctggctc cagctcaggg acagtggcca ccttgactat cagtggggcc
      361 caggcggagg atgaagctga ctactactgt tactcaacag ataccagtgg taatcatagg
      421 gtattcggcg gagggacccg actgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      481 actctcttcc cg
//
LOCUS       KCVO01001669             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:17398:6931
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001669
VERSION     KCVO01001669.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:17398:6931"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..431
                     /note="immunoglobulin light chain variable region"
     V_region        103..431
     V_segment       103..397
                     /gene="IGLV2-10"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73698.1"
                     /translation="DYYCSSFEASDTYIF"
     J_segment       398..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>471
                     /gene="IGLC"
BASE COUNT           82 a          157 c          119 g          113 t
ORIGIN      
        1 acatgggggc tggggtctcg gcagcgctct ctggacgtct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca gggtcctggg ctcagtctgc cccgattcag
      121 tctccctctg tgtctgggtc tcttggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgacattg ggcgttataa ctatgtctcc tggtaccgac agcagccagg cacgaccacc
      241 aaactcataa tgtataaagt caatatgcgg ccctcagggg tttctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctggac tccaggctga cgacgagggt
      361 gattattact gtagctcttt tgaggccagc gacacttaca tcttcggtac tgggacccgg
      421 ctcaccgtcc tgggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCVO01001670             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:19341:4679
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001670
VERSION     KCVO01001670.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:19341:4679"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73699.1"
                     /translation="DYYCSSYTDSSTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          156 c          123 g          108 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtggtt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcaataa tcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gatcatctct gggttccagg ctgaggacga
      361 ggctgattat tactgcagct catacacaga cagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001671             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:17053:9287
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001671
VERSION     KCVO01001671.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:17053:9287"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..444
                     /note="immunoglobulin light chain variable region"
     V_region        120..444
     V_segment       120..407
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73700.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       411..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          148 c          144 g           98 t
ORIGIN      
        1 acatggggga gaggaacctg cccagcctgg cctcgggaag cagccttggc ggtgcctcag
       61 ccatggccgg gacccttctc ctcctcggcc tccttgctta ctgcacaggc tctgcggtct
      121 cctatgagct cactcagcca ccctcggtgt cagtgtcccc aggacagacg gccaggatca
      181 cctgtggggg aggcaatgtt ggaagtgaat atgtccactg gtatcaacag aagccaccgc
      241 aggcccctgt ggtggtcatc tattataata ctgaccggcc ctcagggatc cctgagcgat
      301 tctctggctc caaatcaggg aacaccgcca ccctgaccat cagcggggtc gaggccgggg
      361 atgaggctga ctattactgt caggtgtggg acagtaggag tgatcatagt ttattgggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001672             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1101:19077:4053
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001672
VERSION     KCVO01001672.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:19077:4053"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73701.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           89 a          141 c          120 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatctcct gctctggaga tggattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag gcaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagtttct ctggctccag ttcagggaca gtggccacct
      301 tgactatcgg tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagata
      361 acagcgatac tcataggggc ttcttcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001673             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:20977:3736
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001673
VERSION     KCVO01001673.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:20977:3736"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..424
                     /note="immunoglobulin light chain variable region"
     V_region        103..424
     V_segment       103..384
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73702.1"
                     /translation="DYYCQVWDSNSGVLF"
     J_segment       387..424
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           85 a          138 c          142 g           97 t
ORIGIN      
        1 acatgggggc tggcctcggg aagcagcctt ggcggtgcct cagccatggc cgggaccctt
       61 ctcctcctcg gcctccttgc tcactgcaca gattctgtgg tctcctatga attgactcag
      121 ccacgctcag tgtccgtgtc cccaggacag acggccagga tcacctgtgg gggagacagc
      181 gttggaagta gaagtgtgca gtggtaccag cagaagccac cgcaggccct tgtactggtc
      241 atctatgctg atagggaacg gccctcaggg atccctgagc gattctctgg ctccaattta
      301 gggaacaccg ccaccctgac catcagcggc gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtaa tagtggtgtg ttattcggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001674             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:22652:8157
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001674
VERSION     KCVO01001674.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22652:8157"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73703.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       397..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          141 c          139 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagactctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaaacc agcgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gttgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgtgtatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001675             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:9181:14530
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001675
VERSION     KCVO01001675.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:9181:14530"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..392
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73704.1"
                     /translation="DYYCFVYYSGTQFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           99 a          153 c          115 g           98 t
ORIGIN      
        1 acatgggggg agccagagat cccttccaat accagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtggctc cagcactgga
      181 gcagtcacca gtggtaactt tccaaactgg ttccagcaga aacctggaca agtccccagg
      241 ggactgattt acaatacaaa caacaaacac tcctggaccc ctgcccggtt ctcaggctcc
      301 ctcgctgggg gcaaagctgc cctgacactg tcaggagcac agcccgagga cgaggctgat
      361 tattactgct tcgtgtacta tagtggtact caattcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001676             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:8469:4170
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001676
VERSION     KCVO01001676.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8469:4170"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73705.1"
                     /translation="DYYCSSYASSSTWIF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          157 c          122 g          107 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat aatttatgag gtcagtgatc ggccctcagg ggtctctgct cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacgcaagca gtagcacttg gatattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001677             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:16408:7919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001677
VERSION     KCVO01001677.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:16408:7919"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73706.1"
                     /translation="DYYCSSTDSRGNYVF"
     J_segment       392..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           92 a          140 c          127 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggg cagtcccctg tgttgatcat
      241 caatgaggac agcaaacgac cctctgggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagtagag gtaattatgt gttcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001678             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:14681:20312
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001678
VERSION     KCVO01001678.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14681:20312"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73707.1"
                     /translation="DYYCVIWHNNAWVF"
     J_segment       403..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           93 a          152 c          117 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgagcagt gacatcagtg
      181 ttggtagtta caggatattc tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgaattacca cacagactca gataaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tgcttcggcc aatgcaggga tttttctcat ctctgggctc cagtctgagg
      361 atgaggctga ctattactgt gtgatttggc acaacaatgc ttgggttttc ggcggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001679             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:13371:9071
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001679
VERSION     KCVO01001679.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13371:9071"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..427
                     /note="immunoglobulin light chain variable region"
     V_region        103..427
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73708.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       392..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          141 c          139 g           96 t
ORIGIN      
        1 acatgggggc tggcctcggg aagcagcctt ggcggtgcct cagccatggc cgggaccctt
       61 ctcctcctcg gcctccttgc ttactgcaca gggtctgcgg tctcctatga gctcactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagga tcacctgtgg gggaggcaat
      181 gttggaagtg aatatgtcca ctggtatcaa cagaagccac cgcaggcccc tatggtggtc
      241 atctattata atagtgaccg gccctcaggg atccctgagc gattctctgg ctccaaatca
      301 gggaacaccg ccaccctgac catcagcgga gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggacagtag gagtgatcat agcttattgg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001680             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:6442:14249
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001680
VERSION     KCVO01001680.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:6442:14249"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..447
                     /note="immunoglobulin light chain variable region"
     V_region        114..447
     V_segment       114..407
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73709.1"
                     /translation="DYFCSVWDSSLSSYIF"
     J_segment       410..447
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          157 c          125 g          112 t
ORIGIN      
        1 acatgggagc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccgggca gagagtcacc atctcctgca
      181 ctgggagcag ctccaacatc ggggcgggtt attctgtatc ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctatgaaa ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcgttgga ctccaatctg
      361 aggatgaggc tgattatttc tgctcagtct gggatagcag cctgagtagt tacatcttcg
      421 gtactgggac ccggctcacc gtcctaggtc agcccaaggc ttcccccacg gtcactctgt
      481 tcccg
//
LOCUS       KCVO01001681             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:12710:17298
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001681
VERSION     KCVO01001681.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12710:17298"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..434
                     /note="immunoglobulin light chain variable region"
     V_region        106..434
     V_segment       106..400
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73710.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       401..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>474
                     /gene="IGLC"
BASE COUNT           87 a          155 c          123 g          109 t
ORIGIN      
        1 acatgggggt gggatctcag gaggcagcac tctcaggacg tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagtctccct ctgtgtctgg gtctcctgga cagtcggtca ccatttcctg cactggaacc
      181 agcagtgaca ttggtgatta taaccgtgtc tcctggtacc aacagcaccc aggcaaagcc
      241 cccaaactca tgatttatga ggtcagtaat cggccctcag gggtctctga tcgcttctct
      301 ggttccaagt ctggcaacac ggcctccctg atcatctctg ggctccaggc tgaggacgag
      361 gctgattatt actgcagctc atacacaagc agtagcactt gggtattcgg cggagggacc
      421 cggctgaccg tccttggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001682             312 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:15623:17787
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001682
VERSION     KCVO01001682.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 312)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 312)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:15623:17787"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    33..274
                     /note="immunoglobulin light chain variable region"
     V_region        33..274
     V_segment       33..240
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <202..>246
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73711.1"
                     /translation="DFYCSSTDSSGNHVF"
     J_segment       244..274
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        275..>312
                     /gene="IGLC"
BASE COUNT           64 a           92 c           88 g           68 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca cggccagaaa aatatgctta ttggttccag
       61 cagaagccag gccagtcccc tgtgttgatc atcaatgagg acagcaaacg gccctctggg
      121 atccctgaga gattctctgg ctccagctcc gggacagtgg ccaccttgac tctcagtggg
      181 gcccaggtgg aggatgaagc tgacttctac tgttcctcaa cagatagtag tggtaatcat
      241 gtcttcggcg gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      301 actctcttcc cg
//
LOCUS       KCVO01001683             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:18585:11517
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001683
VERSION     KCVO01001683.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:18585:11517"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73712.1"
                     /translation="DYFCEVWDSSLSGRVF"
     J_segment       392..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           86 a          147 c          127 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcctc
       61 ctcacccttc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcagcgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaag
      181 attggagtta ataatgtata ttggtaccag cagttgccag gaacggcccc caaactcctc
      241 atttatgata gtaatcagcg accctcaggg gtccctgacc gattctctgg ctccaagtct
      301 ggcacgtcag cctccctggc catctgtggg ctccggcccg aggatgaggc tgattatttc
      361 tgcgaagtat gggatagcag cctgagcggt cgggtattcg gcggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001684             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:14858:8117
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001684
VERSION     KCVO01001684.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14858:8117"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73713.1"
                     /translation="DYYCSSYADTYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          157 c          120 g          113 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtacttata actatgtctc ctggtaccaa cagcatccag gcagagcccc
      241 caaactcatg atttttgagg tcagtgagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg cggacgaggc
      361 tgattattac tgttcctcat atgcagacac ctacactttt gtgtttggag gtggcaccag
      421 attgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01001685             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:16203:5142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001685
VERSION     KCVO01001685.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16203:5142"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..452
                     /note="immunoglobulin light chain variable region"
     V_region        130..452
     V_segment       130..417
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73714.1"
                     /translation="DYYCQVWDFSGDHNIF"
     J_segment       419..452
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        453..>492
                     /gene="IGLC"
BASE COUNT           97 a          157 c          138 g          100 t
ORIGIN      
        1 acatggggaa gaggcctggg aggaacctgc ccagcctggg cctcaggagg cagcattgac
       61 ggtgcctcag ccatgacctg gacttttctc ctcctcggcc tccttgctta ctgcacaggc
      121 tctgcggcct cctctgagct gactcagcca ccctcggtgt cagtgtcccc aggacagacg
      181 gccagaatca cctgtgggag agacaacatt ggaaataaga atgtgcactg gtaccagcag
      241 cggccaccgc gggcccctat actggtcatc tattatgata ccgaacggcc ctcagggatc
      301 cctgagcgat tctctggctc cacatcaggg aacaccgcca ccctgaccat cagcggggtc
      361 gaggccgggg atgaggctga ctattactgt caggtgtggg actttagtgg tgatcataac
      421 atcttcgatg ctgggacccg gctcaccgtc ctcggtcagc ccaaggcttc ccccacggtc
      481 actctgttcc cg
//
LOCUS       KCVO01001686             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:22747:7856
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001686
VERSION     KCVO01001686.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:22747:7856"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73715.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          151 c          121 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcctc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtactgac tcagcctccc
      121 tcagcgtctg aggccgccgg gaagagtgtc accatctcct gttctggaag cacctccaac
      181 atcggaagta acagtgtgtc ctggtacctg cagctcccag aaacggctcc caaactcctc
      241 atctattata atgatcggcg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcccgtcag cctccctggc catcagtggg ctcgagaccg aagatgaggc tgattattac
      361 tgcgcagtat gggatgatag cctgagcggt gtgttattcg gaggagggac ccgactgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001687             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:18351:18614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001687
VERSION     KCVO01001687.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18351:18614"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73716.1"
                     /translation="DYYCGSYTSSSTWVF"
     J_segment       402..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           85 a          156 c          125 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc gtgatttatg aggtcagtaa tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcggct catacacaag cagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001688             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:13867:8485
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001688
VERSION     KCVO01001688.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:13867:8485"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73717.1"
                     /translation="DYYCQVWDITTDHDVF"
     J_segment       389..425
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           95 a          139 c          131 g           98 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatgacct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ttctgcggcc tcctatgagc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaaa aatgtgcact ggtaccagca gaagccaccg caggcccctg tactggtcat
      241 ctactatgat agcgaacggc cctcagggat ccctgagcga ttctctggcg ccaaatcagg
      301 gaacaccgcc accctgagca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattacta ctgatcatga tgtgttcgga agtggcacca agttgaccgt
      421 cctcggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01001689             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:21986:10569
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001689
VERSION     KCVO01001689.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:21986:10569"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..429
                     /note="immunoglobulin light chain variable region"
     V_region        106..429
     V_segment       106..380
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73718.1"
                     /translation="DYYCQVRDSYSDQWVF"
     J_segment       393..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          148 c          140 g           90 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagcctctgc ggtcgcctat gagctgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taaaagtgtg cagtggtacc aacagaagcc gccgcaggcc cctatactgg
      241 tcatctatgt taatagcgag cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accattagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gcgggacagt tacagtgatc aatgggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001690             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:10196:3998
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001690
VERSION     KCVO01001690.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10196:3998"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73719.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           84 a          152 c          123 g          113 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttttg agcatgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcttg atttatgagg tcagttatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct gccaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattat tgcagctcat acacaagtag tagtacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001691             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:17891:10031
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001691
VERSION     KCVO01001691.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:17891:10031"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73720.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       413..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          156 c          131 g          109 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggaccccg ggcagagggt caccatctcg
      181 tgcactggga gcagctccaa cattggaggt tattttgtat actggtacca gcagttccca
      241 ggaacagccc ccaaattcct catctatgac aatagtaagc gaccctcagg gatttctgac
      301 cgattctctg gctccaagtc tggtacctca gcctccctga ccatcactgg gctccagcct
      361 ggggatgagg ctgattatta ctgcggagca tgggatagca gcctgagtgc tcgcttattc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01001692             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:16535:19202
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001692
VERSION     KCVO01001692.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16535:19202"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73721.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           83 a          157 c          121 g          114 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtactt ataactatgt ctcctggtac caacagcatc caggcacagc
      241 ccccaaactc atgatttttg aggtcagtga gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgttgct catatgcaga cacctacact tttgtgtttg gaggtggcac
      421 cagattgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001693             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:18300:18793
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001693
VERSION     KCVO01001693.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18300:18793"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73722.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       377..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           90 a          140 c          118 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaagtatg
      181 cttattggtt ccagcaaaag ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 gacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag ggggaggatg aagctgacta ctactgttat tcaatggata
      361 gtagtggtac tcagagcatc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001694             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:14132:8844
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001694
VERSION     KCVO01001694.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:14132:8844"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73723.1"
                     /translation="DYYCAAWDDSLSSPLF"
     J_segment       409..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           92 a          154 c          122 g          113 t
ORIGIN      
        1 acatggggac cttcagctgc gggtacagaa ggcaggactc aggataatct ccagcatggc
       61 ctggttccct ctcgtcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag ccaccctcaa cgtctggggc tcccgggcag agtgtcacca tctcttgctc
      181 tggaagcagt ttcaacattg gaagtaatta tgtaaactgg taccagcagc tcccaggaac
      241 ggcccccaaa ctcctcatct attttagtaa tcagcggccc tcaggggtcc ctgaccgatt
      301 ctctggctct aagtctggca cctcagcctc cctggccatc actggtctcc gatctgagga
      361 tgaggctgat tattactgtg cagcatggga tgatagtctg agcagtccct tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01001695             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:19612:14639
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001695
VERSION     KCVO01001695.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19612:14639"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    76..421
                     /note="immunoglobulin light chain variable region"
     V_region        76..421
     V_segment       76..382
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73724.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       385..421
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           85 a          156 c          115 g          103 t
ORIGIN      
        1 acatggggcg tgtccaccat ggccctgact cctctcctcc tcctgctcct ctctcactgc
       61 acaggttccc tctcccagcc tgtgctgact cagccaccct ccctgtctgc atccccggga
      121 gcatcggcca gactcccctg caccctgagc agtgacctca gtgttggtag taaaaacatg
      181 tactggtacc agcagaagcc agggagcgct cccaggttat tcctgtacta ctactccgac
      241 tcagacaagc agctgggacc tggggtcccc aatcgagtct ctggctccaa ggagacctca
      301 agtaacacag cgtttttgct catctctggg ctccagcctg aggacgaggc cgattattac
      361 tgtcaggtgt atgacagtac tggagtgttg ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001696             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:10981:7158
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001696
VERSION     KCVO01001696.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10981:7158"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..372
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73725.1"
                     /translation="DYHCFSTDSSGNRRGLF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           91 a          143 c          118 g          100 t
ORIGIN      
        1 tcaggaggca gagcgctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gacgacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcaggaaca gtggccacct
      301 tgactatcat tggggcccag gtggaggatg aagctgacta ccactgtttc tcaacagata
      361 gcagtggtaa tcgtaggggc ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001697             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:12092:4764
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001697
VERSION     KCVO01001697.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12092:4764"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73726.1"
                     /translation="DYYCSSTDSSGSYVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           89 a          141 c          118 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtact gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gggagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagaca
      361 gtagtggtag ttatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001698             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:14208:11100
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001698
VERSION     KCVO01001698.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14208:11100"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73727.1"
                     /translation="DYYCQVWDSSSDHILF"
     J_segment       396..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           87 a          145 c          138 g           98 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acaggctctg cggtctccta tgagttgact
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 aaccttggag ataaatatgt acactggtac cagcagaagc caccgcgggc ccctgtgctg
      241 gtcatctact atgatagtga ccggccctca tggatccctg agcgattctc tgggtccaaa
      301 tcagggatca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag tagtagtgat catatcttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001699             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:13309:6899
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001699
VERSION     KCVO01001699.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13309:6899"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73728.1"
                     /translation="DYYCAAWDDRLNSPFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          152 c          117 g          106 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaac
      181 attggaagta attatgtaaa ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 atctattttg ataatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcggcat gggatgacag gttgaacagt cccttcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001700             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:8180:16078
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001700
VERSION     KCVO01001700.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:8180:16078"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73729.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       379..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           91 a          140 c          115 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaagtatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaagacgaca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcatggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaatagata
      361 gtagtggtag tcatagcgtc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001701             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:22151:17687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001701
VERSION     KCVO01001701.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:22151:17687"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73730.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           96 a          145 c          125 g           98 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccatcctc actttctgca caggctctgc agcctcctat gagctgacac
      121 agccaccctc gttgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg
      181 cattgccaga aaaatatgct tattggtacc agcagaaacc aggccagtcc cctatgctga
      241 tcatctgtga ggacagcaaa cggccctctg ggatccctga aagattctct ggctccagct
      301 cagggacagt ggccaccttg actatcactg gggcccaggt ggaggatgaa gctgactact
      361 actgttactc agcagacaac agtggtcagg gctcattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001702             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:10008:16042
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001702
VERSION     KCVO01001702.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10008:16042"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73731.1"
                     /translation="DYYCQVWDSSSKYAIF"
     J_segment       396..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           91 a          149 c          136 g           90 t
ORIGIN      
        1 acatgggggc tgggtctcag gaggcagcat tgacggtgcc tcagccatgg cctggaccct
       61 tctcctcctc ggcctcctcg ctcactgcac aggctctgcg acctcctatg aggtgactca
      121 gccaccctcg gtgtcagcgg cctcaggaca gacggccagg atcacctgtg ggggagacaa
      181 cattggaagt agaaatgtcc actggtacca gcagaagcca cctcaggccc ctgttctggt
      241 catctatgct gatgccaaac ggccctcagg gatccctgag cgattctctg gctccaactc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta gtagtaaata cgcgatattc ggcggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001703             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:5815:11985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001703
VERSION     KCVO01001703.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:5815:11985"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..405
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73732.1"
                     /translation="DYYCQSYDTRLRAWVF"
     J_segment       406..442
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           90 a          156 c          125 g          109 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtc
      121 ctgacgcagc cgccctcagt gtctggggcg cccggacaga gggtcaccat ctcctgctct
      181 gggagcagct ccaacattgg agattatttt gtgcagtggt accaacagct tccaggaacg
      241 gcccccaaac tcctcatcta tgaaaatgat aaacggccct caggagtttc tgatcgattc
      301 tctggctccc agtctggaac ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgcca gtcctatgac accagattga gggcttgggt attcggcggt
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001704             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:20414:15203
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001704
VERSION     KCVO01001704.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20414:15203"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73733.1"
                     /translation="DYYCSSTDSRDNHRVF"
     J_segment       390..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           96 a          142 c          126 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatacttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc acgttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagcaggg ataatcatag ggtattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001705             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:18984:15507
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001705
VERSION     KCVO01001705.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:18984:15507"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73734.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          138 c          142 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagattctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcattggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttgtactgg
      241 tcatctatgg tgatagggaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001706             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:17608:5945
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001706
VERSION     KCVO01001706.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:17608:5945"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73735.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          155 c          124 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtaatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001707             388 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:9019:7829
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001707
VERSION     KCVO01001707.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 388)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:9019:7829"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    140..350
                     /note="immunoglobulin light chain variable region"
     V_region        140..350
     V_segment       140..310
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <275..>322
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73736.1"
                     /translation="DYYCYSTVSSGNERIF"
     J_segment       317..350
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        351..>388
                     /gene="IGLC"
BASE COUNT           72 a          124 c          105 g           87 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggccagtc ccctgtgctg atcatctatg aggacagcaa
      181 acggccctct gggatccctg agagactctc tggctccagc tcagggacag tggccacctt
      241 gactatcagt ggggcccagg tggaggatga agctgactac tactgttact caacagttag
      301 tagtggtaat gaaaggatct tcggtgctgg gacccggctc accgtcctag gtcagcccaa
      361 ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCVO01001708             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:9266:17992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001708
VERSION     KCVO01001708.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:9266:17992"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73737.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       413..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           92 a          158 c          128 g          109 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcaccatctc
      181 ctgcactggg agcagctcca acattggagg ttattatgtg cagtggtacc agcagcttcc
      241 aggaacggcc cccaaactcc tcatatatga aaataataag cgaccctcag gggtttctga
      301 tcgattctct ggctcccagt ctggtacctc agcctccctg accatcactg gactccagtc
      361 tgaggatgag gctgattatt actgccagtc ctatgacagc agcctgagtg ccgtgttatt
      421 cggagcaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCVO01001709             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:8094:10484
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001709
VERSION     KCVO01001709.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8094:10484"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73738.1"
                     /translation="DYYCSSTDRSGNHVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          142 c          125 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccaaca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac agcaaacggc cctctgggat tcctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaggctg actactactg
      361 ttcctcaaca gatagaagtg gtaatcatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001710             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:17934:4985
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001710
VERSION     KCVO01001710.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17934:4985"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73739.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          143 c          139 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gtgggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga acgattctct ggctccaaat
      301 cagggagcgc cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001711             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:26774:10784
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001711
VERSION     KCVO01001711.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:26774:10784"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73740.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           87 a          159 c          119 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttcaaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001712             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:16339:15914
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001712
VERSION     KCVO01001712.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16339:15914"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73741.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          144 c          126 g          103 t
ORIGIN      
        1 acaggggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ttctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgacgac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcattggggc ccaggtggag gatgaagctg actaccactg
      361 tttctcaaca gatagcagtg gtaatcatag gggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001713             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:21058:14767
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001713
VERSION     KCVO01001713.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21058:14767"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73742.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       395..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           87 a          143 c          139 g           97 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gtctcctatg acctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg tgggagacaa
      181 tgttggaagt gaatatgtgc actggtacca acagaagcca ccgcaggccc ctgtggtggt
      241 catccattat aatagtgacc ggccctcagg gatccctgaa cgattctctg gctccaaatc
      301 agggagcgcc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta gtagtgatca tagtttattg ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001714             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:14170:17338
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001714
VERSION     KCVO01001714.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:14170:17338"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73743.1"
                     /translation="DYYCSSTDRSGNHVF"
     J_segment       387..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           93 a          143 c          123 g           99 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtccccc ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 cagaaaaata tgcttattgg ttccaacaga agccaggcca gtcccctgtg ctgatcatca
      241 atgaggacag caaacggccc tctgggattc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactctc agtggggccc aggtggagga tgaagctgac tactactgtt
      361 cctcaacaga tagaagtggt aatcatgtat tcggcggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001715             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:11991:13424
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001715
VERSION     KCVO01001715.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:11991:13424"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..404
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73744.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       406..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           89 a          155 c          128 g          108 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagtt ccaacattgg aggttattat gtgcagtggt accagcagct tccaggaacg
      241 gcccccaaac tcctcatgta tgaaaataat aagcgaccct caggggtttc tgatcgattc
      301 tctggctccc agtctggtac ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgcca gtcctatgac agcagcctga gtgccgtgtt attcggagca
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001716             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1101:13420:7866
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001716
VERSION     KCVO01001716.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:13420:7866"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73745.1"
                     /translation="DYYCFSTESSVNHRVLF"
     J_segment       394..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           96 a          140 c          124 g          106 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggatccagca gaagccaggc cagtcccctg ttctgatcat
      241 ctatgaagac aggaaacggc cctctgggat ctctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 tttctcaaca gaaagtagtg ttaatcatag ggtcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001717             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:19557:7469
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001717
VERSION     KCVO01001717.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19557:7469"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73746.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          139 c          142 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgcg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gtattggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttgtgctgg
      241 tcatgtatgg tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cagggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001718             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:9963:19486
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001718
VERSION     KCVO01001718.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:9963:19486"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73747.1"
                     /translation="DYYCQVWDSSSDVFF"
     J_segment       396..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          142 c          139 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcattggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttgtactgg
      241 tcatctatgc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tattcttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001719             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:16677:9679
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001719
VERSION     KCVO01001719.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16677:9679"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73748.1"
                     /translation="DYYCSSYASSSTWIF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           89 a          156 c          121 g          107 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat aatttatgag gtcagtgatc gaccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacgcaagca gtagcacttg gatattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001720             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:6443:4644
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001720
VERSION     KCVO01001720.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:6443:4644"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..422
                     /note="immunoglobulin light chain variable region"
     V_region        104..422
     V_segment       104..385
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73749.1"
                     /translation="DYWCQSTDSSGFIF"
     J_segment       388..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           99 a          134 c          124 g          103 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 accaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aattatggtc agtggttcca gcagaagccg ggccaggccc ctgtgttgct
      241 gatatataaa gacagtgaga ggccctcagg gatccctggg cgattctcta gctccagttc
      301 agggacatca attaccttga ccatcagtgg ggcccaggca gaggatgagg ctgactattg
      361 gtgtcaatca acagacagca gtggtttcat cttcggtgct gggacccgac tcaccgtcct
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01001721             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:12321:11649
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001721
VERSION     KCVO01001721.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12321:11649"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73750.1"
                     /translation="DYFCSSYTASSTWVF"
     J_segment       400..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           83 a          156 c          122 g          112 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtaatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctgt tcatctctgg gctcctggct gaggacgagg
      361 ctgattattt ctgcagctca tacacagcca gtagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001722             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:15805:9045
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001722
VERSION     KCVO01001722.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:15805:9045"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73751.1"
                     /translation="DYYCSSFASSSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          155 c          123 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa caacacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtaatcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgat catctctggg ttccaggctg aggacgaggc
      361 tgattattac tgcagctcat tcgcaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001723             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:13901:10142
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001723
VERSION     KCVO01001723.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13901:10142"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73752.1"
                     /translation="DYYCSSYAGTSTWVF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          155 c          125 g          107 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata atcgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcata atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgag catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaggcac tagcacttgg gtattcggcg gggggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001724             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:24234:6841
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001724
VERSION     KCVO01001724.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:24234:6841"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..380
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73753.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       383..420
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           86 a          137 c          138 g           97 t
ORIGIN      
        1 acatgggggc ctcgggaagc agccttggcg gtgcctcagc catggccggg acccttctcc
       61 tcctcggcct ccttgctcac tgcacagagt ttgtggtctc ctatgaattg actcagccac
      121 gctcagtgtc cgtgtcccca ggacagacgg ccaggatcac ctgtggggga gacagcattg
      181 gaagtagaag tgtgcagtgg tatcagcaga agccaccgca ggcccttcta ctggtcatct
      241 atgctgatag cgaacggccc tcagggatcc ctgagcgatt ctctggctcc aatttaggga
      301 acaccgccac cctgaccatc agcggcgtcg aggccgggga tgaggctgac tattactgtc
      361 aggtgtggga cagtagtagt gatgtgttat tcggaggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001725             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:5680:5130
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001725
VERSION     KCVO01001725.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:5680:5130"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73754.1"
                     /translation="DYYCSSYTSSSTWLF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           86 a          155 c          122 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagcacttgg ttattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001726             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:10817:14191
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001726
VERSION     KCVO01001726.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:10817:14191"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73755.1"
                     /translation="DYYCSSYTSSRTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           88 a          151 c          124 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca gtggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagaacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattat tgcagctcat acacaagcag tagaacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001727             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:16229:8240
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001727
VERSION     KCVO01001727.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:16229:8240"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73756.1"
                     /translation="DYYCQSGDSSANHYIF"
     J_segment       392..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          104 a          137 c          122 g          103 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatgctc ggtggttcca gcagaagcca ggccaggccc ctgtgttggt
      241 gatatataaa gacactgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacaata cttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca ggagacagca gtgctaatca ttacatcttc ggtgctggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCVO01001728             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:20410:9806
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001728
VERSION     KCVO01001728.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20410:9806"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73757.1"
                     /translation="DYYCSSYASSSTWIF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          157 c          123 g          107 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc ataatttatg aggtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacgcaag cagtagcact tggatattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001729             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:14885:15537
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001729
VERSION     KCVO01001729.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:14885:15537"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..431
                     /note="immunoglobulin light chain variable region"
     V_region        104..431
     V_segment       104..399
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73758.1"
                     /translation="DYYCSSYVVGNTLF"
     J_segment       400..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           85 a          153 c          120 g          111 t
ORIGIN      
        1 acatgggggg ggtctcagga ggcagcgctc tcaggacgtc tccaccatgg tctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctct gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaatcag
      181 caatgacatc ggtggttata actatgtctc ctggtaccag cagcacccag gcaaagcccc
      241 caaattcatg atttttgatg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaaatct ggcaacacgg cctccctgac catctctggc ctccaggctg aggatgaggc
      361 tgattattac tgcagctcat atgttgtagg caacacttta ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001730             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:2141:9956
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001730
VERSION     KCVO01001730.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:2141:9956"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73759.1"
                     /translation="DYYCSSTDTTGNHRVLF"
     J_segment       394..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           94 a          147 c          123 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tccaatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaggccaggc cagtcccctg tcctgatcat
      241 ctatgaagac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gataccactg gtaatcatag ggtcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001731             344 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:20507:11633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001731
VERSION     KCVO01001731.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 344)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:20507:11633"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..306
                     /note="immunoglobulin light chain variable region"
     V_region        8..306
     V_segment       8..269
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>278
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73760.1"
                     /translation="DYYCQVWDSSSNHILF"
     J_segment       272..306
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        307..>344
                     /gene="IGLC"
BASE COUNT           74 a           96 c          104 g           70 t
ORIGIN      
        1 acatgggggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaacc
       61 ttggagataa atgtatacac tggtaccagc agaagccagc gcgggcccct gtgctggtca
      121 tctactatga tagtgaccgg ccctcatgga ttcctgagcg attctctggg tccaaatcag
      181 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      241 gtcaggtgtg ggacagtagt agtaatcata tcttattcgg aggagggacc cggctgaccg
      301 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001732             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:15369:17232
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001732
VERSION     KCVO01001732.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:15369:17232"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..394
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73761.1"
                     /translation="DYYCCSYAARYLF"
     J_segment       395..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           82 a          160 c          122 g          102 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccac
      181 cagtgacatc ggtggctcta actatgtctc ctggtaccaa cagcatccag gcacagcccc
      241 caaattcatg atttatgagg tcagtaagcg gccctcaggg gtctcgaatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgctgctcat atgcagccag gtacttattc ggaggcggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001733             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:5077:5177
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001733
VERSION     KCVO01001733.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:5077:5177"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..399
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73762.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       402..438
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           88 a          160 c          122 g          106 t
ORIGIN      
        1 acatgggggt ggcctcagag gtagccgtgt ccaccatggc cctgactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cccagcctgt gctgactcag ccaccctccc
      121 tgtctgcatc cccgggagca tcggccagac tcccctgcac cctgagcagt gacctcagtg
      181 ttggtagtaa aaacatgtac tggtaccagc agaagccagg gagcgctccc aggttattcc
      241 tgtactacta ctccgactca gacaagcagc tgggacctgg ggtccccaat cgagtctctg
      301 gctccaagga gacctcaagt aacacagcgt ttttgctcat ctctgggctc cagcctgagg
      361 acgaggccga ttattactgt caggtgtatg acagtactgg agtgttgttc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001734             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:3684:9590
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001734
VERSION     KCVO01001734.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:3684:9590"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..428
                     /note="immunoglobulin light chain variable region"
     V_region        107..428
     V_segment       107..388
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73763.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       395..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           89 a          140 c          140 g           97 t
ORIGIN      
        1 acatgggggg agcctggcct cgggaagcag ccttggcggt gcctcagcca tggccgggac
       61 ccttctcctc ctcggcctcc ttgctcactg cacagactct gtggtctcct atgaattgac
      121 tcagccacgc tcagtgtccg tgtccccagg acagacggcc aggatcacct gtgggggaga
      181 cagcattgga agtagaagtg tgcagtggta ccagcagaag ccaccgcagg cccttatatt
      241 ggtcatctat gctgatagcg aacggccctc agggatccct gagcgattct ctggctccaa
      301 tttagggaac accgccaccc tgaccatcag cggcgtcgag gccggggatg aggctgacta
      361 ttactgtcag gtgtgggaca gtagtagtga tgtattattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001735             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:13555:17182
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001735
VERSION     KCVO01001735.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13555:17182"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73764.1"
                     /translation="DYYCQVWDSITDHSIF"
     J_segment       395..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           86 a          149 c          134 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagtctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggggaca
      181 acattggaac tgaatatgtg cactggtacc agcagaagcc accgcaggcc cctgtggtgg
      241 tcatctatta taatactgac cggccctcag ggatccctgg gcgattctca ggctccaaat
      301 cagggaacac cggcaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt attactgatc attccatctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01001736             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:7717:10770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001736
VERSION     KCVO01001736.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:7717:10770"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73765.1"
                     /translation="DYYCFSSDSSADYWVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           89 a          142 c          126 g          106 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac accaaacggc cctctgggat ccctgagaga ttctctggtt ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggat gatgaagctg actactactg
      361 tttctcatca gatagcagtg ctgattattg ggtgttcggc ggagggaccc ggctgaccgt
      421 cccaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001737             451 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:25648:5956
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001737
VERSION     KCVO01001737.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 451)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:25648:5956"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..413
                     /note="immunoglobulin light chain variable region"
     V_region        83..413
     V_segment       83..377
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73766.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       378..413
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>451
                     /gene="IGLC"
BASE COUNT           83 a          153 c          111 g          104 t
ORIGIN      
        1 acatggggac tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctca ctcaggctgc cctgactcag tctccctctg tgtctgggtc
      121 tcctggacag tcggtcacca tttcctgcac tggaaccagc agtgacattg gtggttataa
      181 ccgtgtctcc tggtaccaac agcacccagg caaagccccc aaactcatga tttatgacgt
      241 cagtgatcgg ccctcagggg tctctgatcg cttctctggt tccaagtctg gcaacacggc
      301 ctccctgatc atctctgggc tccaggctga ggacgaggct gattattact gcagctcata
      361 cacaagcact accacttggc tattcggcgg agggacccgc ctgaccgtcc taggtcagcc
      421 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001738             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:18629:6086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001738
VERSION     KCVO01001738.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18629:6086"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..425
                     /note="immunoglobulin light chain variable region"
     V_region        102..425
     V_segment       102..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73767.1"
                     /translation="DYYCYSADSSSNHSFF"
     J_segment       391..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>464
                     /gene="IGLC"
BASE COUNT           94 a          146 c          121 g          103 t
ORIGIN      
        1 acatggggtg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccaaaaaa atatgcttat tggttccagc agaagccagg ccagtcccct gtgctgatca
      241 tctatgaaga caccaaacgg ccctctggga tccctgggag attctctggc tccagctcag
      301 ggacagtggc caccttgact atcagtgggg cccaggtgga ggatgaagct gactactact
      361 gttactcagc cgatagcagt tctaatcata gcttcttcgg aggagggacc cggctgaccg
      421 tcctaagtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001739             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:14668:5059
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001739
VERSION     KCVO01001739.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14668:5059"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73768.1"
                     /translation="DYYCQVWDSSSDVFF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          140 c          138 g           99 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagact
      181 tcattggaag tagaagtgtg cagtggtacc aacagaagcc accgcaggcc cttgtactgg
      241 tcatctatgg tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaatac cgccaccctg accatcaacg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttcttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001740             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:23405:13578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001740
VERSION     KCVO01001740.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:23405:13578"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73769.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           97 a          144 c          121 g           98 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggtaccagca gaaaccaggc cagtccccta tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgaaaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcactggggc ccaggttgag gatgaagctg actactactg
      361 ttactcagca gacaacagtg gtcagggctc attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001741             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:19388:6873
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001741
VERSION     KCVO01001741.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:19388:6873"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..419
                     /note="immunoglobulin light chain variable region"
     V_region        104..419
     V_segment       104..385
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73770.1"
                     /translation="DYYCQSTDSSGFIF"
     J_segment       388..419
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>460
                     /gene="IGLC"
BASE COUNT          101 a          138 c          119 g          102 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 accaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aaatatgctc cgtggttcca gcagaagcca ggccaggccc ctgtgttgct
      241 gatatttaaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacatca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca acagacagca gtggtttcat cttcggtgct gggacccggc tcaccgtccc
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01001742             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:5485:12245
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001742
VERSION     KCVO01001742.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:5485:12245"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..443
                     /note="immunoglobulin light chain variable region"
     V_region        116..443
     V_segment       116..404
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <371..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73771.1"
                     /translation="DYYCQSHDTGLKTLF"
     J_segment       410..443
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           92 a          158 c          120 g          111 t
ORIGIN      
        1 acatggggct ctgcttcatc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctcgtct cctctcctcc tcacccttct cattcactgc acagggtcct gggcccagtc
      121 tgtgctgaca cagccgccct cagtgtctgg ggccccaggg cagagggtca ccatctcctg
      181 cactgggggc agctccaaca ttggagctta ttatgtatac tggtaccagc agttcccagg
      241 aatggccccc aaactcctca tctatgacaa taataagcga ctgtcagggg tttctgaccg
      301 attctctggc tccaagtctg gttcctcagc ctccctgacc atcactgggc tccagactga
      361 ggatgaggct gattattact gccagtccca tgacactggc ctgaaaactt tattcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01001743             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:16588:2371
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001743
VERSION     KCVO01001743.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:16588:2371"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73772.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       399..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           91 a          147 c          130 g           99 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gaactgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaga taaatatcta cactggtatc atcagaagcc agcgcaggcc cctgtgctgg
      241 tcatctacta tgatactgac cggccctcat ggatccctga gcgattctct ggatccaagt
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggcgatgag gctgactatt
      361 actgtcaggt gtgggacagt aataatgatc atatcttttt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001744             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:23826:3975
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001744
VERSION     KCVO01001744.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:23826:3975"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73773.1"
                     /translation="DYYCQVWDSSTNHILF"
     J_segment       392..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          144 c          135 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgtggt ctcctatgag ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaacc
      181 ttggagataa atatgtacac tggtaccagc agaagccagc gcgggcccct gtgctggtca
      241 tctactatga tagtgaccgg ccctcatgga tccctgagcg attctctggg tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt actaatcata tcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001745             421 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:21188:13630
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001745
VERSION     KCVO01001745.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 421)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:21188:13630"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    53..383
                     /note="immunoglobulin light chain variable region"
     V_region        53..383
     V_segment       53..347
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <311..>355
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73774.1"
                     /translation="DYYCSSYAGTSTWVF"
     J_segment       348..383
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        384..>421
                     /gene="IGLC"
BASE COUNT           77 a          132 c          109 g          103 t
ORIGIN      
        1 acatggggga ctcactgaag tgtgtttctc cctctttcca ggatcctggg ctcaggctgc
       61 cctgactcag tctccctctg tgtctgggtc tcctggacag tcggtcaccg tttcctgcac
      121 tggaaccagc agtgacattg gtgattataa ccgtgtctcc tggtaccaac agcacccagg
      181 caaagccccc aaactcataa tttatgaggt cagtaatcgg ccctcagggg tctctgatcg
      241 cttctctggt tctaagtctg gcaacacggc ctccctgagc atctctgggc tccaggctga
      301 ggacgaggct gattattact gcagctcata cgcaggcact agcacttggg tattcggcgg
      361 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      421 g
//
LOCUS       KCVO01001746             533 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:20604:4220
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001746
VERSION     KCVO01001746.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 533)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 533)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..533
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:20604:4220"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    162..495
                     /note="immunoglobulin light chain variable region"
     V_region        162..495
     V_segment       162..455
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <417..>467
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73775.1"
                     /translation="DYYCLSYDSSLSAHYIF"
     J_segment       458..495
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        496..>533
                     /gene="IGLC"
BASE COUNT          109 a          169 c          138 g          117 t
ORIGIN      
        1 acatggggac tctcagagta tgaagaagga ggggcaggga gagatttggg gaagctctgc
       61 ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc tcgtctcctc
      121 tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg ctgacacagc
      181 caccctcagt gtctggggcc ccagggcaga gggtcaccat ctcgtgcact gggagcagct
      241 ccagcattgg aggtgattat gtttcctggt accaacagct cccaggaatg acccccaaac
      301 tcctcatcta tcaaaataat aagcgaccct caggggtatc tgaccgattc tctggctcca
      361 agtctggtac ctcagcctcc ctgaccatca ctgggctcca gactgaggat gaggctgatt
      421 actactgcct gtcctatgac agcagcctga gtgctcatta catcttcggt cctgggaccc
      481 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001747             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:9095:20365
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001747
VERSION     KCVO01001747.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:9095:20365"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..389
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73776.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           89 a          153 c          120 g          103 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac gcagccgccc
      121 tcagtgtctg gggcgcccgg gcagagggtc accatctcct gcactgggag tacctccaac
      181 attggaggtt attatgtgca gtggtaccag cagcttccaa gaacggcccc caaactcctc
      241 atctatgaaa ataataagcg accctcaggg gtttctaatc gattctctgg ctcccagtct
      301 ggtgcctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgactattac
      361 tgccagtcct atgacagcag cctgagtgcc gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001748             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:11706:12584
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001748
VERSION     KCVO01001748.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:11706:12584"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73777.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          143 c          139 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gtgggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga acgattctct ggctccaaaa
      301 cagggagcgc cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001749             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:14030:20147
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001749
VERSION     KCVO01001749.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14030:20147"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73778.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       391..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           87 a          141 c          138 g           96 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggtct cctatgacct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtgtggg agacaatgtt
      181 ggaagtgaat atgtgcactg gtaccaacag aagccaccgc aggcccctgt ggtggtcatc
      241 cattataata gtgaccggcc ctcagggatc cctgaacgat tctctggctc caaatcaggg
      301 agcgccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtagtag tgatcatagt ttattgggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001750             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:22660:12163
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001750
VERSION     KCVO01001750.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:22660:12163"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73779.1"
                     /translation="DYYCSSRDSSGNYVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           91 a          140 c          127 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgtatt
      181 gccagaaaaa tttgcttatt ggttccaaca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac agcaagcggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaaggtg actactactg
      361 ttcctcaaga gatagcagtg gtaattatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001751             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:11461:14661
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001751
VERSION     KCVO01001751.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:11461:14661"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73780.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          162 c          125 g          107 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actcccttcc
      481 cg
//
LOCUS       KCVO01001752             317 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:19746:14485
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001752
VERSION     KCVO01001752.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 317)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:19746:14485"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    3..279
                     /note="immunoglobulin light chain variable region"
     V_region        3..279
     V_segment       3..242
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <204..>251
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73781.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       247..279
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        280..>317
                     /gene="IGLC"
BASE COUNT           69 a           85 c           98 g           65 t
ORIGIN      
        1 acatgggcag gatcacctgt gggggagaca atgttggaag tgaatatgtg cactggtacc
       61 aacagaaacc agcgcaggcc cctgtggtgg tcatccatta taatagtgac cggccctcag
      121 ggatccctga gcgattctct ggctccaaat cagggaacac cgccaccctg accatcagcg
      181 gggtcgaggc cggggatgag gctgactatt actgtcaggt gtgggacagt agtagtgatc
      241 attgtgtatt gggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct
      301 cggtcactct cttcccg
//
LOCUS       KCVO01001753             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:5833:18550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001753
VERSION     KCVO01001753.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:5833:18550"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..406
                     /note="immunoglobulin light chain variable region"
     V_region        87..406
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73782.1"
                     /translation="DYYCYSTDTSAYHVF"
     J_segment       375..406
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>446
                     /gene="IGLC"
BASE COUNT           89 a          140 c          116 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagta
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggtcacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagata
      361 ccagtgctta tcatgtattc ggcggaggga cccggctgac cgtcctgggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001754             420 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:17276:13529
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001754
VERSION     KCVO01001754.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 420)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17276:13529"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..382
                     /note="immunoglobulin light chain variable region"
     V_region        58..382
     V_segment       58..345
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <307..>354
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73783.1"
                     /translation="DYYCQVWDSSTDHTLL"
     J_segment       349..382
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        383..>420
                     /gene="IGLC"
BASE COUNT           83 a          128 c          120 g           89 t
ORIGIN      
        1 acatggggga cccttctcct cctcggcctc cttgcttact gcacaggctc tgcggtctcc
       61 tatgagctga ctcagccacc ctcggtgtca gtgtccccag gacagacggc caggatcacc
      121 tgtgggggag acaatgttgg aagtgaatat gtgcactggt accaacagaa gccaccgcag
      181 gcccctgtgg tggtcatcca ttataatagt gaccggccct cagggatccc tgagcgattc
      241 tctggctcca aatcagggaa caccgccacc ctgaccatca gcggggtcga ggccggggat
      301 gaggctgact attactgtca ggtgtgggac agtagtactg atcatacttt attgggagga
      361 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001755             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1101:19121:3972
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001755
VERSION     KCVO01001755.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:19121:3972"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..409
                     /note="immunoglobulin light chain variable region"
     V_region        87..409
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73784.1"
                     /translation="DYYCHSSDISGNHRVF"
     J_segment       376..409
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>449
                     /gene="IGLC"
BASE COUNT           91 a          139 c          117 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaagacagta
      241 aacggccctc tgggatccct gagagattct ctggctccag ttcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aggctgacta ctactgtcac tcatcagata
      361 tcagtggtaa tcatagggta ttcggcggag ggacccggct gaccgtcctt ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001756             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:22241:18519
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001756
VERSION     KCVO01001756.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22241:18519"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73785.1"
                     /translation="DYYCSSYADTTTWLF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           85 a          160 c          120 g          108 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgac gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacgcagaca ctaccacttg gctattcggc ggagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001757             395 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:5789:18203
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001757
VERSION     KCVO01001757.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 395)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:5789:18203"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    27..357
                     /note="immunoglobulin light chain variable region"
     V_region        27..357
     V_segment       27..321
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <285..>329
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73786.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       322..357
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        358..>395
                     /gene="IGLC"
BASE COUNT           71 a          121 c          106 g           97 t
ORIGIN      
        1 acatgggggg cacaggatcc tgggctcagg ctgccctgac tcagtctccc tctgtgtctg
       61 ggtctcctgg acagtcggtc accatttcct gcactggaac cagcagtgac attggtggtt
      121 ttgagcgtgt ctcctggtac caacagcacc caggcaaagc ccccaaactc ttgatttatg
      181 aggtcagtta tcggccctca ggggtctctg atcgcttctc tggttccaag tctgccaaca
      241 cggcctccct gatcatctct gggctccagg ctgaggacga ggctgattat tattgcagct
      301 catacacaag tagtagtact tgggtattcg gcggagggac ccggctgacc gtcctaggtc
      361 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001758             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:10944:20745
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001758
VERSION     KCVO01001758.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:10944:20745"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..392
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73787.1"
                     /translation="DYYCFVYYSGTQFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           99 a          153 c          116 g           97 t
ORIGIN      
        1 acatgggggg agccagagat cccttccaat accagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtggctc cagcactgga
      181 gcagtcacca gtggtaactt tccaaactgg ttccagcaga aacctggaca agtccccagg
      241 ggactgattt acaatacaaa caacaaacac tcctggaccc ctgcccggtt ctcaggctcc
      301 ctcgctgggg gcaaagctgc cctgacactg gcaggagcac agcccgagga cgaggctgat
      361 tattactgct tcgtgtacta tagtggtact caattcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001759             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:18981:19653
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001759
VERSION     KCVO01001759.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:18981:19653"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..372
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73788.1"
                     /translation="DYYCYSMDTSGTLSIF"
     J_segment       377..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           86 a          143 c          117 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc acgatcacct gctctggaga tgcattgcca aaaaagtttg
      181 cttattggtt ccagcagaag ccaggccagt cccctctgct gatcatctat gaggacagca
      241 gacggccctc tgggatccct gagagattct ctggctccag ttcagggaca gtggccgcct
      301 tgactatcag tggggcccag ggggaggatg aagctgacta ctactgttat tcaatggata
      361 ccagtggtac tctgagcatc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001760             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:26388:10739
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001760
VERSION     KCVO01001760.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:26388:10739"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73789.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          159 c          121 g          108 t
ORIGIN      
        1 acatgggggc agcttcagtt gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaactaat agtgtatcct ggtaccagca gctcccagaa
      241 acggctccca aactcctcat ctattataat gatcgacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gataacagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCVO01001761             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:8719:17908
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001761
VERSION     KCVO01001761.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8719:17908"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73790.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       390..420
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           90 a          138 c          124 g          106 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagtcac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 cagaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgtg ttgatcatta
      241 atgaggacag caaacggccc tctgggatcc ctgggagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactctc agtggtgccc aggtggagga tgaagctgac tactattgtt
      361 cctcaacaga tagtagtggt aattatgttt tcggcggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001762             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:14286:4637
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001762
VERSION     KCVO01001762.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14286:4637"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..421
                     /note="immunoglobulin light chain variable region"
     V_region        97..421
     V_segment       97..384
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <346..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73791.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       388..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           87 a          140 c          136 g           96 t
ORIGIN      
        1 acatggggct cgggaagcag ccttggcggt gcctcagcca tggccgggac ccttctcctc
       61 ctcggcctcc ttgcttactg cacaggctct gcggtctcct atgagctcac tcagccaccc
      121 tcggtgtcag tgtccccagg acagacggcc aggatcacct gtgggggagg caatgttgga
      181 agtgaatatg tccactggta tcaacagaag ccaccgcagg cccctgtggt ggtcatctat
      241 tataatactg accggccctc agggatccct gagcgattct ctggctccaa atcagggaac
      301 accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta ttactgtcag
      361 gtgtgggaca gtaggagtga tcatagttta ttgggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001763             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:3318:7841
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001763
VERSION     KCVO01001763.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:3318:7841"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73792.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           93 a          153 c          127 g          108 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcctcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcacc tccaacatcg gaagtaacag tgtgtcctgg tacctgcagc tcccagaaac
      241 ggctcccaaa ctcctcatct attataatga taggcgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggcc cgtcagcctc cctggccatc agtgggctcg agaccgaaga
      361 tgaggctgat tattactgcg cagtatggga tgatagcctg agcggtgtgt tattcggagg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01001764             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:12898:17902
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001764
VERSION     KCVO01001764.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:12898:17902"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..407
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73793.1"
                     /translation="DYYCQVYDSNTWVF"
     J_segment       408..444
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          164 c          119 g          109 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagagacc
      181 tcagtgttgg tagtaaaaac atgttctggt accagcagaa gccaggaagc gctcccaggt
      241 ttttcctgca ctactactcc gactcagaca accatctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tatatgacag taatacttgg gtattcggcg
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001765             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:10127:6380
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001765
VERSION     KCVO01001765.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10127:6380"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..436
                     /note="immunoglobulin light chain variable region"
     V_region        107..436
     V_segment       107..396
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73794.1"
                     /translation="DYYCSSYAGNNIALF"
     J_segment       403..436
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>475
                     /gene="IGLC"
BASE COUNT           85 a          160 c          125 g          105 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac caacaacatc caggcgcagc
      241 ccccaaagtc atgatctatg aggtcaatgt gcggccctca ggggtctctc atcgcttctc
      301 tggctccaag tctggcgaca cggcctccct gaccatctct gggctccagg ccgaggacga
      361 ggctgattat tactgcagct catatgcagg caacaatatt gccttatttg gaggagggac
      421 ccggctgacc gtcctacgtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001766             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:14231:7323
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001766
VERSION     KCVO01001766.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14231:7323"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73795.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           83 a          163 c          120 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accctttcct gcactggaac
      181 cagcagtgac attggtggtt ataaccgtgt ctcctggtac caacaccacc caggcaaagc
      241 ccccaaactc atgatttatg acgtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacgcaag cacttccact tggctattcg gcggagggac
      421 ccgcctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001767             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:18119:17710
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001767
VERSION     KCVO01001767.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18119:17710"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..453
                     /note="immunoglobulin light chain variable region"
     V_region        120..453
     V_segment       120..413
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73796.1"
                     /translation="DYYCQSYDSRLNPHVLF"
     J_segment       416..453
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           92 a          158 c          129 g          112 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagacg gtcaccatct
      181 cctgcactgg gagcagctcc aacattggag gttattatgt gcagtggtac cagcagcttc
      241 caggaacggc ccccaaactc ctcatgtatg aaaataataa gcgaccctca ggggtttctg
      301 atcgcttctc tggctcccag tctggtacct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag caggttgaat cctcatgtgt
      421 tattcggagg agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      481 ctctcttccc g
//
LOCUS       KCVO01001768             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:9637:12816
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001768
VERSION     KCVO01001768.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:9637:12816"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73797.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          155 c          128 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtactgactc agcctccctc agcgtctgag gccgccggga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagtaac agtgtgtcct ggtacctgca gctcccagaa
      241 acggctccca aactcctcat ctattataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cccgtcagcc tccctggcca tcagtgggct cgagaccgaa
      361 gatgaggctg attattactg cgcagtatgg gatgatagcc tgagcggtgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01001769             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:27826:7687
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001769
VERSION     KCVO01001769.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:27826:7687"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..390
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73798.1"
                     /translation="ECHCLLDCSGAVLF"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           97 a          151 c          126 g           92 t
ORIGIN      
        1 acatgggggg gagccagaga tcccttccaa taccagcacc atggcctgga ctctgctcct
       61 cctccagttc ctcctcactt gctgcccagg gtccaattct caggctgtag tgactcagga
      121 gccctcaatg actgtgtccc caggagggac agtcactctc acctgtggct ccagcactgg
      181 agcagtcacc agtggtaacg atccaaactg gttccagcag aaacctggac aagtccccag
      241 gggactgatt aacaatacaa acagcaaaca ctcctggacc cctgcccggg tctcaggccc
      301 cctcgcaggg ggcaaaggtg ccctgacact gtcaggtgca cagcccgagg acgagactga
      361 gtgtcattgt ctgttggact gtagtggtgc cgtgttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001770             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:14161:11086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001770
VERSION     KCVO01001770.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:14161:11086"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73799.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       386..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           82 a          140 c          141 g           98 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactgcacag actctgtggt ctcctttgaa ttgactcagc
      121 cacgctcagt gtccgtgtcc ccagggcaga cggccaggat cacctgtggg ggagacacta
      181 ttggaagtag aagtgtgcag tggtaccagc agaagccacc gcaggccctt ctgctggtca
      241 tgtatgctga tagcgaacgg ccctcaggga tccctgagcg attctctggc tccaatttag
      301 gggacaccgc caccctgacc atcagcggcg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatgtgt tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001771             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:17904:19315
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001771
VERSION     KCVO01001771.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:17904:19315"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73800.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           96 a          160 c          120 g          107 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaactaat agtgtatcct ggtaccagca gctcccagaa
      241 acggctccca aactcctcat ctattataat gatcgacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gataacagcc tgagcggtta catcttcgat
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCVO01001772             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:21662:12783
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001772
VERSION     KCVO01001772.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:21662:12783"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73801.1"
                     /translation="DYYCSSTDTSGNHVF"
     J_segment       390..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           92 a          144 c          126 g           99 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccagaaaa atatgcttat tggttccagc agaagccagg ccagtcccct gtgctgatca
      241 tcaatgagga cagcaaacgg ccctctggga tccctgagag attctctggc tccagctcag
      301 ggacagtggc caccttgact ctcagtgggg cccaggtgga ggatgaaggt gactactact
      361 gttcctcaac agataccagt ggtaatcatg tattcggcgg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001773             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:20661:20139
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001773
VERSION     KCVO01001773.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:20661:20139"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73802.1"
                     /translation="DYYCGAWDSSLSVRLF"
     J_segment       412..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          154 c          130 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggaccccgg gcagagggtc accatctcgt
      181 gcactgggag cacctccaac attggaggtt atcttgtata ctggtaccag cagttcccag
      241 gaacagcccc caaactcgtc atctatgaca ataataagcg aatttcaggg atttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagcctg
      361 gggatgaggc tgattattac tgcggagcat gggatagcag cctgagtgtt cgcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001774             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:22472:6367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001774
VERSION     KCVO01001774.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:22472:6367"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73803.1"
                     /translation="DYYCSSTDSRDNYRVF"
     J_segment       376..411
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           94 a          138 c          120 g           97 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag gcaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacgt
      301 tgactatcag tggggcccag gaggaggatg aagctgacta ctactgttcc tcaacagata
      361 gcagggataa ttatagggta ttcggcggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001775             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:12228:12382
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001775
VERSION     KCVO01001775.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12228:12382"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..445
                     /note="immunoglobulin light chain variable region"
     V_region        112..445
     V_segment       112..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73804.1"
                     /translation="DYYCSLWDSRLSSRVF"
     J_segment       410..445
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           92 a          155 c          127 g          109 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc tccttctcac tctgctggtt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagc atctggggcc cccgggcaga gggtcaccat ctcctgcact
      181 gggaccagct ccaacatcgg ggcgaattat tatgtttcct ggtaccagca gttcccagga
      241 acagccccca aactcctcat ctatgaaaat aataagcgac cctcaggggt ttctgaccga
      301 ttctctggct ccaagtctgg tacctcagcc tccctgacca tctctggact ccaatctgag
      361 gatgaggctg attattactg ctcactatgg gatagcaggc tgagtagtcg ggtattcggc
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01001776             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:27424:9297
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001776
VERSION     KCVO01001776.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:27424:9297"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73805.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           82 a          162 c          120 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac gggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc ctttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa caccacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac ttccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001777             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:4868:7847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001777
VERSION     KCVO01001777.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:4868:7847"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73806.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       412..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          158 c          130 g          108 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggaccccgg gcagagggtc accatctcgt
      181 gcactgggag cagctccaac attggaggtt atcttgtata ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctatgaca ataataagcg accctcaggg atttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagcctg
      361 gggatgaggc tgattattac tgcggtgcat gggatagcag cctgagtgct cgcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001778             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:12475:15081
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001778
VERSION     KCVO01001778.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:12475:15081"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..425
                     /note="immunoglobulin light chain variable region"
     V_region        105..425
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73807.1"
                     /translation="DYYCQVWDSSSAVLF"
     J_segment       389..425
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>464
                     /gene="IGLC"
BASE COUNT           88 a          140 c          137 g           99 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gagttgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggataca
      181 tcattggaag taaaagtgtg cagtggtacc agcagaagtc accgcaggcc cttgtgctgg
      241 tcatctatgc tgataacaaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggatcac cgccaccctg accatcagcg gggtcgaggc cggggatgag gcagactatt
      361 actgtcaggt gtgggacagt agtagtgctg tgttattcgg aggagggacc cggctgaccg
      421 tcctaagtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001779             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:24789:2780
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001779
VERSION     KCVO01001779.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:24789:2780"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73808.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       402..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           86 a          155 c          124 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatct tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacacaag cagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001780             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:15918:6952
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001780
VERSION     KCVO01001780.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:15918:6952"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..425
                     /note="immunoglobulin light chain variable region"
     V_region        102..425
     V_segment       102..397
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <360..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73809.1"
                     /translation="DYFCCSYADTYTFVF"
     J_segment       402..425
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>470
                     /gene="IGLC"
BASE COUNT           83 a          156 c          119 g          112 t
ORIGIN      
        1 acatgggggg tctcagacgg cagcgctctc gggacatctc caccatggcc tgggctctgc
       61 tcctcctcac cctcctcact cagggcacag gatcctgggc tcaggctgcc ctgactcagc
      121 ctcgctcagt gtctgggtct cctggacagt cggtcaccat ctcctgcact ggaaccagca
      181 gtgacatcgg tggttataac tttgtctcct ggtaccaaca acatccaggc acagccccca
      241 aactcatgat ttatgaggtc aatcagcggc cctcaggggt ctctgatcgc ttctctggct
      301 caaagtctgg caacacggcc tccctgaccg tctccggggt ccaggctgag gacgaggctg
      361 attatttctg ctgctcatat gcagacacct acacttttgt tttcggaagt ggcaccaggt
      421 tgaccgtcgt cggtcagccc aaggcttccc ccttggtcac tctgttcccg
//
LOCUS       KCVO01001781             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:14650:12547
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001781
VERSION     KCVO01001781.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:14650:12547"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..450
                     /note="immunoglobulin light chain variable region"
     V_region        117..450
     V_segment       117..408
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73810.1"
                     /translation="DYFCSVWDSSLTIYIF"
     J_segment       413..450
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           90 a          158 c          127 g          113 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctctcctt ctcactctgc tggttcactg cacagggtcc ggggcccagc
      121 ctgtgctgac gcagccgccc tcagcatctg gggcccccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac atcggggcgg gttattctgt atcctggtat cagcagttcc
      241 caggaacagc ccccaaactc ctcatctatg aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtacct cagcctccct gactatcact ggactccaat
      361 ctgaggatga ggctgattat ttctgctctg tctgggatag cagcctgact atttacatct
      421 tcggtgctgg gacccggctc accgtcctag gtcagcccaa ggcttccccc acggtcactc
      481 tgttcccg
//
LOCUS       KCVO01001782             362 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:14703:5439
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001782
VERSION     KCVO01001782.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 362)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:14703:5439"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    122..324
                     /note="immunoglobulin light chain variable region"
     V_region        122..324
     V_segment       122..285
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <249..>296
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73811.1"
                     /translation="DYYCYSMDSSTYLGFF"
     J_segment       287..324
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        325..>362
                     /gene="IGLC"
BASE COUNT           66 a          117 c           92 g           87 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtcccctgt attgatcatc tatgaggaca ccaaacggcc ctctgggatc cctgagagat
      181 tctctggctc cagctcaggg acagtggcca ccttgactat cagtggggcc caggtggagg
      241 atgaagctga ctactactgt tactcaatgg atagcagtac ttatcttggc ttcttcggag
      301 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      361 cg
//
LOCUS       KCVO01001783             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:6496:17193
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001783
VERSION     KCVO01001783.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:6496:17193"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73812.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           92 a          141 c          126 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtccccag tgctgatcat
      241 caatgaggac agcaaacggc cctctgggat tcctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagtagtg gtaattatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001784             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:21987:2761
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001784
VERSION     KCVO01001784.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:21987:2761"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73813.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       389..423
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           91 a          142 c          126 g          102 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 caaaaaagta tgtttattgg ttccagcaga agccaggcca gtcccctgtg ctgatcatct
      241 atgaggacag cagacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc agtggggccc agggggagga tgaagctgac tactactgtt
      361 attcaatgga tagcagtggt actcagagca tcttcggtgc tgggacccgg ctcaccgtcc
      421 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCVO01001785             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:25856:15363
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001785
VERSION     KCVO01001785.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:25856:15363"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73814.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       402..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           87 a          156 c          123 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccaga ctgaggacga
      361 ggctgattat tactgcagct catacacaag cagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001786             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:10748:15024
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001786
VERSION     KCVO01001786.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:10748:15024"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73815.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          159 c          121 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaactaat agtgtatcct ggtaccagca gctcccagaa
      241 acggctccca aactcctcat ctattataat gatcgacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gataacagcc tgagtggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCVO01001787             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:2724:16180
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001787
VERSION     KCVO01001787.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:2724:16180"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..392
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73816.1"
                     /translation="DYYCFVYYSGTQFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           99 a          152 c          114 g          100 t
ORIGIN      
        1 acatgggggg agccagagat cccttccaat accagcacca tggcctggac tctcctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtggctc cagcactgga
      181 gcagtcacca gtggtaactt tccaaactgg ttccagcaga aacctggaca agtccccagg
      241 ggactgattt ataatacaaa caacaaacac tcctggaccc ctgcccggtt ctcaggctcc
      301 ctcgctgggg gcaaagctgc cctgacactg tcaggagcac agcccgagga cgaggctgat
      361 tattactgtt tcgtgtacta tagtggtact caattcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001788             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:9000:14355
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001788
VERSION     KCVO01001788.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:9000:14355"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73817.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           93 a          154 c          128 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagtaac agtgtgtcct ggtacctgca gctcccagaa
      241 acggctccca aactcctcat ctattataat gataggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cccgtcagcc tccctggcca tcagtgggct cgagaccgaa
      361 gatgaggctg attattactg cgcagtatgg gatgatagcc tgagcggtgt gttattcgga
      421 ggagggaccc gactgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01001789             443 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:20096:19992
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001789
VERSION     KCVO01001789.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 443)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:20096:19992"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..405
                     /note="immunoglobulin light chain variable region"
     V_region        87..405
     V_segment       87..369
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>377
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73818.1"
                     /translation="DYYCYSEDSRSSIF"
     J_segment       371..405
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        406..>443
                     /gene="IGLC"
BASE COUNT           92 a          140 c          115 g           96 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggta ccagcagaaa ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagaggaca
      361 gcaggagtag catcttcggt gctgggaccc ggctcaccgt cctaggtcag cccaaggctt
      421 cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001790             304 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:4836:13126
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001790
VERSION     KCVO01001790.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 304)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:4836:13126"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..264
                     /note="immunoglobulin light chain variable region"
     V_region        8..264
     V_segment       8..229
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <191..>238
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73819.1"
                     /translation="DYYCQVWDFSGDHNIF"
     J_segment       231..264
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        265..>304
                     /gene="IGLC"
BASE COUNT           64 a           91 c           87 g           62 t
ORIGIN      
        1 acatgggggg agagacaaca ttggaaataa aaatgtgcac tggtaccagc agcggccacc
       61 gcgggcccct gtactggtca tctattatga taccgagcgg ccctcaggga tccctgagcg
      121 attctctggc tccacatcag ggaacaccgc caccctgacc atcagcgggg tcgaggccgg
      181 ggatgaggct gactattact gtcaggtgtg ggactttagt ggtgatcata acatcttcga
      241 tgctgggacc cggctcaccg tcctcggtca gcccaaggct tcccccacgg tcactctgtt
      301 cccg
//
LOCUS       KCVO01001791             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:14401:5347
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001791
VERSION     KCVO01001791.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:14401:5347"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..381
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73820.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       385..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           96 a          144 c          122 g           97 t
ORIGIN      
        1 acatggggtg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactcccca tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcgttgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agatgcattg
      181 ccagaaaaat atgcttattg gtaccagcag aaaccaggcc agtcccctat gctgatcatc
      241 tgtgaggaca gcaaacggcc ctctgggatc cctgaaagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cactggggcc caggtggagg atgaagctga ctactactgt
      361 tactcagcag acaacagtgg tcagggctca ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001792             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:11123:7259
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001792
VERSION     KCVO01001792.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:11123:7259"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73821.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           90 a          140 c          117 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatcaat gaggacagca
      241 aacggccctc tgggatccct ggaagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gtagtggtaa ttatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001793             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:3425:17158
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001793
VERSION     KCVO01001793.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:3425:17158"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73822.1"
                     /translation="DYYCAAWDDSLNSPFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          156 c          114 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaac
      181 attggaagta attatgtaaa ctggtaccag caactcccag gaacggcccc caaactcctc
      241 atctatttta ctaatcagcg accctcaggg gtccctgacc gattctctgg ctctacgtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcggcat gggatgacag cctgaacagt cccttcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001794             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:14484:7419
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001794
VERSION     KCVO01001794.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:14484:7419"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73823.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       397..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          141 c          139 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagactctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaaacc agcgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga gcgattcttt ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgtgtatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001795             374 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:18107:17910
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001795
VERSION     KCVO01001795.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 374)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:18107:17910"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    179..336
                     /note="immunoglobulin light chain variable region"
     V_region        179..336
     V_segment       179..300
                     /gene="IGLV4-8"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <258..>308
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73824.1"
                     /translation="DYYCGECHTIDGQYDLF"
     J_segment       306..336
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        337..>374
                     /gene="IGLC"
BASE COUNT           57 a          133 c           95 g           89 t
ORIGIN      
        1 acatgggggg ccactgggca gcctcgagca gagctcctgg aagtccctcc aaccatggcc
       61 tgggtctcct tctacctcct gcccttcatt ttctccacag gtctctgtgc tctgcctgtg
      121 ctgactcagc ccccgtctgc atctgcctcg ttgggagcct ctgtcaagct cacctgcacc
      181 ctgatcgctt cttgggctcc agctctgggg ctgaccgcta cctcaccatc tccaacctcc
      241 agtctgacga cgaggctgac tattactgtg gagagtgcca cacgattgat ggccagtacg
      301 atttgttcgg aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg
      361 tcactctctt cccg
//
LOCUS       KCVO01001796             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:19794:17395
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001796
VERSION     KCVO01001796.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19794:17395"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    73..289
                     /note="immunoglobulin light chain variable region"
     V_region        73..289
     V_segment       73..252
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <214..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73825.1"
                     /translation="DYFCYSTTSSGNHRLF"
     J_segment       255..289
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>327
                     /gene="IGLC"
BASE COUNT           65 a          101 c           87 g           74 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacagaagac aggccagtcc cctgtgctga tcatctatga ggacagcaaa
      121 cggccctctg ggatccctga gagattctct ggctccagct cagggacagt ggccaccttg
      181 actatcagtg gggcccaggt ggaagatgaa gctgactact tctgttactc aacgactagc
      241 agtggtaatc ataggttatt cggaggaggg acccgggtga ccgtcctagg tcagcccaag
      301 gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001797             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:23738:12384
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001797
VERSION     KCVO01001797.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:23738:12384"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73826.1"
                     /translation="DYYCGVWDSSLSARLF"
     J_segment       412..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          156 c          129 g          109 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggaccccgg gcagagggtc accatctcgt
      181 gcactgggag cagctccaac attggaggtt attttgtata ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctatgaca ataataaacg accctcaggg atttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagcctg
      361 gggatgaggc tgattattac tgcggagtat gggatagcag cctgagtgct cgcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001798             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:24888:7895
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001798
VERSION     KCVO01001798.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:24888:7895"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73827.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       390..424
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           92 a          142 c          125 g          103 t
ORIGIN      
        1 acatgggggg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactccccc tcctcacttt ctgcacagtc tctgcagcct cctatgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctttgg agatgcattg
      181 ccaaaaaagt atgcttattg gttccagcag aagccaggcc agtcccctgt actgttcatc
      241 tatgaggaca gcaaacggcc ctctgggatc cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cagtggggcc cagggggagg atgaagctga ctactactgt
      361 tattcaatgg atagcagtgg tacgcagagc atcttcggtg ctgggacccg gctcaccgtc
      421 ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01001799             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:19217:12186
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001799
VERSION     KCVO01001799.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19217:12186"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73828.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          161 c          124 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001800             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:15329:4772
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001800
VERSION     KCVO01001800.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15329:4772"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..448
                     /note="immunoglobulin light chain variable region"
     V_region        115..448
     V_segment       115..408
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73829.1"
                     /translation="DYYCSLWDSRLSSRVF"
     J_segment       413..448
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           94 a          156 c          127 g          109 t
ORIGIN      
        1 acatgggaag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctctccttct cactctgctg gttcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agcatctggg gcccccgggc agagggtcac catctcctgc
      181 actgggacca gctccaacat cggggcgaat tattatgttt cctggtacca gcagttccca
      241 ggaacagccc ccaaactcct catctatgaa aataataagc gaccctcagg ggtttctgac
      301 cgattctctg gctccaagtc tggtacctca gcctccctga ccatctctgg actccaatct
      361 gaggatgagg ctgattatta ctgctcacta tgggatagca ggctgagtag tcgggtattc
      421 ggcggaggga cccgactgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01001801             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:21106:5041
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001801
VERSION     KCVO01001801.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:21106:5041"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..446
                     /note="immunoglobulin light chain variable region"
     V_region        117..446
     V_segment       117..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73830.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       411..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>485
                     /gene="IGLC"
BASE COUNT           90 a          156 c          128 g          111 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatgtcct
      181 gcactgggag cagctccaac attggaggtt attatgtgca gtggtacctg caacttccag
      241 gaacggcccc caaacttctc atctatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggtacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cctgagtgcc gtgttattcg
      421 gaggagggac ccggctgacc gtcctaagtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001802             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:19270:9444
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001802
VERSION     KCVO01001802.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:19270:9444"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73831.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       397..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          142 c          140 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagtctctgt ggtctcccat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaagcc agcgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgtgtatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001803             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:7229:16164
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001803
VERSION     KCVO01001803.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:7229:16164"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..412
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73832.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       414..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           91 a          157 c          130 g          110 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cgggcagagg gtcaccatct
      181 cctgcactgg gagcagttcc aacattggag gttattatgt gcagtggtac cagcagcttc
      241 caggaacggc ccccaaactc ctcatgtatg aaaataataa gcgaccctca ggggtttctg
      301 atcgattctc tggctcccag tctggtacct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagcctgagt gccgtgttat
      421 tcggagcagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCVO01001804             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:4660:7261
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001804
VERSION     KCVO01001804.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:4660:7261"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..431
                     /note="immunoglobulin light chain variable region"
     V_region        101..431
     V_segment       101..394
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73833.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       395..431
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           88 a          151 c          126 g          104 t
ORIGIN      
        1 acatgggggg gtacagaagg caggactcag gacaatctcc agcatggcct ggttccctct
       61 cctcctcacc ctcctcactc actgtgcagg gtcctgggcc cagtctgtgc tgactcagcc
      121 tccctcagcg tctgaggccg ccgggaagag tgtcaccatc tcctgttctg gaagcacctc
      181 caacatcgga agtaacagtg tgtcctggta cctgcagctc ccagaaacgg ctcccaaact
      241 cctcatctat tataatgatc ggcgagcctc aggtgtctct gaccgattct ctggctccaa
      301 gtctggcccg tcagcctccc tggccatcag tgggctcgag accgaagatg aggctgatta
      361 ttactgcgca gtatgggatg atagcctgag cggtgtgttg ttcggaggag ggacccgact
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001805             315 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:13551:5656
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001805
VERSION     KCVO01001805.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 315)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:13551:5656"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..277
                     /note="immunoglobulin light chain variable region"
     V_region        8..277
     V_segment       8..240
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <202..>249
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73834.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       245..277
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        278..>315
                     /gene="IGLC"
BASE COUNT           68 a           84 c           98 g           65 t
ORIGIN      
        1 acatggggga tcacctgtgg gggagacaat gttggaagtg aatatgtgca ctggtaccaa
       61 cagaaaccag cgcaggcccc tgtggtggtc atccattata atagtgaccg gccctcaggg
      121 atccctgagc gattctctgg ctccaaatca gggaacaccg ccaccctgac catcagcggg
      181 gtcgaggccg gggatgaggc tgactattac tgtcaggtgt gggacagtag tagtgatcat
      241 tgtgtattgg gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg
      301 gtcactctct tcccg
//
LOCUS       KCVO01001806             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:25179:6796
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001806
VERSION     KCVO01001806.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:25179:6796"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73835.1"
                     /translation="DYYCQSSDSSLTAVLF"
     J_segment       414..450
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           89 a          161 c          127 g          111 t
ORIGIN      
        1 acatggggga agctctgctt cgtctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctc gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacacagccg ccctcagtgt ctggggcccc agggcagagg gtcaccatct
      181 cctgcactgg gagaggctcc aacattggag gtcattatgt ttactggtac cagcagctcc
      241 caggattggc ccccaaactc ctcatctatg acaataatga gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtacct cagcctccct gaccatcact gggctccaga
      361 ctgaggatga ggctgattat tactgccagt cctctgacag cagcctgact gctgtgttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCVO01001807             526 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:18082:9955
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001807
VERSION     KCVO01001807.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 526)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 526)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18082:9955"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    158..488
                     /note="immunoglobulin light chain variable region"
     V_region        158..488
     V_segment       158..451
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <413..>460
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73836.1"
                     /translation="DYYCGAWDSSLSTRLF"
     J_segment       453..488
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        489..>526
                     /gene="IGLC"
BASE COUNT          102 a          168 c          136 g          120 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacagaa gcagaatcat
      121 gattcctgtg tctcttccac ttccagggtc ctgggcccag tctgtgctga cgcagccgcc
      181 ctcagtgtct ggggaccccg ggcagagggt caccatctcg tgcactggga gcagctccaa
      241 cattggaggt tattttgtat actggtacca gcagttccca ggaacagccc ccaaactcct
      301 catctatgac aataataagc gaccctcagg gatttctgac cgattctctg gctccaagtc
      361 tggtacctca gcctccctga ccatcactgg gctccagcct ggggatgagg ctgattatta
      421 ctgcggagca tgggatagca gcctgagtac tcgcttattc ggaggaggga cccggctgac
      481 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001808             289 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:7341:18840
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001808
VERSION     KCVO01001808.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 289)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:7341:18840"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..251
                     /note="immunoglobulin light chain variable region"
     V_region        8..251
     V_segment       8..214
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <176..>223
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73837.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       218..251
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        252..>289
                     /gene="IGLC"
BASE COUNT           62 a           81 c           86 g           60 t
ORIGIN      
        1 acatggggga agtgaatatg tccactggta tcaacagaaa ccaccgcagg cccctgtggt
       61 ggtcatctat tataatactg accggccctc ggggatccct gagcgattct ctggctccaa
      121 atcagggaac accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta
      181 ttactgtcag gtgtgggaca gtaggagtga tcatagttta ttgggaggag ggacccggct
      241 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001809             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:11962:17537
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001809
VERSION     KCVO01001809.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:11962:17537"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..441
                     /note="immunoglobulin light chain variable region"
     V_region        112..441
     V_segment       112..404
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73838.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       406..441
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        442..>480
                     /gene="IGLC"
BASE COUNT           91 a          154 c          127 g          108 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcagt gtctggggcg cccgggcaga gggtcaccat ctcctgcact
      181 gggagcagct ccaacattgg aggttattat gtgcagtggt accagcaact tccaggaacg
      241 gcccccaaag ttctcatcta tgaaaataat aagcgaccct caggggtttc tgatcgattc
      301 tctggctccc agtctggtac ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgcca gtcctatgac agcagcctga gtgccgtgtt attcggagga
      421 gggacccggc tgaccgtcct aagtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001810             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:10938:14557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001810
VERSION     KCVO01001810.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:10938:14557"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73839.1"
                     /translation="DYYCAAWDDSLNSPFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          155 c          113 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcaaccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaac
      181 attggaagta attatgtaaa ctggtaccag caactcccag gaacggcccc caaactcctc
      241 atctatttta ctaatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcggcat gggatgacag cctgaacagt cccttcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001811             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:14832:18289
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001811
VERSION     KCVO01001811.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14832:18289"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73840.1"
                     /translation="DYHCQVWDSSSDVLF"
     J_segment       386..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           86 a          142 c          139 g           94 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactgcacag actctgtggt ctcctatgaa ttgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacagta
      181 ttggaagtag aagcgtgcag tggtaccagc agaagccacc gcaggccctt gcactggtca
      241 tctatgctga tagcgaacgg ccctcaggga tccctgagcg attctctggc tccaatctag
      301 ggaacaccgc caccctgacc attagcggcg tcgaggccgg ggatgaggct gactatcact
      361 gtcaggtgtg ggacagtagt agtgatgtgt tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001812             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:10735:14395
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001812
VERSION     KCVO01001812.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10735:14395"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73841.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           89 a          142 c          137 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag aatcacctgt gggggagaca
      181 gcattggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttctactgg
      241 tcatctatgc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tattattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001813             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:15769:6277
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001813
VERSION     KCVO01001813.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:15769:6277"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73842.1"
                     /translation="DYYCYSTRGSGYHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          142 c          126 g          104 t
ORIGIN      
        1 acatgggggt gggcgcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ctctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtgcag gatgaagctg actactactg
      361 ttactcaact cgtggcagtg gttatcatgg cttattcgga ggagggacct ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001814             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:24692:6288
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001814
VERSION     KCVO01001814.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:24692:6288"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..412
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73843.1"
                     /translation="DYHCQSYDSSLSAWVF"
     J_segment       413..449
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           87 a          160 c          126 g          114 t
ORIGIN      
        1 acatggggaa gctctgcttc atctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctcg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acacagccgc cctcagtgtc tggggcccca gggcagaggg tcaccatctc
      181 ctgcactggg agcagttcca tcattggaga ttattttgta tactggtatc agcagttccc
      241 aggaatggcc cccaaactcc tcatctatga caataataag cggccctcag ggctttctgc
      301 ccgattctct ggctccaagt ccggtacctc tgcctccctg accatcactg ggctccagac
      361 tgaggatgag gctgattatc actgccagtc ctatgacagt agcctgagtg cttgggtgtt
      421 cggcgggggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCVO01001815             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:10658:13676
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001815
VERSION     KCVO01001815.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:10658:13676"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73844.1"
                     /translation="EYYCSSFAATYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           88 a          155 c          117 g          115 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 caacagtgac atcggtaatt ataactatgt ctcctggtac caacaacatc caggcacagc
      241 ccccaaactc atgatttatg aggtcagtga gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatttct ggactccagg ctgaggacga
      361 ggctgaatat tactgtagtt cttttgcagc cacttacact tttgtgttcg gaagtggcac
      421 caagttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001816             492 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:15076:6924
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001816
VERSION     KCVO01001816.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 492)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15076:6924"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..454
                     /note="immunoglobulin light chain variable region"
     V_region        130..454
     V_segment       130..417
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>426
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73845.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       418..454
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        455..>492
                     /gene="IGLC"
BASE COUNT          101 a          151 c          134 g          106 t
ORIGIN      
        1 acatggggaa gagaagccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactccccc tcctcacttt ctgcacaggc
      121 tctgcagcct cctctgagct gacacagcca ccctcggtgt cagtgtcccc aggacagacg
      181 gccaggatca cctgctctgg agatgcattg ccaaaatact atgcttattg gttccagcag
      241 aagccaggtc agtcccctgt ggcgatcatc tatgaggaca acaaacggcc ctctgggatc
      301 cctgagagat tctctggctc cagctcaggg acagtggcca ccttgactat cagtggggcc
      361 caggtcgagg atgaagctga ctactactgt tactcaacag atagcagtgg tactaatggc
      421 ttattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      481 actctcttcc cg
//
LOCUS       KCVO01001817             494 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:18481:4031
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001817
VERSION     KCVO01001817.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 494)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:18481:4031"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..456
                     /note="immunoglobulin light chain variable region"
     V_region        123..456
     V_segment       123..416
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73846.1"
                     /translation="DYYCLSSDSSLSAHYIF"
     J_segment       419..456
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>494
                     /gene="IGLC"
BASE COUNT           95 a          167 c          123 g          109 t
ORIGIN      
        1 acatgggggg ggaagctctg cttcagctgt gggcacagga ggcagcactc aggacagtct
       61 ccagcatggc ctcgtctcct ctcctcctca cccttctcat tcactgcaca gggtcctggg
      121 cccagtctgt gctgacacag ccaccctcag tgtctggggc cccagggcag agggtcacca
      181 tctcgtgcac tgggagcagc tccagcattg gaggtgatta tgtatcctgg taccaacagc
      241 tcccaggaac gacccccaaa ctcctcatct atcaaaataa taagcgaccc tcaggggttt
      301 ctgaccgatt ctctggctcc aagtctggta cctcagcctc cctgaccatc actgggctcc
      361 agactgagga tgaggctgat tactactgcc tgtcctctga cagcagcctg agtgctcatt
      421 acatcttcgg tcctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg
      481 tcactctgtt cccg
//
LOCUS       KCVO01001818             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:14622:8359
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001818
VERSION     KCVO01001818.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:14622:8359"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..449
                     /note="immunoglobulin light chain variable region"
     V_region        120..449
     V_segment       120..412
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73847.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       414..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>488
                     /gene="IGLC"
BASE COUNT           92 a          158 c          127 g          111 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggcgcc cggccagagg gtcaccatct
      181 cctgcactgg gagcagctcc aacattggag gttattatgt ccagtggtac cagcaacttc
      241 caggaacggc ccccaaagtt ctcatctatg aaaataataa gcgaccctca ggggtttctg
      301 atcgattctc tggctcccag tctggttcct cagcctccct gaccatcact ggactccagt
      361 ctgaggatga ggctgattat tactgccagt cctatgacag cagcctgagt gccgtgttat
      421 tcggaggagg gacccggctg accgtcctaa gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCVO01001819             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:11680:9974
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001819
VERSION     KCVO01001819.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11680:9974"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73848.1"
                     /translation="DYYCSSTDTSGNHVF"
     J_segment       388..421
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           91 a          143 c          123 g          102 t
ORIGIN      
        1 acatggggtg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactccccc tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agatgcattg
      181 ccagaaaaat ttgcttattg gttccagcag aagtcaggcc agtcccctgt gttgatcatc
      241 aatgaggaca gcaaacggcc ctctgggatc cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactct cagtggggcc caggtggagg atgaagctga ctactactgt
      361 tcctcaacag ataccagtgg taatcatgta ttcggcggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001820             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:10812:17455
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001820
VERSION     KCVO01001820.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10812:17455"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73849.1"
                     /translation="DYYCYSTDSSGNHIF"
     J_segment       389..423
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           95 a          145 c          119 g          102 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccaaaaaa atatgcttat tggttccagc agaagccagg ccagtcccct gtgctgatca
      241 tctatgacga cagtaaacgg ccctctggga tccctgagag attctctggc tccagctcag
      301 ggacagtggc caccttgact atcagtgggg cccaggtgga ggatgaagct gactactact
      361 gttactcaac agatagcagt ggtaatcaca tcttcgctac tgggacccgg ctcaccgtcc
      421 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCVO01001821             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:11406:16919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001821
VERSION     KCVO01001821.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11406:16919"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73850.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           88 a          161 c          125 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcggaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atatactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001822             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:12172:15807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001822
VERSION     KCVO01001822.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:12172:15807"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..427
                     /note="immunoglobulin light chain variable region"
     V_region        105..427
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73851.1"
                     /translation="DYYCQVWDSSSDHWVF"
     J_segment       392..427
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>467
                     /gene="IGLC"
BASE COUNT           84 a          143 c          143 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgc ggtctcctat gagctgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggcccg ggtcacctgt gggggagaca
      181 acattggaag taaaagtgtg cagtggttcc agcagaagcc accgcaggcc cctgtgttgg
      241 tcatttatgg tgatagcgaa cggccctcag ggatccctga gcgattctct ggttccaact
      301 cagggaacat tgccaccctg accatcagcg gggtcgaggc cgggaatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgggtatt cggcggaggg acccggctga
      421 ccgtcctcgg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001823             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:8997:9893
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001823
VERSION     KCVO01001823.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:8997:9893"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    86..416
                     /note="immunoglobulin light chain variable region"
     V_region        86..416
     V_segment       86..379
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73852.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       381..416
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           83 a          150 c          119 g          102 t
ORIGIN      
        1 acatggggga ctcaggacag tctccagcat ggcctggtct cctctcctcc tcacccttct
       61 cattcactgc acagggtcct gggcccagtc tgtgctgacg cagccgccct cagtgtctgg
      121 ggaccccggg cagaaggtca ccatctcgtg cactgggagc agctccaaca ttggaggtta
      181 ttttgtgtac tggtaccagc agttcccagg aacagccccc caactcctca tctatgacaa
      241 taataagcga ccctcaggga tttctgaccg attctctggc tccaagtctg gtacctcagc
      301 ctccctgacc atcactgggc tccagcctgg ggatgaggct gattattact gcggcgcatg
      361 ggatagcagc ctgagtgctc gcttattcgg aggagggacc cggctgaccg tcctaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001824             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:22651:16666
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001824
VERSION     KCVO01001824.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:22651:16666"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73853.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          142 c          138 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgag ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaatg
      181 ttggagatga atttgtgcac tggtaccaac agaagccacc gcaggcccct gtggtggtca
      241 tccattataa tagtgaccgg ccctcaggga tccctgagcg attctctgcc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatcata gtttattggg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001825             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:14143:20083
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001825
VERSION     KCVO01001825.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14143:20083"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73854.1"
                     /translation="DYYCYSSDGSADYWVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           89 a          138 c          130 g          106 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac agcaaacggc gttctgggat ccctgagaga ttctctggtt ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcatca gatggtagtg ctgattattg ggtgttcggc ggagggaccc ggctgaccgt
      421 cccgggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001826             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:18584:12713
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001826
VERSION     KCVO01001826.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18584:12713"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73855.1"
                     /translation="DYYCYSTDNSGDHRGFF"
     J_segment       384..414
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           87 a          145 c          117 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct ctgagctgac acagcccccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tacattgcca aaaaaatttg
      181 cttcttggtt ccttcagaag ccaggccagt cccctgtgct gatcatctat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ttcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagata
      361 acagtggtga tcataggggc ttcttcggcg gggggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001827             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:12904:4646
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001827
VERSION     KCVO01001827.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12904:4646"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..429
                     /note="immunoglobulin light chain variable region"
     V_region        101..429
     V_segment       101..395
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73856.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       396..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>469
                     /gene="IGLC"
BASE COUNT           86 a          155 c          120 g          108 t
ORIGIN      
        1 acatggggat ctcaggaggc agcactctca ggacgtctcc accatggcct gggctctgct
       61 cctcctcacc ctcctcactc agggcacagg atcctgggct caggctgccc tgactcagtc
      121 tccctctgtg tctgggtctc ctggacagtc ggtcaccatt tcctgcactg gaaccagcag
      181 tgacattggt gattataacc gtgtctcctg gtaccaacag cacccaggca aagcccccaa
      241 actcatgatt tatgaggtca gtgatcggcc ctcaggggtc tctgatcgct tctctggttc
      301 caagtctggc aacacggcct ccctgatcat ctctgggctc caggctgagg acgaggctga
      361 ttattactgc agctcataca caagcagtag cacttgggta ttcggcggag ggacccggct
      421 gaccgtcctt ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001828             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:7325:15064
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001828
VERSION     KCVO01001828.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7325:15064"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..390
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73857.1"
                     /translation="ECHCLLDCSGAVLL"
     J_segment       392..428
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           98 a          150 c          126 g           92 t
ORIGIN      
        1 acatgggggg gagccagaga tcccttccaa taccagcacc atggcctgga ctctgctcct
       61 cctccagttc ctcctcactt gctgcccagg gtccaattct caggctgtag tgactcagga
      121 gccctcaatg actgtgtccc caggagggac agtcactctc acctgtggct ccagcactgg
      181 agcagtcacc agtggtaacg atccaaactg gttccagcag aaacctggac aagtccccag
      241 gggactgatt aacaatacaa acagcaaaca ctcctggacc cctgcccggg tctcaggccc
      301 cctcgcaggg ggcaaaggtg ccctgacact gtcaggtgca cagcccgagg acgagactga
      361 gtgtcattgt ctgttggact gtagtggtgc cgtgttatta ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001829             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:24739:10812
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001829
VERSION     KCVO01001829.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:24739:10812"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73858.1"
                     /translation="DYYCQVWDSSSDHRVF"
     J_segment       389..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           87 a          144 c          139 g           92 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctta ctgcacaggc tctgcggtct cctatgagct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaacctt
      181 ggaagtaaat atgtgcactg gtaccaacag aagccaacgc aggcccctgt ggtggtcatc
      241 tattatgata gtgaccggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtagtag tgatcatcgg gtattcggcg gagggacccg gctgaccgcc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001830             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:10616:10941
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001830
VERSION     KCVO01001830.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:10616:10941"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73859.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           92 a          142 c          125 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tttgcttatt ggttccaaca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaaggtg actactactg
      361 ttcctcaaca gatagcagtg gtaattatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001831             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:8302:13464
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001831
VERSION     KCVO01001831.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:8302:13464"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..419
                     /note="immunoglobulin light chain variable region"
     V_region        104..419
     V_segment       104..385
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73860.1"
                     /translation="DYYCQSTDSSGFIF"
     J_segment       388..419
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>460
                     /gene="IGLC"
BASE COUNT          101 a          139 c          119 g          101 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 accaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aactatggtc agtggttcca gcagaagcca ggccaggccc ctgtgctgct
      241 gatatttaaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacatca attaccttga ccatcagtgg ggcccatgca gaagatgagg ctgactacta
      361 ctgtcaatca acagacagca gtggtttcat cttcggtgct gggacccggc tcaccgtccc
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01001832             451 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:15418:15251
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001832
VERSION     KCVO01001832.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 451)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:15418:15251"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    83..413
                     /note="immunoglobulin light chain variable region"
     V_region        83..413
     V_segment       83..377
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <341..>385
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73861.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       378..413
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        414..>451
                     /gene="IGLC"
BASE COUNT           82 a          153 c          112 g          104 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctca ctcaggctgc cctgactcag tctccctctg tgtctgggtc
      121 tcctggacag tcggtcacca tttcctgcac tggaaccagc agtgacattg gtggttataa
      181 ccgtgtctcc tggtaccaac agcacccagg caaagccccc aaactcatga tttatgacgt
      241 cagtgatcgg ccctcagggg tctctgatcg cttctctggt tccaagtctg gcaacacggc
      301 ctccctgatc atctctgggc tccaggctga ggacgaggct gattattact gcagctcata
      361 cacaagcact accacttggc tattcggcgg agggacccgc ctgaccgtcc taggtcagcc
      421 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001833             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:22504:4433
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001833
VERSION     KCVO01001833.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22504:4433"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73862.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           87 a          154 c          124 g          108 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagtaccca ggcaaagccc
      241 ccaaagtcat catttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttcactg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca gtagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001834             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:13150:4132
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001834
VERSION     KCVO01001834.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13150:4132"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73863.1"
                     /translation="DYYCYSSDTSADYWVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>449
                     /gene="IGLC"
BASE COUNT           88 a          140 c          118 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggttccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcatcagata
      361 ccagtgctga ttattgggtg ttcggcggag ggacccggct gaccgtccca ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001835             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:14013:18363
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001835
VERSION     KCVO01001835.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14013:18363"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..368
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73864.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           95 a          143 c          112 g           96 t
ORIGIN      
        1 tcagcaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggta ccagcagaaa ccaggccagt cccctatgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gaaagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcac tggggcccag gtggaggatg aatctgacta ctactgttac tcagcagaca
      361 acagtggtca gggctcattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001836             280 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:11569:14559
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001836
VERSION     KCVO01001836.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 280)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 280)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:11569:14559"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..242
                     /note="immunoglobulin light chain variable region"
     V_region        7..242
     V_segment       7..203
                     /gene="IGLV10-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <167..>214
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73865.1"
                     /translation="DYYCSAWDSSLSGVLF"
     J_segment       205..242
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        243..>280
                     /gene="IGLC"
BASE COUNT           61 a           92 c           76 g           51 t
ORIGIN      
        1 acatggggga gcaacttggc tgcagcagca ccagggccac cctcccaaac tgctgtccta
       61 caggaataac aaccggccct cggggatctc agagagattc tctgcatcca ggtcaggaaa
      121 cacagcctcc ctgaccgtca ccggactcca acctgaggat gaggctgact attactgctc
      181 agcatgggac agcagcctca gtggtgtgtt attcggagga gggacccggc tgaccgtcct
      241 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001837             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:23544:4852
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001837
VERSION     KCVO01001837.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:23544:4852"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73866.1"
                     /translation="DYYCSSTDTSGNHVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           89 a          141 c          116 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatttg
      181 cttattggtt ccagcagaag tcaggccagt cccctgtgtt gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 ccagtggtaa tcatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001838             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:8604:8136
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001838
VERSION     KCVO01001838.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:8604:8136"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73867.1"
                     /translation="DYYCQVWDSSTDHTLL"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          142 c          138 g           96 t
ORIGIN      
        1 acatgggggt ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgag ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaatg
      181 ttggaagtga atatgtgcac tggtaccaac agaagccacc gcaggcccct gtggtggtca
      241 tccattataa tagtgaccgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt actgatcata ctttattggg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001839             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:21644:14066
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001839
VERSION     KCVO01001839.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:21644:14066"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..451
                     /note="immunoglobulin light chain variable region"
     V_region        130..451
     V_segment       130..417
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73868.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       421..451
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        452..>489
                     /gene="IGLC"
BASE COUNT           97 a          150 c          136 g          106 t
ORIGIN      
        1 acatggggga gagaagccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactccccc tcctcacttt ctgcacaggc
      121 tctgcagcct cctatgagct gacacagcca ccctcggtgt cagtgtcccc aggacagacg
      181 gccaggatca cctgctctgg agatgcattg ccagaaaaat ttgcttattg gttccagcag
      241 aagccaggcc agtcccctgt gctgatcatc aatgaggaca gcaaacggcc ctctgggatc
      301 cctgagagat tctctggctc cagttcaggg acagtggcca ccttgactct cagtggggcc
      361 caggtggagg atgaagctga ctactactgt tcctcaacag atagcagtgg taatcatgtt
      421 ttcggcggag ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact
      481 ctcttcccg
//
LOCUS       KCVO01001840             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:16923:18365
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001840
VERSION     KCVO01001840.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16923:18365"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73869.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           91 a          143 c          117 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gacgacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcat tggggcccag gtggaggatg aagctgacta ccactgtttc tcaacagata
      361 gcagtggtaa tcataggggc ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001841             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:14718:8601
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001841
VERSION     KCVO01001841.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:14718:8601"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73870.1"
                     /translation="DYHCYSTDISANHRGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           95 a          145 c          124 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgtatt
      181 gccaaaaaaa tatgcttctt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgacgac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actaccactg
      361 ttactcaaca gatatcagtg ctaatcatag gggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001842             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:14523:8789
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001842
VERSION     KCVO01001842.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:14523:8789"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..404
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73871.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           88 a          161 c          124 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt agtaaaaaca tgtactggta ccagcagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcaggt gtatgacagt actggagtgt tgttcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01001843             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:4334:8871
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001843
VERSION     KCVO01001843.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:4334:8871"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73872.1"
                     /translation="DYYCQVWDSSSDHCLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          143 c          139 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaac tgaatatgtg cactggtacc aacagaagcc agcgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctgc gcgattctct ggctccaaat
      301 cagggaatac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001844             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:21640:6398
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001844
VERSION     KCVO01001844.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:21640:6398"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73873.1"
                     /translation="DYYCYSIDINGNESIF"
     J_segment       395..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           95 a          139 c          122 g          107 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacaacc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttatt ggttccagca gaagccaggc cagtccccta tgctgatcat
      241 ctatgaggac agtgagcggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactattg
      361 ttactcaata gatatcaatg gtaatgagag cattttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001845             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:10910:19105
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001845
VERSION     KCVO01001845.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10910:19105"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..423
                     /note="immunoglobulin light chain variable region"
     V_region        101..423
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73874.1"
                     /translation="DYYCQVWDFSGDHNIF"
     J_segment       390..423
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>463
                     /gene="IGLC"
BASE COUNT           90 a          148 c          128 g           97 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatgacct ggacttttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggcc tcctctgagc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccagaatc acctgtggga gagacaacat
      181 tggaaataag aatgtgcact ggtaccagca gcggccaccg cgggccccta tactggtcat
      241 ctattatgat accgaacggc cctcagggat ccctgagcga ttctctggct ccacatcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gactttagtg gtgatcataa catcttcgat gctgggaccc ggctcaccgt
      421 cctcggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001846             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:12661:10245
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001846
VERSION     KCVO01001846.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:12661:10245"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73875.1"
                     /translation="DYYCSSYTSSSTWIF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           86 a          156 c          123 g          108 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actgggacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat catttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga tcatctctgg gttccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca gtagcacttg gatattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001847             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:6463:8228
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001847
VERSION     KCVO01001847.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:6463:8228"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73876.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           91 a          142 c          117 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggttct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gacgacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcat tggggcccag gtggaggatg aagctgacta ccactgtttc tcaacagata
      361 gcagtggtaa tcataggggc ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001848             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:16779:16436
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001848
VERSION     KCVO01001848.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:16779:16436"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73877.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           90 a          140 c          137 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagaatatgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccac gatcacctgt gggggagaca
      181 gcattggaag tagaagtgtg cagtggtacc agcagaagtc accgcaggcc cttctactgg
      241 tcatctatac tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggagcac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tattattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001849             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:10312:9129
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001849
VERSION     KCVO01001849.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:10312:9129"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73878.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       377..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           89 a          140 c          119 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaagtatg
      181 tttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 gacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag ggggaggatg aagctgacta ctactgttat tcaatggata
      361 gcagtggtac tcagagcatc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001850             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:15413:7663
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001850
VERSION     KCVO01001850.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15413:7663"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73879.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          145 c          123 g          100 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctctgagctg acacagccac
      121 cctcggtgtc agtgtccccc ggacagacgg ccaggatcac ctgctctgga aatgcattgc
      181 caaaatacta tgcttattgg ttccagcaga agccaggcca gtcccctgtg gcgatcatct
      241 atgaggacaa caaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc agtggggccc aggtagagga tgaggctgac tactactgtt
      361 actcaacaga tagcagtggt actaatggct tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001851             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:17897:19820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001851
VERSION     KCVO01001851.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17897:19820"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73880.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           84 a          158 c          125 g          108 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtggtt ataaccgtgt ctcctggtac cagcagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacgcaag cactagcact tggctattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001852             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:13430:22009
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001852
VERSION     KCVO01001852.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:13430:22009"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..436
                     /note="immunoglobulin light chain variable region"
     V_region        106..436
     V_segment       106..400
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73881.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       401..436
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           86 a          160 c          120 g          108 t
ORIGIN      
        1 acatgggggt gggatctcag gaggcagcac tctcaggacg tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagtctccct ctgtgtctgg gtctcctgga cagtcggtca ccatttcctg cactggaacc
      181 agcagtgaca ttggtggtta taaccgtgtc tcctggtacc aacagcaccc aggcaaagcc
      241 cccaaactca tgatttatga cgtcagtgat cggccctcag gggtctctga tcgcttctct
      301 ggttccaagt ctggcaacac ggcctccctg atcatctctg ggctccaggc tgaggacgag
      361 gctgattatt actgcagctc atacacaagc actaccactt ggctattcgg cggagggacc
      421 cgcctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001853             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:20274:8408
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001853
VERSION     KCVO01001853.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:20274:8408"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73882.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           88 a          161 c          126 g          108 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtactggagt gttgttcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01001854             450 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:14858:9911
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001854
VERSION     KCVO01001854.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 450)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14858:9911"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..412
                     /note="immunoglobulin light chain variable region"
     V_region        88..412
     V_segment       88..375
                     /gene="IGLV3-25"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>384
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73883.1"
                     /translation="DYYCDSWDSSGTHVLF"
     J_segment       376..412
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>450
                     /gene="IGLC"
BASE COUNT           88 a          136 c          126 g          100 t
ORIGIN      
        1 acatggggag agctctgggg tgtctccacc atggcctgga ctcctctctg gctcaccctc
       61 ctcagtcttt gcacaggttc tgtggtttct tctgagctga ctcaggaccc tgcagtgtct
      121 gtggccttgg gacagacagt caggatcact tgccaaggag acagcctcag aagctattat
      181 gcaagctggt accagcagaa gccaggccag gcccctgtgc tggtcgtcta tggtaacaac
      241 aaccggccct cagggatccc agagcgattc tctggctcca gctcaggaaa cacagcttcc
      301 ttgaccatca ctggggctca ggtggaagat gaggctgact attactgtga ctcctgggac
      361 agcagcggta cccatgtgtt attcggagga gggacccggc tgaccgtcct aggtcagccc
      421 aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001855             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:21118:19379
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001855
VERSION     KCVO01001855.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:21118:19379"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73884.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       377..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           90 a          141 c          118 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcaa aaaaagtatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacagca
      241 gacggccctc tgggatccct gagagattct ctgcctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag ggggaggatg aagctgacta ctactgttat tcaatggata
      361 gcagtggtac tcagagcatc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001856             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:25146:8881
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001856
VERSION     KCVO01001856.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:25146:8881"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73885.1"
                     /translation="DYYCAAWDDSLNSPFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          156 c          114 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaac
      181 attggaagta attatgtaaa ctggtaccag caactcccag gaacggcccc caaactcctc
      241 atctatttta ctaatcagcg accctcaggg gtccctgacc gcttctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcggcat gggatgacag cctgaacagt cccttcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001857             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:18418:8014
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001857
VERSION     KCVO01001857.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18418:8014"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73886.1"
                     /translation="DYYCQVWDSSSDHPIF"
     J_segment       396..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           81 a          146 c          139 g          102 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acagtctctg cggtctccta tgagctgact
      121 cagccaccct cggtgtcagt gtccccagga cggacggcca ggatcacgtg tgggggagac
      181 atcgttggaa gtgaatatgt tcactggtat cagcagaagt cagcgcaggc ccctgtggtg
      241 gtcatctatt attattctga ccggccctca gggatccctg agcgattctc tggctccaaa
      301 tcagggagca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactac
      361 tactgtcagg tgtgggacag tagtagtgat catcccatct tcggtgctgg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCVO01001858             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:21584:4369
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001858
VERSION     KCVO01001858.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:21584:4369"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73887.1"
                     /translation="DYYCSSTDSSGIYVF"
     J_segment       378..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           89 a          140 c          117 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtact gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gggagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag atggaggatg aagctgacta ctactgttcc tcaacagata
      361 gtagtggtat ttatgtgttc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001859             364 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:5394:14671
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001859
VERSION     KCVO01001859.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 364)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 364)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:5394:14671"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..326
                     /note="immunoglobulin light chain variable region"
     V_region        8..326
     V_segment       8..288
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <251..>298
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73888.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       292..326
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        327..>364
                     /gene="IGLC"
BASE COUNT           78 a          108 c          102 g           76 t
ORIGIN      
        1 acatggggag ctgacacagc caccctcggt gtcagtgtcc ccaggacaga cggccaggat
       61 cacctgctct ggagatgcat tgccaaaaaa gtatgcttat tggttccagc agaagccagg
      121 ccagtcccct gtgctgatca tctatgagga cagcagacgg ccctctggga tccctgagag
      181 attctctgcc tccagctcag ggacagtggc caccttgact atcagtgggg cccaggggga
      241 ggatgaagct gactactact gttattcaat ggatagcagt ggtactcaga gcatcttcgg
      301 tgctgggacc cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt
      361 cccg
//
LOCUS       KCVO01001860             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:11964:5054
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001860
VERSION     KCVO01001860.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11964:5054"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73889.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           94 a          142 c          125 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagac
      121 tccctcggtg tcagtgtccc caggacagac ggccaggatc tcctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaaggcaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagttcagg
      301 gacaatggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gataacagtg atactcatag gggcttcttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001861             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:18396:16127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001861
VERSION     KCVO01001861.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:18396:16127"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73890.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           87 a          155 c          122 g          109 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acaacaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca gtagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001862             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:11063:8775
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001862
VERSION     KCVO01001862.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:11063:8775"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73891.1"
                     /translation="DYYCYSTENSDTHRGFF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          143 c          127 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc tcctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaaggcaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagttcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gagaacagtg atactcatag gggcttcttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001863             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:11452:4403
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001863
VERSION     KCVO01001863.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:11452:4403"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73892.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       392..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           89 a          140 c          138 g           95 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctta ctgcacagac tctgcggtct cctatgacct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg agacaatgtt
      181 ggaagtgaat atgtgcactg gtaccaacag aaaccagcgc aggcccctgt ggtggtcatc
      241 cattataata gtgaccggcc ctcagggatc cctgagcgat tctctggctc caaatcaggg
      301 aacaccgcca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtagtag tgatcattgt gtattgggag gagggacccg gctgaccgtc
      421 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001864             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:9275:16647
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001864
VERSION     KCVO01001864.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:9275:16647"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..309
                     /note="immunoglobulin light chain variable region"
     V_region        87..309
     V_segment       87..269
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>281
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73893.1"
                     /translation="EYHCFSTDSSGNHRGLF"
     J_segment       273..309
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        310..>347
                     /gene="IGLC"
BASE COUNT           67 a          106 c           97 g           77 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagc agaagccagg ccagtcccct gtgctgatca
      121 tctatgacga cagcaaacgg ccctctggga tccctgagag attctctggc tccagctcag
      181 ggacagtggc caccttgact atcattgggg cccaggtgga ggatgaagct gagtaccact
      241 gtttctcaac agatagtagt ggtaatcata ggggcttatt cggaggaggg acccggctga
      301 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001865             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:8147:11861
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001865
VERSION     KCVO01001865.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:8147:11861"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73894.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       402..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           87 a          155 c          124 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagtacc caggcaaagc
      241 ccccaaagtc atcatttatg aggtcagtga tcggccctca ggggtctctg atcgcttcac
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacacaag cagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001866             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:12834:12369
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001866
VERSION     KCVO01001866.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:12834:12369"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73895.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       395..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           87 a          143 c          139 g           97 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gtctcctatg agctcactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggaggcaa
      181 tgttggaagt gaatatgtcc actggtatca acagaagcca ccgcaggccc ctgtggtggt
      241 catctattat aatactgacc ggccctcagg gatccctgag cgattctctg gctccaaatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta ggagtgatca tagtttattg ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001867             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:16778:6587
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001867
VERSION     KCVO01001867.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16778:6587"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73896.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       392..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           90 a          142 c          125 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgtagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tttgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagttcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagcagtg gtaatcatgt tttcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001868             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:16535:18055
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001868
VERSION     KCVO01001868.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16535:18055"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73897.1"
                     /translation="VYYCQSYDTRLRAWVF"
     J_segment       410..446
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           91 a          158 c          126 g          109 t
ORIGIN      
        1 acatggggct ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct cctctcctcc tcacccttct cagtcactgc acagggtcct gggcccagtc
      121 tgtcctgacg cagccgccct cagtgtctgg ggcgcccggg cagagggtca ccatctcctg
      181 cactgggagc agctccaaca ttggagatta ttttgtgcag tggtaccaac agcttccagg
      241 aacggccccc aaactcctca tctatgaaaa tgataaacgg ccctcaggag tttctgatcg
      301 attctctggc tcccagtctg gaacctcagc ctccctgacc atcactggac tccagtctga
      361 ggatgagact gtttattact gccagtccta tgacaccaga ttgagggctt gggtattcgg
      421 cggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCVO01001869             431 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:11383:10411
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001869
VERSION     KCVO01001869.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 431)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:11383:10411"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73898.1"
                     /translation="DYHCSSTDSSDYHRVLF"
     J_segment       380..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>431
                     /gene="IGLC"
BASE COUNT           87 a          131 c          114 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgaactgac acagccaccc tcggtgtcag
      121 cgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aataaatttg
      181 cttcttggtt tcagcagaag ccaggccagc cccctgttct gatcatctat gatgacagca
      241 aacggccatc tgggatccct gagagattct ctggctctag ctcaggggca gtggccacct
      301 tgagtgtcag tggggcccag gtggaggatg aggctgacta ccactgttcc tcaacagatt
      361 ccagtgatta tcatagggtc ttattcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc c
//
LOCUS       KCVO01001870             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:4795:13921
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001870
VERSION     KCVO01001870.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:4795:13921"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73899.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           87 a          155 c          121 g          110 t
ORIGIN      
        1 acatggtctg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagtaccca ggcaaagccc
      241 ccaaagtcat catttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttcactg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca gtagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001871             477 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:7776:18127
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001871
VERSION     KCVO01001871.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 477)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:7776:18127"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    94..438
                     /note="immunoglobulin light chain variable region"
     V_region        94..438
     V_segment       94..403
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>411
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73900.1"
                     /translation="DYYCLIWHNNVWVF"
     J_segment       404..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>477
                     /gene="IGLC"
BASE COUNT           94 a          155 c          113 g          115 t
ORIGIN      
        1 acatggggcc actgcaggga aagaggctgt gtccaccatg gcctggactc ctctctcctc
       61 ctgctcctct ctcactgcac aggttccctc tcgcagcctg cgctgactca gccaacctcc
      121 ctctcagcat ctcctggagc atcagccaga ttcacctgca ccttgagcag aggcatcagt
      181 gttgctattt ataggatatt ctggtaccag cagaagccag ggagtcctcc ccggtatctt
      241 ctgaactccc acacagactc agataaacac cagggctctg gagtccccag ccgcttctct
      301 ggatccaaag atgcttcggc caatgcaggg attttactca tctctggcct ccagtctgag
      361 gatgaggctg actattactg tttgatttgg cacaacaatg tttgggtttt cggcggaggg
      421 acccggctga ccgtcctaag tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001872             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:14040:5651
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001872
VERSION     KCVO01001872.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:14040:5651"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..404
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73901.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       406..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           91 a          153 c          126 g          110 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcaat gtctggggcg cccgggcagg gggtcaccat ctcctgcact
      181 gggagcagct ccaatattgg agattattat gtgcagtggt accaacagtt tccaggaacg
      241 gcccccagac tcctcatcta tgaaaataat aaacgaccct caggggtttc tgatcgattc
      301 tctggctccc agtctggtac ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attattgcca gtcctatgac agcagcctga gtgccgtgtt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001873             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:21504:9056
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001873
VERSION     KCVO01001873.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:21504:9056"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73902.1"
                     /translation="DYYCYSADSSGNGLF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           95 a          139 c          125 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcgtatt ggtatcagca gaaaccaggc cagtcccctg tgcatatcat
      241 ctatgatgac agcaagcggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagtagtg gtaatggctt attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001874             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:10976:6799
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001874
VERSION     KCVO01001874.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:10976:6799"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73903.1"
                     /translation="DYYCYSMDSSGSQSIF"
     J_segment       391..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          143 c          124 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccaaca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcgaacggc cctctgggat ccctgagaga ttctctgcct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaatg gatagtagtg gtagtcagag catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001875             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:23101:14976
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001875
VERSION     KCVO01001875.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:23101:14976"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..406
                     /note="immunoglobulin light chain variable region"
     V_region        87..406
     V_segment       87..372
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73904.1"
                     /translation="DYYCYSPDNSGNRAF"
     J_segment       377..406
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>446
                     /gene="IGLC"
BASE COUNT           92 a          141 c          116 g           97 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggta ccagcagaaa ccaggccagt cccctgtact gatcatctat gaggacagtc
      241 aacggtcctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttat tccccagaca
      361 acagtggaaa tcgggcattc ggcggaggga cccggctgac cgtcctgggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001876             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:28538:10382
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001876
VERSION     KCVO01001876.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:28538:10382"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73905.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           88 a          141 c          118 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatcaat gaggacagca
      241 aacggccctc tgggatccct gggagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gtagtggtaa ttatgtattc ggcggcggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001877             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:14743:6045
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001877
VERSION     KCVO01001877.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:14743:6045"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    89..417
                     /note="immunoglobulin light chain variable region"
     V_region        89..417
     V_segment       89..383
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <347..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73906.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       384..417
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        418..>457
                     /gene="IGLC"
BASE COUNT           83 a          152 c          116 g          106 t
ORIGIN      
        1 acatggggag cactctcagg acgtctccac catggcctgg gctctgctcc tcctcaccct
       61 cctcactcag ggcacaggat cctgggctca ggctgccctg actcagtctc cctctgtgtc
      121 tgggtctcct ggacagtcgg tcaccatttc ctgcactgga accagcagtg acattggtga
      181 ttataaccgt gtctcctggt accaacagca cccaggcaaa gcccccaaac tcatgattta
      241 tgaggtcagt gatcggccct caggggtctc tgatcgcttc tctggttcca agtctggcaa
      301 cacggcctcc ctgatcatct ctgggctcca ggctgaggac gaggctgatt attactgcag
      361 ctcatacaca agcagtagca cttgggtatt cggcggaggg acccggctga ccgtccttgg
      421 tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001878             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:19861:7301
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001878
VERSION     KCVO01001878.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:19861:7301"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..289
                     /note="immunoglobulin light chain variable region"
     V_region        7..289
     V_segment       7..244
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <214..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73907.1"
                     /translation="DYYCQVWDSITAQWVF"
     J_segment       253..289
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>327
                     /gene="IGLC"
BASE COUNT           67 a           95 c          101 g           64 t
ORIGIN      
        1 acatggggac agacggcccg gatcacctgt gggggagaca acattggaag taaaagtgtg
       61 cagtggttcc agcagaggcc accgcaggcc cctgtgctgg tcatttatac tgataaccag
      121 cggccctcag ggatccctga gcgattctct ggctccaact cagggaacac cgccaccctg
      181 accatcagcg gggtcgaggc cgggaatgag gctgactatt attgtcaggt gtgggacagt
      241 attactgctc agtgggtatt cggcggaggg acccggctga ccgtcctagg tcagcccaag
      301 gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001879             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:20278:10845
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001879
VERSION     KCVO01001879.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20278:10845"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73908.1"
                     /translation="DYYCQVWDTNKDHIFF"
     J_segment       399..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          148 c          133 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctgt gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaga taaatatcta cactggtacc accagaagcc agcgcaggcc cctgtgctgg
      241 tcatctacta taatagtgac cggccctcat ggatccctga gcgattctct gggtccaagt
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacact aataaagatc atatcttttt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001880             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:10515:15557
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001880
VERSION     KCVO01001880.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:10515:15557"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..383
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73909.1"
                     /translation="DYYCYSADSSGTGLF"
     J_segment       385..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          142 c          126 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccacaaaaa tatgcttatt ggtgccagca gaaaccaggc cagtcccctg tggtgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacagcagtg gtactggctt attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001881             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:16213:20277
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001881
VERSION     KCVO01001881.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:16213:20277"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    88..408
                     /note="immunoglobulin light chain variable region"
     V_region        88..408
     V_segment       88..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73910.1"
                     /translation="DYYCYSGDSSGDGFF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           89 a          138 c          119 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacagtctct gcagccgcct atgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaattatg
      181 cgtattggta ccagcagaaa ccaggccagt cccctgtgtt gatcatctct gacgacaaca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcggggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttat tcaggagaca
      361 gcagtggtga tggctttttc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001882             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:21174:12185
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001882
VERSION     KCVO01001882.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:21174:12185"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73911.1"
                     /translation="DYYCYSTDSGRNHLF"
     J_segment       392..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          142 c          123 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggctc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac aacaaacggc cctctgggat gtctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggttgag gatgaagctg actactactg
      361 ttactcaaca gatagcggtc gtaatcactt gttcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001883             288 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:4509:12725
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001883
VERSION     KCVO01001883.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 288)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:4509:12725"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..250
                     /note="immunoglobulin light chain variable region"
     V_region        7..250
     V_segment       7..214
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <178..>222
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73912.1"
                     /translation="DYYCSSYADTTTWLF"
     J_segment       215..250
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        251..>288
                     /gene="IGLC"
BASE COUNT           56 a           95 c           72 g           65 t
ORIGIN      
        1 acatggggtg gttataaccg tgtctcctgg taccaacagc acccaggcaa agcccccaaa
       61 ctcatgattt atgacgtcag tgatcggccc tcaggggtct ctgatcgctt ctctggttcc
      121 aagtctggca acacggcctc cctgatcatc tctgggctcc aggctgagga cgaggctgat
      181 tattactgca gctcatacgc agacactacc acttggctat tcggcggagg gacccgcctg
      241 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001884             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:24855:12026
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001884
VERSION     KCVO01001884.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:24855:12026"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73913.1"
                     /translation="DYYCYSRDSSGYLGVF"
     J_segment       391..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           94 a          138 c          128 g          104 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggaaatgcat
      181 tgccaaaaaa atatgcttat tggttccagc agaagccagg ccagtcccct gtgttgatca
      241 tcaatgagga cagcaaacgg ccctctggga tccctgagag attctctggc tccagctcag
      301 ggacagtggc caccttgact atcagtgggg cccaggtgga ggatgaagct gactattact
      361 gttactcaag agatagtagt ggttatcttg gggtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001885             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:8134:6734
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001885
VERSION     KCVO01001885.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8134:6734"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73914.1"
                     /translation="DYYCFSSDSSADYWVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>449
                     /gene="IGLC"
BASE COUNT           87 a          140 c          119 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggttccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgtttc tcatcagata
      361 gcagtgctga ttattgggtg ttcggcggag ggacccggct gaccgtccca ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001886             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:8275:2611
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001886
VERSION     KCVO01001886.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:8275:2611"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73915.1"
                     /translation="DYYCFSSDRSSDHWVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           92 a          140 c          127 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac aggaaacggt cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacaatggcc accttgacta tcagtggggc ccaggtggag gatgaaggtg actactactg
      361 tttctcatca gatagaagtt ctgatcattg ggtgttcggc ggagggaccc ggctgaccgt
      421 cccaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001887             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:15434:10926
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001887
VERSION     KCVO01001887.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:15434:10926"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73916.1"
                     /translation="DYYCSSYAGSGTLLF"
     J_segment       400..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           86 a          157 c          127 g          102 t
ORIGIN      
        1 acatgggggg ggtctcagga gacagcactt gcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctccctct gtgtccgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa caacacccag gcaaagcccc
      241 caaagtcacg atttatgagg tcagtgagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtca ggcaacacgg cctccctgag catctctggc ctccaggctg aggacgaggc
      361 tgattattac tgcagttcat atgcaggcag cggcactttg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001888             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:8303:5009
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001888
VERSION     KCVO01001888.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:8303:5009"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..450
                     /note="immunoglobulin light chain variable region"
     V_region        117..450
     V_segment       117..410
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73917.1"
                     /translation="DYHCSLWDSRLSSRVF"
     J_segment       415..450
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           94 a          159 c          127 g          108 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctctcctt ctcactctgc tggttcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagcatctg gggcccccgg gcagagggtc accatctcct
      181 gcactgggac cagctccaac atcggggcga attattatgt ttcctggtac caacagttcc
      241 caggaacagc ccccaaactc ctcatctatg aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggttcct cagcctccct gaccatctct ggactccaat
      361 ctgacgatga ggctgactat cactgctcac tatgggatag caggctgagt agtcgggtat
      421 tcggcggagg gacccgactg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCVO01001889             295 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:22256:12426
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001889
VERSION     KCVO01001889.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 295)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:22256:12426"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..257
                     /note="immunoglobulin light chain variable region"
     V_region        8..257
     V_segment       8..221
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <185..>229
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73918.1"
                     /translation="DYYCSSYASSSTWIF"
     J_segment       222..257
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        258..>295
                     /gene="IGLC"
BASE COUNT           61 a           92 c           76 g           66 t
ORIGIN      
        1 acatggggac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
       61 ccccaaactc ataatttatg aggtcagtga tcggccctca ggggtctctg atcgcttctc
      121 tggctccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      181 ggctgattat tactgcagct catacgcaag cagtagcact tggatattcg gcggagggac
      241 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001890             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:9044:8700
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001890
VERSION     KCVO01001890.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:9044:8700"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..443
                     /note="immunoglobulin light chain variable region"
     V_region        110..443
     V_segment       110..403
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73919.1"
                     /translation="DYYCSLWDSRLSSRVF"
     J_segment       408..443
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           93 a          152 c          128 g          108 t
ORIGIN      
        1 acatgggggg cttcagatgt gggcacagga ggcagcactc aggacagtct ccagcatggc
       61 ctggtctctc cttctcactc tgctggttca ctgcacaggg tcctgggccc agtctgtgct
      121 gacgcagccg ccctcagcat ctggggcccc cgggcagagg gtcaccatct cctgcactgg
      181 gaccagttcc aacatcgggg cgaattatta tgtttcctgg taccagcagt tcccaggaac
      241 agcccccaaa ctcctcatct atgaaaataa taagcgaccc tcaggggttt ctgaccgatt
      301 ctctggctcc aagtctggta cctcagcctc cctgaccatc tctggactcc aatctgagga
      361 tgaggctgat tattactgct cactatggga tagcaggctg agtagtcggg tattcggcgg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01001891             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:16501:5102
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001891
VERSION     KCVO01001891.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16501:5102"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73920.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       402..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           86 a          155 c          124 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacacaag cagtagtact tgggtattcg gcggagggac
      421 ccggctgacc gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001892             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:18050:9057
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001892
VERSION     KCVO01001892.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:18050:9057"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..435
                     /note="immunoglobulin light chain variable region"
     V_region        87..435
     V_segment       87..395
                     /gene="IGLV5-73"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73921.1"
                     /translation="DYYCAIGHSSGDYIF"
     J_segment       398..435
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           94 a          155 c          117 g          107 t
ORIGIN      
        1 acatgggggg gaaagaggct gtgtccacca tggcctggac tcctctcctc ctcctgctcc
       61 tctctcactg cacaggttcc ctctccaagc ctatgctgac tcagccggcc tccctctcag
      121 catctcctgg agcatcagcc agtctcacat gcaccttcag cggtggcatc aatgttgctg
      181 gctaccacat acactggtac cagcagaagc cagggagtcc tccccggtat cttctgagat
      241 acaaatcaga ctcagataag ggccagggct ctggagtccc cagccgcttc tctggatcca
      301 aagatggttc agcgaacaca gggattttac gcatctctgg gctccagtct gaggatgagg
      361 ctgactatta ctgtgccatt ggacacagca gcggtgatta catcttcggt gctgggaccc
      421 ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001893             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:17424:8255
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001893
VERSION     KCVO01001893.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:17424:8255"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73922.1"
                     /translation="DYFCQVWDSTNKYVLF"
     J_segment       396..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          148 c          134 g           96 t
ORIGIN      
        1 acatgggggc ctgactttgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactgcac aggctctgtg gcctcctatg agctgactca
      121 gccaccctcg gtgtcggtgt ccccaggaca gacagccagg atcacctgtg ggggagacaa
      181 cattggacgt gaaagtgtgc actggtacca acagaagcca ccgcaggccc ctctgttggt
      241 catatattct ggtggcgaac ggccctcagg gatccctgag cgattctctg cctccatctc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactattt
      361 ctgtcaggtg tgggacagta ctaataaata cgtactattc ggaggaggga cccgactgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001894             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:22294:9919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001894
VERSION     KCVO01001894.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:22294:9919"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..372
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73923.1"
                     /translation="DYYCYSMDSSTYLGFF"
     J_segment       374..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           90 a          143 c          115 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatacg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacacca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaatggata
      361 gcagtactta tcttggcttc ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001895             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:2641:10904
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001895
VERSION     KCVO01001895.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:2641:10904"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..444
                     /note="immunoglobulin light chain variable region"
     V_region        115..444
     V_segment       115..407
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73924.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       409..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>483
                     /gene="IGLC"
BASE COUNT           91 a          155 c          127 g          110 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gcgcccgggc agagggtcac catctcctgc
      181 actgggagca gctccaacat tggaggttat tatgtgcagt ggtaccagca acttccagga
      241 acggccccca aagttctcat ctatgaaaat aataagcgac cctcaggggt ttctgatcga
      301 ttctctggct cccagtctgg tacctcagcc tccctgacca tcactggact ccagtctgag
      361 gatgaggctg attattactg ccagtcctat gacagcagcc tgagtgccgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaagtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01001896             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:26952:20657
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001896
VERSION     KCVO01001896.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:26952:20657"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    129..450
                     /note="immunoglobulin light chain variable region"
     V_region        129..450
     V_segment       129..416
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73925.1"
                     /translation="DYYCSSTDRSGNHVF"
     J_segment       417..450
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT          100 a          150 c          135 g          103 t
ORIGIN      
        1 acatggggag agaagcctag ggagcccagc tgtgctgtgg gctcaggagg cagagctctg
       61 ggtgtctcac catggcctgg attcctctcc tactccccct cctcactttc tgcacaggct
      121 ctgcagcctc ctatgagctg acacagccac cctcggtgtc agtgtcccca ggacagacgg
      181 ccaggatcac ctgctctgga gatgcattgc cagaaaaata tgcttattgg ttccagcaga
      241 agccaggcca gtcccctgtg ctgatcatca atgaggacag caaacggccc tctgggatcc
      301 ctgagagatt ctctggctcc agctcaggga cagtggccac cttgactctc agtggggccc
      361 aggtggagga tgaagctgac tactactgtt cctcaacaga tagaagtggt aatcatgtat
      421 tcggcggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCVO01001897             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:21030:12471
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001897
VERSION     KCVO01001897.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:21030:12471"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..383
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73926.1"
                     /translation="DYYCQVWDSISDQWVF"
     J_segment       390..426
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           84 a          145 c          141 g           94 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactgcacag gctctgcggt ctcctatgag ctgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggcccggat cacctgtggg ggagacaaca
      181 ttggaagtaa aagtgtgcag tggttccagc agaagccacc gcaggcccct gtgttggtca
      241 tttatactga tagcgagcgg ccctcaggga tccctgagcg attctctggc tccaactcag
      301 ggaacatcgc caccctgacc atcagcgggg tcgaggccgg gaatgaggct gactattact
      361 gtcaggtgtg ggacagcatt agtgatcagt gggtattcgg cggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001898             330 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:19953:13686
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001898
VERSION     KCVO01001898.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 330)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 330)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..330
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:19953:13686"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    73..292
                     /note="immunoglobulin light chain variable region"
     V_region        73..292
     V_segment       73..252
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <217..>264
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73927.1"
                     /translation="DYYCYSTISSGNERIF"
     J_segment       259..292
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        293..>330
                     /gene="IGLC"
BASE COUNT           66 a          102 c           86 g           76 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacagcagaa gccaggccag tcccctgtgt tgatcatcta tgaggacagc
      121 aaacggccct ctgggatccc tgagagattc tctggctcca gctcagggac agtggccacc
      181 ttgactatca gtggggccca ggtggaggat gaagctgact actactgtta ctcaacaatt
      241 agtagtggta atgaaaggat cttcggtgct gggacccggc tcaccgtcct aggtcagccc
      301 aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01001899             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:14896:8640
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001899
VERSION     KCVO01001899.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14896:8640"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73928.1"
                     /translation="DYYCYSSDSTADYWVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>449
                     /gene="IGLC"
BASE COUNT           88 a          139 c          118 g          104 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gattatttat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggttccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtgcaggatg aagctgacta ctactgttac tcatcagata
      361 gcactgctga ttattgggtg ttcggcggag ggacccggct gaccgtccca ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001900             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:10160:8698
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001900
VERSION     KCVO01001900.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:10160:8698"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73929.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           83 a          158 c          119 g          115 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagctgtgac atcggtactt ataactatgt ctcctggtac caacagcatc caggcacagc
      241 ccccaaactc ataatttttg aggtcagtga gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgttgct catatgcaga cacctacact tttgtgtttg gacgtggcac
      421 cagattgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001901             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:17020:9193
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001901
VERSION     KCVO01001901.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:17020:9193"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..430
                     /note="immunoglobulin light chain variable region"
     V_region        97..430
     V_segment       97..390
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73930.1"
                     /translation="DYYCLSYDSSLSAHYIF"
     J_segment       393..430
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           93 a          160 c          111 g          104 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctcgtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtcc tgggcccagt ctgtgctgac acagccaccc
      121 tcagtgtctg gggccccagg gcagagggtc accatctcgt gcactgggag cagctccagc
      181 attggaggtg attatgtatc ctggtaccaa cagctcccag gaacgacccc caaactcctc
      241 atctatcaaa ataataagct accctcaggg gtttctgacc gattctctgg ctccaagtct
      301 ggtacctcag cctccctgac catcactggg ctccagactg aggatgaggc tgattactac
      361 tgcctgtcct atgacagcag cctgagtgct cattacatct tcggtcctgg gacccggctc
      421 accgtcctag gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCVO01001902             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:22478:11958
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001902
VERSION     KCVO01001902.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22478:11958"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..443
                     /note="immunoglobulin light chain variable region"
     V_region        119..443
     V_segment       119..405
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73931.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       409..443
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           93 a          149 c          132 g          107 t
ORIGIN      
        1 acatggggag ggagcccagc tgtgctgtgg gctcaggagg cagagctctg ggtgtctcac
       61 catggcctgg attcctctcc tactccccct cctcactttc tgcacaggct ctgcagcctc
      121 ctatgagctg acacagccac cctcggtgtc agtgtcccca ggacagacgg ccacgatcac
      181 ctgctctgga gatgcattgc caaaaaagtt tgcttattgg ttccagcaga agccaggcca
      241 gtcccctctg ctgatcatct atgaggacag cagacggccc tctgggatcc ctgagagatt
      301 ctctggctcc agttcaggga cagtggccac cttgactatc agtggggccc agggggagga
      361 tgaagctgac tactactgtt attcaatgga tagcagtggt actcagagca tcttcggtgc
      421 tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca ctctgttccc
      481 g
//
LOCUS       KCVO01001903             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:15918:9268
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001903
VERSION     KCVO01001903.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:15918:9268"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV10-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73932.1"
                     /translation="DYYCSAWDSSLSAVLF"
     J_segment       398..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT          107 a          156 c          124 g           85 t
ORIGIN      
        1 acatggggaa agcagagctt cggcaagcac agtgggaatc cgcaccatgc cctgggctct
       61 gctcctcctg accctcctca ctcactctgc agtgccagtg gtccaggcag ggctgactca
      121 gccaccctca gtgtccaagg gcttgagaca gacggccaca ctcacctgca ctggaaatag
      181 caacaatgtt ggcaaccagg gagcaggttg gctgcagcag caccagggcc accctcccaa
      241 actgctgtcc tacaggaata acaaccggcc ctcgggaatc tcagagagat tctctgcatc
      301 caggtcagga aatacagcct ccctgaccat caccggactc caacctgagg atgaggctga
      361 ctattactgc tcagcatggg acagcagcct cagtgctgtg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001904             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:4042:17065
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001904
VERSION     KCVO01001904.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:4042:17065"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..398
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73933.1"
                     /translation="EYYCSSYADIYTFVF"
     J_segment       399..433
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           86 a          161 c          116 g          108 t
ORIGIN      
        1 acatgggggg gtctcagacg gcagcgctct cgggacatct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggc ctcaggctgc cctgactcag
      121 cctcgctcag tgtctgggtc tcctggacag tcggtcacca tctcctgcac gggcaccagc
      181 agtgacatcg gtggttacaa ctttgtctcc tggtaccaac accatccaga cacagccccc
      241 aaactcgtga tttatgaggt cactcagcgg ccctcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc tccaggctga ggacgaggct
      361 gaatattact gcagttcata tgcagacatc tacacatttg tgttcggaag tggcaccaaa
      421 ttgaccgtcc tcggtcagcc caaggcttcc cccttggtca ctctgttccc g
//
LOCUS       KCVO01001905             415 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:15478:5807
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001905
VERSION     KCVO01001905.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 415)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:15478:5807"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..377
                     /note="immunoglobulin light chain variable region"
     V_region        87..377
     V_segment       87..337
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <305..>349
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73934.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       341..377
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        378..>415
                     /gene="IGLC"
BASE COUNT           90 a          127 c          111 g           87 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagt gtccccagga cagacggcca ggatcacctg
      121 ctctggagat gcattgccag aaaaatatgc ttattggtac cagcagaaac caggccagtc
      181 ccctatgctg atcatctatg aggacaacaa acggccctct gggatccctg aaagattctc
      241 tggctccagc tcagggacag tggccacctt gactatcact ggggcccagg tggaggatga
      301 agctgactac tactgttact cagcagacaa cagtggtcag ggctcattcg gaggagggac
      361 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001906             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:20115:11104
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001906
VERSION     KCVO01001906.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:20115:11104"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73935.1"
                     /translation="DYYCYSSDSSADYWVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>449
                     /gene="IGLC"
BASE COUNT           88 a          139 c          120 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggttccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcatcagata
      361 gcagtgctga ttattgggtg ttcggcggag ggacccggct gaccgtccca ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001907             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:6927:4467
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001907
VERSION     KCVO01001907.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:6927:4467"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73936.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       391..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          143 c          125 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tactgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactg tcagtggggc ccagggggag gatgaagctg actactactg
      361 ttattcaatg gatagcagtg gtactcaaag catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001908             333 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:25083:8481
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001908
VERSION     KCVO01001908.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 333)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:25083:8481"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    2..293
                     /note="immunoglobulin light chain variable region"
     V_region        2..293
     V_segment       2..253
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <217..>267
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73937.1"
                     /translation="DYYCQSSDTSLNDHVLF"
     J_segment       258..293
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        294..>333
                     /gene="IGLC"
BASE COUNT           74 a          103 c           78 g           78 t
ORIGIN      
        1 acatgggaga gggtcaccat ctcctgcact gggagcagct ccaatattgg aggttattat
       61 gtatactggt accagcaact cccaggaatg gcccccaaac tcctcatcta tgacaataat
      121 aagcggccct caggggtttc tgaccgattc tctggctcca agtctggtac ctcagcctcc
      181 ctgaccatca ctgggctcca gactgaggat gaggctgatt attactgcca atcctctgac
      241 accagcctaa atgatcatgt gttattcgga ggagggaccc gactgaccgt cctcggtcag
      301 cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001909             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:19697:19549
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001909
VERSION     KCVO01001909.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:19697:19549"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73938.1"
                     /translation="DYYCGAWDSSLNTRLF"
     J_segment       409..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           92 a          158 c          127 g          105 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gtgtctgggg accccgggca gagggtcacc atctcgtgca
      181 ctgggagcag ctccaacatt ggaggttatc ttgtatactg gtaccagcag ttcccaggaa
      241 cagcccccaa actcctcatc tatgacaata ataagcgacc ctcagggatt tctgaccgat
      301 tctctggctc caagtctggt acctcagcct ccctgaccat cactgggctc cagcctgggg
      361 atgaggctga ttactactgc ggagcatggg atagcagcct gaatactcgc ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001910             454 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:13350:5602
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001910
VERSION     KCVO01001910.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 454)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:13350:5602"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..416
                     /note="immunoglobulin light chain variable region"
     V_region        114..416
     V_segment       114..380
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <344..>388
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73939.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       381..416
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        417..>454
                     /gene="IGLC"
BASE COUNT           85 a          154 c          115 g          100 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctcctgga cagtcggtca ccatttcctg cactggaacc agcagtgaca ttggtggtta
      181 taaccgtgtc tcctggtacc aacagcaccc aggcaaagcc cccaaactca tgatttatga
      241 cgtcagtgat cggccctcag gggtctctga tcgcttctct ggttccaagt ctggcaacac
      301 ggcctccctg atcatctctg ggctccaggc tgaggacgag gctgattatt actgcagctc
      361 atacgcaagc actaccactt ggctattcgg cggagggacc cgcctgaccg tcctaggtca
      421 gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001911             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:23850:14272
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001911
VERSION     KCVO01001911.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:23850:14272"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..451
                     /note="immunoglobulin light chain variable region"
     V_region        130..451
     V_segment       130..417
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73940.1"
                     /translation="DYYCSSRDSSGNYVF"
     J_segment       418..451
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        452..>489
                     /gene="IGLC"
BASE COUNT           99 a          148 c          137 g          105 t
ORIGIN      
        1 acatggggaa gagaagccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactccccc tcctcacttt ctgcacaggc
      121 tctgcagcct cctatgagct gacacagcca ccctcggtgt cagtgtcccc aggacagacg
      181 gccaggatca cctgctctgg agatgcattg ccagaaaaat ttgcttattg gttccaacag
      241 aagccaggcc agtcccctgt gctgatcatc aatgaggaca gcaagcggcc ctctgggatc
      301 cctgagagat tctctggctc cagctcaggg acagtggcca ccttgactct cagtggggcc
      361 caggtggagg atgaaggtga ctactactgt tcctcaagag atagcagtgg taattatgta
      421 ttcggcggag ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact
      481 ctcttcccg
//
LOCUS       KCVO01001912             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:10023:16002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001912
VERSION     KCVO01001912.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10023:16002"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73941.1"
                     /translation="DYYCYSADSSGNGLF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           93 a          137 c          118 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cgtattggta tcagcagaaa ccaggccagt cccctgtgca tatcatctat gaggacagca
      241 agcggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 gtagtggtaa tggcttattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001913             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:18622:10815
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001913
VERSION     KCVO01001913.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:18622:10815"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73942.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          160 c          121 g          106 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gcccgcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcac taccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001914             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:12121:1823
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001914
VERSION     KCVO01001914.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12121:1823"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73943.1"
                     /translation="DFHCYSADSSGNWVF"
     J_segment       372..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           90 a          139 c          119 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggta ccagcagaaa ccaggccagt cccctgtgct gatcatctat gaggacagta
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactgtcag tggggcccag gtggaggatg aagctgactt ccactgttac tcagcagaca
      361 gcagtggtaa ttgggtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001915             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:22744:18854
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001915
VERSION     KCVO01001915.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22744:18854"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..409
                     /note="immunoglobulin light chain variable region"
     V_region        87..409
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73944.1"
                     /translation="DYYCYSSDISGNHRVF"
     J_segment       376..409
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>449
                     /gene="IGLC"
BASE COUNT           92 a          138 c          116 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaagacagta
      241 aacggccctc tgggatccct gagagattct ctggctccag ttcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcatcagata
      361 tcagtggtaa tcatagggta ttcggcggag ggacccggct gaccgtcctt ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01001916             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:12611:21777
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001916
VERSION     KCVO01001916.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:12611:21777"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73945.1"
                     /translation="HYYCSSYAGTSTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           87 a          156 c          122 g          108 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat aatttatgag gtcagtaatc ggccctcagg ggtctctgat cgcttctctg
      301 gttctaagtc tggcaacacg gcctccctga gcatctctgg gctccaggct gaggacgagg
      361 ctcattatta ctgcagctca tacgcaggca ctagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001917             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:16267:4503
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001917
VERSION     KCVO01001917.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:16267:4503"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73946.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       386..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           85 a          143 c          136 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactgcacag actctgtggt ctcctatgaa ttgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacagca
      181 ttggaagtag aagtgtgcag tggtaccagc agaagcctcc gcaggccctt ctactggtca
      241 tctatgctga taccgaacgg ccctcaggca tccctgagcg attctctggc tccaatttag
      301 ggaacaccgc caccctgacc atcagcggcg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatgtgt tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001918             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:8846:3666
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001918
VERSION     KCVO01001918.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:8846:3666"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73947.1"
                     /translation="DYYCYSSDSNADYWVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           93 a          142 c          126 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctccg gagaagcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggtt ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcatca gatagcaatg ctgattattg ggtgttcggc ggagggaccc ggctgaccgt
      421 cccaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001919             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:18735:11809
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001919
VERSION     KCVO01001919.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:18735:11809"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73948.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       398..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           88 a          148 c          134 g           96 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gtctcctatg agctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 ccttggagat aaatatctac actggtacca ccagaagcca gcgcaggccc ctgtgctggt
      241 catctactat gatagtgacc ggccctcatg gatccctgag cgattctctg ggtccaagtc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagta ataatgatca catctttttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001920             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:5911:6432
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001920
VERSION     KCVO01001920.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:5911:6432"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..391
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73949.1"
                     /translation="DYYCYSTDSSGNQHIF"
     J_segment       394..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           95 a          142 c          125 g          105 t
ORIGIN      
        1 acatgggggg ctgtgggctc aggaggcaga gctctgggtg tctcaccatg gcctggattc
       61 ctctcctact ccccctcctc actttctgca caggctctgc agcctcgtat gagctgacac
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgc tctggagatg
      181 cattgccaaa aaaatatgct tattggttcc agcagaagcc aggccagtcc cctgtgttga
      241 tcatctatga ggacaggaaa cgtccctctg ggatccctga gagattctct ggctccagct
      301 cagggacagt ggccaccttg actatcagtg gggcccaggt ggaggatgaa gctgactact
      361 actgttattc aacagatagc agtggtaatc agcacatctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01001921             462 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:21665:12259
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001921
VERSION     KCVO01001921.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:21665:12259"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..424
                     /note="immunoglobulin light chain variable region"
     V_region        100..424
     V_segment       100..387
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>396
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73950.1"
                     /translation="DYYCQVWDSITDHSIF"
     J_segment       390..424
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>462
                     /gene="IGLC"
BASE COUNT           85 a          148 c          131 g           98 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctta ctgcacagtc tctgcggtct cctatgagct gactcagcca
      121 ccctcggtgt cagtgtcccc aggacagacg gccaggatca cctgtggggg ggacaacatt
      181 ggaactgaat atgtgcactg gtaccagcag aagccaccgc aggcccctgt ggtggtcatc
      241 tattataata ctgaccggcc ctcagggatc cctgagcgat tctcaggctc caaatcaggg
      301 aacaccggca ccctgaccat cagcggggtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtattac tgatcattcc atcttcggtg ctgggacccg gctcaccgtc
      421 ctaggtcagc ccaaggcttc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001922             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:12418:8120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001922
VERSION     KCVO01001922.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:12418:8120"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73951.1"
                     /translation="DYYCSSTDTSGNHVF"
     J_segment       390..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           91 a          143 c          125 g          102 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccagaaaa atttgcttat tggttccagc agaagtcagg ccagtcccct gtgttgatca
      241 tcaatgagga cagcaaacgg ccctctggga tccctgagag attctctggc tccagctcag
      301 ggacagtggc caccttgact ctcagtgggg cccaggtgga ggatgaagct gactactact
      361 gttcctcaac agataccagt ggtaatcatg tattcggcgg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001923             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:24976:8837
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001923
VERSION     KCVO01001923.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:24976:8837"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73952.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       393..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           94 a          141 c          124 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gcaaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaagac gacaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaata gatagtagtg gtagtcatag cgtcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001924             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:16687:11594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001924
VERSION     KCVO01001924.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16687:11594"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..442
                     /note="immunoglobulin light chain variable region"
     V_region        112..442
     V_segment       112..403
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73953.1"
                     /translation="DYYCQSYDSSLSVVLF"
     J_segment       406..442
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           91 a          154 c          126 g          109 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctcctc tcctcctcac ccttctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacgcagc cgccctcaat gtctggggcg cccgggcagg gggtcaccat ctcctgcact
      181 gggagcagct ccaacattgg agattattat gtgcagtggt accagcagtt tccaggaacg
      241 gcccccagac tcctcatcta tgaaaataat aaacgaccct caggggtttc tgatcgattc
      301 tctggctccc agtctgatac ctcagcctcc ctgaccatca ctggactcca gtctgaggat
      361 gaggctgatt attactgcca gtcctatgac agcagcctga gtgtcgtgtt attcggagga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001925             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:18986:10806
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001925
VERSION     KCVO01001925.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:18986:10806"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73954.1"
                     /translation="EYYCQSYDSKLSGHVF"
     J_segment       413..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           85 a          157 c          130 g          111 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctggcgc agccgccctc agtgtctggg gcgcccgggc agagggtcac cgtctcctgc
      181 actgggagca gctccaactt tggaggttat tatgtgcagt ggtaccagca gcttccagga
      241 acggccccca aactcctcat ctttgaaaat aataagcgcc cctcaggggt ttctgaccga
      301 ttctttggct cccagtctgg ctcctccgcc tccctgacca tcactggact ccagtctgag
      361 gatgaggctg aatattactg ccagtcctat gacagcaagt tgagtggtca tgtattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01001926             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:23060:8978
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001926
VERSION     KCVO01001926.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:23060:8978"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..258
                     /note="immunoglobulin light chain variable region"
     V_region        8..258
     V_segment       8..218
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <180..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73955.1"
                     /translation="EYHCFSTDSSGNHRGLF"
     J_segment       222..258
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        259..>296
                     /gene="IGLC"
BASE COUNT           65 a           82 c           81 g           68 t
ORIGIN      
        1 acatgggatt gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg
       61 tgttgatcat ctatgacgac agcaaacggc cctctgggat ccctgagaga ttctctggct
      121 ccagctcagg gacagtggcc accttgacta tcattggggc ccaggtggag gatgaagctg
      181 agtaccactg tttctcaaca gatagtagtg gtaatcatag gggcttattc ggaggaggga
      241 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001927             381 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:14531:5829
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001927
VERSION     KCVO01001927.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 381)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14531:5829"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    13..336
                     /note="immunoglobulin light chain variable region"
     V_region        13..336
     V_segment       13..308
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <271..>315
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73956.1"
                     /translation="DYFCCSYADTYTFVF"
     J_segment       313..336
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        337..>381
                     /gene="IGLC"
BASE COUNT           70 a          120 c           97 g           94 t
ORIGIN      
        1 acatgggggg ctcaggctgc cctgactcag cctcgctcag tgtctgggtc tcctggacag
       61 tcggtcacca tctcctgcac tggaaccagc agtgacatcg gtggttataa ctttgtctcc
      121 tggtaccaac aacatccagg cacagccccc aaactcatga tttatgaggt caatcagcgg
      181 ccctcagggg tctctgatcg cttctctggc tcaaagtctg gcaacacggc ctccctgacc
      241 gtctccgggg tccaggctga ggacgaggct gattatttct gctgctcata tgcagacacc
      301 tacacttttg ttttcggaag tggcaccagg ttgaccgtcg tcggtcagcc caaggcttcc
      361 cccttggtca ctctgttccc g
//
LOCUS       KCVO01001928             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:18722:13302
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001928
VERSION     KCVO01001928.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18722:13302"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73957.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           85 a          155 c          124 g          109 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca gtagcacttg ggttttcggc ggagggaccc
      421 ggctgaccgt ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001929             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:12598:19712
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001929
VERSION     KCVO01001929.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:12598:19712"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..368
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73958.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           96 a          142 c          113 g           95 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggta ccagcagaaa ccaggccagt cccctatgct gatcatctat gaggacaaca
      241 aacggccctc tgggatccct gaaagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcac tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 acagtggtca gggctcattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001930             387 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:26876:14486
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001930
VERSION     KCVO01001930.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 387)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:26876:14486"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    19..349
                     /note="immunoglobulin light chain variable region"
     V_region        19..349
     V_segment       19..312
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <274..>321
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73959.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       313..349
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        350..>387
                     /gene="IGLC"
BASE COUNT           77 a          126 c           98 g           86 t
ORIGIN      
        1 acatgggggt cctgggccca gtctgtgctg actcagcctc cctcagcgtc tgaggccgcc
       61 aggaagagtg tcaccatctc ctgttctgga agcacctcca acatcggaac taatagtgta
      121 tcctggtacc agcagctccc agaaacggct cccaaactcc tcatctatta taatgatcga
      181 cgagcctcag gtgtctctga ccgattctct ggctccaagt ctggcacgtc agcctccctg
      241 gccatcagtg ggctccagac cgaggatgag gctgattatt actgcgcagc atgggataac
      301 agcctgagcg gttacatctt cggtgctggg acccggctca ccgtcctagg tcagcccaag
      361 gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01001931             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:18342:11880
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001931
VERSION     KCVO01001931.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18342:11880"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73960.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       402..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           86 a          155 c          124 g          110 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catatacaag cagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001932             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:18735:14621
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001932
VERSION     KCVO01001932.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18735:14621"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..422
                     /note="immunoglobulin light chain variable region"
     V_region        99..422
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73961.1"
                     /translation="DYYCYSTDSSGHHRVF"
     J_segment       388..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>461
                     /gene="IGLC"
BASE COUNT           91 a          143 c          125 g          102 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 cagaaaaatt tgcttattgg ttccagcaga agccaggcca gtcccctgtg gtgatcatct
      241 atgaggacag caaacggccc tctgggatcc ctgagagatt ctctggctcc agctccggga
      301 cagtggccac cttgactatc agtggggccc aggtggagga tgaagctgac tactactgtt
      361 actcaacaga tagtagtggt catcataggg ttttcggcgg agggacccga ctgaccgtcc
      421 tacgtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001933             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:17701:17376
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001933
VERSION     KCVO01001933.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:17701:17376"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..427
                     /note="immunoglobulin light chain variable region"
     V_region        106..427
     V_segment       106..387
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73962.1"
                     /translation="DYHCQVWDSSSDVLF"
     J_segment       390..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           85 a          144 c          141 g           95 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgctcactgc acagactctg tggtctcctt tgaattgact
      121 cagccacgct cagtgtccgt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 agtattggaa gtagaagcgt gcagtggtac cagcagaagc caccgcaggc ccttgcactg
      241 gtcatctatg ctgatagcga acggccctca gggatccctg agcgcttctc tggctccaat
      301 ctagggaaca ccgccaccct gaccattagc ggcgtcgagg ccggggatga ggctgactat
      361 cactgtcagg tgtgggacag tagtagtgat gtgttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001934             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:18579:16578
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001934
VERSION     KCVO01001934.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:18579:16578"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73963.1"
                     /translation="DYYCYSSDSGADYWVF"
     J_segment       390..423
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>464
                     /gene="IGLC"
BASE COUNT           88 a          140 c          130 g          106 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccagaaaa atatgcttat tggttccagc agaagccagg ccagtcccct gtgttgatca
      241 tctatgagga cagcaaacgg ccctctggga tccctgagag attctctggt tccagctcag
      301 ggacagtggc caccttgtct atcagtgggg cccaggtgga ggatgaagct gactactact
      361 gttattcatc agatagcggt gctgattatt gggtgttcgg cggagggacc cggctgaccg
      421 tcccaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001935             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:4552:19817
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001935
VERSION     KCVO01001935.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:4552:19817"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..400
                     /gene="IGLV8-111"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73964.1"
                     /translation="DYYCTLYMGSGIYVF"
     J_segment       402..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           94 a          147 c          120 g          114 t
ORIGIN      
        1 acatggggga gaagcctgag agcacttggc cttcataagt gtccccacca tggcctggat
       61 gatgcttctc ctcggactcc ttgcttatgg ctcaggagtg gattctgaga ctgtggtgac
      121 ccaggagcca tcgttgtcag tgtcccctgg aggaacagtc acactctcct gtggcctgaa
      181 ctctggctca gtctctaccg ataactaccc cagctggtac cagcagaccc caggccaggc
      241 tccacgcatg gtcatctaca gcacaaacac tcgcccttct ggggtccctg atcgcttctc
      301 tggctccatc cttgcgaaca aagctgccct caccatcacg ggggctcagg cagacgatga
      361 atgtgattat tactgtacac tctacatggg tagtggcatt tatgtgttcg gaagtggcac
      421 caagttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01001936             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:21065:14143
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001936
VERSION     KCVO01001936.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21065:14143"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..447
                     /note="immunoglobulin light chain variable region"
     V_region        119..447
     V_segment       119..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73965.1"
                     /translation="DYYCQSYDSGLSGLLF"
     J_segment       416..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>487
                     /gene="IGLC"
BASE COUNT           88 a          155 c          129 g          115 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cttgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcaccatctc
      181 ctgcactggg agcagctcca acattggaga ttattatgtg cagtggtacc agcagcttcc
      241 aggaacggcc cccaaacttc tcatctatga aagttataag cgaccctcag gggtttctga
      301 tcgattctct ggctccccgt ctggtacctc agcctccctg accatcactg gactccagtc
      361 tgaggatgag gctgattatt actgccagtc ctatgacagc ggcctgagtg gtcttttatt
      421 cggaggaggg acccgactga tcgtcctggg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCVO01001937             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:19949:7111
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001937
VERSION     KCVO01001937.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:19949:7111"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73966.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           91 a          141 c          126 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggt cagtcccctg tgctgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagtagtg gtaattatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001938             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:14841:13222
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001938
VERSION     KCVO01001938.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:14841:13222"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..410
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73967.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       414..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          155 c          130 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggaccccgg gcagagggtc accatctcgt
      181 gcactgggag cagctccaac attggaggtt attttgtata ctggtaccat cagttcccag
      241 gaacagcccc caaactcctc atctatgaca ataataagcg accctcaggg atttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagcctg
      361 gggatgaggg tgattattac tgcggagcat gggatagcag cctgagtgct cgtttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001939             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:13197:5209
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001939
VERSION     KCVO01001939.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:13197:5209"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..429
                     /note="immunoglobulin light chain variable region"
     V_region        99..429
     V_segment       99..392
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73968.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       393..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           94 a          157 c          114 g          102 t
ORIGIN      
        1 acatggggac acagaaggca ggactcagga caatctccag catggcctgg ttccctctcc
       61 tcctcaccct cctcactcac tgtgcagggt cctgggccca gtctgtgctg actcagcctc
      121 cctcagcgtc tgaggccgcc aggaagagtg tcaccatctc ctgttctgga agcacctcca
      181 acatcggaac taatagtgta tcctggtacc agcagctccc agaaacggct cccaaactcc
      241 tcatctatta taatgatcga cgagcctcag gtgtctctga ccgattctct ggctccaagt
      301 ctggcacgtc agcctccctg gccatcagtg ggctccagac cgaggatgag gctgattatt
      361 actgcgcagc atgggataac agcctgagcg gttacatctt cggtgctggg acccggctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01001940             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:15900:14879
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001940
VERSION     KCVO01001940.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15900:14879"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73969.1"
                     /translation="DYYCQSGDSSANHYIF"
     J_segment       392..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT          101 a          137 c          124 g          104 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 gccaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggggaaat
      181 actggcaaaa aaatatgctc ggtggttcca gcagaagcca ggccaggccc ctgttctggt
      241 gatatataag gacactgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacatta gttaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactatta
      361 ctgtcaatca ggagacagca gtgctaatca ttacatcttc ggtgctggga cccggctcac
      421 cgtcctaggt cagcccaagg cttcccccac ggtcactctg ttcccg
//
LOCUS       KCVO01001941             439 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:10437:12294
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001941
VERSION     KCVO01001941.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10437:12294"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..401
                     /note="immunoglobulin light chain variable region"
     V_region        96..401
     V_segment       96..364
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <326..>373
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73970.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       369..401
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        402..>439
                     /gene="IGLC"
BASE COUNT           87 a          132 c          120 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcaccc tcggtgtcag tgtccccagg
      121 acagacggcc aggatcacct gctctggaga tgcattgcca aaaaagtatg cttattggtt
      181 ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaagacgaca aacggccctc
      241 tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct tgactatcag
      301 tggggcccag gtggaggatg aaggtgacta ctactgttac tcaatagaca gtagtggtag
      361 tcatagcgtc ttcggtgctg ggacccggct caccgtccta ggtcagccca aggcttcccc
      421 cacggtcact ctgttcccg
//
LOCUS       KCVO01001942             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:21384:19120
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001942
VERSION     KCVO01001942.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:21384:19120"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..429
                     /note="immunoglobulin light chain variable region"
     V_region        103..429
     V_segment       103..395
                     /gene="IGLV10-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73971.1"
                     /translation="DYYCSAWDSSLSAVLF"
     J_segment       397..429
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>471
                     /gene="IGLC"
BASE COUNT          104 a          160 c          125 g           82 t
ORIGIN      
        1 acatggggaa gcagagcttc ggcaagcaca gtgggaatcc gcaccatgcc ctgggctctg
       61 ctcctcctga ccctcctcac tcactctgca gtgccagtgg tccaggcagg gctgactcag
      121 ccaccctcag tgtccaaggg cttgagacag acggccacac tcacctgcac tggaaacagc
      181 aacaatgttg gcaaccaggg agcagcttgg ctgcagcagc accagggcca ccctcccaaa
      241 ctgctgtcct acaggaataa caaccggccc tccgggatct cagagagatt ctctgcatcc
      301 aggtcaggaa acacagcctc cctgaccatc accggactcc aacctgagga tgaggctgac
      361 tattactgct cagcatggga cagcagcctc agtgccgtgt tattcggagg ggggacccgg
      421 ctgaccgtcg taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001943             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:14510:4245
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001943
VERSION     KCVO01001943.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14510:4245"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..397
                     /gene="IGLV10-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <359..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73972.1"
                     /translation="DYYCSAWDSSLSAVLF"
     J_segment       398..434
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT          107 a          158 c          124 g           83 t
ORIGIN      
        1 acatggggaa agcagagctt cggcaagcac agtgggaatc cgcaccatgc cctgggctct
       61 gctcctcctg accctcctca ctcactctgc agtgccagtg gtccaggcag ggctgactca
      121 gccaccctca gtgtccaagg gcttgagaca gacggccaca ctcacctgca ctggaaacag
      181 caacaatgtt ggcaaccagg gagcaggttg gctgcagcag caccagggcc accctcccaa
      241 actgctgtcc tacaggaata acaaccggcc ctcgggaatc tcagagagat tctctgcatc
      301 caggtcagga aacacagcct ccctgaccat caccggactc caacctgagg atgaggctga
      361 ctattactgc tcagcatggg acagcagcct cagtgctgtg ttattcggag gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001944             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:12031:13472
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001944
VERSION     KCVO01001944.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:12031:13472"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73973.1"
                     /translation="DYYCSSYADTYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           79 a          161 c          119 g          113 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggcaccag
      181 cagtgacatc ggtggttata actttgtctc ctggtaccaa caccatccag gcacagcccc
      241 caaactcttg atttatgagg tcactcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcagcgcgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgctcctcat atgcagacac ttacactttt gtgttcggaa gtggcaccaa
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01001945             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:25946:5836
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001945
VERSION     KCVO01001945.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:25946:5836"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73974.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           97 a          143 c          122 g           98 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggtaccagca gaaaccaggc cagtccccta tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgaaaga ttctctggct ccagctcagg
      301 gacagtggcc accttgatta tcactggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacaacagtg gtcagggctc attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001946             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:13277:9983
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001946
VERSION     KCVO01001946.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:13277:9983"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73975.1"
                     /translation="EYYCSSYADIYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           85 a          160 c          118 g          109 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg cctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca cgggcaccag
      181 cagtgacatc ggtggttaca actttgtctc ctggtaccaa caccatccag acacagcccc
      241 caaactcgtg atttatgagg tcactcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacacgg cctccctgac catttctggg ctccaggctg aggacgaggc
      361 tgaatattac tgcagttcat atgcagacat ctacacattt gtgttcggaa gtggcaccaa
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01001947             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:22502:9508
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001947
VERSION     KCVO01001947.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:22502:9508"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73976.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          158 c          127 g          109 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaggtt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaactcctc atatatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggtacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cctgagtgcc gtgttattcg
      421 gagcagggac ccggctgacc gtcctaggtc aacccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01001948             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:13238:11242
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001948
VERSION     KCVO01001948.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:13238:11242"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73977.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       386..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           86 a          142 c          137 g           96 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactgcacag actctgtggt ctcctatgaa ttgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggagacagca
      181 ttggaagtag aagtgtgcag tggtaccagc agaagccacc gcaggccctt ctactggtca
      241 tctatgctga taccgaacgg ccctcaggga tccctgagcg attctctggc tccaatttag
      301 ggaacaccgc caccctgacc atcagcggcg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatgtgt tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001949             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:20915:6612
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001949
VERSION     KCVO01001949.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:20915:6612"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..449
                     /note="immunoglobulin light chain variable region"
     V_region        121..449
     V_segment       121..412
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73978.1"
                     /translation="DYYCQSFDTTLRAWVF"
     J_segment       413..449
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           91 a          159 c          130 g          107 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggcccg
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggcgccc gggcagaggg tcaccatcgc
      181 ctgcactggg agcagctcca acattggagg tcactatgtg cagtggtacc atcagctctc
      241 aggaacggcc cccaaactcc tcatatatga aaataataag cgaccctcag gggtttctga
      301 tcgattctct ggctcccagt ctggaacctc agcctccctg accatcactg gactccagtc
      361 tgaggatgag gctgattatt actgccagtc ctttgacacc acattgaggg cttgggtatt
      421 cggcggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCVO01001950             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:13002:8723
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001950
VERSION     KCVO01001950.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:13002:8723"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73979.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          161 c          124 g          108 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctac tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catatactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtactggagt gttgttcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01001951             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:16781:10780
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001951
VERSION     KCVO01001951.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16781:10780"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73980.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           95 a          144 c          123 g           99 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc catcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcgtt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccagacaa atatgcttat tggtaccggc agaaaccagg ccagtcccct atactgatca
      241 tctatgagga cagcaaacgg ccctctggga tccctgaaag attctctggc tccagttcag
      301 ggacagtggc caccttgact atcactgggg cccaggtgga ggatgaagct gactactact
      361 gttactctgc agacaacagt ggtcagggct cattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001952             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:8559:9631
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001952
VERSION     KCVO01001952.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8559:9631"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73981.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           87 a          139 c          140 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagattctgt agtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcattggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttgtactgg
      241 tcatctatgc tgatagggaa cggccctcag gtatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttgttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001953             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:12421:14514
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001953
VERSION     KCVO01001953.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:12421:14514"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73982.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           87 a          154 c          122 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa caacacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagtacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001954             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:20619:11054
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001954
VERSION     KCVO01001954.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:20619:11054"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..428
                     /note="immunoglobulin light chain variable region"
     V_region        106..428
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73983.1"
                     /translation="DYYCQVWDSSSSHYIF"
     J_segment       394..428
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>468
                     /gene="IGLC"
BASE COUNT           87 a          147 c          133 g          101 t
ORIGIN      
        1 acatggggga gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acagactctg cggtctccta tgacctgact
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg tggggaagac
      181 aaccttggaa gtgaatatgt gcactggtac cagcagaagc cagcgcaggc ccctgtagtg
      241 gtcatctatt ttgatagtga ccggccctca gggatccctg agcgattctc tggctccaaa
      301 tcagggaaca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag tagtagttct cattacattt tcgattctgg gacccggctc
      421 accgtcctgg gtcagcccaa ggcttccccc acggtcactc tgttcccg
//
LOCUS       KCVO01001955             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:17310:10602
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001955
VERSION     KCVO01001955.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:17310:10602"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73984.1"
                     /translation="DYYCQVWDSNSQYYIF"
     J_segment       392..429
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           92 a          151 c          129 g           95 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca caggctctgc ggcctcctat gagctgactc
      121 agccaccctc ggtgtcggtg tccccaggac agacagccag gatcacctgt gggggagaca
      181 acattggagg taaaagtgta cattggtacc aacagaagcc accgcaggcc cctgtactgg
      241 tcatatatac taatgccgaa cggccctcag ggatccctgc gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accatcaccg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt aatagtcagt attacatctt cggtgctggg acccgcctca
      421 ccgtcctagg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01001956             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:23541:7638
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001956
VERSION     KCVO01001956.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:23541:7638"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73985.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       390..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           94 a          145 c          124 g          101 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctctgac ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccaaaata ctatgcttat tggttccagc agaagccagg ccagtcccct gtggcgatca
      241 tctatgagga caacaaacgg ccctctggga tccctgagag attctctggc tccagctcag
      301 ggacagtggc caccttgact atcagtgggg cccaggtaga ggatgaagct gactactact
      361 gttactcaac agatagcagt ggtactaatg gcttattcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001957             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:21549:10770
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001957
VERSION     KCVO01001957.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:21549:10770"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73986.1"
                     /translation="DYFCAAWDDSLSSPLF"
     J_segment       393..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           88 a          155 c          115 g          107 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaac
      181 attggaagta attatgttac ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 atctatttta gtaatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgacgc tgattatttc
      361 tgtgcagcat gggatgacag cctgagcagt cccttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001958             447 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:14420:7805
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001958
VERSION     KCVO01001958.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:14420:7805"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    79..409
                     /note="immunoglobulin light chain variable region"
     V_region        79..409
     V_segment       79..369
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <334..>381
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73987.1"
                     /translation="DFYCQSYDSSLSIVLF"
     J_segment       372..409
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        410..>447
                     /gene="IGLC"
BASE COUNT           86 a          146 c          108 g          107 t
ORIGIN      
        1 acatggggga cagtctccag catggcctcg tctcctctcc tcctcaccct tctcattcac
       61 tgcacagggt cctgggccca gtctgttctg acacagccgc cctcagtgtc tggggcccca
      121 gggcagaggg tcaccatctc ctgcactggg agcagctcca acattggagg ttattatgta
      181 ttctggtacc aacaactccc aggaatggcc cccaaactcc tcatctatga caataataag
      241 cgaccctcag gggtttctga ccgattctct ggctccaagt ctggtacctc agcctccctg
      301 accatcactg ggctccagac tgaggatgag gctgattttt actgtcagtc ctatgacagc
      361 agcctgagta ttgtgttatt cggaggaggg acccggctga ccgtcctagg tcagcccaag
      421 gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001959             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:19898:16862
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001959
VERSION     KCVO01001959.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:19898:16862"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    110..455
                     /note="immunoglobulin light chain variable region"
     V_region        110..455
     V_segment       110..416
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <386..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73988.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       419..455
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        456..>493
                     /gene="IGLC"
BASE COUNT           91 a          166 c          126 g          110 t
ORIGIN      
        1 acatggggag cccaaccctg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct
       61 gactcctctc ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct
      121 gactcagcca ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct
      181 gagcagtgac ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag
      241 cgctcccagg ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt
      301 ccccaatcga gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc
      361 tgggctccag cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtactggagt
      421 gttgttcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg tcccctcggt
      481 cactctcttc ccg
//
LOCUS       KCVO01001960             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:17062:13115
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001960
VERSION     KCVO01001960.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:17062:13115"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..406
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73989.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           91 a          155 c          128 g          107 t
ORIGIN      
        1 acatggggag cttcagctgt gggtacagaa ggcaggactc aggacaatct ccagcatggc
       61 ctggttccct ctcctcctca ccctcctcac tcactgtgca gggtcctggg cccagtctgt
      121 gctgactcag cctccctcag cgtctgaggc cgccaggaag agtgtcacca tctcctgttc
      181 tggaagcacc tccaacatcg ggagtaacag tgtgtcctgg tacctgcagc tcccagaaac
      241 ggctcccaaa ctcctcatct attataatga tcggcgagcc tcaggtgtct ctgaccgatt
      301 ctctggctcc aagtctggcc cgtcagcctc cctggccatc agtgggctcg agaccgaaga
      361 tgaggctgat tattactgcg cagtatggga tgacagcctg agcggtgtgt tattcggagg
      421 agggacccga ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01001961             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1105:21632:18383
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001961
VERSION     KCVO01001961.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1105:21632:18383"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73990.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           87 a          155 c          122 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtaatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001962             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:6207:10002
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001962
VERSION     KCVO01001962.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:6207:10002"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73991.1"
                     /translation="DYYCAAWDDSLNSPFF"
     J_segment       418..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           94 a          162 c          120 g          110 t
ORIGIN      
        1 acatggggag ctcaccttca gctgcgggta cagaaggcag gactcaggat aatctccagc
       61 atggcctggt tccctctcgt cctcaccctc ctcactcact gtgcagggtc ctgggcccag
      121 tctgtgctga ctcagccacc ctcaacgtct ggggctcccg ggcagagtgt caccatctct
      181 tgctctggaa gcagctccaa cattggaagt aattatgtaa actggtacca gcaactccca
      241 ggaacggccc ccaaactcct catctatttt actaatcagc gaccctcagg ggtccctgac
      301 cgattctctg gctctaagtc tggcacctca gcctccctgg ccatcactgg tctccgatct
      361 gaggatgagg ctgattatta ctgtgcggca tgggatgaca gcctgaacag tcccttcttc
      421 ggaggaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01001963             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1108:11620:12067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001963
VERSION     KCVO01001963.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1108:11620:12067"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73992.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           93 a          140 c          125 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagca
      121 accctcggtg tcagtgtctc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactattg
      361 ttcctcaaca gatagcagtg gtaatcatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01001964             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:13435:15351
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001964
VERSION     KCVO01001964.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:13435:15351"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    91..436
                     /note="immunoglobulin light chain variable region"
     V_region        91..436
     V_segment       91..400
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73993.1"
                     /translation="DYHCMIRHNNAYIF"
     J_segment       401..436
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        437..>474
                     /gene="IGLC"
BASE COUNT           92 a          157 c          112 g          113 t
ORIGIN      
        1 atggggactg cggggaaaga ggctgtgtcc accatggcct ggactcctct cctcctcctg
       61 ctcctctctc actgcacagg ttccctctcg cagcctgtgc tgactcagcc aacctccctc
      121 tcagcatctc ctggaacatc agccagactc acctgcacct tgcgcagtgg catcagtgtt
      181 ggtggttacg ggattttctg gtaccaacag aagccaggga gtcctccccg gtatcttctg
      241 aactaccaca cagactcaga taagcaccag ggatctggag tccccagccg cttctctgga
      301 tccaaggata cttcggccaa tgcaggcttt ttactcatct ctgggctcca gtctgaggat
      361 gaggctgact atcactgtat gattcggcac aacaatgctt acatcttcgg tactgggacc
      421 cggctcaccg tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCVO01001965             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:23629:15828
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001965
VERSION     KCVO01001965.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:23629:15828"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..430
                     /note="immunoglobulin light chain variable region"
     V_region        103..430
     V_segment       103..395
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73994.1"
                     /translation="DYYCLLYCSGVHLF"
     J_segment       397..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           96 a          154 c          115 g          103 t
ORIGIN      
        1 acatggggtc tggagccaga gatcccttcc aataccagca ccatggcctg gactctgctc
       61 ctcctccagt tcctcctcac ttgctgccca gggtccaatt ctcaggctgt agtgactcag
      121 gagccctcaa tgactgtgtc cccaggaggg acagtcactc tcacctgtgg ctccagcact
      181 ggagcagtca ccagtagtaa ctttccaaac tggttccagc agaaacctgg acaagtcccc
      241 aggggactga tttacaatac acacaacaaa cactcctgga cccctgcccg gttctcaggc
      301 tccctcgctg gggccaaagc tgccctgaca ctgtcaggtg cacagcccga ggacgaggct
      361 gactattact gcttgctgta ttgtagtggt gttcatttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01001966             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:17099:3050
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001966
VERSION     KCVO01001966.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17099:3050"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73995.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       379..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           97 a          136 c          114 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acaaccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 tatattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaggacaaca
      241 aacggccctc tgggattcct gagagattct ctggctccag ctccgggaca gtggccacct
      301 tgactattag tggggcccag gtggaggatg aaggtgacta ctactgttac tcaagagata
      361 gtagtgaaaa tcaaagcgtc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001967             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:7947:15310
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001967
VERSION     KCVO01001967.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:7947:15310"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73996.1"
                     /translation="DYYCSSTDSSGNHVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           95 a          141 c          123 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 caatgaggac agcaaacggc cttctgggat ccctgagaga atctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtagag gatgaagctg actactactg
      361 ttcctcaaca gatagtagtg gtaatcatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcagtcac tctcttcccg
//
LOCUS       KCVO01001968             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:25295:14086
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001968
VERSION     KCVO01001968.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:25295:14086"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73997.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       397..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           90 a          142 c          139 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagactctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaaacc agcgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgtgtatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001969             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:15049:19706
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001969
VERSION     KCVO01001969.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:15049:19706"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73998.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           84 a          155 c          124 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggttattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg gtttatgagg tcagtaatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggctacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acgcaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc ctgggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001970             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:22565:10634
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001970
VERSION     KCVO01001970.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22565:10634"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV73999.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          161 c          125 g          108 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catatactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aagcagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcag gtgtatgaca gtactggagt gttgttcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01001971             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:7569:20894
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001971
VERSION     KCVO01001971.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7569:20894"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74000.1"
                     /translation="DYYCAAWDDSLNSPFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          155 c          115 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcggccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaac
      181 attggaagta attatgtaaa ctggtaccag caactcccag gaacggcccc caaactcctc
      241 atctatttta ctaatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcggcat gggatgacag cctgaacagt cccttcttcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001972             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:16169:12743
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001972
VERSION     KCVO01001972.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16169:12743"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74001.1"
                     /translation="DFYCYSRDSSENQSVF"
     J_segment       393..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           97 a          139 c          123 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaagaaaa tatgtatatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac aacaaacggc cctctgggat tcctgagaga ttctctggct ccacctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaaggtg acttctactg
      361 ttactcaaga gatagtagtg aaaatcaaag cgtcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001973             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:18390:7688
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001973
VERSION     KCVO01001973.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:18390:7688"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..388
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74002.1"
                     /translation="DYYCQSYDSSFSGLLF"
     J_segment       394..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           94 a          148 c          114 g          109 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagggtct tgggcccagt ctgtgctgac gcagccgccc
      121 tcaatatctg gggcgcccgg gcagagggtc accatctcct gcactgggag cagctccaac
      181 attggagatt attatgtgca gtggtaccag caacttccag gaacggcccc caaacttctc
      241 atctatgaaa ataataagcg accctcaggg gtttctgatc gattctctgg ctcccagtct
      301 ggtacctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgattattac
      361 tgccagtcct atgacagcag tttcagtggt cttttattcg gagaagggac ccgactgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001974             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:17830:12324
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001974
VERSION     KCVO01001974.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17830:12324"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74003.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           87 a          154 c          123 g          109 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagtaccca ggcaaagccc
      241 ccaaagtcat catttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttcactg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca gtagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01001975             286 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:12669:19550
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001975
VERSION     KCVO01001975.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 286)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:12669:19550"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    4..246
                     /note="immunoglobulin light chain variable region"
     V_region        4..246
     V_segment       4..212
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <176..>220
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74004.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       213..246
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        247..>286
                     /gene="IGLC"
BASE COUNT           57 a           90 c           74 g           65 t
ORIGIN      
        1 acatggggat tataaccgtg tctcctggta ccaacagcac ccaggcaaag cccccaaact
       61 catgatttat gaggtcagtg atcggccctc aggggtctct gatcgcttct ctggttccaa
      121 gtctggcaac acggcctccc tgatcatctc tgggctccag gctgaggacg aggctgatta
      181 ttactgcagc tcatacacaa gcagtagcac ttgggtattc ggcggaggga cccggctgac
      241 cgtccttggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001976             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:15421:20675
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001976
VERSION     KCVO01001976.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:15421:20675"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74005.1"
                     /translation="DYYCYSTDSSGNQHIF"
     J_segment       390..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           95 a          141 c          124 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcgtatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac aggaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttattcaaca gatagcagtg gtaatcagca catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001977             306 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:11607:9354
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001977
VERSION     KCVO01001977.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 306)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 306)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11607:9354"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    143..268
                     /note="immunoglobulin light chain variable region"
     V_region        143..268
     V_segment       143..231
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <193..>240
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74006.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       236..268
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        269..>306
                     /gene="IGLC"
BASE COUNT           54 a           98 c           83 g           71 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagtg gccaccttga ctatcagtgg ggcccaggtg
      181 gaggatgaag ctgactacta ctgttactca atagatagta gtggtagtca tagcgtcttc
      241 ggtgctggga cccggctcac cgtcctaggt cagcccaagg cttcccccac ggtcactctg
      301 ttcccg
//
LOCUS       KCVO01001978             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:13429:9906
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001978
VERSION     KCVO01001978.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:13429:9906"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74007.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           89 a          157 c          130 g          110 t
ORIGIN      
        1 acatgggggg ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcactggga gcagttccaa cattggaggt tattatgtgc agtggtacca gcagcttcca
      241 ggaacggccc ccaaactcct catgtatgaa aataataagc gaccctcagg ggtttctgat
      301 cgattctctg gctcccagtc tggtacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gcctgagtgc cgtgttattc
      421 ggagcaggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01001979             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:21265:5285
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001979
VERSION     KCVO01001979.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:21265:5285"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74008.1"
                     /translation="DYYCYSIDGSGNQSIF"
     J_segment       377..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           92 a          139 c          115 g          103 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acaaccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctgggga tgcattgcca aaaaaatttg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaggacagta
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aatctgacta ctactgttac tcaatagatg
      361 gcagtggaaa tcagagcatc ttcggtgctg ggacccggct caccgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001980             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:11265:3594
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001980
VERSION     KCVO01001980.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:11265:3594"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74009.1"
                     /translation="DYYCQSGDSSANHYIF"
     J_segment       389..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT          103 a          137 c          122 g          101 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgaggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 ggcaaaaaaa tatgctcggt ggttccagca gaagccaggc caggcccctg tgctggtgat
      241 atataaagac actgagaggc cctcagggat ccctgagcga ttctctagct ccagttcagg
      301 gacaatactt accttgacca tcagtggggc ccaggcagaa gatgaggctg actattactg
      361 tcaatcaggg gacagcagtg ctaatcatta catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001981             329 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:23319:4613
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001981
VERSION     KCVO01001981.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 329)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:23319:4613"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..291
                     /note="immunoglobulin light chain variable region"
     V_region        8..291
     V_segment       8..253
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <216..>263
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74010.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       259..291
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        292..>329
                     /gene="IGLC"
BASE COUNT           81 a           87 c           90 g           71 t
ORIGIN      
        1 acatgggagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
       61 tatattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaggacaaca
      121 aacggccctc tgggattcct gagagattct ctggctccag ctcagggaca gtggccacct
      181 tgactatcag tggggcccag gtagaggatg aaggtgacta ctactgttac tcaagagata
      241 gtagtgaaaa tcaaagcgtc ttcggtgctg ggacccggct cagcgtccta ggtcagccca
      301 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01001982             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:11091:10217
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001982
VERSION     KCVO01001982.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11091:10217"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74011.1"
                     /translation="DYHCFSTDSSGNHRGIF"
     J_segment       382..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           92 a          143 c          118 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatttg
      181 cttcttggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gacgacagca
      241 aacggccctc tgggatccct gagagagtct ctggctccag ctcagggaca gtggccacct
      301 tgactatcat tggggcccag gtggaggatg aagctgacta ccactgtttc tcaacagata
      361 gcagtggtaa tcataggggc atattcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01001983             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:9120:6096
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001983
VERSION     KCVO01001983.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:9120:6096"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74012.1"
                     /translation="DYFCQVWDSTNKYVLF"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           91 a          144 c          134 g           98 t
ORIGIN      
        1 acatggggag cctgactttg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca caggttttgt ggcctcctat gagctgactc
      121 agccaccctc ggtgtcggtg tccccaggac agacagccag gatcacctgt gggggagaca
      181 acattggaca tgaaagtgtg cactggtacc aacagaagcc accgcaggcc cctgtgttgg
      241 tcatatattc tggtggcgaa cggccctcag ggatccctga gcgattctct gccaccatgt
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 tctgtcaggt ctgggacagt actaataaat acgtattatt cggaggaggg acccgactga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001984             312 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:4125:13878
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001984
VERSION     KCVO01001984.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 312)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 312)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:4125:13878"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..274
                     /note="immunoglobulin light chain variable region"
     V_region        8..274
     V_segment       8..234
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <202..>246
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74013.1"
                     /translation="DYYCQVWDSGSDVLF"
     J_segment       237..274
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        275..>312
                     /gene="IGLC"
BASE COUNT           61 a           82 c          103 g           66 t
ORIGIN      
        1 acatggggga tcacctgtgg gggagacagt attggaagta ggagtgtgca gtggtaccag
       61 cagaagccac cgcaggccct tgtgctggtc atgtatgctg atagcgaacg gccctcaggg
      121 atccctgagc gattttctgg ctccaattta gggaacaccg ccaccctgac catcagcggc
      181 gtcgaggccg gggatgaggc tgactattac tgtcaggtgt gggacagtgg tagtgatgtg
      241 ttattcggag gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc
      301 actctcttcc cg
//
LOCUS       KCVO01001985             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:9019:10422
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001985
VERSION     KCVO01001985.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:9019:10422"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74014.1"
                     /translation="DYYCQVWDSSSDVFF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           85 a          142 c          141 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gagttgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcattggaag tagaagtgtg cagtggtacc aggagaagcc accgcaggcc cttgtactgg
      241 tcatctatgc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 taggcaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttcttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001986             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:9095:2570
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001986
VERSION     KCVO01001986.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:9095:2570"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..425
                     /note="immunoglobulin light chain variable region"
     V_region        104..425
     V_segment       104..391
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74015.1"
                     /translation="DYYCQVWDSSSKYIF"
     J_segment       392..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          149 c          132 g           94 t
ORIGIN      
        1 acatgggggc ctgactttgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg ctcactgcac aggctctgcg gcctcctatg acctgactca
      121 gccaccctcg gtgtcggtgt ccccaggaca gacagccagg atcacctgtg ggggagacaa
      181 cattggaagt aaaagtgtgc actggtacca ccagaggcca ccgcaggccc ctgtcctggt
      241 catatatact gatagcgaac ggccctcagg gatccctgac cgattctctg gctccaactc
      301 agggaatacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgattatta
      361 ctgtcaggtg tgggacagta gtagtaagta catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001987             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:19835:14194
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001987
VERSION     KCVO01001987.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:19835:14194"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74016.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          144 c          125 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgacgac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcattggggc ccaggtggag gatgaagctg actaccactg
      361 tttctcaaca gatagtagtg gtaatcatag gggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001988             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:8787:10964
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001988
VERSION     KCVO01001988.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:8787:10964"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74017.1"
                     /translation="DYYCQVWDSSSDHVLF"
     J_segment       395..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          142 c          140 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagttgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaga tgaatatgta cactggtacc agcagaagcc agcgcgggcc cctgtgttgg
      241 tcatctatta cgatagtgac cggccctcat ggatccctga gcgattctct gggtccaaat
      301 cagggaaaac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc atgtcttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01001989             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:25619:8964
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001989
VERSION     KCVO01001989.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:25619:8964"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74018.1"
                     /translation="DYYCAAWDDSLNSPFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           92 a          155 c          113 g          105 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg gcagagtgtc accatctctt gctctggaag cagctccaac
      181 attggaagta attatgtaaa ctggtaccag caactcccag gaacggcccc caaactcctc
      241 atctatttta ctaatcagcg accctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcggcat gggatgacag cctgaacagt cccttcttcg gaggagggac ccgactgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01001990             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:6558:4653
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001990
VERSION     KCVO01001990.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:6558:4653"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..383
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74019.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       391..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          142 c          126 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctttg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tactgttcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccagggggag gatgaagctg actactactg
      361 ttattcaatg gatagcagtg gtacgcagag catcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001991             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:11505:19820
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001991
VERSION     KCVO01001991.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:11505:19820"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74020.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           96 a          144 c          124 g           97 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc catcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcgtt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccagaaaa atatgcttat tggtaccagc agaaaccagg ccagtcccct atgctgatca
      241 tctgtgagga cagcaaacgg ccctctggga tccctgaaag attctctggc tccagctcag
      301 ggacagtggc caccttgact atcactgggg cccaggtgga ggatgaagct gactactact
      361 gttactcagc agacaacagt ggtcagggct cattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001992             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:12881:14592
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001992
VERSION     KCVO01001992.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12881:14592"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74021.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          143 c          127 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc tcctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaaggcaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctgtggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gataacagtg atactcatag gggcttcttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001993             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:5361:13919
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001993
VERSION     KCVO01001993.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:5361:13919"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74022.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       393..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           99 a          140 c          121 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctacagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgtatatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctctgaggac aacaaacggc cctctgggat tcctgagaca ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaaggtg actactactg
      361 ttactcaaga gatagtagtg aaaatcaaag cgtcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01001994             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:20359:10581
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001994
VERSION     KCVO01001994.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:20359:10581"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..407
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74023.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       409..444
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           90 a          155 c          130 g          107 t
ORIGIN      
        1 acatggggct gcttcagctg tgggcacagg aggcagcact caggacagtc tccagcatgg
       61 cctggtctcc tctcctcctc acccttctca ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gtgtctgggg accccgggca gagggtcacc atctcgtgca
      181 ctgggagcag gtccaacatt ggaggttatt ttgtatactg gtaccagcag ttcccaggaa
      241 cagcccccaa actcctcatc tatgacaata ataagcgacc ctcagggatt tctgaccgat
      301 tctctggctc caagtctggt acctcagcct ccctgaccat cactgggctc cagcctgggg
      361 atgaggctga ttattactgc ggagcatggg atagcagcct gagtgctcgc ttattcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01001995             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:14691:8094
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001995
VERSION     KCVO01001995.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:14691:8094"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..406
                     /note="immunoglobulin light chain variable region"
     V_region        87..406
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74024.1"
                     /translation="DYYCHSLDTSGNDVF"
     J_segment       378..406
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        407..>446
                     /gene="IGLC"
BASE COUNT           88 a          141 c          118 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcactgcca aaaaaatttg
      181 cttactggtt ccagcagaag ccaggccagt cccctgtggc gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgtcat tcattagata
      361 ccagtggtaa tgatgttttc ggcggaggga cccggctgac cgtcctgggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01001996             474 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:7615:3427
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001996
VERSION     KCVO01001996.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 474)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:7615:3427"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..429
                     /note="immunoglobulin light chain variable region"
     V_region        106..429
     V_segment       106..401
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <364..>408
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74025.1"
                     /translation="DYFCCSYADTYTFVF"
     J_segment       406..429
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>474
                     /gene="IGLC"
BASE COUNT           83 a          156 c          123 g          112 t
ORIGIN      
        1 acatgggggg ggggtctcag acggcagcgc tctcgggaca tctccaccat ggcctgggct
       61 ctgctcctcc tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact
      121 cagcctcgct cagtgtctgg gtctcctgga cagtcggtca ccatctcctg cactggaacc
      181 agcagtgaca tcggtggtta taactttgtc tcctggtacc aacaacatcc aggcacagcc
      241 cccaaactca tgatttatga ggtcaatcag cggccctcag gggtctctga tcgcttctct
      301 ggctcaaagt ctggcaacac ggcctccctg accgtctccg gggtccaggc tgaggacgag
      361 gctgattatt tctgctgctc atatgcagac acctacactt ttgttttcgg aagtggcacc
      421 aggttgaccg tcgtcggtca gcccaaggct tcccccttgg tcactctgtt cccg
//
LOCUS       KCVO01001997             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:10022:15976
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001997
VERSION     KCVO01001997.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:10022:15976"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74026.1"
                     /translation="DYYCQVWDSSSDVFF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           86 a          142 c          139 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 ccattggaag tagaagtgtg cagtggtatc agcagaagcc accgcaggcc cttgtactgg
      241 tcatctatgc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttcttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01001998             511 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:16815:21984
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001998
VERSION     KCVO01001998.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 511)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 511)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..511
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16815:21984"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    143..471
                     /note="immunoglobulin light chain variable region"
     V_region        143..471
     V_segment       143..437
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <401..>445
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74027.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       438..471
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        472..>511
                     /gene="IGLC"
BASE COUNT           94 a          161 c          142 g          114 t
ORIGIN      
        1 acatggggga gaggggataa gacagggctg ggggcaggtc cagtgctggg atctcaggag
       61 gcagcactct caggacgtct ccaccatggc ctgggctctg ctcctcctca ccctcctcac
      121 tcagggcaca ggatcctggg ctcaggctgc cctgactcag tctccctctg tgtctgggtc
      181 tcctggacag tcggtcacca tttcctgcac tggaaccagc agtgacattg gtgattataa
      241 ccgtgtctcc tggtaccaac agcacccagg caaagccccc aaactcatga tttatgaggt
      301 cagtgatcgg ccctcagggg tctctgatcg cttctctggt tccaagtctg gcaacacggc
      361 ctccctgatc atctctgggc tccaggctga ggacgaggct gattattact gcagctcata
      421 cactagcagt agcacttggg tattcggcgg agggacccgg ctgaccgtcc ttggtcagcc
      481 caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01001999             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:7274:3854
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01001999
VERSION     KCVO01001999.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:7274:3854"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74028.1"
                     /translation="DYYCYSTRGSGYHGLF"
     J_segment       375..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           89 a          140 c          116 g          104 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaggacacca
      241 aacggccctc tgggatctct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtgcaggatg aagctgacta ctactgttac tcaactcgtg
      361 gcagtggtta tcatggctta ttcggaggag ggacttggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01002000             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:3302:10283
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002000
VERSION     KCVO01002000.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:3302:10283"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..444
                     /note="immunoglobulin light chain variable region"
     V_region        114..444
     V_segment       114..405
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74029.1"
                     /translation="DYYCSAWDNSLSGYIF"
     J_segment       407..444
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          153 c          129 g          113 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tctccttctc actctgctgg ttcactgcac agggtcctgg gcccagtctg
      121 tgctgacgca gccgccctca gcatctgggg cccccgggca gagggtcacc atctcgtgca
      181 ctgggagcag ctccaacatt ggaggttatt ctgtatcctg gtaccggcaa cgcccaggag
      241 cggtccccaa actcctcatc tttgaaaata ataagcgacc ctcaggtgtc tctgaccgat
      301 tctctggctc caagtctggt gtctcagcct ccctatgcat cactggactc cagtctgagg
      361 atgaggctga ttattactgc tcagcttggg ataacagcct gagtggttac atcttcggtg
      421 ctgggacccg agtcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      481 cg
//
LOCUS       KCVO01002001             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:7406:12014
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002001
VERSION     KCVO01002001.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:7406:12014"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..411
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74030.1"
                     /translation="DYYCGVWDSSLSARLF"
     J_segment       413..448
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           90 a          157 c          130 g          109 t
ORIGIN      
        1 acatggggag ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggaccccg ggcagagggt caccatctcg
      181 tgcactggga gcagctccaa cattggaggt tattttgtat actggtacca gcagttccca
      241 ggaacagccc ccaaactcct catctatgac aataataagc gaccctcagg gatttctgac
      301 cgattctctg gctccaagtc tggtacctca gcctccctga ccatcactgg gctccagcct
      361 ggggatgagg ctgattatta ctgcggagta tgggatagca gcctgagtgc tcgcttattc
      421 ggaggcggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01002002             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:13387:10005
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002002
VERSION     KCVO01002002.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:13387:10005"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..424
                     /note="immunoglobulin light chain variable region"
     V_region        102..424
     V_segment       102..383
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74031.1"
                     /translation="DYYCQVWDSSSDHWVF"
     J_segment       389..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>464
                     /gene="IGLC"
BASE COUNT           85 a          142 c          140 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactgcacag actctgcggt ctcctatgag ctgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggcccggat cacctgtggg ggagacaaca
      181 ttggaagtaa aagtgtgcag tggttccagc aaaagccacc gcaggcccct gtgttggtca
      241 tttatggtga tagcgaacgg ccctcaggga tccctgagcg attctctggt tccaactcag
      301 ggaacattgc caccctgacc atcagcgggg tcgaggccgg gaatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatcatt gggtattcgg cggagggacc cggctgaccg
      421 tcctcggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01002003             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:18206:15508
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002003
VERSION     KCVO01002003.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18206:15508"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..442
                     /note="immunoglobulin light chain variable region"
     V_region        109..442
     V_segment       109..402
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74032.1"
                     /translation="DYYCSLWDSRLSSRLF"
     J_segment       410..442
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           93 a          154 c          125 g          108 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg
      121 acgcagccgc cctcagcatc tggggccccc gggcagaggg tcaccatctc ctgcactggg
      181 accagctcca acatcggggc gaattattat gtttcctggt accagcaatt cccaggaaca
      241 gcccccaaac tcctcatcta tgaaaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggtac ctcagcctcc ctgaccatct ctggactcca atctgaggat
      361 gaggctgatt attactgctc actatgggat agcaggctga gtagtcggtt attcggcgga
      421 gggacccgac tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01002004             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:8677:19857
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002004
VERSION     KCVO01002004.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:8677:19857"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74033.1"
                     /translation="DYYCSSTDTSGNHVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           92 a          144 c          125 g           99 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaaggtg actactactg
      361 ttcctcaaca gataccagtg gtaatcatgt attcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01002005             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:25315:10251
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002005
VERSION     KCVO01002005.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:25315:10251"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..447
                     /note="immunoglobulin light chain variable region"
     V_region        119..447
     V_segment       119..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74034.1"
                     /translation="DYYCQSFDTTLRAWVF"
     J_segment       411..447
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           89 a          159 c          130 g          107 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccggt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatcgcct
      181 gcactgggag cagctccaac attggaggtc actatgtgca gtggtaccat cagctctcag
      241 gaacggcccc caaactcctc atatatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggaacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct ttgacaccac attgagggct tgggtattcg
      421 gcggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01002006             494 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:14054:4379
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002006
VERSION     KCVO01002006.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 494)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:14054:4379"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    123..456
                     /note="immunoglobulin light chain variable region"
     V_region        123..456
     V_segment       123..414
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <378..>428
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74035.1"
                     /translation="IYYCLSYDTSLSGHGLF"
     J_segment       419..456
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        457..>494
                     /gene="IGLC"
BASE COUNT           94 a          165 c          125 g          110 t
ORIGIN      
        1 acatgggggg ggaagctctg cttcagctgt gggcacagga ggcagcactc aggacagtct
       61 ccaacatggc ctcgtctcct ctcctcctca cccttctcat tcactgcaca gggtcctggg
      121 cccagtctgt actgacacag ccaccctcac tgtctggggc cccagggcag agggtcacca
      181 tctcgtgcac tgggagcagc tccaacattg gaggttattc tatatcctgg tgccagaagt
      241 tcccagaaac gacccccaac ctcctcgact atcaagataa taagcgaccc tcaggggttt
      301 ctgaccgatt ctctggctcc aagtctggtc cctcagcctc cctgaccatc gctgggctcc
      361 agactgagga tgggcctatt tattactgcc tgtcgtatga caccagcctg agtggtcatg
      421 gcttattcgg aggaggaccc cggctgaccg tcctaggtca gcccaaggct gccccctcgg
      481 tcactctctt cccg
//
LOCUS       KCVO01002007             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:8078:10566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002007
VERSION     KCVO01002007.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:8078:10566"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74036.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           87 a          156 c          121 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgct catctctggg ctccagactg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagcacttgg gtattcggcg gagggacccg
      421 actgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01002008             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2103:17265:11684
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002008
VERSION     KCVO01002008.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2103:17265:11684"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..397
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74037.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       398..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           86 a          160 c          118 g          107 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcactct caggacgtct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 tctccctctg tgtctgggtc tcctggacag tcggtcacca tttcctgcac tggaaccagc
      181 agtgacattg gtggttataa ccgtgtctcc tggtaccaac agcacccagg caaagccccc
      241 aaactcatga tttatgacgt cagtgatcgg ccctcagggg tctctgatcg cttctctggt
      301 tccaagtctg gcaacacggc ctccctgatc atctctgggc tccaggctga ggacgaggct
      361 gattattact gcagctcata cacaagcact accacttggc tattcggcgg agggacccgc
      421 ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01002009             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:6631:12806
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002009
VERSION     KCVO01002009.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:6631:12806"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74038.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           82 a          151 c          127 g          113 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggtttt gagcgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactctt gatttatgag gtcagttatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ttgcagctca tacgcaagta gtagtacttg ggtattcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01002010             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:17679:14135
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002010
VERSION     KCVO01002010.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:17679:14135"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74039.1"
                     /translation="DYYCSSYTSSSSWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          155 c          125 g          108 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacacaag cagtagcagt tgggtattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01002011             342 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:17066:15572
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002011
VERSION     KCVO01002011.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 342)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:17066:15572"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..304
                     /note="immunoglobulin light chain variable region"
     V_region        7..304
     V_segment       7..266
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <229..>276
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74040.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       268..304
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        305..>342
                     /gene="IGLC"
BASE COUNT           69 a          105 c           91 g           77 t
ORIGIN      
        1 acatgggggg cgcccgggca gagggtcacc atctcctgca ctgggagcag ttccaacatt
       61 ggaggttatt atgtgcagtg gtaccagcag cttccaggaa cggcccccaa actcctcatg
      121 tatgaaaata ataagcgacc ctcaggggtt tctgatcgat tctctggctc ccagtctggt
      181 acctcagcct ccctgaccat cactggactc cagtctgagg atgaggctga ttattactgc
      241 cagtcctatg acagcagcct gagtgccgtg ttattcggag cagggacccg gctgaccgtc
      301 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01002012             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:18870:4239
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002012
VERSION     KCVO01002012.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18870:4239"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74041.1"
                     /translation="DYYCYSSESSADYWVF"
     J_segment       389..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>463
                     /gene="IGLC"
BASE COUNT           91 a          141 c          127 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgacgac agcaaacggc cctctgggat ccctgagaga ttctctggtt ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcatca gaaagtagtg ctgattattg ggtgttcggc ggagggaccc ggctgaccgt
      421 cccaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01002013             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:22811:12292
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002013
VERSION     KCVO01002013.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:22811:12292"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..433
                     /note="immunoglobulin light chain variable region"
     V_region        103..433
     V_segment       103..398
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74042.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       399..433
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>471
                     /gene="IGLC"
BASE COUNT           84 a          155 c          118 g          114 t
ORIGIN      
        1 acatgggggg gtctcagacg gcagcgctct cgggacatct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 cctcgctcag tgtctgggtc tcctggacag tcggtcacca tctcctgcac tggaaccagc
      181 agtgacatcg gtacttataa ctatgtctcc tggtaccaac agcatccagg cacagccccc
      241 aaactcatga tttttgaagt cagtgagcgg ccctcagggg tctctgatcg cttctctggc
      301 tccaagtctg gcaacacggc ctccctgacc atctctgggc ttcaggctga ggacgaggct
      361 gattattact gttgctcata tgcagacacc tacacttttg tgtttggagg tggcaccaga
      421 ttgaccgtcc tcggtcagcc caaggcttcc cccttggtca ctctgttccc g
//
LOCUS       KCVO01002014             452 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:19544:7133
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002014
VERSION     KCVO01002014.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19544:7133"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..414
                     /note="immunoglobulin light chain variable region"
     V_region        87..414
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>386
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74043.1"
                     /translation="DYYCYSTDNSDTHRGFF"
     J_segment       378..414
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        415..>452
                     /gene="IGLC"
BASE COUNT           92 a          141 c          117 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatctcct gctctggaga tgcattgcaa aaaaaatttg
      181 cttcttggtt ccagcagaag gcaggccagt cccctgtgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccag ttcagggaca gtggccacct
      301 tgactatcag tcgggcccag gtggaggatg aagctgacta ctactgttac tcaacagata
      361 acagtgatac tcataggggc ttcttcggag gagggacccg gctgaccgtc ctaggtcagc
      421 ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01002015             450 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:16455:4286
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002015
VERSION     KCVO01002015.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 450)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:16455:4286"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    82..412
                     /note="immunoglobulin light chain variable region"
     V_region        82..412
     V_segment       82..373
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <337..>384
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74044.1"
                     /translation="DYYCSAWDNSLSGYIF"
     J_segment       375..412
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        413..>450
                     /gene="IGLC"
BASE COUNT           82 a          144 c          117 g          107 t
ORIGIN      
        1 acatggggac tcaggacagt ctccagcatg gcctggtctc tccttctcac tctgctggtt
       61 cactgcacag ggtcctgggc ccagtctgtg ctgacgcagc cgccctcagc atctggggcc
      121 cccgggcaga gggtcaccat ctcgtgcact gggagcagct ccaacattgg aggttattct
      181 gtatcctggt accggcaacg cccaggagcg gtccccaaac tcctcatctt tgaaaataat
      241 aagcgaccct caggtgtctc tgaccgattc tctggctcca agtctggtgt ctcagcctcc
      301 ctatgcatca ctggactcca gtctgaggat gaggctgatt attactgctc agcttgggat
      361 aacagcctga gtggttacat cttcggtgct gggacccgag tcaccgtcct aggtcagccc
      421 aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01002016             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:21702:11374
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002016
VERSION     KCVO01002016.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:21702:11374"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74045.1"
                     /translation="DYYCQSFDSSLSAVFF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           88 a          159 c          127 g          111 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accctctcct
      181 gcactgggag cagctccaac attggaggtt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaactcctc atctatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggtacctcag cctccctgac catcactgga ctccagtctg
      361 aagatgaggc tgattattac tgccagtcct ttgacagcag cctgagtgcc gtgtttttcg
      421 gaggagggac ccggctaacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01002017             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:23019:3158
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002017
VERSION     KCVO01002017.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:23019:3158"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74046.1"
                     /translation="DYYCYSTDNTDTHRGFF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          143 c          124 g          106 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatgacct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc tcctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaaggcaggc cagtcccctg tgttgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggtt ccagttcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaacc gataacactg atactcatag gggcttcttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01002018             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:19316:10164
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002018
VERSION     KCVO01002018.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:19316:10164"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..431
                     /note="immunoglobulin light chain variable region"
     V_region        107..431
     V_segment       107..394
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74047.1"
                     /translation="DYYCQVWDSITDHSIF"
     J_segment       397..431
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           88 a          149 c          134 g           98 t
ORIGIN      
        1 acatggggga agcctggcct cgggaagcag ccttggcggt gcctcagcca tggccgggac
       61 ccttctcctc ctcggcctcc ttgcttactg cacagtctct gcggtctcct atgagctgac
      121 tcagccaccc tcggtgtcag tgtccccagg acagacggcc aggatcacct gtggggggga
      181 caacattgga actgaatatg tgcactggta ccagcagaag ccaccgcagg cccctgtggt
      241 ggtcatctat tataatactg accggccctc agggatccct gagcgattct caggctccaa
      301 atcagggaac accggcaccc tgaccatcag cggggtcgag gccggggatg aggctgacta
      361 ttactgtcag gtgtgggaca gtattactga tcattccatc ttcggtgctg ggacccggct
      421 caccgtccta ggtcagccca aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01002019             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:14463:9155
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002019
VERSION     KCVO01002019.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14463:9155"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74048.1"
                     /translation="DYYCCSYAGRFTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           80 a          157 c          122 g          113 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctgggaccag
      181 cagtgacatc ggtgattatg actttgtctc ctggtaccaa cagcatccag gcacagcccc
      241 caaactcata atttttgagg tcagtaagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctccaagtcc ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgacgc
      361 tgattattac tgctgctcat atgcaggcag gttcactttt gtgttcggaa gtggcaccag
      421 tttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01002020             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:27515:15979
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002020
VERSION     KCVO01002020.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:27515:15979"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..254
                     /note="immunoglobulin light chain variable region"
     V_region        8..254
     V_segment       8..217
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74049.1"
                     /translation="DYYCAAWDDSLSSPLF"
     J_segment       220..254
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>292
                     /gene="IGLC"
BASE COUNT           59 a           89 c           74 g           70 t
ORIGIN      
        1 acatgggatt ggaagtaatt atgtaaactg gtaccagcag ctcccaggaa cggcccccaa
       61 actcctcatc tattttagta atcagcggcc ctcaggggtc cctgaccgat tctctggctc
      121 taagtctggc acctcagcct ccctggccat cactggtctc cgatctgagg atgaggctga
      181 ttattactgt gcagcatggg atgatagtct gagcagtccc ttattcggag gagggacccg
      241 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01002021             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:7162:7322
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002021
VERSION     KCVO01002021.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:7162:7322"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74050.1"
                     /translation="DYYCYSIDISGNHRVF"
     J_segment       390..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          141 c          124 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctacgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgaggac aataaacggc cctctgggtt ccctgagcga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaata gatatcagtg gtaatcatag ggttttcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01002022             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:25457:5509
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002022
VERSION     KCVO01002022.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:25457:5509"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74051.1"
                     /translation="DYYCGVWDSSLSVRLF"
     J_segment       414..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          153 c          131 g          111 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggaccccgg gcagagggtc accatctcgt
      181 gcactgggag cagctccaac attggaggtt attttgtata ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atgtatgaca ataataagcg accctcaggg atttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagcctg
      361 gggatgaggc tgattattac tgcggagtat gggatagcag cctgagtgtt cgtttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01002023             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:20861:8694
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002023
VERSION     KCVO01002023.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20861:8694"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..289
                     /note="immunoglobulin light chain variable region"
     V_region        8..289
     V_segment       8..250
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <214..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74052.1"
                     /translation="DYYCQSYDSRLSGHVF"
     J_segment       257..289
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>327
                     /gene="IGLC"
BASE COUNT           64 a           98 c           86 g           79 t
ORIGIN      
        1 acatgggggg tcaccgtctc ctgcactggg agcagctcca actttggagg ttattatgtg
       61 cagtggtacc agcaacttcc aggaacggcc cccaaactcc tcatctatga aaataataag
      121 cgcccctcag gggtttctga tcgattctgt ggctcccagt ctggttcctc cgcctccctg
      181 accatcactg gactccagtc tgaggatgag gctgattatt actgccagtc ctatgacagc
      241 aggttgagtg gtcatgtatt cggaggaggg acccgggtga ccgtcctagg tcagcccaag
      301 gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01002024             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:16071:20473
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002024
VERSION     KCVO01002024.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:16071:20473"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..407
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74053.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           90 a          155 c          127 g          111 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc aatgtctggg gcgcccgggc agggggtcac catctcctgc
      181 actgggagca gctccaatat tggagattat tatgtgcagt ggtaccagca gtttccagga
      241 acggccccca gactcctcat ctatgaaaat aataaacgac cctcaggggt ttctgatcga
      301 ttctctggct cccagtctgg tacctcagcc tccctgacca tcactggact ccagtctgag
      361 gatgaggctg attattactg ccagtcctat gacagcagcc tgagtgccgt gttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01002025             424 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:18606:10349
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002025
VERSION     KCVO01002025.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 424)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:18606:10349"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    56..386
                     /note="immunoglobulin light chain variable region"
     V_region        56..386
     V_segment       56..350
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <314..>358
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74054.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       351..386
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        387..>424
                     /gene="IGLC"
BASE COUNT           81 a          139 c          110 g           94 t
ORIGIN      
        1 acatgggggt ccagggaagc agaagcctct gagcccaggc ccaggatcct gggctcaggc
       61 tgccctgact cagtctccct ctgtgtctgg gtctcctgga cagtcggtca ccatttcctg
      121 cactggaacc agcagtgaca ttggtggtta taaccgtgtc tcctggtacc aacagcaccc
      181 aggcaaagcc cccaaactca tgatttatga cgtcagtgat cggccctcag gggtctctga
      241 tcgcttctct ggttccaagt ctggcaacac ggcctccctg atcatctctg ggctccaggc
      301 tgaggacgag gctgattatt actgcagctc atacacaagc actaccactt ggctattcgg
      361 cggagggacc cgcctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      421 cccg
//
LOCUS       KCVO01002026             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:21308:6843
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002026
VERSION     KCVO01002026.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:21308:6843"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74055.1"
                     /translation="DYYCSSYAGTSTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           86 a          156 c          125 g          108 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accgtttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc ataatttatg aggtcagtaa tcggccctca ggggtctctg atcgcttctc
      301 tggttctaag tctggcaaca cggcctccct gagcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacgcagg cactagcact tgggtattcg gcggagggac
      421 ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01002027             563 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:14799:19367
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002027
VERSION     KCVO01002027.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 563)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 563)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..563
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:14799:19367"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    204..525
                     /note="immunoglobulin light chain variable region"
     V_region        204..525
     V_segment       204..491
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <453..>497
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74056.1"
                     /translation="DYYCQVWDSSSKYLF"
     J_segment       492..525
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        526..>563
                     /gene="IGLC"
BASE COUNT          115 a          178 c          157 g          113 t
ORIGIN      
        1 acatggggac agatctcctc cagcagcagc cgctgactct gctgatttgc atcatgggcc
       61 actctctcca gtaagaggat aagagaagcc tggaaggcac ctgccctgtc tgggtctcag
      121 gaggcagcat tgacggtgcc tcagccatgg cctggaccct tctcctcctc ggcctcctcg
      181 ctcactgcac aggctctgcg ccctcctatg agctgactca gccaccctcg gtgtcagcgg
      241 cctcaggaca gacggccagg atcacctgtg ggggagacaa cattggaagt aaaaatgtgc
      301 actggtatca gcagaagcca ccgcaggccc ctgtgctggt catctatgct gatagcaacc
      361 ggccctcagg gatccctgag cgattttctg gctccaactc agggaacacc gccaccctga
      421 ccatcagcag ggtcgaggcc ggggatgagg ctgactatta ctgtcaggtg tgggacagtt
      481 ctagtaaata cttattcgga ggagggaccc ggctgaccgt cctaggtcag cccaaggctg
      541 ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01002028             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:7966:9724
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002028
VERSION     KCVO01002028.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7966:9724"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..419
                     /note="immunoglobulin light chain variable region"
     V_region        104..419
     V_segment       104..385
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <353..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74057.1"
                     /translation="DYYCQSTDSSGFIF"
     J_segment       388..419
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>460
                     /gene="IGLC"
BASE COUNT          101 a          139 c          120 g          100 t
ORIGIN      
        1 acatgggggc tgtggttcta ggaggaagag ctctgggtgt ctcaccatga cctggaccac
       61 tgttctgctc ccctttctca ctctctgcac aggctctgag gcctcctatg agctgacaca
      121 accaccctca gtgtcagtgt ccccaggaca gacggccagg atcacctgct ctggagaaat
      181 actggcaaaa aactatggtc agtggttcca gcagaagcca ggccaggccc ctgtgctgct
      241 gatatttaaa gacagtgaga ggccctcagg gatccctgag cgattctcta gctccagttc
      301 agggacatca attaccttga ccatcagtgg ggcccaggca gaagatgagg ctgactacta
      361 ctgtcaatca acagacagca gtggtttcat cttcggtgct gggacccggc tcaccgtccc
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01002029             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:16876:11488
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002029
VERSION     KCVO01002029.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:16876:11488"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-55"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74058.1"
                     /translation="DYYCAAWDDSLSSPLF"
     J_segment       393..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          150 c          116 g          109 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggata atctccagca tggcctggtt ccctctcgtc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagccaccc
      121 tcaacgtctg gggctcccgg ccagagtgtc accatctctt gctctggaag cagtttcaac
      181 attggaagta attatgtaaa ctggtaccag cagctcccag gaacggcccc caaactcctc
      241 atctatttta gtaatcagcg gccctcaggg gtccctgacc gattctctgg ctctaagtct
      301 ggcacctcag cctccctggc catcactggt ctccgatctg aggatgaggc tgattattac
      361 tgtgcagcat gggatgatag tctgagcagt cccttattcg gaggagggac ccggctgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01002030             347 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:9245:4010
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002030
VERSION     KCVO01002030.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 347)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:9245:4010"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..309
                     /note="immunoglobulin light chain variable region"
     V_region        87..309
     V_segment       87..269
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <231..>281
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74059.1"
                     /translation="DYYCYSTDNSGNHRVFF"
     J_segment       279..309
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        310..>347
                     /gene="IGLC"
BASE COUNT           66 a          106 c           97 g           78 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagc agaagccagg ccagtcccct gttctgatca
      121 tccatgagga cagcagacgg ccctctggga tccctgagag attctctggc tccagttcag
      181 ggacagtggc caccttgact atcagtgggg cccaggtgga ggatgaagct gactactact
      241 gttattcaac agataacagt ggtaatcata gggtcttctt cggagggggg acccggctga
      301 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01002031             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:19226:8644
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002031
VERSION     KCVO01002031.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:19226:8644"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..410
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74060.1"
                     /translation="DYYCGAWDSSLSVRLF"
     J_segment       414..449
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           93 a          154 c          130 g          110 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acgcagccgc cctcagtgtc tggggacccc gggcagaggg tcaccatctc
      181 gtgcactggg agcagctcca acattggagg ttatcttgta tactggtacc agcagttccc
      241 aggaacagcc cccaaactcc tcatctatga caataataag cgaatttcag ggatttctga
      301 ccgattctct ggctccaagt ctggtacctc agcctccctg accatcactg ggctccagcc
      361 tggggatgag gctgattatt actgcggagc atgggatagc agcctgagtg ttcgcttatt
      421 cggaggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCVO01002032             281 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:22429:16434
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002032
VERSION     KCVO01002032.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 281)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22429:16434"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..243
                     /note="immunoglobulin light chain variable region"
     V_region        8..243
     V_segment       8..204
                     /gene="IGLV10-90"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <168..>215
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74061.1"
                     /translation="DYHCSAWDSSLSVVLF"
     J_segment       209..243
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        244..>281
                     /gene="IGLC"
BASE COUNT           58 a           92 c           76 g           55 t
ORIGIN      
        1 acatgggggg agcggcttgg ctgcagcagc accagggcct ccctcccaaa ctgctgtctt
       61 acaggaatac caaccggccc tcggggatct cagagagatt ctctgcatcc aggtcaggaa
      121 acacagcctc cctgaccatc accggactcc aacctgagga tgaggctgac tatcattgct
      181 cagcatggga cagcagtctc agtgttgtct tattcggagg agggacccgg ctgaccgtcc
      241 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01002033             493 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:27815:7211
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002033
VERSION     KCVO01002033.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 493)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:27815:7211"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    131..452
                     /note="immunoglobulin light chain variable region"
     V_region        131..452
     V_segment       131..418
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <380..>427
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74062.1"
                     /translation="DYYCFSSDSSADYWVF"
     J_segment       419..452
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        453..>493
                     /gene="IGLC"
BASE COUNT           97 a          149 c          138 g          109 t
ORIGIN      
        1 acatggggga agagaagcct agggagccca gctgtgctgt gggctcagga ggcagagctc
       61 tgggtgtctc accatggcct ggattcctct cctactcccc ctcctcactt tctgcacagg
      121 ctctgcagcc tcctatgagc tgacacagcc accctcggtg tcagtgtccc caggacagac
      181 ggccaggatc acctgctctg gagatgcatt gccagaaaaa tatgcttatt ggttccagca
      241 gaagccaggc cagtcccctg tgttgatcat ctatgaggac accaaacggc cctctgggat
      301 ccctgagaga ttctctggtt ccagctcagg gacagtggcc accttgacta tcagtggggc
      361 ccaggtggag gatgaagctg actactactg tttctcatca gatagcagtg ctgattattg
      421 ggtgttcggc ggagggaccc ggctgaccgt cccaggtcag cccaaggctg ccccctcggt
      481 cactctcttc ccg
//
LOCUS       KCVO01002034             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:15158:19902
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002034
VERSION     KCVO01002034.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:15158:19902"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..384
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74063.1"
                     /translation="DYYCYSTDSSGNGLF"
     J_segment       385..421
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           95 a          142 c          122 g          100 t
ORIGIN      
        1 acatggggtg ggctcaggag gcagagctct gggtgtctca ccatggcctg gattcctctc
       61 ctactcccca tcctcacttt ctgcacaggc tctgcagcct cctatgagct gacacagcca
      121 ccctcgttgt cagtgtcccc aggacagacg gccaggatca cctgctctgg agatgcattc
      181 ccagaaaaat ttgcttattg gtaccagcag aaaccaggcc agtcccctgt gctgatcatc
      241 tatgaggaca gcaaacggcc ctctgggatc cctgagagat tctctggctc cagctcaggg
      301 acagtggcca ccttgactat cagtggggcc caggtggagg atgaagctga ctactactgt
      361 tactcaacag acagcagtgg taatggctta ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01002035             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:24550:16448
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002035
VERSION     KCVO01002035.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:24550:16448"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74064.1"
                     /translation="DYYCYSTDSSTNHGLF"
     J_segment       375..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           96 a          143 c          112 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtatt gatcatctat gacgacagca
      241 aacggccccc tgggatccct gagagattct ctggctccaa ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gcggaggatg aagctgacta ctactgttac tcaacagata
      361 gcagtactaa tcatggctta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01002036             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:3570:11492
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002036
VERSION     KCVO01002036.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:3570:11492"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..394
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74065.1"
                     /translation="DYYCCSYAGSYLF"
     J_segment       395..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           84 a          158 c          121 g          103 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actatgtctc ctggtaccaa caacatccag gcacagcccc
      241 caaactcatg atttatgagg tcagtaagcg gccctcaggg gtctctgatc gcttctctgc
      301 ctccaagtct ggcaacacgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgctgctcat atgcaggcag ctacttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01002037             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:13754:9499
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002037
VERSION     KCVO01002037.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:13754:9499"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..427
                     /note="immunoglobulin light chain variable region"
     V_region        100..427
     V_segment       100..392
                     /gene="IGLV7-60"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <358..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74066.1"
                     /translation="DYYCFVYYSGTQFF"
     J_segment       397..427
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT          100 a          153 c          114 g           98 t
ORIGIN      
        1 acatgggggg agccagagat cccttccaat accagcacca tggcctggac tctgctcctc
       61 ctccagttcc tcctcacttg ctgcccaggg tccaattctc aggctgtagt gactcaggag
      121 ccctcaatga ctgtgtcccc aggagggaca gtcactctca cctgtggctc cagcactgga
      181 gcagtcacca gtggtaactt tccaaactgg ttccagcaga aacctggaca agtccccagg
      241 ggactgattt acaatacaaa caacaaacac tcctggaccc ctgcccggtt ctcaggctcc
      301 ctcgctgggg gcaaagctgc cctgacactg tcaggagcac agcccgagga cgaggctgat
      361 tattactgct tcgtgtacta tagtggtact caattcttcg gaggagggac ccgactgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01002038             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:9238:11007
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002038
VERSION     KCVO01002038.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9238:11007"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74067.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       386..422
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           98 a          145 c          121 g           96 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc atcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcgttg tcagtgtccc caggacagac ggccaggatc acctgctctg gagacgcatt
      181 gccagaaaaa tatgcttatt ggtaccagca gaaaccaggc cagtccccta tgctgatcat
      241 ctatgaggac aacaaacggc cctctgggat ccctgaaaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcactggggc ccaggtggag gatgaagctg actactactg
      361 ttactcagca gacaacagtg gtcagggctc attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01002039             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:9365:11055
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002039
VERSION     KCVO01002039.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:9365:11055"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..437
                     /note="immunoglobulin light chain variable region"
     V_region        93..437
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74068.1"
                     /translation="DYYCLIWHNNVWVF"
     J_segment       403..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>476
                     /gene="IGLC"
BASE COUNT           97 a          153 c          112 g          114 t
ORIGIN      
        1 acatggggac tgcagggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgc gctgactcag ccaacctccc
      121 tctcagcatc tcctggagca tcagccagat tcacctgcac cttgagcaga ggcatcagtg
      181 ttgatattta taggatattc tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tgaactccca cacagactca gataaacacc agggctctgg agtccccagc cgcttctctg
      301 gatccaaaga tacttcggcc aatgcaggga ttttactcat ctctggcctc cagtctgagg
      361 atgaggctga ctattactgt ttgatttggc acaacaatgt ttgggtattc ggcggaggga
      421 cccggctgac cgtcctaagt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01002040             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:19625:14744
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002040
VERSION     KCVO01002040.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19625:14744"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..408
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74069.1"
                     /translation="DYYCGAWDSGLSVRLF"
     J_segment       412..447
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           91 a          156 c          129 g          109 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggaccccgg gcagagggtc accatctcgt
      181 gcactgggag cagctccaac attggaaatt attttgtata ctggtaccag cagttcccag
      241 gaacagcccc caaactcctc atctatgaca ataataagcg accctcaggg atttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagcctg
      361 gggatgaggc tgattattac tgcggagcat gggatagcgg cctgagtgtt cgcttattcg
      421 gaggagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01002041             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:25497:5283
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002041
VERSION     KCVO01002041.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:25497:5283"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..385
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74070.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       389..423
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           91 a          144 c          125 g          101 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 caaaaaagta tgcttattgg ttccagcaga agccaggcca gtcccctgtg ctgatcatct
      241 atgaggacag cagacggccc tctgggatcc ctgagagatt ctctgcctcc agctcaggga
      301 cagtggccac cttgactatc agtggggccc agggggagga tgaagctgac tactactgtt
      361 attcaatgga tagcagtggt actcagagca tcttcggtgc tgggacccgg ctcaccgtcc
      421 taggtcagcc caaggcttcc cccacggtca ctctgttccc g
//
LOCUS       KCVO01002042             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:8856:17136
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002042
VERSION     KCVO01002042.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:8856:17136"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74071.1"
                     /translation="DYYCYSSESSADYWVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>449
                     /gene="IGLC"
BASE COUNT           89 a          139 c          119 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gacgacagca
      241 aacggccctc tgggatccct gagagattct ctggttccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcatcagaaa
      361 gtagtgctga ttattgggtg ttcggcggag ggacccggct gaccgtccca ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01002043             486 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:13172:8626
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002043
VERSION     KCVO01002043.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 486)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13172:8626"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    118..448
                     /note="immunoglobulin light chain variable region"
     V_region        118..448
     V_segment       118..410
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <373..>420
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74072.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       412..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>486
                     /gene="IGLC"
BASE COUNT           88 a          157 c          131 g          110 t
ORIGIN      
        1 acatgggggg ctctgcttca gctgtgggca caggaggcag cactcaggac agtctccagc
       61 atggcctggt ctcctctcct cctcaccctt ctcattcact gcacagggtc ctgggcccag
      121 tctgtgctga cgcagccgcc ctcagtgtct ggggcgcccg ggcagagggt caccatctcc
      181 tgcactggga gcagttccaa cattggaggt tattatgtgc agtggtacca gcagcttcca
      241 ggaacggccc ccaaactcct catgtatgaa aataataagc gaccctcagg ggtttctgat
      301 cgattctctg gctcccagtc tggtacctca gcctccctga ccatcactgg actccagtct
      361 gaggatgagg ctgattatta ctgccagtcc tatgacagca gcctgagtgc cgtgttattc
      421 ggagcgggga cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      481 ttcccg
//
LOCUS       KCVO01002044             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:13471:18333
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002044
VERSION     KCVO01002044.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:13471:18333"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74073.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       393..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          143 c          123 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctc tgctgatcat
      241 ctatgaagac gacaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaata gatagtagtg gtagtcatag cgtcttcggt gctgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01002045             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:19305:17834
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002045
VERSION     KCVO01002045.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:19305:17834"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74074.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          140 c          139 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgag ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaatg
      181 ttggaagtga atatgtgcac tggtaccaac agaagccatc gcaggcccct gtggtggtca
      241 tccattataa tagtgaccgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgatcata gtttattggg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01002046             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:20514:14073
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002046
VERSION     KCVO01002046.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20514:14073"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    98..443
                     /note="immunoglobulin light chain variable region"
     V_region        98..443
     V_segment       98..404
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74075.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           88 a          161 c          124 g          108 t
ORIGIN      
        1 acatgggggg tctgtggcct cagaggtagc cgtgtccacc atggccctga ctcctctcct
       61 cctcctgctc ctctctcact gcacaggttc cctctcccag cctgtgctga ctcagccacc
      121 ctccctgtct gcatccccgg gagcatcggc cagactcccc tgcaccctga gcagtgacct
      181 cagtgttggt agtaaaaaca tgtactggta ccagcagaag ccagggagcg ctcccaggtt
      241 attcctgtac tactactccg actcagacaa gcagctggga cctggggtcc ccaatcgagt
      301 ctctggctcc aaggagacct caagtaacac agcgtttttg ctcatctctg ggctccagcc
      361 tgaggacgag gccgattatt actgtcaggt gtatgacagt actggagtgt tgttcggagg
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01002047             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:16814:4716
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002047
VERSION     KCVO01002047.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:16814:4716"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74076.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          143 c          125 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagtc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg tgttgatcat
      241 ctatgacgac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcattggggc ccaggtggag gatgaagctg actaccactg
      361 tttctcaaca gatagcagtg gtaatcatag gggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01002048             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:20880:24365
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002048
VERSION     KCVO01002048.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:20880:24365"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74077.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          125 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agccgctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01002049             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:12599:18463
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002049
VERSION     KCVO01002049.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:12599:18463"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..421
                     /note="immunoglobulin light chain variable region"
     V_region        99..421
     V_segment       99..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74078.1"
                     /translation="DYYCYSSDVSGDHRVF"
     J_segment       388..421
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>461
                     /gene="IGLC"
BASE COUNT           92 a          140 c          125 g          104 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 caaaaaaata tgcttattgg ttccagcaga agccaggcca gtcccctgtg ctgatcatct
      241 atgaagacag taaacggccc tctgggatcc ctgagagatt ctctggctcc agttcaggga
      301 cagtggccac cttgactatc agtggggccc aggtggagga tgaagctgac tactactgtt
      361 actcatcaga tgtcagtggt gatcataggg tattcggcgg agggacccgg ctgaccgtcc
      421 ttggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01002050             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:13537:15373
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002050
VERSION     KCVO01002050.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:13537:15373"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74079.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       392..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           93 a          145 c          124 g          104 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttctt ggttccagca gaagccaggc cagtcccctg tgcttatcat
      241 ctatgacgac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcattggggc ccaggtggag gatgaagctg actaccactg
      361 tttctcaaca gatagcagtg gtaatcatag gggcttattc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01002051             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:24946:13871
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002051
VERSION     KCVO01002051.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:24946:13871"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..412
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74080.1"
                     /translation="DYHCQSYDSSLSAWVF"
     J_segment       413..449
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           86 a          160 c          126 g          115 t
ORIGIN      
        1 acatggggta gctctgcttc atctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctcg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtgctg acacagccgc cctcagtgtc tggggcccca gggcagaggg tcaccatctc
      181 ctgcactggg agcagttcca tcattggaga ttattttgta tactggtatc agcagttccc
      241 aggaatggcc cccaaactcc tcatctatga caataataag cggccctcag ggctttctgc
      301 ccgattctct ggctccaagt ccggtacctc tgcctccctg accatcactg ggctccagac
      361 tgaggatgag gctgattatc actgccagtc ctatgacagt agcctgagtg cttgggtgtt
      421 cggcgggggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCVO01002052             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:5439:4453
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002052
VERSION     KCVO01002052.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:5439:4453"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74081.1"
                     /translation="DYYCQSYDNSLSAVFF"
     J_segment       410..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           88 a          160 c          126 g          110 t
ORIGIN      
        1 acatggggct ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct cctctcctcc tcacccttct cattcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagtgtctgg ggcgcccggg cagacggtca ccatctcctg
      181 cactgggagc agctccaaca ttggaggtta ttatgtgcag tggtaccagc agcttccagg
      241 aacggccccc aaactcctca tctatgaaaa taataagcga ccctcagggg tttctgatcg
      301 attctctggc tcccagtctg gtacctcagc ctccctgacc atcactggac tccagtctga
      361 ggatgaggct gattattact gccagtccta tgacaacagc ctgagtgccg tgtttttcgg
      421 aggcgggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCVO01002053             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:17552:14407
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002053
VERSION     KCVO01002053.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:17552:14407"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..447
                     /note="immunoglobulin light chain variable region"
     V_region        117..447
     V_segment       117..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74082.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       411..447
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        448..>485
                     /gene="IGLC"
BASE COUNT           90 a          158 c          128 g          109 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaggtt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaactcctc atatatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggtacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcag cctgagtgcc gtgttattcg
      421 gagcagggac ccggctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01002054             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:23114:14710
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002054
VERSION     KCVO01002054.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:23114:14710"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..257
                     /note="immunoglobulin light chain variable region"
     V_region        7..257
     V_segment       7..226
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <189..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74083.1"
                     /translation="DYFCSSYTGSITLF"
     J_segment       227..257
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        258..>296
                     /gene="IGLC"
BASE COUNT           62 a           94 c           70 g           70 t
ORIGIN      
        1 acatgggcag tgacatcggt gcttataact atgtctcctg gtaccaacgg cacccaggca
       61 aagcccccaa actcatgatt tatgatgtca ataagcggcc ctcaggggtc tctgatcgct
      121 tctctggctc caaatctggc aacacggcct ccctgaccat ctctgggctc cagtctgagg
      181 atgaggctga ttatttctgc agctcatata caggcagcat cactttattc ggaggaggga
      241 cccggctgac cgtcctacgt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01002055             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:18073:10190
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002055
VERSION     KCVO01002055.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18073:10190"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74084.1"
                     /translation="DYYCQVWDSTNDHILF"
     J_segment       395..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          147 c          135 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaga taaatatgta cactggtacc agcagaagcc agcgcgggcc cctgtgctgg
      241 tcatctacta tgatagtgac cggccctcat ggatccctga gcgattctct gggtccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt actaatgatc atatcttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01002056             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:8136:3993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002056
VERSION     KCVO01002056.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:8136:3993"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..453
                     /note="immunoglobulin light chain variable region"
     V_region        120..453
     V_segment       120..413
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74085.1"
                     /translation="YYYCLSYDSSLSAHYIF"
     J_segment       416..453
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           96 a          167 c          119 g          109 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctc gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacacagcca ccctcagtgt ctggggcccc agggcagagg gtcaccatct
      181 cgtgcactgg gagcagctcc agcattggag gtgattatgt atcctggtac caacagctcc
      241 caggaacgac ccccaaactc ctcatctatc aaaataataa gcgaccccca ggggtttctg
      301 accgattctc tggctccaag tctggtacct cagcctccct gaccatcact gggctccaga
      361 ctgaggatga ggcttattac tactgcctgt cctatgacag cagcctgagt gctcattaca
      421 tcttcggtcc tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca
      481 ctctgttccc g
//
LOCUS       KCVO01002057             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:12370:8918
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002057
VERSION     KCVO01002057.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:12370:8918"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74086.1"
                     /translation="DYYCYSSDSSADYWVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>449
                     /gene="IGLC"
BASE COUNT           87 a          139 c          121 g          102 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggttccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aggctgacta ctactgttac tcatcagata
      361 gcagtgctga ttattgggtg ttcggcggag ggacccggct gaccgtccca ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01002058             292 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:21633:7630
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002058
VERSION     KCVO01002058.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 292)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:21633:7630"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..254
                     /note="immunoglobulin light chain variable region"
     V_region        8..254
     V_segment       8..214
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <179..>226
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74087.1"
                     /translation="DYFCSVWDSSLSSYIF"
     J_segment       217..254
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        255..>292
                     /gene="IGLC"
BASE COUNT           59 a           90 c           71 g           72 t
ORIGIN      
        1 acatgggggg gcgggttatt ctgtatcctg gtaccagcag ttcccaggaa cagcccccaa
       61 actcctcatc tatgaaaata ataagcgacc ctcaggggtt tctgaccgat tctctggctc
      121 caagtctggt acctcagcct ccctgaccat cgctggactc caatctgagg atgaggctga
      181 ttatttctgc tcagtctggg atagcagcct gagtagttac atcttcggta ctgggacccg
      241 gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc cg
//
LOCUS       KCVO01002059             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:17029:12566
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002059
VERSION     KCVO01002059.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:17029:12566"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    90..421
                     /note="immunoglobulin light chain variable region"
     V_region        90..421
     V_segment       90..381
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <345..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74088.1"
                     /translation="DYYCQSSDTSLNDHVLF"
     J_segment       386..421
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>461
                     /gene="IGLC"
BASE COUNT           92 a          153 c          111 g          105 t
ORIGIN      
        1 acatgggggc agcactcagg acagtctcca gcatggcctc gtctcctctc ctcctcaccc
       61 ttctcattca ctgcacaggg tcctgggccc agtctgtgct gacacagccg ccctcagtgt
      121 ctggggcccc agggcagagg atcaccatct cctgcactgg gagcagctcc aacattggag
      181 gttattatgt atactggtac cagcaactcc caggaatggc ccccaaactc ctcatctatg
      241 acaataataa gcgaccctca ggggtttctg accgattctc tggctccaag tctggtacct
      301 cagcctccct gaccatcgct gggctccaga ctgaggatga ggctgattat tactgccaat
      361 cctctgacac cagtctaaat gatcatgtgt tattcggagg agggacccgg ctgagcgtcc
      421 tcggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01002060             413 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:10624:16553
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002060
VERSION     KCVO01002060.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 413)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:10624:16553"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    62..375
                     /note="immunoglobulin light chain variable region"
     V_region        62..375
     V_segment       62..340
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <303..>347
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74089.1"
                     /translation="EYYCSSYADIYTFVF"
     J_segment       341..375
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        376..>413
                     /gene="IGLC"
BASE COUNT           76 a          133 c          108 g           96 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 ggcctcgctc agtgtctggg tctcctggac agtcggtcac catctcctgc acgggcacca
      121 gcagtgacat cggtggttac aactttgtct cctggtacca acaccatcca gacacagccc
      181 ccaaactcgt gatttatgag gtcactcagc ggccctcagg ggtctctgat cggttctctg
      241 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggacgagg
      301 ctgaatatta ctgcagttca tatgcagaca tctacacatt tgtgttcgga agtggcacca
      361 agttgaccgt cctcggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01002061             525 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:20153:6106
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002061
VERSION     KCVO01002061.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 525)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 525)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..525
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:20153:6106"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    157..487
                     /note="immunoglobulin light chain variable region"
     V_region        157..487
     V_segment       157..449
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <412..>459
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74090.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       451..487
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        488..>525
                     /gene="IGLC"
BASE COUNT          100 a          169 c          136 g          120 t
ORIGIN      
        1 acatggggaa gctctgcttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagaag cagaatcatg
      121 atgcctgtgt ctctcccact tccagggtcc tgggcccagt ctgtgctgac gcagccgccc
      181 tcagtgtctg gggcgcccgg gcagagggtc accatctcct gcactgggag cagttccaac
      241 attggaggtt attatgtgca gtggtaccag cagcttccag gaacggcccc caaactcctc
      301 atgtatgaaa ataataagcg accctcaggg gtttctgatc gattctctgg ctcccagtct
      361 ggtacctcag cctccctgac catcactgga ctccagtctg aggatgaggc tgattattac
      421 tgccagtcct atgacagcag cctgagtgcc gtgttattcg gagcagggac ccggctgacc
      481 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01002062             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:14101:17381
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002062
VERSION     KCVO01002062.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:14101:17381"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..383
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74091.1"
                     /translation="DYYCQVWDSSSAVLF"
     J_segment       386..423
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           86 a          141 c          134 g          100 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactgcacag actctcttgt ctcctatgaa ttgactcagc
      121 cacgctcagt gtccgtgtcc ccaggacaga cggccaggat cacctgtggg ggatacatca
      181 ttggaagtaa aagtgtgcag tggtaccagc agaagccacc gcaggccctt gtgctggtca
      241 tctatgctga taacaaacgg ccctcaggga tccctgagcg attctctggc tccaatttag
      301 ggatcaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagt agtgctgtgt tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01002063             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:19367:15895
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002063
VERSION     KCVO01002063.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19367:15895"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74092.1"
                     /translation="DYYCQVWDSSTNHILF"
     J_segment       395..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          145 c          136 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgt ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaga taaatatgta cactggtacc agcagaagcc agcgcgggcc cctgtgctgg
      241 tcatctacta tgatagtgac cggccctcat ggatccctga gcgattctct gggtccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtactaatc atatcttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01002064             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:9311:4297
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002064
VERSION     KCVO01002064.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:9311:4297"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74093.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       392..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           90 a          143 c          126 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac agcaaatggc cctctgggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gacagtagtg gtaattatgt cttcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01002065             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:17611:10629
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002065
VERSION     KCVO01002065.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:17611:10629"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74094.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       395..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           87 a          142 c          139 g           98 t
ORIGIN      
        1 acatgggggc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gtctcctatg agctcactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggaggcaa
      181 tgttggaagt gaatatgtcc actggtatca acagaagcca ccgcaggccc ctgtggtggt
      241 catctattat aatagtgacc ggccctcagg gatccctgag cgattctctg gctccaaatc
      301 agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagt ctgactatta
      361 ctgtcaggtg tgggacagta ggagtgatca tagtttattg ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01002066             342 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1106:24455:13309
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002066
VERSION     KCVO01002066.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 342)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1106:24455:13309"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..304
                     /note="immunoglobulin light chain variable region"
     V_region        7..304
     V_segment       7..267
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <229..>276
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74095.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       269..304
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        305..>342
                     /gene="IGLC"
BASE COUNT           69 a          106 c           92 g           75 t
ORIGIN      
        1 acatgggggg accccgggca gagggtcacc atctcgtgca ctgggagcag ctccaacatt
       61 ggaggttatt ttgtgtactg gtaccagcag ttcccacgaa cagcccccaa actcctcatc
      121 tatgacaata ataagcgacc ctcagggatt tctgaccgat tctctggctc caagtctggt
      181 acctcagcct ccctgaccat cactgggctc cagcctgggg atgaggctga ttattactgc
      241 ggagcatggg atagcagcct gagtgctcgc ttattcggag gagggacccg gctgaccgtc
      301 ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01002067             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:28472:16158
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002067
VERSION     KCVO01002067.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:28472:16158"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    93..438
                     /note="immunoglobulin light chain variable region"
     V_region        93..438
     V_segment       93..402
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <369..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74096.1"
                     /translation="DYYCMIWHNNVWVF"
     J_segment       403..438
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           90 a          152 c          120 g          114 t
ORIGIN      
        1 acatggggac tgcggggaaa gaggctgtgt ccaccatggc ctggactcct ctcctcctcc
       61 tgctcctctc tcactgcaca ggttccctct cgcagcctgt gctgactcag ccaccctccc
      121 tctcagcatc tcctggagca tcagccagac tcacctgcac cttgcgcagt ggcatcagtg
      181 ttggtagtta caggatattc tggtaccagc agaagccagg gagtcctccc cggtatcttc
      241 tggactacca cacagactca gataagcacc agggatctgg agtccccagc cgcttctctg
      301 gatccaatga tgcttcggcc aatgcaggga ttttactcat ctctggactc cagtctgagg
      361 atgaggctga ctattattgt atgatttggc acaacaatgt ttgggtgttc ggcggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01002068             303 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:13839:13813
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002068
VERSION     KCVO01002068.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 303)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:13839:13813"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    1..265
                     /note="immunoglobulin light chain variable region"
     V_region        1..265
     V_segment       1..228
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <190..>237
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74097.1"
                     /translation="DYYCQVWDSSSDHILF"
     J_segment       231..265
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        266..>303
                     /gene="IGLC"
BASE COUNT           64 a           86 c           90 g           63 t
ORIGIN      
        1 acatgggggg gagacaacct tggagataaa tatgtacact ggtaccagca gaagccaccg
       61 cgggcccctg tgctggtcat ctactatgat agtgaccggc cctcatggat ccctgagcga
      121 ttctctgggt ccaaatcagg gatcaccgcc accctgacca tcagcggggt cgaggccggg
      181 gatgaggctg actattactg tcaggtgtgg gacagtagta gtgatcatat cttattcgga
      241 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      301 ccg
//
LOCUS       KCVO01002069             490 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:16610:17449
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002069
VERSION     KCVO01002069.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 490)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:16610:17449"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    128..452
                     /note="immunoglobulin light chain variable region"
     V_region        128..452
     V_segment       128..415
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <377..>424
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74098.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       420..452
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        453..>490
                     /gene="IGLC"
BASE COUNT           99 a          147 c          135 g          109 t
ORIGIN      
        1 acatggggga gaagcctagg gagcccagct gtgctgtggg ctcaggaggc agagctctgg
       61 gtgtctcacc atggcctgga ttcctcttct actccccctc ctcactttct gcacaggctc
      121 tgcagcctcc tatgagctga cacagccacc ctcggtgtca gtgtccccag gacagacggc
      181 caggatcacc tgctctggag atgcattgcc aaaaaagtat gcttattggt tccagcagaa
      241 gccaggccag tcccctgtgt tgatcatcta tgaagacgac aaacggccct ctgggatccc
      301 tgagagattc tctggctcca gctcagggac agtggccacc ttgactatca gtggggccca
      361 ggtggaggat gaaggtgact actactgtta ctcaatagac agtagtggta gtcatagcgt
      421 cttcggtgct gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac
      481 tctgttcccg
//
LOCUS       KCVO01002070             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:19791:12834
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002070
VERSION     KCVO01002070.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:19791:12834"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74099.1"
                     /translation="DYYCSSYTDSSTWLF"
     J_segment       404..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           83 a          156 c          124 g          109 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggagccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctctggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacagacag tagcacttgg cttttcggcg gagggacccg
      421 gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01002071             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:10922:21224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002071
VERSION     KCVO01002071.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:10922:21224"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    121..442
                     /note="immunoglobulin light chain variable region"
     V_region        121..442
     V_segment       121..408
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74100.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       412..442
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           93 a          150 c          133 g          104 t
ORIGIN      
        1 acatggggct agggagccca gctgtgctgt gggctcagga ggcagagctc tgggtgtctc
       61 accatggcct ggattcctct cctactcccc ctcctcactt tctgcacagg ctctgcagcc
      121 tcctatgagc tgacacagcc accctcggtg tcagtgtccc caggacagac ggccaggatc
      181 acctgctctg gagatgcatt gccagaaaaa tatgcttatt ggttccagca gaagccaggc
      241 cagtcccctg tgctgatcat caatgaggac agcaaacggc cctctgggat ccctgggaga
      301 ttctctggct ccagctcagg gacagtggcc accttgactc tcagtggggc ccaggtggag
      361 gatgaagctg actactactg ttcctcaaca gacagtagtg gtaattatgt cttcggcgga
      421 gggacccggc tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01002072             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:7899:13437
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002072
VERSION     KCVO01002072.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:7899:13437"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..409
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74101.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       411..446
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           89 a          157 c          129 g          109 t
ORIGIN      
        1 acatggggct ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct cctctcctcc tcacccttct cattcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagtgtctgg ggaccccggg cagagggtca ccatctcgtg
      181 cactgggagc agctccaaca ttggaggtta ttttgtatac tggtaccagc agttcccagg
      241 aacagccccc aaactcctca tctatgacaa ttataagcga ccctcaggga tttctgaccg
      301 attctctggc tccaagtctg gtacctcagc ctccctgacc atcactgggc tccagcctgg
      361 ggatgaggct gattattact gcggagcatg ggatagcagc ctgagtgctc gcttattcgg
      421 aggagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCVO01002073             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:19544:9727
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002073
VERSION     KCVO01002073.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19544:9727"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..423
                     /note="immunoglobulin light chain variable region"
     V_region        99..423
     V_segment       99..380
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74102.1"
                     /translation="DYYCYSTDSSGSTGLF"
     J_segment       386..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           93 a          144 c          122 g          102 t
ORIGIN      
        1 acatgggggg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccct cctcactttc tgcacaggct ctgcagcctc ctctgagctg acacagccac
      121 cctcggtgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 caaaatacta tgcttattgg ttccaacaga agccaggcca gtcccctgtg gcgatcatct
      241 atgaggacaa caaacggccc tctgggatcc ctgagagatt ctctggctcc agctcaggga
      301 cagtggccac tttgactatc agtggggccc aggtagagga tgaagctgac tactactgtt
      361 actcaacaga tagcagtggt tctactggct tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01002074             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:15043:9656
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002074
VERSION     KCVO01002074.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:15043:9656"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..395
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74103.1"
                     /translation="DYYCCSYAGTYLF"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           84 a          156 c          121 g          106 t
ORIGIN      
        1 acatggggtg gggtctcaga cggcagcgct ctcgggacat ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gtcctgactc
      121 agcctcgctc agtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cggtggtaat aattatgtct cctggtacca gcaacatcca ggcacagccc
      241 ccaaattcat catttatgag gtcagtaagc ggccctcagg ggtctctgat cgcttctctg
      301 gctccaagtc tggcaacacg gcctccctga ccatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgctgctca tatgcaggca cctacttatt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01002075             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:5394:10514
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002075
VERSION     KCVO01002075.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:5394:10514"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74104.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       394..426
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          142 c          125 g          104 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccaaaaaa gtatgcttat tggttccagc agaagccagg ccagtcccct gtgctgatca
      241 tctatgaaga cgacaaacgg ccctctggga tccctgagag attctctggc tccagctcag
      301 ggacagtggc caccttgact atcagtgggg cccaggtgga ggatgaagct gactactact
      361 gttactcaat agatagtagt ggtagtcata gcgtcttcgg tgctgggacc cggctcaccg
      421 tcctaggtca gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCVO01002076             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:19928:17443
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002076
VERSION     KCVO01002076.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:19928:17443"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74105.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           86 a          156 c          122 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttcgtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01002077             457 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:13524:14316
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002077
VERSION     KCVO01002077.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 457)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:13524:14316"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..419
                     /note="immunoglobulin light chain variable region"
     V_region        101..419
     V_segment       101..382
                     /gene="IGLV3-20"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
     CDS             <350..>391
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74106.1"
                     /translation="DYYCQSTDSSGYIF"
     J_segment       383..419
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        420..>457
                     /gene="IGLC"
BASE COUNT          102 a          134 c          117 g          104 t
ORIGIN      
        1 acatgggggt ggttctagga ggaagagctc tgggtgtctc accatgacct ggaccactgt
       61 tctgctcccc tttctcactc tctgcacagg ctctgtggcc tcctatgagc tgacacagcc
      121 accctcagtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagaaatact
      181 gacaaaaaat tttgctcagt ggttccagca gaagccaggc caggcccctg tactgctgat
      241 atataaagac agtgagaggc cctcagggat ccctgagcga ttctctagtt ccagttcagg
      301 gacaacagtt accttgacca tcagtcgggc ccaggtagaa gatgaggctg actattattg
      361 tcaatcaaca gacagcagtg gttacatctt cggtgctggg acccggctca ccgtcctagg
      421 tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01002078             426 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:11770:9166
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002078
VERSION     KCVO01002078.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 426)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:11770:9166"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    58..388
                     /note="immunoglobulin light chain variable region"
     V_region        58..388
     V_segment       58..352
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <316..>360
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74107.1"
                     /translation="DYYCSSYTSTTTWLF"
     J_segment       353..388
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        389..>426
                     /gene="IGLC"
BASE COUNT           77 a          145 c          105 g           99 t
ORIGIN      
        1 acatgggggg ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag
       61 gctgccctga ctcagtctcc ctctgtgtct gggtctcctg gacagtcggt caccatttcc
      121 tgcactggaa ccagcagtga cattggtggt tataaccgtg tctcctggta ccaacagcac
      181 ccaggcaaag cccccaaact catgatttat gacgtcagtg atcggccctc aggggtctct
      241 gatcgcttct ctggttccaa gtctggcaac acggcctccc tgatcatctc tgggctccag
      301 gctgaggacg aggctgatta ttactgcagc tcatacacaa gcactaccac ttggctattc
      361 ggcggaggga cccgcctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc
      421 ttcccg
//
LOCUS       KCVO01002079             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:10952:16892
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002079
VERSION     KCVO01002079.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:10952:16892"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..382
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74108.1"
                     /translation="DYYCQVWDSSSAVLF"
     J_segment       385..422
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           86 a          140 c          135 g           99 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct cactgcacag actctgtgtc tcctatgaat tgactcagcc
      121 acgctcagtg tccgtgtccc caggacagac ggccaggatc acctgtgggg gatacatcat
      181 tggaagtaaa agtgtgcagt ggtaccagca gaagccaccg caggcccttg tgctggtcat
      241 ctatgctgat aacaaacggc cctcagggat ccctgagcga ttctctggct ccaatttagg
      301 gatcaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtagta gtgctgtgtt attcggagga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01002080             527 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:24226:8753
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002080
VERSION     KCVO01002080.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 527)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 527)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..527
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:24226:8753"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    159..489
                     /note="immunoglobulin light chain variable region"
     V_region        159..489
     V_segment       159..451
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <414..>461
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74109.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       453..489
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        490..>527
                     /gene="IGLC"
BASE COUNT          101 a          162 c          147 g          117 t
ORIGIN      
        1 acatggggga ctctcagagc atgaagaggg gcagggagag atttggggaa gctctgcttc
       61 agctgtgggc acaggaggca gcactcagga cagtctccag catggcctgg tctcctctcc
      121 tcctcaccct tctcattcac tgcacagggt cctgggccca gtctgtgctg acgcagccgc
      181 cctcaatgtc tggggcgccc gggcaggggg tcaccatctc ctgcactggg agcagctcca
      241 acattggaga ttattatgtg cagtggtacc agcagtttcc aggtacggcc cccagactcc
      301 tcatctatga aaataataaa cgaccctcag gggtttctga tcgattctct ggctcccagt
      361 ctggtacctc agcctccctg accatcgctg gactccagtc tgaggatgag gctgattatt
      421 actgccagtc ctatgacagc agcctgagtg ccgtgttatt cggaggaggg acccggctga
      481 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01002081             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:16329:19224
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002081
VERSION     KCVO01002081.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:16329:19224"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74110.1"
                     /translation="DYYCCSYAGRFTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           82 a          157 c          124 g          112 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactgggac
      181 cagcagtgac atcggtggtt ataactttgt ctcctggtac caacagcatg caggcacagc
      241 ccccaaactc atgatttatg aggtcagtaa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tccggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 cactgattat tactgctgct catatgcagg caggttcact tttgtgttcg gaagtggcac
      421 caagttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01002082             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:10949:11447
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002082
VERSION     KCVO01002082.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:10949:11447"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..446
                     /note="immunoglobulin light chain variable region"
     V_region        117..446
     V_segment       117..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74111.1"
                     /translation="DYYCQSFDSSLSAVLF"
     J_segment       411..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>485
                     /gene="IGLC"
BASE COUNT           88 a          158 c          130 g          109 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tctctgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagcgccaac attgggggtt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaactcctc atctatgaaa ataataagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggaacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggg tgattattac tgccagtcct ttgacagcag cctgagtgcc gtgttattcg
      421 gaggagggac ccggctgacc gtcctaagtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01002083             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:12915:19896
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002083
VERSION     KCVO01002083.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:12915:19896"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..426
                     /note="immunoglobulin light chain variable region"
     V_region        105..426
     V_segment       105..386
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74112.1"
                     /translation="DYYCQVWDSSSDVFF"
     J_segment       389..426
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           85 a          143 c          140 g           96 t
ORIGIN      
        1 acatgggggg cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca cagactctgt ggtctcctat gaattgactc
      121 agccacgctc agtgtccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 gcattggaag tagaagtgtg cagtggtacc agcagaagcc accgcaggcc cttctactgg
      241 tcatctatgc tgatagcgaa cggccctcag ggatccctga gcgattctct ggctccaatt
      301 tagggaacac cgccaccctg accatcagcg gcgtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatg tgttcttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01002084             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:17354:14834
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002084
VERSION     KCVO01002084.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:17354:14834"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..446
                     /note="immunoglobulin light chain variable region"
     V_region        117..446
     V_segment       117..409
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74113.1"
                     /translation="DYYCQSYDSTLSAVLF"
     J_segment       411..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>485
                     /gene="IGLC"
BASE COUNT           90 a          159 c          126 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag caactccaac attggagttt attatgtgca gtggtaccag caacttccag
      241 gaacggcccc caaagttctc atctatgaaa ataatcagcg accctcaggg gtttctgatc
      301 gattctctgg ctcccagtct ggtacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct acgacagcac cctgagtgcc gtgttgttcg
      421 gaggagggac ccggctgacc gtcctaagtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01002085             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:13942:17067
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002085
VERSION     KCVO01002085.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:13942:17067"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..410
                     /note="immunoglobulin light chain variable region"
     V_region        87..410
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74114.1"
                     /translation="DYYCYSIDSSGSHSVF"
     J_segment       379..410
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        411..>449
                     /gene="IGLC"
BASE COUNT           93 a          140 c          116 g          100 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gcgcaggaga tgcattgcca aaaaagtatg
      181 cttattggtt ccagcagaag ccaggccagt cccctgtgct gatcatctat gaagacgaca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aaagtgacta ctactgttac tcaatagata
      361 gtagtggtag tcatagcgtc ttcggtgctg ggacccggct caccgtccta cgtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01002086             503 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:8214:16455
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002086
VERSION     KCVO01002086.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 503)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 503)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..503
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:8214:16455"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    135..465
                     /note="immunoglobulin light chain variable region"
     V_region        135..465
     V_segment       135..428
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <390..>437
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74115.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       430..465
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        466..>503
                     /gene="IGLC"
BASE COUNT           98 a          161 c          128 g          116 t
ORIGIN      
        1 acatggggac aggaggcagc actcaggaca gtctccagca tggcctggtc tcctctcctc
       61 ctcacccttc tcattcactg cacagaagca gaatcatgat tcctgtgtct cttccacttc
      121 cagggtcctg ggcccagtct gtgctgacgc agccgccctc agtgtctggg gaccccgggc
      181 agagggtcac catctcgtgc actgggagca gctccaacat tggaggttat tttgtatatt
      241 ggtaccagca gttcccagga acagccccca aactcctcat ctatgacaat aataagcgac
      301 cctcagggat ttctgaccga ttctctggct ccaagtctgg tacctcagcc tccctgacca
      361 tcactgggct ccagcctggg gatgaggctg attattactg cggagcatgg gatagcagcc
      421 tgagtgctcg cttattcgga ggagggaccc gtctgaccgt cctaggtcag cccaaggctg
      481 ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01002087             395 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:20608:16761
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002087
VERSION     KCVO01002087.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 395)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:20608:16761"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    27..357
                     /note="immunoglobulin light chain variable region"
     V_region        27..357
     V_segment       27..321
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <285..>329
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74116.1"
                     /translation="DYYCSSYASSSTWIF"
     J_segment       322..357
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        358..>395
                     /gene="IGLC"
BASE COUNT           76 a          125 c          104 g           90 t
ORIGIN      
        1 acatgggggg cacaggatcc tgggctcagg ctgccctgac tcagtctccc tctgtgtctg
       61 ggtctcctgg acagtcggtc accatttcct gcactggaac cagcagtgac attggtgatt
      121 ataaccgtgt ctcctggtac caacagcacc caggcaaagc ccccaaactc ataatttatg
      181 aggtcagtga tcggccctca ggggtctctg atcgcttctc tggctccaag tctggcaaca
      241 cggcctccct gatcatctct gggctccagg ctgaggacga ggctgattat tactgcagct
      301 catacgcaag cagtagcact tggatattcg gcggagggac ccggctgacc gtcctaggtc
      361 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01002088             335 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:22450:13241
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002088
VERSION     KCVO01002088.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 335)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:22450:13241"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    9..297
                     /note="immunoglobulin light chain variable region"
     V_region        9..297
     V_segment       9..261
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <225..>269
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74117.1"
                     /translation="DYYCSSYADTTTWLF"
     J_segment       262..297
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        298..>335
                     /gene="IGLC"
BASE COUNT           67 a          108 c           85 g           75 t
ORIGIN      
        1 acatgggggg acagtcggtc accatttcct gcactggaac cagcagtgac attggtggtt
       61 ataaccgtgt ctcctggtac caacagcacc caggcaaagc ccccaaactc atgatttatg
      121 acgtcagtga tcggccctca ggggtctctg atcgcttctc tggttccaag tctggcaaca
      181 cggcctccct gatcatctct gggctccagg ctgaggacga ggctgattat tactgcagct
      241 catacgcaga cactaccact tggctattcg gcggagggac ccgcctgacc gtcctaggtc
      301 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01002089             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:18108:14524
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002089
VERSION     KCVO01002089.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:18108:14524"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74118.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           85 a          155 c          125 g          108 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtaatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacgcaagca gtagcacttg ggttttcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01002090             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:17631:17034
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002090
VERSION     KCVO01002090.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:17631:17034"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..445
                     /note="immunoglobulin light chain variable region"
     V_region        100..445
     V_segment       100..406
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <376..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74119.1"
                     /translation="DYYCHLYDSTGVLF"
     J_segment       409..445
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          162 c          123 g          109 t
ORIGIN      
        1 acatgggggg ggtctgtggc ctcagaggta gccgtgtcca ccatggccct gactcctctc
       61 ctcctcctgc tcctctctca ctgcacaggt tccctctccc agcctgtgct gactcagcca
      121 ccctccctgt ctgcatcccc gggagcatcg gccagactcc cctgcaccct gagcagtgac
      181 ctcagtgttg gtagtaaaaa catgtactgg taccagcaga agccagggag cgctcccagg
      241 ttattcctgt actactactc cgactcagac aaacagctgg gacctggggt ccccaatcga
      301 gtctctggct ccaaggagac ctcaagtaac acagcgtttt tgctcatctc tgggctccag
      361 cctgaggacg aggccgatta ttactgtcac ttgtatgaca gtactggagt gttgttcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01002091             484 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:8824:10252
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002091
VERSION     KCVO01002091.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 484)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 484)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..484
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8824:10252"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    116..446
                     /note="immunoglobulin light chain variable region"
     V_region        116..446
     V_segment       116..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <371..>418
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74120.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       410..446
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        447..>484
                     /gene="IGLC"
BASE COUNT           89 a          156 c          129 g          110 t
ORIGIN      
        1 acatgggggt ctgcttcagc tgtgggcaca ggaggcagca ctcaggacag tctccagcat
       61 ggcctggtct cctctcctcc tcacccttct cattcactgc acagggtcct gggcccagtc
      121 tgtgctgacg cagccgccct cagtgtctgg ggcgcccggg cagagggtca ccatctcctg
      181 cactgggagc agttccaaca ttggaggtta ttatgtgcag tggtaccagc agcttccagg
      241 aacggccccc aaactcctca tgtatgaaaa taataagcga ccctcagggg tttctgatcg
      301 attctctggc tcccagtctg gtacctcagc ctccctgacc atcactggac tccagtctga
      361 ggatgaggct gattattact gccagtccta tgacagcagc ctgagtgccg tgttattcgg
      421 agcagggacc cggctgaccg tcctaggtca gcccaaggct gccccctcgg tcactctctt
      481 cccg
//
LOCUS       KCVO01002092             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:5815:19706
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002092
VERSION     KCVO01002092.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:5815:19706"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74121.1"
                     /translation="DYYCSSRDSSGNYVF"
     J_segment       375..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           89 a          139 c          119 g           99 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatttg
      181 cttattggtt ccaacagaag ccaggccagt cccctgtgct gatcatcaat gaggacagca
      241 agcggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aaggtgacta ctactgttcc tcaagagata
      361 gcagtggtaa ttatgtattc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01002093             487 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:11556:12786
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002093
VERSION     KCVO01002093.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:11556:12786"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    119..449
                     /note="immunoglobulin light chain variable region"
     V_region        119..449
     V_segment       119..411
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <374..>421
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74122.1"
                     /translation="DYYCQSYDTRLRAWVF"
     J_segment       413..449
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>487
                     /gene="IGLC"
BASE COUNT           95 a          159 c          125 g          108 t
ORIGIN      
        1 acatggggaa gctctgtttc agctgtgggc acaggaggca gcactcagga cagtctccag
       61 catggcctgg tctcctctcc tcctcaccct tctcattcac tgcacagggt cctgggccca
      121 gtctgtcctg acgcagccgc cctcagtgtc tggggcgccc ggacagaggg tcaccatctc
      181 ctgcactggg agcagctcca acattggaga ttattttgta cagtggtacc aacagcttcc
      241 aggaacggcc cccaaactcc tcatctatga aaatgataaa cggccctcag gagtttctga
      301 tcgattctct ggctcccagt ctggaacctc agcctccctg accatcactg gactccagtc
      361 tgaggatgag gctgattact actgccagtc ctatgacacc agattgaggg cctgggtatt
      421 cggcggaggg acccggctga ccgtcctagg tcagcccaag gctgccccct cggtcactct
      481 cttcccg
//
LOCUS       KCVO01002094             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:12026:20847
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002094
VERSION     KCVO01002094.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:12026:20847"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74123.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       395..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           88 a          145 c          133 g           97 t
ORIGIN      
        1 acatggggtg gcctcgggaa gcagccttgg cggtgcctca gccatggccg ggacccttct
       61 cctcctcggc ctccttgctt actgcacagg ctctgcggtc tcctatgagc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacct
      181 tggagataaa tatctacact ggtaccacca gaagccagcg caggcccctg tgctggtcat
      241 ctactatgat agtgaccggc cctcatggat ccctgagcga ttctctgggt ccaagtcagg
      301 gaacaccgcc accctgacca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacagtaata atgatcatat ctttttcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01002095             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:8516:9469
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002095
VERSION     KCVO01002095.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:8516:9469"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..453
                     /note="immunoglobulin light chain variable region"
     V_region        120..453
     V_segment       120..411
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74124.1"
                     /translation="DYYCLSYDSSLSGHYIF"
     J_segment       416..453
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           96 a          165 c          121 g          109 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctc gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacacagcca ccctcagtgt ctggggcccc agggcagagg gtcaccatct
      181 cgtgcactgg gagcagctcc agcattggag gtgattatgt atcctggtac caacagctcc
      241 caggaacgac ccccaaactc ctcatctatc aaaataataa gcgaccctca ggggtttctg
      301 gccgattctc tggctccaag tctggtacct cagcctccct gaccatcact ggactccaga
      361 ctgaggatga ggctgattac tactgcctgt cctatgacag cagcctgagt ggtcattaca
      421 tcttcggtcc tgggacccgg ctcaccgtcc taggtcagcc caaggcttcc cccacggtca
      481 ctctgttccc g
//
LOCUS       KCVO01002096             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:21581:11763
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002096
VERSION     KCVO01002096.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:21581:11763"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    112..445
                     /note="immunoglobulin light chain variable region"
     V_region        112..445
     V_segment       112..405
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74125.1"
                     /translation="DYYCLSYDSSLSAHYFF"
     J_segment       408..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           94 a          165 c          117 g          107 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tcgtctcctc tcctcctcac cctgctcatt cactgcacag ggtcctgggc ccagtctgtg
      121 ctgacacagc caccctcagt gtctggggcc ccagggcaga cggtcaccat ctcgtgcact
      181 gggagcagct ccagcattgg aggtgattat gtatcctggt accaacaact cccaggaacg
      241 acccccaaac tcctcatcta tcaaaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggtac ctcagcctcc ctgaccatca ctgggctcca gactgaggat
      361 gaggctgatt actactgcct gtcctatgac agcagcctga gtgctcatta cttcttcggt
      421 cctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCVO01002097             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1104:20164:19798
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002097
VERSION     KCVO01002097.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1104:20164:19798"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    108..438
                     /note="immunoglobulin light chain variable region"
     V_region        108..438
     V_segment       108..403
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <366..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74126.1"
                     /translation="DYYCCSYADTYTFVF"
     J_segment       404..438
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           84 a          157 c          121 g          114 t
ORIGIN      
        1 acatgggggg ctggggtctc agacggcagc gctctcggga catctccacc atggcctggg
       61 ctctgctcct cctcaccctc ctcactcagg gcacaggatc ctgggctcag gctgccctga
      121 ctcagcctcg ctcagtgtct gggtctcctg gacagtcggt caccatctcc tgcactggaa
      181 ccagcagtga catcggtact tataactatg tctcctggta ccaacagcat ccaggcacag
      241 cccccaaact catgattttt gaggtcaatg agcggccctc aggggtctct gatcgcttct
      301 ctggctccaa gtctggcaac acggcctccc tgaccatctc tgggctccag gctgaggacg
      361 aggctgatta ttactgttgc tcatatgcag acacctacac ttttgtgttt ggaggtggca
      421 ccagattgac cgtcctcggt cagcccaagg cttccccctt ggtcactctg ttcccg
//
LOCUS       KCVO01002098             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1115:20398:18280
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002098
VERSION     KCVO01002098.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1115:20398:18280"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74127.1"
                     /translation="DYYCYSMDSSTYLGFF"
     J_segment       389..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           93 a          144 c          123 g          104 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc cctcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccaaaaaa atacgcttat tggttccagc agaagccagg ccagtcccct gtattgatca
      241 tctatgagga caccaaacgg ccctctggga tccctgagag attctctggc tccagctcag
      301 ggacagtggc caccttgact atcagtgggg cccaggtgga ggatgaagct gactactact
      361 gttactcaat ggatagcagt acttatcttg gcttcttcgg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01002099             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:18220:11392
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002099
VERSION     KCVO01002099.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:18220:11392"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74128.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          143 c          140 g           97 t
ORIGIN      
        1 acatgggggg cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gacctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gtgggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga acgattctct ggctccaaat
      301 cagggagcgc cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01002100             327 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:7856:8750
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002100
VERSION     KCVO01002100.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 327)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:7856:8750"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    73..289
                     /note="immunoglobulin light chain variable region"
     V_region        73..289
     V_segment       73..252
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <214..>261
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74129.1"
                     /translation="DYYCYSTDTSGDHRVF"
     J_segment       254..289
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        290..>327
                     /gene="IGLC"
BASE COUNT           61 a          106 c           88 g           72 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacagaagcc aggccagtcc cctgtgttga tcatctatga ggacaccaaa
      121 cggcccgctg ggatccctga gagattctct ggctccagct caggcacagt ggccaccttg
      181 actgtcactg gggcccaggt ggaggatgaa gctgactact actgttactc aacagatacc
      241 agtggtgatc atagggtgtt cggcggaggg acccggctga ccgtcctagg tcagcccaag
      301 gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01002101             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:19191:16225
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002101
VERSION     KCVO01002101.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:19191:16225"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..402
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74130.1"
                     /translation="DYYCSSYADTYTFVF"
     J_segment       403..437
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           79 a          162 c          121 g          113 t
ORIGIN      
        1 acatgggggc tggggtctca gacggcagcg ctctcgggac atctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctcgc tcagtgtctg ggtctcctgg acagtcggtc accatctcct gcactggcac
      181 cagcagtgac atcggtggtt ataactttgt ctcctggtac caacaccatc caggcacagc
      241 ccccaaactc gtgatttatg aggtcactca gcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcagcg cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tactgctcct catatgcaga cacttacact tttgtgttcg gaagtggcac
      421 caagttgacc gtcctcggtc agcccaaggc ttcccccttg gtcactctgt tcccg
//
LOCUS       KCVO01002102             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:19027:12947
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002102
VERSION     KCVO01002102.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:19027:12947"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..450
                     /note="immunoglobulin light chain variable region"
     V_region        117..450
     V_segment       117..410
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74131.1"
                     /translation="DYYCSLWDSRLSSRLF"
     J_segment       418..450
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           94 a          155 c          128 g          111 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctctcctt ctcactctgc tggttcactg cacagggtcc tgggcccagt
      121 ctgtgctgac gcagtcgccc tcagcatctg gggcccccgg gcagagggtc accatctcct
      181 gcactgggac cagctccaac atcggggcga attattatgt ttcctggtac cagcagttcc
      241 caggaacagc ccccaaactc ctcatctatg aaaataataa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtacct cagcctccct gaccatctct ggactccaat
      361 ctgaggatga ggctgattat tactgctcac tatgggatag caggctgagt agtcggttat
      421 tcggcggagg gacccgactg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCVO01002103             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:13206:16017
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002103
VERSION     KCVO01002103.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:13206:16017"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    96..424
                     /note="immunoglobulin light chain variable region"
     V_region        96..424
     V_segment       96..390
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74132.1"
                     /translation="DYYCSSYTSSSTWIF"
     J_segment       391..424
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>464
                     /gene="IGLC"
BASE COUNT           86 a          154 c          118 g          106 t
ORIGIN      
        1 acatgggcag gaggcagcac tctcaggacg tctccaccat ggcctgggct ctgctcctcc
       61 tcaccctcct cactcagggc acaggatcct gggctcaggc tgccctgact cagtctccct
      121 ctgtgtctgg gtctcctgga cagtcggtca ccatttcctg cactggaacc agcagtgaca
      181 ttggtgatta taaccgtgtc tcctggtacc aacagcaccc aggcaaagcc cccaaactca
      241 tgatttatga ggtcagtgat cggccctcag gggtctctga tcgcttctct ggttccaagt
      301 ctggcaacac ggcctccctg atcatctctg ggctccaggc tgaggacgag gctgattatt
      361 actgcagctc atacacaagc agtagcactt ggatattcgg cggagggacc cggctgaccg
      421 tccttggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01002104             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2115:11725:4243
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002104
VERSION     KCVO01002104.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2115:11725:4243"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74133.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          145 c          124 g          101 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctctgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaatac tatgcttatt ggttccagca gaagccaggc cagtcccctg tggcgatcat
      241 ctatgaggac aacaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtcgag gatgaagctg actactactg
      361 ttactcaaca gatagcagtg gtactaatgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01002105             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:9723:18396
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002105
VERSION     KCVO01002105.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9723:18396"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..450
                     /note="immunoglobulin light chain variable region"
     V_region        120..450
     V_segment       120..413
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74134.1"
                     /translation="DYYCGVWDSSLSARLF"
     J_segment       415..450
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        451..>488
                     /gene="IGLC"
BASE COUNT           93 a          156 c          130 g          109 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 gcatggcctg gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtgct gacgcagccg ccctcagtgt ctggggaccc cgggcagagg gtcaccatct
      181 cgtgcactgg gagcagctcc aacattggag gttattttgt atactggtac cagcagttcc
      241 caggaacagc ccccaaactc ctcatctatg acaataataa acgaccctca gggatttctg
      301 accgattctc tggctccaag tctggtacct cagcctccct gaccatcact gggctccagc
      361 ctggggatga ggctgattat tactgcggag tatgggatag cagcctgagt gctcgcttat
      421 tcggaggagg gacccggctg accgtcctag gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCVO01002106             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:12869:16577
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002106
VERSION     KCVO01002106.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12869:16577"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74135.1"
                     /translation="DYYCSSYASSSTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           86 a          155 c          124 g          108 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtaatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccagact gaggacgagg
      361 ctgattatta ctgcagctca tacgcaagca gtagcacttg ggttttcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01002107             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:14550:15778
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002107
VERSION     KCVO01002107.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14550:15778"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..374
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74136.1"
                     /translation="DYYCSSTDSGGNHVF"
     J_segment       378..408
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           88 a          142 c          118 g           98 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatatg
      181 cttattggtt ccaacagaag ccaggccagt cccctgtgct gatcatcaat gaggacagca
      241 agcggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactctcag tggggcccag gtggaggatg aagctgacta ctactgttcc tcaacagata
      361 gcggtggtaa tcatgttttc ggcggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01002108             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:21213:9299
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002108
VERSION     KCVO01002108.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:21213:9299"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..426
                     /note="immunoglobulin light chain variable region"
     V_region        102..426
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74137.1"
                     /translation="DYYCQVWDSRSDHSLL"
     J_segment       393..426
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        427..>464
                     /gene="IGLC"
BASE COUNT           88 a          142 c          137 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgaa ctcactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggaggcaatg
      181 ttggaagtga atatgtccac tggtatcaac agaagccacc gcaggcccct gtggtggtca
      241 tctattataa tactgaccgg ccctcaggga tccctgagcg attctctggc tccaaatcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtagg agtgatcata gtttattggg aggagggacc cggctgaccg
      421 tcctaggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01002109             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:8506:15353
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002109
VERSION     KCVO01002109.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:8506:15353"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..428
                     /note="immunoglobulin light chain variable region"
     V_region        105..428
     V_segment       105..400
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74138.1"
                     /translation="DYFCCSYADTYTFVF"
     J_segment       405..428
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>473
                     /gene="IGLC"
BASE COUNT           83 a          156 c          121 g          113 t
ORIGIN      
        1 acatggggtg gggtctcaga cggcagcgct ctcgggacat ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agcctcgctc agtgtctggg tctcctggac agtcggtcac catctcctgc actggaacca
      181 gcagtgacat cggtggttat aactttgtct cctggtacca acaacatcca ggcacagccc
      241 ccaaactcat gatttatgag gtcaatcagc ggccctcagg ggtctctgat cgcttctctg
      301 gctcaaagtc tggcaacacg gcctccctga ccgtctccgg ggtccaggct gaggacgagg
      361 ctgattattt ctgctgctca tatgcagaca cctacacttt tgttttcgga agtggcacca
      421 ggttgaccgt cgtcggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01002110             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:18889:4610
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002110
VERSION     KCVO01002110.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:18889:4610"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..381
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74139.1"
                     /translation="DYYCQVWDSITDHWVF"
     J_segment       392..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           82 a          156 c          134 g           95 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca caggctctgc ggtctcctat gacctgactc
      121 agccacgctc attgtccgtg tcccccggac acacggccag gctcacctgt gggggagaca
      181 acattggaag taaaagtgta cagtggtacc agcagaagcc accgcaggcc cctgtcctgg
      241 tcatctttgg ttatggcgaa cggccctcag ggatccctga gcgattctct gcctccaact
      301 cacggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt ttgggacagt atcactgatc attgggtctt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01002111             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2117:12635:17018
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002111
VERSION     KCVO01002111.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2117:12635:17018"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-112"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74140.1"
                     /translation="DYYCCSYTISTTWVF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           87 a          152 c          121 g          115 t
ORIGIN      
        1 acatgggggc tggggtctca gaaggcagcg ctctcaggac gtctccacca tggcctggac
       61 tctgctcctc gtcaccctcc tcactcaagg cacaggatcc tgggctcagt ctgccccgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 caacagtgat attgggtatt ataatgctgt gtcttggtac caacagcacc caggcacagc
      241 ccccaaagtc atgatttatg gtgtcagtaa tcggccctca ggggtctctg atcgcttctc
      301 tggctccaag tctggcaaca cggcctccct gaccatctct gggctccagg ctgaggacga
      361 ggctgattat tattgttgtt catatacaat cagtaccact tgggtattcg gcggagggac
      421 ccggctgacc gttctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01002112             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:14656:21332
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002112
VERSION     KCVO01002112.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:14656:21332"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74141.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           87 a          162 c          125 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtag ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgcg
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01002113             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:10594:9622
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002113
VERSION     KCVO01002113.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:10594:9622"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..368
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74142.1"
                     /translation="DYYCYSTDSSGSTGLF"
     J_segment       374..411
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           91 a          142 c          115 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct ctgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaatactatg
      181 cttattggtt ccaacagaag ccaggccagt cccctgtggc gatcatctat gaggacaaca
      241 aacggccctc tgggatccct gagagattct ctggctccag ctcagggaca gtggccactt
      301 tgactatcag tggggcccag gtagaggatg aagctgacta ctactgttac tcaacagata
      361 gcagtggttc tactggctta ttcggaggag ggacccggct gaccgtccta ggtcagccca
      421 aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01002114             491 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:7739:5097
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002114
VERSION     KCVO01002114.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 491)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:7739:5097"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..453
                     /note="immunoglobulin light chain variable region"
     V_region        120..453
     V_segment       120..411
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>425
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74143.1"
                     /translation="IYYCLSYDTSLSGHGLF"
     J_segment       416..453
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        454..>491
                     /gene="IGLC"
BASE COUNT           94 a          165 c          122 g          110 t
ORIGIN      
        1 acatggggga agctctgctt cagctgtggg cacaggaggc agcactcagg acagtctcca
       61 acatggcctc gtctcctctc ctcctcaccc ttctcattca ctgcacaggg tcctgggccc
      121 agtctgtact gacacagcca ccctcactgt ctggggcccc agggcagagg gtcaccatct
      181 cgtgcactgg gagcagctcc aacattggag gttattctat atcctggtgc cagaagttcc
      241 cagaaacgac ccccaacctc ctcgactatc aagatactaa gcgaccctca ggggtttctg
      301 accgattctc tggctccaag tctggtccct cagcctccct gaccatcgct gggctccaga
      361 ctgaggatgg gcctatttat tactgcctgt cgtatgacac cagcctgagt ggtcatggct
      421 tattcggagg aggaacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca
      481 ctctcttccc g
//
LOCUS       KCVO01002115             482 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:5563:6917
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002115
VERSION     KCVO01002115.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 482)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:5563:6917"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..444
                     /note="immunoglobulin light chain variable region"
     V_region        99..444
     V_segment       99..405
                     /gene="IGLV11-87"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>416
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74144.1"
                     /translation="DYYCQVYDSTGVLF"
     J_segment       408..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>482
                     /gene="IGLC"
BASE COUNT           89 a          161 c          124 g          108 t
ORIGIN      
        1 acatgggggg gtctgtggcc tcagaggtaa ccgtgtccac catggccctg actcctctcc
       61 tcctcctgct cctctctcac tgcacaggtt ccctctccca gcctgtgctg actcagccac
      121 cctccctgtc tgcatccccg ggagcatcgg ccagactccc ctgcaccctg agcagtgacc
      181 tcagtgttgg tagtaaaaac atgtactggt accagcagaa gccagggagc gctcccaggt
      241 tattcctgta ctactactcc gactcagaca agcagctggg acctggggtc cccaatcgag
      301 tctctggctc caaggagacc tcaagtaaca cagcgttttt gctcatctct gggctccagc
      361 ctgaggacga ggccgattat tactgtcagg tgtatgacag tactggagtg ttgttcggag
      421 gagggacccg gctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc
      481 cg
//
LOCUS       KCVO01002116             395 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:10581:15004
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002116
VERSION     KCVO01002116.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 395)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 395)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..395
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10581:15004"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    27..353
                     /note="immunoglobulin light chain variable region"
     V_region        27..353
     V_segment       27..321
                     /gene="IGLV2-33"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <285..>329
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74145.1"
                     /translation="DYYCCSYTSGSTWVF"
     J_segment       322..353
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        354..>395
                     /gene="IGLC"
BASE COUNT           75 a          124 c          106 g           90 t
ORIGIN      
        1 acatgggggg cacaggatcc tgggctcagg ctgccttgac tcagcctccc tcagtgtcca
       61 agtctcttgg acagtcggtc accatctcct gcactggaac cagcaatgac attggtggtt
      121 ataatgacgt ctcctggtac cagcagcacg caggcacagc ccccagactc ctaatttatg
      181 atgtcagtaa gcggccctca ggggtctctg atcgcttctc tggctccaag tctggcaaca
      241 cggcctccct gaccatctct gggctccagg ctgaggacga ggctgactat tactgctgct
      301 catatacgag tggaagtact tgggtattcg gcggagggac ccggctgacc gtcttaggtc
      361 agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01002117             480 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:17933:16159
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002117
VERSION     KCVO01002117.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 480)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:17933:16159"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    109..442
                     /note="immunoglobulin light chain variable region"
     V_region        109..442
     V_segment       109..400
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <367..>414
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74146.1"
                     /translation="DYFCSVWDSSLTIYIF"
     J_segment       405..442
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        443..>480
                     /gene="IGLC"
BASE COUNT           88 a          156 c          125 g          111 t
ORIGIN      
        1 acatgggggc ttcagctgtg ggcacaggag gcagcactca ggacagtctc cagcatggcc
       61 tggtctctcc ttctcactct gctggttcac tgcacagggt ccggggccca gcctgtgctg
      121 acgcagccgc cctcagcatc tggggccccc gggcagaggg tcaccatctc ctgcactggg
      181 agcagctcca acatcggggc gggttattct gtatcctggt atcagcagtt cccaggaaca
      241 gcccccaaac tcctcatcta tgaaaataat aagcgaccct caggggtttc tgaccgattc
      301 tctggctcca agtctggtac ctcagcctcc ctgactatca ctggactcca atctgaggat
      361 gaggctgatt atttctgctc tgtctgggat agcagcctga ctatttacat cttcggtgct
      421 gggacccggc tcaccgtcct aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01002118             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:14983:18497
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002118
VERSION     KCVO01002118.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:14983:18497"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74147.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           85 a          155 c          123 g          110 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacactagca gtagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01002119             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:19930:14207
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002119
VERSION     KCVO01002119.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:19930:14207"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74148.1"
                     /translation="DYYCYSTDSSGNHIF"
     J_segment       388..422
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           95 a          145 c          118 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgacgac agtaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gatagcagtg gtaatcacat cttcgctact gggacccggc tcaccgtcct
      421 aggtcagccc aaggcttccc ccacggtcac tctgttcccg
//
LOCUS       KCVO01002120             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:20082:18969
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002120
VERSION     KCVO01002120.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:20082:18969"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74149.1"
                     /translation="DYYCAAWDNSLSGYIF"
     J_segment       409..445
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           95 a          159 c          121 g          108 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg tagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga agagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaactaat agtgtatcct ggtaccagca gctcccagaa
      241 acggctccca aactcctcat ctattataat gatcgacgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cacgtcagcc tccctggcca tcagtgggct ccagaccgag
      361 gatgaggctg attattactg cgcagcatgg gataacagcc tgagcggtta catcttcggt
      421 gctgggaccc ggctcaccgt cctaggtcag cccaaggctt cccccacggt cactctgttc
      481 ccg
//
LOCUS       KCVO01002121             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:16638:19848
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002121
VERSION     KCVO01002121.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:16638:19848"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..427
                     /note="immunoglobulin light chain variable region"
     V_region        104..427
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74150.1"
                     /translation="DYFCCSYADTYTFVF"
     J_segment       404..427
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>472
                     /gene="IGLC"
BASE COUNT           83 a          156 c          121 g          112 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggaaccag
      181 cagtgacatc ggtggttata actttgtctc ctggtaccaa caacatccag gcacagcccc
      241 caaactcatg atttatgagg tcaatcagcg gccctcaggg gtctctgatc gcttctctgg
      301 ctcaaagtct ggcaacacgg cctccctgac cgtctccggg gtccaggctg aggacgaggc
      361 tgattatttc tgctgctcat atgcagacac ctacactttt gttttcggaa gtggcaccag
      421 gttgaccgtc gtcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01002122             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:22265:13220
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002122
VERSION     KCVO01002122.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:22265:13220"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74151.1"
                     /translation="DYYCSSTDSSGNYVF"
     J_segment       392..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           90 a          143 c          125 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttttt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 caatgaggac aacaaacggc cctctgggat ccctgggaga ttctctggct ccagctcagg
      301 gacagtggcc accttgactc tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagtagtg gtaattatgt cttcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01002123             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:15538:12486
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002123
VERSION     KCVO01002123.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:15538:12486"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..444
                     /note="immunoglobulin light chain variable region"
     V_region        115..444
     V_segment       115..408
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74152.1"
                     /translation="DYFCAVWDDSLSGVLF"
     J_segment       409..444
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        445..>483
                     /gene="IGLC"
BASE COUNT           90 a          155 c          128 g          110 t
ORIGIN      
        1 acatgggggc agcttcagct gtgggtacag aaggcaggac tcaggacaat ctccagcatg
       61 gcctggttcc ctctcctcct caccctcctc actcactgtg cagggtcctg ggcccagtct
      121 gtgctgactc agcctccctc agcgtctgag gccgccagga tgagtgtcac catctcctgt
      181 tctggaagca cctccaacat cggaagtaac agtgtgtcct ggtacctgca gctcccggaa
      241 acggctccca aactcctcat ctattataat gatcggcgag cctcaggtgt ctctgaccga
      301 ttctctggct ccaagtctgg cccgtcagcc tccctggcca tcagtgggct cgagaccgaa
      361 gatgaggctg attatttctg cgcagtatgg gatgatagcc tgagcggtgt gttattcgga
      421 ggagggaccc gactgaccgt cctaagtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01002124             526 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:13310:17682
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002124
VERSION     KCVO01002124.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 526)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 526)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:13310:17682"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    158..488
                     /note="immunoglobulin light chain variable region"
     V_region        158..488
     V_segment       158..451
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <413..>460
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74153.1"
                     /translation="DYYCQSYDTRLRAWVF"
     J_segment       452..488
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        489..>526
                     /gene="IGLC"
BASE COUNT          103 a          163 c          144 g          116 t
ORIGIN      
        1 acatggggac tctcagagta tgaagagggg cagggagaga tttggggaag ctctgcttca
       61 gctgtgggca caggaggcag cactcaggac agtctccagc atggcctggt ctcctctcct
      121 cctcaccctt ctcattcact gcacagggtc ctgggcccag tctgtcctga cgcagccgcc
      181 ctcagtgtct ggggcgcccg ggcagagggt caccgtctcc tgcactggga gcagctccaa
      241 cattggagat tattttgtgc agtggtacca acagcttcca ggaacggccc ccaaactcct
      301 catctatgaa aatgataaac ggccctcagg agtttctgat cgattctctg gctcccagtc
      361 tggaacctca gcctccctca ccatcactgg actccagtct gaggatgagg ctgattatta
      421 ctgccagtcc tatgacacca gattgagggc ttgggtattc ggcggaggga cccggctgac
      481 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01002125             296 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:16631:14295
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002125
VERSION     KCVO01002125.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 296)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:16631:14295"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..258
                     /note="immunoglobulin light chain variable region"
     V_region        8..258
     V_segment       8..221
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <183..>230
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74154.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       225..258
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        259..>296
                     /gene="IGLC"
BASE COUNT           63 a           83 c           87 g           63 t
ORIGIN      
        1 acatgggcaa tgttggagat gaatttgtgc actggtacca acagaagcca ccgcaggccc
       61 ctgtggtggt catccattat aatagtgacc ggccctcagg gatccctgag cgattctctg
      121 cctccaaatc agggaacacc gccaccctga ccatcagcgg ggtcgaggcc ggggatgagg
      181 ctgactatta ctgtcaggtg tgggacagta gtagtgatca tagtttattg ggaggaggga
      241 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01002126             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:14892:6521
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002126
VERSION     KCVO01002126.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:14892:6521"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..435
                     /note="immunoglobulin light chain variable region"
     V_region        107..435
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74155.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       402..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>475
                     /gene="IGLC"
BASE COUNT           86 a          156 c          124 g          109 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtgatt ataaccgtgt ctcctggtac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg aggtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacacaag cagtagcact tgggtattcg gcggagggac
      421 ccggctgacc gtccttggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01002127             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:12725:4993
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002127
VERSION     KCVO01002127.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:12725:4993"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..368
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74156.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       372..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           94 a          143 c          113 g           96 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaca tgcattgcca gaaaaatatg
      181 cttattggta ccagcagaaa ccaggccagt cccctatgct gatcatctat gaggacagca
      241 aacggccctc tgggatccct gaaagattct ctggctccag ctcagggact gtggccacct
      301 tgactatcac tggggcccag gtggaggatg aagctgacta ctactgttac tcagcagaca
      361 acagtggtca gggctcattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01002128             469 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:16866:20817
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002128
VERSION     KCVO01002128.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 469)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:16866:20817"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..431
                     /note="immunoglobulin light chain variable region"
     V_region        107..431
     V_segment       107..394
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <356..>403
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74157.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       401..431
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        432..>469
                     /gene="IGLC"
BASE COUNT           89 a          148 c          134 g           98 t
ORIGIN      
        1 acatgggggc tgcctggcct cgggaagcag ccttggcggt gcctcagcca tggccgggac
       61 ccttctcctc ctcggcctcc ttgcttactg cacaggctct gcggtctcct atgaactgac
      121 tcagccaccc tcggtgtcag tgtccccagg acagacggcc aggatcacct gtgggggaga
      181 caaccttgga gataaatatc tacactggta ccaccagaag ccagcgcagg cccctgtgct
      241 ggtcatctac tatgatagtg accggccctc atggatccct gagcgattct ctgggtccaa
      301 gtcagggaac accgccaccc tgaccatcag cggggtcgag gccggggatg aggctgacta
      361 ttactgtcag gtgtgggaca gtaataatga tcatatcttt ttcggaggag ggacccggct
      421 gaccgtccta ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01002129             458 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1101:16147:15515
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002129
VERSION     KCVO01002129.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1101:16147:15515"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..420
                     /note="immunoglobulin light chain variable region"
     V_region        99..420
     V_segment       99..380
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <348..>392
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74158.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       384..420
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        421..>458
                     /gene="IGLC"
BASE COUNT           95 a          143 c          123 g           97 t
ORIGIN      
        1 atgggggtgg gctcaggagg cagagctctg ggtgtctcac catggcctgg attcctctcc
       61 tactccccat cctcactttc tgcacaggct ctgcagcctc ctatgagctg acacagccac
      121 cctcgttgtc agtgtcccca ggacagacgg ccaggatcac ctgctctgga gatgcattgc
      181 cagaaaaata tgcttattgg taccagcaga aaccaggcca gtcccctatg ctgatcatct
      241 gtgaggacag caaacggccc tctgggatcc ctgaaagatt ctctggctcc agctcaggga
      301 cagtggccac cttgactatc actggggccc aggtggagga tgaagctgac tactactgtt
      361 actcagcaga caacagtggt cagggctcat tcggaggagg gacccggctg accgtcctag
      421 gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01002130             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:10521:17267
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002130
VERSION     KCVO01002130.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:10521:17267"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74159.1"
                     /translation="DYYCSSYTSSRTWVF"
     J_segment       400..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           86 a          154 c          124 g          109 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca gtagaacttg ggtgttcggc ggagggaccc
      421 ggctgaccgt ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01002131             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1117:28823:14095
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002131
VERSION     KCVO01002131.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1117:28823:14095"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    120..449
                     /note="immunoglobulin light chain variable region"
     V_region        120..449
     V_segment       120..413
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <375..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74160.1"
                     /translation="DYYCATWDNSLSGVLF"
     J_segment       414..449
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        450..>488
                     /gene="IGLC"
BASE COUNT           99 a          154 c          126 g          109 t
ORIGIN      
        1 acatggggga agcgcagctt cagctgtggg tacagaaggc aggactcagg acaatctcca
       61 gcatggcctg gttccctctc ctcctcaccc tcctcactca ctgtgcaggg tcctgggccc
      121 agtctgtgct gactcagcct ccctcagcgt ctgaggccgc caggaagagt gtcaccatct
      181 cctgttctgg aagcagctcc aatatcggaa gtaatagtgt atcctggtac cagcaactcc
      241 cagaaacggc tcccaaactc ctcatttatt ataatgatcg gcgagcctca ggtgtctctg
      301 accgattctc tggctccaag tctggcacgt cagcctccct ggccatcact gggctccaga
      361 ccgaggatga ggctgattat tactgcgcaa catgggataa tagcctgagc ggtgtgttat
      421 tcggaggagg gacccggctg accgtcctaa gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCVO01002132             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1110:18645:16794
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002132
VERSION     KCVO01002132.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1110:18645:16794"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74161.1"
                     /translation="DYYCYSTDNSGNHRVF"
     J_segment       390..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           95 a          142 c          124 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggctccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac accaaacggc cctctgggat ccttgagaga ttttctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttactcaaca gataacagtg gtaatcatag ggttttcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01002133             348 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:22564:4048
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002133
VERSION     KCVO01002133.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 348)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 348)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..348
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:22564:4048"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..310
                     /note="immunoglobulin light chain variable region"
     V_region        8..310
     V_segment       8..270
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <232..>282
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74162.1"
                     /translation="DYHCFSTDSSGNHRGLF"
     J_segment       274..310
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        311..>348
                     /gene="IGLC"
BASE COUNT           76 a          101 c           96 g           75 t
ORIGIN      
        1 acatgggcgg tgtcagtgtc cccaggacag acggccagga tcacctgctc tggagatgca
       61 ttgccaaaaa aatttgcttc ttggttccag cagaagccag gccagtcccc tgtgctaatc
      121 atctatgacg acagcaaacg gccctctggg atccctgaga gattctctgg ctccagctca
      181 gggacagtgg ccaccttgac tatcattggg gcccaggtgg aggatgaagc tgactaccac
      241 tgtttctcaa cagatagcag tggtaatcat aggggcttat tcggaggagg gacccggctg
      301 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01002134             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1112:23920:12378
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002134
VERSION     KCVO01002134.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1112:23920:12378"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..440
                     /note="immunoglobulin light chain variable region"
     V_region        113..440
     V_segment       113..406
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74163.1"
                     /translation="DYYCGAWDSSLSARLF"
     J_segment       408..440
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        441..>481
                     /gene="IGLC"
BASE COUNT           91 a          154 c          130 g          106 t
ORIGIN      
        1 acatgggggg cttcagctgt gggcacagga ggcagcactc aggacagtct ccagcatggc
       61 ctggtctcct ctcctcctca cccttctcat tcactgcaca gggtcctggg cccagtctgt
      121 gctgacgcag ccgccctcag tgtctgggga ccccgggcag agggtcacca tctcgtgcac
      181 tgggagcagc tccaacattg gaggttattt tgtatactgg taccagcagt tcccaggaac
      241 agcccccaaa ctcctcatct atgacaataa taagcgaccc tcagggattt ctgaccgatt
      301 ctctggctcc aagtctggta cctcagcctc cctgaccatc actgggctcc agcctgggga
      361 tgaggctgat tattactgcg gagcatggga tagtagcctg agtgctcgct tattcggagg
      421 agggacccgg ctgaccgtcc aaggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01002135             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:12910:19339
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002135
VERSION     KCVO01002135.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:12910:19339"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74164.1"
                     /translation="DYYCQVWDSSSDHSLL"
     J_segment       396..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           88 a          143 c          139 g           97 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaga tgaatttgtg cactggtacc aacagaagcc accgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga gcgattctct gcctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc atagtttatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01002136             481 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:5574:16569
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002136
VERSION     KCVO01002136.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 481)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:5574:16569"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    113..443
                     /note="immunoglobulin light chain variable region"
     V_region        113..443
     V_segment       113..405
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <368..>415
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74165.1"
                     /translation="DYYCQSYDSSLSAVLF"
     J_segment       407..443
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        444..>481
                     /gene="IGLC"
BASE COUNT           89 a          155 c          129 g          108 t
ORIGIN      
        1 acatgggggg cttcagctgt gggcacagga ggcagcactc aggacagtct ccagcatggc
       61 ctggtctcct ctcctcctca cccttctcat tcactgcaca gggtcctggg cccagtctgt
      121 gctgacgcag ccgccctcag tgtctggggc gcccgggcag agggtcacca tctcctgcac
      181 tgggagcagt tccaacattg gaggttatta tgtgcagtgg taccagcagc ttccaggaac
      241 ggcccccaaa ctcctcatgt atgaaaataa taagcgaccc tcaggggttt ctgatcgatt
      301 ctctggctcc cagtctggta cctcagcctc cctgaccatc actggactcc agtctgagga
      361 tgaggctgat tattactgcc agtcctatga cagcagcctg agtgccgtgt tattcggagc
      421 agggacccgg ctgaccgtcc taggtcagcc caaggctgcc ccctcggtca ctctcttccc
      481 g
//
LOCUS       KCVO01002137             323 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:4136:17091
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002137
VERSION     KCVO01002137.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 323)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:4136:17091"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..285
                     /note="immunoglobulin light chain variable region"
     V_region        8..285
     V_segment       8..248
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <210..>257
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74166.1"
                     /translation="DYYCYSTDTSGDHRVF"
     J_segment       250..285
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        286..>323
                     /gene="IGLC"
BASE COUNT           68 a           94 c           91 g           70 t
ORIGIN      
        1 acatggggac ggccaggatc acctgctctg gagatgcatt gccaaaaaaa tttgcttttt
       61 ggttccagca gaagccaggc cagtcccctg tgttgatcat ctatgaggac accaaacggc
      121 ccgctgggat ccctgagaga ttctctggct ccagctcagg cacagtggcc accttgactg
      181 tcactggggc ccaggtggag gatgaagctg actactactg ttactcaaca gataccagtg
      241 gtgatcatag ggtgttcggc ggagggaccc ggctgaccgt cctaggtcag cccaaggctg
      301 ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01002138             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2111:20793:9757
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002138
VERSION     KCVO01002138.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2111:20793:9757"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74167.1"
                     /translation="DYYCYSTDSSGTNGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          143 c          125 g          102 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctctgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggtcaggatc acctgctctg gaaatgcatt
      181 gccagaatac tatgcttatt ggttccagca gaagccaggc cagtcccctg tggcgatcat
      241 ctatgaggac aacaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtagag gatgaggctg actactactg
      361 ttactcaaca gatagcagtg gtactaatgg cttattcgga ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01002139             468 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:7924:11189
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002139
VERSION     KCVO01002139.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 468)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:7924:11189"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..430
                     /note="immunoglobulin light chain variable region"
     V_region        106..430
     V_segment       106..393
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <355..>402
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74168.1"
                     /translation="DYYCQVWDSSSDHILF"
     J_segment       396..430
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        431..>468
                     /gene="IGLC"
BASE COUNT           87 a          146 c          137 g           98 t
ORIGIN      
        1 acatggggca gcctggcctc gggaagcagc cttggcggtg cctcagccat ggccgggacc
       61 cttctcctcc tcggcctcct tgcttactgc acaggctctg cggtctccta tgagttgact
      121 cagccaccct cggtgtcagt gtccccagga cagacggcca ggatcacctg tgggggagac
      181 aaccttggag ataaatatgt acactggtac cagcagaagc caccgcgggc ccctgtgctg
      241 gtcatctact atgatagtga ccggccctca tggatccctg agcgattctc tgggtccaaa
      301 tcagggatca ccgccaccct gaccatcagc ggggtcgagg ccggggatga ggctgactat
      361 tactgtcagg tgtgggacag tagtagtgat catatcttat tcggaggagg gacccggctg
      421 accgtcctag gtcagcccaa ggctgccccc tcggtcactc tcttcccg
//
LOCUS       KCVO01002140             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:14034:10343
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002140
VERSION     KCVO01002140.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:14034:10343"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    97..427
                     /note="immunoglobulin light chain variable region"
     V_region        97..427
     V_segment       97..390
                     /gene="IGLV1-75"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74169.1"
                     /translation="DYYCAVWDDSLSGVLF"
     J_segment       391..427
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>465
                     /gene="IGLC"
BASE COUNT           90 a          152 c          120 g          103 t
ORIGIN      
        1 acatggggac agaaggcagg actcaggaca atctccagca tggcctggtt ccctctcctc
       61 ctcaccctcc tcactcactg tgcagggtcc tgggcccagt ctgtgctgac tcagcctccc
      121 tcagcgtctg aggccgccag gaagagtgtc accatctcct gttctggaag cacctccaac
      181 atcggaagta acagtgtgtc ctggtacctg cagctcccag aaacggctcc caaactcctc
      241 atctattata atgatcggcg agcctcaggt gtctctgacc gattctctgg ctccaagtct
      301 ggcccgtcag cctccctggc catcagtggg ctcgagaccg aagatgaggc tgattattac
      361 tgcgcagtat gggatgatag cctgagcggt gtgttattcg gaggaggcac ccgactgacc
      421 gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01002141             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:18767:10590
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002141
VERSION     KCVO01002141.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:18767:10590"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..433
                     /note="immunoglobulin light chain variable region"
     V_region        105..433
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74170.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       400..433
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>473
                     /gene="IGLC"
BASE COUNT           86 a          155 c          123 g          109 t
ORIGIN      
        1 acatggggtg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 gcagtgacat tggtgattat aaccgtgtct cctggtacca acagcaccca ggcaaagccc
      241 ccaaactcat gatttatgag gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacacaagca gtagcacttg ggtattcggc ggagggaccc
      421 ggctgaccgt ccttggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01002142             449 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:26012:10821
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002142
VERSION     KCVO01002142.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 449)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:26012:10821"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..411
                     /note="immunoglobulin light chain variable region"
     V_region        87..411
     V_segment       87..373
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>383
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74171.1"
                     /translation="DYYCYSRDSSENQSVF"
     J_segment       379..411
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        412..>449
                     /gene="IGLC"
BASE COUNT           96 a          135 c          117 g          101 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccctcc
       61 tcactttctg cacaggctct gcagcctcct atgagctgac acagccaccc tcggtgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca aaaaaatatg
      181 tatattggtt ccagcagaag ccaggccagt cccctgtgtt gatcatctat gaggacaaca
      241 aacggccctc tgggattcct gagagattct ctggctccag ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aaggtgacta ctactgttac tcaagagata
      361 gtagtgaaaa tcagagcgtc ttcggtgctg ggacccggct cagcgtccta ggtcagccca
      421 aggcttcccc cacggtcact ctgttcccg
//
LOCUS       KCVO01002143             302 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1118:25561:9893
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002143
VERSION     KCVO01002143.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 302)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1118:25561:9893"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    6..264
                     /note="immunoglobulin light chain variable region"
     V_region        6..264
     V_segment       6..227
                     /gene="IGLV3-27"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <189..>236
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74172.1"
                     /translation="DYYCQVWDSSSDHPIF"
     J_segment       230..264
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        265..>302
                     /gene="IGLC"
BASE COUNT           59 a           85 c           90 g           68 t
ORIGIN      
        1 acatgggggg agacatcgtt ggaagtgaat atgttcactg gtatcagcag aagtcagcgc
       61 aggcccctgt ggtggtcatc tattattatt ctgaccggcc ctcagggatc cctgagcgat
      121 tctctggctc caaatcaggg aggatcgcca ccctgaccat cagcggggtc gaggccgggg
      181 atgaggctga ctactactgt caggtgtggg acagtagtag tgatcatccc atcttcggtg
      241 ctgggacccg gctcaccgtc ctaggtcagc ccaaggcttc ccccacggtc actctgttcc
      301 cg
//
LOCUS       KCVO01002144             476 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:6306:15330
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002144
VERSION     KCVO01002144.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 476)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:6306:15330"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    114..438
                     /note="immunoglobulin light chain variable region"
     V_region        114..438
     V_segment       114..400
                     /gene="IGLV3-23"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>410
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74173.1"
                     /translation="DYYCQVWDSSSKYMIF"
     J_segment       406..438
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        439..>476
                     /gene="IGLC"
BASE COUNT           92 a          152 c          137 g           95 t
ORIGIN      
        1 acatggggac ctgccctgtc tgggtctcag gaggcagcat tgacggtgcc tcagccatgg
       61 cctggaccct tctcctcctc ggcctcctcg ctcactgcac aggctctgcg acctcctatg
      121 acctgactca ggcaccatcg gtgtcagcgg ccccaggtca gacggccagg atcacctgtg
      181 ggggagacaa cattggaggt tacagtgtgc actggtaccg gcagaagcca ccccaggccc
      241 ctgtactggt catctatgct gatagcaagc ggccctcagg tatccctgag cgattctctg
      301 gctccaactc agggaacacc gccaccctga ccatcagcag ggtcgaggcc ggggatgagg
      361 ctgattacta ctgtcaggtg tgggacagta gtagtaaata tatgatattc ggaggaggga
      421 cccggctgac cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01002145             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:16233:6633
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002145
VERSION     KCVO01002145.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:16233:6633"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74174.1"
                     /translation="DYHCYSTDDSGYHWVF"
     J_segment       389..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           93 a          143 c          127 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tacgcttatt ggttccagca gaagccaggc cagtcccctg tggtgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actaccactg
      361 ttactcaaca gatgacagtg gttatcattg ggtattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01002146             485 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:12241:4745
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002146
VERSION     KCVO01002146.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:12241:4745"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..445
                     /note="immunoglobulin light chain variable region"
     V_region        117..445
     V_segment       117..408
                     /gene="IGLV1-50"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <372..>419
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74175.1"
                     /translation="DYYCQSYDSGLSGLLF"
     J_segment       414..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>485
                     /gene="IGLC"
BASE COUNT           86 a          155 c          129 g          115 t
ORIGIN      
        1 acatgggggc tctgcttcag ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctggtc tcctctcctc ctcacccttc tcattcactg cacagggtct tgggcccagt
      121 ctgtgctgac gcagccgccc tcagtgtctg gggcgcccgg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggagatt attatgtgca gtggtaccag cagcttccag
      241 gaacggcccc caaacttctc atctatgaaa gttataagcg accctcaggg gtttctgatc
      301 gattctctgg ctccccgtct ggtacctcag cctccctgac catcactgga ctccagtctg
      361 aggatgaggc tgattattac tgccagtcct atgacagcgg cctgagtggt cttttattcg
      421 gaggagggac ccgactgatc gtcctgggtc agcccaaggc tgccccctcg gtcactctct
      481 tcccg
//
LOCUS       KCVO01002147             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:12474:3021
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002147
VERSION     KCVO01002147.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:12474:3021"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..387
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74176.1"
                     /translation="DYYCYSMDSSGTQSIF"
     J_segment       391..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           91 a          143 c          126 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaag tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcagacggc cctctgggat ccctgagaga ttctctgcct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccagggggag gatgaagctg actactactg
      361 ttattcaatg gatagcagtg gtactcagag catcttcggt gttgggaccc ggctcaccgt
      421 cctaggtcag cccaaggctt cccccacggt cactctgttc ccg
//
LOCUS       KCVO01002148             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1119:14432:14830
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002148
VERSION     KCVO01002148.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1119:14432:14830"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74177.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           83 a          162 c          120 g          108 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac cctttcctgc actggaacca
      181 gcagtgacat tggtggttat aaccgtgtct cctggtacca acaccaccca ggcaaagccc
      241 ccaaactcat gatttatgac gtcagtgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca tacgcaagca cttccacttg gctattcggc ggagggaccc
      421 gcctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01002149             475 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2106:11499:15692
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002149
VERSION     KCVO01002149.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 475)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2106:11499:15692"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..437
                     /note="immunoglobulin light chain variable region"
     V_region        107..437
     V_segment       107..401
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>409
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74178.1"
                     /translation="DYYCSSYASTTTWLF"
     J_segment       402..437
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        438..>475
                     /gene="IGLC"
BASE COUNT           85 a          163 c          119 g          108 t
ORIGIN      
        1 acatgggggc tgggatctca ggaggcagca ctctcaggac gtctccacca tggcctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagtctccc tctgtgtctg ggtctcctgg acagtcggtc accatttcct gcactggaac
      181 cagcagtgac attggtggtt ataaccgtgt ctcctcctac caacagcacc caggcaaagc
      241 ccccaaactc atgatttatg acgtcagtga tcggccctca ggggtctctg atcgcttctc
      301 tggttccaag tctggcaaca cggcctccct gatcatctct gggctccagg ctgaggacga
      361 ggctgattat tactgcagct catacgcaag cactaccact tggctattcg gcggagggac
      421 ccgcctgacc gtcctaggtc agcccaaggc tgccccctcg gtcactctct tcccg
//
LOCUS       KCVO01002150             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1116:20477:10524
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002150
VERSION     KCVO01002150.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1116:20477:10524"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    107..433
                     /note="immunoglobulin light chain variable region"
     V_region        107..433
     V_segment       107..402
                     /gene="IGLV2-21"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <365..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74179.1"
                     /translation="DYFCSSYTGSITLF"
     J_segment       403..433
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        434..>472
                     /gene="IGLC"
BASE COUNT           87 a          158 c          118 g          109 t
ORIGIN      
        1 acatgggggc tggggtctca ggaggcagcg ctctcaggac gtctccacca tggtctgggc
       61 tctgctcctc ctcaccctcc tcactcaggg cacaggatcc tgggctcagg ctgccctgac
      121 tcagcctccc tctgtgtctg ggtctcctgg acagtcggtc accatctcct gcactggaac
      181 cagcagtgac atcggtggtt ataactatgt ctcctggtac caacgacacc caggcaaagc
      241 ccccaaactc atgatttatg atgtcaataa gcggccctca ggggtctctg atcgcttctc
      301 tggctccaaa tctggcaaca cggcctccct gaccatctct gggctccagt ctgaggatga
      361 ggctgattat ttctgcagct catatacagg cagcatcact ttattcggag gagggacccg
      421 gctgaccgtc ctacgtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01002151             461 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:15877:22204
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002151
VERSION     KCVO01002151.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:15877:22204"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..423
                     /note="immunoglobulin light chain variable region"
     V_region        102..423
     V_segment       102..386
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>395
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74180.1"
                     /translation="DYYCYSADSSGNGLF"
     J_segment       387..423
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        424..>461
                     /gene="IGLC"
BASE COUNT           95 a          139 c          127 g          100 t
ORIGIN      
        1 acatgggggg tgggctcagg aggcagagct ctgggtgtct caccatggcc tggattcctc
       61 tcctactccc catcctcact ttctgcacag gctctgcagc ctcctatgag ctgacacagc
      121 caccctcgtt gtcagtgtcc ccaggacaga cggccaggat cacctgctct ggagatgcat
      181 tgccagaaaa atatgcgtat tggtatcagc agaaaccagg ccagtcccct gtgcatatca
      241 tctatgagga cagcaagcgg ccctctggga tccctgagag attctctggc tccagctcag
      301 ggacagtggc caccttgact atcagtgggg cccaggtgga ggatgaagct gactactact
      361 gttactcagc agacagtagt ggtaatggct tattcggagg agggacccgg ctgaccgtcc
      421 taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01002152             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2118:15126:4577
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002152
VERSION     KCVO01002152.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2118:15126:4577"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..399
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74181.1"
                     /translation="HYYCCSYADTYTFVF"
     J_segment       400..434
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           78 a          161 c          120 g          113 t
ORIGIN      
        1 acatgggggg ggtctcagac ggcagcgctc tcgggacatc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatccttg gctcaggctg ccctgactca
      121 gcctcgctca gtgtctgggt ctcctggaca gtcggtcacc atctcctgca ctggcaccag
      181 cagtgacatc ggtggttata actttgtctc ctggtaccaa caccatccag gcacagcccc
      241 caaactcgtg atttatgagg tcactcagcg gccctcgggg gtctctgatc gcttctctgg
      301 ctccaagtct ggcaacgcgg cctccctgac catctctggg ctccaggctg aggacgaggc
      361 tcattattac tgctgctcat atgcagacac ttacactttt gtgttcggag gtggcaccaa
      421 gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc actctgttcc cg
//
LOCUS       KCVO01002153             488 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2114:14462:16453
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002153
VERSION     KCVO01002153.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 488)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2114:14462:16453"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    117..448
                     /note="immunoglobulin light chain variable region"
     V_region        117..448
     V_segment       117..408
                     /gene="IGLV1-71"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <372..>422
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74182.1"
                     /translation="DYYCQSSDTSLNEHVLF"
     J_segment       413..448
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        449..>488
                     /gene="IGLC"
BASE COUNT           96 a          162 c          120 g          110 t
ORIGIN      
        1 acatgggggc tctgcttcat ctgtgggcac aggaggcagc actcaggaca gtctccagca
       61 tggcctcgtc tcctctcctc ctcacccttc tcattcactg cacagggtcc tgggcccagt
      121 ctgtgctgac acagccgccc tcagtgtctg gggccccagg gcagagggtc accatctcct
      181 gcactgggag cagctccaac attggaggtt attatgtata ctggtaccag caactcccag
      241 gaatggcccc caaactcctc atctatgaca ataataagcg accctcaggg gtttctgacc
      301 gattctctgg ctccaagtct ggtacctcag cctccctgac catcactggg ctccagactg
      361 aggatgaggc tgattattac tgccaatcct ctgacaccag cctaaatgag catgtgttat
      421 tcggaggagg gacccggctg accgtcctcg gtcagcccaa ggctgccccc tcggtcactc
      481 tcttcccg
//
LOCUS       KCVO01002154             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1113:6755:8554
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002154
VERSION     KCVO01002154.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1113:6755:8554"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74183.1"
                     /translation="DYYCQVWDSGHDHVFF"
     J_segment       399..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           87 a          146 c          138 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca caggctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 accttggaga taaatatgta cactggtacc agcagaagcc agcgcaggcc cctgtgctgg
      241 tcatctacta tgatagtgac cggccctcac ggatcactga gcgattctct gggtccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt ggtcatgatc atgtcttttt cggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01002155             470 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2108:24769:3670
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002155
VERSION     KCVO01002155.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 470)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2108:24769:3670"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    99..432
                     /note="immunoglobulin light chain variable region"
     V_region        99..432
     V_segment       99..392
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <357..>404
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74184.1"
                     /translation="DYYCSLWDSRLSSRVF"
     J_segment       397..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>470
                     /gene="IGLC"
BASE COUNT           91 a          149 c          125 g          105 t
ORIGIN      
        1 acatgggggg ggcacaggag gcagcactca ggacagtctc cagcatggcc tggtctctcc
       61 ttctcactct gctggttcac tgcacagggt cctgggccca gtctgtgctg acgcagccgc
      121 cctcagcatc tggggccccc gggcagaggg tcaccatctc ctgcactggg accagctcca
      181 acatcggggc gaattattat gtttcctggt accagcagtt cccaggaaca gcccccaaac
      241 tcctcatcta tgaaaataat aagcgaccct caggggtttc tgaccgattc tctggctcca
      301 agtctggtac ctcagcctcc ctgaccatct ctggactcca atctgaggat gaggctgatt
      361 attattgctc actatgggat agcaggctga gtagtcgggt attcggcgga gggacccgat
      421 tgaccgtcct aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01002156             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2109:9452:19650
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002156
VERSION     KCVO01002156.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2109:9452:19650"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    106..429
                     /note="immunoglobulin light chain variable region"
     V_region        106..429
     V_segment       106..380
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74185.1"
                     /translation="DYYCQVRDSYSDQWVF"
     J_segment       393..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           89 a          147 c          141 g           90 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gctcactgca caggctctgc ggtcgcctat gagctgactc
      121 agccacgctc agtttccgtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 acattggaag taaaagtgta cagtggtacc aacagaagcc accgcaggcc cctgtactgg
      241 tcatctatgg tgatagcgag cggccctcag ggatccctga gcgattctct ggctccaact
      301 cagggaacac cgccaccctg accattagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gcgggacagt tacagtgatc aatgggtatt cggcggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01002157             274 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:19465:16167
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002157
VERSION     KCVO01002157.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 274)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 274)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..274
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:19465:16167"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    7..236
                     /note="immunoglobulin light chain variable region"
     V_region        7..236
     V_segment       7..200
                     /gene="IGLV5-53"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <167..>208
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74186.1"
                     /translation="DYHCMIRHNNAYIF"
     J_segment       201..236
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        237..>274
                     /gene="IGLC"
BASE COUNT           58 a           87 c           67 g           62 t
ORIGIN      
        1 acatgggcag aagccaggga gtcctccccg gtatcttctg aactaccaca cagactcaga
       61 gaagcaccag ggatctggag tccccagccg cttctctgga tccaaggata cttcggccaa
      121 tgcaggcttt ttactcatct ctgggctcca gtctgaggat gaggctgact atcactgtat
      181 gattcggcac aacaatgctt acatcttcgg tgctgggacc cggctcaccg tcctaggtca
      241 gcccaaggct tcccccacgg tcactctgtt cccg
//
LOCUS       KCVO01002158             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2104:18158:13739
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002158
VERSION     KCVO01002158.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2104:18158:13739"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74187.1"
                     /translation="DYYCSSTDSRDNHRVF"
     J_segment       390..425
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           94 a          141 c          128 g          100 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccagaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttttctggct ccagctcagg
      301 gacagtggcc acgttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 ttcctcaaca gatagcaggg ataatcatag ggtattcggc ggagggaccc ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01002159             312 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:25605:5614
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002159
VERSION     KCVO01002159.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 312)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 312)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:25605:5614"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    8..274
                     /note="immunoglobulin light chain variable region"
     V_region        8..274
     V_segment       8..239
                     /gene="IGLV2-29"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="02"
     CDS             <202..>246
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74188.1"
                     /translation="DYYCCSYAGRFTFVF"
     J_segment       240..274
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        275..>312
                     /gene="IGLC"
BASE COUNT           61 a           95 c           80 g           76 t
ORIGIN      
        1 acatggggca ctgggaccag cagtgacatc ggtggttata actttgtctc ctggtaccaa
       61 cagcatgcag gcacagcccc caaactcatg atttatgagg tcagtaagcg gccctcaggg
      121 gtctctgatc gcttctctgg ctccaagtcc ggcaacacgg cctccctgac catctctggg
      181 ctccaggctg aggacgacac tgattattac tgctgctcat atgcaggcag gttcactttt
      241 gtgttcggaa gtggcaccaa gttgaccgtc ctcggtcagc ccaaggcttc ccccttggtc
      301 actctgttcc cg
//
LOCUS       KCVO01002160             465 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1107:19119:10719
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002160
VERSION     KCVO01002160.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 465)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1107:19119:10719"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..425
                     /note="immunoglobulin light chain variable region"
     V_region        103..425
     V_segment       103..390
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <352..>399
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74189.1"
                     /translation="DYYCQVWDFSGDHNIF"
     J_segment       392..425
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>465
                     /gene="IGLC"
BASE COUNT           90 a          149 c          128 g           98 t
ORIGIN      
        1 acatggggct gggcctcagg aggcagcatt gacggtgcct cagccatgac ctggactttt
       61 ctcctcctcg gcctccttgc ttactgcaca ggctctgcgg cctcctctga actgactcag
      121 ccaccctcgg tgtcagtgtc cccaggacag acggccagaa tcacctgtgg gagagacaac
      181 attggaaata aaaatgtgca ctggtaccag cagcggccac cgcgggcccc tgtactggtc
      241 atctattatg ataccgagcg gccctcaggg atccctgagc gattctctgg ctccacatca
      301 gggaacaccg ccaccctgac catcagcggg gtcgaggccg gggatgaggc tgactattac
      361 tgtcaggtgt gggactttag tggtgatcat aacatcttcg atgctgggac ccggctcacc
      421 gtcctcggtc agcccaaggc ttcccccacg gtcactctgt tcccg
//
LOCUS       KCVO01002161             473 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2119:12492:19543
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002161
VERSION     KCVO01002161.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2119:12492:19543"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..435
                     /note="immunoglobulin light chain variable region"
     V_region        105..435
     V_segment       105..399
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <363..>407
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74190.1"
                     /translation="DYYCSSFASSSTWVF"
     J_segment       400..435
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        436..>473
                     /gene="IGLC"
BASE COUNT           81 a          155 c          125 g          112 t
ORIGIN      
        1 acatgggggg ggatctcagg aggcagcact ctcaggacgt ctccaccatg gcctgggctc
       61 tgctcctcct caccctcctc actcagggca caggatcctg ggctcaggct gccctgactc
      121 agtctccctc tgtgtctggg tctcctggac agtcggtcac catttcctgc actggaacca
      181 ccagtgacat tggtggtttt aaccgtgtct cctggtacca acagcaccca ggcaaggccc
      241 ccaaactcat gatttttgag gtcaatgatc ggccctcagg ggtctctgat cgcttctctg
      301 gttccaagtc tggcaacacg gcctccctga tcatctctgg gctccaggct gaggacgagg
      361 ctgattatta ctgcagctca ttcgcaagca gtagtacttg ggttttcggc ggagggaccc
      421 ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01002162             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2102:8758:15890
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002162
VERSION     KCVO01002162.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2102:8758:15890"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..429
                     /note="immunoglobulin light chain variable region"
     V_region        105..429
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74191.1"
                     /translation="DYYCQVWDSSSDHCVL"
     J_segment       397..429
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>467
                     /gene="IGLC"
BASE COUNT           91 a          142 c          138 g           96 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagactctgc ggtctcctat gacctgactc
      121 aaccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggagaca
      181 atgttggaag tgaatatgtg cactggtacc aacagaaacc agcgcaggcc cctgtggtgg
      241 tcatccatta taatagtgac cggccctcag ggatccctga gcgattctct ggctccaaat
      301 cagggaacac cgccaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt agtagtgatc attgtgtatt gggaggaggg acccggctga
      421 ccgtcctagg tcagcccaag gctgccccct cggtcactct cttcccg
//
LOCUS       KCVO01002163             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2105:21269:8018
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002163
VERSION     KCVO01002163.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2105:21269:8018"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..428
                     /note="immunoglobulin light chain variable region"
     V_region        101..428
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74192.1"
                     /translation="DYYCYSTDNYNYHRVFF"
     J_segment       398..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           94 a          144 c          122 g          106 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tggcacagcc
      121 accctcggta tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcttt
      181 gccagaaaaa tttgcttatt ggttccagca gaagccaggc cagtcccctg tactgatcat
      241 ctatgaggac agcaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggcg gatgaagctg actactactg
      361 ttactcaaca gataactata attatcatag ggtcttcttc ggaggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01002164             460 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1102:18856:14668
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002164
VERSION     KCVO01002164.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1102:18856:14668"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..422
                     /note="immunoglobulin light chain variable region"
     V_region        101..422
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>394
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74193.1"
                     /translation="DYYCHSLDTSGNDVF"
     J_segment       392..422
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        423..>460
                     /gene="IGLC"
BASE COUNT           91 a          142 c          124 g          103 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tttgcttact ggttccagca gaagccaggc cagtcccctg tggtgatcat
      241 ctatgaggac accaaacggc cctctgggat ccctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtggag gatgaagctg actactactg
      361 tcattcatta gataccagtg gtaatgatgt tttcggcgga gggacccggc tgaccgtcct
      421 aggtcagccc aaggctgccc cctcggtcac tctcttcccg
//
LOCUS       KCVO01002165             483 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:11104:11983
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002165
VERSION     KCVO01002165.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 483)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:11104:11983"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    115..445
                     /note="immunoglobulin light chain variable region"
     V_region        115..445
     V_segment       115..406
                     /gene="IGLV1-70"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <370..>417
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74194.1"
                     /translation="DYYCGAWDSSLSGRLF"
     J_segment       410..445
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        446..>483
                     /gene="IGLC"
BASE COUNT           89 a          156 c          130 g          108 t
ORIGIN      
        1 acatggggtc tgcttcagct gtgggcacag gaggcagcac tcaggacagt ctccagcatg
       61 gcctggtctc ctctcctcct cacccttctc attcactgca cagggtcctg ggcccagtct
      121 gtgctgacgc agccgccctc agtgtctggg gaccccgggc agagggtcac catctcgtgc
      181 actgggagca gctccaacat tggaggtttt cttgtatact ggtaccagca gttcccagga
      241 acagccccca aactcctcat ctatgacaat aataagcgac cctcagggat ttctgaccga
      301 ttctctggct ccaagtctgg tacctcagcc tccctgacca tcactgggct ccagcctggg
      361 gatgaggctg attattactg cggagcatgg gatagcagcc tgagtggtcg cttattcgga
      421 ggagggaccc ggctgaccgt cctaggtcag cccaaggctg ccccctcggt cactctcttc
      481 ccg
//
LOCUS       KCVO01002166             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:20103:5236
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002166
VERSION     KCVO01002166.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:20103:5236"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..428
                     /note="immunoglobulin light chain variable region"
     V_region        104..428
     V_segment       104..391
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74195.1"
                     /translation="DYYCQVWDSNSDHIFF"
     J_segment       398..428
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           86 a          147 c          136 g           97 t
ORIGIN      
        1 acatgggagc ctggcctcgg gaagcagcct tggcggtgcc tcagccatgg ccgggaccct
       61 tctcctcctc ggcctccttg cttactgcac aggctctgcg gtctcctatg agctgactca
      121 gccaccctcg gtgtcagtgt ccccaggaca gacggccagg atcacctgtg ggggagacaa
      181 ccttggagat aaatatctac actggtacca gcagaagcca gcgcaggccc ctgtgctggt
      241 catctactat gctagtgacc ggccctcatg gatccctgag cgattctctg ggtccaagtc
      301 agggaacacc gtcaccctga ccatcagcgg ggtcgaggcc ggggatgagg ctgactatta
      361 ctgtcaggtg tgggacagca atagtgatca tatctttttc gggggaggga cccggctgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01002167             489 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1109:10464:16929
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002167
VERSION     KCVO01002167.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 489)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1109:10464:16929"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    130..451
                     /note="immunoglobulin light chain variable region"
     V_region        130..451
     V_segment       130..411
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <379..>423
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74196.1"
                     /translation="DYYCYSADNSGQGSF"
     J_segment       415..451
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        452..>489
                     /gene="IGLC"
BASE COUNT          104 a          151 c          133 g          101 t
ORIGIN      
        1 acatggggaa gagaagccta gggagcccag ctgtgctgtg ggctcaggag gcagagctct
       61 gggtgtctca ccatggcctg gattcctctc ctactcccca tcctcacttt ctgcacaggc
      121 tctgcagcct cctatgagct gacacagcca ccctcgttgt cagtgtcccc aggacagacg
      181 gccaggatca cctgctctgg agatgcattg ccagaaaaat atgcttattg gtaccagcag
      241 aaaccaggcc agtcccctat gctgatcatc tgtgaggaca gcaaacggcc ctctgggatc
      301 cctgaaagat tctctggctc cagctcaggg acagtggcca ccttgactat cactggggcc
      361 caggtggagg atgaagctga ctactactgt tactcagcag acaacagtgg tcagggctca
      421 ttcggaggag ggacccggct gaccgtccta ggtcagccca aggctgcccc ctcggtcact
      481 ctcttcccg
//
LOCUS       KCVO01002168             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2113:7726:12774
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002168
VERSION     KCVO01002168.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2113:7726:12774"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74197.1"
                     /translation="DYYCYSTRSSGYHGLF"
     J_segment       389..425
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           92 a          142 c          124 g          105 t
ORIGIN      
        1 acatgggggt gggctcagga ggcagagctc tgggtgtctc accatggcct ggattcctct
       61 cctactcccc ctcctcactt tctgcacagg ctctgcagcc tcctatgagc tgacacagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgctctg gagatgcatt
      181 gccaaaaaaa tatgcttatt ggttccagca gaagccaggc cagtcccctg tgctgatcat
      241 ctatgaggac agcaaacggc cctctgggat ctctgagaga ttctctggct ccagctcagg
      301 gacagtggcc accttgacta tcagtggggc ccaggtgcag gatgaagctg actactactg
      361 ttactcaact cgtagcagtg gttatcatgg cttattcgga ggagggacct ggctgaccgt
      421 cctaggtcag cccaaggctg ccccctcggt cactctcttc ccg
//
LOCUS       KCVO01002169             467 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1114:18458:8189
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002169
VERSION     KCVO01002169.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 467)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1114:18458:8189"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    105..427
                     /note="immunoglobulin light chain variable region"
     V_region        105..427
     V_segment       105..392
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <354..>401
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74198.1"
                     /translation="DYYCQVWDSITDHSIF"
     J_segment       395..427
                     /gene="IGLJ1-6"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        428..>467
                     /gene="IGLC"
BASE COUNT           86 a          149 c          134 g           98 t
ORIGIN      
        1 acatggggag cctggcctcg ggaagcagcc ttggcggtgc ctcagccatg gccgggaccc
       61 ttctcctcct cggcctcctt gcttactgca cagtctctgc ggtctcctat gagctgactc
      121 agccaccctc ggtgtcagtg tccccaggac agacggccag gatcacctgt gggggggaca
      181 acattggaac tgaatatgtg cactggtacc agcagaagcc accgcaggcc cctgtggtgg
      241 tcatctatta taatactgac cggccctcag ggatccctga gcgattctca ggctccaaat
      301 cagggaacac cggcaccctg accatcagcg gggtcgaggc cggggatgag gctgactatt
      361 actgtcaggt gtgggacagt attactgatc attccatctt cggtgctggg acccggctca
      421 ccgtcctggg tcagcccaag gcttccccca cggtcactct gttcccg
//
LOCUS       KCVO01002170             471 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2110:16480:9927
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002170
VERSION     KCVO01002170.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 471)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2110:16480:9927"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    103..429
                     /note="immunoglobulin light chain variable region"
     V_region        103..429
     V_segment       103..397
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <361..>405
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74199.1"
                     /translation="DYYCSSYASTSTWLF"
     J_segment       398..429
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        430..>471
                     /gene="IGLC"
BASE COUNT           86 a          155 c          121 g          109 t
ORIGIN      
        1 acatgggggg atctcaggag gcagcactct caggacgtct ccaccatggc ctgggctctg
       61 ctcctcctca ccctcctcac tcagggcaca ggatcctggg ctcaggctgc cctgactcag
      121 tctccctctg tgtctgggtc tcctggacag tcggtcacca tttcctgcac tggaaccagc
      181 agtgacattg gttattataa ccgtgtctcc tggtaccaac agcacccagg caaagccccc
      241 aaactcatga tttatgaggt cagtgatcgg ccctcagggg tctctgatcg cttctctggt
      301 tccaagtctg gcaacacggc ctccctgatc atctctgggc tccaggctga ggacgaggct
      361 gattattact gcagctcata tgcaagcact agcacttggc tattcggcgg agggacccgg
      421 ctgaccgtcg taggtcagcc caaggctgcc ccctcggtca ctctcttccc g
//
LOCUS       KCVO01002171             459 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:22639:3319
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002171
VERSION     KCVO01002171.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 459)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:22639:3319"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    100..421
                     /note="immunoglobulin light chain variable region"
     V_region        100..421
     V_segment       100..381
                     /gene="IGLV3-31"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <349..>393
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74200.1"
                     /translation="DYYCQVWDSSSDVLF"
     J_segment       384..421
                     /gene="IGLJ3-4"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        422..>459
                     /gene="IGLC"
BASE COUNT           86 a          137 c          139 g           97 t
ORIGIN      
        1 acatgggggg cctcgggaag cagccttggc ggtgcctcag ccatggccgg gacccttctc
       61 ctcctcggcc tccttgctca ctgcacagag tttgtggtct cctatgaatt gactcagcca
      121 cgctcagtgt ccgtgtcccc aggacagacg gccaggatca cctgtggggg agacagcatt
      181 ggaagtagaa gtgtgcagtg gtatcagcag aagccaccgc aggcccttct actggtcatc
      241 tatgctgata gcgaacggcc ctcagggatc cctgagcgat tctctggctc caatttaggg
      301 aacaccgcca ccctgaccat cagcggcgtc gaggccgggg atgaggctga ctattactgt
      361 caggtgtggg acagtagtag tgatgtgtta ttcggaggag ggacccggct gaccgtccta
      421 ggtcagccca aggctgcccc ctcggtcact ctcttcccg
//
LOCUS       KCVO01002172             463 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2112:24409:9567
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002172
VERSION     KCVO01002172.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 463)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2112:24409:9567"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    101..425
                     /note="immunoglobulin light chain variable region"
     V_region        101..425
     V_segment       101..388
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <350..>397
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74201.1"
                     /translation="DYYCQVWDITTDHDVF"
     J_segment       389..425
                     /gene="IGLJ6-1"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        426..>463
                     /gene="IGLC"
BASE COUNT           95 a          138 c          130 g          100 t
ORIGIN      
        1 acatgggggg gcctcaggag gcagcattga cggtgcctca gccatgacct ggacttttct
       61 cctcctcggc ctccttgctt actgcacaga ttctgcggcc tcctatgagc tgactcagcc
      121 accctcggtg tcagtgtccc caggacagac ggccaggatc acctgtgggg gagacaacat
      181 tggaagtaaa aatgtgcact ggtaccagca gaagccaccg caggcccctg tactggtcat
      241 ctattatgat agcgaacggc cctcagggat ccctgagcga ttctctggcg ccaaatcagg
      301 gaacaccgcc accctgatca tcagcggggt cgaggccggg gatgaggctg actattactg
      361 tcaggtgtgg gacattacta ctgatcatga tgtgttcgga agtggcacca agttgaccgt
      421 cctcggtcag cccaaggctt cccccttggt cactctgttc ccg
//
LOCUS       KCVO01002173             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2116:6006:9163
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002173
VERSION     KCVO01002173.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2116:6006:9163"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..434
                     /note="immunoglobulin light chain variable region"
     V_region        104..434
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74202.1"
                     /translation="DYYCSSYTSTSTWLF"
     J_segment       399..434
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        435..>472
                     /gene="IGLC"
BASE COUNT           84 a          162 c          118 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc ctttcctgca ctggaaccag
      181 cagtgacatt ggtggttata accgtgtctc ctggtaccaa caccacccag gcaaagcccc
      241 caaactcatg atttatgacg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcac ttccacttgg ctattcggcg gagggacccg
      421 cctgaccgtc ctaggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01002174             464 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2101:11973:14083
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002174
VERSION     KCVO01002174.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2101:11973:14083"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    102..424
                     /note="immunoglobulin light chain variable region"
     V_region        102..424
     V_segment       102..389
                     /gene="IGLV3-32"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <351..>398
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74203.1"
                     /translation="DYYCQVWDSNNDHIFF"
     J_segment       396..424
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        425..>464
                     /gene="IGLC"
BASE COUNT           87 a          146 c          134 g           97 t
ORIGIN      
        1 acatggggct ggcctcggga agcagccttg gcggtgcctc agccatggcc gggacccttc
       61 tcctcctcgg cctccttgct tactgcacag gctctgcggt ctcctatgag ctgactcagc
      121 caccctcggt gtcagtgtcc ccaggacaga cggccaggat cacctgtggg ggagacaacc
      181 ttggagataa atatctacac tggtaccacc agaagccagc gcaggcccct gtgctggtca
      241 tctactatga tagtgaccgg ccctcatgga tccctgagcg attctctggg tccaagtcag
      301 ggaacaccgc caccctgacc atcagcgggg tcgaggccgg ggatgaggct gactattact
      361 gtcaggtgtg ggacagtaat aatgatcata tctttttcgg aggagggacc cggctgaccg
      421 tcctgggtca gcccaaggct gccccctcgg tcactctctt cccg
//
LOCUS       KCVO01002175             446 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1111:7194:10823
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002175
VERSION     KCVO01002175.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 446)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 446)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1111:7194:10823"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    87..408
                     /note="immunoglobulin light chain variable region"
     V_region        87..408
     V_segment       87..371
                     /gene="IGLV3-15"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <336..>380
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74204.1"
                     /translation="DYYCYSTDSSGNALF"
     J_segment       374..408
                     /gene="IGLJ2-5"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        409..>446
                     /gene="IGLC"
BASE COUNT           94 a          140 c          115 g           97 t
ORIGIN      
        1 tcaggaggca gagctctggg tgtctcacca tggcctggat tcctctccta ctccccatcc
       61 tcactttctg cacaggctct gcagcctcca atgagctgac acagccaccc tcgttgtcag
      121 tgtccccagg acagacggcc aggatcacct gctctggaga tgcattgcca gaaaaatttg
      181 cttattggta ccagcagaaa ccaggccagt cccctgtgct gatcatgtat gaggacagca
      241 aacggccctc tgggatccct gagagattct ctggctccac ctcagggaca gtggccacct
      301 tgactatcag tggggcccag gtggaggatg aagctgacta ctactgttac tcaacagaca
      361 gcagtggtaa tgccttattc ggaggaggga cccggctgac cgtcctaggt cagcccaagg
      421 ctgccccctc ggtcactctc ttcccg
//
LOCUS       KCVO01002176             472 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:2107:13138:3481
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002176
VERSION     KCVO01002176.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 472)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:2107:13138:3481"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    104..432
                     /note="immunoglobulin light chain variable region"
     V_region        104..432
     V_segment       104..398
                     /gene="IGLV2-12"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <362..>406
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74205.1"
                     /translation="DYYCSSYTSSSTWVF"
     J_segment       399..432
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        433..>472
                     /gene="IGLC"
BASE COUNT           86 a          155 c          123 g          108 t
ORIGIN      
        1 acatgggggg gatctcagga ggcagcactc tcaggacgtc tccaccatgg cctgggctct
       61 gctcctcctc accctcctca ctcagggcac aggatcctgg gctcaggctg ccctgactca
      121 gtctccctct gtgtctgggt ctcctggaca gtcggtcacc atttcctgca ctggaaccag
      181 cagtgacatt ggtgattata accgtgtctc ctggtaccaa cagcacccag gcaaagcccc
      241 caaactcatg atttatgagg tcagtgatcg gccctcaggg gtctctgatc gcttctctgg
      301 ttccaagtct ggcaacacgg cctccctgat catctctggg ctccaggctg aggacgaggc
      361 tgattattac tgcagctcat acacaagcag tagcacttgg gtattcggcg gagggacccg
      421 gctgaccgtc cttggtcagc ccaaggctgc cccctcggtc actctcttcc cg
//
LOCUS       KCVO01002177             466 bp    DNA     linear   PRI 03-APR-2019
DEFINITION  TLS: Macaca mulatta isolate RCn16 RLN 28:1:1103:22015:5546
            immunoglobulin light chain variable region, sequence.
ACCESSION   KCVO01002177
VERSION     KCVO01002177.1
DBLINK      BioProject: PRJNA520929
            BioSample: SAMN10872172
            Sequence Read Archive: SRR8582668, SRR8582736
KEYWORDS    TLS; Targeted Locus Study; AIRR; MiAIRR:1.0.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Cirelli,K.M., Carnathan,D.G., Nogal,B., Rodriguez,O.L.,
            Martin,J.T., Upadhyay,A., Enemuo,C.A., Gebru,E.H., Choe,Y.,
            Viviano,F., Nakao,C., Pauthner,M., Reiss,S., Cottrell,C.A.,
            Bastidas,R., Gibson,W., Wolabaugh,A.N., Melo,M.B., Cosette,B.,
            Kuman,V., Patel,N., Tokatlian,T., Menis,S., Kulp,D.W., Burton,D.R.,
            Murrell,B., Bosinger,S.E., Schief,W.R., Ward,A.B., Watson,C.T.,
            Silvestri,G., Irvine,D.J. and Crotty,S.
  TITLE     Slow delivery immunization enhances HIV neutralizing antibody and
            germinal center responses via modulation of immunodominance
  JOURNAL   Unpublished
  REMARK    published on Zenodo 10.5281/zenodo.2573249 19-FEB (2019)
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Upadhyay,A., Wolabaugh,A.N., Patel,N., Cirelli,K.M.,
            Carnathan,D.G., Reiss,S., Silvestri,G., Crotty,S. and Bosinger,S.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAR-2019) Yerkes NHP Core, Yerkes National Primate
            Research Center - Emory University, 954 Gatewood Rd NE, Atlanta, GA
            30329, United States of America
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Macaca mulatta"
                     /mol_type="genomic DNA"
                     /submitter_seqid="28:1:1103:22015:5546"
                     /isolate="RCn16 RLN"
                     /db_xref="taxon:9544"
                     /sex="female"
                     /cell_type="B cells"
                     /tissue_type="R inguinal lymph node"
     misc_feature    95..428
                     /note="immunoglobulin light chain variable region"
     V_region        95..428
     V_segment       95..388
                     /gene="IGLV1-69"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     CDS             <353..>400
                     /function="JUNCTION"
                     /inference="COORDINATES: protein motif:IgBLAST:1.6.1"
                     /codon_start=1
                     /product="immunoglobulin light chain junction region"
                     /protein_id="MOV74206.1"
                     /translation="DYYCSLWDSRLSSRLF"
     J_segment       396..428
                     /gene="IGLJ2-7"
                     /inference="COORDINATES: alignment:IgBLAST:1.6.1"
                     /allele="01"
     C_region        429..>466
                     /gene="IGLC"
BASE COUNT           92 a          150 c          120 g          104 t
ORIGIN      
        1 acatggggga caggaggcag cactcaggac agtctccagc atggcctggt ctctccttct
       61 cactctgctg gttcactgca cagggtcctg ggcccagtct gtgctgacgc agccgccctc
      121 agcatctggg gcccccgggc agagggtcac catctcctgc actgggacca gctccaacat
      181 cggggcgaat tattatgttt cctggtacca gcaattccca ggaacagccc ccaaactcct
      241 catctatgaa aataataagc gaccctcagg ggtttctgac cgattctctg gctccaagtc
      301 tggtacctca gcctccctga ccatctctgg actccaatct gaggatgagg ctgattatta
      361 ctgctcacta tgggatagca ggctgagtag tcggttattc ggcggaggga cccgactgac
      421 cgtcctaggt cagcccaagg ctgccccctc ggtcactctc ttcccg
//
